DYNLL1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.24446408
2translational termination (GO:0006415)6.91158590
3ribosomal small subunit assembly (GO:0000028)6.63954322
4chaperone-mediated protein transport (GO:0072321)6.13080224
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.02325563
6cotranslational protein targeting to membrane (GO:0006613)6.00584775
7protein targeting to ER (GO:0045047)5.93648338
8translational elongation (GO:0006414)5.83683238
9ribosomal small subunit biogenesis (GO:0042274)5.83554039
10establishment of protein localization to endoplasmic reticulum (GO:0072599)5.69847831
11energy coupled proton transport, down electrochemical gradient (GO:0015985)5.66117477
12ATP synthesis coupled proton transport (GO:0015986)5.66117477
13protein localization to endoplasmic reticulum (GO:0070972)5.56090267
14maturation of SSU-rRNA (GO:0030490)5.45878195
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.43818426
16cellular protein complex disassembly (GO:0043624)5.36942625
17mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.32913881
18viral life cycle (GO:0019058)5.15736440
19protein complex biogenesis (GO:0070271)5.10495109
20mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.09432032
21mitochondrial respiratory chain complex I assembly (GO:0032981)5.09432032
22NADH dehydrogenase complex assembly (GO:0010257)5.09432032
23mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.90293941
24mitochondrial respiratory chain complex assembly (GO:0033108)4.86177927
25translational initiation (GO:0006413)4.72627837
26protein complex disassembly (GO:0043241)4.56848851
27ribosomal large subunit biogenesis (GO:0042273)4.48298977
28respiratory electron transport chain (GO:0022904)4.48252740
29electron transport chain (GO:0022900)4.43018450
30protein neddylation (GO:0045116)4.32856488
31macromolecular complex disassembly (GO:0032984)4.24602321
32protein targeting to membrane (GO:0006612)4.16198680
33establishment of protein localization to mitochondrial membrane (GO:0090151)3.91725610
34translation (GO:0006412)3.88989939
35nuclear-transcribed mRNA catabolic process (GO:0000956)3.78057431
36negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.59668448
37inner mitochondrial membrane organization (GO:0007007)3.58937282
38mRNA catabolic process (GO:0006402)3.58004152
39CENP-A containing nucleosome assembly (GO:0034080)3.55482451
40cellular component biogenesis (GO:0044085)3.49176780
41epithelial cilium movement (GO:0003351)3.46066980
42chromatin remodeling at centromere (GO:0031055)3.43875362
43ATP biosynthetic process (GO:0006754)3.35560678
44rRNA modification (GO:0000154)3.29271647
45mitotic metaphase plate congression (GO:0007080)3.27688323
46kinetochore assembly (GO:0051382)3.26762023
47RNA catabolic process (GO:0006401)3.23940954
48hydrogen ion transmembrane transport (GO:1902600)3.21176589
49detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.21163963
50detection of temperature stimulus involved in sensory perception (GO:0050961)3.21163963
51tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.17942204
52RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.17942204
53ribonucleoprotein complex biogenesis (GO:0022613)3.15519609
54DNA double-strand break processing (GO:0000729)3.11784716
55DNA damage response, detection of DNA damage (GO:0042769)3.09919607
56sperm motility (GO:0030317)3.09852743
57negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.09816369
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.09769626
59histone exchange (GO:0043486)3.09133874
60purine nucleoside triphosphate biosynthetic process (GO:0009145)3.06930256
61negative regulation of DNA-templated transcription, elongation (GO:0032785)3.06837433
62kinetochore organization (GO:0051383)3.05424837
63positive regulation of gastrulation (GO:2000543)3.02665803
64lateral ventricle development (GO:0021670)3.00515574
65termination of RNA polymerase I transcription (GO:0006363)3.00452310
66metaphase plate congression (GO:0051310)2.89990417
67anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.86487143
68protein targeting (GO:0006605)2.85079133
69positive regulation of mitotic sister chromatid separation (GO:1901970)2.81253221
70positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.81253221
71positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.81253221
72regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.80558451
73negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.78744175
74negative regulation of ligase activity (GO:0051352)2.78744175
75pattern specification involved in kidney development (GO:0061004)2.78535765
76behavioral response to nicotine (GO:0035095)2.78307203
77proteasome assembly (GO:0043248)2.76831883
78replication fork processing (GO:0031297)2.76492440
79ribonucleoside triphosphate biosynthetic process (GO:0009201)2.75412513
80nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72426876
81positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.71650240
82cullin deneddylation (GO:0010388)2.71585257
83proton transport (GO:0015992)2.69876984
84cilium movement (GO:0003341)2.68336982
85establishment of protein localization to organelle (GO:0072594)2.68336073
86establishment of protein localization to membrane (GO:0090150)2.68176161
87head development (GO:0060322)2.67887005
88establishment of protein localization to mitochondrion (GO:0072655)2.67104841
89telencephalon development (GO:0021537)2.66037184
90protein targeting to mitochondrion (GO:0006626)2.65125531
91cellular response to interferon-beta (GO:0035458)2.63686863
92regulation of mitochondrial translation (GO:0070129)2.63376276
93rRNA methylation (GO:0031167)2.62277279
94anterograde synaptic vesicle transport (GO:0048490)2.62112838
95hydrogen transport (GO:0006818)2.61276944
96urogenital system development (GO:0001655)2.60651784
97negative regulation of translational initiation (GO:0045947)2.60609833
98positive regulation of prostaglandin secretion (GO:0032308)2.60423553
99iron coordination entity transport (GO:1901678)2.59019016
100transcription elongation from RNA polymerase I promoter (GO:0006362)2.58372598

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human5.02742850
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.68087850
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.80949131
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.70887032
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.63613998
6EZH2_22144423_ChIP-Seq_EOC_Human3.20908131
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.18945210
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.18744997
9FOXM1_23109430_ChIP-Seq_U2OS_Human3.04824284
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.99908161
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.87165115
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.85351460
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.79688500
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.65516383
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.63580765
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.57603968
17FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.51892255
18SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.26905371
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20765881
20VDR_23849224_ChIP-Seq_CD4+_Human2.11810484
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.99131938
22THAP11_20581084_ChIP-Seq_MESCs_Mouse1.97645028
23TTF2_22483619_ChIP-Seq_HELA_Human1.97040940
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.96736570
25XRN2_22483619_ChIP-Seq_HELA_Human1.95340748
26FOXP3_21729870_ChIP-Seq_TREG_Human1.88332784
27HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.87782418
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.85248495
29MYC_19079543_ChIP-ChIP_MESCs_Mouse1.83722215
30POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.83436387
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.81242273
32MYC_18940864_ChIP-ChIP_HL60_Human1.81010034
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.68489764
34CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.59340846
35MYC_19030024_ChIP-ChIP_MESCs_Mouse1.58436709
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.55042701
37IRF1_19129219_ChIP-ChIP_H3396_Human1.54719264
38MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53938541
39ELK1_19687146_ChIP-ChIP_HELA_Human1.52566364
40GATA1_26923725_Chip-Seq_HPCs_Mouse1.46884507
41MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.43969534
42EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.42855302
43DCP1A_22483619_ChIP-Seq_HELA_Human1.41635199
44RBPJ_22232070_ChIP-Seq_NCS_Mouse1.36767473
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36360940
46SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.33166215
47CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32399072
48SRF_21415370_ChIP-Seq_HL-1_Mouse1.31663489
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31216273
50KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.28717796
51CBX2_27304074_Chip-Seq_ESCs_Mouse1.26697585
52CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.26353839
53CIITA_25753668_ChIP-Seq_RAJI_Human1.25752529
54ELF1_17652178_ChIP-ChIP_JURKAT_Human1.24136435
55E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23531946
56CTCF_18555785_ChIP-Seq_MESCs_Mouse1.19821905
57SOX2_16153702_ChIP-ChIP_HESCs_Human1.16265278
58GABP_19822575_ChIP-Seq_HepG2_Human1.14750610
59ELF1_20517297_ChIP-Seq_JURKAT_Human1.14605495
60E2F1_17053090_ChIP-ChIP_MCF-7_Human1.09643113
61PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.08866632
62ZNF274_21170338_ChIP-Seq_K562_Hela1.08398237
63POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07837137
64MYC_19829295_ChIP-Seq_ESCs_Human1.06766749
65EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06015210
66ERA_21632823_ChIP-Seq_H3396_Human1.04352494
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02888349
68CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.02204175
69HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01528949
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01265095
71RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.00265982
72TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97378556
73TP63_19390658_ChIP-ChIP_HaCaT_Human0.95126668
74SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95095194
75RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94597730
76FUS_26573619_Chip-Seq_HEK293_Human0.92170126
77JARID2_20075857_ChIP-Seq_MESCs_Mouse0.91480035
78ESR1_15608294_ChIP-ChIP_MCF-7_Human0.91378178
79JARID2_20064375_ChIP-Seq_MESCs_Mouse0.89596118
80GATA3_21878914_ChIP-Seq_MCF-7_Human0.89554883
81NELFA_20434984_ChIP-Seq_ESCs_Mouse0.88462901
82EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.87267220
83AUTS2_25519132_ChIP-Seq_293T-REX_Human0.87029782
84CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.86687746
85HOXB4_20404135_ChIP-ChIP_EML_Mouse0.86648529
86FOXP1_21924763_ChIP-Seq_HESCs_Human0.86194441
87KDM5A_27292631_Chip-Seq_BREAST_Human0.86186642
88GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.86069797
89EZH2_27304074_Chip-Seq_ESCs_Mouse0.85520456
90MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.85253489
91NANOG_20526341_ChIP-Seq_ESCs_Human0.85080732
92* PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.84349470
93EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.83986601
94POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83847797
95EED_16625203_ChIP-ChIP_MESCs_Mouse0.82517598
96ELK1_22589737_ChIP-Seq_MCF10A_Human0.81929052
97YY1_22570637_ChIP-Seq_MALME-3M_Human0.81680557
98TDRD3_21172665_ChIP-Seq_MCF-7_Human0.81220327
99CTBP1_25329375_ChIP-Seq_LNCAP_Human0.80276010
100SRY_22984422_ChIP-ChIP_TESTIS_Rat0.79182774

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.13131866
2MP0000569_abnormal_digit_pigmentation3.65603890
3MP0002102_abnormal_ear_morphology2.96817775
4MP0005377_hearing/vestibular/ear_phenot2.65084115
5MP0003878_abnormal_ear_physiology2.65084115
6MP0003011_delayed_dark_adaptation2.63965928
7MP0003136_yellow_coat_color2.46509788
8MP0002653_abnormal_ependyma_morphology2.42284408
9MP0005645_abnormal_hypothalamus_physiol2.23796388
10MP0001293_anophthalmia2.23776148
11MP0001348_abnormal_lacrimal_gland2.23343266
12MP0003718_maternal_effect2.02249989
13MP0001919_abnormal_reproductive_system2.01880603
14MP0003122_maternal_imprinting1.96248748
15MP0002837_dystrophic_cardiac_calcinosis1.95784424
16MP0002736_abnormal_nociception_after1.92915503
17MP0008877_abnormal_DNA_methylation1.91538522
18MP0006292_abnormal_olfactory_placode1.83250903
19MP0001440_abnormal_grooming_behavior1.78082167
20MP0004142_abnormal_muscle_tone1.75407719
21MP0002638_abnormal_pupillary_reflex1.73776615
22MP0005410_abnormal_fertilization1.70211352
23MP0001873_stomach_inflammation1.68398591
24MP0002938_white_spotting1.66869578
25MP0001968_abnormal_touch/_nociception1.66387067
26MP0002095_abnormal_skin_pigmentation1.61791922
27MP0003121_genomic_imprinting1.57964842
28MP0003567_abnormal_fetal_cardiomyocyte1.55232352
29MP0008872_abnormal_physiological_respon1.54151854
30MP0004133_heterotaxia1.47942505
31MP0008875_abnormal_xenobiotic_pharmacok1.47823903
32MP0002735_abnormal_chemical_nociception1.44433371
33MP0005389_reproductive_system_phenotype1.44028984
34MP0003077_abnormal_cell_cycle1.43854308
35MP0000049_abnormal_middle_ear1.43022294
36MP0003186_abnormal_redox_activity1.43017206
37MP0002210_abnormal_sex_determination1.42657647
38MP0005551_abnormal_eye_electrophysiolog1.41306494
39MP0000566_synostosis1.40689208
40MP0001905_abnormal_dopamine_level1.37051122
41MP0006072_abnormal_retinal_apoptosis1.36330351
42MP0002272_abnormal_nervous_system1.35785980
43MP0003698_abnormal_male_reproductive1.34300687
44MP0006276_abnormal_autonomic_nervous1.32672033
45MP0008789_abnormal_olfactory_epithelium1.31276550
46MP0001485_abnormal_pinna_reflex1.30239624
47MP0001929_abnormal_gametogenesis1.24056079
48MP0002163_abnormal_gland_morphology1.22863533
49MP0003942_abnormal_urinary_system1.22002405
50MP0008058_abnormal_DNA_repair1.21526711
51MP0003119_abnormal_digestive_system1.21364753
52MP0006036_abnormal_mitochondrial_physio1.16679760
53MP0005423_abnormal_somatic_nervous1.16212398
54MP0001145_abnormal_male_reproductive1.14083573
55MP0005394_taste/olfaction_phenotype1.12968264
56MP0005499_abnormal_olfactory_system1.12968264
57MP0003646_muscle_fatigue1.11074214
58MP0000653_abnormal_sex_gland1.09626618
59MP0000026_abnormal_inner_ear1.07679510
60MP0005195_abnormal_posterior_eye1.07437394
61MP0004859_abnormal_synaptic_plasticity1.06828924
62MP0005075_abnormal_melanosome_morpholog1.06801356
63MP0000778_abnormal_nervous_system1.06282037
64MP0002928_abnormal_bile_duct1.03591542
65MP0001502_abnormal_circadian_rhythm1.03431795
66MP0002138_abnormal_hepatobiliary_system1.03015201
67MP0005253_abnormal_eye_physiology1.03011770
68MP0002234_abnormal_pharynx_morphology1.01620984
69MP0002277_abnormal_respiratory_mucosa0.99947732
70MP0004043_abnormal_pH_regulation0.98318616
71MP0001286_abnormal_eye_development0.97808403
72MP0002557_abnormal_social/conspecific_i0.96980973
73MP0004147_increased_porphyrin_level0.92870104
74MP0009046_muscle_twitch0.91835320
75MP0003890_abnormal_embryonic-extraembry0.91523031
76MP0004742_abnormal_vestibular_system0.90504238
77MP0005174_abnormal_tail_pigmentation0.89708301
78MP0006035_abnormal_mitochondrial_morpho0.88955490
79MP0002160_abnormal_reproductive_system0.88629071
80MP0001963_abnormal_hearing_physiology0.87534181
81MP0005084_abnormal_gallbladder_morpholo0.87531993
82MP0002752_abnormal_somatic_nervous0.86423676
83MP0002184_abnormal_innervation0.86292440
84MP0009053_abnormal_anal_canal0.86117447
85MP0003315_abnormal_perineum_morphology0.86044374
86MP0004145_abnormal_muscle_electrophysio0.85426110
87MP0005391_vision/eye_phenotype0.85380223
88MP0002733_abnormal_thermal_nociception0.84685314
89MP0003693_abnormal_embryo_hatching0.84658504
90MP0002132_abnormal_respiratory_system0.83076774
91MP0000750_abnormal_muscle_regeneration0.82938219
92MP0002161_abnormal_fertility/fecundity0.82202549
93MP0000631_abnormal_neuroendocrine_gland0.82099792
94MP0005670_abnormal_white_adipose0.79873337
95MP0003936_abnormal_reproductive_system0.78293073
96MP0010094_abnormal_chromosome_stability0.75938111
97MP0005636_abnormal_mineral_homeostasis0.71622925
98MP0000955_abnormal_spinal_cord0.68828852
99MP0001756_abnormal_urination0.68509162
100MP0009745_abnormal_behavioral_response0.68014180

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.62726267
2Abnormality of cells of the erythroid lineage (HP:0012130)4.50111834
3Mitochondrial inheritance (HP:0001427)4.42896484
4Abnormal mitochondria in muscle tissue (HP:0008316)4.37054475
5Acute encephalopathy (HP:0006846)4.31973155
6Increased hepatocellular lipid droplets (HP:0006565)4.27468776
7Lipid accumulation in hepatocytes (HP:0006561)4.15980760
8Renal Fanconi syndrome (HP:0001994)3.93089123
9Occipital encephalocele (HP:0002085)3.88028313
10True hermaphroditism (HP:0010459)3.87784532
11Abnormal number of erythroid precursors (HP:0012131)3.84935353
12Pancreatic fibrosis (HP:0100732)3.80362216
13Hepatocellular necrosis (HP:0001404)3.79704868
14Pancreatic cysts (HP:0001737)3.78686768
15Hepatic necrosis (HP:0002605)3.61048605
16Increased CSF lactate (HP:0002490)3.60626008
17Progressive macrocephaly (HP:0004481)3.52029184
18Macrocytic anemia (HP:0001972)3.49096111
19Reticulocytopenia (HP:0001896)3.47412377
20Increased intramyocellular lipid droplets (HP:0012240)3.36866997
21Abnormality of the pons (HP:0007361)3.31285980
22Hypoplasia of the pons (HP:0012110)3.25665341
23Type II lissencephaly (HP:0007260)3.19872031
24Abnormal biliary tract physiology (HP:0012439)3.10475572
25Bile duct proliferation (HP:0001408)3.10475572
26Cystic liver disease (HP:0006706)3.06035286
27Cerebral edema (HP:0002181)3.00443617
28Colon cancer (HP:0003003)2.98998446
29Chronic hepatic failure (HP:0100626)2.95859458
30Increased muscle lipid content (HP:0009058)2.93015679
31Supernumerary spleens (HP:0009799)2.92051929
32Exertional dyspnea (HP:0002875)2.86480660
33Abnormality of renal resorption (HP:0011038)2.81305914
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.72300978
35Cerebellar dysplasia (HP:0007033)2.65595838
36Abnormality of urine glucose concentration (HP:0011016)2.61878054
37Glycosuria (HP:0003076)2.61878054
38Male pseudohermaphroditism (HP:0000037)2.60049706
39Microvesicular hepatic steatosis (HP:0001414)2.59909952
40Abnormality of the labia minora (HP:0012880)2.57033232
41Oligodactyly (hands) (HP:0001180)2.55393334
42Anomalous pulmonary venous return (HP:0010772)2.47160515
43Exercise intolerance (HP:0003546)2.45699056
44Respiratory failure (HP:0002878)2.43438798
45Aplasia/Hypoplasia of the sacrum (HP:0008517)2.38264934
46Medial flaring of the eyebrow (HP:0010747)2.38065911
47Hyperglycinemia (HP:0002154)2.35939858
48Long foot (HP:0001833)2.35748231
49Optic nerve coloboma (HP:0000588)2.32482249
50Increased serum lactate (HP:0002151)2.28480414
51Hyperphosphaturia (HP:0003109)2.27705839
52Anencephaly (HP:0002323)2.25590397
53Cerebral hypomyelination (HP:0006808)2.25588427
54Hip dysplasia (HP:0001385)2.23949281
55Pendular nystagmus (HP:0012043)2.18427863
56Sclerocornea (HP:0000647)2.18215857
57Oligodactyly (HP:0012165)2.14572724
58Absent thumb (HP:0009777)2.13857675
59Generalized aminoaciduria (HP:0002909)2.13671448
60Abnormality of midbrain morphology (HP:0002418)2.12064153
61Molar tooth sign on MRI (HP:0002419)2.12064153
62Hypomagnesemia (HP:0002917)2.08979067
63Abnormality of the pulmonary veins (HP:0011718)2.08935245
64Congenital hepatic fibrosis (HP:0002612)2.07277363
65Respiratory difficulties (HP:0002880)2.04706949
66Muscle fiber atrophy (HP:0100295)2.04093862
67Optic disc pallor (HP:0000543)2.04078361
68Hyperglycinuria (HP:0003108)2.03754628
69Abnormal number of incisors (HP:0011064)2.01773245
70Rib fusion (HP:0000902)2.01254870
71Nephronophthisis (HP:0000090)2.00794526
72Gait imbalance (HP:0002141)2.00163310
73Lethargy (HP:0001254)2.00086040
74Lactic acidosis (HP:0003128)1.99689065
75Pallor (HP:0000980)1.99518236
76Type 2 muscle fiber atrophy (HP:0003554)1.97581329
77Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.96643115
78Decreased activity of mitochondrial respiratory chain (HP:0008972)1.96643115
79Abnormal ciliary motility (HP:0012262)1.94964657
80Abnormality of lateral ventricle (HP:0030047)1.94559308
81Blindness (HP:0000618)1.94239239
82Meckel diverticulum (HP:0002245)1.93366848
83Congenital primary aphakia (HP:0007707)1.92639308
84Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.92026059
85Nephrogenic diabetes insipidus (HP:0009806)1.91823509
86Hypoplasia of the radius (HP:0002984)1.87298169
87Anophthalmia (HP:0000528)1.86714776
88Abnormality of the ileum (HP:0001549)1.86204771
893-Methylglutaconic aciduria (HP:0003535)1.85864660
90Abnormality of the anterior horn cell (HP:0006802)1.83641060
91Degeneration of anterior horn cells (HP:0002398)1.83641060
92Myokymia (HP:0002411)1.82833747
93Volvulus (HP:0002580)1.81062636
94Aplasia/Hypoplasia of the tongue (HP:0010295)1.79697459
95Congenital, generalized hypertrichosis (HP:0004540)1.76795704
96Depressed nasal ridge (HP:0000457)1.74852976
97Abnormal hair whorl (HP:0010721)1.73999467
98Tachypnea (HP:0002789)1.73171425
99Abnormal urine phosphate concentration (HP:0012599)1.72866786
100Lissencephaly (HP:0001339)1.72775207

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.51058274
2STK163.73273921
3VRK13.71228283
4BUB13.15208845
5ZAK2.93798955
6BRSK12.71383435
7BCKDK2.53048977
8CDC72.40634893
9NME12.33627672
10SRPK12.12057240
11PBK2.07621192
12MKNK21.96901751
13MAP4K21.96309703
14DYRK21.92300862
15NME21.88639878
16CDK81.79232143
17BRSK21.77278337
18PASK1.57853419
19STK41.54200298
20WNK41.47187054
21TLK11.43760232
22AURKA1.40322455
23NEK11.32197342
24MAP3K91.30312842
25PLK11.24969140
26DAPK31.24911528
27TTK1.20922367
28BMPR1B1.20642231
29WNK11.18877052
30PLK41.18151640
31PIM21.18079878
32PAK41.17531365
33AURKB1.17418859
34MKNK11.15872391
35WEE11.15684647
36RPS6KA61.13366496
37PRKCG1.13053566
38PLK31.12026484
39NEK21.11468565
40RPS6KL11.10820563
41RPS6KC11.10820563
42TNK21.04091905
43INSRR1.00929998
44GRK10.99790995
45WNK30.99583698
46RPS6KA50.96376327
47PKN10.95884706
48NTRK20.92412509
49MST40.85628250
50MAP2K20.85180562
51CASK0.84020098
52ADRBK20.81336131
53UHMK10.80105012
54MELK0.76617344
55MAP3K40.75474595
56STK390.75297349
57TYRO30.74270988
58MARK30.70271487
59CSNK2A20.69986671
60EIF2AK10.66086068
61PIK3CG0.65568319
62STK110.65008490
63PAK60.64147354
64PRKCQ0.64131493
65MAP2K70.62203013
66STK240.62007545
67ABL20.61922024
68EPHA30.61086076
69PRKACA0.57270609
70IRAK40.57062489
71CAMK10.56239183
72DDR20.56111883
73PAK30.54768500
74PRKCH0.53181112
75TSSK60.52938785
76GRK70.52541386
77MAPK150.51243160
78IKBKB0.50213107
79TNIK0.49727138
80MINK10.49157246
81NLK0.48030098
82PAK10.45911069
83CSNK1E0.45079932
84CSNK2A10.44904654
85DYRK30.44535727
86BMX0.44365126
87MAP3K110.44052998
88ATR0.43734020
89PRKACG0.42827768
90LRRK20.41020785
91RPS6KA10.40607536
92CCNB10.39117835
93PHKG20.39106552
94PHKG10.39106552
95CAMK40.37538529
96PLK20.36629735
97PRKCD0.36045389
98SGK10.35185944
99MAP3K80.34661971
100MUSK0.34557650

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.19691529
2Oxidative phosphorylation_Homo sapiens_hsa001904.74222616
3Parkinsons disease_Homo sapiens_hsa050124.19079079
4Proteasome_Homo sapiens_hsa030503.39841847
5Huntingtons disease_Homo sapiens_hsa050162.91708340
6Alzheimers disease_Homo sapiens_hsa050102.85422844
7Protein export_Homo sapiens_hsa030602.84664990
8RNA polymerase_Homo sapiens_hsa030202.60839270
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.59241338
10Cardiac muscle contraction_Homo sapiens_hsa042602.39199000
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.92565732
12Systemic lupus erythematosus_Homo sapiens_hsa053221.85515485
13Fanconi anemia pathway_Homo sapiens_hsa034601.82530275
14Homologous recombination_Homo sapiens_hsa034401.72714598
15Sulfur relay system_Homo sapiens_hsa041221.71563196
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.65519110
17Spliceosome_Homo sapiens_hsa030401.62814667
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.57203875
19One carbon pool by folate_Homo sapiens_hsa006701.51261868
20Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.48690526
21Mismatch repair_Homo sapiens_hsa034301.47553153
22RNA transport_Homo sapiens_hsa030131.40420164
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.35556207
24Propanoate metabolism_Homo sapiens_hsa006401.29077994
25Nucleotide excision repair_Homo sapiens_hsa034201.28420784
26Butanoate metabolism_Homo sapiens_hsa006501.28331700
27Basal transcription factors_Homo sapiens_hsa030221.22824815
28Alcoholism_Homo sapiens_hsa050341.20903208
29RNA degradation_Homo sapiens_hsa030181.19599221
30Arginine and proline metabolism_Homo sapiens_hsa003301.15170942
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.11127711
32DNA replication_Homo sapiens_hsa030301.08767115
33Base excision repair_Homo sapiens_hsa034101.03917461
34Pyrimidine metabolism_Homo sapiens_hsa002401.03678680
35Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.97067888
36Intestinal immune network for IgA production_Homo sapiens_hsa046720.94623227
37Nitrogen metabolism_Homo sapiens_hsa009100.94190939
38Asthma_Homo sapiens_hsa053100.93858363
39Phototransduction_Homo sapiens_hsa047440.89746311
40Allograft rejection_Homo sapiens_hsa053300.86401478
41p53 signaling pathway_Homo sapiens_hsa041150.85241008
42Peroxisome_Homo sapiens_hsa041460.85240876
43Autoimmune thyroid disease_Homo sapiens_hsa053200.82613989
44Folate biosynthesis_Homo sapiens_hsa007900.82308282
45beta-Alanine metabolism_Homo sapiens_hsa004100.81727469
46Arginine biosynthesis_Homo sapiens_hsa002200.79686611
47Linoleic acid metabolism_Homo sapiens_hsa005910.79443118
48Nicotine addiction_Homo sapiens_hsa050330.76738673
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76183054
50Metabolic pathways_Homo sapiens_hsa011000.73466587
51Fatty acid degradation_Homo sapiens_hsa000710.73139655
52alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69749706
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69535878
54Cysteine and methionine metabolism_Homo sapiens_hsa002700.69159800
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68956363
56Basal cell carcinoma_Homo sapiens_hsa052170.68366116
57Caffeine metabolism_Homo sapiens_hsa002320.67755711
58Purine metabolism_Homo sapiens_hsa002300.67014607
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.64313671
60Vitamin digestion and absorption_Homo sapiens_hsa049770.64263821
61Tryptophan metabolism_Homo sapiens_hsa003800.61764303
62Cell cycle_Homo sapiens_hsa041100.58518534
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.56183832
64Olfactory transduction_Homo sapiens_hsa047400.54643132
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54319116
66Tyrosine metabolism_Homo sapiens_hsa003500.53630272
672-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52436660
68Hedgehog signaling pathway_Homo sapiens_hsa043400.50589528
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48318112
70Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.47743102
71Chemical carcinogenesis_Homo sapiens_hsa052040.47242629
72Biosynthesis of amino acids_Homo sapiens_hsa012300.46040094
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.44166271
74Primary immunodeficiency_Homo sapiens_hsa053400.44141848
75Mineral absorption_Homo sapiens_hsa049780.38490913
76Pyruvate metabolism_Homo sapiens_hsa006200.38227192
77Retinol metabolism_Homo sapiens_hsa008300.38010463
78Phenylalanine metabolism_Homo sapiens_hsa003600.37774280
79Collecting duct acid secretion_Homo sapiens_hsa049660.37497178
80Oocyte meiosis_Homo sapiens_hsa041140.37232396
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.36093832
82Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.33928031
83Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33727432
84Arachidonic acid metabolism_Homo sapiens_hsa005900.29067279
85Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.27807860
86Insulin secretion_Homo sapiens_hsa049110.27269512
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.27189758
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25480925
89Glycerolipid metabolism_Homo sapiens_hsa005610.24181557
90Salivary secretion_Homo sapiens_hsa049700.22515622
91Taste transduction_Homo sapiens_hsa047420.22481011
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.22156062
93Antigen processing and presentation_Homo sapiens_hsa046120.21197254
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.20719690
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.19558232
96Carbon metabolism_Homo sapiens_hsa012000.19519394
97Fat digestion and absorption_Homo sapiens_hsa049750.19311969
98Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.18289088
99Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.17938281
100Fatty acid elongation_Homo sapiens_hsa000620.15989041

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »