

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | modulation by symbiont of host defense response (GO:0052031) | 6.09898371 |
| 2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.09898371 |
| 3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.09898371 |
| 4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.09898371 |
| 5 | modulation by symbiont of host immune response (GO:0052553) | 6.09898371 |
| 6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.09898371 |
| 7 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.52202808 |
| 8 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.45750231 |
| 9 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.31219713 |
| 10 | negative regulation of cell killing (GO:0031342) | 5.21927368 |
| 11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.21927368 |
| 12 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.88823197 |
| 13 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.75937764 |
| 14 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.68035484 |
| 15 | neutrophil activation involved in immune response (GO:0002283) | 4.59360598 |
| 16 | macrophage activation involved in immune response (GO:0002281) | 4.59026268 |
| 17 | B cell receptor signaling pathway (GO:0050853) | 4.57396842 |
| 18 | detection of other organism (GO:0098543) | 4.43541953 |
| 19 | detection of bacterium (GO:0016045) | 4.36847017 |
| 20 | immunoglobulin mediated immune response (GO:0016064) | 4.29952984 |
| 21 | response to host immune response (GO:0052572) | 4.26548722 |
| 22 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.26548722 |
| 23 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.25560888 |
| 24 | response to peptidoglycan (GO:0032494) | 4.24263636 |
| 25 | type I interferon signaling pathway (GO:0060337) | 4.03198164 |
| 26 | cellular response to type I interferon (GO:0071357) | 4.03198164 |
| 27 | response to type I interferon (GO:0034340) | 4.01567759 |
| 28 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.00723957 |
| 29 | positive regulation of B cell differentiation (GO:0045579) | 3.97694182 |
| 30 | microglial cell activation (GO:0001774) | 3.96426116 |
| 31 | regulation of B cell differentiation (GO:0045577) | 3.93172936 |
| 32 | detection of molecule of bacterial origin (GO:0032490) | 3.91424890 |
| 33 | negative regulation of interleukin-12 production (GO:0032695) | 3.91224175 |
| 34 | detection of external biotic stimulus (GO:0098581) | 3.89182823 |
| 35 | respiratory burst (GO:0045730) | 3.86188652 |
| 36 | response to host (GO:0075136) | 3.84846748 |
| 37 | response to host defenses (GO:0052200) | 3.84846748 |
| 38 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.84846748 |
| 39 | response to interleukin-15 (GO:0070672) | 3.84698697 |
| 40 | DNA deamination (GO:0045006) | 3.82958156 |
| 41 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.80461020 |
| 42 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.79072911 |
| 43 | cellular extravasation (GO:0045123) | 3.73908382 |
| 44 | regulation of gamma-delta T cell activation (GO:0046643) | 3.69449499 |
| 45 | cytidine deamination (GO:0009972) | 3.65225442 |
| 46 | cytidine metabolic process (GO:0046087) | 3.65225442 |
| 47 | cytidine catabolic process (GO:0006216) | 3.65225442 |
| 48 | negative regulation of type 2 immune response (GO:0002829) | 3.64909355 |
| 49 | leukocyte aggregation (GO:0070486) | 3.64686101 |
| 50 | cellular response to interleukin-15 (GO:0071350) | 3.57640153 |
| 51 | myeloid cell activation involved in immune response (GO:0002275) | 3.57586590 |
| 52 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.56363828 |
| 53 | neutrophil activation (GO:0042119) | 3.55772379 |
| 54 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.51557593 |
| 55 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.49378009 |
| 56 | B cell mediated immunity (GO:0019724) | 3.45499841 |
| 57 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.39147932 |
| 58 | negative regulation of B cell apoptotic process (GO:0002903) | 3.38730468 |
| 59 | detection of biotic stimulus (GO:0009595) | 3.37721730 |
| 60 | positive thymic T cell selection (GO:0045059) | 3.36741982 |
| 61 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.36438768 |
| 62 | neutrophil mediated immunity (GO:0002446) | 3.35665256 |
