DZIP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synapsis (GO:0007129)6.88060028
2male meiosis I (GO:0007141)6.30638929
3piRNA metabolic process (GO:0034587)6.21042567
4chromosome organization involved in meiosis (GO:0070192)5.55745769
5neuron cell-cell adhesion (GO:0007158)5.52062067
6DNA methylation involved in gamete generation (GO:0043046)5.33240308
7cilium or flagellum-dependent cell motility (GO:0001539)5.32665145
8vocalization behavior (GO:0071625)5.21579241
9male meiosis (GO:0007140)5.16787880
10regulation of short-term neuronal synaptic plasticity (GO:0048172)5.10997000
11meiosis I (GO:0007127)4.90655466
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.84145977
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.80961049
14epithelial cilium movement (GO:0003351)4.80720037
15synaptonemal complex assembly (GO:0007130)4.78842184
16regulation of meiosis I (GO:0060631)4.78112898
17protein localization to synapse (GO:0035418)4.73415876
18cilium movement (GO:0003341)4.73350705
19axonemal dynein complex assembly (GO:0070286)4.67099224
20positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.64210268
21layer formation in cerebral cortex (GO:0021819)4.61298773
22ionotropic glutamate receptor signaling pathway (GO:0035235)4.60442358
23epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.59736990
24synaptonemal complex organization (GO:0070193)4.54845763
25synaptic vesicle exocytosis (GO:0016079)4.50652617
26locomotory exploration behavior (GO:0035641)4.50300139
27regulation of glutamate receptor signaling pathway (GO:1900449)4.46563915
28neuron recognition (GO:0008038)4.44673653
29axoneme assembly (GO:0035082)4.40533938
30glutamate receptor signaling pathway (GO:0007215)4.33872257
31meiotic nuclear division (GO:0007126)4.30688305
32intraciliary transport (GO:0042073)4.22978223
33meiotic chromosome segregation (GO:0045132)4.15305633
34axonal fasciculation (GO:0007413)4.14270202
35dendritic spine morphogenesis (GO:0060997)4.13371703
36synaptic vesicle maturation (GO:0016188)4.11517746
37regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.08279497
38regulation of synaptic vesicle exocytosis (GO:2000300)4.04917912
39exploration behavior (GO:0035640)4.00513059
40regulation of cilium movement (GO:0003352)3.95659428
41synaptic transmission, glutamatergic (GO:0035249)3.91902537
42gamma-aminobutyric acid signaling pathway (GO:0007214)3.91004444
43presynaptic membrane assembly (GO:0097105)3.89333508
44glutamate secretion (GO:0014047)3.89212174
45postsynaptic membrane organization (GO:0001941)3.86216412
46neuron-neuron synaptic transmission (GO:0007270)3.85083407
47sister chromatid cohesion (GO:0007062)3.83890299
48regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.80477181
49neurotransmitter secretion (GO:0007269)3.78714618
50protein localization to cilium (GO:0061512)3.76947676
51transmission of nerve impulse (GO:0019226)3.69735037
52establishment of nucleus localization (GO:0040023)3.68167164
53positive regulation of synapse maturation (GO:0090129)3.66943213
54positive regulation of dendritic spine morphogenesis (GO:0061003)3.66704907
55DNA synthesis involved in DNA repair (GO:0000731)3.66597083
56neuronal action potential propagation (GO:0019227)3.64838685
57regulation of long-term neuronal synaptic plasticity (GO:0048169)3.64078264
58positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.59419336
59presynaptic membrane organization (GO:0097090)3.58780650
60regulation of synaptic vesicle transport (GO:1902803)3.58116208
61regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.56024973
62positive regulation of synapse assembly (GO:0051965)3.52430112
63reciprocal meiotic recombination (GO:0007131)3.52229994
64reciprocal DNA recombination (GO:0035825)3.52229994
65gamma-aminobutyric acid transport (GO:0015812)3.51203253
66neurotransmitter-gated ion channel clustering (GO:0072578)3.50627399
67regulation of microtubule-based movement (GO:0060632)3.49369949
68negative regulation of synaptic transmission, GABAergic (GO:0032229)3.47857878
69resolution of meiotic recombination intermediates (GO:0000712)3.47466588
70regulation of neuronal synaptic plasticity (GO:0048168)3.47445929
71positive regulation of meiosis (GO:0045836)3.47247637
72meiotic cell cycle process (GO:1903046)3.46075605
73regulation of dendritic spine morphogenesis (GO:0061001)3.44425312
74regulation of excitatory postsynaptic membrane potential (GO:0060079)3.43104981
75G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.41825483
76long-term memory (GO:0007616)3.38968194
77regulation of postsynaptic membrane potential (GO:0060078)3.36672224
78cilium organization (GO:0044782)3.36480058
79cilium assembly (GO:0042384)3.35420693
80histone H3-K36 demethylation (GO:0070544)3.35260310
81central nervous system projection neuron axonogenesis (GO:0021952)3.34567940
82synaptic vesicle docking involved in exocytosis (GO:0016081)3.34457996
83startle response (GO:0001964)3.32692518
84dendrite morphogenesis (GO:0048813)3.31730945
85cilium morphogenesis (GO:0060271)3.31528427
86proline transport (GO:0015824)3.26662283
87neurotransmitter transport (GO:0006836)3.26133244
88nonmotile primary cilium assembly (GO:0035058)3.25191327
89positive regulation of membrane potential (GO:0045838)3.22911433
90histone H3-K9 demethylation (GO:0033169)3.22560240
91positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.21453036
92cerebellar Purkinje cell differentiation (GO:0021702)3.21431619
93response to histamine (GO:0034776)3.20255788
94positive regulation of synaptic transmission, GABAergic (GO:0032230)3.19770462
95regulation of synapse maturation (GO:0090128)3.19338865
96positive regulation of meiotic cell cycle (GO:0051446)3.19268680
97synapse assembly (GO:0007416)3.17675281
98regulation of synaptic transmission, glutamatergic (GO:0051966)3.15477458
99positive regulation of dendritic spine development (GO:0060999)3.15365954
100regulation of DNA endoreduplication (GO:0032875)3.12104274
101regulation of vesicle fusion (GO:0031338)3.10224157
102cerebellar granule cell differentiation (GO:0021707)3.09773827
103regulation of respiratory system process (GO:0044065)3.09175419
104motile cilium assembly (GO:0044458)3.08768099
105membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.07572763
106synaptic vesicle endocytosis (GO:0048488)3.06545796
107cell migration in hindbrain (GO:0021535)3.04817191
108behavioral defense response (GO:0002209)3.03281583
109behavioral fear response (GO:0001662)3.03281583
110innervation (GO:0060384)3.02810985
111regulation of synapse assembly (GO:0051963)3.01768966
112embryonic body morphogenesis (GO:0010172)3.01697030
113histone H2A acetylation (GO:0043968)3.01394511
114auditory behavior (GO:0031223)2.99152222
115dendrite development (GO:0016358)2.96901432
116regulation of synapse structural plasticity (GO:0051823)2.95852696
117regulation of dendritic spine development (GO:0060998)2.95592924
118photoreceptor cell maintenance (GO:0045494)2.95162398
119long-term synaptic potentiation (GO:0060291)2.94879632
120regulation of neurotransmitter levels (GO:0001505)2.94469220
121synapse organization (GO:0050808)2.93796572
122negative regulation of gene silencing (GO:0060969)2.93298954
123learning (GO:0007612)2.91376644
124membrane hyperpolarization (GO:0060081)2.91142100
125positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.91007621
126cerebral cortex radially oriented cell migration (GO:0021799)2.90415131
127mating behavior (GO:0007617)2.90285552
128sex differentiation (GO:0007548)2.89695073
129membrane depolarization (GO:0051899)2.88976143
130response to auditory stimulus (GO:0010996)2.87620879
131regulation of neurotransmitter secretion (GO:0046928)2.87403199
132neuronal ion channel clustering (GO:0045161)2.86523122
133regulation of synaptic transmission, GABAergic (GO:0032228)2.86419117
134regulation of respiratory gaseous exchange (GO:0043576)2.86211749
135regulation of synaptic plasticity (GO:0048167)2.86109190
136regulation of synapse organization (GO:0050807)2.85798621
137fear response (GO:0042596)2.85451989
138mitotic sister chromatid cohesion (GO:0007064)2.83780441
139prepulse inhibition (GO:0060134)2.82167900
140left/right axis specification (GO:0070986)2.81175343
141microtubule bundle formation (GO:0001578)2.81161428
142negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.81156488
143body morphogenesis (GO:0010171)2.80125502
144intraspecies interaction between organisms (GO:0051703)2.79676038
145social behavior (GO:0035176)2.79676038
146nucleus localization (GO:0051647)2.78560556
147mechanosensory behavior (GO:0007638)2.77608266
148cellular component assembly involved in morphogenesis (GO:0010927)2.76872272
149left/right pattern formation (GO:0060972)2.75332775
150righting reflex (GO:0060013)2.73444434
151cochlea development (GO:0090102)2.73334347
152membrane depolarization during action potential (GO:0086010)2.72779154
153gene silencing by RNA (GO:0031047)2.66523898
154brain morphogenesis (GO:0048854)2.62143100
155retinal cone cell development (GO:0046549)2.61097022
156histone H4-K12 acetylation (GO:0043983)2.59400257
157genitalia morphogenesis (GO:0035112)2.57724341
158hindbrain development (GO:0030902)2.56824538
159pyrimidine nucleobase catabolic process (GO:0006208)2.54785097
160central nervous system neuron axonogenesis (GO:0021955)2.53638030
161ventricular system development (GO:0021591)2.47569535
162smoothened signaling pathway (GO:0007224)2.47508675
163protein polyglutamylation (GO:0018095)2.46237508
164establishment of protein localization to Golgi (GO:0072600)2.44019543
165microtubule-based movement (GO:0007018)2.41339985
166hippocampus development (GO:0021766)2.40935736
167spermatid development (GO:0007286)2.38694543
168limb development (GO:0060173)2.37320656
169appendage development (GO:0048736)2.37320656
170spinal cord motor neuron differentiation (GO:0021522)2.36303603
171DNA methylation (GO:0006306)2.35584037
172DNA alkylation (GO:0006305)2.35584037
173neural tube formation (GO:0001841)2.34308414
174protein targeting to Golgi (GO:0000042)2.32095329
175regulation of collateral sprouting (GO:0048670)2.30320620
176centriole replication (GO:0007099)2.29328900
177regulation of glucokinase activity (GO:0033131)2.28718005
178regulation of hexokinase activity (GO:1903299)2.28718005
179somite rostral/caudal axis specification (GO:0032525)2.27816986
180acrosome assembly (GO:0001675)2.27553433
181apical protein localization (GO:0045176)2.25987793
182nucleobase catabolic process (GO:0046113)2.23208205
183female gamete generation (GO:0007292)2.22456122
184mismatch repair (GO:0006298)2.20851511
185positive regulation of response to oxidative stress (GO:1902884)2.19229058
186positive regulation of cellular response to oxidative stress (GO:1900409)2.19229058
187behavioral response to nicotine (GO:0035095)2.18701697
