DUSP27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin-myosin filament sliding (GO:0033275)9.41772180
2muscle filament sliding (GO:0030049)9.41772180
3sarcomere organization (GO:0045214)8.60563894
4negative regulation of potassium ion transmembrane transporter activity (GO:1901017)8.03691732
5actin-mediated cell contraction (GO:0070252)7.72646979
6cardiac myofibril assembly (GO:0055003)7.52709852
7myofibril assembly (GO:0030239)7.25514354
8negative regulation of potassium ion transmembrane transport (GO:1901380)6.92793826
9regulation of skeletal muscle contraction (GO:0014819)6.92086511
10plasma membrane repair (GO:0001778)6.87443247
11cardiac muscle cell development (GO:0055013)6.07426599
12cardiac muscle contraction (GO:0060048)5.84544645
13actin filament-based movement (GO:0030048)5.75395829
14striated muscle contraction (GO:0006941)5.74723371
15cardiac cell development (GO:0055006)5.70006346
16skeletal muscle contraction (GO:0003009)5.67465125
17actomyosin structure organization (GO:0031032)5.61971503
18sarcoplasmic reticulum calcium ion transport (GO:0070296)5.53760070
19positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.48170934
20cardiac muscle tissue morphogenesis (GO:0055008)5.14437306
21regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.13031446
22adult heart development (GO:0007512)4.83849711
23response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.77601204
24muscle tissue morphogenesis (GO:0060415)4.76745740
25ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.74314887
26tricarboxylic acid cycle (GO:0006099)4.71820621
27regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.65491042
28NADH metabolic process (GO:0006734)4.63198093
29cardiac muscle hypertrophy (GO:0003300)4.61410932
30regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO4.60515517
31regulation of sarcomere organization (GO:0060297)4.55650032
32ventricular cardiac muscle cell action potential (GO:0086005)4.43738393
33striated muscle hypertrophy (GO:0014897)4.42116980
34carnitine shuttle (GO:0006853)4.38997582
35regulation of relaxation of muscle (GO:1901077)4.37462250
36regulation of actin filament-based movement (GO:1903115)4.36705947
37positive regulation of calcium ion transmembrane transporter activity (GO:1901021)4.34930467
38myotube cell development (GO:0014904)4.32033318
39response to inactivity (GO:0014854)4.26583187
40bundle of His cell to Purkinje myocyte communication (GO:0086069)4.25088072
41regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.24520037
42regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.22067433
43striated muscle cell development (GO:0055002)4.11869764
44regulation of striated muscle contraction (GO:0006942)4.08403792
45heart contraction (GO:0060047)4.07623366
46heart process (GO:0003015)4.07623366
47muscle contraction (GO:0006936)4.02647303
48heart trabecula formation (GO:0060347)3.96405367
49skeletal muscle tissue development (GO:0007519)3.94925735
50regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.93830063
51regulation of cell communication by electrical coupling (GO:0010649)3.87251735
52regulation of calcium ion transmembrane transporter activity (GO:1901019)3.86535079
53regulation of calcium ion transmembrane transport (GO:1903169)3.86535079
54muscle hypertrophy (GO:0014896)3.82385242
55glycogen catabolic process (GO:0005980)3.77424950
56regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.74761631
57regulation of acyl-CoA biosynthetic process (GO:0050812)3.74708811
58positive regulation of myotube differentiation (GO:0010831)3.73214775
59regulation of the force of heart contraction (GO:0002026)3.69870875
60regulation of membrane repolarization (GO:0060306)3.66910435
61muscle system process (GO:0003012)3.63587087
62regulation of cardiac muscle cell contraction (GO:0086004)3.63434007
63glucan biosynthetic process (GO:0009250)3.62467944
64glycogen biosynthetic process (GO:0005978)3.62467944
65muscle cell development (GO:0055001)3.62153133
66muscle cell fate commitment (GO:0042693)3.61356784
67muscle cell cellular homeostasis (GO:0046716)3.60159657
68membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.59339103
69fatty acid transmembrane transport (GO:1902001)3.59136482
70regulation of muscle contraction (GO:0006937)3.57441284
71regulation of muscle system process (GO:0090257)3.57036350
72regulation of cofactor metabolic process (GO:0051193)3.56363038
73regulation of coenzyme metabolic process (GO:0051196)3.56363038
74muscle fiber development (GO:0048747)3.55302893
75muscle atrophy (GO:0014889)3.53534830
76glucan catabolic process (GO:0009251)3.53472727
77negative regulation of potassium ion transport (GO:0043267)3.53372163
78striated muscle adaptation (GO:0014888)3.52902064
79oxidative phosphorylation (GO:0006119)3.52017068
80skeletal muscle adaptation (GO:0043501)3.51337673
81muscle organ development (GO:0007517)3.48550392
82muscle structure development (GO:0061061)3.47471662
83striated muscle atrophy (GO:0014891)3.46340181
84cytidine metabolic process (GO:0046087)3.44734285
85cytidine catabolic process (GO:0006216)3.44734285
86cytidine deamination (GO:0009972)3.44734285
87positive regulation of cation channel activity (GO:2001259)3.42606938
88negative regulation of calcium ion transmembrane transport (GO:1903170)3.41898554
89negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.41898554
902-oxoglutarate metabolic process (GO:0006103)3.39409572
91regulation of myoblast differentiation (GO:0045661)3.39401662
92regulation of cardiac muscle contraction (GO:0055117)3.39336547
93regulation of posttranscriptional gene silencing (GO:0060147)3.38742563
94regulation of gene silencing by miRNA (GO:0060964)3.38742563
95regulation of gene silencing by RNA (GO:0060966)3.38742563
96negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.38425613
97relaxation of cardiac muscle (GO:0055119)3.38188280
98regulation of ATP catabolic process (GO:1903289)3.35313324
99regulation of ATPase activity (GO:0043462)3.35313324
100response to caffeine (GO:0031000)3.35180257
101regulation of heart contraction (GO:0008016)3.34437927
102cellular polysaccharide catabolic process (GO:0044247)3.32027504
103response to muscle activity (GO:0014850)3.29177964
104cardiac muscle cell action potential (GO:0086001)3.28699461
105cardiac muscle cell action potential involved in contraction (GO:0086002)3.27449976
106cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.23526964
107negative regulation of protein localization to cell surface (GO:2000009)3.20647350
108skeletal muscle fiber development (GO:0048741)3.19903205
109ventricular cardiac muscle cell development (GO:0055015)3.19545863
110cardiac muscle hypertrophy in response to stress (GO:0014898)3.19162658
111muscle hypertrophy in response to stress (GO:0003299)3.19162658
112cardiac muscle adaptation (GO:0014887)3.19162658
113cell communication involved in cardiac conduction (GO:0086065)3.17190784
114negative regulation of striated muscle cell apoptotic process (GO:0010664)3.14550702
115mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.13738419
116negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.10590386
117regulation of cardioblast differentiation (GO:0051890)3.09601723
118regulation of heart rate (GO:0002027)3.08162736
119pyrimidine ribonucleoside catabolic process (GO:0046133)3.04490598
120skeletal muscle tissue regeneration (GO:0043403)3.02028030
121carnitine transmembrane transport (GO:1902603)3.00715645
122regulation of striated muscle cell apoptotic process (GO:0010662)2.94476115
123epithelial cell-cell adhesion (GO:0090136)2.91179620
124negative regulation of cell size (GO:0045792)2.88602350
125muscle adaptation (GO:0043500)2.87873211
126IMP metabolic process (GO:0046040)2.87242976
127creatine metabolic process (GO:0006600)2.86864859
128energy coupled proton transport, down electrochemical gradient (GO:0015985)2.86646049
129ATP synthesis coupled proton transport (GO:0015986)2.86646049

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.07044573
2KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.60111114
3KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.60111114
4KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.60111114
5E2F7_22180533_ChIP-Seq_HELA_Human3.49749684
6* SMAD3_22036565_ChIP-Seq_ESCs_Mouse3.26475090
7* SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.23206090
8PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.07747807
9CDX2_19796622_ChIP-Seq_MESCs_Mouse3.05459423
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.03752280
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.00302576
12BP1_19119308_ChIP-ChIP_Hs578T_Human2.99940808
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.93911889
14NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.92611748
15POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.80726109
16STAT3_1855785_ChIP-Seq_MESCs_Mouse2.76955515
17* ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.67795747
18* NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.58812215
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.51830907
20ZNF263_19887448_ChIP-Seq_K562_Human2.47616766
21* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.45615902
22TBX20_22328084_ChIP-Seq_HEART_Mouse2.34806722
23TBX20_22080862_ChIP-Seq_HEART_Mouse2.34806722
24MYC_18555785_ChIP-Seq_MESCs_Mouse2.30327963
25TCF3_18692474_ChIP-Seq_MEFs_Mouse2.26316087
26SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.22253710
27EP300_21415370_ChIP-Seq_HL-1_Mouse2.13308626
28* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.09082831
29NANOG_18555785_ChIP-Seq_MESCs_Mouse2.07540163
30EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.07380655
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.06739943
32TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05296513
33MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.02843325
34* ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.99417780
35* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.98940309
36* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.94071359
37MYC_19079543_ChIP-ChIP_MESCs_Mouse1.91356849
38TRIM28_21343339_ChIP-Seq_HEK293_Human1.90468526
39SOX2_18555785_ChIP-Seq_MESCs_Mouse1.75667880
40* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.74528508
41HIF1A_21447827_ChIP-Seq_MCF-7_Human1.72952303
42SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.72402673
43THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.67839195
44GATA4_21415370_ChIP-Seq_HL-1_Mouse1.65413740
45ESR1_20079471_ChIP-ChIP_T-47D_Human1.65055257
46CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.64858255
47POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.62544686
48NFIB_24661679_ChIP-Seq_LUNG_Mouse1.61316498
49* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.60674424
50* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.57728744
51POU5F1_16518401_ChIP-PET_MESCs_Mouse1.57125773
52NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.54766960
53BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.52821984
54NANOG_21062744_ChIP-ChIP_HESCs_Human1.51649636
55RARG_19884340_ChIP-ChIP_MEFs_Mouse1.51647825
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51174408
57FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.49477750
58SOX2_18692474_ChIP-Seq_MEFs_Mouse1.47582443
59NANOG_18692474_ChIP-Seq_MEFs_Mouse1.46920133
60ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.46720303
61KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.46529924
62GATA1_22025678_ChIP-Seq_K562_Human1.46110355
63NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.46097889
64KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.45288597
65ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.44027240
66ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40437115
67NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.36835922
68OCT4_18692474_ChIP-Seq_MEFs_Mouse1.36775717
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.35768569
70RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.33590660
71NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.32554959
72* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.31593896
73E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31462114
74PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.31208122
75* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.29425578
76BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.28698611
77ATF3_27146783_Chip-Seq_COLON_Human1.26797431
78HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24823512
79DROSHA_22980978_ChIP-Seq_HELA_Human1.24666527
80CTCF_27219007_Chip-Seq_Bcells_Human1.23610421
81NELFA_20434984_ChIP-Seq_ESCs_Mouse1.23511492
82EZH2_27294783_Chip-Seq_ESCs_Mouse1.20763129
83MYC_18358816_ChIP-ChIP_MESCs_Mouse1.20255205
84EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.15429545
85* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.15085562
86CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.14857908
87CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.14829294
88ELK3_25401928_ChIP-Seq_HUVEC_Human1.14326020
89KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12958067
90FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.12529481
91PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.11022807
92ZFP281_27345836_Chip-Seq_ESCs_Mouse1.09795611
93MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09689672
94KDM2B_26808549_Chip-Seq_DND41_Human1.07554924
95LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07180133
96GBX2_23144817_ChIP-Seq_PC3_Human1.06007651
97* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.05503312
98RACK7_27058665_Chip-Seq_MCF-7_Human1.05342932
99ESR2_21235772_ChIP-Seq_MCF-7_Human1.04389045
100SMC3_22415368_ChIP-Seq_MEFs_Mouse1.03408831
101MYC_22102868_ChIP-Seq_BL_Human1.02479104
102POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.02353029
103ISL1_27105846_Chip-Seq_CPCs_Mouse1.01136857
104ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01051997
105TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98847211
106EZH2_27304074_Chip-Seq_ESCs_Mouse0.98266011
107SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97529308
108KDM2B_26808549_Chip-Seq_SUP-B15_Human0.97437386
109KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.97431768
110TP53_22127205_ChIP-Seq_IMR90_Human0.97117361
111* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.97102851
112YY1_22570637_ChIP-Seq_MALME-3M_Human0.96975117
113MTF2_20144788_ChIP-Seq_MESCs_Mouse0.96835314
114YY1_21170310_ChIP-Seq_MESCs_Mouse0.95863910
115TP63_17297297_ChIP-ChIP_HaCaT_Human0.95636294
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.95535342
117SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.95396998
118NR3C1_23031785_ChIP-Seq_PC12_Mouse0.95111187
119TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94751970
120EZH2_18974828_ChIP-Seq_MESCs_Mouse0.94704741
121RNF2_18974828_ChIP-Seq_MESCs_Mouse0.94704741
122VDR_22108803_ChIP-Seq_LS180_Human0.93394202
123RARB_27405468_Chip-Seq_BRAIN_Mouse0.92904191
124GATA1_19941827_ChIP-Seq_MEL_Mouse0.92272058
125SOX2_21211035_ChIP-Seq_LN229_Gbm0.92264974
126GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92200717
127CLOCK_20551151_ChIP-Seq_293T_Human0.92199261
128YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.90631870
129THAP11_20581084_ChIP-Seq_MESCs_Mouse0.89693355
130SALL1_21062744_ChIP-ChIP_HESCs_Human0.89651406
131LXR_22158963_ChIP-Seq_LIVER_Mouse0.88732834
132ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.88666198
133MYCN_18555785_ChIP-Seq_MESCs_Mouse0.87609715
134MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87506299
135PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.87474572
136RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.87336703
137* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.86719493
138* SMAD3_21741376_ChIP-Seq_HESCs_Human0.86524555
139CTCF_21964334_Chip-Seq_Bcells_Human0.86302417
140NRF2_20460467_ChIP-Seq_MEFs_Mouse0.86126947
141NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.86126947
142MYC_27129775_Chip-Seq_CORNEA_Mouse0.86033274
143NANOG_16153702_ChIP-ChIP_HESCs_Human0.85831318
144STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.85055804
145CIITA_25753668_ChIP-Seq_RAJI_Human0.84958188
146SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.84869720
147GF1_26923725_Chip-Seq_HPCs_Mouse0.84062661
148PCGF2_27294783_Chip-Seq_NPCs_Mouse0.83566470
149PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.82585895
150WT1_25993318_ChIP-Seq_PODOCYTE_Human0.82451904
151GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.81551508
152IGF1R_20145208_ChIP-Seq_DFB_Human0.81226925
153* SUZ12_27294783_Chip-Seq_NPCs_Mouse0.81219311
154WT1_19549856_ChIP-ChIP_CCG9911_Human0.81113286
155SMAD4_21741376_ChIP-Seq_HESCs_Human0.81105913
156SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.80331206
157HTT_18923047_ChIP-ChIP_STHdh_Human0.79577358
158OCT4_20526341_ChIP-Seq_ESCs_Human0.79260464
159CTNNB1_20460455_ChIP-Seq_HCT116_Human0.79179181
160PPARA_22158963_ChIP-Seq_LIVER_Mouse0.78211322
161* EZH2_27294783_Chip-Seq_NPCs_Mouse0.76899453
162* CRX_20693478_ChIP-Seq_RETINA_Mouse0.76656680
163PCGF2_27294783_Chip-Seq_ESCs_Mouse0.76296825
164SOX9_24532713_ChIP-Seq_HFSC_Mouse0.76280450
165RXR_22158963_ChIP-Seq_LIVER_Mouse0.76115251
166* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.75994193
167TP53_23651856_ChIP-Seq_MEFs_Mouse0.75695277
168AR_21572438_ChIP-Seq_LNCaP_Human0.74868055
169CJUN_26792858_Chip-Seq_BT549_Human0.74174817
170JARID2_20075857_ChIP-Seq_MESCs_Mouse0.73968868
171* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.72657263
172SMAD4_21799915_ChIP-Seq_A2780_Human0.72212660
173* GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.71600113
174TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.70164204

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.21966667
2MP0000751_myopathy4.98719762
3MP0004084_abnormal_cardiac_muscle4.93827827
4MP0000749_muscle_degeneration4.76307755
5MP0003646_muscle_fatigue4.56673451
6MP0004036_abnormal_muscle_relaxation3.82738884
7MP0004145_abnormal_muscle_electrophysio3.66608006
8MP0004215_abnormal_myocardial_fiber3.63886380
9MP0005330_cardiomyopathy3.43458379
10MP0000750_abnormal_muscle_regeneration3.32691573
11MP0004087_abnormal_muscle_fiber3.30537047
12MP0002106_abnormal_muscle_physiology3.02003024
13MP0002269_muscular_atrophy2.92357650
14MP0000747_muscle_weakness2.67468220
15MP0005620_abnormal_muscle_contractility2.58073854
16MP0002972_abnormal_cardiac_muscle2.56348871
17MP0000759_abnormal_skeletal_muscle2.53242790
18MP0010630_abnormal_cardiac_muscle2.47665695
19MP0005369_muscle_phenotype2.46298204
20MP0003137_abnormal_impulse_conducting2.44205029
21MP0005451_abnormal_body_composition2.39327737
22MP0008775_abnormal_heart_ventricle2.33796290
23MP0004233_abnormal_muscle_weight2.18691112
24MP0003950_abnormal_plasma_membrane2.11672281
25MP0005385_cardiovascular_system_phenoty2.03642962
26MP0001544_abnormal_cardiovascular_syste2.03642962
27MP0003828_pulmonary_edema1.89898314
28MP0006138_congestive_heart_failure1.85744541
29MP0002332_abnormal_exercise_endurance1.84249634
30MP0003221_abnormal_cardiomyocyte_apopto1.81772425
31MP0000733_abnormal_muscle_development1.79750944
32MP0002127_abnormal_cardiovascular_syste1.77784386
33MP0004130_abnormal_muscle_cell1.73691930
34MP0004484_altered_response_of1.72651770
35MP0003567_abnormal_fetal_cardiomyocyte1.56229919
36MP0003705_abnormal_hypodermis_morpholog1.54443059
37MP0004085_abnormal_heartbeat1.49719979
38MP0006036_abnormal_mitochondrial_physio1.41429903
39MP0000013_abnormal_adipose_tissue1.38286736
40MP0003806_abnormal_nucleotide_metabolis1.29499814
41MP0002108_abnormal_muscle_morphology1.28945723
42MP0005623_abnormal_meninges_morphology1.22964746
43MP0000266_abnormal_heart_morphology1.20822425
44MP0005666_abnormal_adipose_tissue1.20030057
45MP0003566_abnormal_cell_adhesion1.19649776
46MP0005266_abnormal_metabolism1.18190169
47MP0004270_analgesia1.11483286
48MP0001661_extended_life_span1.11138107
49MP0004510_myositis1.10755705
50MP0004185_abnormal_adipocyte_glucose1.10411808
51MP0006035_abnormal_mitochondrial_morpho1.04291757
52MP0003941_abnormal_skin_development1.01436064
53MP0003984_embryonic_growth_retardation1.00416145
54MP0002088_abnormal_embryonic_growth/wei0.99562719
55MP0005380_embryogenesis_phenotype0.93608291
56MP0001672_abnormal_embryogenesis/_devel0.93608291
57MP0003279_aneurysm0.91165768
58MP0005670_abnormal_white_adipose0.89371031
59MP0004197_abnormal_fetal_growth/weight/0.84577943
60MP0004133_heterotaxia0.84196851
61MP0010352_gastrointestinal_tract_polyps0.84009546
62MP0001730_embryonic_growth_arrest0.82222152
63MP0005375_adipose_tissue_phenotype0.81305257
64MP0010030_abnormal_orbit_morphology0.80441178
65MP0002925_abnormal_cardiovascular_devel0.76508203
66MP0004272_abnormal_basement_membrane0.76042593
67MP0004957_abnormal_blastocyst_morpholog0.75962400
68MP0002234_abnormal_pharynx_morphology0.74817333
69MP0002128_abnormal_blood_circulation0.71013540
70MP0000343_altered_response_to0.70859047
71MP0002086_abnormal_extraembryonic_tissu0.69183247
72MP0001697_abnormal_embryo_size0.68207094
73MP0002084_abnormal_developmental_patter0.68000691
74MP0002085_abnormal_embryonic_tissue0.67991128
75MP0003045_fibrosis0.67950590
76MP0008438_abnormal_cutaneous_collagen0.66689379
77MP0008057_abnormal_DNA_replication0.63384322
78MP0005165_increased_susceptibility_to0.63036678
79MP0000762_abnormal_tongue_morphology0.61520434
80MP0003283_abnormal_digestive_organ0.61206302
81MP0003123_paternal_imprinting0.60919132
82MP0000767_abnormal_smooth_muscle0.59598517
83MP0003077_abnormal_cell_cycle0.58879094
84MP0003111_abnormal_nucleus_morphology0.57943700
85MP0009780_abnormal_chondrocyte_physiolo0.57713796
86MP0005275_abnormal_skin_tensile0.57005686
87MP0002080_prenatal_lethality0.56256072
88MP0002971_abnormal_brown_adipose0.54019864
89MP0000350_abnormal_cell_proliferation0.53442136
90MP0001784_abnormal_fluid_regulation0.52658822
91MP0010368_abnormal_lymphatic_system0.50946116
92MP0002877_abnormal_melanocyte_morpholog0.49998815
93MP0001849_ear_inflammation0.49177428
94MP0010094_abnormal_chromosome_stability0.48960490
95MP0001299_abnormal_eye_distance/0.48748238
96MP0002249_abnormal_larynx_morphology0.48461484
97MP0001614_abnormal_blood_vessel0.47285198
98MP0003119_abnormal_digestive_system0.47169855
99MP0005076_abnormal_cell_differentiation0.45867069
100MP0002822_catalepsy0.45618807
101MP0000003_abnormal_adipose_tissue0.44713438
102MP0008569_lethality_at_weaning0.42549768
103MP0003935_abnormal_craniofacial_develop0.41921695
104MP0002114_abnormal_axial_skeleton0.40944807
105MP0000372_irregular_coat_pigmentation0.39853436
106MP0002653_abnormal_ependyma_morphology0.39548751
107MP0000428_abnormal_craniofacial_morphol0.38449969
108MP0005023_abnormal_wound_healing0.38107236
109MP0008770_decreased_survivor_rate0.37783220
110MP0008961_abnormal_basal_metabolism0.37583054
111MP0000230_abnormal_systemic_arterial0.36631443
112MP0002078_abnormal_glucose_homeostasis0.33956341
113MP0009384_cardiac_valve_regurgitation0.33319687
114MP0004134_abnormal_chest_morphology0.32934788
115MP0005167_abnormal_blood-brain_barrier0.32671189
116MP0003879_abnormal_hair_cell0.31458140
117MP0002638_abnormal_pupillary_reflex0.31268378
118MP0003948_abnormal_gas_homeostasis0.30884936
119MP0005584_abnormal_enzyme/coenzyme_acti0.29174112
120MP0004147_increased_porphyrin_level0.28355391
121MP0005187_abnormal_penis_morphology0.26828551
122MP0003656_abnormal_erythrocyte_physiolo0.26636325
123MP0005376_homeostasis/metabolism_phenot0.25765616
124MP0005535_abnormal_body_temperature0.23680674
125MP0002896_abnormal_bone_mineralization0.22786382
126MP0001879_abnormal_lymphatic_vessel0.22726834
127MP0005334_abnormal_fat_pad0.22397212
128MP0009250_abnormal_appendicular_skeleto0.20818002
129MP0009672_abnormal_birth_weight0.20785740
130MP0005166_decreased_susceptibility_to0.20624174
131MP0005503_abnormal_tendon_morphology0.20406860
132MP0005452_abnormal_adipose_tissue0.18243518
133MP0009115_abnormal_fat_cell0.17547123
134MP0005595_abnormal_vascular_smooth0.17173813
135MP0008004_abnormal_stomach_pH0.17065244

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.47656666
2Exercise-induced muscle cramps (HP:0003710)6.22815920
3Exercise-induced myalgia (HP:0003738)6.05344587
4Calf muscle hypertrophy (HP:0008981)5.98541710
5Muscle fiber inclusion bodies (HP:0100299)5.98122515
6Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.97357434
7Muscle fiber splitting (HP:0003555)5.81633983
8Muscle hypertrophy of the lower extremities (HP:0008968)5.73416702
9Type 1 muscle fiber predominance (HP:0003803)5.55789109
10Hyporeflexia of lower limbs (HP:0002600)5.30248853
11Nemaline bodies (HP:0003798)5.27096246
12Ventricular tachycardia (HP:0004756)5.20939837
13Abnormality of the calf musculature (HP:0001430)5.18049246
14Subaortic stenosis (HP:0001682)4.74739411
15Abnormality of the left ventricular outflow tract (HP:0011103)4.74739411
16EMG: myopathic abnormalities (HP:0003458)4.70675995
17Difficulty running (HP:0009046)4.59809381
18Increased connective tissue (HP:0009025)4.56666481
19Distal arthrogryposis (HP:0005684)4.33359143
