DSEL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)4.55310991
2endocardial cushion development (GO:0003197)4.27749324
3axon extension involved in axon guidance (GO:0048846)4.02779184
4neuron projection extension involved in neuron projection guidance (GO:1902284)4.02779184
5protein heterotrimerization (GO:0070208)3.95327965
6chondrocyte proliferation (GO:0035988)3.94254078
7anterior/posterior axis specification, embryo (GO:0008595)3.87819657
8positive regulation of action potential (GO:0045760)3.74643057
9lymphangiogenesis (GO:0001946)3.71316043
10cell migration involved in heart development (GO:0060973)3.65046891
11sequestering of extracellular ligand from receptor (GO:0035581)3.58736457
12negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)3.56970506
13cell migration involved in sprouting angiogenesis (GO:0002042)3.47813859
14negative regulation of nitric-oxide synthase activity (GO:0051001)3.44592177
15metanephric mesenchyme development (GO:0072075)3.43469400
16axonal fasciculation (GO:0007413)3.35814701
17chondrocyte development (GO:0002063)3.29493597
18pericardium development (GO:0060039)3.26420369
19insulin-like growth factor receptor signaling pathway (GO:0048009)3.24797591
20mesenchymal-epithelial cell signaling (GO:0060638)3.23347616
21kidney mesenchyme development (GO:0072074)3.21507699
22axon extension (GO:0048675)3.21312687
23bone trabecula formation (GO:0060346)3.20315169
24extracellular fibril organization (GO:0043206)3.17410401
25synaptic vesicle maturation (GO:0016188)3.15426391
26regulation of hippo signaling (GO:0035330)3.10409277
27positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01368446
28dendritic spine morphogenesis (GO:0060997)2.99506807
29negative regulation of synaptic transmission, GABAergic (GO:0032229)2.96364004
30inner ear receptor cell development (GO:0060119)2.95809882
31smooth muscle tissue development (GO:0048745)2.95364917
32regulation of axon extension involved in axon guidance (GO:0048841)2.94676124
33heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.93087521
34regulation of axon guidance (GO:1902667)2.90847578
35presynaptic membrane assembly (GO:0097105)2.88868937
36negative regulation of catenin import into nucleus (GO:0035414)2.86736498
37negative chemotaxis (GO:0050919)2.86150692
38* dermatan sulfate metabolic process (GO:0030205)2.85502166
39negative regulation of protein localization to cell surface (GO:2000009)2.82535911
40camera-type eye morphogenesis (GO:0048593)2.82226624
41collagen catabolic process (GO:0030574)2.79484097
42negative regulation of BMP signaling pathway (GO:0030514)2.79423782
43collagen metabolic process (GO:0032963)2.79345814
44dendrite morphogenesis (GO:0048813)2.79197609
45positive regulation of cardiac muscle cell differentiation (GO:2000727)2.78960257
46regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.78215144
47positive regulation of protein autophosphorylation (GO:0031954)2.77918064
48neuron recognition (GO:0008038)2.76905532
49layer formation in cerebral cortex (GO:0021819)2.75934676
50hippo signaling (GO:0035329)2.75446868
51regulation of integrin-mediated signaling pathway (GO:2001044)2.75441729
52negative regulation of cardiac muscle tissue development (GO:0055026)2.75374343
53negative regulation of axon extension involved in axon guidance (GO:0048843)2.74808691
54negative regulation of chondrocyte differentiation (GO:0032331)2.73819562
55endothelial cell morphogenesis (GO:0001886)2.73243100
56regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.72586508
57negative regulation of axon guidance (GO:1902668)2.72504109
58regulation of action potential (GO:0098900)2.72007845
59neuron projection extension (GO:1990138)2.71170266
60regulation of organ formation (GO:0003156)2.69170372
61activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.66609615
62regulation of mesoderm development (GO:2000380)2.65913859
63craniofacial suture morphogenesis (GO:0097094)2.65484363
64multicellular organismal macromolecule metabolic process (GO:0044259)2.65079122
65tachykinin receptor signaling pathway (GO:0007217)2.64809747
66endodermal cell differentiation (GO:0035987)2.63201936
67membrane assembly (GO:0071709)2.61992083
68type B pancreatic cell proliferation (GO:0044342)2.60759690
69embryonic forelimb morphogenesis (GO:0035115)2.58808077
70substrate-dependent cell migration (GO:0006929)2.56885770
71ventricular septum development (GO:0003281)2.55089789
72regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.54376735
73planar cell polarity pathway involved in neural tube closure (GO:0090179)2.54366091
74SMAD protein complex assembly (GO:0007183)2.52616473
75negative regulation of embryonic development (GO:0045992)2.52426923
76multicellular organismal catabolic process (GO:0044243)2.52379552
77regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.51612487
78cellular response to vitamin (GO:0071295)2.51303014
79establishment or maintenance of monopolar cell polarity (GO:0061339)2.51207024
80establishment of monopolar cell polarity (GO:0061162)2.51207024
81establishment of nucleus localization (GO:0040023)2.50964759
82regulation of cardiac muscle cell differentiation (GO:2000725)2.50572153
83cell adhesion mediated by integrin (GO:0033627)2.50132577
84regulation of short-term neuronal synaptic plasticity (GO:0048172)2.49744733
85multicellular organismal metabolic process (GO:0044236)2.47979962
86neural crest cell development (GO:0014032)2.47297872
87fibril organization (GO:0097435)2.47126566
88positive regulation of catecholamine secretion (GO:0033605)2.46574075
89outer ear morphogenesis (GO:0042473)2.45511959
90forelimb morphogenesis (GO:0035136)2.45450124
91central nervous system projection neuron axonogenesis (GO:0021952)2.44698449
92positive regulation of fibroblast migration (GO:0010763)2.42068392
93branching involved in prostate gland morphogenesis (GO:0060442)2.41768843
94extracellular matrix assembly (GO:0085029)2.41543225
95regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.41305537
96protein localization to cell surface (GO:0034394)2.41005922
97postsynaptic membrane organization (GO:0001941)2.40831163
98presynaptic membrane organization (GO:0097090)2.40178109
99positive regulation of steroid hormone secretion (GO:2000833)2.38896178
100response to gravity (GO:0009629)2.38726701
101face morphogenesis (GO:0060325)2.37810735
102cell proliferation involved in metanephros development (GO:0072203)2.37602569
103positive regulation of male gonad development (GO:2000020)2.36961493
104peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.36832852
105negative regulation of mast cell activation (GO:0033004)2.35977487
106locomotory exploration behavior (GO:0035641)2.35270239
107head development (GO:0060322)2.34612584
108regulation of mesenchymal cell proliferation (GO:0010464)2.34327561
109positive regulation of cartilage development (GO:0061036)2.34123131
110substrate adhesion-dependent cell spreading (GO:0034446)2.33591778
111positive regulation of axon extension (GO:0045773)2.32674802
112positive regulation of mesenchymal cell proliferation (GO:0002053)2.32639100
113negative regulation of JAK-STAT cascade (GO:0046426)2.32358175
114exploration behavior (GO:0035640)2.32168761
115G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.30551222
116cell proliferation involved in kidney development (GO:0072111)2.30545848
117plasma membrane repair (GO:0001778)2.29408465
118positive regulation of synapse assembly (GO:0051965)2.29249843
119innervation (GO:0060384)2.27997333
120gonadal mesoderm development (GO:0007506)2.27746047
121fibroblast migration (GO:0010761)2.27248288
122positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.27030375
123negative regulation of fatty acid transport (GO:2000192)2.26137046
124dendrite development (GO:0016358)2.25844453
125retina vasculature morphogenesis in camera-type eye (GO:0061299)2.23427456
126synaptic vesicle exocytosis (GO:0016079)2.23361184
127polarized epithelial cell differentiation (GO:0030859)2.23149405
128startle response (GO:0001964)2.22468310
129regulation of long-term neuronal synaptic plasticity (GO:0048169)2.22105861
130regulation of neuron migration (GO:2001222)2.22080148
131paraxial mesoderm development (GO:0048339)2.22010780
132protein localization to synapse (GO:0035418)2.21917786
133extracellular matrix disassembly (GO:0022617)2.21814694
134regulation of BMP signaling pathway (GO:0030510)2.21792533
135dendritic spine organization (GO:0097061)2.20049206
136* dermatan sulfate biosynthetic process (GO:0030208)2.19976003
137developmental cell growth (GO:0048588)2.19781031
138sprouting angiogenesis (GO:0002040)2.19436623
139glial cell migration (GO:0008347)2.18838581
140neuronal ion channel clustering (GO:0045161)2.18663987
141negative regulation of activin receptor signaling pathway (GO:0032926)2.18038679
142body morphogenesis (GO:0010171)2.17979675
143embryonic cranial skeleton morphogenesis (GO:0048701)2.17525382
144regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.17351294
145positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.17312737
146vascular endothelial growth factor signaling pathway (GO:0038084)2.16239355
147heparan sulfate proteoglycan metabolic process (GO:0030201)2.15677457
148artery development (GO:0060840)2.15481983
149skin morphogenesis (GO:0043589)2.15097130
150glomerular filtration (GO:0003094)2.13962701
151anatomical structure arrangement (GO:0048532)2.13704427
152negative regulation of cartilage development (GO:0061037)2.11690159
153extracellular regulation of signal transduction (GO:1900115)2.11462162
154extracellular negative regulation of signal transduction (GO:1900116)2.11462162
155cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.11401789
156ganglion development (GO:0061548)2.09893360
157regulation of synapse structural plasticity (GO:0051823)2.09397189
158clathrin coat assembly (GO:0048268)2.09080094
159glomerular basement membrane development (GO:0032836)2.08909363
160middle ear morphogenesis (GO:0042474)2.08894918
161renal filtration (GO:0097205)2.07165256
162negative regulation of axon extension (GO:0030517)2.06311806
163embryonic skeletal joint morphogenesis (GO:0060272)2.06143711

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.12913350
2TRIM28_21343339_ChIP-Seq_HEK293_Human3.09456343
3GBX2_23144817_ChIP-Seq_PC3_Human2.70157880
4EZH2_22144423_ChIP-Seq_EOC_Human2.63128239
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.46505023
6* CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.45125548
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40627833
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40627833
9EED_16625203_ChIP-ChIP_MESCs_Mouse2.35924619
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.26250032
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.26226796
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.23647206
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.19565380
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.16227732
15TP63_17297297_ChIP-ChIP_HaCaT_Human2.12845444
16WT1_19549856_ChIP-ChIP_CCG9911_Human2.08487797
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.04370535
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.00539018
19CDX2_19796622_ChIP-Seq_MESCs_Mouse1.99256049
20RNF2_27304074_Chip-Seq_ESCs_Mouse1.94687306
21AR_21572438_ChIP-Seq_LNCaP_Human1.92051618
22ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.89938883
23ZNF217_24962896_ChIP-Seq_MCF-7_Human1.86520943
24RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.86121664
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.84426581
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.81518164
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.80174702
28SALL1_21062744_ChIP-ChIP_HESCs_Human1.78315152
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.76703246
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.76263431
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.74784152
32TP53_18474530_ChIP-ChIP_U2OS_Human1.69003375
33TP53_16413492_ChIP-PET_HCT116_Human1.68960202
34TAF15_26573619_Chip-Seq_HEK293_Human1.68420279
35* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.67280331
36TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.66032742
37PIAS1_25552417_ChIP-Seq_VCAP_Human1.63122140
38SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.60621754
39OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.58374524
40SMAD4_21799915_ChIP-Seq_A2780_Human1.56527925
41* P300_19829295_ChIP-Seq_ESCs_Human1.56135461
42* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.54250575
43POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53942364
44* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.53166836
45NRF2_20460467_ChIP-Seq_MEFs_Mouse1.52902681
46NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.52902681
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.52250432
48* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.52183028
49* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51728048
50BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.51416823
51EZH2_27294783_Chip-Seq_ESCs_Mouse1.50148983
52FUS_26573619_Chip-Seq_HEK293_Human1.49867543
53ARNT_22903824_ChIP-Seq_MCF-7_Human1.49716693
54EP300_21415370_ChIP-Seq_HL-1_Mouse1.49589767
55SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.47829307
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.46690477
57RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44607645
58* CJUN_26792858_Chip-Seq_BT549_Human1.44046014
59AHR_22903824_ChIP-Seq_MCF-7_Human1.43065430
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42827710
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41320114
62ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40818373
63ZNF274_21170338_ChIP-Seq_K562_Hela1.39484282
64* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.38456598
65DROSHA_22980978_ChIP-Seq_HELA_Human1.38357251
66EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.34604190
67* PCGF2_27294783_Chip-Seq_NPCs_Mouse1.32305032
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31888295
69* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.31052947
70VDR_22108803_ChIP-Seq_LS180_Human1.30095474
71* EZH2_27294783_Chip-Seq_NPCs_Mouse1.29853995
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.29551342
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28519851
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.26795597
75* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.26748721
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.25877256
77* NANOG_18555785_Chip-Seq_ESCs_Mouse1.25587230
78POU5F1_16153702_ChIP-ChIP_HESCs_Human1.24176740
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.23338265
80SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22572865
81* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21386841
82AR_25329375_ChIP-Seq_VCAP_Human1.20776462
83* KDM2B_26808549_Chip-Seq_REH_Human1.20754445
84* RING1B_27294783_Chip-Seq_NPCs_Mouse1.19671926
85TCF4_23295773_ChIP-Seq_U87_Human1.19536601
86SOX2_21211035_ChIP-Seq_LN229_Gbm1.18648567
87TBX3_20139965_ChIP-Seq_ESCs_Mouse1.18418869
88CBP_20019798_ChIP-Seq_JUKART_Human1.17623896
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17623896
90EWS_26573619_Chip-Seq_HEK293_Human1.17386821
91TBX3_20139965_ChIP-Seq_MESCs_Mouse1.17386588
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17313620
93TP53_20018659_ChIP-ChIP_R1E_Mouse1.17301378
94RXR_22108803_ChIP-Seq_LS180_Human1.17184000
95WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17058710
96HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.14721385
97FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14609701
98BRD4_25478319_ChIP-Seq_HGPS_Human1.14514617
99* SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.13213012
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12284598
101* RING1B_27294783_Chip-Seq_ESCs_Mouse1.12203887
102TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.11910390
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11860226
104* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.10511920
105* P53_22387025_ChIP-Seq_ESCs_Mouse1.10212457
106FLI1_21867929_ChIP-Seq_TH2_Mouse1.09891134
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09146033
108SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.08254619
109* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08223902
110CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07818127
111ER_23166858_ChIP-Seq_MCF-7_Human1.07688742
112RUNX2_22187159_ChIP-Seq_PCA_Human1.07567940
113BCAT_22108803_ChIP-Seq_LS180_Human1.07473924
114* NFE2_27457419_Chip-Seq_LIVER_Mouse1.07124651
115PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05618717
116RARG_19884340_ChIP-ChIP_MEFs_Mouse1.04869835
117* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04806160
118TCF4_18268006_ChIP-ChIP_LS174T_Human1.00805626
119STAT3_23295773_ChIP-Seq_U87_Human1.00726274
120CLOCK_20551151_ChIP-Seq_293T_Human1.00151584
121IGF1R_20145208_ChIP-Seq_DFB_Human0.99046392
122* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98996549
123* RNF2_27304074_Chip-Seq_NSC_Mouse0.98941384
124ISL1_27105846_Chip-Seq_CPCs_Mouse0.97345832
125NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96514294
126AR_19668381_ChIP-Seq_PC3_Human0.95477820
127JUN_21703547_ChIP-Seq_K562_Human0.94683243
128HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93698938
129SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93584277

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.19992789
2MP0005275_abnormal_skin_tensile4.32214181
3MP0005503_abnormal_tendon_morphology4.30773332
4MP0010386_abnormal_urinary_bladder3.46622769
5MP0000569_abnormal_digit_pigmentation2.76278205
6MP0003705_abnormal_hypodermis_morpholog2.73429844
7MP0004272_abnormal_basement_membrane2.71973237
8MP0003279_aneurysm2.36806714
9MP0005623_abnormal_meninges_morphology2.36325872
10MP0004859_abnormal_synaptic_plasticity2.12484620
11MP0002102_abnormal_ear_morphology2.06606415
12MP0001958_emphysema1.95121798
13MP0005171_absent_coat_pigmentation1.94736958
14MP0001299_abnormal_eye_distance/1.91951988
15MP0009250_abnormal_appendicular_skeleto1.90464509
16MP0003385_abnormal_body_wall1.85362546
17MP0009053_abnormal_anal_canal1.70826838
18MP0005508_abnormal_skeleton_morphology1.69548969
19MP0003950_abnormal_plasma_membrane1.69214542
20MP0006054_spinal_hemorrhage1.65888704
21MP0000537_abnormal_urethra_morphology1.62814526
22MP0003122_maternal_imprinting1.59831161
23MP0002108_abnormal_muscle_morphology1.57089371
24MP0009384_cardiac_valve_regurgitation1.56019835
25MP0009780_abnormal_chondrocyte_physiolo1.55312233
26MP0000534_abnormal_ureter_morphology1.54380018
27MP0000538_abnormal_urinary_bladder1.51892642
28MP0003942_abnormal_urinary_system1.46286517
29MP0005595_abnormal_vascular_smooth1.44104301
30MP0010234_abnormal_vibrissa_follicle1.41459270
31MP0000751_myopathy1.41225859
32MP0003283_abnormal_digestive_organ1.40358145
33MP0000516_abnormal_urinary_system1.39887892
34MP0005367_renal/urinary_system_phenotyp1.39887892
35MP0002233_abnormal_nose_morphology1.38114365
36MP0000778_abnormal_nervous_system1.37555753
37MP0002896_abnormal_bone_mineralization1.37516121
38MP0008789_abnormal_olfactory_epithelium1.31689096
39MP0002060_abnormal_skin_morphology1.31165687
40MP0002282_abnormal_trachea_morphology1.29672737
41MP0005257_abnormal_intraocular_pressure1.28163481
42MP0003755_abnormal_palate_morphology1.26856498
43MP0003091_abnormal_cell_migration1.26068971
44MP0005187_abnormal_penis_morphology1.25186003
45MP0000428_abnormal_craniofacial_morphol1.22782304
46MP0004133_heterotaxia1.22120230
47MP0003635_abnormal_synaptic_transmissio1.22104489
48MP0005394_taste/olfaction_phenotype1.20764564
49MP0005499_abnormal_olfactory_system1.20764564
50MP0002736_abnormal_nociception_after1.18026986
51MP0010030_abnormal_orbit_morphology1.15391524
52MP0001177_atelectasis1.14752740
53MP0003941_abnormal_skin_development1.14674686
54MP0002295_abnormal_pulmonary_circulatio1.14544668
55MP0002177_abnormal_outer_ear1.13271445
56MP0000049_abnormal_middle_ear1.09986149
57MP0004270_analgesia1.09430961
58MP0003937_abnormal_limbs/digits/tail_de1.08131162
59MP0006072_abnormal_retinal_apoptosis1.07323155
60MP0000013_abnormal_adipose_tissue1.05285599
61MP0000733_abnormal_muscle_development1.04862612
62MP0004134_abnormal_chest_morphology1.03733561
63MP0001968_abnormal_touch/_nociception1.02805200
64MP0002160_abnormal_reproductive_system1.02620448
65MP0002184_abnormal_innervation1.02308281
66MP0000427_abnormal_hair_cycle1.01608984
67MP0002234_abnormal_pharynx_morphology0.99666247
68MP0002938_white_spotting0.99564544
69MP0002115_abnormal_skeleton_extremities0.99334579
70MP0003566_abnormal_cell_adhesion0.97608056
71MP0002116_abnormal_craniofacial_bone0.96715051
72MP0000762_abnormal_tongue_morphology0.96698540
73MP0002063_abnormal_learning/memory/cond0.95037711
74MP0003123_paternal_imprinting0.94301417
75MP0001243_abnormal_dermal_layer0.93987800
76MP0002932_abnormal_joint_morphology0.93490064
77MP0003935_abnormal_craniofacial_develop0.92857382
78MP0002109_abnormal_limb_morphology0.92039466
79MP0003121_genomic_imprinting0.90481627
80MP0002735_abnormal_chemical_nociception0.89791445
81MP0000163_abnormal_cartilage_morphology0.87147260
82MP0002751_abnormal_autonomic_nervous0.86178818
83MP0001529_abnormal_vocalization0.83986707
84MP0001340_abnormal_eyelid_morphology0.83635928
85MP0005248_abnormal_Harderian_gland0.83565083
86MP0003880_abnormal_central_pattern0.83506762
87MP0004858_abnormal_nervous_system0.83273837
88MP0000749_muscle_degeneration0.83183149
89MP0000767_abnormal_smooth_muscle0.81427856
90MP0002272_abnormal_nervous_system0.81370875
91MP0010368_abnormal_lymphatic_system0.80674851
92MP0001486_abnormal_startle_reflex0.80070764
93MP0003119_abnormal_digestive_system0.79626005
94MP0004145_abnormal_muscle_electrophysio0.77805731
95MP0005076_abnormal_cell_differentiation0.77659442
96MP0009379_abnormal_foot_pigmentation0.77167201
97MP0005551_abnormal_eye_electrophysiolog0.76889622
98MP0001879_abnormal_lymphatic_vessel0.76406645
99MP0000432_abnormal_head_morphology0.75150334
100MP0004885_abnormal_endolymph0.74758929
101MP0003115_abnormal_respiratory_system0.73321794
102MP0002133_abnormal_respiratory_system0.73313881
103MP0005388_respiratory_system_phenotype0.73313881
104MP0000230_abnormal_systemic_arterial0.72146676
105MP0002113_abnormal_skeleton_development0.72120389
106MP0002734_abnormal_mechanical_nocicepti0.71705735
107MP0005023_abnormal_wound_healing0.71276514
108MP0000631_abnormal_neuroendocrine_gland0.70711426
109MP0001542_abnormal_bone_strength0.70273891
110MP0009745_abnormal_behavioral_response0.70168286
111MP0002114_abnormal_axial_skeleton0.69368163
112MP0002168_other_aberrant_phenotype0.69011063
113MP0001849_ear_inflammation0.68956743
114MP0001348_abnormal_lacrimal_gland0.68450368
115MP0004084_abnormal_cardiac_muscle0.68347035
116MP0002877_abnormal_melanocyte_morpholog0.67878607
117MP0010352_gastrointestinal_tract_polyps0.67542842
118MP0000003_abnormal_adipose_tissue0.67206574
119MP0001984_abnormal_olfaction0.67098379
120MP0003045_fibrosis0.67049972
121MP0002249_abnormal_larynx_morphology0.66798417
122MP0002009_preneoplasia0.66001824
123MP0005620_abnormal_muscle_contractility0.65999189
124MP0008775_abnormal_heart_ventricle0.65662090
125MP0004811_abnormal_neuron_physiology0.65169516
126MP0004142_abnormal_muscle_tone0.64460473
127MP0005197_abnormal_uvea_morphology0.63784400
128MP0005646_abnormal_pituitary_gland0.63431975

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)5.26483950
2Premature rupture of membranes (HP:0001788)5.20187771
3Shallow orbits (HP:0000586)3.86041469
4Atrophic scars (HP:0001075)3.78152732
5Aortic dissection (HP:0002647)3.67932524
6Follicular hyperkeratosis (HP:0007502)3.66042586
7Broad metatarsal (HP:0001783)3.57443103
8Soft skin (HP:0000977)3.51029099
9Ankle contracture (HP:0006466)3.49088988
10Bladder diverticulum (HP:0000015)3.17540022
11Abnormality of dentin (HP:0010299)3.16355438
12Aplasia of the musculature (HP:0100854)3.13042472
13Fragile skin (HP:0001030)3.05754055
14Dilatation of the ascending aorta (HP:0005111)3.03880658
15Neonatal short-limb short stature (HP:0008921)2.87343396
16Arterial tortuosity (HP:0005116)2.85751717
17Vascular tortuosity (HP:0004948)2.85285670
18Cerebral aneurysm (HP:0004944)2.84470504
19Mitral valve prolapse (HP:0001634)2.82377781
20Increased corneal curvature (HP:0100692)2.68235942
21Keratoconus (HP:0000563)2.68235942
22Aortic aneurysm (HP:0004942)2.67818660
23Peritonitis (HP:0002586)2.64757301
24Short 4th metacarpal (HP:0010044)2.63893247
25Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.63893247
26Genu recurvatum (HP:0002816)2.62109128
27Overgrowth (HP:0001548)2.60581736
28Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.57577338
29Short 1st metacarpal (HP:0010034)2.57577338
30Spondylolisthesis (HP:0003302)2.57212096
31Wrist flexion contracture (HP:0001239)2.43482665
32Wormian bones (HP:0002645)2.42495921
33Aortic regurgitation (HP:0001659)2.39897557
34Buphthalmos (HP:0000557)2.38095873
35Slender build (HP:0001533)2.36929804
36Broad ribs (HP:0000885)2.35471829
37Type 1 muscle fiber predominance (HP:0003803)2.32049745
38Spinal rigidity (HP:0003306)2.31113868
39Short hallux (HP:0010109)2.28573157
40Hyperextensible skin (HP:0000974)2.27383978
41Increased number of teeth (HP:0011069)2.26946528
42Blue sclerae (HP:0000592)2.26031117
43Hypoventilation (HP:0002791)2.22382266
44Coronal craniosynostosis (HP:0004440)2.20995280
45Spinal cord lesions (HP:0100561)2.17404660
46Syringomyelia (HP:0003396)2.17404660
47Abnormality of the 1st metacarpal (HP:0010009)2.15801987
48Aplasia/Hypoplasia of the hallux (HP:0008362)2.13854135
49Bowel diverticulosis (HP:0005222)2.13647630
50Aplasia/Hypoplasia involving the musculature (HP:0001460)2.11787388
51Asymmetry of the thorax (HP:0001555)2.09588612
52Striae distensae (HP:0001065)2.06919677
53Infantile muscular hypotonia (HP:0008947)2.06365223
54Cardiovascular calcification (HP:0011915)2.05014944
55Delayed gross motor development (HP:0002194)2.03215957
56Joint laxity (HP:0001388)2.03006256
57Narrow nasal bridge (HP:0000446)1.99314489
58Bell-shaped thorax (HP:0001591)1.98941626
59Limited hip movement (HP:0008800)1.98634102
60Bronchomalacia (HP:0002780)1.97895676
61Increased variability in muscle fiber diameter (HP:0003557)1.96924036
62Subacute progressive viral hepatitis (HP:0006572)1.96692315
63Abnormality of the 4th metacarpal (HP:0010012)1.96303167
64Insidious onset (HP:0003587)1.95977057
65Termporal pattern (HP:0011008)1.95977057
66Abnormality of the ischium (HP:0003174)1.94989331
67Abnormality of the 2nd finger (HP:0004100)1.93913138
68Ulnar claw (HP:0001178)1.93434968
69Morphological abnormality of the middle ear (HP:0008609)1.93344858
70Hyperventilation (HP:0002883)1.93147254
71Chorioretinal atrophy (HP:0000533)1.92403996
72Abnormality of the phalanges of the 2nd finger (HP:0009541)1.90994587
73Aortic valve stenosis (HP:0001650)1.89975993
74Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.89201259
75Mild short stature (HP:0003502)1.88957397
76Absent frontal sinuses (HP:0002688)1.87969942
77Cervical subluxation (HP:0003308)1.87116689
78Deviation of the hallux (HP:0010051)1.86135863
79Small hand (HP:0200055)1.85886484
80Synostosis of carpal bones (HP:0005048)1.85098763
81Entropion (HP:0000621)1.84501122
82Bulbous nose (HP:0000414)1.84212211
83Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.83954685
84Knee flexion contracture (HP:0006380)1.83436754
85Abnormality of the frontal sinuses (HP:0002687)1.82455535
86Aplasia involving bones of the upper limbs (HP:0009823)1.82365991
87Aplasia of the phalanges of the hand (HP:0009802)1.82365991
88Aplasia involving bones of the extremities (HP:0009825)1.82365991
89Protruding ear (HP:0000411)1.80776598
90Microglossia (HP:0000171)1.79925344
91Aplasia/Hypoplasia of the tibia (HP:0005772)1.78358510
92Wide anterior fontanel (HP:0000260)1.76060387
93Venous insufficiency (HP:0005293)1.75012642
94Fibular hypoplasia (HP:0003038)1.74290810
95Tarsal synostosis (HP:0008368)1.73595783
96Mildly elevated creatine phosphokinase (HP:0008180)1.73561342
97Cutaneous finger syndactyly (HP:0010554)1.71628883
98Spinal cord compression (HP:0002176)1.71436525
99Action tremor (HP:0002345)1.71084270
100Hallux valgus (HP:0001822)1.70932611
101Synostosis involving bones of the feet (HP:0009140)1.70911149
102Synostosis involving bones of the lower limbs (HP:0009138)1.70911149
103Broad long bones (HP:0005622)1.70599396
104Ankyloglossia (HP:0010296)1.70190096
105Venous abnormality (HP:0002624)1.69912409
106Bradycardia (HP:0001662)1.69495665
107Flat cornea (HP:0007720)1.69488660
108Mesomelia (HP:0003027)1.69387072
109Alopecia of scalp (HP:0002293)1.68963448
110Decreased muscle mass (HP:0003199)1.68673396
111Hepatoblastoma (HP:0002884)1.68433662
112Abnormality of the nasal septum (HP:0000419)1.67867177
113Mitral stenosis (HP:0001718)1.67712371
114Lower limb amyotrophy (HP:0007210)1.67699779
115Limb-girdle muscle weakness (HP:0003325)1.67599971
116Redundant skin (HP:0001582)1.66774162
117Abnormality of the middle phalanges of the toes (HP:0010183)1.66539105
118Radial bowing (HP:0002986)1.65893590
119Abnormality of the phalanges of the 5th finger (HP:0004213)1.64214885
120Elbow flexion contracture (HP:0002987)1.64161500
121Scapular winging (HP:0003691)1.64025145
122Hypoplasia of the maxilla (HP:0000327)1.63306211
123Aplasia/Hypoplasia of the fibula (HP:0006492)1.62314999
124Osteoarthritis (HP:0002758)1.62134122
125Genetic anticipation (HP:0003743)1.62037452
126Increased connective tissue (HP:0009025)1.61927696
127Hip contracture (HP:0003273)1.61346249
128Thin bony cortex (HP:0002753)1.60806882
129Congenital glaucoma (HP:0001087)1.60099980
130Abnormality of skeletal muscle fiber size (HP:0012084)1.60093314
131Short phalanx of the thumb (HP:0009660)1.59647259
132Abnormality of the proximal phalanges of the hand (HP:0009834)1.59405702
133Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.59353763
134Fibular aplasia (HP:0002990)1.59087079
135Mitral regurgitation (HP:0001653)1.59044117
136Pancreatic fibrosis (HP:0100732)1.58296236
137Narrow palate (HP:0000189)1.57454521
138Abnormal delivery (HP:0001787)1.57239531
139Hypoplastic labia majora (HP:0000059)1.56156327
140Abnormality of the anterior chamber (HP:0000593)1.55834694
141Papilledema (HP:0001085)1.55455474
142Ovoid vertebral bodies (HP:0003300)1.55361896
143Inguinal hernia (HP:0000023)1.55186767
144Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.54360556
145Hypoplasia of the iris (HP:0007676)1.53406489
146Hypoplastic ischia (HP:0003175)1.53381458
147Osteolytic defects of the phalanges of the hand (HP:0009771)1.52794344
148Osteolytic defects of the hand bones (HP:0009699)1.52794344
149Exotropia (HP:0000577)1.50859812
150Short nail (HP:0001799)1.48307764
151Biconcave vertebral bodies (HP:0004586)1.47199884

Predicted kinase interactions (KEA)

RankGene SetZ-score
1AKT34.91118627
2DDR23.87568533
3MYLK3.30791259
4ERBB33.24490151
5FRK3.08149361
6LATS12.84770341
7MARK12.76222621
8EPHB22.74568038
9LATS22.56563018
10NTRK12.39358446
11KSR12.30903855
12FER2.22187885
13PDGFRA2.15758378
14NTRK32.15541396
15MUSK2.15312654
16PLK22.14313332
17FGFR21.95547895
18GRK11.95111676
19ERBB41.92504700
20MINK11.91807575
21MAP3K21.88585840
22MAP3K91.81376101
23NEK91.78905694
24MAP3K41.75955329
25PRKD21.70818213
26EPHA41.62668406
27ADRBK21.57129204
28BCR1.54583986
29TTN1.53437722
30PAK31.32845142
31FLT31.32411640
32TYRO31.30819384
33WNK31.27697961
34ACVR1B1.27575094
35SCYL21.24636513
36PTK2B1.22734831
37PDGFRB1.21304879
38PAK61.20053344
39NTRK21.19716477
40SIK11.18993712
41EPHA31.18566674
42FGFR11.17031720
43PRKD31.13333275
44STK381.12773496
45KSR21.10704636
46BRSK21.09622444
47LIMK11.08070902
48RET1.07390323
49STK38L1.06471255
50PNCK1.05384530
51GRK71.04820245
52SIK31.00265601
53PIK3CA0.96805920
54PINK10.96137495
55PRKCH0.94714999
56PRKCE0.94473976
57MAP4K20.94174780
58MAPK130.93037369
59CAMKK10.92722564
60CAMKK20.90677380
61ROCK10.86244073
62CASK0.85688201
63SGK20.83532933
64CSNK1G20.83311431
65MKNK10.81673894
66STK390.81077503
67SGK4940.80608069
68SGK2230.80608069
69CDK50.79833594
70FGFR30.79826989
71TGFBR10.77967448
72PAK20.77071727
73DMPK0.76924976
74PIK3CG0.76594735
75PTK20.75525150
76MAP2K70.73038807
77MAP2K10.71396504
78SGK30.71173761
79ROCK20.69299364
80MET0.69143788
81WNK40.67729784
82CAMK2A0.66953771
83CDK140.66836519
84CSNK1G10.64969938
85CAMK1G0.64880538
86CDK180.64669053
87GSK3A0.64219145
88STK30.62478169
89CAMK1D0.62206755
90UHMK10.62015061
91CDK120.61955521
92PRKCG0.61827714
93DAPK20.61091828
94WNK10.60590236
95CSNK1A1L0.60429097
96ABL20.59499758
97ZAK0.58172278
98PIM20.58127803
99EIF2AK30.58002649
100TIE10.56819704
101TGFBR20.56687997
102TRPM70.56535269
103INSR0.54780499
104CDK150.54682944
105TNIK0.54248183
106SRC0.54029493
107GRK50.53145352
108MELK0.52719875
109NUAK10.51968918
110NEK10.51132073
111MAP3K120.51022805
112PHKG20.50639607
113PHKG10.50639607
114ABL10.50324568
115CAMK2B0.49231564
116MOS0.48666152
117STK110.48621800
118ADRBK10.47977103
119PLK30.47907381
120CSNK1G30.47702899
121MAPKAPK50.47546759
122PRKD10.47385222
123BMPR1B0.47345450
124FYN0.46528656
125PTK60.45752973
126CAMK2G0.45302076
127MAPKAPK30.44501687
128SGK10.43727560
129MAP2K40.42400343
130OXSR10.42184174
131PKN10.41249732
132ERBB20.40495785
133CAMK2D0.39508077
134CDK80.39103937
135MKNK20.38136224
136MAPK100.37977199
137MAPK80.37174870
138TLK10.36738775
139BMX0.36445509
140MST1R0.36221152
141RPS6KA20.36055707

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.37268090
2Selenocompound metabolism_Homo sapiens_hsa004501.93864581
3Axon guidance_Homo sapiens_hsa043601.88180915
4Focal adhesion_Homo sapiens_hsa045101.80860342
5Sulfur metabolism_Homo sapiens_hsa009201.68974215
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65095965
7Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.61333418
8Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.60611148
9Circadian entrainment_Homo sapiens_hsa047131.58457972
10Olfactory transduction_Homo sapiens_hsa047401.52591891
11Dilated cardiomyopathy_Homo sapiens_hsa054141.52069027
12Long-term potentiation_Homo sapiens_hsa047201.51057326
13Nicotine addiction_Homo sapiens_hsa050331.50496497
14Dopaminergic synapse_Homo sapiens_hsa047281.48919865
15Gap junction_Homo sapiens_hsa045401.48278946
16Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.47275410
17Renin secretion_Homo sapiens_hsa049241.45106546
18Amphetamine addiction_Homo sapiens_hsa050311.43695887
19Hippo signaling pathway_Homo sapiens_hsa043901.42400403
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.41457680
21Adherens junction_Homo sapiens_hsa045201.38867993
22Cholinergic synapse_Homo sapiens_hsa047251.37983763
23Glioma_Homo sapiens_hsa052141.36733336
24Proteoglycans in cancer_Homo sapiens_hsa052051.35861393
25Synaptic vesicle cycle_Homo sapiens_hsa047211.33847352
26Melanogenesis_Homo sapiens_hsa049161.33058160
27Hedgehog signaling pathway_Homo sapiens_hsa043401.31146247
28GnRH signaling pathway_Homo sapiens_hsa049121.30490257
29Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.30166590
30Basal cell carcinoma_Homo sapiens_hsa052171.29547798
31Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.27823524
32Oxytocin signaling pathway_Homo sapiens_hsa049211.27742160
33Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.27245082
34Estrogen signaling pathway_Homo sapiens_hsa049151.25998866
35Glutamatergic synapse_Homo sapiens_hsa047241.24979709
36Cocaine addiction_Homo sapiens_hsa050301.24628837
37Protein digestion and absorption_Homo sapiens_hsa049741.24362642
38Amoebiasis_Homo sapiens_hsa051461.23136379
39Phototransduction_Homo sapiens_hsa047441.22660001
40TGF-beta signaling pathway_Homo sapiens_hsa043501.21631124
41Protein export_Homo sapiens_hsa030601.19342026
42GABAergic synapse_Homo sapiens_hsa047271.18991838
43Morphine addiction_Homo sapiens_hsa050321.18613901
44Wnt signaling pathway_Homo sapiens_hsa043101.18047317
45MicroRNAs in cancer_Homo sapiens_hsa052061.17378248
46Long-term depression_Homo sapiens_hsa047301.17087875
47Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16652155
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16244550
49Gastric acid secretion_Homo sapiens_hsa049711.15714352
50Salivary secretion_Homo sapiens_hsa049701.14823060
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.13025911
52Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.11833128
53Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.11038770
54Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10920438
55ErbB signaling pathway_Homo sapiens_hsa040121.10256430
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.10250530
57Renal cell carcinoma_Homo sapiens_hsa052111.07840774
58Melanoma_Homo sapiens_hsa052181.06953827
59p53 signaling pathway_Homo sapiens_hsa041151.06423289
60Endometrial cancer_Homo sapiens_hsa052131.05854106
61Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.05486918
62Serotonergic synapse_Homo sapiens_hsa047261.04534576
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03597549
64Colorectal cancer_Homo sapiens_hsa052101.02911756
65Basal transcription factors_Homo sapiens_hsa030221.00687681
66Rap1 signaling pathway_Homo sapiens_hsa040151.00391826
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.00378404
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00258515
69PI3K-Akt signaling pathway_Homo sapiens_hsa041510.98196057
70Insulin secretion_Homo sapiens_hsa049110.96502368
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.96062170
72Tight junction_Homo sapiens_hsa045300.95909817
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.94996183
74Ras signaling pathway_Homo sapiens_hsa040140.93760108
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.92357151
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91585831
77Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90541403
78Platelet activation_Homo sapiens_hsa046110.89158952
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89071027
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87982924
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87336737
82Prostate cancer_Homo sapiens_hsa052150.87180321
83Nitrogen metabolism_Homo sapiens_hsa009100.86881423
84Chronic myeloid leukemia_Homo sapiens_hsa052200.86749090
85cAMP signaling pathway_Homo sapiens_hsa040240.86317908
86Oocyte meiosis_Homo sapiens_hsa041140.86090153
87Dorso-ventral axis formation_Homo sapiens_hsa043200.85037865
88Vibrio cholerae infection_Homo sapiens_hsa051100.84371393
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84318603
90Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.83197245
91Pathways in cancer_Homo sapiens_hsa052000.82005947
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.81498831
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.81128402
94Small cell lung cancer_Homo sapiens_hsa052220.80640470
95Thyroid hormone synthesis_Homo sapiens_hsa049180.79692220
96Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79551651
97Calcium signaling pathway_Homo sapiens_hsa040200.78853848
98Alcoholism_Homo sapiens_hsa050340.77904108
99Phospholipase D signaling pathway_Homo sapiens_hsa040720.77876248
100Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77797641
101Taste transduction_Homo sapiens_hsa047420.77159088
102MAPK signaling pathway_Homo sapiens_hsa040100.76669114
103Type II diabetes mellitus_Homo sapiens_hsa049300.76132424
104Viral myocarditis_Homo sapiens_hsa054160.76027060
105Phagosome_Homo sapiens_hsa041450.72856027
106Propanoate metabolism_Homo sapiens_hsa006400.71275287
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70476003
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69796563
109Butanoate metabolism_Homo sapiens_hsa006500.69208724
110Pancreatic cancer_Homo sapiens_hsa052120.68734700
111Ovarian steroidogenesis_Homo sapiens_hsa049130.67894614
112Choline metabolism in cancer_Homo sapiens_hsa052310.67638028
113VEGF signaling pathway_Homo sapiens_hsa043700.64501839
114Non-small cell lung cancer_Homo sapiens_hsa052230.64379094
115Primary bile acid biosynthesis_Homo sapiens_hsa001200.64257058
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63411170
117mTOR signaling pathway_Homo sapiens_hsa041500.62705324
118Bladder cancer_Homo sapiens_hsa052190.60369888
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60361261
120Endocytosis_Homo sapiens_hsa041440.60125910
121Fanconi anemia pathway_Homo sapiens_hsa034600.59020876
122Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52687331
123Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52554356
124Renin-angiotensin system_Homo sapiens_hsa046140.49757791
125Regulation of autophagy_Homo sapiens_hsa041400.47040953
126Caffeine metabolism_Homo sapiens_hsa002320.46639275
127Mineral absorption_Homo sapiens_hsa049780.45178181
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45038306
129Tryptophan metabolism_Homo sapiens_hsa003800.44471379
130Linoleic acid metabolism_Homo sapiens_hsa005910.43656056
131Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43508106
132Circadian rhythm_Homo sapiens_hsa047100.41762676
133Steroid hormone biosynthesis_Homo sapiens_hsa001400.40894167
134Fatty acid biosynthesis_Homo sapiens_hsa000610.38686925

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