DYNC1LI2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.22279966
2regulation of short-term neuronal synaptic plasticity (GO:0048172)4.97961917
3locomotory exploration behavior (GO:0035641)4.65438229
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.64291660
5synaptic vesicle exocytosis (GO:0016079)4.45396861
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.35934217
7vocalization behavior (GO:0071625)4.34474698
8glutamate secretion (GO:0014047)4.20919581
9neuronal action potential propagation (GO:0019227)4.12240396
10layer formation in cerebral cortex (GO:0021819)4.10753053
11regulation of synaptic vesicle exocytosis (GO:2000300)4.10666509
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.08536554
13exploration behavior (GO:0035640)3.87397570
14synaptic vesicle docking involved in exocytosis (GO:0016081)3.87104233
15regulation of synapse structural plasticity (GO:0051823)3.75037432
16regulation of glutamate receptor signaling pathway (GO:1900449)3.73028862
17neurotransmitter secretion (GO:0007269)3.68833122
18ionotropic glutamate receptor signaling pathway (GO:0035235)3.65949263
19neuron cell-cell adhesion (GO:0007158)3.65353683
20cellular potassium ion homeostasis (GO:0030007)3.64441453
21protein localization to synapse (GO:0035418)3.63812539
22postsynaptic membrane organization (GO:0001941)3.60965211
23membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.59139456
24regulation of neuronal synaptic plasticity (GO:0048168)3.58183621
25dendritic spine morphogenesis (GO:0060997)3.55971451
26regulation of synaptic vesicle transport (GO:1902803)3.55479765
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.52990407
28central nervous system myelination (GO:0022010)3.42580286
29axon ensheathment in central nervous system (GO:0032291)3.42580286
30presynaptic membrane assembly (GO:0097105)3.40806431
31regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.38208251
32sodium ion export (GO:0071436)3.38031476
33neuron recognition (GO:0008038)3.34245019
34presynaptic membrane organization (GO:0097090)3.34148241
35glutamate receptor signaling pathway (GO:0007215)3.29594474
36activation of protein kinase A activity (GO:0034199)3.27824005
37dendrite morphogenesis (GO:0048813)3.27262992
38gamma-aminobutyric acid transport (GO:0015812)3.22883112
39synaptic transmission, glutamatergic (GO:0035249)3.22801632
40cerebellar Purkinje cell differentiation (GO:0021702)3.22416677
41positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.20165906
42neuron-neuron synaptic transmission (GO:0007270)3.20131379
43regulation of dendritic spine morphogenesis (GO:0061001)3.19435672
44neuromuscular process controlling balance (GO:0050885)3.17802884
45axonal fasciculation (GO:0007413)3.15632081
46proline transport (GO:0015824)3.14425476
47regulation of excitatory postsynaptic membrane potential (GO:0060079)3.11701076
48mating behavior (GO:0007617)3.08242818
49long-term memory (GO:0007616)3.07637439
50transmission of nerve impulse (GO:0019226)3.05733050
51regulation of postsynaptic membrane potential (GO:0060078)3.05623323
52glycine transport (GO:0015816)3.03004304
53prepulse inhibition (GO:0060134)3.01355545
54neurotransmitter transport (GO:0006836)3.01015078
55vesicle transport along microtubule (GO:0047496)3.00747901
56membrane depolarization during action potential (GO:0086010)2.99724147
57cell migration in hindbrain (GO:0021535)2.99249935
58cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.97973976
59membrane hyperpolarization (GO:0060081)2.92460357
60regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.92356097
61cell communication by electrical coupling (GO:0010644)2.90992579
62cytoskeletal anchoring at plasma membrane (GO:0007016)2.90302740
63neuronal ion channel clustering (GO:0045161)2.89612210
64establishment of nucleus localization (GO:0040023)2.87524794
65potassium ion import (GO:0010107)2.87105178
66regulation of synaptic plasticity (GO:0048167)2.86861961
67positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.86595206
68organelle transport along microtubule (GO:0072384)2.82207792
69regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.81869066
70membrane depolarization (GO:0051899)2.81071700
71apical protein localization (GO:0045176)2.80532532
72positive regulation of membrane potential (GO:0045838)2.80364967
73gamma-aminobutyric acid signaling pathway (GO:0007214)2.80060115
74regulation of neurotransmitter secretion (GO:0046928)2.79862288
75regulation of voltage-gated calcium channel activity (GO:1901385)2.78013902
76regulation of neurotransmitter levels (GO:0001505)2.77859052
77regulation of vesicle fusion (GO:0031338)2.77324112
78positive regulation of dendritic spine morphogenesis (GO:0061003)2.76627299
79negative regulation of synaptic transmission, GABAergic (GO:0032229)2.75784754
80regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.75726688
81neuromuscular process controlling posture (GO:0050884)2.75351751