20Myoglobinuria (HP:0002913)4.12246190
21Atrial fibrillation (HP:0005110)4.11188849
22Round ear (HP:0100830)3.99983163
23Lipoatrophy (HP:0100578)3.98464304
24Right ventricular cardiomyopathy (HP:0011663)3.85985713
25Primary atrial arrhythmia (HP:0001692)3.84188730
26Difficulty climbing stairs (HP:0003551)3.82815805
27Supraventricular tachycardia (HP:0004755)3.73269752
28Supraventricular arrhythmia (HP:0005115)3.67540086
29Myopathic facies (HP:0002058)3.46326226
30Ulnar deviation of the wrist (HP:0003049)3.43763419
31Rhabdomyolysis (HP:0003201)3.40440485
32Asymmetric septal hypertrophy (HP:0001670)3.35783780
33Dilated cardiomyopathy (HP:0001644)3.34073883
34Myotonia (HP:0002486)3.33236229
35Mildly elevated creatine phosphokinase (HP:0008180)3.22758537
36Neck muscle weakness (HP:0000467)3.22437899
37Distal lower limb muscle weakness (HP:0009053)3.15617729
38EMG: neuropathic changes (HP:0003445)3.12137223
39Abnormality of skeletal muscle fiber size (HP:0012084)3.06003487
40Ventricular arrhythmia (HP:0004308)3.01176108
41Syncope (HP:0001279)2.91298483
42Areflexia of lower limbs (HP:0002522)2.88890602
43Increased variability in muscle fiber diameter (HP:0003557)2.86882037
44Malignant hyperthermia (HP:0002047)2.83630818
45Prolonged QT interval (HP:0001657)2.78344356
46Palpitations (HP:0001962)2.77591822
47Generalized muscle weakness (HP:0003324)2.77068765
48Bundle branch block (HP:0011710)2.73102654
49Calcaneovalgus deformity (HP:0001848)2.68034271
50Hip contracture (HP:0003273)2.65090250
51Gowers sign (HP:0003391)2.62494958
52Muscle stiffness (HP:0003552)2.61414378
53Centrally nucleated skeletal muscle fibers (HP:0003687)2.57052777
54Hypoplastic ischia (HP:0003175)2.55627646
55Abnormality of the neuromuscular junction (HP:0003398)2.49613090
56Fatigable weakness (HP:0003473)2.49613090
57Distal lower limb amyotrophy (HP:0008944)2.45597119
58Heart block (HP:0012722)2.42883558
59Testicular atrophy (HP:0000029)2.40608801
60Deformed tarsal bones (HP:0008119)2.40114250
61Atrioventricular block (HP:0001678)2.37347982
62Abnormal atrioventricular conduction (HP:0005150)2.36379517
63Scapular winging (HP:0003691)2.32395531
64Progressive muscle weakness (HP:0003323)2.31512357
65Fetal akinesia sequence (HP:0001989)2.31306137
66Rimmed vacuoles (HP:0003805)2.29272640
67Weak cry (HP:0001612)2.28318217
68Bulbar palsy (HP:0001283)2.25564515
69Popliteal pterygium (HP:0009756)2.22556732
70Abnormality of the ischium (HP:0003174)2.20669821
71Absent phalangeal crease (HP:0006109)2.20094538
72Frequent falls (HP:0002359)2.14405991
73Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.14375859
74Limb-girdle muscle atrophy (HP:0003797)2.12489708
75Ragged-red muscle fibers (HP:0003200)2.11279608
76Ventricular fibrillation (HP:0001663)2.07386460
77Muscular dystrophy (HP:0003560)2.06355687
78Aplasia of the musculature (HP:0100854)2.04959208
79Slender build (HP:0001533)2.03485303
80Lower limb amyotrophy (HP:0007210)2.01538987
81Hyperkalemia (HP:0002153)2.00740647
82Ependymoma (HP:0002888)2.00699790
83Abnormal EKG (HP:0003115)1.99532587
84Spinal rigidity (HP:0003306)1.97864534
85Waddling gait (HP:0002515)1.95943895
86Abnormality of the foot musculature (HP:0001436)1.95918227
87Type 2 muscle fiber atrophy (HP:0003554)1.95323318
88Left ventricular hypertrophy (HP:0001712)1.93601200
89Abnormality of the shoulder girdle musculature (HP:0001435)1.91515071
90Palmoplantar keratoderma (HP:0000982)1.89977756
91Facial diplegia (HP:0001349)1.88837952
92Proximal amyotrophy (HP:0007126)1.86840440
93Muscle fiber atrophy (HP:0100295)1.84478148
94Trismus (HP:0000211)1.82516638
95Multiple enchondromatosis (HP:0005701)1.79594636
96Limb-girdle muscle weakness (HP:0003325)1.79580509
97Abnormality of the calcaneus (HP:0008364)1.79284052
98Limited hip movement (HP:0008800)1.77840440
99Foot dorsiflexor weakness (HP:0009027)1.76608120
100Easy fatigability (HP:0003388)1.76160589
101Steppage gait (HP:0003376)1.74894663
102Abnormal finger flexion creases (HP:0006143)1.73376424
103Hypoplastic heart (HP:0001961)1.71558057
104Thin ribs (HP:0000883)1.70855604
105Respiratory insufficiency due to muscle weakness (HP:0002747)1.70848274
106Exercise intolerance (HP:0003546)1.59412559
107Metatarsus adductus (HP:0001840)1.59237787
108Long clavicles (HP:0000890)1.57811228
109Nonprogressive disorder (HP:0003680)1.47035939
110Abnormality of the musculature of the pelvis (HP:0001469)1.46983417

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.70958978
2TTN5.09330465
3PHKG23.47787542
4PHKG13.47787542
5NEK13.20299354
6PKN22.76791011
7PDK32.72957872
8PDK42.72957872
9CDK122.69323355
10MUSK2.65971952
11DMPK2.42064064
12TRIB32.29883846
13MYLK2.14714140
14PDK21.74408064
15PIK3CG1.70201629
16LMTK21.67970903
17ZAK1.66431899
18MAPKAPK31.63124436
19BCKDK1.58714980
20STK241.54952345
21PIK3CA1.47789058
22PINK11.32835016
23MAP2K31.30124970
24MARK11.28509963
25ICK1.23872052
26TTK1.18856260
27STK38L1.17954793
28MAP3K101.16938281
29MOS1.11167649
30MAP3K71.11157634
31EPHA21.09879840
32ILK1.06216495
33FLT31.05607444
34MAPK121.04410149
