DRC7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.72500416
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.33159163
3sperm motility (GO:0030317)9.24389285
4fusion of sperm to egg plasma membrane (GO:0007342)8.98370444
5acrosome assembly (GO:0001675)8.02884993
6ventricular system development (GO:0021591)7.97227699
7sperm-egg recognition (GO:0035036)7.87598790
8axoneme assembly (GO:0035082)7.81473577
9multicellular organism reproduction (GO:0032504)7.57683067
10GTP biosynthetic process (GO:0006183)7.48598191
11acrosome reaction (GO:0007340)7.28834513
12binding of sperm to zona pellucida (GO:0007339)7.22978823
13regulation of cilium movement (GO:0003352)7.22261658
14cell-cell recognition (GO:0009988)7.08751093
15cell wall macromolecule catabolic process (GO:0016998)7.02216903
16cell wall macromolecule metabolic process (GO:0044036)7.02216903
17UTP biosynthetic process (GO:0006228)6.82182384
18plasma membrane fusion (GO:0045026)6.70683265
19spermatid development (GO:0007286)6.70612558
20reproduction (GO:0000003)6.23631698
21UTP metabolic process (GO:0046051)6.22097414
22nucleoside diphosphate phosphorylation (GO:0006165)6.18229856
23piRNA metabolic process (GO:0034587)6.11620696
24synaptonemal complex organization (GO:0070193)5.90866363
25male meiosis (GO:0007140)5.82599641
26vitamin transmembrane transport (GO:0035461)5.66424314
27guanosine-containing compound biosynthetic process (GO:1901070)5.62242662
28single fertilization (GO:0007338)5.54605368
29negative regulation of inclusion body assembly (GO:0090084)5.49634487
30primary alcohol catabolic process (GO:0034310)5.49203611
31microtubule severing (GO:0051013)5.47684269
32left/right axis specification (GO:0070986)5.42149018
33synaptonemal complex assembly (GO:0007130)5.41935454
34CTP metabolic process (GO:0046036)5.27024435
35CTP biosynthetic process (GO:0006241)5.27024435
36intraciliary transport (GO:0042073)4.94716646
37pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.93091093
38diterpenoid biosynthetic process (GO:0016102)4.88961656
39centriole assembly (GO:0098534)4.88003123
40sperm capacitation (GO:0048240)4.78896443
41fertilization (GO:0009566)4.77028787
42ethanol metabolic process (GO:0006067)4.69701158
43spermatogenesis (GO:0007283)4.65660376
44male gamete generation (GO:0048232)4.64003147
45regulation of interleukin-5 production (GO:0032674)4.63044145
46pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.59845571
47cilium organization (GO:0044782)4.51929032
48regulation of inclusion body assembly (GO:0090083)4.51896851
49pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.49815362
50left/right pattern formation (GO:0060972)4.43352912
51one-carbon compound transport (GO:0019755)4.38154478
52response to xenobiotic stimulus (GO:0009410)4.35909756
53gamete generation (GO:0007276)4.27433673
54male meiosis I (GO:0007141)4.22094934
55cilium assembly (GO:0042384)4.21169766
56pyrimidine-containing compound transmembrane transport (GO:0072531)4.19288826
57microtubule bundle formation (GO:0001578)4.15106515
58microtubule-based movement (GO:0007018)4.10992726
59pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.09311194
60microtubule depolymerization (GO:0007019)4.05641478
61protein polyglutamylation (GO:0018095)4.00855501
62regulation of microtubule-based movement (GO:0060632)3.97863385
63meiotic cell cycle (GO:0051321)3.95284372
64cilium morphogenesis (GO:0060271)3.95177040
65cellular process involved in reproduction in multicellular organism (GO:0022412)3.80650989
66germ cell development (GO:0007281)3.79806414
67microtubule polymerization or depolymerization (GO:0031109)3.78201531
68protein localization to cilium (GO:0061512)3.77480194
69spermatid nucleus differentiation (GO:0007289)3.76731505
70chromosome organization involved in meiosis (GO:0070192)3.75793834
71cellular component assembly involved in morphogenesis (GO:0010927)3.75314167
72meiosis I (GO:0007127)3.75100135
73regulation of interleukin-13 production (GO:0032656)3.74132472
74lung epithelium development (GO:0060428)3.70375094
75meiotic nuclear division (GO:0007126)3.68720931
76diol metabolic process (GO:0034311)3.59361319
77DNA methylation involved in gamete generation (GO:0043046)3.55069804
78negative regulation of T cell differentiation in thymus (GO:0033085)3.51670280
79ethanol oxidation (GO:0006069)3.48661016
80terpenoid biosynthetic process (GO:0016114)3.45691689
81glutathione derivative biosynthetic process (GO:1901687)3.39559285
82glutathione derivative metabolic process (GO:1901685)3.39559285
83retinal cone cell development (GO:0046549)3.37084252
84retinoic acid metabolic process (GO:0042573)3.36278430
85retinal rod cell development (GO:0046548)3.35854635
86multicellular organismal reproductive process (GO:0048609)3.35309541
87organic cation transport (GO:0015695)3.33272438
88cell recognition (GO:0008037)3.32493457
89nucleosome disassembly (GO:0006337)3.31052449
90protein-DNA complex disassembly (GO:0032986)3.31052449
91sphingoid metabolic process (GO:0046519)3.27480367
92regulation of germinal center formation (GO:0002634)3.27170881
93glomerular epithelial cell development (GO:0072310)3.22556489
94nucleotide phosphorylation (GO:0046939)3.18156797
95chromosome condensation (GO:0030261)3.15789244
96pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.14682442
97protein localization to chromosome, centromeric region (GO:0071459)3.13128133
98calcium ion-dependent exocytosis (GO:0017156)3.12662751
99mitotic sister chromatid cohesion (GO:0007064)3.12448418
100phosphatidylethanolamine biosynthetic process (GO:0006646)3.12210676
101establishment of apical/basal cell polarity (GO:0035089)3.10712574
102tolerance induction (GO:0002507)3.06216719
103photoreceptor cell maintenance (GO:0045494)3.05537208
104translesion synthesis (GO:0019985)3.04101516
105cytoplasmic microtubule organization (GO:0031122)3.03596511
106DNA packaging (GO:0006323)3.02325968
107negative regulation of organelle assembly (GO:1902116)3.01517489
108regulation of histone H3-K9 methylation (GO:0051570)3.01244557
109cellular hyperosmotic response (GO:0071474)3.00016423
110sphingosine metabolic process (GO:0006670)2.99659194
111pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.99411243
112phosphatidylethanolamine metabolic process (GO:0046337)2.99194838
113exogenous drug catabolic process (GO:0042738)2.98060770
114negative regulation of immunoglobulin mediated immune response (GO:0002890)2.96131635
115negative regulation of B cell mediated immunity (GO:0002713)2.96131635
116determination of left/right symmetry (GO:0007368)2.92645675
117nucleoside diphosphate metabolic process (GO:0009132)2.88912091
118cell projection assembly (GO:0030031)2.88388350
119lateral ventricle development (GO:0021670)2.87127083
120intra-S DNA damage checkpoint (GO:0031573)2.86733832
121O-glycan processing (GO:0016266)2.86043514
122positive regulation of tolerance induction (GO:0002645)2.85713228
123retinol metabolic process (GO:0042572)2.84024353
124DNA synthesis involved in DNA repair (GO:0000731)2.81115580
125centriole replication (GO:0007099)2.80581176
126gene silencing by RNA (GO:0031047)2.79661302
127determination of bilateral symmetry (GO:0009855)2.78195637
128V(D)J recombination (GO:0033151)2.76818808
129negative regulation of humoral immune response (GO:0002921)2.76692147
130regulation of spindle checkpoint (GO:0090231)2.74102855
131DNA ligation (GO:0006266)2.73475995
132pyrimidine ribonucleotide metabolic process (GO:0009218)2.73426070
133phosphatidylcholine biosynthetic process (GO:0006656)2.73244151
134specification of symmetry (GO:0009799)2.71080521
135DNA replication-dependent nucleosome assembly (GO:0006335)2.70846337
136establishment of monopolar cell polarity (GO:0061162)2.70135928
137establishment or maintenance of monopolar cell polarity (GO:0061339)2.70135928
138negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.69706764
139primary alcohol metabolic process (GO:0034308)2.69650719
140excretion (GO:0007588)2.62966525
141microtubule-based process (GO:0007017)2.61657743
142smoothened signaling pathway (GO:0007224)2.61264910
143organelle assembly (GO:0070925)2.59584460
144androgen biosynthetic process (GO:0006702)2.58933715
145glutathione metabolic process (GO:0006749)2.47990797
146CDP-diacylglycerol biosynthetic process (GO:0016024)2.46837538
147drug catabolic process (GO:0042737)2.44194192
148regulation of autophagic vacuole assembly (GO:2000785)2.42882183
149carnitine metabolic process (GO:0009437)2.41917880
150establishment of planar polarity (GO:0001736)2.38466732
151establishment of tissue polarity (GO:0007164)2.38466732
152regulation of cilium assembly (GO:1902017)2.38244828
153hydrogen peroxide biosynthetic process (GO:0050665)2.34816602
154cilium or flagellum-dependent cell motility (GO:0001539)15.0809851
155axonemal dynein complex assembly (GO:0070286)13.1492480
156cilium movement (GO:0003341)12.5918447
157epithelial cilium movement (GO:0003351)11.1207970

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.49041418
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.95445666
3E2F7_22180533_ChIP-Seq_HELA_Human4.92563375
4EZH2_22144423_ChIP-Seq_EOC_Human4.34573078
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.21163061
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.73196981
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse3.15717359
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.93746297
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.76123178
10FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.50154161
11GATA1_26923725_Chip-Seq_HPCs_Mouse2.47535502
12VDR_22108803_ChIP-Seq_LS180_Human2.40329541
13AR_21572438_ChIP-Seq_LNCaP_Human2.09668269
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.97503502
15ESR1_20079471_ChIP-ChIP_T-47D_Human1.95151382
16STAT6_21828071_ChIP-Seq_BEAS2B_Human1.87172368
17PIAS1_25552417_ChIP-Seq_VCAP_Human1.86257874
18IGF1R_20145208_ChIP-Seq_DFB_Human1.82380161
19CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.81856716
20SCL_19346495_ChIP-Seq_HPC-7_Human1.81787579
21ARNT_22903824_ChIP-Seq_MCF-7_Human1.78311942
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.76962113
23GBX2_23144817_ChIP-Seq_PC3_Human1.76655789
24FLI1_27457419_Chip-Seq_LIVER_Mouse1.75330376
25E2F4_17652178_ChIP-ChIP_JURKAT_Human1.71968954
26PCGF2_27294783_Chip-Seq_ESCs_Mouse1.64544988
27AHR_22903824_ChIP-Seq_MCF-7_Human1.63069755
28EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.61089606
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.60618508
30FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.59523214
31WDR5_24793694_ChIP-Seq_LNCAP_Human1.58842673
32BCAT_22108803_ChIP-Seq_LS180_Human1.57428300
33SMAD4_21799915_ChIP-Seq_A2780_Human1.55834070
34PCGF2_27294783_Chip-Seq_NPCs_Mouse1.53769730
35SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.53367647
36ER_23166858_ChIP-Seq_MCF-7_Human1.52833786
37SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.51883515
38SOX2_22085726_ChIP-Seq_NPCs_Mouse1.51538663
39NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48153896
40TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.47248258
41FOXM1_26456572_ChIP-Seq_MCF-7_Human1.45900233
42ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.44930568
43TP63_23658742_ChIP-Seq_EP156T_Human1.44642525
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43700154
45CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41878196
46TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.39685523
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.39601068
48STAT3_23295773_ChIP-Seq_U87_Human1.38682214
49AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.35889100
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.35183843
51SMAD4_21741376_ChIP-Seq_EPCs_Human1.34719791
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.30303008
53P53_21459846_ChIP-Seq_SAOS-2_Human1.30078238
54TP53_18474530_ChIP-ChIP_U2OS_Human1.29654116
55RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29510242
56FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26652461
57TDRD3_21172665_ChIP-Seq_MCF-7_Human1.25436804
58FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.24971579
59PHF8_20622853_ChIP-Seq_HELA_Human1.23274799
60KAP1_22055183_ChIP-Seq_ESCs_Mouse1.22394661
61ETV1_20927104_ChIP-Seq_GIST48_Human1.21486251
62MYB_26560356_Chip-Seq_TH2_Human1.20588644
63TCF4_22108803_ChIP-Seq_LS180_Human1.19636361
64RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.19001469
65CEBPB_22108803_ChIP-Seq_LS180_Human1.18988443
66CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.18287938
67HNFA_21074721_ChIP-Seq_CACO-2_Human1.17763298
68ERG_20517297_ChIP-Seq_VCAP_Human1.17683585
69NFE2_27457419_Chip-Seq_LIVER_Mouse1.17620470
70TBL1_22424771_ChIP-Seq_293T_Human1.17607043
71TCF4_23295773_ChIP-Seq_U87_Human1.16641306
72GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16245103
73NANOG_19829295_ChIP-Seq_ESCs_Human1.15694443
74SOX2_19829295_ChIP-Seq_ESCs_Human1.15694443
75P300_19829295_ChIP-Seq_ESCs_Human1.15431761
76AR_25329375_ChIP-Seq_VCAP_Human1.15006321
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.14762312
78OCT4_20526341_ChIP-Seq_ESCs_Human1.13783456
79GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.13266411
80NFYA_21822215_ChIP-Seq_K562_Human1.13187373
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.13067197
82EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.13057884
83EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12752416
84TAL1_26923725_Chip-Seq_HPCs_Mouse1.12471342
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.12355918
86GATA3_21867929_ChIP-Seq_CD8_Mouse1.12298389
87GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.12296645
88PRDM14_20953172_ChIP-Seq_ESCs_Human1.11454327
89FOXA1_25552417_ChIP-Seq_VCAP_Human1.11118006
90GATA4_25053715_ChIP-Seq_YYC3_Human1.10622285
91RBPJ_21746931_ChIP-Seq_IB4_Human1.10372288
92NANOG_20526341_ChIP-Seq_ESCs_Human1.09786952
93NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09354074
94CTNNB1_20460455_ChIP-Seq_HCT116_Human1.09242708
95PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.08769309
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08634208
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08160805
98OCT1_27270436_Chip-Seq_PROSTATE_Human1.08054559
99GATA3_21878914_ChIP-Seq_MCF-7_Human1.07958356
100STAT1_20625510_ChIP-Seq_HELA_Human1.07931512
101PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.07673848
102CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07488611
103AR_20517297_ChIP-Seq_VCAP_Human1.07452027
104CDX2_22108803_ChIP-Seq_LS180_Human1.07199090
105LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07118010
106ELK4_26923725_Chip-Seq_MESODERM_Mouse1.07108444
107HOXB7_26014856_ChIP-Seq_BT474_Human1.06141979
108SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05659823
109SMAD3_21741376_ChIP-Seq_HESCs_Human1.05636902
110LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.05566082
111IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05318891
112CBP_20019798_ChIP-Seq_JUKART_Human1.05318891
113GATA1_19941826_ChIP-Seq_K562_Human1.04901622
114NFYB_21822215_ChIP-Seq_K562_Human1.04116500
115TAF15_26573619_Chip-Seq_HEK293_Human1.04030083
116LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.03837955
117RUNX2_22187159_ChIP-Seq_PCA_Human1.03104524
118STAT1_17558387_ChIP-Seq_HELA_Human1.02911042
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02342484
120MYB_26560356_Chip-Seq_TH1_Human1.01815986
121FLI1_21867929_ChIP-Seq_TH2_Mouse1.01712192
122TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.01496264
123TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.01048947
124VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.00193808
125NCOR_22424771_ChIP-Seq_293T_Human1.00056610
126CBX2_22325352_ChIP-Seq_293T-Rex_Human1.00008146
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.99624591
128MYC_19829295_ChIP-Seq_ESCs_Human0.98982220
129MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98265760
130SMAD4_21741376_ChIP-Seq_HESCs_Human0.97898628
131MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97362459
132TP63_22573176_ChIP-Seq_HFKS_Human0.97019795
133CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96653832
134FOXA1_21572438_ChIP-Seq_LNCaP_Human0.96652041
135YY1_22570637_ChIP-Seq_MALME-3M_Human0.96443894
136FUS_26573619_Chip-Seq_HEK293_Human0.96293732
137GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95561528
138GATA6_21074721_ChIP-Seq_CACO-2_Human0.95115211
139RAD21_21589869_ChIP-Seq_MESCs_Mouse0.95034096
140PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94763802
141TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94439118
142DROSHA_22980978_ChIP-Seq_HELA_Human0.93485772
143SPI1_26923725_Chip-Seq_HPCs_Mouse0.93286628
144PKCTHETA_26484144_Chip-Seq_BREAST_Human0.91557448
145SMRT_27268052_Chip-Seq_Bcells_Human0.90918922
146OCT4_18555785_Chip-Seq_ESCs_Mouse0.88676948
147FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.88659108
148GF1_26923725_Chip-Seq_HPCs_Mouse0.88131997
149TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87451457
150POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87451457
151STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87175500
152PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.87115867
153RUNX1_26923725_Chip-Seq_HPCs_Mouse0.87057636
154SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.86763995
155CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.86410246
156GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.86351493
157SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86012331
158SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84960985
159MYC_22102868_ChIP-Seq_BL_Human0.84952892
160CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.84231660
161RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.84229565
162KDM2B_26808549_Chip-Seq_REH_Human0.83334734
163FOXA1_27270436_Chip-Seq_PROSTATE_Human0.83014382
164FOXA1_25329375_ChIP-Seq_VCAP_Human0.83014382
165CBX2_27304074_Chip-Seq_ESCs_Mouse0.82639238
166VDR_21846776_ChIP-Seq_THP-1_Human0.82503057
167AR_21909140_ChIP-Seq_LNCAP_Human0.81899009
168CRX_20693478_ChIP-Seq_RETINA_Mouse0.81587107
169GATA3_21867929_ChIP-Seq_TH1_Mouse0.81545498
170ZNF274_21170338_ChIP-Seq_K562_Hela0.81204272
171SOX9_26525672_Chip-Seq_HEART_Mouse0.81190805
172SPI1_20517297_ChIP-Seq_HL60_Human0.80925087
173TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.80739378
174PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80705379
175GATA1_19941827_ChIP-Seq_MEL86_Mouse0.79936585
176OCT4_21477851_ChIP-Seq_ESCs_Mouse0.78923592
177ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.78863991
178RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.78436787
179EZH2_27294783_Chip-Seq_NPCs_Mouse0.78296105

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok5.32625111
2MP0002132_abnormal_respiratory_system4.97456069
3MP0008004_abnormal_stomach_pH4.63739913
4MP0003698_abnormal_male_reproductive4.42807278
5MP0001929_abnormal_gametogenesis4.38740715
6MP0002653_abnormal_ependyma_morphology3.73232845
7MP0008877_abnormal_DNA_methylation3.56060624
8MP0004043_abnormal_pH_regulation3.45622791
9MP0002210_abnormal_sex_determination2.88559141
10MP0009780_abnormal_chondrocyte_physiolo2.88223862
11MP0002277_abnormal_respiratory_mucosa2.74655420
12MP0005623_abnormal_meninges_morphology2.61758648
13MP0008057_abnormal_DNA_replication2.52769570
14MP0002161_abnormal_fertility/fecundity2.52221473
15MP0002837_dystrophic_cardiac_calcinosis2.50995165
16MP0002396_abnormal_hematopoietic_system2.47339020
17MP0001145_abnormal_male_reproductive2.45731857
18MP0005377_hearing/vestibular/ear_phenot2.43817593
19MP0003878_abnormal_ear_physiology2.43817593
20MP0008058_abnormal_DNA_repair2.42752113
21MP0000383_abnormal_hair_follicle2.28816765
22MP0010094_abnormal_chromosome_stability2.24201447
23MP0000653_abnormal_sex_gland2.17389636
24MP0002160_abnormal_reproductive_system2.16569688
25MP0003136_yellow_coat_color2.00362782
26MP0005410_abnormal_fertilization10.6761172
27MP0008789_abnormal_olfactory_epithelium1.99740202
28MP0003011_delayed_dark_adaptation1.97922815
29MP0002928_abnormal_bile_duct1.97522382
30MP0003045_fibrosis1.93525206
31MP0003195_calcinosis1.92660414
32MP0009278_abnormal_bone_marrow1.86525510
33MP0005670_abnormal_white_adipose1.78198728
34MP0004133_heterotaxia1.75200423
35MP0003879_abnormal_hair_cell1.73382115
36MP0005365_abnormal_bile_salt1.73160061
37MP0008995_early_reproductive_senescence1.72951653
38MP0005171_absent_coat_pigmentation1.69895478
39MP0005395_other_phenotype1.69887168
40MP0004808_abnormal_hematopoietic_stem1.69439539
41MP0005647_abnormal_sex_gland1.66779433
42MP0010678_abnormal_skin_adnexa1.66362850
43MP0003786_premature_aging1.61494109
44MP0005083_abnormal_biliary_tract1.61366530
45MP0005085_abnormal_gallbladder_physiolo1.58233570
46MP0005075_abnormal_melanosome_morpholog1.56940256
47MP0005551_abnormal_eye_electrophysiolog1.52522896
48MP0005397_hematopoietic_system_phenotyp1.49367905
49MP0001545_abnormal_hematopoietic_system1.49367905
50MP0002735_abnormal_chemical_nociception1.47260007
51MP0001873_stomach_inflammation1.46769035
52MP0002282_abnormal_trachea_morphology1.44970415
53MP0002876_abnormal_thyroid_physiology1.40102337
54MP0000465_gastrointestinal_hemorrhage1.38832392
55MP0003111_abnormal_nucleus_morphology1.36424474
56MP0008872_abnormal_physiological_respon1.36311545
57MP0003656_abnormal_erythrocyte_physiolo1.36237816
58MP0005499_abnormal_olfactory_system1.31804930
59MP0005394_taste/olfaction_phenotype1.31804930
60MP0002638_abnormal_pupillary_reflex1.27347530
61MP0001958_emphysema1.20014063
62MP0005389_reproductive_system_phenotype1.18344446
63MP0005636_abnormal_mineral_homeostasis1.17023553
64MP0001485_abnormal_pinna_reflex1.16604497
65MP0002909_abnormal_adrenal_gland1.14590078
66MP0005645_abnormal_hypothalamus_physiol1.11796817
67MP0002405_respiratory_system_inflammati1.10879067
68MP0000685_abnormal_immune_system1.04852741
69MP0008007_abnormal_cellular_replicative1.03164047
70MP0010307_abnormal_tumor_latency1.01750682
71MP0005646_abnormal_pituitary_gland0.98151313
72MP0003943_abnormal_hepatobiliary_system0.98132157
73MP0000566_synostosis0.96853105
74MP0003718_maternal_effect0.94017757
75MP0003252_abnormal_bile_duct0.90344497
76MP0001663_abnormal_digestive_system0.88194467
77MP0010155_abnormal_intestine_physiology0.88138024
78MP0000703_abnormal_thymus_morphology0.87977690
79MP0001970_abnormal_pain_threshold0.86576110
80MP0001851_eye_inflammation0.86347539
81MP0001664_abnormal_digestion0.85606823
82MP0003077_abnormal_cell_cycle0.85223007
83MP0006054_spinal_hemorrhage0.85205748
84MP0003303_peritoneal_inflammation0.83428035
85MP0001727_abnormal_embryo_implantation0.83140038
86MP0000678_abnormal_parathyroid_gland0.82878456
87MP0001984_abnormal_olfaction0.82591044
88MP0000026_abnormal_inner_ear0.82365740
89MP0005220_abnormal_exocrine_pancreas0.82353478
90MP0009643_abnormal_urine_homeostasis0.82322759
91MP0001765_abnormal_ion_homeostasis0.82270184
92MP0003890_abnormal_embryonic-extraembry0.81580551
93MP0002398_abnormal_bone_marrow0.80093740
94MP0004233_abnormal_muscle_weight0.79829949
95MP0006036_abnormal_mitochondrial_physio0.79574273