188negative regulation of cytosolic calcium ion concentration (GO:0051481)2.18154715

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.95313084
2GBX2_23144817_ChIP-Seq_PC3_Human3.89579237
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.97473686
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85564388
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71593422
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.58372131
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53531664
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41774415
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41774415
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.39337635
11TAF15_26573619_Chip-Seq_HEK293_Human2.38351007
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.36224073
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.34214403
14REST_21632747_ChIP-Seq_MESCs_Mouse2.33808772
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.33040339
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.27161513
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.26291958
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.25861408
19MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12696366
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.08986334
21CTBP1_25329375_ChIP-Seq_LNCAP_Human2.07823227
22ZFP57_27257070_Chip-Seq_ESCs_Mouse2.06245837
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.06137755
24IGF1R_20145208_ChIP-Seq_DFB_Human2.03222572
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.02730012
26FUS_26573619_Chip-Seq_HEK293_Human2.00012188
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.99135077
28ZNF274_21170338_ChIP-Seq_K562_Hela1.98393421
29EZH2_27294783_Chip-Seq_ESCs_Mouse1.94171969
30SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.91471763
31AR_21572438_ChIP-Seq_LNCaP_Human1.90747694
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.89704149
33DROSHA_22980978_ChIP-Seq_HELA_Human1.88131503
34SUZ12_27294783_Chip-Seq_ESCs_Mouse1.88054033
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84989909
36SMAD4_21799915_ChIP-Seq_A2780_Human1.82089903
37P300_19829295_ChIP-Seq_ESCs_Human1.81519050
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.77867299
39RARB_27405468_Chip-Seq_BRAIN_Mouse1.77689653
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.76671910
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73088014
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.71994943
43GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.70591399
44RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.65536524
45FLI1_27457419_Chip-Seq_LIVER_Mouse1.64489808
46BCAT_22108803_ChIP-Seq_LS180_Human1.63518484
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60809201
48RNF2_27304074_Chip-Seq_NSC_Mouse1.60787285
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.57148672
50SMAD3_21741376_ChIP-Seq_EPCs_Human1.55207506
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53749423
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52658958
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.46213694
54SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45509602
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44528884
56SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43086554
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40760298
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.40337493
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39422305
60CBP_20019798_ChIP-Seq_JUKART_Human1.39422305
61IKZF1_21737484_ChIP-ChIP_HCT116_Human1.38901806
62* STAT3_23295773_ChIP-Seq_U87_Human1.35291583
63RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.34613687
64KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34502972
65SOX2_21211035_ChIP-Seq_LN229_Gbm1.34409825
66AR_25329375_ChIP-Seq_VCAP_Human1.30097714
67ER_23166858_ChIP-Seq_MCF-7_Human1.29962202
68EWS_26573619_Chip-Seq_HEK293_Human1.29151230
69BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.28991672
70AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.28201450
71TCF4_22108803_ChIP-Seq_LS180_Human1.27114425
72TP53_16413492_ChIP-PET_HCT116_Human1.25780306
73TCF4_23295773_ChIP-Seq_U87_Human1.24051553
74UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.23850189
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23344730
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23114052
77RING1B_27294783_Chip-Seq_ESCs_Mouse1.22894931
78GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21205370
79CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21006007
80RBPJ_22232070_ChIP-Seq_NCS_Mouse1.19635405
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.19278289
82SALL1_21062744_ChIP-ChIP_HESCs_Human1.18541201
83POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17940338
84TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17940338
85RUNX2_22187159_ChIP-Seq_PCA_Human1.17723347
86TP53_22573176_ChIP-Seq_HFKS_Human1.17463431
87SMAD4_21741376_ChIP-Seq_EPCs_Human1.16428367
88YAP1_20516196_ChIP-Seq_MESCs_Mouse1.16027702
89AR_19668381_ChIP-Seq_PC3_Human1.15281106
90MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14746875
91RING1B_27294783_Chip-Seq_NPCs_Mouse1.13958112
92HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13135162
93* TAL1_26923725_Chip-Seq_HPCs_Mouse1.10558431
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10187451
95P53_22387025_ChIP-Seq_ESCs_Mouse1.09739200
96TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09605256
97NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09229847
98ARNT_22903824_ChIP-Seq_MCF-7_Human1.08065169
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.07497072
100JUN_21703547_ChIP-Seq_K562_Human1.07486741
101NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07324679
102EZH2_27294783_Chip-Seq_NPCs_Mouse1.06448404
103CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06364208
104SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06204494
105TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.05855052
106EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05726238
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05556559
108MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05106696
109MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03846132
110TP53_18474530_ChIP-ChIP_U2OS_Human1.03499315
111NFE2_27457419_Chip-Seq_LIVER_Mouse1.03213649
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.02890529
113PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02782801
114POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02565874
115SOX9_26525672_Chip-Seq_HEART_Mouse1.01864633
116STAT3_18555785_Chip-Seq_ESCs_Mouse1.01817148
117SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01486012
118E2F1_18555785_Chip-Seq_ESCs_Mouse1.01120602
119EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00273121
120* SMAD_19615063_ChIP-ChIP_OVARY_Human1.00173615
121PRDM14_20953172_ChIP-Seq_ESCs_Human0.99017856
122NANOG_19829295_ChIP-Seq_ESCs_Human0.98822711
123SOX2_19829295_ChIP-Seq_ESCs_Human0.98822711
124FLI1_21867929_ChIP-Seq_TH2_Mouse0.98730125
125P53_22127205_ChIP-Seq_FIBROBLAST_Human0.98577095
126VDR_22108803_ChIP-Seq_LS180_Human0.98356243
127FOXA1_21572438_ChIP-Seq_LNCaP_Human0.97921625
128EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97826678
129SMAD3_21741376_ChIP-Seq_ESCs_Human0.97730989
130TBL1_22424771_ChIP-Seq_293T_Human0.97594126
131KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.97139811
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.95951711

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.72785203
2MP0003880_abnormal_central_pattern4.72658758
3MP0003635_abnormal_synaptic_transmissio3.60628163
4MP0009745_abnormal_behavioral_response3.02010141
5MP0005423_abnormal_somatic_nervous2.99937733
6MP0004270_analgesia2.94836764
7MP0009046_muscle_twitch2.91091994
8MP0002063_abnormal_learning/memory/cond2.90075382
9MP0002064_seizures2.72469477
10MP0001968_abnormal_touch/_nociception2.58231875
11MP0002572_abnormal_emotion/affect_behav2.57654864
12MP0003787_abnormal_imprinting2.51343867
13MP0001486_abnormal_startle_reflex2.46141525
14MP0003122_maternal_imprinting2.40874603
15MP0002272_abnormal_nervous_system2.28752877
16MP0000778_abnormal_nervous_system2.28640703
17MP0002734_abnormal_mechanical_nocicepti2.26096576
18MP0002735_abnormal_chemical_nociception2.25433513
19MP0006276_abnormal_autonomic_nervous2.24139415
20MP0001440_abnormal_grooming_behavior2.17119489
21MP0002184_abnormal_innervation2.00542480
22MP0002736_abnormal_nociception_after1.97693333
23MP0002160_abnormal_reproductive_system1.96644181
24MP0002067_abnormal_sensory_capabilities1.94651315
25MP0001501_abnormal_sleep_pattern1.90163170
26MP0003890_abnormal_embryonic-extraembry1.88619733
27MP0002210_abnormal_sex_determination1.87660353
28MP0001529_abnormal_vocalization1.87067320
29MP0003121_genomic_imprinting1.85154115
30MP0004133_heterotaxia1.84664418
31MP0000383_abnormal_hair_follicle1.84487817
32MP0002557_abnormal_social/conspecific_i1.84191496
33MP0001188_hyperpigmentation1.83153783
34MP0002733_abnormal_thermal_nociception1.81878552
35MP0005645_abnormal_hypothalamus_physiol1.81354190
36MP0001929_abnormal_gametogenesis1.76677328
37MP0005386_behavior/neurological_phenoty1.74722406
38MP0004924_abnormal_behavior1.74722406
39MP0000569_abnormal_digit_pigmentation1.74513659
40MP0003698_abnormal_male_reproductive1.69771429
41MP0001970_abnormal_pain_threshold1.66447146
42MP0002822_catalepsy1.62992848
43MP0008058_abnormal_DNA_repair1.61177801
44MP0000955_abnormal_spinal_cord1.58089744
45MP0000427_abnormal_hair_cycle1.54441064
46MP0009780_abnormal_chondrocyte_physiolo1.52556769
47MP0010678_abnormal_skin_adnexa1.52398134
48MP0008569_lethality_at_weaning1.50288816
49MP0008995_early_reproductive_senescence1.50236216
50MP0005646_abnormal_pituitary_gland1.50024345
51MP0001145_abnormal_male_reproductive1.49689246
52MP0001984_abnormal_olfaction1.49279260
53MP0004811_abnormal_neuron_physiology1.45922077
54MP0000653_abnormal_sex_gland1.43891482
55MP0002882_abnormal_neuron_morphology1.43626236
56MP0003119_abnormal_digestive_system1.39632998
57MP0003937_abnormal_limbs/digits/tail_de1.36782620
58MP0003123_paternal_imprinting1.36738844
59MP0002066_abnormal_motor_capabilities/c1.31630620
60MP0002152_abnormal_brain_morphology1.29044385
61MP0001905_abnormal_dopamine_level1.28659565
62MP0004142_abnormal_muscle_tone1.27585170
63MP0002102_abnormal_ear_morphology1.26362189
64MP0005389_reproductive_system_phenotype1.25886333
65MP0000631_abnormal_neuroendocrine_gland1.25771834
66MP0004885_abnormal_endolymph1.24208292
67MP0003329_amyloid_beta_deposits1.17575563
68MP0008057_abnormal_DNA_replication1.16820491
69MP0002653_abnormal_ependyma_morphology1.14902836
70MP0001502_abnormal_circadian_rhythm1.14380341
71MP0005551_abnormal_eye_electrophysiolog1.13486772
72MP0004742_abnormal_vestibular_system1.13355770
73MP0006072_abnormal_retinal_apoptosis1.11202834
74MP0003646_muscle_fatigue1.09162181
75MP0004145_abnormal_muscle_electrophysio1.05953064
76MP0008877_abnormal_DNA_methylation1.04536809
77MP0002233_abnormal_nose_morphology1.04073561
78MP0003861_abnormal_nervous_system1.01207491
79MP0000647_abnormal_sebaceous_gland1.00141327
80MP0005409_darkened_coat_color1.00042475
81MP0005394_taste/olfaction_phenotype1.00033594
82MP0005499_abnormal_olfactory_system1.00033594
83MP0003136_yellow_coat_color0.99987177
84MP0002752_abnormal_somatic_nervous0.97240934
85MP0004858_abnormal_nervous_system0.97239005
86MP0004043_abnormal_pH_regulation0.97089676
87MP0001485_abnormal_pinna_reflex0.95306484
88MP0005174_abnormal_tail_pigmentation0.95280259
89MP0001963_abnormal_hearing_physiology0.94253812
90MP0006292_abnormal_olfactory_placode0.93419522
91MP0002909_abnormal_adrenal_gland0.89990799
92MP0002161_abnormal_fertility/fecundity0.89210550
93MP0001293_anophthalmia0.88014110
94MP0001299_abnormal_eye_distance/0.87978770
95MP0002928_abnormal_bile_duct0.86452717
96MP0002638_abnormal_pupillary_reflex0.86176623
97MP0003631_nervous_system_phenotype0.85813759
98MP0003195_calcinosis0.85792396
99MP0003633_abnormal_nervous_system0.85321874
100MP0002938_white_spotting0.84205542
101MP0005187_abnormal_penis_morphology0.83671391
102MP0002229_neurodegeneration0.83152203
103MP0001177_atelectasis0.81635415
104MP0003632_abnormal_nervous_system0.81218309
105MP0010386_abnormal_urinary_bladder0.79841231
106MP0009703_decreased_birth_body0.79676949
107MP0002069_abnormal_eating/drinking_beha0.79316336
108MP0003137_abnormal_impulse_conducting0.79149820
109MP0003879_abnormal_hair_cell0.78858064
110MP0000026_abnormal_inner_ear0.78425337
111MP0002084_abnormal_developmental_patter0.77509915
112MP0000751_myopathy0.76748459
113MP0003385_abnormal_body_wall0.76737410
114MP0003938_abnormal_ear_development0.76624751
115MP0000537_abnormal_urethra_morphology0.76400762
116MP0003634_abnormal_glial_cell0.76311899
117MP0005171_absent_coat_pigmentation0.76286013
118MP0005248_abnormal_Harderian_gland0.75764483
119MP0005379_endocrine/exocrine_gland_phen0.75645741
120MP0002234_abnormal_pharynx_morphology0.75133074
121MP0002837_dystrophic_cardiac_calcinosis0.72497566
122MP0003283_abnormal_digestive_organ0.70312216
123MP0001943_abnormal_respiration0.69862353
124MP0004085_abnormal_heartbeat0.69418805
125MP0005623_abnormal_meninges_morphology0.69065505
126MP0002751_abnormal_autonomic_nervous0.67550387
127MP0004215_abnormal_myocardial_fiber0.67224657
128MP0004233_abnormal_muscle_weight0.66858907
129MP0005253_abnormal_eye_physiology0.66413928
130MP0008789_abnormal_olfactory_epithelium0.64501865
131MP0000920_abnormal_myelination0.63630844
132MP0002082_postnatal_lethality0.63109731
133MP0010770_preweaning_lethality0.63109731

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.27317843
2Focal seizures (HP:0007359)4.59624102
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.39434081
4Epileptic encephalopathy (HP:0200134)4.24458310
5Abnormal respiratory epithelium morphology (HP:0012253)4.19812908
6Abnormal respiratory motile cilium morphology (HP:0005938)4.19812908
7Myokymia (HP:0002411)4.13684668
8Febrile seizures (HP:0002373)4.02139865
9Atonic seizures (HP:0010819)3.92278008
10Visual hallucinations (HP:0002367)3.78069926
11Rhinitis (HP:0012384)3.69261207
12Volvulus (HP:0002580)3.67714982
13Nephronophthisis (HP:0000090)3.64205025
14Broad-based gait (HP:0002136)3.57323799
15Progressive cerebellar ataxia (HP:0002073)3.56179569
16Absence seizures (HP:0002121)3.41677726
17Pancreatic fibrosis (HP:0100732)3.35401703
18Tubulointerstitial nephritis (HP:0001970)3.32156017
19Excessive salivation (HP:0003781)3.25339488
20Drooling (HP:0002307)3.25339488
21Hyperventilation (HP:0002883)3.14510888
22Abnormality of the renal medulla (HP:0100957)3.13890790
23Dialeptic seizures (HP:0011146)3.13527684
24Oligodactyly (hands) (HP:0001180)3.05939111
25True hermaphroditism (HP:0010459)3.04293789
26Generalized tonic-clonic seizures (HP:0002069)2.98586812
27Pancreatic cysts (HP:0001737)2.89330989
28Nephrogenic diabetes insipidus (HP:0009806)2.82226343
29Protruding tongue (HP:0010808)2.80962024
30Occipital encephalocele (HP:0002085)2.79807249
31Truncal ataxia (HP:0002078)2.69515044
32Progressive inability to walk (HP:0002505)2.69203454
33Chronic bronchitis (HP:0004469)2.68143834
34Absent speech (HP:0001344)2.68024538
35Limb dystonia (HP:0002451)2.68016971
36Cystic liver disease (HP:0006706)2.59984618
37Gaze-evoked nystagmus (HP:0000640)2.56187216
38Chronic hepatic failure (HP:0100626)2.55760535
39Action tremor (HP:0002345)2.48581899
40Mutism (HP:0002300)2.45371252
41Supranuclear gaze palsy (HP:0000605)2.44630132
42Dysdiadochokinesis (HP:0002075)2.44351444
43Amyotrophic lateral sclerosis (HP:0007354)2.42114672
44Amblyopia (HP:0000646)2.41194515
45Impaired vibration sensation in the lower limbs (HP:0002166)2.40337370
46Abnormality of the labia minora (HP:0012880)2.40020505
47Bronchiectasis (HP:0002110)2.39945761
48Abnormality of the corticospinal tract (HP:0002492)2.38750850
49Insidious onset (HP:0003587)2.34757432
50Termporal pattern (HP:0011008)2.34757432
51Rimmed vacuoles (HP:0003805)2.34420589
52Poor coordination (HP:0002370)2.33030228
53Hemiparesis (HP:0001269)2.32103688
54Dysmetria (HP:0001310)2.29741760
55Poor eye contact (HP:0000817)2.28813558
56Abnormality of the renal cortex (HP:0011035)2.27769848
57Papilledema (HP:0001085)2.25453964
58Preaxial hand polydactyly (HP:0001177)2.25244545
59Absent/shortened dynein arms (HP:0200106)2.24251096
60Dynein arm defect of respiratory motile cilia (HP:0012255)2.24251096
61Abnormality of salivation (HP:0100755)2.24213517
62Postaxial foot polydactyly (HP:0001830)2.23555443
63Horizontal nystagmus (HP:0000666)2.20994882
64Inappropriate behavior (HP:0000719)2.20941579
65Gonadotropin excess (HP:0000837)2.19715635
66Gait imbalance (HP:0002141)2.19162989
67Scanning speech (HP:0002168)2.17823739
68Ankle clonus (HP:0011448)2.15570516
69Urinary bladder sphincter dysfunction (HP:0002839)2.15488704
70Intestinal atresia (HP:0011100)2.15438395
71Inability to walk (HP:0002540)2.14591909
72Urinary urgency (HP:0000012)2.13292687
73Epileptiform EEG discharges (HP:0011182)2.13135286
74Impaired smooth pursuit (HP:0007772)2.11733363
75Colon cancer (HP:0003003)2.11167494
76Polyphagia (HP:0002591)2.09949895
77Abnormal hair whorl (HP:0010721)2.09424051
78Abnormal eating behavior (HP:0100738)2.08644585
79Exotropia (HP:0000577)2.08375219
80Postaxial hand polydactyly (HP:0001162)2.08209346
81Tubular atrophy (HP:0000092)2.06707109
82Widely spaced teeth (HP:0000687)2.06514755
83Diplopia (HP:0000651)2.05851108
84Abnormality of binocular vision (HP:0011514)2.05851108
85Hyperinsulinemic hypoglycemia (HP:0000825)2.04375088
86EEG with generalized epileptiform discharges (HP:0011198)2.03940047
87Cerebral inclusion bodies (HP:0100314)2.03858004
88Aplasia/Hypoplasia of the tongue (HP:0010295)2.03109313
89Spastic gait (HP:0002064)2.02750914
90Genetic anticipation (HP:0003743)2.02059508
91Degeneration of the lateral corticospinal tracts (HP:0002314)2.02058665
92Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.02058665
93Optic nerve hypoplasia (HP:0000609)2.01967233
94Anencephaly (HP:0002323)2.01499477
95Impaired social interactions (HP:0000735)2.00823524
96Abnormal social behavior (HP:0012433)2.00823524
97Anxiety (HP:0000739)1.98456975
98Depression (HP:0000716)1.97706596
99Gastroesophageal reflux (HP:0002020)1.96600142
100Specific learning disability (HP:0001328)1.95311062
101Supernumerary spleens (HP:0009799)1.94904700
102Neurofibrillary tangles (HP:0002185)1.94454164
103Oligodactyly (HP:0012165)1.92560522
104Narrow nasal bridge (HP:0000446)1.92215426
105Hypsarrhythmia (HP:0002521)1.90922984
106Tubulointerstitial abnormality (HP:0001969)1.90812498
107Abnormality of ocular smooth pursuit (HP:0000617)1.90702815
108Congenital hepatic fibrosis (HP:0002612)1.90652136
109Fetal akinesia sequence (HP:0001989)1.90216434
110Stereotypic behavior (HP:0000733)1.90153062
111Type II lissencephaly (HP:0007260)1.89296522
112Abdominal situs inversus (HP:0003363)1.88901518
113Abnormality of abdominal situs (HP:0011620)1.88901518
114Abnormal protein glycosylation (HP:0012346)1.88360268
115Abnormal glycosylation (HP:0012345)1.88360268
116Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.88360268
117Abnormal protein N-linked glycosylation (HP:0012347)1.88360268
118Sclerocornea (HP:0000647)1.87873508
119Fair hair (HP:0002286)1.87285282
120Blue irides (HP:0000635)1.86633842
121Type I transferrin isoform profile (HP:0003642)1.86207238
122Abnormal ciliary motility (HP:0012262)1.84638917
123Thickened helices (HP:0000391)1.81820126
124Narrow forehead (HP:0000341)1.81263681
125Atrophy/Degeneration involving motor neurons (HP:0007373)1.80557217
126Lower limb muscle weakness (HP:0007340)1.79962881
127Oculomotor apraxia (HP:0000657)1.79361187
128Agitation (HP:0000713)1.78879119
129Multicystic kidney dysplasia (HP:0000003)1.77682786
130Medial flaring of the eyebrow (HP:0010747)1.76909823
131Esotropia (HP:0000565)1.76160581
132Congenital primary aphakia (HP:0007707)1.75475260
133Megalencephaly (HP:0001355)1.74406026
134Genital tract atresia (HP:0001827)1.74045141
135Shoulder girdle muscle weakness (HP:0003547)1.72931873
136Labial hypoplasia (HP:0000066)1.72902131
137Prominent nasal bridge (HP:0000426)1.72817993
138Generalized hypopigmentation of hair (HP:0011358)1.72170985
139Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.71523157
140Aqueductal stenosis (HP:0002410)1.70540382
141Hypothermia (HP:0002045)1.67145726
142Male pseudohermaphroditism (HP:0000037)1.66891565
143Hepatoblastoma (HP:0002884)1.66819650
144Retinal dysplasia (HP:0007973)1.66485019
145Broad foot (HP:0001769)1.66413180
146Vaginal atresia (HP:0000148)1.66243880
147Highly arched eyebrow (HP:0002553)1.65398146
148Median cleft lip (HP:0000161)1.65037971
149Truncal obesity (HP:0001956)1.64880717
150Autism (HP:0000717)1.64422240
151Abnormality of midbrain morphology (HP:0002418)1.62811302
152Molar tooth sign on MRI (HP:0002419)1.62811302
153Postural instability (HP:0002172)1.62317134
154Abnormality of the lower motor neuron (HP:0002366)1.62211388
155Abnormal respiratory motile cilium physiology (HP:0012261)1.61987033
156Hyperthyroidism (HP:0000836)1.61342871
157Gait ataxia (HP:0002066)1.59152411
158Clumsiness (HP:0002312)1.57037686
159Sporadic (HP:0003745)1.55848219
160Pointed chin (HP:0000307)1.54400208

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.34285858
2MARK14.13308810
3FRK3.47119680
4EPHA43.42835667
5CASK3.29747795
6MAP3K43.24706779
7MAP3K93.01196313
8MAP2K72.88603922
9PNCK2.58879212
10TNIK2.46568263
11NTRK22.43773535
12MINK12.43690522
13MET2.43445152