35RPS6KB21.03159863
36NEK91.01093303
37AKT21.00569427
38TIE10.93630481
39LATS20.92412575
40PDGFRA0.91173410
41CDC42BPA0.91043676
42CAMK2G0.88575775
43RIPK10.87190160
44NME10.86961647
45CCNB10.84295459
46STK40.84215119
47MAP3K50.81801612
48MTOR0.79493603
49PRKAA10.78008168
50MAP2K40.75508760
51PRKD10.75051412
52TRPM70.74686689
53ROCK10.73074609
54GRK70.72409866
55PAK30.71297411
56TGFBR20.69691480
57PAK40.69541372
58LATS10.69204418
59MAP3K30.67543711
60CAMK2A0.63958439
61CAMK10.63100688
62MAPK40.62604414
63CAMK40.57921173
64PRKAA20.57340229
65ALK0.56893055
66PRKG10.56615967
67PKN10.56257775
68DAPK30.55423190
69WEE10.53912617
70CAMK2D0.53423388
71MAP2K10.53168257
72ERBB30.50845560
73MAPK70.50175402
74WNK10.50039495
75DYRK1B0.49881161
76CAMK2B0.49668567
77EPHA30.49049212
78CDK40.49034807
79PLK10.47779024
80CDK70.47165396
81PRKACB0.45185216
82STK380.45005750
83MAP3K60.44654203
84KSR20.44407285
85TYRO30.43268534
86SGK30.41682895
87AURKB0.41402773
88ROCK20.41154195
89DDR20.40646339
90STK100.37588826
91AKT30.37290829
92SGK20.33942876
93MAP3K130.33868222
94EEF2K0.33814539
95RPS6KC10.33069060
96RPS6KL10.33069060
97PRKG20.32690740
98EPHB10.31543278
99PAK20.30605108
100MET0.30406338
101NEK20.30202484
102MAP2K60.29644099
103CSNK1D0.29624306
104GRK50.29149826
105CHEK10.29083382
106MARK20.28853489
107PRKACG0.27533086
108LIMK10.27215133
109MAP3K80.25706431
110MAPK100.23675674
111CDK20.23555741
112MAPK110.23331763
113RPS6KA10.22801518
114CDC70.21833116
115PTK60.21393689
116PRKACA0.21159323
117TAOK20.20921934
118RPS6KA30.20546741
119CHEK20.20498898
120RPS6KA60.20482609
121PDPK10.20317716
122BRD40.20029344
123BLK0.19575034
124SIK10.19464699
125CSNK1E0.19336108
126SGK10.18444203
127BMX0.17960982
128TBK10.17293229
129PRPF4B0.16240953
130STK110.15697250
131ZAP700.15098515
132SGK4940.14554155
133SGK2230.14554155
134RPS6KB10.14293182
135MAP3K10.13592717
136PRKCE0.12605501
137PDK10.12602787
138FGFR30.12563929
139NLK0.12329014
140PTK2B0.12003859

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.17984110
2Cardiac muscle contraction_Homo sapiens_hsa042604.41886445
3Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.34871873
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.33764111
5Dilated cardiomyopathy_Homo sapiens_hsa054144.16043341
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.23313255
7Carbon metabolism_Homo sapiens_hsa012002.47782110
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.45256107
9Parkinsons disease_Homo sapiens_hsa050122.32567847
10Propanoate metabolism_Homo sapiens_hsa006402.05044459
11Oxidative phosphorylation_Homo sapiens_hsa001901.98981947
12Viral myocarditis_Homo sapiens_hsa054161.90499015
13Biosynthesis of amino acids_Homo sapiens_hsa012301.80820126
14Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.79533276
15Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.73044114
16Fatty acid degradation_Homo sapiens_hsa000711.67206036
17Huntingtons disease_Homo sapiens_hsa050161.59491942
18Alzheimers disease_Homo sapiens_hsa050101.56720618
19Tight junction_Homo sapiens_hsa045301.48365043
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.45130795
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.38154527
22Fructose and mannose metabolism_Homo sapiens_hsa000511.33612546
23Pyruvate metabolism_Homo sapiens_hsa006201.33027258
24Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.32520800
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.27223966
26Glucagon signaling pathway_Homo sapiens_hsa049221.21564843
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.18203834
28Galactose metabolism_Homo sapiens_hsa000521.17948238
29Renin secretion_Homo sapiens_hsa049241.17944234
30Fatty acid metabolism_Homo sapiens_hsa012121.17230122
31Focal adhesion_Homo sapiens_hsa045101.13779975
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.11981375
33Mismatch repair_Homo sapiens_hsa034301.07841759
34Insulin signaling pathway_Homo sapiens_hsa049101.06440259
35RNA transport_Homo sapiens_hsa030131.04315385
36Adherens junction_Homo sapiens_hsa045201.04114364
37Insulin resistance_Homo sapiens_hsa049311.03893227
38Starch and sucrose metabolism_Homo sapiens_hsa005001.03710439
39Central carbon metabolism in cancer_Homo sapiens_hsa052301.02764900
40Phenylalanine metabolism_Homo sapiens_hsa003601.01903812
41Gastric acid secretion_Homo sapiens_hsa049711.01441069
42HIF-1 signaling pathway_Homo sapiens_hsa040660.98420569
43AMPK signaling pathway_Homo sapiens_hsa041520.91514845
44cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84112972
45Lysine degradation_Homo sapiens_hsa003100.83917434
46mTOR signaling pathway_Homo sapiens_hsa041500.80744333
47One carbon pool by folate_Homo sapiens_hsa006700.80717774
48Insulin secretion_Homo sapiens_hsa049110.78088246
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.77226425
50GnRH signaling pathway_Homo sapiens_hsa049120.75784463
51Adipocytokine signaling pathway_Homo sapiens_hsa049200.75584108
52DNA replication_Homo sapiens_hsa030300.71619914
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.71253684