| 63 | negative regulation of T cell mediated immunity (GO:0002710) | 3.35548297 |
| 64 | negative regulation of phagocytosis (GO:0050765) | 3.32859734 |
| 65 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.30287038 |
| 66 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.22791231 |
| 67 | negative thymic T cell selection (GO:0045060) | 3.22713388 |
| 68 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.21829029 |
| 69 | macrophage activation (GO:0042116) | 3.21404831 |
| 70 | regulation of mast cell activation (GO:0033003) | 3.15934177 |
| 71 | regulation of mast cell degranulation (GO:0043304) | 3.15646867 |
| 72 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.12936732 |
| 73 | regulation of B cell apoptotic process (GO:0002902) | 3.12626703 |
| 74 | mature B cell differentiation involved in immune response (GO:0002313) | 3.11699794 |
| 75 | defense response to protozoan (GO:0042832) | 3.11317260 |
| 76 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.09418650 |
| 77 | T cell migration (GO:0072678) | 3.08515925 |
| 78 | regulation of antigen processing and presentation (GO:0002577) | 3.08057098 |
| 79 | granulocyte activation (GO:0036230) | 3.07264276 |
| 80 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.04401983 |
| 81 | negative T cell selection (GO:0043383) | 3.03950065 |
| 82 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.03020409 |
| 83 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.99974635 |
| 84 | positive T cell selection (GO:0043368) | 2.99745127 |
| 85 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.99343506 |
| 86 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.99343506 |
| 87 | positive regulation of interferon-alpha production (GO:0032727) | 2.99237587 |
| 88 | negative regulation of interleukin-6 production (GO:0032715) | 2.97446702 |
| 89 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.96855625 |
| 90 | germinal center formation (GO:0002467) | 2.95313650 |
| 91 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.94821524 |
| 92 | response to interferon-beta (GO:0035456) | 2.93052413 |
| 93 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.92766000 |
| 94 | negative regulation of interleukin-1 production (GO:0032692) | 2.91358524 |
| 95 | response to protozoan (GO:0001562) | 2.91346403 |
| 96 | T cell selection (GO:0045058) | 2.90523211 |
| 97 | leukocyte degranulation (GO:0043299) | 2.90317433 |
| 98 | positive regulation of mast cell activation (GO:0033005) | 2.82288895 |
| 99 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.80891465 |
| 100 | thymic T cell selection (GO:0045061) | 2.79863564 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.87241746 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.84845222 |
| 3 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.80478866 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.74368711 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.48400316 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.29801044 |
| 7 | VDR_24763502_ChIP-Seq_THP-1_Human | 3.19299354 |
| 8 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 3.07072031 |
| 9 | MYC_22102868_ChIP-Seq_BL_Human | 3.02536823 |
| 10 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.01407433 |
| 11 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.92691443 |
| 12 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.84858520 |
| 13 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.73356527 |
| 14 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.68855576 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.68643646 |
| 16 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.66242081 |
| 17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.61148279 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 2.58816994 |
| 19 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.53281489 |
| 20 | MAF_26560356_Chip-Seq_TH1_Human | 2.52767215 |
| 21 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.50370851 |
| 22 | UTX_26944678_Chip-Seq_JUKART_Human | 2.47403779 |
| 23 | SPI1_23127762_ChIP-Seq_K562_Human | 2.43541776 |
| 24 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.37162727 |
| 25 | MYB_26560356_Chip-Seq_TH1_Human | 2.20105468 |
| 26 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.15147267 |