82axon extension (GO:0048675)2.74087191
83long-term synaptic potentiation (GO:0060291)2.73529216
84auditory behavior (GO:0031223)2.73379210
85L-amino acid import (GO:0043092)2.73260080
86positive regulation of potassium ion transmembrane transport (GO:1901381)2.73151002
87innervation (GO:0060384)2.71918106
88regulation of synaptic transmission, glutamatergic (GO:0051966)2.71779229
89synaptic vesicle endocytosis (GO:0048488)2.71194681
90regulation of dendritic spine development (GO:0060998)2.71121023
91neurotransmitter-gated ion channel clustering (GO:0072578)2.70950996
92cellular sodium ion homeostasis (GO:0006883)2.70153625
93membrane assembly (GO:0071709)2.69050673
94positive regulation of potassium ion transport (GO:0043268)2.68527446
95amino acid import (GO:0043090)2.68236944
96potassium ion homeostasis (GO:0055075)2.67743765
97adult walking behavior (GO:0007628)2.67173829
98positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.67034307
99cerebellar granule cell differentiation (GO:0021707)2.66749335
100regulation of neurotransmitter transport (GO:0051588)2.65321397
101dendritic spine organization (GO:0097061)2.62536476
102response to auditory stimulus (GO:0010996)2.61849460
103negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.59524321
104positive regulation of synapse maturation (GO:0090129)2.59418554
105myelination in peripheral nervous system (GO:0022011)2.59038958
106peripheral nervous system axon ensheathment (GO:0032292)2.59038958
107synapse organization (GO:0050808)2.58703525
108neuromuscular process (GO:0050905)2.58646169
109positive regulation of synaptic transmission, GABAergic (GO:0032230)2.58258717
110synapse assembly (GO:0007416)2.56791035
111establishment of mitochondrion localization (GO:0051654)2.56686865
112camera-type eye morphogenesis (GO:0048593)2.51213847
113regulation of axon extension involved in axon guidance (GO:0048841)2.49839866
114suckling behavior (GO:0001967)2.49255017
115positive regulation of dendritic spine development (GO:0060999)2.48468782
116axon cargo transport (GO:0008088)2.47655014
117cell communication involved in cardiac conduction (GO:0086065)2.47079417
118embryonic retina morphogenesis in camera-type eye (GO:0060059)2.45095711
119neuron projection extension (GO:1990138)2.44301229
120pyrimidine nucleobase catabolic process (GO:0006208)2.43073605
121regulation of axon guidance (GO:1902667)2.42123498
122cerebellar Purkinje cell layer development (GO:0021680)2.41847568
123positive regulation of synapse assembly (GO:0051965)2.37986368
124cerebral cortex radially oriented cell migration (GO:0021799)2.37186139
125neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.35639867
126paraxial mesoderm development (GO:0048339)2.34569083
127astrocyte development (GO:0014002)2.33780451
128cell-cell junction maintenance (GO:0045217)2.31579737
129neuron remodeling (GO:0016322)2.27817274
130developmental cell growth (GO:0048588)2.26180078
131myelination (GO:0042552)2.24587762
132regulation of NFAT protein import into nucleus (GO:0051532)2.22560065
133central nervous system projection neuron axonogenesis (GO:0021952)2.21419289
134clathrin coat assembly (GO:0048268)2.20875036
135asymmetric protein localization (GO:0008105)2.18427951
136axon ensheathment (GO:0008366)2.18052272
137ensheathment of neurons (GO:0007272)2.18052272
138negative regulation of dendrite morphogenesis (GO:0050774)2.16852858
139regulation of ARF protein signal transduction (GO:0032012)2.16147344
140establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.14965338
141mitochondrion transport along microtubule (GO:0047497)2.14965338
142regulation of synapse assembly (GO:0051963)2.13926632
143regulation of synapse maturation (GO:0090128)2.13513145
144cellular response to catecholamine stimulus (GO:0071870)2.13440813
145cellular response to monoamine stimulus (GO:0071868)2.13440813

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.78370589
2GBX2_23144817_ChIP-Seq_PC3_Human2.88755165
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.88302186
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85344657
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.71279205
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.65630076
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.65630076
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.41460380
9MTF2_20144788_ChIP-Seq_MESCs_Mouse2.41405151
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.40701435
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40411102
12DROSHA_22980978_ChIP-Seq_HELA_Human2.38652961
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.36442478
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.32829832
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.29377253
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.22029736
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.20159314
18RARB_27405468_Chip-Seq_BRAIN_Mouse2.18208114
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09700411
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.09233297
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.04019585
22REST_21632747_ChIP-Seq_MESCs_Mouse2.03984625
23IKZF1_21737484_ChIP-ChIP_HCT116_Human1.92750806
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.84646377
25AR_21572438_ChIP-Seq_LNCaP_Human1.74063928
26SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.70895235
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.69656081
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.68928745
29TP63_17297297_ChIP-ChIP_HaCaT_Human1.67895159
30WT1_19549856_ChIP-ChIP_CCG9911_Human1.65999681
31REST_18959480_ChIP-ChIP_MESCs_Mouse1.64717006
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.63351023
33CDX2_19796622_ChIP-Seq_MESCs_Mouse1.63271168
34CLOCK_20551151_ChIP-Seq_293T_Human1.59478366
35ERG_21242973_ChIP-ChIP_JURKAT_Human1.47762672
36NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.46626717
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.46023142
38CTNNB1_20460455_ChIP-Seq_HCT116_Human1.45747517
39SMAD4_21799915_ChIP-Seq_A2780_Human1.44277404
40ZNF274_21170338_ChIP-Seq_K562_Hela1.44103489
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.43223503
42* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37837737
43SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.37761838
44TAF15_26573619_Chip-Seq_HEK293_Human1.36375636
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35370085
46PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34696071
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33972502
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32917170
49ZFP281_27345836_Chip-Seq_ESCs_Mouse1.32692488
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.32135573
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.31921104
52* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.31759198
53WT1_25993318_ChIP-Seq_PODOCYTE_Human1.31034986
54SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.30577615
55OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30550650
56DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.29437901
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.26928850
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25855428
59TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25394757
60NFIB_24661679_ChIP-Seq_LUNG_Mouse1.23874486
61AHR_22903824_ChIP-Seq_MCF-7_Human1.23354935
62ISL1_27105846_Chip-Seq_CPCs_Mouse1.23097266
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.22829500
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.22757837
65OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21884937
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.21401927
67RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.21350356
68EP300_21415370_ChIP-Seq_HL-1_Mouse1.19769902
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.19767744
70ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.19383634
71STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19239637
72KDM2B_26808549_Chip-Seq_K562_Human1.17957184
73SMAD_19615063_ChIP-ChIP_OVARY_Human1.16042118
74PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.14442348
75STAT3_23295773_ChIP-Seq_U87_Human1.14173796
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.14088992
77AR_19668381_ChIP-Seq_PC3_Human1.13807583
78THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.13733825
79RING1B_27294783_Chip-Seq_NPCs_Mouse1.13528424
80TP53_16413492_ChIP-PET_HCT116_Human1.10744720
81P300_19829295_ChIP-Seq_ESCs_Human1.10130119
82TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09989484
83TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.08940070
84CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08647443
85AR_25329375_ChIP-Seq_VCAP_Human1.07882566
86ZFP57_27257070_Chip-Seq_ESCs_Mouse1.07205654
87AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.05652677
88SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04566040
89* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.02153752
90YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01718107
91ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00033537
92NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.99812257
93EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.99587992
94TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99450263
95TRIM28_21343339_ChIP-Seq_HEK293_Human0.98665032
96DNAJC2_21179169_ChIP-ChIP_NT2_Human0.97941032
97TP53_20018659_ChIP-ChIP_R1E_Mouse0.97683305
98SMAD4_21741376_ChIP-Seq_HESCs_Human0.97321699
99ESR1_20079471_ChIP-ChIP_T-47D_Human0.96979181
100* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96675743
101RNF2_27304074_Chip-Seq_NSC_Mouse0.96608864
102P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96312552
103SMAD3_21741376_ChIP-Seq_HESCs_Human0.95790869
104TCF4_18268006_ChIP-ChIP_LS174T_Human0.95492856
105SOX9_26525672_Chip-Seq_HEART_Mouse0.95417492
106TBX3_20139965_ChIP-Seq_MESCs_Mouse0.94806411
107VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94777977
108TCF4_23295773_ChIP-Seq_U87_Human0.94738850
109RXR_22108803_ChIP-Seq_LS180_Human0.94512674
110BMI1_23680149_ChIP-Seq_NPCS_Mouse0.94447191
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93810301
112SMAD3_21741376_ChIP-Seq_ESCs_Human0.93597387
113TBX3_20139965_ChIP-Seq_ESCs_Mouse0.93142316
114RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93073857
115NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92557684
116NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.92506366
117NRF2_20460467_ChIP-Seq_MEFs_Mouse0.92351066
118NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.92351066
119ESR2_21235772_ChIP-Seq_MCF-7_Human0.92312333
120TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.92113856
121TP53_18474530_ChIP-ChIP_U2OS_Human0.92058770
122FOXA2_19822575_ChIP-Seq_HepG2_Human0.91903987
123GATA1_26923725_Chip-Seq_HPCs_Mouse0.91797243
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91434185
125TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90750567
126BCAT_22108803_ChIP-Seq_LS180_Human0.89240561
127RUNX2_22187159_ChIP-Seq_PCA_Human0.89014321
128BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.88942721
129TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87695645
130UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.85208366

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.73918166
2MP0003880_abnormal_central_pattern4.15978502
3MP0004270_analgesia3.78723967
4MP0003635_abnormal_synaptic_transmissio3.66837183
5MP0009745_abnormal_behavioral_response2.93029331
6MP0001968_abnormal_touch/_nociception2.91426003
7MP0009046_muscle_twitch2.87190731
8MP0002064_seizures2.82998475
9MP0002063_abnormal_learning/memory/cond2.81494157
10MP0002734_abnormal_mechanical_nocicepti2.62923863
11MP0002272_abnormal_nervous_system2.49343132
12MP0001486_abnormal_startle_reflex2.38684861
13MP0002822_catalepsy2.34307947
14MP0002572_abnormal_emotion/affect_behav2.33319142
15MP0002736_abnormal_nociception_after2.32118528
16MP0005423_abnormal_somatic_nervous2.29621820
17MP0001440_abnormal_grooming_behavior2.06857407
18MP0002735_abnormal_chemical_nociception2.06172314
19MP0002733_abnormal_thermal_nociception2.00363570
20MP0003705_abnormal_hypodermis_morpholog1.97184526
21MP0001970_abnormal_pain_threshold1.96670234
22MP0003329_amyloid_beta_deposits1.95555453
23MP0000566_synostosis1.91467620
24MP0008569_lethality_at_weaning1.89636788
25MP0002067_abnormal_sensory_capabilities1.87929502
26MP0004858_abnormal_nervous_system1.87098763
27MP0009780_abnormal_chondrocyte_physiolo1.86260992
28MP0000778_abnormal_nervous_system1.85879296
29MP0001501_abnormal_sleep_pattern1.77784999
30MP0004885_abnormal_endolymph1.75003495
31MP0002184_abnormal_innervation1.71272735
32MP0004811_abnormal_neuron_physiology1.68005653
33MP0005623_abnormal_meninges_morphology1.62905298
34MP0004272_abnormal_basement_membrane1.62833008
35MP0000751_myopathy1.61488556
36MP0000955_abnormal_spinal_cord1.59420659
37MP0002909_abnormal_adrenal_gland1.58119326
38MP0004924_abnormal_behavior1.57515394
39MP0005386_behavior/neurological_phenoty1.57515394
40MP0005503_abnormal_tendon_morphology1.56058596
41MP0000920_abnormal_myelination1.51402864
42MP0002557_abnormal_social/conspecific_i1.46356423
43MP0002882_abnormal_neuron_morphology1.40046950
44MP0003633_abnormal_nervous_system1.39157548
45MP0001188_hyperpigmentation1.35445559
46MP0002066_abnormal_motor_capabilities/c1.34958148
47MP0004145_abnormal_muscle_electrophysio1.34133845
48MP0000579_abnormal_nail_morphology1.33837793
49MP0006276_abnormal_autonomic_nervous1.32684241
50MP0000013_abnormal_adipose_tissue1.29572394
51MP0003136_yellow_coat_color1.28194238
52MP0005275_abnormal_skin_tensile1.27115245
53MP0000537_abnormal_urethra_morphology1.26790915
54MP0010234_abnormal_vibrissa_follicle1.26549392
55MP0001299_abnormal_eye_distance/1.20796923
56MP0003634_abnormal_glial_cell1.19675698
57MP0005257_abnormal_intraocular_pressure1.18708502
58MP0003631_nervous_system_phenotype1.17865449
59MP0003385_abnormal_body_wall1.16906986
60MP0001984_abnormal_olfaction1.13913722
61MP0003787_abnormal_imprinting1.12181762
62MP0004742_abnormal_vestibular_system1.11821634
63MP0003283_abnormal_digestive_organ1.11145167
64MP0003690_abnormal_glial_cell1.11016259
65MP0003879_abnormal_hair_cell1.10607751
66MP0001177_atelectasis1.10122101
67MP0004142_abnormal_muscle_tone1.09466603
68MP0001905_abnormal_dopamine_level1.07354223
69MP0003942_abnormal_urinary_system1.07323786
70MP0003122_maternal_imprinting1.06753002
71MP0000569_abnormal_digit_pigmentation1.06491632
72MP0000762_abnormal_tongue_morphology1.05864852
73MP0003861_abnormal_nervous_system1.05049754
74MP0002837_dystrophic_cardiac_calcinosis1.04763713
75MP0002152_abnormal_brain_morphology1.03755743
76MP0005646_abnormal_pituitary_gland1.00567797
77MP0003123_paternal_imprinting1.00190324
78MP0001529_abnormal_vocalization0.97793147
79MP0003566_abnormal_cell_adhesion0.97071426
80MP0010368_abnormal_lymphatic_system0.95901037
81MP0005248_abnormal_Harderian_gland0.95387190
82MP0002229_neurodegeneration0.94334064
83MP0003632_abnormal_nervous_system0.93186921
84MP0003121_genomic_imprinting0.92810630
85MP0004484_altered_response_of0.91722854
86MP0000462_abnormal_digestive_system0.91229624
87MP0004085_abnormal_heartbeat0.90885255
88MP0004215_abnormal_myocardial_fiber0.90574403
89MP0004233_abnormal_muscle_weight0.89640487
90MP0002896_abnormal_bone_mineralization0.89395505
91MP0003045_fibrosis0.89335047
92MP0002877_abnormal_melanocyte_morpholog0.88959823
93MP0002697_abnormal_eye_size0.87691777
94MP0003091_abnormal_cell_migration0.87398940
95MP0003115_abnormal_respiratory_system0.86766882
96MP0001502_abnormal_circadian_rhythm0.85581755
97MP0010030_abnormal_orbit_morphology0.85394581
98MP0003890_abnormal_embryonic-extraembry0.84667101
99MP0001879_abnormal_lymphatic_vessel0.84480944
100MP0002090_abnormal_vision0.84377538
101MP0000604_amyloidosis0.82705800
102MP0005645_abnormal_hypothalamus_physiol0.82542795
103MP0005551_abnormal_eye_electrophysiolog0.82328102
104MP0000747_muscle_weakness0.82309171
105MP0002089_abnormal_postnatal_growth/wei0.82221996
106MP0002108_abnormal_muscle_morphology0.81922133
107MP0000428_abnormal_craniofacial_morphol0.81617838
108MP0002081_perinatal_lethality0.81363219
109MP0003755_abnormal_palate_morphology0.79984147
110MP0000534_abnormal_ureter_morphology0.77231134
111MP0003937_abnormal_limbs/digits/tail_de0.77147367
112MP0002116_abnormal_craniofacial_bone0.76421725
113MP0002069_abnormal_eating/drinking_beha0.75933193
114MP0002233_abnormal_nose_morphology0.75597218
115MP0009384_cardiac_valve_regurgitation0.75559883
116MP0003137_abnormal_impulse_conducting0.75033730
117MP0003935_abnormal_craniofacial_develop0.74853351
118MP0004036_abnormal_muscle_relaxation0.74598088
119MP0002752_abnormal_somatic_nervous0.74587195
120MP0003279_aneurysm0.73827672
121MP0005167_abnormal_blood-brain_barrier0.73459714
122MP0008874_decreased_physiological_sensi0.71578490
123MP0008961_abnormal_basal_metabolism0.71126991
124MP0001485_abnormal_pinna_reflex0.69390972
125MP0005409_darkened_coat_color0.68754810
126MP0005171_absent_coat_pigmentation0.68386099
127MP0008438_abnormal_cutaneous_collagen0.67842432
128MP0001963_abnormal_hearing_physiology0.67722862
129MP0010386_abnormal_urinary_bladder0.66998796
130MP0001943_abnormal_respiration0.64929299
131MP0005620_abnormal_muscle_contractility0.64366361
132MP0004130_abnormal_muscle_cell0.64363706
133MP0003075_altered_response_to0.62164360
134MP0002234_abnormal_pharynx_morphology0.61127402
135MP0000003_abnormal_adipose_tissue0.60980132
136MP0001958_emphysema0.59068135
137MP0005187_abnormal_penis_morphology0.58615216
138MP0004084_abnormal_cardiac_muscle0.58093175
139MP0008872_abnormal_physiological_respon0.57999803

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.90008118
2Focal motor seizures (HP:0011153)5.35266990
3Focal seizures (HP:0007359)4.88833608
4Action tremor (HP:0002345)4.37595486
5Visual hallucinations (HP:0002367)3.80729883
6Supranuclear gaze palsy (HP:0000605)3.66972343
7Atonic seizures (HP:0010819)3.52363645
8Progressive cerebellar ataxia (HP:0002073)3.49492325
9Ankle clonus (HP:0011448)3.42968652
10Insidious onset (HP:0003587)3.32399755
11Termporal pattern (HP:0011008)3.32399755
12Epileptic encephalopathy (HP:0200134)3.27212345
13Protrusio acetabuli (HP:0003179)3.24680831
14Absence seizures (HP:0002121)3.03122403
15Arterial tortuosity (HP:0005116)3.01550945
16Vascular tortuosity (HP:0004948)2.96381238
17Neurofibrillary tangles (HP:0002185)2.89281942
18Febrile seizures (HP:0002373)2.88843682
19Shallow orbits (HP:0000586)2.85847247
20Dysmetria (HP:0001310)2.83316165
21Dysdiadochokinesis (HP:0002075)2.78662590
22Generalized tonic-clonic seizures (HP:0002069)2.77752672
23Cerebral inclusion bodies (HP:0100314)2.77348122
24Dialeptic seizures (HP:0011146)2.76179660
25Neonatal short-limb short stature (HP:0008921)2.74182228
26Vertebral arch anomaly (HP:0008438)2.71203021
27Urinary urgency (HP:0000012)2.70306285
28Truncal ataxia (HP:0002078)2.70150979
29Intention tremor (HP:0002080)2.69774438
30Broad-based gait (HP:0002136)2.69094303
31Impaired vibration sensation in the lower limbs (HP:0002166)2.66984349
32Depression (HP:0000716)2.63476698
33Gaze-evoked nystagmus (HP:0000640)2.62111408
34Abnormality of the corticospinal tract (HP:0002492)2.61550378
35Urinary bladder sphincter dysfunction (HP:0002839)2.60803591
36Scanning speech (HP:0002168)2.55167000
37Spastic gait (HP:0002064)2.53947229
38Mutism (HP:0002300)2.53061216
39Megalencephaly (HP:0001355)2.49640228
40Poor eye contact (HP:0000817)2.48289979
41Turricephaly (HP:0000262)2.47323642
42Premature rupture of membranes (HP:0001788)2.45437616
43Pheochromocytoma (HP:0002666)2.41524070
44Obstructive sleep apnea (HP:0002870)2.36134318
45Papilledema (HP:0001085)2.36041417
46Ventricular fibrillation (HP:0001663)2.34954614
47Anxiety (HP:0000739)2.33750123
48Lower limb amyotrophy (HP:0007210)2.33628233
49Onion bulb formation (HP:0003383)2.33589567
50Impaired social interactions (HP:0000735)2.32792509
51Abnormal social behavior (HP:0012433)2.32792509
52Postural instability (HP:0002172)2.32185184
53Torticollis (HP:0000473)2.28977670
54Abnormal eating behavior (HP:0100738)2.28469365
55Lower limb muscle weakness (HP:0007340)2.26718138
56Bladder diverticulum (HP:0000015)2.22164898
57Abnormality of the lower motor neuron (HP:0002366)2.20789889
58Atrophic scars (HP:0001075)2.19308019
59Bundle branch block (HP:0011710)2.19071429
60Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.18963240
61Degeneration of the lateral corticospinal tracts (HP:0002314)2.18963240
62Aplasia involving bones of the extremities (HP:0009825)2.18316615
63Aplasia involving bones of the upper limbs (HP:0009823)2.18316615
64Aplasia of the phalanges of the hand (HP:0009802)2.18316615
65Amblyopia (HP:0000646)2.18036053
66Hemiparesis (HP:0001269)2.17508380
67Genetic anticipation (HP:0003743)2.16284297
68Limb dystonia (HP:0002451)2.12476900
69Hemiplegia (HP:0002301)2.07942141
70Coronal craniosynostosis (HP:0004440)2.07106044
71Insomnia (HP:0100785)2.06666642
72Hammertoe (HP:0001765)2.05570988
73Alacrima (HP:0000522)2.04845360
74Overgrowth (HP:0001548)2.04782441
75Aortic dissection (HP:0002647)2.04579301
76Cerebral aneurysm (HP:0004944)2.03985852
77Ulnar claw (HP:0001178)2.00491632
78Wide anterior fontanel (HP:0000260)2.00407599
79Dysmetric saccades (HP:0000641)1.99245343
80Buphthalmos (HP:0000557)1.99148727
81Rapidly progressive (HP:0003678)1.98271355
82Drooling (HP:0002307)1.97344156
83Excessive salivation (HP:0003781)1.97344156
84Prolonged QT interval (HP:0001657)1.96636656
85Progressive inability to walk (HP:0002505)1.95924965
86Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.95641066
87Peripheral hypomyelination (HP:0007182)1.95324758
88Fetal akinesia sequence (HP:0001989)1.94660669
89Abnormality of dentin (HP:0010299)1.94498093
90Stereotypic behavior (HP:0000733)1.94106080
91Hyperventilation (HP:0002883)1.92792722
92Hyperacusis (HP:0010780)1.92722015
93Neuronal loss in central nervous system (HP:0002529)1.92430465
94Focal dystonia (HP:0004373)1.91100271
95Neuroendocrine neoplasm (HP:0100634)1.91018342
96Broad metatarsal (HP:0001783)1.90692216
97Hypoventilation (HP:0002791)1.88357974
98Postural tremor (HP:0002174)1.88228946
99Pointed chin (HP:0000307)1.87762718
100Sleep apnea (HP:0010535)1.85690288
101Abnormality of binocular vision (HP:0011514)1.85556404
102Diplopia (HP:0000651)1.85556404
103Difficulty running (HP:0009046)1.85524792
104Bowel diverticulosis (HP:0005222)1.84905297
105Increased variability in muscle fiber diameter (HP:0003557)1.83911314
106Resting tremor (HP:0002322)1.82181425
107Aortic aneurysm (HP:0004942)1.81704114
108Mild short stature (HP:0003502)1.81418493
109Thickened helices (HP:0000391)1.81064561
110Impaired smooth pursuit (HP:0007772)1.80405348
111Bronchomalacia (HP:0002780)1.80356763
112Wormian bones (HP:0002645)1.79180628
113Mitral valve prolapse (HP:0001634)1.77350227
114Myotonia (HP:0002486)1.77199918
115Heterotopia (HP:0002282)1.77165998
116Clonus (HP:0002169)1.76817160
117Mitral regurgitation (HP:0001653)1.75954068
118Foot dorsiflexor weakness (HP:0009027)1.75477283
119Neoplasm of the peripheral nervous system (HP:0100007)1.75098557
120Craniofacial dystonia (HP:0012179)1.74741166
121Bradykinesia (HP:0002067)1.74409609
122Renal duplication (HP:0000075)1.74403670
123Agitation (HP:0000713)1.73036911
124Overriding aorta (HP:0002623)1.72751961
125Aqueductal stenosis (HP:0002410)1.72071823
126Ankyloglossia (HP:0010296)1.71954599
127Annular pancreas (HP:0001734)1.71648290
128Hyporeflexia of lower limbs (HP:0002600)1.71525145
129Apathy (HP:0000741)1.71313509
130Akinesia (HP:0002304)1.70901950
131Gait ataxia (HP:0002066)1.70683207
132Hyperextensible skin (HP:0000974)1.70446194
133Arnold-Chiari malformation (HP:0002308)1.70161723
134Neoplasm of the heart (HP:0100544)1.69247212
135Tracheomalacia (HP:0002779)1.63420549
136Cutaneous finger syndactyly (HP:0010554)1.62847988
137Soft skin (HP:0000977)1.60191782
138Renovascular hypertension (HP:0100817)1.58792028
139Cutaneous syndactyly (HP:0012725)1.58004279
140Decreased lacrimation (HP:0000633)1.57816254
141Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.55327945
142Ulnar bowing (HP:0003031)1.54768922
143Abnormality of the ischium (HP:0003174)1.50233962
144Pulmonic stenosis (HP:0001642)1.50048250
145Hypoplasia of the iris (HP:0007676)1.50027016
146Morphological abnormality of the middle ear (HP:0008609)1.49331275
147Papillary thyroid carcinoma (HP:0002895)1.48358508
148Cubitus valgus (HP:0002967)1.48132754
149Split foot (HP:0001839)1.48076625
150Blue irides (HP:0000635)1.47511043
151Elfin facies (HP:0004428)1.45317732
152Open mouth (HP:0000194)1.44707813
153Spinal rigidity (HP:0003306)1.44644735

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.55778299
2EPHA43.50255371
3MAP3K93.33214439
4MARK12.70028783
5MINK12.50865350
6MAP3K42.49458517
7PAK62.38969082
8NTRK12.23060434
9KSR22.20913109
10PRKD31.89329441
11DAPK21.84835662
12CAMKK11.69636015
13LATS11.61607139
14NTRK21.60426380
15MAP2K71.60215995
16MAP2K41.55553224
17KSR11.54885411
18EPHB21.52021001
19LMTK21.49510799
20CDK51.47774875
21RIPK41.44310821
22WNK11.40740333
23STK391.40529119
24PHKG21.39370638
25PHKG11.39370638
26STK381.38537399
27ICK1.36877645
28TYRO31.36513798
29MET1.30981806
30MAP3K21.30564635
31UHMK11.29531785
32OXSR11.25643537
33DDR21.24965728
34CDK191.23468018
35PTK21.19682920
36PAK31.19635137
37DMPK1.18708477
38PNCK1.18603109
39GRK51.15793916
40PLK21.13286801
41SGK21.11890512
42AKT31.11728424
43RET1.11134200
44EPHA31.10094860
45FGFR21.09151859
46LATS21.08406473
47MAP3K121.05829187
48PRKCH1.04231101
49PDGFRA1.03744898
50RIPK11.03418680
51CDK141.02008064
52CDK151.01972479
53CDK121.01762180
54CDK181.00718558
55CAMKK20.99564641
56SIK20.98567935
57CASK0.97658590
58MAPK130.97182716
59SGK2230.96828252
60SGK4940.96828252
61FER0.95305667
62CAMK1G0.95287266
63LIMK10.94593763
64MAPKAPK50.91212233
65FGFR40.90011753
66STK110.88993082
67CAMK2A0.88908312
68ARAF0.88630157
69PRKCG0.87696984
70CDK11A0.87469402
71CAMK2B0.86591493
72BRD40.86451305
73EEF2K0.85500643
74PIK3CA0.84970242
75TAOK10.84570996
76ROCK20.82410547
77PRPF4B0.82218786
78PTK2B0.81375589
79FES0.80395634
80PDPK10.80320939
81FGFR30.80163926
82MARK20.77895832
83CSNK1G20.77727863
84CAMK2D0.76691757
85PAK20.75828707
86MAP3K60.75237912
87MAP3K70.75191723
88RAF10.74600883
89ALK0.74459082
90MTOR0.72916554
91PDK10.71861535
92FGFR10.71831918
93WNK40.69987164
94MAP3K130.68952985
95NEK60.68567164
96CDC42BPA0.68382045
97MST1R0.68164457
98MAP2K10.67710851
99ERBB20.66622481
100DYRK1B0.66524915
101PKN20.66043871
102CAMK10.65696136
103PKN10.63145583
104ERBB40.62641646
105MAPK150.61878864
106TNIK0.61454259
107STK38L0.60486715
108SGK10.60266246
109PINK10.59674569
110SIK10.59402837
111MOS0.58330197
112CAMK2G0.57695863
113FGR0.57607559
114DAPK10.57377613
115ROCK10.57309936
116FYN0.57199165
117PRKCE0.56344493
118SGK30.56260510
119ERBB30.56170777
120BCR0.55745920
121RPS6KA20.52126043
122TRIB30.51796691
123CSNK1E0.51039796
124CAMK1D0.50355288
125PRKD10.50271109
126PDGFRB0.50093612
127MAPK100.48556389
128DYRK1A0.46606503
129TTN0.46566800
130RPS6KA30.46532971

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.83748359
2Synaptic vesicle cycle_Homo sapiens_hsa047212.68865353
3Olfactory transduction_Homo sapiens_hsa047402.29575147
4Circadian entrainment_Homo sapiens_hsa047132.29168862
5Long-term potentiation_Homo sapiens_hsa047202.26416270
6GABAergic synapse_Homo sapiens_hsa047272.26285499
7Glutamatergic synapse_Homo sapiens_hsa047242.19276607
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.18502601
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.17334593
10Morphine addiction_Homo sapiens_hsa050322.04988412
11Salivary secretion_Homo sapiens_hsa049701.99948653
12Amphetamine addiction_Homo sapiens_hsa050311.98078799
13Dopaminergic synapse_Homo sapiens_hsa047281.93541001
14Gastric acid secretion_Homo sapiens_hsa049711.87591528
15Cholinergic synapse_Homo sapiens_hsa047251.77883193
16Insulin secretion_Homo sapiens_hsa049111.68429084
17Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.68195197
18Renin secretion_Homo sapiens_hsa049241.66489312
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.61066503
20Oxytocin signaling pathway_Homo sapiens_hsa049211.58730222
21Long-term depression_Homo sapiens_hsa047301.57135809
22Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.50231990
23Cocaine addiction_Homo sapiens_hsa050301.48596217
24Gap junction_Homo sapiens_hsa045401.45249810
25* Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.45174224
26GnRH signaling pathway_Homo sapiens_hsa049121.44250276
27Taste transduction_Homo sapiens_hsa047421.40776153
28Serotonergic synapse_Homo sapiens_hsa047261.40379241
29Adherens junction_Homo sapiens_hsa045201.38567833
30Axon guidance_Homo sapiens_hsa043601.36888539
31Calcium signaling pathway_Homo sapiens_hsa040201.35248216
32Hippo signaling pathway_Homo sapiens_hsa043901.26051127
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24263860
34Glioma_Homo sapiens_hsa052141.23741337
35Nitrogen metabolism_Homo sapiens_hsa009101.22238467
36Estrogen signaling pathway_Homo sapiens_hsa049151.18930293
37cAMP signaling pathway_Homo sapiens_hsa040241.16734129
38Dilated cardiomyopathy_Homo sapiens_hsa054141.11268257
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.11100198
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10415150
41Cardiac muscle contraction_Homo sapiens_hsa042601.09700970
42Dorso-ventral axis formation_Homo sapiens_hsa043201.08196421
43Collecting duct acid secretion_Homo sapiens_hsa049661.06166936
44ErbB signaling pathway_Homo sapiens_hsa040121.05899850
45Melanogenesis_Homo sapiens_hsa049161.05505648
46cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05119678
47Type II diabetes mellitus_Homo sapiens_hsa049301.04274360
48Vascular smooth muscle contraction_Homo sapiens_hsa042701.03482534
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01144292
50Histidine metabolism_Homo sapiens_hsa003401.00595547
51Phospholipase D signaling pathway_Homo sapiens_hsa040721.00298322
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.98952379
53Protein digestion and absorption_Homo sapiens_hsa049740.96037527
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.95489382
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95049761
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91496799
57Hedgehog signaling pathway_Homo sapiens_hsa043400.91277811
58Basal cell carcinoma_Homo sapiens_hsa052170.90634057
59Pancreatic secretion_Homo sapiens_hsa049720.90457002
60Circadian rhythm_Homo sapiens_hsa047100.84553336
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82335547
62Notch signaling pathway_Homo sapiens_hsa043300.79139718
63MicroRNAs in cancer_Homo sapiens_hsa052060.78586119
64Thyroid hormone synthesis_Homo sapiens_hsa049180.78488380
65Vibrio cholerae infection_Homo sapiens_hsa051100.78445357
66Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.77314175
67Phototransduction_Homo sapiens_hsa047440.76386703
68Choline metabolism in cancer_Homo sapiens_hsa052310.75231447
69Vitamin B6 metabolism_Homo sapiens_hsa007500.75035517
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.75023740
71VEGF signaling pathway_Homo sapiens_hsa043700.74045481
72MAPK signaling pathway_Homo sapiens_hsa040100.73833555
73Tight junction_Homo sapiens_hsa045300.73618411
74Endocytosis_Homo sapiens_hsa041440.72669432
75Rap1 signaling pathway_Homo sapiens_hsa040150.72348086
76Renal cell carcinoma_Homo sapiens_hsa052110.72052965
77Oocyte meiosis_Homo sapiens_hsa041140.71212350
78Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71149303
79AMPK signaling pathway_Homo sapiens_hsa041520.70338578
80Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.69450436
81Colorectal cancer_Homo sapiens_hsa052100.69413564
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69338756
83Ras signaling pathway_Homo sapiens_hsa040140.67883345
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.67386282
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.65715982
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.65395973
87Chronic myeloid leukemia_Homo sapiens_hsa052200.64257496
88Endometrial cancer_Homo sapiens_hsa052130.60959943
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60293967
90Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59523955
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58872356
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57546935
93mTOR signaling pathway_Homo sapiens_hsa041500.57034450
94Wnt signaling pathway_Homo sapiens_hsa043100.56420283
95Glucagon signaling pathway_Homo sapiens_hsa049220.55881068
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55001465
97PI3K-Akt signaling pathway_Homo sapiens_hsa041510.54894090
98Pathways in cancer_Homo sapiens_hsa052000.54801615
99Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54469149
100Prolactin signaling pathway_Homo sapiens_hsa049170.54156807
101Focal adhesion_Homo sapiens_hsa045100.54011080
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52402758
103Arginine biosynthesis_Homo sapiens_hsa002200.52109720
104Inositol phosphate metabolism_Homo sapiens_hsa005620.50812887
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50777819
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48813969
107Insulin signaling pathway_Homo sapiens_hsa049100.46719293
108Non-small cell lung cancer_Homo sapiens_hsa052230.46688550
109Proteoglycans in cancer_Homo sapiens_hsa052050.46274032
110Alcoholism_Homo sapiens_hsa050340.46083166
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46046892
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45811872
113Bile secretion_Homo sapiens_hsa049760.44384136
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43962305
115Mineral absorption_Homo sapiens_hsa049780.43727203
116Prion diseases_Homo sapiens_hsa050200.42375824
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40697258
118Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.40506894
119Amoebiasis_Homo sapiens_hsa051460.40275723
120Platelet activation_Homo sapiens_hsa046110.39700051
121Ovarian steroidogenesis_Homo sapiens_hsa049130.39400481
122Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38314434
123ECM-receptor interaction_Homo sapiens_hsa045120.36224650

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