54Oxytocin signaling pathway_Homo sapiens_hsa049210.70934932
55ECM-receptor interaction_Homo sapiens_hsa045120.70806124
56Arginine and proline metabolism_Homo sapiens_hsa003300.70548799
57Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.69096270
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.68839120
59Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.67205110
60Circadian entrainment_Homo sapiens_hsa047130.66786033
61Notch signaling pathway_Homo sapiens_hsa043300.65739539
62Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65532767
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65350497
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65243626
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.65084625
66Hippo signaling pathway_Homo sapiens_hsa043900.63887162
67cAMP signaling pathway_Homo sapiens_hsa040240.63483814
68Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61856211
69Proteoglycans in cancer_Homo sapiens_hsa052050.61202395
70mRNA surveillance pathway_Homo sapiens_hsa030150.61093461
71RNA degradation_Homo sapiens_hsa030180.61074044
72Basal cell carcinoma_Homo sapiens_hsa052170.60408962
73Long-term potentiation_Homo sapiens_hsa047200.58740918
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57636741
75Aldosterone synthesis and secretion_Homo sapiens_hsa049250.56666674
76Calcium signaling pathway_Homo sapiens_hsa040200.54756583
77Ovarian steroidogenesis_Homo sapiens_hsa049130.53263104
78Salivary secretion_Homo sapiens_hsa049700.52089671
79Spliceosome_Homo sapiens_hsa030400.50361599
80Vascular smooth muscle contraction_Homo sapiens_hsa042700.50327184
81Pancreatic secretion_Homo sapiens_hsa049720.50049417
82Cell cycle_Homo sapiens_hsa041100.47053336
83Arginine biosynthesis_Homo sapiens_hsa002200.44511097
84Nitrogen metabolism_Homo sapiens_hsa009100.44138672
85Fatty acid biosynthesis_Homo sapiens_hsa000610.43697214
86MicroRNAs in cancer_Homo sapiens_hsa052060.42784026
87Base excision repair_Homo sapiens_hsa034100.42576140
88Leukocyte transendothelial migration_Homo sapiens_hsa046700.41579281
89p53 signaling pathway_Homo sapiens_hsa041150.41153575
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38653751
91Cholinergic synapse_Homo sapiens_hsa047250.38024132
92Platelet activation_Homo sapiens_hsa046110.37353199
93Nucleotide excision repair_Homo sapiens_hsa034200.36441871
94Amoebiasis_Homo sapiens_hsa051460.36347591
95Hedgehog signaling pathway_Homo sapiens_hsa043400.35319078
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.35273538
97Cysteine and methionine metabolism_Homo sapiens_hsa002700.35093212
98Fatty acid elongation_Homo sapiens_hsa000620.34906121
99PPAR signaling pathway_Homo sapiens_hsa033200.34225848
100Homologous recombination_Homo sapiens_hsa034400.33796696
101Small cell lung cancer_Homo sapiens_hsa052220.33669682
102Circadian rhythm_Homo sapiens_hsa047100.33268295
103Bile secretion_Homo sapiens_hsa049760.32311096
104Amphetamine addiction_Homo sapiens_hsa050310.31026556
105TGF-beta signaling pathway_Homo sapiens_hsa043500.30674562
106RNA polymerase_Homo sapiens_hsa030200.30393491
107Melanogenesis_Homo sapiens_hsa049160.28924049
108beta-Alanine metabolism_Homo sapiens_hsa004100.27924042
109Regulation of autophagy_Homo sapiens_hsa041400.27621446
110Gap junction_Homo sapiens_hsa045400.26619441
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26497137
112Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.26344015
113Pathways in cancer_Homo sapiens_hsa052000.26204958
114Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.24950435
115HTLV-I infection_Homo sapiens_hsa051660.24771350
116Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.24005069
117VEGF signaling pathway_Homo sapiens_hsa043700.23525147
118Pentose phosphate pathway_Homo sapiens_hsa000300.23192481
119FoxO signaling pathway_Homo sapiens_hsa040680.22301134
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.22075400
121Ribosome_Homo sapiens_hsa030100.21329426
122Butanoate metabolism_Homo sapiens_hsa006500.20782062
123Tyrosine metabolism_Homo sapiens_hsa003500.19962443
124Tryptophan metabolism_Homo sapiens_hsa003800.19910267
125Oocyte meiosis_Homo sapiens_hsa041140.19670059
126Viral carcinogenesis_Homo sapiens_hsa052030.19561300
127Fanconi anemia pathway_Homo sapiens_hsa034600.19453624
128Renal cell carcinoma_Homo sapiens_hsa052110.17930547
129Olfactory transduction_Homo sapiens_hsa047400.16170703
130MAPK signaling pathway_Homo sapiens_hsa040100.15731540
131Protein digestion and absorption_Homo sapiens_hsa049740.15314929
132Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.15191348
133Bladder cancer_Homo sapiens_hsa052190.14715378
134Peroxisome_Homo sapiens_hsa041460.13300203
135Long-term depression_Homo sapiens_hsa047300.12446698
136Glioma_Homo sapiens_hsa052140.12330588
137Carbohydrate digestion and absorption_Homo sapiens_hsa049730.10896865
138Endometrial cancer_Homo sapiens_hsa052130.10223181
139Estrogen signaling pathway_Homo sapiens_hsa049150.09212750

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »