

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 7.24446408 |
| 2 | translational termination (GO:0006415) | 6.91158590 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 6.63954322 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 6.13080224 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.02325563 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 6.00584775 |
| 7 | protein targeting to ER (GO:0045047) | 5.93648338 |
| 8 | translational elongation (GO:0006414) | 5.83683238 |
| 9 | ribosomal small subunit biogenesis (GO:0042274) | 5.83554039 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.69847831 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.66117477 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 5.66117477 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 5.56090267 |
| 14 | maturation of SSU-rRNA (GO:0030490) | 5.45878195 |
| 15 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.43818426 |
| 16 | cellular protein complex disassembly (GO:0043624) | 5.36942625 |
| 17 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.32913881 |
| 18 | viral life cycle (GO:0019058) | 5.15736440 |
| 19 | protein complex biogenesis (GO:0070271) | 5.10495109 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.09432032 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.09432032 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 5.09432032 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.90293941 |
| 24 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.86177927 |
| 25 | translational initiation (GO:0006413) | 4.72627837 |
| 26 | protein complex disassembly (GO:0043241) | 4.56848851 |
| 27 | ribosomal large subunit biogenesis (GO:0042273) | 4.48298977 |
| 28 | respiratory electron transport chain (GO:0022904) | 4.48252740 |
| 29 | electron transport chain (GO:0022900) | 4.43018450 |
| 30 | protein neddylation (GO:0045116) | 4.32856488 |
| 31 | macromolecular complex disassembly (GO:0032984) | 4.24602321 |
| 32 | protein targeting to membrane (GO:0006612) | 4.16198680 |
| 33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.91725610 |
| 34 | translation (GO:0006412) | 3.88989939 |
| 35 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.78057431 |
| 36 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.59668448 |
| 37 | inner mitochondrial membrane organization (GO:0007007) | 3.58937282 |
| 38 | mRNA catabolic process (GO:0006402) | 3.58004152 |
| 39 | CENP-A containing nucleosome assembly (GO:0034080) | 3.55482451 |
| 40 | cellular component biogenesis (GO:0044085) | 3.49176780 |
| 41 | epithelial cilium movement (GO:0003351) | 3.46066980 |
| 42 | chromatin remodeling at centromere (GO:0031055) | 3.43875362 |
| 43 | ATP biosynthetic process (GO:0006754) | 3.35560678 |
| 44 | rRNA modification (GO:0000154) | 3.29271647 |
| 45 | mitotic metaphase plate congression (GO:0007080) | 3.27688323 |
| 46 | kinetochore assembly (GO:0051382) | 3.26762023 |
| 47 | RNA catabolic process (GO:0006401) | 3.23940954 |
| 48 | hydrogen ion transmembrane transport (GO:1902600) | 3.21176589 |
| 49 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.21163963 |
| 50 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.21163963 |
| 51 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.17942204 |
| 52 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.17942204 |
| 53 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.15519609 |
| 54 | DNA double-strand break processing (GO:0000729) | 3.11784716 |
| 55 | DNA damage response, detection of DNA damage (GO:0042769) | 3.09919607 |
| 56 | sperm motility (GO:0030317) | 3.09852743 |
| 57 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.09816369 |
| 58 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.09769626 |
| 59 | histone exchange (GO:0043486) | 3.09133874 |
| 60 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.06930256 |
| 61 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.06837433 |
| 62 | kinetochore organization (GO:0051383) | 3.05424837 |
| 63 | positive regulation of gastrulation (GO:2000543) | 3.02665803 |
| 64 | lateral ventricle development (GO:0021670) | 3.00515574 |
| 65 | termination of RNA polymerase I transcription (GO:0006363) | 3.00452310 |
| 66 | metaphase plate congression (GO:0051310) | 2.89990417 |