| 27 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.14863347 |
| 28 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.13194785 |
| 29 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 2.05709304 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.01617524 |
| 31 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.00231865 |
| 32 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.97753299 |
| 33 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.93744452 |
| 34 | MAF_26560356_Chip-Seq_TH2_Human | 1.93320679 |
| 35 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.87880932 |
| 36 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.87327380 |
| 37 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.84128035 |
| 38 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.81628907 |
| 39 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.71822802 |
| 40 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.70874148 |
| 41 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.67878278 |
| 42 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.65972647 |
| 43 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.64108335 |
| 44 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.63023690 |
| 45 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.61509300 |
| 46 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.59736676 |
| 47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.56225771 |
| 48 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.55379360 |
| 49 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.54628873 |
| 50 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.50430022 |
| 51 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.48963650 |
| 52 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.48154622 |
| 53 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46843651 |
| 54 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.45266995 |
| 55 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.43895144 |
| 56 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.41221908 |
| 57 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.39946587 |
| 58 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.35001572 |
| 59 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.34852241 |
| 60 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31638838 |
| 61 | GATA3_26560356_Chip-Seq_TH2_Human | 1.30865808 |
| 62 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.30647241 |
| 63 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.30578979 |
| 64 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.29030935 |
| 65 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.26908424 |
| 66 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.25927131 |
| 67 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.24798227 |
| 68 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.24589328 |
| 69 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24558446 |
| 70 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24100197 |
| 71 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23794366 |
| 72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23020728 |
| 73 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20628508 |
| 74 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.20263858 |
| 75 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.20096204 |
| 76 | GATA1_19941826_ChIP-Seq_K562_Human | 1.19485086 |
| 77 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.18686966 |
| 78 | P300_27268052_Chip-Seq_Bcells_Human | 1.16551220 |
| 79 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.15817605 |
| 80 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15309328 |
| 81 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14704633 |
| 82 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14191746 |
| 83 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.10491924 |
| 84 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.10417678 |
| 85 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.09728966 |
| 86 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09461576 |
| 87 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08881763 |
| 88 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.05344711 |
| 89 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.02745301 |
| 90 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.01354683 |
| 91 | P68_20966046_ChIP-Seq_HELA_Human | 1.01117448 |
| 92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.99800348 |
| 93 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99124952 |
| 94 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.95516531 |
| 95 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.93091487 |
| 96 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92695428 |
| 97 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.92358035 |
| 98 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.90983044 |
| 99 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90762766 |
| 100 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89741279 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.94818506 |
| 2 | MP0003436_decreased_susceptibility_to | 3.93316392 |
| 3 | MP0003724_increased_susceptibility_to | 3.68576910 |
| 4 | MP0000685_abnormal_immune_system | 3.58754900 |
| 5 | MP0001800_abnormal_humoral_immune | 3.12981501 |
| 6 | MP0005451_abnormal_body_composition | 3.03691683 |
| 7 | MP0005671_abnormal_response_to | 2.98296085 |
| 8 | MP0002419_abnormal_innate_immunity | 2.96992419 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.95593545 |
| 10 | MP0005387_immune_system_phenotype | 2.95292343 |
| 11 | MP0001790_abnormal_immune_system | 2.95292343 |
| 12 | MP0003303_peritoneal_inflammation | 2.90481055 |
| 13 | MP0009278_abnormal_bone_marrow | 2.87075811 |
| 14 | MP0005025_abnormal_response_to | 2.85953448 |
| 15 | MP0002396_abnormal_hematopoietic_system | 2.76179497 |
| 16 | MP0002723_abnormal_immune_serum | 2.70204095 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.70151650 |
| 18 | MP0001819_abnormal_immune_cell | 2.66291661 |
| 19 | MP0009785_altered_susceptibility_to | 2.65500149 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.56597612 |
| 21 | MP0001545_abnormal_hematopoietic_system | 2.54869154 |
| 22 | MP0005397_hematopoietic_system_phenotyp | 2.54869154 |
| 23 | MP0008260_abnormal_autophagy | 2.42615876 |
| 24 | MP0003763_abnormal_thymus_physiology | 2.31135919 |
| 25 | MP0005464_abnormal_platelet_physiology | 2.24175690 |
| 26 | MP0002398_abnormal_bone_marrow | 2.21849354 |
| 27 | MP0000716_abnormal_immune_system | 2.10763474 |
| 28 | MP0002148_abnormal_hypersensitivity_rea | 2.05745075 |
| 29 | MP0003183_abnormal_peptide_metabolism | 1.93193686 |
| 30 | MP0000465_gastrointestinal_hemorrhage | 1.91592168 |
| 31 | MP0002405_respiratory_system_inflammati | 1.89876015 |
| 32 | MP0002722_abnormal_immune_system | 1.87570447 |
| 33 | MP0000689_abnormal_spleen_morphology | 1.84887327 |
| 34 | MP0002429_abnormal_blood_cell | 1.71430936 |
| 35 | MP0001533_abnormal_skeleton_physiology | 1.67440895 |
| 36 | MP0006082_CNS_inflammation | 1.65364392 |
| 37 | MP0005645_abnormal_hypothalamus_physiol | 1.63044950 |
| 38 | MP0001845_abnormal_inflammatory_respons | 1.61876768 |
| 39 | MP0003866_abnormal_defecation | 1.56588297 |
| 40 | MP0003300_gastrointestinal_ulcer | 1.54979562 |
| 41 | MP0010155_abnormal_intestine_physiology | 1.54956768 |
| 42 | MP0009764_decreased_sensitivity_to | 1.53973856 |
| 43 | MP0000703_abnormal_thymus_morphology | 1.52917982 |
| 44 | MP0005310_abnormal_salivary_gland | 1.49128063 |
| 45 | MP0005075_abnormal_melanosome_morpholog | 1.43040504 |
| 46 | MP0003191_abnormal_cellular_cholesterol | 1.41450272 |
| 47 | MP0003172_abnormal_lysosome_physiology | 1.38516904 |
| 48 | MP0001873_stomach_inflammation | 1.34829287 |
| 49 | MP0002166_altered_tumor_susceptibility | 1.34280633 |
| 50 | MP0004947_skin_inflammation | 1.27301284 |
| 51 | MP0002132_abnormal_respiratory_system | 1.26303054 |
| 52 | MP0003828_pulmonary_edema | 1.24714760 |
| 53 | MP0001986_abnormal_taste_sensitivity | 1.22699213 |
| 54 | MP0002822_catalepsy | 1.22366910 |
| 55 | MP0004381_abnormal_hair_follicle | 1.21436810 |
| 56 | MP0008469_abnormal_protein_level | 1.19920286 |
| 57 | MP0000858_altered_metastatic_potential | 1.16744413 |
| 58 | MP0009333_abnormal_splenocyte_physiolog | 1.12194989 |
| 59 | MP0000015_abnormal_ear_pigmentation | 1.07032224 |
| 60 | MP0003252_abnormal_bile_duct | 1.04580141 |
| 61 | MP0004808_abnormal_hematopoietic_stem | 1.03430055 |
| 62 | MP0000569_abnormal_digit_pigmentation | 0.94306090 |
| 63 | MP0000490_abnormal_crypts_of | 0.93541464 |
| 64 | MP0002006_tumorigenesis | 0.92463980 |
| 65 | MP0009765_abnormal_xenobiotic_induced | 0.88552006 |
| 66 | MP0008874_decreased_physiological_sensi | 0.86348215 |
| 67 | MP0006035_abnormal_mitochondrial_morpho | 0.83256458 |
| 68 | MP0004883_abnormal_blood_vessel | 0.82762171 |
| 69 | MP0002019_abnormal_tumor_incidence | 0.81224948 |
| 70 | MP0008873_increased_physiological_sensi | 0.78264719 |
| 71 | MP0009763_increased_sensitivity_to | 0.76611696 |
| 72 | MP0001663_abnormal_digestive_system | 0.75422496 |
| 73 | MP0003075_altered_response_to | 0.72250882 |
| 74 | MP0002277_abnormal_respiratory_mucosa | 0.67577692 |
| 75 | MP0001851_eye_inflammation | 0.66799056 |
| 76 | MP0005084_abnormal_gallbladder_morpholo | 0.63755095 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.60457782 |
| 78 | MP0002653_abnormal_ependyma_morphology | 0.56486785 |
| 79 | MP0008961_abnormal_basal_metabolism | 0.56093746 |
| 80 | MP0005166_decreased_susceptibility_to | 0.54753330 |
| 81 | MP0005390_skeleton_phenotype | 0.54530222 |
| 82 | MP0005164_abnormal_response_to | 0.51872836 |
| 83 | MP0000604_amyloidosis | 0.48280279 |
| 84 | MP0008872_abnormal_physiological_respon | 0.47878421 |
| 85 | MP0003806_abnormal_nucleotide_metabolis | 0.47607333 |
| 86 | MP0002998_abnormal_bone_remodeling | 0.46507965 |
| 87 | MP0000470_abnormal_stomach_morphology | 0.42302366 |
| 88 | MP0003221_abnormal_cardiomyocyte_apopto | 0.42213402 |
| 89 | MP0005535_abnormal_body_temperature | 0.42162925 |
| 90 | MP0002928_abnormal_bile_duct | 0.39970504 |
| 91 | MP0005367_renal/urinary_system_phenotyp | 0.39387585 |
| 92 | MP0000516_abnormal_urinary_system | 0.39387585 |
| 93 | MP0008004_abnormal_stomach_pH | 0.38561363 |
| 94 | MP0005621_abnormal_cell_physiology | 0.38434419 |
| 95 | MP0003638_abnormal_response/metabolism_ | 0.38383815 |
| 96 | MP0001968_abnormal_touch/_nociception | 0.37879804 |
| 97 | MP0001853_heart_inflammation | 0.37475262 |
| 98 | MP0003011_delayed_dark_adaptation | 0.37104848 |
| 99 | MP0004742_abnormal_vestibular_system | 0.37006041 |
| 100 | MP0000371_diluted_coat_color | 0.36960057 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent abscess formation (HP:0002722) | 5.54636689 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.41210337 |
| 3 | Myositis (HP:0100614) | 5.39151094 |
| 4 | Eczematoid dermatitis (HP:0000976) | 5.01186602 |
| 5 | Recurrent bacterial skin infections (HP:0005406) | 4.99375820 |
| 6 | Agammaglobulinemia (HP:0004432) | 4.71503292 |
| 7 | Meningitis (HP:0001287) | 4.63192230 |
| 8 | Recurrent fungal infections (HP:0002841) | 4.60215707 |
| 9 | Stomatitis (HP:0010280) | 4.59896594 |
| 10 | Obstructive lung disease (HP:0006536) | 4.55150984 |
| 11 | Chronic obstructive pulmonary disease (HP:0006510) | 4.55150984 |
| 12 | Mediastinal lymphadenopathy (HP:0100721) | 4.53831001 |
| 13 | Orchitis (HP:0100796) | 4.51467295 |
| 14 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.47475547 |
| 15 | Recurrent cutaneous fungal infections (HP:0011370) | 4.47475547 |
| 16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.42720408 |
| 17 | Retrobulbar optic neuritis (HP:0100654) | 4.26019259 |
| 18 | Optic neuritis (HP:0100653) | 4.26019259 |
| 19 | Abnormality of macrophages (HP:0004311) | 4.25126810 |
| 20 | Increased IgE level (HP:0003212) | 4.21123127 |
| 21 | Encephalitis (HP:0002383) | 3.92779187 |
| 22 | Cellulitis (HP:0100658) | 3.89552430 |
| 23 | Recurrent skin infections (HP:0001581) | 3.86995185 |
| 24 | Panhypogammaglobulinemia (HP:0003139) | 3.68989313 |
| 25 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.62281262 |
| 26 | Vasculitis (HP:0002633) | 3.45940405 |
| 27 | Gastrointestinal inflammation (HP:0004386) | 3.45807012 |
| 28 | Inflammation of the large intestine (HP:0002037) | 3.39841072 |
| 29 | Urticaria (HP:0001025) | 3.36751288 |
| 30 | Chest pain (HP:0100749) | 3.36395676 |
| 31 | Gastrointestinal infarctions (HP:0005244) | 3.34235214 |
| 32 | Colitis (HP:0002583) | 3.30238638 |
| 33 | Prolonged bleeding time (HP:0003010) | 3.29212872 |
| 34 | Hypochromic microcytic anemia (HP:0004840) | 3.28719289 |
| 35 | B lymphocytopenia (HP:0010976) | 3.17494444 |
| 36 | Recurrent viral infections (HP:0004429) | 3.15750373 |
| 37 | Keratoconjunctivitis (HP:0001096) | 3.13823735 |
| 38 | Keratoconjunctivitis sicca (HP:0001097) | 3.04725002 |
| 39 | Abnormality of B cell number (HP:0010975) | 3.04192418 |
| 40 | Gingivitis (HP:0000230) | 2.94985120 |
| 41 | Sepsis (HP:0100806) | 2.94184202 |
| 42 | Recurrent sinusitis (HP:0011108) | 2.93661249 |
| 43 | Osteomyelitis (HP:0002754) | 2.92211720 |
| 44 | IgM deficiency (HP:0002850) | 2.87938957 |
| 45 | Granulocytopenia (HP:0001913) | 2.83150003 |
| 46 | Abnormality of T cell physiology (HP:0011840) | 2.83011106 |
| 47 | Arterial thrombosis (HP:0004420) | 2.79845569 |
| 48 | Episodic fever (HP:0001954) | 2.79203120 |
| 49 | Lymphopenia (HP:0001888) | 2.76834469 |
| 50 | Hypergammaglobulinemia (HP:0010702) | 2.74402675 |
| 51 | Epistaxis (HP:0000421) | 2.72628529 |
| 52 | Gastrointestinal stroma tumor (HP:0100723) | 2.66046410 |
| 53 | Hypochromic anemia (HP:0001931) | 2.64949100 |
| 54 | Leukocytosis (HP:0001974) | 2.64779726 |
| 55 | Recurrent pneumonia (HP:0006532) | 2.53860954 |
| 56 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.53552476 |
| 57 | Gingival bleeding (HP:0000225) | 2.51299448 |
| 58 | Hemoptysis (HP:0002105) | 2.49589891 |
| 59 | Recurrent lower respiratory tract infections (HP:0002783) | 2.44981828 |
| 60 | Spontaneous hematomas (HP:0007420) | 2.43735489 |
| 61 | Chronic otitis media (HP:0000389) | 2.41753935 |
| 62 | Viral hepatitis (HP:0006562) | 2.40318916 |
| 63 | Acute hepatic failure (HP:0006554) | 2.39527879 |
| 64 | Abnormality of T cells (HP:0002843) | 2.39478512 |
| 65 | Petechiae (HP:0000967) | 2.37416363 |
| 66 | Thrombocytosis (HP:0001894) | 2.36387656 |
| 67 | Pulmonary infiltrates (HP:0002113) | 2.34174364 |
| 68 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.33823704 |
| 69 | Prostate neoplasm (HP:0100787) | 2.33480408 |
| 70 | Skin rash (HP:0000988) | 2.30960757 |
| 71 | Anorexia (HP:0002039) | 2.30433105 |
| 72 | Abnormality of the pleura (HP:0002103) | 2.29392261 |
| 73 | Papilloma (HP:0012740) | 2.28381737 |
| 74 | Verrucae (HP:0200043) | 2.28381737 |
| 75 | Hypertensive crisis (HP:0100735) | 2.26050208 |
| 76 | Abnormality of the prostate (HP:0008775) | 2.24634879 |
| 77 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.24595975 |
| 78 | Keratitis (HP:0000491) | 2.22024119 |
| 79 | Peritonitis (HP:0002586) | 2.21005196 |
| 80 | Skin ulcer (HP:0200042) | 2.19397340 |
| 81 | Autoimmune hemolytic anemia (HP:0001890) | 2.16592450 |
| 82 | Eosinophilia (HP:0001880) | 2.16132907 |
| 83 | Abnormality of the peritoneum (HP:0002585) | 2.13505287 |
| 84 | Slow saccadic eye movements (HP:0000514) | 2.13241559 |
| 85 | Loss of speech (HP:0002371) | 2.11121080 |
| 86 | IgG deficiency (HP:0004315) | 2.07750978 |
| 87 | Abnormality of the endocardium (HP:0004306) | 2.01985321 |
| 88 | Increased IgM level (HP:0003496) | 2.01924655 |
| 89 | Pustule (HP:0200039) | 1.99457336 |
| 90 | Acne (HP:0001061) | 1.92796037 |
| 91 | Autoimmune thrombocytopenia (HP:0001973) | 1.92657805 |
| 92 | Microcytic anemia (HP:0001935) | 1.92189750 |
| 93 | Pulmonary embolism (HP:0002204) | 1.90681827 |
| 94 | Recurrent bronchitis (HP:0002837) | 1.90644640 |
| 95 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.89125409 |
| 96 | Purpura (HP:0000979) | 1.88855553 |
| 97 | Gangrene (HP:0100758) | 1.83758153 |
| 98 | Severe visual impairment (HP:0001141) | 1.83735423 |
| 99 | Vertigo (HP:0002321) | 1.83407083 |
| 100 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.80945827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 4.83659198 |
| 2 | RIPK4 | 4.59465369 |
| 3 | GRK6 | 3.05616312 |
| 4 | BCKDK | 2.95544349 |
| 5 | TESK2 | 2.90642316 |
| 6 | KIT | 2.85930160 |
| 7 | BLK | 2.72641656 |
| 8 | TNK2 | 2.54548788 |
| 9 | CDK19 | 2.40771947 |
| 10 | ERN1 | 2.33607425 |
| 11 | TAOK3 | 2.30597738 |
| 12 | IRAK4 | 2.24024182 |
| 13 | MAP3K11 | 2.13507122 |
| 14 | MAP2K3 | 2.04149805 |
| 15 | SYK | 1.95063487 |
| 16 | PRPF4B | 1.90043998 |
| 17 | TAOK1 | 1.89016751 |
| 18 | BTK | 1.87542680 |
| 19 | JAK3 | 1.85807301 |
| 20 | TYK2 | 1.85331033 |
| 21 | VRK2 | 1.84676992 |
| 22 | CSF1R | 1.81215359 |
| 23 | SMG1 | 1.75234203 |
| 24 | SIK2 | 1.75160959 |
| 25 | FES | 1.74379283 |
| 26 | CSK | 1.57964385 |
| 27 | PIM2 | 1.56563657 |
| 28 | TBK1 | 1.53124147 |
| 29 | LYN | 1.49484488 |
| 30 | KDR | 1.47319397 |
| 31 | SCYL2 | 1.46681943 |
| 32 | SIK3 | 1.27911395 |
| 33 | TAOK2 | 1.23614772 |
| 34 | IKBKE | 1.22849757 |
| 35 | MAP3K3 | 1.22383247 |
| 36 | HCK | 1.21919964 |
| 37 | MAP3K14 | 1.13888747 |
| 38 | MATK | 1.11653142 |
| 39 | LCK | 1.06578793 |
| 40 | FGR | 1.04457872 |
| 41 | IKBKB | 1.01494026 |
| 42 | MAP3K1 | 0.99823410 |
| 43 | JAK2 | 0.99163034 |
| 44 | TEC | 0.96059470 |
| 45 | DYRK1B | 0.94159603 |
| 46 | PRKD2 | 0.87477018 |
| 47 | MAP3K13 | 0.86264201 |
| 48 | TXK | 0.83176973 |
| 49 | HIPK2 | 0.82749068 |
| 50 | ZAP70 | 0.81964570 |
| 51 | BMPR2 | 0.76823575 |
| 52 | PIK3CG | 0.76369356 |
| 53 | PTK2B | 0.73817102 |
| 54 | JAK1 | 0.73781723 |
| 55 | ITK | 0.73033462 |
| 56 | MAP3K7 | 0.72548976 |
| 57 | MAP3K5 | 0.68577985 |
| 58 | FLT3 | 0.67000529 |
| 59 | MARK2 | 0.66236944 |
| 60 | TAF1 | 0.65789584 |
| 61 | PDK1 | 0.64033901 |
| 62 | NUAK1 | 0.63469291 |
| 63 | PRKCQ | 0.61445461 |
| 64 | GRK5 | 0.59754767 |
| 65 | EPHB1 | 0.59629819 |
| 66 | OXSR1 | 0.59125859 |
| 67 | TESK1 | 0.58358141 |
| 68 | PIM1 | 0.56755063 |
| 69 | IRAK1 | 0.55565151 |
| 70 | YES1 | 0.50694677 |
| 71 | KSR2 | 0.49724895 |
| 72 | FYN | 0.47844008 |
| 73 | FRK | 0.46105633 |
| 74 | RAF1 | 0.45582726 |
| 75 | MARK3 | 0.43578207 |
| 76 | PRKCH | 0.43558346 |
| 77 | DAPK1 | 0.42531732 |
| 78 | NME2 | 0.42111431 |
| 79 | ZAK | 0.42035283 |
| 80 | DYRK3 | 0.40625744 |
| 81 | VRK1 | 0.36078745 |
| 82 | MAPKAPK2 | 0.35728240 |
| 83 | TRIB3 | 0.33240300 |
| 84 | CCNB1 | 0.32583736 |
| 85 | MAP3K6 | 0.32257177 |
| 86 | ARAF | 0.30762814 |
| 87 | PDPK1 | 0.27463356 |
| 88 | MAP3K2 | 0.27340549 |
| 89 | MAP4K2 | 0.26731321 |
| 90 | PRKCD | 0.26481664 |
| 91 | MAPK7 | 0.26395323 |
| 92 | STK10 | 0.24672773 |
| 93 | PRKCZ | 0.24031955 |
| 94 | MAPK4 | 0.23613056 |
| 95 | LRRK2 | 0.22956933 |
| 96 | ABL1 | 0.22128015 |
| 97 | IRAK2 | 0.22120289 |
| 98 | STK11 | 0.21700343 |
| 99 | MAPK12 | 0.20589608 |
| 100 | PRKD1 | 0.18901164 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.80002425 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.15960369 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.06200835 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.92758110 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.86702506 |
| 6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.70294403 |
| 7 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.40704319 |
| 8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.39017078 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.25122326 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.21681399 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.20028957 |
| 12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.12297887 |
| 13 | Tuberculosis_Homo sapiens_hsa05152 | 2.10309671 |
| 14 | Viral myocarditis_Homo sapiens_hsa05416 | 2.07795712 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.05641581 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.05534658 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.94416797 |
| 18 | Measles_Homo sapiens_hsa05162 | 1.86395736 |
| 19 | Influenza A_Homo sapiens_hsa05164 | 1.77906578 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.75285644 |
| 21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.70722481 |
| 22 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.69037816 |
| 23 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.67987473 |
| 24 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.60721163 |
| 25 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.49828030 |
| 26 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.49477795 |
| 27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.48253342 |
| 28 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.43805382 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.42049973 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.41628996 |
| 31 | Phagosome_Homo sapiens_hsa04145 | 1.32841148 |
| 32 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.26990842 |
| 33 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.24438884 |
| 34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.21284470 |
| 35 | Hepatitis C_Homo sapiens_hsa05160 | 1.19667821 |