96MP0002229_neurodegeneration0.78036560
97MP0005248_abnormal_Harderian_gland0.77184437
98MP0002136_abnormal_kidney_physiology0.77126756
99MP0000689_abnormal_spleen_morphology0.76859990
100MP0002102_abnormal_ear_morphology0.75645661
101MP0000230_abnormal_systemic_arterial0.75084265
102MP0004381_abnormal_hair_follicle0.75008313
103MP0001963_abnormal_hearing_physiology0.72618458
104MP0000470_abnormal_stomach_morphology0.72145986
105MP0000490_abnormal_crypts_of0.71647015
106MP0001800_abnormal_humoral_immune0.71570953
107MP0001756_abnormal_urination0.70276593
108MP0005381_digestive/alimentary_phenotyp0.70226452
109MP0001486_abnormal_startle_reflex0.69602498
110MP0005666_abnormal_adipose_tissue0.69587170
111MP0001324_abnormal_eye_pigmentation0.69170791
112MP0009046_muscle_twitch0.68740701
113MP0005165_increased_susceptibility_to0.68315746
114MP0002734_abnormal_mechanical_nocicepti0.67804925
115MP0005310_abnormal_salivary_gland0.67519585
116MP0010329_abnormal_lipoprotein_level0.65942387
117MP0002168_other_aberrant_phenotype0.64772915
118MP0008961_abnormal_basal_metabolism0.63830413
119MP0009384_cardiac_valve_regurgitation0.62887418
120MP0000313_abnormal_cell_death0.62664813
121MP0003950_abnormal_plasma_membrane0.62548753
122MP0002722_abnormal_immune_system0.62526402
123MP0003693_abnormal_embryo_hatching0.62343217
124MP0001968_abnormal_touch/_nociception0.61650558
125MP0002019_abnormal_tumor_incidence0.61444464
126MP0002233_abnormal_nose_morphology0.61156839
127MP0010386_abnormal_urinary_bladder0.60164953
128MP0000716_abnormal_immune_system0.58434187
129MP0003646_muscle_fatigue0.57429934
130MP0001346_abnormal_lacrimal_gland0.56937905
131MP0009745_abnormal_behavioral_response0.55514019
132MP0005464_abnormal_platelet_physiology0.55108837
133MP0002452_abnormal_antigen_presenting0.54382944
134MP0001944_abnormal_pancreas_morphology0.53599194
135MP0002133_abnormal_respiratory_system0.53416036
136MP0005388_respiratory_system_phenotype0.53416036
137MP0005195_abnormal_posterior_eye0.53236347
138MP0000350_abnormal_cell_proliferation0.52979063
139MP0003866_abnormal_defecation0.52553390
140MP0005164_abnormal_response_to0.52165832
141MP0005408_hypopigmentation0.51959095
142MP0002420_abnormal_adaptive_immunity0.51657846
143MP0005076_abnormal_cell_differentiation0.51477034
144MP0001819_abnormal_immune_cell0.50670760
145MP0009765_abnormal_xenobiotic_induced0.50621455
146MP0001270_distended_abdomen0.50574882
147MP0002723_abnormal_immune_serum0.50333932
148MP0003763_abnormal_thymus_physiology0.50126909
149MP0000631_abnormal_neuroendocrine_gland0.50041876
150MP0005391_vision/eye_phenotype0.49029268
151MP0000462_abnormal_digestive_system0.49008680
152MP0002272_abnormal_nervous_system0.48718656
153MP0003861_abnormal_nervous_system0.48389944
154MP0002970_abnormal_white_adipose0.48133113
155MP0004019_abnormal_vitamin_homeostasis0.47735168
156MP0001666_abnormal_nutrient_absorption0.47224830
157MP0005387_immune_system_phenotype0.46664594
158MP0001790_abnormal_immune_system0.46664594
159MP0001879_abnormal_lymphatic_vessel0.46229932
160MP0005253_abnormal_eye_physiology0.46081228
161MP0008932_abnormal_embryonic_tissue0.45423564
162MP0002429_abnormal_blood_cell0.44698644
163MP0002095_abnormal_skin_pigmentation0.44131015
164MP0009115_abnormal_fat_cell0.43985591
165MP0001835_abnormal_antigen_presentation0.43001810
166MP0003699_abnormal_female_reproductive0.42170462
167MP0002084_abnormal_developmental_patter0.40172266
168MP0003633_abnormal_nervous_system0.39831205
169MP0003300_gastrointestinal_ulcer0.39743380
170MP0004811_abnormal_neuron_physiology0.39417342

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.79409746
2Abnormal respiratory epithelium morphology (HP:0012253)9.15970799
3Abnormal respiratory motile cilium morphology (HP:0005938)9.15970799
4Rhinitis (HP:0012384)9.10169151
5Chronic bronchitis (HP:0004469)7.06391863
6Nasal polyposis (HP:0100582)6.33710546
7Bronchiectasis (HP:0002110)5.38760804
8Abnormality of the nasal mucosa (HP:0000433)5.35568194
9Infertility (HP:0000789)4.79193246
10Bronchitis (HP:0012387)4.71292469
11Male infertility (HP:0003251)4.13360624
12Recurrent sinusitis (HP:0011108)4.05981343
13Nephronophthisis (HP:0000090)3.71412938
14Recurrent otitis media (HP:0000403)3.49057227
15Chronic sinusitis (HP:0011109)3.47550884
16Tubulointerstitial nephritis (HP:0001970)3.42986323
17True hermaphroditism (HP:0010459)3.25997693
18Pancreatic fibrosis (HP:0100732)3.20121517
19Recurrent bronchitis (HP:0002837)3.14559539
20Abnormality of the renal medulla (HP:0100957)2.75185038
21Hyperactive renin-angiotensin system (HP:0000841)2.70854414
22Abnormality of midbrain morphology (HP:0002418)2.56481875
23Molar tooth sign on MRI (HP:0002419)2.56481875
24Atelectasis (HP:0100750)2.56069935
25Abnormal biliary tract physiology (HP:0012439)2.55178818
26Bile duct proliferation (HP:0001408)2.55178818
27Chronic hepatic failure (HP:0100626)2.53637814
28Postaxial foot polydactyly (HP:0001830)2.53392589
29Occipital encephalocele (HP:0002085)2.49544372
30Medial flaring of the eyebrow (HP:0010747)2.46787482
31Supernumerary spleens (HP:0009799)2.44298469
32Abnormality of permanent molar morphology (HP:0011071)2.42939637
33Abnormality of the dental root (HP:0006486)2.42939637
34Taurodontia (HP:0000679)2.42939637
35Cystic liver disease (HP:0006706)2.36653252
36Tubulointerstitial abnormality (HP:0001969)2.26208004
37Pancreatic cysts (HP:0001737)2.25642997
38Abnormality of molar (HP:0011077)2.24633384
39Abnormality of molar morphology (HP:0011070)2.24633384
40Congenital hepatic fibrosis (HP:0002612)2.22917222
41Abnormality of the dental pulp (HP:0006479)2.20421703
42Aplasia/Hypoplasia of the tongue (HP:0010295)2.11284152
43Tubular atrophy (HP:0000092)2.11147079
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.08158380
45Agammaglobulinemia (HP:0004432)2.00351669
46Hypoplasia of the capital femoral epiphysis (HP:0003090)2.00321407
47Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.8386224
48Abnormal respiratory motile cilium physiology (HP:0012261)10.7940587
49Dynein arm defect of respiratory motile cilia (HP:0012255)10.3653193
50Absent/shortened dynein arms (HP:0200106)10.3653193
51Amyotrophic lateral sclerosis (HP:0007354)1.99719112
52Decreased circulating renin level (HP:0003351)1.97957149
53Gait imbalance (HP:0002141)1.90855636
54Congenital primary aphakia (HP:0007707)1.90490398
55Broad distal phalanx of finger (HP:0009836)1.90023215
56Cellulitis (HP:0100658)1.83733567
57Abnormal rod and cone electroretinograms (HP:0008323)1.82456987
58Abnormality of dentin (HP:0010299)1.82095619
59Aplasia/Hypoplasia of the spleen (HP:0010451)1.80886583
60Bell-shaped thorax (HP:0001591)1.79761340
61Renal salt wasting (HP:0000127)1.77001602
62Hyperkalemia (HP:0002153)1.76973670
63Decreased central vision (HP:0007663)1.76125136
64Stage 5 chronic kidney disease (HP:0003774)1.75239550
65Median cleft lip (HP:0000161)1.74460827
66Oculomotor apraxia (HP:0000657)1.72844157
67Male pseudohermaphroditism (HP:0000037)1.72375948
68Asplenia (HP:0001746)1.71296050
69Abnormality of the lower motor neuron (HP:0002366)1.69724328
70Hyperaldosteronism (HP:0000859)1.66901126
71Anencephaly (HP:0002323)1.66478695
72Abnormal spermatogenesis (HP:0008669)1.66396817
73Fibular hypoplasia (HP:0003038)1.66261600
74Facial cleft (HP:0002006)1.65619882
75Nephrogenic diabetes insipidus (HP:0009806)1.61148616
76Hypokalemic alkalosis (HP:0001949)1.57442892
77Abnormality of macular pigmentation (HP:0008002)1.57331028
78Abnormality of the renal cortex (HP:0011035)1.56725501
79Sclerocornea (HP:0000647)1.54036260
80Abnormal drinking behavior (HP:0030082)1.53507011
81Polydipsia (HP:0001959)1.53507011
82Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.52478908
83Absent epiphyses (HP:0010577)1.52478908
84Postaxial hand polydactyly (HP:0001162)1.51469938
85Abnormality of renin-angiotensin system (HP:0000847)1.49301584
86Abnormality of chloride homeostasis (HP:0011422)1.47908396
87Purpura (HP:0000979)1.47898813
88Preaxial hand polydactyly (HP:0001177)1.43121034
89Tubulointerstitial fibrosis (HP:0005576)1.41849130
90Abnormality of renal excretion (HP:0011036)1.41695013
91Constricted visual fields (HP:0001133)1.39512044
92Chronic otitis media (HP:0000389)1.38704740
9311 pairs of ribs (HP:0000878)1.37574626
94Poor coordination (HP:0002370)1.37388523
95Thyroiditis (HP:0100646)1.36168803
96Small epiphyses (HP:0010585)1.35024941
97Short ribs (HP:0000773)1.33871923
98Degeneration of anterior horn cells (HP:0002398)1.33860692
99Abnormality of the anterior horn cell (HP:0006802)1.33860692
100Bony spicule pigmentary retinopathy (HP:0007737)1.32569363
101Prolonged bleeding time (HP:0003010)1.32282948
102Cone-rod dystrophy (HP:0000548)1.31755677
103B lymphocytopenia (HP:0010976)1.26478539
104Abnormality of B cell number (HP:0010975)1.26478539
105Verrucae (HP:0200043)1.25644401
106Papilloma (HP:0012740)1.25644401
107Retinitis pigmentosa (HP:0000510)1.25591858
108Degeneration of the lateral corticospinal tracts (HP:0002314)1.25489439
109Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.25489439
110Portal hypertension (HP:0001409)1.25488492
111Flattened epiphyses (HP:0003071)1.24771468
112Genital tract atresia (HP:0001827)1.24762475
113Impulsivity (HP:0100710)1.22447382
114Short femoral neck (HP:0100864)1.22417398
115Amelogenesis imperfecta (HP:0000705)1.21386371
116Furrowed tongue (HP:0000221)1.21306254
117Abnormality of the hepatic vasculature (HP:0006707)1.21070715
118Vaginal atresia (HP:0000148)1.21055813
119Ventricular fibrillation (HP:0001663)1.17444253
120Nephropathy (HP:0000112)1.15325628
121Sloping forehead (HP:0000340)1.14987134
122Absent frontal sinuses (HP:0002688)1.14383766
123Aplasia/Hypoplasia of the lens (HP:0008063)1.13699356
124Polyuria (HP:0000103)1.13440813
125Absent speech (HP:0001344)1.13012738
126Short thorax (HP:0010306)1.12391006
127Menorrhagia (HP:0000132)1.09556047
128Central scotoma (HP:0000603)1.06174060
129Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.04828386
130Hyponatremia (HP:0002902)1.01376977
131Abnormality of monocarboxylic acid metabolism (HP:0010996)0.99473102
132Nonprogressive disorder (HP:0003680)0.98751319
133Severe visual impairment (HP:0001141)0.98208743
134Prominent nasal bridge (HP:0000426)0.97976289
135Petechiae (HP:0000967)0.97663438

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK45.80157428
2PDK35.80157428
3EEF2K4.85528771
4LATS14.57486548
5MAP3K103.78418012
6STK38L3.49343817
7PDK23.48659333
8TESK13.47715499
9FRK3.35278746
10PNCK3.20100572
11MAPK153.12707680
12PINK12.74424458
13ICK2.67597839
14EPHA22.50656486
15PRKD32.41469790
16WEE12.31006751
17NEK22.01354163
18PTK2B1.98441144
19MAP3K21.84057899
20BRSK21.83826579
21TLK11.80061563
22CDC71.67502032
23MAP4K21.66149116
24STK241.61665691
25STK101.60258641
26STK391.59745188
27ZAK1.57129864
28GRK11.49895859
29CCNB11.49568178
30MAPKAPK31.48125160
31ACVR1B1.42084521
32NTRK21.41324733
33MST41.40480877
34ADRBK21.40321462
35WNK41.38246756
36MYLK1.34573422
37BMPR1B1.33532673
38NME11.30755478
39LATS21.25151865
40MAPKAPK51.23192325
41SIK31.16931901
42TTK1.12947871
43BRSK11.10541811
44BTK1.06634932
45OXSR11.05683044
46RPS6KB21.04030639
47INSRR1.00091564
48DYRK30.98250830
49BCR0.97216655
50CSF1R0.96631996
51MARK30.90106533
52FES0.89271804
53CDK40.86890882
54CSK0.84792952
55EPHA30.82387847
56MAP3K30.80886365
57CLK10.80789499
58PRKAA20.80579024
59PDK10.79244908
60CHEK20.76719654
61PTK60.76362481
62LRRK20.76255794
63FER0.75113984
64CAMKK10.75032129
65EIF2AK30.72809170
66ADRBK10.72283393
67PASK0.70956883
68TESK20.70333392
69GRK60.68587593
70NEK60.68448597
71SIK20.67960002
72MAPK40.67056223
73VRK10.66645725
