Rank | Gene Set | Z-score |
---|---|---|
1 | maturation of SSU-rRNA (GO:0030490) | 5.27485542 |
2 | ribosomal small subunit assembly (GO:0000028) | 5.01727529 |
3 | ribosomal small subunit biogenesis (GO:0042274) | 4.81029347 |
4 | ribosomal large subunit biogenesis (GO:0042273) | 4.71819986 |
5 | viral transcription (GO:0019083) | 4.71613307 |
6 | translational termination (GO:0006415) | 4.65664372 |
7 | nucleobase biosynthetic process (GO:0046112) | 4.59863287 |
8 | formation of translation preinitiation complex (GO:0001731) | 4.58161151 |
9 | * ribonucleoprotein complex biogenesis (GO:0022613) | 4.44078771 |
10 | purine nucleobase biosynthetic process (GO:0009113) | 4.39210981 |
11 | regulation of mitochondrial translation (GO:0070129) | 4.38499918 |
12 | ribosome assembly (GO:0042255) | 4.37795586 |
13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.28045390 |
14 | * ribosome biogenesis (GO:0042254) | 4.27023593 |
15 | DNA deamination (GO:0045006) | 4.26634874 |
16 | chaperone-mediated protein transport (GO:0072321) | 4.25613180 |
17 | mitotic metaphase plate congression (GO:0007080) | 4.25582990 |
18 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.24278685 |
19 | DNA replication initiation (GO:0006270) | 4.22370892 |
20 | translational elongation (GO:0006414) | 4.21330411 |
21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.20450096 |
22 | translational initiation (GO:0006413) | 4.19145791 |
23 | DNA replication checkpoint (GO:0000076) | 4.09427231 |
24 | rRNA processing (GO:0006364) | 4.07603991 |
25 | DNA strand elongation (GO:0022616) | 4.04385625 |
26 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.95649814 |
27 | rRNA metabolic process (GO:0016072) | 3.94706342 |
28 | spliceosomal snRNP assembly (GO:0000387) | 3.94490093 |
29 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.92997881 |
30 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.91467876 |
31 | protein localization to kinetochore (GO:0034501) | 3.91321074 |
32 | proteasome assembly (GO:0043248) | 3.90440418 |
33 | IMP biosynthetic process (GO:0006188) | 3.82354885 |
34 | cotranslational protein targeting to membrane (GO:0006613) | 3.81951148 |
35 | rRNA modification (GO:0000154) | 3.81281317 |
36 | CENP-A containing nucleosome assembly (GO:0034080) | 3.81059639 |
37 | protein targeting to ER (GO:0045047) | 3.80773549 |
38 | protein targeting to mitochondrion (GO:0006626) | 3.77561652 |
39 | chromatin remodeling at centromere (GO:0031055) | 3.75868488 |
40 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.74353864 |
41 | DNA unwinding involved in DNA replication (GO:0006268) | 3.74012412 |
42 | cellular protein complex disassembly (GO:0043624) | 3.72091124 |
43 | establishment of viral latency (GO:0019043) | 3.67147008 |
44 | metaphase plate congression (GO:0051310) | 3.65581861 |
45 | pseudouridine synthesis (GO:0001522) | 3.65578899 |
46 | regulation of translational fidelity (GO:0006450) | 3.64494553 |
47 | viral life cycle (GO:0019058) | 3.62835819 |
48 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.62269465 |
49 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.62269465 |
50 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.61891172 |
51 | mitotic nuclear envelope disassembly (GO:0007077) | 3.59628904 |
52 | telomere maintenance via recombination (GO:0000722) | 3.59098323 |
53 | ATP synthesis coupled proton transport (GO:0015986) | 3.58318220 |
54 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.58318220 |
55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.57517866 |
56 | termination of RNA polymerase III transcription (GO:0006386) | 3.57517866 |
57 | protein localization to endoplasmic reticulum (GO:0070972) | 3.56812158 |
58 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.56534971 |
59 | DNA replication-independent nucleosome organization (GO:0034724) | 3.50412056 |
60 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.50412056 |
61 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.49732458 |
62 | regulation of translational termination (GO:0006449) | 3.49171175 |
63 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.49083375 |
64 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.47709014 |
65 | termination of RNA polymerase I transcription (GO:0006363) | 3.46676277 |
66 | protein localization to mitochondrion (GO:0070585) | 3.45167769 |
67 | kinetochore organization (GO:0051383) | 3.45145191 |
68 | spliceosomal complex assembly (GO:0000245) | 3.45101850 |
69 | establishment of protein localization to mitochondrion (GO:0072655) | 3.44905889 |
70 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.43419864 |
71 | translation (GO:0006412) | 3.42657864 |
72 | nuclear pore organization (GO:0006999) | 3.42218670 |
73 | mitotic recombination (GO:0006312) | 3.40678551 |
74 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.39505302 |
75 | tRNA aminoacylation for protein translation (GO:0006418) | 3.39456673 |
76 | regulation of spindle organization (GO:0090224) | 3.39408027 |
77 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.39172250 |
78 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.37960456 |