| 36 | Platelet activation_Homo sapiens_hsa04611 | 1.19072971 |
| 37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.18452150 |
| 38 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.15022711 |
| 39 | Shigellosis_Homo sapiens_hsa05131 | 1.12716988 |
| 40 | Legionellosis_Homo sapiens_hsa05134 | 1.09947351 |
| 41 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.06897081 |
| 42 | Malaria_Homo sapiens_hsa05144 | 1.06324591 |
| 43 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.05849700 |
| 44 | Hepatitis B_Homo sapiens_hsa05161 | 1.04103964 |
| 45 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.01173171 |
| 46 | Apoptosis_Homo sapiens_hsa04210 | 0.97836825 |
| 47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.94930881 |
| 48 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.92717900 |
| 49 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.92223811 |
| 50 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.92218634 |
| 51 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.91991886 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.91601302 |
| 53 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88271520 |
| 54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.88085151 |
| 55 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.81551666 |
| 56 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.78036315 |
| 57 | Endocytosis_Homo sapiens_hsa04144 | 0.77574278 |
| 58 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.77047528 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.75064865 |
| 60 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.74182843 |
| 61 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71273326 |
| 62 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70504964 |
| 63 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65436504 |
| 64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.64676527 |
| 65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.63672575 |
| 66 | HTLV-I infection_Homo sapiens_hsa05166 | 0.62372154 |
| 67 | Salmonella infection_Homo sapiens_hsa05132 | 0.57107894 |
| 68 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.54474435 |
| 69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54361922 |
| 70 | Base excision repair_Homo sapiens_hsa03410 | 0.54111860 |
| 71 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.53613619 |
| 72 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.53314781 |
| 73 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.51879079 |
| 74 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.49751505 |
| 75 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.47994410 |
| 76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.47386509 |
| 77 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.46186472 |
| 78 | Pertussis_Homo sapiens_hsa05133 | 0.44993864 |
| 79 | Other glycan degradation_Homo sapiens_hsa00511 | 0.44240211 |
| 80 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.43302755 |
| 81 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42201772 |
| 82 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40441793 |
| 83 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.40325013 |
| 84 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.40207171 |
| 85 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.38967524 |
| 86 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.37559281 |
| 87 | Endometrial cancer_Homo sapiens_hsa05213 | 0.37143995 |
| 88 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.36949386 |
| 89 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.33608244 |
| 90 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.33220593 |
| 91 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.33173423 |
| 92 | Alcoholism_Homo sapiens_hsa05034 | 0.33129682 |
| 93 | Lysosome_Homo sapiens_hsa04142 | 0.30334829 |
| 94 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.28731099 |
| 95 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.27499594 |
| 96 | Glioma_Homo sapiens_hsa05214 | 0.25689565 |
| 97 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.24679369 |
| 98 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.22934098 |
| 99 | Colorectal cancer_Homo sapiens_hsa05210 | 0.22726259 |
| 100 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.20950124 |