| 67 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.86487143 |
| 68 | protein targeting (GO:0006605) | 2.85079133 |
| 69 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.81253221 |
| 70 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.81253221 |
| 71 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.81253221 |
| 72 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.80558451 |
| 73 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.78744175 |
| 74 | negative regulation of ligase activity (GO:0051352) | 2.78744175 |
| 75 | pattern specification involved in kidney development (GO:0061004) | 2.78535765 |
| 76 | behavioral response to nicotine (GO:0035095) | 2.78307203 |
| 77 | proteasome assembly (GO:0043248) | 2.76831883 |
| 78 | replication fork processing (GO:0031297) | 2.76492440 |
| 79 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.75412513 |
| 80 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.72426876 |
| 81 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.71650240 |
| 82 | cullin deneddylation (GO:0010388) | 2.71585257 |
| 83 | proton transport (GO:0015992) | 2.69876984 |
| 84 | cilium movement (GO:0003341) | 2.68336982 |
| 85 | establishment of protein localization to organelle (GO:0072594) | 2.68336073 |
| 86 | establishment of protein localization to membrane (GO:0090150) | 2.68176161 |
| 87 | head development (GO:0060322) | 2.67887005 |
| 88 | establishment of protein localization to mitochondrion (GO:0072655) | 2.67104841 |
| 89 | telencephalon development (GO:0021537) | 2.66037184 |
| 90 | protein targeting to mitochondrion (GO:0006626) | 2.65125531 |
| 91 | cellular response to interferon-beta (GO:0035458) | 2.63686863 |
| 92 | regulation of mitochondrial translation (GO:0070129) | 2.63376276 |
| 93 | rRNA methylation (GO:0031167) | 2.62277279 |
| 94 | anterograde synaptic vesicle transport (GO:0048490) | 2.62112838 |
| 95 | hydrogen transport (GO:0006818) | 2.61276944 |
| 96 | urogenital system development (GO:0001655) | 2.60651784 |
| 97 | negative regulation of translational initiation (GO:0045947) | 2.60609833 |
| 98 | positive regulation of prostaglandin secretion (GO:0032308) | 2.60423553 |
| 99 | iron coordination entity transport (GO:1901678) | 2.59019016 |
| 100 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.58372598 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.02742850 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.68087850 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.80949131 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.70887032 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.63613998 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.20908131 |
| 7 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.18945210 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.18744997 |
| 9 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.04824284 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.99908161 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.87165115 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.85351460 |
| 13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.79688500 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.65516383 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.63580765 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.57603968 |
| 17 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.51892255 |
| 18 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.26905371 |
| 19 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.20765881 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.11810484 |
| 21 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.99131938 |
| 22 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.97645028 |
| 23 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.97040940 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.96736570 |
| 25 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.95340748 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.88332784 |
| 27 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.87782418 |
| 28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.85248495 |
| 29 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.83722215 |
| 30 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.83436387 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.81242273 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81010034 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68489764 |
| 34 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.59340846 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.58436709 |
| 36 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.55042701 |
| 37 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.54719264 |
| 38 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.53938541 |
| 39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.52566364 |
| 40 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.46884507 |
| 41 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.43969534 |
| 42 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.42855302 |
| 43 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.41635199 |
| 44 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.36767473 |
| 45 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.36360940 |
| 46 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.33166215 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.32399072 |
| 48 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.31663489 |
| 49 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.31216273 |
| 50 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.28717796 |
| 51 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.26697585 |
| 52 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.26353839 |
| 53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.25752529 |
| 54 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.24136435 |
| 55 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.23531946 |
| 56 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.19821905 |
| 57 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.16265278 |
| 58 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14750610 |
| 59 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.14605495 |
| 60 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 1.09643113 |
| 61 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.08866632 |
| 62 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.08398237 |
| 63 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07837137 |
| 64 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.06766749 |
| 65 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.06015210 |
| 66 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04352494 |
| 67 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.02888349 |
| 68 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.02204175 |
| 69 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.01528949 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01265095 |
| 71 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00265982 |
| 72 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97378556 |
| 73 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.95126668 |
| 74 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.95095194 |
| 75 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.94597730 |
| 76 | FUS_26573619_Chip-Seq_HEK293_Human | 0.92170126 |
| 77 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.91480035 |
| 78 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.91378178 |
| 79 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.89596118 |
| 80 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.89554883 |
| 81 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.88462901 |
| 82 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.87267220 |
| 83 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87029782 |
| 84 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.86687746 |
| 85 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.86648529 |
| 86 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.86194441 |
| 87 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.86186642 |
| 88 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86069797 |
| 89 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.85520456 |
| 90 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.85253489 |
| 91 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.85080732 |
| 92 | * PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.84349470 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.83986601 |
| 94 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.83847797 |
| 95 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.82517598 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.81929052 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.81680557 |
| 98 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.81220327 |
| 99 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.80276010 |
| 100 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.79182774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.13131866 |
| 2 | MP0000569_abnormal_digit_pigmentation | 3.65603890 |
| 3 | MP0002102_abnormal_ear_morphology | 2.96817775 |
| 4 | MP0005377_hearing/vestibular/ear_phenot | 2.65084115 |
| 5 | MP0003878_abnormal_ear_physiology | 2.65084115 |
| 6 | MP0003011_delayed_dark_adaptation | 2.63965928 |
| 7 | MP0003136_yellow_coat_color | 2.46509788 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.42284408 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 2.23796388 |
| 10 | MP0001293_anophthalmia | 2.23776148 |
| 11 | MP0001348_abnormal_lacrimal_gland | 2.23343266 |
| 12 | MP0003718_maternal_effect | 2.02249989 |
| 13 | MP0001919_abnormal_reproductive_system | 2.01880603 |
| 14 | MP0003122_maternal_imprinting | 1.96248748 |
| 15 | MP0002837_dystrophic_cardiac_calcinosis | 1.95784424 |
| 16 | MP0002736_abnormal_nociception_after | 1.92915503 |
| 17 | MP0008877_abnormal_DNA_methylation | 1.91538522 |
| 18 | MP0006292_abnormal_olfactory_placode | 1.83250903 |
| 19 | MP0001440_abnormal_grooming_behavior | 1.78082167 |
| 20 | MP0004142_abnormal_muscle_tone | 1.75407719 |
| 21 | MP0002638_abnormal_pupillary_reflex | 1.73776615 |
| 22 | MP0005410_abnormal_fertilization | 1.70211352 |
| 23 | MP0001873_stomach_inflammation | 1.68398591 |
| 24 | MP0002938_white_spotting | 1.66869578 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.66387067 |
| 26 | MP0002095_abnormal_skin_pigmentation | 1.61791922 |
| 27 | MP0003121_genomic_imprinting | 1.57964842 |
| 28 | MP0003567_abnormal_fetal_cardiomyocyte | 1.55232352 |
| 29 | MP0008872_abnormal_physiological_respon | 1.54151854 |
| 30 | MP0004133_heterotaxia | 1.47942505 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.47823903 |
| 32 | MP0002735_abnormal_chemical_nociception | 1.44433371 |
| 33 | MP0005389_reproductive_system_phenotype | 1.44028984 |
| 34 | MP0003077_abnormal_cell_cycle | 1.43854308 |
| 35 | MP0000049_abnormal_middle_ear | 1.43022294 |
| 36 | MP0003186_abnormal_redox_activity | 1.43017206 |
| 37 | MP0002210_abnormal_sex_determination | 1.42657647 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.41306494 |
| 39 | MP0000566_synostosis | 1.40689208 |
| 40 | MP0001905_abnormal_dopamine_level | 1.37051122 |
| 41 | MP0006072_abnormal_retinal_apoptosis | 1.36330351 |
| 42 | MP0002272_abnormal_nervous_system | 1.35785980 |
| 43 | MP0003698_abnormal_male_reproductive | 1.34300687 |
| 44 | MP0006276_abnormal_autonomic_nervous | 1.32672033 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 1.31276550 |
| 46 | MP0001485_abnormal_pinna_reflex | 1.30239624 |
| 47 | MP0001929_abnormal_gametogenesis | 1.24056079 |
| 48 | MP0002163_abnormal_gland_morphology | 1.22863533 |
| 49 | MP0003942_abnormal_urinary_system | 1.22002405 |
| 50 | MP0008058_abnormal_DNA_repair | 1.21526711 |
| 51 | MP0003119_abnormal_digestive_system | 1.21364753 |
| 52 | MP0006036_abnormal_mitochondrial_physio | 1.16679760 |
| 53 | MP0005423_abnormal_somatic_nervous | 1.16212398 |
| 54 | MP0001145_abnormal_male_reproductive | 1.14083573 |
| 55 | MP0005394_taste/olfaction_phenotype | 1.12968264 |
| 56 | MP0005499_abnormal_olfactory_system | 1.12968264 |
| 57 | MP0003646_muscle_fatigue | 1.11074214 |
| 58 | MP0000653_abnormal_sex_gland | 1.09626618 |
| 59 | MP0000026_abnormal_inner_ear | 1.07679510 |
| 60 | MP0005195_abnormal_posterior_eye | 1.07437394 |
| 61 | MP0004859_abnormal_synaptic_plasticity | 1.06828924 |
| 62 | MP0005075_abnormal_melanosome_morpholog | 1.06801356 |
| 63 | MP0000778_abnormal_nervous_system | 1.06282037 |
| 64 | MP0002928_abnormal_bile_duct | 1.03591542 |
| 65 | MP0001502_abnormal_circadian_rhythm | 1.03431795 |
| 66 | MP0002138_abnormal_hepatobiliary_system | 1.03015201 |
| 67 | MP0005253_abnormal_eye_physiology | 1.03011770 |
| 68 | MP0002234_abnormal_pharynx_morphology | 1.01620984 |
| 69 | MP0002277_abnormal_respiratory_mucosa | 0.99947732 |
| 70 | MP0004043_abnormal_pH_regulation | 0.98318616 |
| 71 | MP0001286_abnormal_eye_development | 0.97808403 |
| 72 | MP0002557_abnormal_social/conspecific_i | 0.96980973 |
| 73 | MP0004147_increased_porphyrin_level | 0.92870104 |
| 74 | MP0009046_muscle_twitch | 0.91835320 |
| 75 | MP0003890_abnormal_embryonic-extraembry | 0.91523031 |
| 76 | MP0004742_abnormal_vestibular_system | 0.90504238 |
| 77 | MP0005174_abnormal_tail_pigmentation | 0.89708301 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.88955490 |
| 79 | MP0002160_abnormal_reproductive_system | 0.88629071 |
| 80 | MP0001963_abnormal_hearing_physiology | 0.87534181 |
| 81 | MP0005084_abnormal_gallbladder_morpholo | 0.87531993 |
| 82 | MP0002752_abnormal_somatic_nervous | 0.86423676 |
| 83 | MP0002184_abnormal_innervation | 0.86292440 |
| 84 | MP0009053_abnormal_anal_canal | 0.86117447 |
| 85 | MP0003315_abnormal_perineum_morphology | 0.86044374 |
| 86 | MP0004145_abnormal_muscle_electrophysio | 0.85426110 |
| 87 | MP0005391_vision/eye_phenotype | 0.85380223 |
| 88 | MP0002733_abnormal_thermal_nociception | 0.84685314 |
| 89 | MP0003693_abnormal_embryo_hatching | 0.84658504 |
| 90 | MP0002132_abnormal_respiratory_system | 0.83076774 |
| 91 | MP0000750_abnormal_muscle_regeneration | 0.82938219 |
| 92 | MP0002161_abnormal_fertility/fecundity | 0.82202549 |
| 93 | MP0000631_abnormal_neuroendocrine_gland | 0.82099792 |
| 94 | MP0005670_abnormal_white_adipose | 0.79873337 |
| 95 | MP0003936_abnormal_reproductive_system | 0.78293073 |
| 96 | MP0010094_abnormal_chromosome_stability | 0.75938111 |
| 97 | MP0005636_abnormal_mineral_homeostasis | 0.71622925 |
| 98 | MP0000955_abnormal_spinal_cord | 0.68828852 |
| 99 | MP0001756_abnormal_urination | 0.68509162 |
| 100 | MP0009745_abnormal_behavioral_response | 0.68014180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.62726267 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.50111834 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.42896484 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.37054475 |
| 5 | Acute encephalopathy (HP:0006846) | 4.31973155 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.27468776 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 4.15980760 |
| 8 | Renal Fanconi syndrome (HP:0001994) | 3.93089123 |
| 9 | Occipital encephalocele (HP:0002085) | 3.88028313 |
| 10 | True hermaphroditism (HP:0010459) | 3.87784532 |
| 11 | Abnormal number of erythroid precursors (HP:0012131) | 3.84935353 |
| 12 | Pancreatic fibrosis (HP:0100732) | 3.80362216 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.79704868 |
| 14 | Pancreatic cysts (HP:0001737) | 3.78686768 |
| 15 | Hepatic necrosis (HP:0002605) | 3.61048605 |
| 16 | Increased CSF lactate (HP:0002490) | 3.60626008 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.52029184 |
| 18 | Macrocytic anemia (HP:0001972) | 3.49096111 |
| 19 | Reticulocytopenia (HP:0001896) | 3.47412377 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 3.36866997 |
| 21 | Abnormality of the pons (HP:0007361) | 3.31285980 |
| 22 | Hypoplasia of the pons (HP:0012110) | 3.25665341 |
| 23 | Type II lissencephaly (HP:0007260) | 3.19872031 |
| 24 | Abnormal biliary tract physiology (HP:0012439) | 3.10475572 |
| 25 | Bile duct proliferation (HP:0001408) | 3.10475572 |
| 26 | Cystic liver disease (HP:0006706) | 3.06035286 |
| 27 | Cerebral edema (HP:0002181) | 3.00443617 |
| 28 | Colon cancer (HP:0003003) | 2.98998446 |
| 29 | Chronic hepatic failure (HP:0100626) | 2.95859458 |
| 30 | Increased muscle lipid content (HP:0009058) | 2.93015679 |
| 31 | Supernumerary spleens (HP:0009799) | 2.92051929 |
| 32 | Exertional dyspnea (HP:0002875) | 2.86480660 |
| 33 | Abnormality of renal resorption (HP:0011038) | 2.81305914 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.72300978 |
| 35 | Cerebellar dysplasia (HP:0007033) | 2.65595838 |
| 36 | Abnormality of urine glucose concentration (HP:0011016) | 2.61878054 |
| 37 | Glycosuria (HP:0003076) | 2.61878054 |
| 38 | Male pseudohermaphroditism (HP:0000037) | 2.60049706 |
| 39 | Microvesicular hepatic steatosis (HP:0001414) | 2.59909952 |
| 40 | Abnormality of the labia minora (HP:0012880) | 2.57033232 |
| 41 | Oligodactyly (hands) (HP:0001180) | 2.55393334 |
| 42 | Anomalous pulmonary venous return (HP:0010772) | 2.47160515 |
| 43 | Exercise intolerance (HP:0003546) | 2.45699056 |
| 44 | Respiratory failure (HP:0002878) | 2.43438798 |
| 45 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.38264934 |
| 46 | Medial flaring of the eyebrow (HP:0010747) | 2.38065911 |
| 47 | Hyperglycinemia (HP:0002154) | 2.35939858 |
| 48 | Long foot (HP:0001833) | 2.35748231 |
| 49 | Optic nerve coloboma (HP:0000588) | 2.32482249 |
| 50 | Increased serum lactate (HP:0002151) | 2.28480414 |
| 51 | Hyperphosphaturia (HP:0003109) | 2.27705839 |
| 52 | Anencephaly (HP:0002323) | 2.25590397 |
| 53 | Cerebral hypomyelination (HP:0006808) | 2.25588427 |
| 54 | Hip dysplasia (HP:0001385) | 2.23949281 |
| 55 | Pendular nystagmus (HP:0012043) | 2.18427863 |
| 56 | Sclerocornea (HP:0000647) | 2.18215857 |
| 57 | Oligodactyly (HP:0012165) | 2.14572724 |
| 58 | Absent thumb (HP:0009777) | 2.13857675 |
| 59 | Generalized aminoaciduria (HP:0002909) | 2.13671448 |
| 60 | Abnormality of midbrain morphology (HP:0002418) | 2.12064153 |
| 61 | Molar tooth sign on MRI (HP:0002419) | 2.12064153 |
| 62 | Hypomagnesemia (HP:0002917) | 2.08979067 |
| 63 | Abnormality of the pulmonary veins (HP:0011718) | 2.08935245 |
| 64 | Congenital hepatic fibrosis (HP:0002612) | 2.07277363 |
| 65 | Respiratory difficulties (HP:0002880) | 2.04706949 |
| 66 | Muscle fiber atrophy (HP:0100295) | 2.04093862 |
| 67 | Optic disc pallor (HP:0000543) | 2.04078361 |
| 68 | Hyperglycinuria (HP:0003108) | 2.03754628 |
| 69 | Abnormal number of incisors (HP:0011064) | 2.01773245 |
| 70 | Rib fusion (HP:0000902) | 2.01254870 |
| 71 | Nephronophthisis (HP:0000090) | 2.00794526 |
| 72 | Gait imbalance (HP:0002141) | 2.00163310 |
| 73 | Lethargy (HP:0001254) | 2.00086040 |
| 74 | Lactic acidosis (HP:0003128) | 1.99689065 |
| 75 | Pallor (HP:0000980) | 1.99518236 |
| 76 | Type 2 muscle fiber atrophy (HP:0003554) | 1.97581329 |
| 77 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.96643115 |
| 78 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.96643115 |
| 79 | Abnormal ciliary motility (HP:0012262) | 1.94964657 |
| 80 | Abnormality of lateral ventricle (HP:0030047) | 1.94559308 |
| 81 | Blindness (HP:0000618) | 1.94239239 |
| 82 | Meckel diverticulum (HP:0002245) | 1.93366848 |
| 83 | Congenital primary aphakia (HP:0007707) | 1.92639308 |
| 84 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92026059 |
| 85 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91823509 |
| 86 | Hypoplasia of the radius (HP:0002984) | 1.87298169 |
| 87 | Anophthalmia (HP:0000528) | 1.86714776 |
| 88 | Abnormality of the ileum (HP:0001549) | 1.86204771 |
| 89 | 3-Methylglutaconic aciduria (HP:0003535) | 1.85864660 |
| 90 | Abnormality of the anterior horn cell (HP:0006802) | 1.83641060 |
| 91 | Degeneration of anterior horn cells (HP:0002398) | 1.83641060 |
| 92 | Myokymia (HP:0002411) | 1.82833747 |
| 93 | Volvulus (HP:0002580) | 1.81062636 |
| 94 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.79697459 |
| 95 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76795704 |
| 96 | Depressed nasal ridge (HP:0000457) | 1.74852976 |
| 97 | Abnormal hair whorl (HP:0010721) | 1.73999467 |
| 98 | Tachypnea (HP:0002789) | 1.73171425 |
| 99 | Abnormal urine phosphate concentration (HP:0012599) | 1.72866786 |
| 100 | Lissencephaly (HP:0001339) | 1.72775207 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.51058274 |
| 2 | STK16 | 3.73273921 |
| 3 | VRK1 | 3.71228283 |
| 4 | BUB1 | 3.15208845 |
| 5 | ZAK | 2.93798955 |
| 6 | BRSK1 | 2.71383435 |
| 7 | BCKDK | 2.53048977 |
| 8 | CDC7 | 2.40634893 |
| 9 | NME1 | 2.33627672 |
| 10 | SRPK1 | 2.12057240 |
| 11 | PBK | 2.07621192 |
| 12 | MKNK2 | 1.96901751 |
| 13 | MAP4K2 | 1.96309703 |
| 14 | DYRK2 | 1.92300862 |
| 15 | NME2 | 1.88639878 |
| 16 | CDK8 | 1.79232143 |
| 17 | BRSK2 | 1.77278337 |
| 18 | PASK | 1.57853419 |
| 19 | STK4 | 1.54200298 |
| 20 | WNK4 | 1.47187054 |
| 21 | TLK1 | 1.43760232 |
| 22 | AURKA | 1.40322455 |
| 23 | NEK1 | 1.32197342 |
| 24 | MAP3K9 | 1.30312842 |
| 25 | PLK1 | 1.24969140 |
| 26 | DAPK3 | 1.24911528 |
| 27 | TTK | 1.20922367 |
| 28 | BMPR1B | 1.20642231 |
| 29 | WNK1 | 1.18877052 |
| 30 | PLK4 | 1.18151640 |
| 31 | PIM2 | 1.18079878 |
| 32 | PAK4 | 1.17531365 |
| 33 | AURKB | 1.17418859 |
| 34 | MKNK1 | 1.15872391 |
| 35 | WEE1 | 1.15684647 |
| 36 | RPS6KA6 | 1.13366496 |
| 37 | PRKCG | 1.13053566 |
| 38 | PLK3 | 1.12026484 |
| 39 | NEK2 | 1.11468565 |
| 40 | RPS6KL1 | 1.10820563 |
| 41 | RPS6KC1 | 1.10820563 |
| 42 | TNK2 | 1.04091905 |
| 43 | INSRR | 1.00929998 |
| 44 | GRK1 | 0.99790995 |
| 45 | WNK3 | 0.99583698 |
| 46 | RPS6KA5 | 0.96376327 |
| 47 | PKN1 | 0.95884706 |
| 48 | NTRK2 | 0.92412509 |
| 49 | MST4 | 0.85628250 |
| 50 | MAP2K2 | 0.85180562 |
| 51 | CASK | 0.84020098 |
| 52 | ADRBK2 | 0.81336131 |
| 53 | UHMK1 | 0.80105012 |
| 54 | MELK | 0.76617344 |
| 55 | MAP3K4 | 0.75474595 |
| 56 | STK39 | 0.75297349 |
| 57 | TYRO3 | 0.74270988 |
| 58 | MARK3 | 0.70271487 |
| 59 | CSNK2A2 | 0.69986671 |
| 60 | EIF2AK1 | 0.66086068 |
| 61 | PIK3CG | 0.65568319 |
| 62 | STK11 | 0.65008490 |
| 63 | PAK6 | 0.64147354 |
| 64 | PRKCQ | 0.64131493 |
| 65 | MAP2K7 | 0.62203013 |
| 66 | STK24 | 0.62007545 |
| 67 | ABL2 | 0.61922024 |
| 68 | EPHA3 | 0.61086076 |
| 69 | PRKACA | 0.57270609 |
| 70 | IRAK4 | 0.57062489 |
| 71 | CAMK1 | 0.56239183 |
| 72 | DDR2 | 0.56111883 |
| 73 | PAK3 | 0.54768500 |
| 74 | PRKCH | 0.53181112 |
| 75 | TSSK6 | 0.52938785 |
| 76 | GRK7 | 0.52541386 |
| 77 | MAPK15 | 0.51243160 |
| 78 | IKBKB | 0.50213107 |
| 79 | TNIK | 0.49727138 |
| 80 | MINK1 | 0.49157246 |
| 81 | NLK | 0.48030098 |
| 82 | PAK1 | 0.45911069 |
| 83 | CSNK1E | 0.45079932 |
| 84 | CSNK2A1 | 0.44904654 |
| 85 | DYRK3 | 0.44535727 |
| 86 | BMX | 0.44365126 |
| 87 | MAP3K11 | 0.44052998 |
| 88 | ATR | 0.43734020 |
| 89 | PRKACG | 0.42827768 |
| 90 | LRRK2 | 0.41020785 |
| 91 | RPS6KA1 | 0.40607536 |
| 92 | CCNB1 | 0.39117835 |
| 93 | PHKG2 | 0.39106552 |
| 94 | PHKG1 | 0.39106552 |
| 95 | CAMK4 | 0.37538529 |
| 96 | PLK2 | 0.36629735 |
| 97 | PRKCD | 0.36045389 |
| 98 | SGK1 | 0.35185944 |
| 99 | MAP3K8 | 0.34661971 |
| 100 | MUSK | 0.34557650 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.19691529 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.74222616 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.19079079 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.39841847 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.91708340 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.85422844 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.84664990 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.60839270 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.59241338 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.39199000 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.92565732 |
| 12 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.85515485 |
| 13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.82530275 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.72714598 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 1.71563196 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.65519110 |
| 17 | Spliceosome_Homo sapiens_hsa03040 | 1.62814667 |
| 18 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.57203875 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.51261868 |
| 20 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.48690526 |
| 21 | Mismatch repair_Homo sapiens_hsa03430 | 1.47553153 |
| 22 | RNA transport_Homo sapiens_hsa03013 | 1.40420164 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.35556207 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.29077994 |
| 25 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.28420784 |
| 26 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.28331700 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.22824815 |
| 28 | Alcoholism_Homo sapiens_hsa05034 | 1.20903208 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.19599221 |
| 30 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.15170942 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.11127711 |
| 32 | DNA replication_Homo sapiens_hsa03030 | 1.08767115 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.03917461 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.03678680 |
| 35 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.97067888 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.94623227 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.94190939 |
| 38 | Asthma_Homo sapiens_hsa05310 | 0.93858363 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 0.89746311 |
| 40 | Allograft rejection_Homo sapiens_hsa05330 | 0.86401478 |
| 41 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.85241008 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 0.85240876 |
| 43 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.82613989 |
| 44 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82308282 |
| 45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.81727469 |
| 46 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.79686611 |
| 47 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.79443118 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 0.76738673 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.76183054 |
| 50 | Metabolic pathways_Homo sapiens_hsa01100 | 0.73466587 |
| 51 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.73139655 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.69749706 |
| 53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.69535878 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.69159800 |
| 55 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.68956363 |
| 56 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.68366116 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67755711 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.67014607 |
| 59 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.64313671 |
| 60 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.64263821 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61764303 |
| 62 | Cell cycle_Homo sapiens_hsa04110 | 0.58518534 |
| 63 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56183832 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.54643132 |
| 65 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.54319116 |
| 66 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.53630272 |
| 67 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.52436660 |
| 68 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50589528 |
| 69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.48318112 |
| 70 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.47743102 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47242629 |
| 72 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.46040094 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.44166271 |
| 74 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44141848 |
| 75 | Mineral absorption_Homo sapiens_hsa04978 | 0.38490913 |
| 76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.38227192 |
| 77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38010463 |
| 78 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.37774280 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.37497178 |
| 80 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.37232396 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36093832 |
| 82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.33928031 |
| 83 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.33727432 |
| 84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29067279 |
| 85 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.27807860 |
| 86 | Insulin secretion_Homo sapiens_hsa04911 | 0.27269512 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.27189758 |
| 88 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.25480925 |
| 89 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.24181557 |
| 90 | Salivary secretion_Homo sapiens_hsa04970 | 0.22515622 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.22481011 |
| 92 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.22156062 |
| 93 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.21197254 |
| 94 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.20719690 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.19558232 |
| 96 | Carbon metabolism_Homo sapiens_hsa01200 | 0.19519394 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.19311969 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.18289088 |
| 99 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.17938281 |
| 100 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.15989041 |