79 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.36695012 |
80 | tRNA aminoacylation (GO:0043039) | 3.34735759 |
81 | amino acid activation (GO:0043038) | 3.34735759 |
82 | telomere maintenance via telomere lengthening (GO:0010833) | 3.34652267 |
83 | * cellular component biogenesis (GO:0044085) | 3.34073319 |
84 | protein localization to chromosome, centromeric region (GO:0071459) | 3.33984877 |
85 | protein complex disassembly (GO:0043241) | 3.32898870 |
86 | maturation of 5.8S rRNA (GO:0000460) | 3.32689318 |
87 | kinetochore assembly (GO:0051382) | 3.32449270 |
88 | membrane disassembly (GO:0030397) | 3.31270668 |
89 | nuclear envelope disassembly (GO:0051081) | 3.31270668 |
90 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.30916754 |
91 | IMP metabolic process (GO:0046040) | 3.30483772 |
92 | transcription from RNA polymerase I promoter (GO:0006360) | 3.28738898 |
93 | 7-methylguanosine mRNA capping (GO:0006370) | 3.27550850 |
94 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.26684653 |
95 | establishment of integrated proviral latency (GO:0075713) | 3.25862157 |
96 | positive regulation of ligase activity (GO:0051351) | 3.25832518 |
97 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.25717085 |
98 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.25717085 |
99 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.25532039 |
100 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.25532039 |
101 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.25532039 |
102 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.25185751 |
103 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.25185751 |
104 | histone exchange (GO:0043486) | 3.22076130 |
105 | RNA capping (GO:0036260) | 3.21786344 |
106 | 7-methylguanosine RNA capping (GO:0009452) | 3.21786344 |
107 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.20214978 |
108 | negative regulation of ligase activity (GO:0051352) | 3.20214978 |
109 | transcription from mitochondrial promoter (GO:0006390) | 3.18862915 |
110 | mitochondrial RNA metabolic process (GO:0000959) | 3.18052078 |
111 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.18030862 |
112 | protein maturation by protein folding (GO:0022417) | 3.17715356 |
113 | macromolecular complex disassembly (GO:0032984) | 3.17524858 |
114 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.16668668 |
115 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.15818910 |
116 | respiratory electron transport chain (GO:0022904) | 3.14432321 |
117 | establishment of chromosome localization (GO:0051303) | 3.14133571 |
118 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.11488855 |
119 | viral mRNA export from host cell nucleus (GO:0046784) | 3.10324394 |
120 | nuclear pore complex assembly (GO:0051292) | 3.10246793 |
121 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.09824535 |
122 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.09091562 |
123 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.07939235 |
124 | folic acid metabolic process (GO:0046655) | 3.07477364 |
125 | ncRNA processing (GO:0034470) | 3.06795377 |
126 | electron transport chain (GO:0022900) | 3.06751225 |
127 | regulation of ligase activity (GO:0051340) | 3.06107545 |
128 | cell cycle G1/S phase transition (GO:0044843) | 3.05435089 |
129 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.05435089 |
130 | DNA damage response, detection of DNA damage (GO:0042769) | 3.02283850 |
131 | mitotic chromosome condensation (GO:0007076) | 3.01932114 |
132 | rRNA methylation (GO:0031167) | 3.01533627 |
133 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.01436228 |
134 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.00972837 |
135 | tRNA methylation (GO:0030488) | 3.00299774 |
136 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.00076129 |
137 | RNA splicing, via transesterification reactions (GO:0000375) | 2.99608730 |
138 | mRNA catabolic process (GO:0006402) | 2.99553388 |
139 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.99358963 |
140 | mitotic sister chromatid segregation (GO:0000070) | 2.99306109 |
141 | DNA-templated transcription, termination (GO:0006353) | 2.99197118 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.61615116 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.81999794 |
3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.75447769 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.59173848 |
5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.48713722 |
6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.44834360 |
7 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.42464282 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.36006286 |
9 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.25615507 |
10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.22154274 |
11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.16796599 |
12 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 3.08320851 |
13 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.07347295 |
14 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.98790544 |