74PRKCI0.66441348
75ERBB20.64883231
76ATR0.64719622
77MAP2K20.64442490
78NTRK10.63367509
79WNK30.61711918
80MAPK130.61507599
81TRPM70.59319528
82MAP3K70.58395735
83RIPK40.57091295
84MAPK120.56906046
85STK40.55169201
86PLK10.55106256
87STK30.54754616
88TRIM280.52928317
89TGFBR20.52468890
90MELK0.52004192
91BUB10.51399596
92PAK40.50534070
93PLK20.50304880
94CDK120.50140772
95PRKCG0.50100591
96MAP4K10.49263157
97MST1R0.48910930
98WNK10.48887183
99CHEK10.47772302
100SIK10.46596268
101SYK0.44564094
102NLK0.43701113
103BMX0.43158657
104NTRK30.41935043
105DYRK1B0.41276633
106ERN10.41235782
107PAK20.40804808
108RPS6KB10.39686171
109PRKCE0.39218052
110GRK50.38963272
111RPS6KA20.38413147
112MAPK110.37988323
113TNK20.37774668
114CAMK1G0.35809949
115ATM0.35472344
116AURKA0.35080078
117CAMKK20.34710495
118ROCK10.34663504
119SCYL20.33794350
120MAPKAPK20.33670526
121CDK180.32964878
122TSSK60.31944700
123PRKACA0.31819266
124PAK10.31506459
125MAP3K40.29601577
126PRKCD0.29529776
127EPHB10.28793551
128IRAK10.28577484
129CDK60.28522198
130FGFR20.28346958
131PRKG10.27974094
132IKBKB0.27340511
133CDK150.25583652
134ZAP700.25130800
135PRKCA0.23914727
136ERBB30.23639523
137CDK11A0.23431921
138MINK10.23230683
139UHMK10.23203932
140PIM10.23111171
141PRKD10.23051372
142CDK20.22875093
143ILK0.22390583
144PDPK10.22256753
145TEC0.22118666
146CDK10.22035130
147MARK20.21379628
148STK380.21142059
149CDK140.20953260
150AURKB0.20952356
151MATK0.20644879
152PAK30.20451246
153PRKCQ0.20204430
154PIK3CG0.19791328
155LMTK20.19498673
156ABL10.19450264
157CAMK2A0.19034585
158MAP2K70.18631523
159MTOR0.18603640
160BMPR20.18524163
161SGK10.18199334
162HIPK20.17778048
163PLK40.17731757
164CAMK2G0.17668186
165TGFBR10.17303598
166STK110.17281648
167SMG10.17263802
168FGR0.17213992
169CDC42BPA0.16304398

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009804.35882699
2DNA replication_Homo sapiens_hsa030304.04601674
3Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.87173430
4Chemical carcinogenesis_Homo sapiens_hsa052043.83581118
5Histidine metabolism_Homo sapiens_hsa003403.73950443
6Phenylalanine metabolism_Homo sapiens_hsa003603.71005433
7Base excision repair_Homo sapiens_hsa034103.33241197
8Vitamin B6 metabolism_Homo sapiens_hsa007503.18711138
9Tyrosine metabolism_Homo sapiens_hsa003502.99246551
10Fanconi anemia pathway_Homo sapiens_hsa034602.98099107
11Primary immunodeficiency_Homo sapiens_hsa053402.81242837
12beta-Alanine metabolism_Homo sapiens_hsa004102.74880584
13Mismatch repair_Homo sapiens_hsa034302.53350591
14Sphingolipid metabolism_Homo sapiens_hsa006002.36037466
15B cell receptor signaling pathway_Homo sapiens_hsa046622.14100056
16Retinol metabolism_Homo sapiens_hsa008302.10408911
17Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.03981197
18Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.00654817
19Cell cycle_Homo sapiens_hsa041101.97293098
20Huntingtons disease_Homo sapiens_hsa050161.90239075
21Pentose phosphate pathway_Homo sapiens_hsa000301.88846994
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.87810189
23Nucleotide excision repair_Homo sapiens_hsa034201.86807619
24Phototransduction_Homo sapiens_hsa047441.86696193
25Olfactory transduction_Homo sapiens_hsa047401.84248046
26Oocyte meiosis_Homo sapiens_hsa041141.84153630
27Homologous recombination_Homo sapiens_hsa034401.80907448
28Purine metabolism_Homo sapiens_hsa002301.77447414
29Propanoate metabolism_Homo sapiens_hsa006401.76865964
30Non-homologous end-joining_Homo sapiens_hsa034501.76838059
31Pyrimidine metabolism_Homo sapiens_hsa002401.73531582
32Caffeine metabolism_Homo sapiens_hsa002321.73294089
33Glucagon signaling pathway_Homo sapiens_hsa049221.72921441
34Fatty acid biosynthesis_Homo sapiens_hsa000611.72106019
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.67981866
36Nitrogen metabolism_Homo sapiens_hsa009101.67963732
37Carbohydrate digestion and absorption_Homo sapiens_hsa049731.67940574
38Pyruvate metabolism_Homo sapiens_hsa006201.65058626
39Antigen processing and presentation_Homo sapiens_hsa046121.57824668
40Dorso-ventral axis formation_Homo sapiens_hsa043201.48680434
41Glycosaminoglycan degradation_Homo sapiens_hsa005311.44429620
42Arachidonic acid metabolism_Homo sapiens_hsa005901.43659445
43Gastric acid secretion_Homo sapiens_hsa049711.40781135
44Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.37922105
45Amphetamine addiction_Homo sapiens_hsa050311.32328766
46Fatty acid degradation_Homo sapiens_hsa000711.27330829
47Spliceosome_Homo sapiens_hsa030401.22889257
48Renin-angiotensin system_Homo sapiens_hsa046141.22719024
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.22260127
50Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.21861920
51Estrogen signaling pathway_Homo sapiens_hsa049151.20879709
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.17539567
53Taste transduction_Homo sapiens_hsa047421.17053813
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.14627538
55Basal transcription factors_Homo sapiens_hsa030221.12904545
56Peroxisome_Homo sapiens_hsa041461.12502324
57Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.10642601
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.10639014
59Primary bile acid biosynthesis_Homo sapiens_hsa001201.10562022
60Inositol phosphate metabolism_Homo sapiens_hsa005621.08943544
61Selenocompound metabolism_Homo sapiens_hsa004501.07750600
62RNA transport_Homo sapiens_hsa030131.06513208
63mRNA surveillance pathway_Homo sapiens_hsa030151.05519667
64Phosphatidylinositol signaling system_Homo sapiens_hsa040701.01746226
65Collecting duct acid secretion_Homo sapiens_hsa049661.01142929
66Starch and sucrose metabolism_Homo sapiens_hsa005000.99350866
67Butanoate metabolism_Homo sapiens_hsa006500.98601892
68Glycerolipid metabolism_Homo sapiens_hsa005610.96303435
69Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.93538667
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91420730
71HTLV-I infection_Homo sapiens_hsa051660.87851690
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84807753
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83794220
74Mineral absorption_Homo sapiens_hsa049780.83637026
75Nicotine addiction_Homo sapiens_hsa050330.83608229
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.82967021
77Renin secretion_Homo sapiens_hsa049240.82593487
78Tryptophan metabolism_Homo sapiens_hsa003800.82504915
79Hedgehog signaling pathway_Homo sapiens_hsa043400.79402941
80Serotonergic synapse_Homo sapiens_hsa047260.78290560
81Hematopoietic cell lineage_Homo sapiens_hsa046400.77166852
82Thyroid hormone signaling pathway_Homo sapiens_hsa049190.76287033
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75897664
84Circadian rhythm_Homo sapiens_hsa047100.75542142
85Tight junction_Homo sapiens_hsa045300.75142452
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.74171071
87Systemic lupus erythematosus_Homo sapiens_hsa053220.72731039
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.71802965
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70149624
90Gap junction_Homo sapiens_hsa045400.69429710
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69339323
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69138646
93Glutathione metabolism_Homo sapiens_hsa004800.68970532
94Salivary secretion_Homo sapiens_hsa049700.68916951
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.66156329
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.64569585
97Complement and coagulation cascades_Homo sapiens_hsa046100.64471843
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64236870
99PPAR signaling pathway_Homo sapiens_hsa033200.64138487
100Ether lipid metabolism_Homo sapiens_hsa005650.62201065
101Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61921327
102Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60773634
103Platelet activation_Homo sapiens_hsa046110.60487151
104Calcium signaling pathway_Homo sapiens_hsa040200.58569938
105Thyroid hormone synthesis_Homo sapiens_hsa049180.55655246
106Drug metabolism - other enzymes_Homo sapiens_hsa009830.55137990
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.54178211
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.53795809
109Arginine and proline metabolism_Homo sapiens_hsa003300.53676880
110Long-term potentiation_Homo sapiens_hsa047200.53078123
111Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53002479
112Alcoholism_Homo sapiens_hsa050340.52680823
113Carbon metabolism_Homo sapiens_hsa012000.49381172
114Linoleic acid metabolism_Homo sapiens_hsa005910.49232476
115Viral carcinogenesis_Homo sapiens_hsa052030.48962138
116Ovarian steroidogenesis_Homo sapiens_hsa049130.48300804
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.47686531
118Aldosterone synthesis and secretion_Homo sapiens_hsa049250.46035159
119Circadian entrainment_Homo sapiens_hsa047130.46011995
120cAMP signaling pathway_Homo sapiens_hsa040240.45754812
121VEGF signaling pathway_Homo sapiens_hsa043700.45681274
122N-Glycan biosynthesis_Homo sapiens_hsa005100.44553984
123Pancreatic secretion_Homo sapiens_hsa049720.44344600
124Choline metabolism in cancer_Homo sapiens_hsa052310.43936025
125Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.43787433
126Epstein-Barr virus infection_Homo sapiens_hsa051690.43766792
127Measles_Homo sapiens_hsa051620.43601638
128RNA degradation_Homo sapiens_hsa030180.43198378
129Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42848943
130Vascular smooth muscle contraction_Homo sapiens_hsa042700.42819485
131Endocytosis_Homo sapiens_hsa041440.41526764
132Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.41325533
133Metabolic pathways_Homo sapiens_hsa011000.41244551
134Cysteine and methionine metabolism_Homo sapiens_hsa002700.40417472
135Glioma_Homo sapiens_hsa052140.40381846
136Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38974160
137Bile secretion_Homo sapiens_hsa049760.38276705
138Regulation of autophagy_Homo sapiens_hsa041400.38160778
139Insulin secretion_Homo sapiens_hsa049110.38064323
140Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37193576
141ECM-receptor interaction_Homo sapiens_hsa045120.36861052
142Morphine addiction_Homo sapiens_hsa050320.36776842
143Osteoclast differentiation_Homo sapiens_hsa043800.36263221
144Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34108679
145AMPK signaling pathway_Homo sapiens_hsa041520.33974682
146Vitamin digestion and absorption_Homo sapiens_hsa049770.33571025
147Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.31691345
148Chronic myeloid leukemia_Homo sapiens_hsa052200.30901549
149ABC transporters_Homo sapiens_hsa020100.29713864
150Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.29433552
151Jak-STAT signaling pathway_Homo sapiens_hsa046300.29023788
152Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29012391
153Cardiac muscle contraction_Homo sapiens_hsa042600.28336591
154Non-small cell lung cancer_Homo sapiens_hsa052230.27858161
155Sphingolipid signaling pathway_Homo sapiens_hsa040710.27590281
156Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.27494187
157Wnt signaling pathway_Homo sapiens_hsa043100.27463220
158Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27096134
159Lysine degradation_Homo sapiens_hsa003100.26485433
160Phagosome_Homo sapiens_hsa041450.25861774
161Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.24575020
162GABAergic synapse_Homo sapiens_hsa047270.22247060
163Adherens junction_Homo sapiens_hsa045200.21825197
164Glutamatergic synapse_Homo sapiens_hsa047240.20011429
165Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.19471646

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