14MAPK132.19493267
15KSR11.93451091
16PAK61.81066174
17PLK21.75646311
18MAP3K121.71110827
19MAP2K41.69362212
20MAP4K21.56355275
21TRIM281.48128827
22PINK11.44710551
23UHMK11.42464185
24KSR21.37092962
25CDK51.35968370
26STK38L1.35490806
27NTRK11.29732464
28SIK21.25247100
29PRKCG1.11956205
30ACVR1B1.08994869
31CSNK1G21.08353324
32FES1.06190372
33CAMK2A1.05737067
34BMX1.05575970
35TYRO31.04506620
36DYRK1A1.01346925
37BCR1.01196653
38DAPK21.00067128
39PAK30.99998377
40MAPK150.99271465
41WNK30.97628446
42NUAK10.96545934
43CDK190.96405708
44LATS20.94557369
45PHKG20.94109108
46PHKG10.94109108
47CDK180.90208740
48PRPF4B0.87887339
49FGR0.87251657
50RIPK40.86714904
51CDK140.86692084
52CDK150.86449040
53GRK50.86014468
54WEE10.83083456
55OXSR10.82837035
56RAF10.82709220
57MAP3K130.80649529
58CAMK2B0.80380594
59PLK40.78678945
60MKNK20.78090280
61SGK10.78019876
62MST40.77320988
63CAMKK10.76819878
64STK110.76808681
65PLK10.76359182
66GRK10.76349408
67DAPK10.75667239
68STK390.75569824
69TSSK60.74462370
70CDK11A0.74452237
71PKN10.74133201
72WNK10.74112776
73ARAF0.73399701
74ERBB30.73040871
75PASK0.72277051
76SGK4940.72197618
77SGK2230.72197618
78PRKD30.72058951
79CSNK1G30.72017424
80TTK0.72014475
81DYRK30.70740428
82INSRR0.67744604
83CAMK1G0.66921151
84BMPR1B0.65524698
85FGFR20.64158472
86NME10.62960405
87ZAK0.62688491
88MAP3K60.62078308
89DYRK20.61890536
90RET0.61132674
91SGK20.60933113
92PRKCE0.59525100
93PTK2B0.59054945
94ADRBK20.58623338
95MUSK0.58036488
96ROCK20.56375503
97OBSCN0.56273283
98MARK20.55680288
99CSF1R0.55267429
100PRKCI0.54266861
101STK380.54209492
102ATM0.54154601
103CSNK1A1L0.53978462
104CAMK10.53527061
105MAPK100.51253112
106RPS6KB10.50907507
107NEK60.50768260
108PLK30.49380600
109LATS10.49032002
110YES10.48155436
111STK160.47884032
112EGFR0.47760911
113NEK10.46578553
114CDK30.46290682
115CAMKK20.45986686
116RPS6KA30.45940305
117ATR0.45903959
118NLK0.45629163
119PDGFRB0.45020975
120CSNK1G10.44342048
121ADRBK10.44066285
122STK30.43784295
123CDC42BPA0.42942055
124CSNK1E0.42671493
125CAMK2D0.42457398
126PRKG10.42390006
127PRKCH0.42380627
128MAP3K20.42163823
129GRK70.41382765
130FYN0.41150323
131DMPK0.40939095
132CCNB10.40533178
133BMPR20.40520104
134BRD40.40389897
135MKNK10.40278970
136PRKAA10.39740465
137WNK40.39113476
138PRKCZ0.38425978
139SRPK10.37877335
140AKT30.37195489
141EPHA30.35890911
142NEK20.33665322
143CSNK1D0.33629867

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.38180704
2Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.87570585
3GABAergic synapse_Homo sapiens_hsa047272.80508853
4Synaptic vesicle cycle_Homo sapiens_hsa047212.61251018
5Morphine addiction_Homo sapiens_hsa050322.57742093
6Glutamatergic synapse_Homo sapiens_hsa047242.57612251
7Circadian entrainment_Homo sapiens_hsa047132.54954083
8Long-term potentiation_Homo sapiens_hsa047202.49148583
9Maturity onset diabetes of the young_Homo sapiens_hsa049502.46019833
10Amphetamine addiction_Homo sapiens_hsa050312.35018549
11Olfactory transduction_Homo sapiens_hsa047402.24120249
12Dopaminergic synapse_Homo sapiens_hsa047282.19163636
13Protein export_Homo sapiens_hsa030602.18114605
14Butanoate metabolism_Homo sapiens_hsa006502.10464819
15Taste transduction_Homo sapiens_hsa047422.06275161
16Serotonergic synapse_Homo sapiens_hsa047262.03267746
17Salivary secretion_Homo sapiens_hsa049701.98529889
18Long-term depression_Homo sapiens_hsa047301.97588657
19Fanconi anemia pathway_Homo sapiens_hsa034601.84558922
20Propanoate metabolism_Homo sapiens_hsa006401.83026123
21Insulin secretion_Homo sapiens_hsa049111.80282662
22Cholinergic synapse_Homo sapiens_hsa047251.79499664
23Cocaine addiction_Homo sapiens_hsa050301.78606109
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.72224277
25Renin secretion_Homo sapiens_hsa049241.70874898
26Axon guidance_Homo sapiens_hsa043601.65783191
27Regulation of autophagy_Homo sapiens_hsa041401.65212918
28Gastric acid secretion_Homo sapiens_hsa049711.58660277
29Oxytocin signaling pathway_Homo sapiens_hsa049211.57661459
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.57278661
31Calcium signaling pathway_Homo sapiens_hsa040201.55232834
32Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51679526
33Non-homologous end-joining_Homo sapiens_hsa034501.50994752
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.50646090
35Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.50325801
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.49951540
37beta-Alanine metabolism_Homo sapiens_hsa004101.42534307
38Gap junction_Homo sapiens_hsa045401.38804936
39Homologous recombination_Homo sapiens_hsa034401.34851880
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.33561053
41GnRH signaling pathway_Homo sapiens_hsa049121.33119428
42RNA degradation_Homo sapiens_hsa030181.26146057
43Basal transcription factors_Homo sapiens_hsa030221.24282528
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.23975996
45Oocyte meiosis_Homo sapiens_hsa041141.20998142
46cAMP signaling pathway_Homo sapiens_hsa040241.20847150
47Steroid biosynthesis_Homo sapiens_hsa001001.19416013
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18274097
49Collecting duct acid secretion_Homo sapiens_hsa049661.17313695
50Melanogenesis_Homo sapiens_hsa049161.16501460
51Phototransduction_Homo sapiens_hsa047441.15963936
52Cardiac muscle contraction_Homo sapiens_hsa042601.13991432
53Estrogen signaling pathway_Homo sapiens_hsa049151.13879930
54Selenocompound metabolism_Homo sapiens_hsa004501.12010048
55ErbB signaling pathway_Homo sapiens_hsa040121.07150999
56Alcoholism_Homo sapiens_hsa050341.01949713
57Linoleic acid metabolism_Homo sapiens_hsa005911.01584103
58cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00773565
59Fatty acid metabolism_Homo sapiens_hsa012120.97693130
60Type II diabetes mellitus_Homo sapiens_hsa049300.97177436
61Glioma_Homo sapiens_hsa052140.95891249
62Peroxisome_Homo sapiens_hsa041460.95415289
63Vascular smooth muscle contraction_Homo sapiens_hsa042700.95285287
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.94770314
65Phosphatidylinositol signaling system_Homo sapiens_hsa040700.94310665
66Fatty acid elongation_Homo sapiens_hsa000620.94283201
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91912577
68Tryptophan metabolism_Homo sapiens_hsa003800.89692971
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88826545
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88729718
71Dorso-ventral axis formation_Homo sapiens_hsa043200.88043482
72RNA transport_Homo sapiens_hsa030130.87048607
73Mismatch repair_Homo sapiens_hsa034300.85341925
74Wnt signaling pathway_Homo sapiens_hsa043100.81649305
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.80412244
76ABC transporters_Homo sapiens_hsa020100.78991465
77Dilated cardiomyopathy_Homo sapiens_hsa054140.78976666
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78841421
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77576095
80MAPK signaling pathway_Homo sapiens_hsa040100.77327489
81Fatty acid degradation_Homo sapiens_hsa000710.77256355
82Vibrio cholerae infection_Homo sapiens_hsa051100.77029912
83Choline metabolism in cancer_Homo sapiens_hsa052310.76984860
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74999671
85N-Glycan biosynthesis_Homo sapiens_hsa005100.74722264
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74272767
87Lysine degradation_Homo sapiens_hsa003100.74121093
88Retinol metabolism_Homo sapiens_hsa008300.71786202
89Thyroid hormone synthesis_Homo sapiens_hsa049180.71315217
90Pancreatic secretion_Homo sapiens_hsa049720.69688679
91Alzheimers disease_Homo sapiens_hsa050100.68024904
92Ras signaling pathway_Homo sapiens_hsa040140.67883207
93Histidine metabolism_Homo sapiens_hsa003400.67128750
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66558767
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64253176
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64068537
97Colorectal cancer_Homo sapiens_hsa052100.63824787
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.63707136
99Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63538932
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61449245
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60097730
102Renal cell carcinoma_Homo sapiens_hsa052110.58295401
103Hedgehog signaling pathway_Homo sapiens_hsa043400.58209929
104Rap1 signaling pathway_Homo sapiens_hsa040150.56727187
105Nucleotide excision repair_Homo sapiens_hsa034200.56136183
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55898886
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.54784861
108Cell cycle_Homo sapiens_hsa041100.54141396
109Tight junction_Homo sapiens_hsa045300.53345665
110Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53312376
111Chemical carcinogenesis_Homo sapiens_hsa052040.52937626
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.52505021
113Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.52432938
114Oxidative phosphorylation_Homo sapiens_hsa001900.51934790
115Phenylalanine metabolism_Homo sapiens_hsa003600.51864222
116Primary bile acid biosynthesis_Homo sapiens_hsa001200.51780275
117Circadian rhythm_Homo sapiens_hsa047100.50422319
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49499934
119Caffeine metabolism_Homo sapiens_hsa002320.49276463
120Endometrial cancer_Homo sapiens_hsa052130.49101426
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48939458
122Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.47393269
123Glucagon signaling pathway_Homo sapiens_hsa049220.46598484
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45959421
125Type I diabetes mellitus_Homo sapiens_hsa049400.45810356
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.45044531
127Huntingtons disease_Homo sapiens_hsa050160.44082742
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43392486
129Parkinsons disease_Homo sapiens_hsa050120.42529673
130Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42089978
131Ovarian steroidogenesis_Homo sapiens_hsa049130.41469630
132Inositol phosphate metabolism_Homo sapiens_hsa005620.40502551
133VEGF signaling pathway_Homo sapiens_hsa043700.39273769
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39110633
135Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38101651
136mTOR signaling pathway_Homo sapiens_hsa041500.37994611
137Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.37376186
138Ether lipid metabolism_Homo sapiens_hsa005650.37332277
139mRNA surveillance pathway_Homo sapiens_hsa030150.37328163
140Melanoma_Homo sapiens_hsa052180.37107818
141Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36809419
142Basal cell carcinoma_Homo sapiens_hsa052170.36754700
143Hippo signaling pathway_Homo sapiens_hsa043900.34760197
144Non-small cell lung cancer_Homo sapiens_hsa052230.34410171

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