15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.98312116 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.65472283 |
17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.53042267 |
18 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.52457396 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.46669734 |
20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.44284339 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.42527438 |
22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.41708046 |
23 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.16660387 |
24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.15864209 |
25 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.14282235 |
26 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.12814646 |
27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.12431405 |
28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.08438469 |
29 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.06067110 |
30 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.04415354 |
31 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.99730708 |
32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.95718166 |
33 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.95586682 |
34 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.92173847 |
35 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.91029074 |
36 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.89526138 |
37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.89466858 |
38 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88773863 |
39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.87339040 |
40 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.81244161 |
41 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.77929032 |
42 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.73533607 |
43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.73447638 |
44 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.70398579 |
45 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.69441615 |
46 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.61482933 |
47 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.60510985 |
48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.60224922 |
49 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.49567839 |
50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.48443388 |
51 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47716217 |
52 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.45045617 |
53 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.44206116 |
54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42628658 |
55 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.41680308 |
56 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.37747156 |
57 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.37259057 |
58 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.33702009 |
59 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.32241953 |
60 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.31874635 |
61 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.31453159 |
62 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.28876738 |
63 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.24450900 |
64 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.22883084 |
65 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.22054947 |
66 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.20681934 |
67 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.18691539 |
68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.18647852 |
69 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17915441 |
70 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.15901460 |
71 | MYC_22102868_ChIP-Seq_BL_Human | 1.15383731 |
72 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14983855 |
73 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.13909221 |
74 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.13337189 |
75 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.12492835 |
76 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.12402314 |
77 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.11763026 |
78 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.07651027 |
79 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06720802 |
80 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05848446 |
81 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.04440988 |
82 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.03889936 |
83 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.03596797 |
84 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.01622300 |
85 | * SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.00186309 |
86 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.98818368 |
87 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.98683999 |
88 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.97837956 |
89 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.97007058 |
90 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.97007058 |
91 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.97007058 |
92 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.95474811 |
93 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.95279483 |
94 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.95068079 |
95 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.95018125 |
96 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.94882181 |
97 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.94843256 |
98 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.93278239 |
99 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.92333874 |
100 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.91268232 |
101 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.90331127 |
102 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.89417313 |
103 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.89285486 |
104 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.88766645 |
105 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.86707133 |
106 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.86334135 |
107 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.86280065 |
108 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.85385594 |
109 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.84209539 |
110 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.84058543 |
111 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83665068 |
112 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.82660706 |
113 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.82530962 |
114 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.81747290 |
115 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.80513570 |
116 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.80177634 |
117 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.79783992 |
118 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.77759281 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 6.01002234 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.87262469 |
3 | MP0003111_abnormal_nucleus_morphology | 4.69639145 |
4 | MP0010094_abnormal_chromosome_stability | 4.61969998 |
5 | MP0003077_abnormal_cell_cycle | 4.18528417 |
6 | MP0008057_abnormal_DNA_replication | 3.88920628 |
7 | MP0008058_abnormal_DNA_repair | 3.73365056 |
8 | MP0008007_abnormal_cellular_replicative | 3.10196079 |
9 | MP0008932_abnormal_embryonic_tissue | 2.99256199 |
10 | MP0002877_abnormal_melanocyte_morpholog | 2.52774075 |
11 | MP0009697_abnormal_copulation | 2.49575482 |
12 | MP0001730_embryonic_growth_arrest | 2.42604497 |
13 | MP0003786_premature_aging | 2.39967637 |
14 | MP0003123_paternal_imprinting | 2.33272478 |
15 | MP0000350_abnormal_cell_proliferation | 2.30859061 |
16 | MP0003718_maternal_effect | 2.23751039 |
17 | MP0008877_abnormal_DNA_methylation | 2.14587999 |
18 | MP0002396_abnormal_hematopoietic_system | 2.05551573 |
19 | MP0001672_abnormal_embryogenesis/_devel | 1.74538385 |
20 | MP0005380_embryogenesis_phenotype | 1.74538385 |
21 | MP0001697_abnormal_embryo_size | 1.72451625 |
22 | MP0002080_prenatal_lethality | 1.63564931 |
23 | MP0010352_gastrointestinal_tract_polyps | 1.61848049 |
24 | MP0010030_abnormal_orbit_morphology | 1.60908695 |
25 | MP0003806_abnormal_nucleotide_metabolis | 1.58005645 |
26 | MP0010307_abnormal_tumor_latency | 1.57732206 |
27 | MP0002085_abnormal_embryonic_tissue | 1.57088118 |
28 | MP0009379_abnormal_foot_pigmentation | 1.56046541 |
29 | MP0006292_abnormal_olfactory_placode | 1.52222461 |
30 | MP0003941_abnormal_skin_development | 1.51777478 |
31 | MP0003984_embryonic_growth_retardation | 1.50789110 |
32 | MP0000490_abnormal_crypts_of | 1.49984647 |
33 | MP0000313_abnormal_cell_death | 1.47369170 |
34 | MP0002088_abnormal_embryonic_growth/wei | 1.46585543 |
35 | MP0009333_abnormal_splenocyte_physiolog | 1.43250128 |
36 | MP0002084_abnormal_developmental_patter | 1.42284551 |
37 | MP0003950_abnormal_plasma_membrane | 1.37587753 |
38 | MP0002234_abnormal_pharynx_morphology | 1.35317525 |
39 | MP0004197_abnormal_fetal_growth/weight/ | 1.34797798 |
40 | MP0003315_abnormal_perineum_morphology | 1.33212881 |
41 | MP0005623_abnormal_meninges_morphology | 1.32750605 |
42 | MP0002019_abnormal_tumor_incidence | 1.32599360 |
43 | MP0001293_anophthalmia | 1.29065449 |
44 | MP0002086_abnormal_extraembryonic_tissu | 1.28989955 |
45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.24669817 |
46 | MP0001529_abnormal_vocalization | 1.24135105 |
47 | MP0002210_abnormal_sex_determination | 1.23795275 |
48 | MP0004233_abnormal_muscle_weight | 1.19678669 |
49 | MP0003890_abnormal_embryonic-extraembry | 1.18915637 |
50 | MP0004808_abnormal_hematopoietic_stem | 1.18474932 |
51 | MP0001881_abnormal_mammary_gland | 1.17295868 |
52 | MP0002132_abnormal_respiratory_system | 1.16615177 |
53 | MP0001661_extended_life_span | 1.15677726 |
54 | MP0000678_abnormal_parathyroid_gland | 1.14156652 |
55 | MP0001145_abnormal_male_reproductive | 1.10822274 |
56 | MP0003121_genomic_imprinting | 1.08687587 |
57 | MP0004133_heterotaxia | 1.08437683 |
58 | MP0002160_abnormal_reproductive_system | 1.06725169 |
59 | MP0002796_impaired_skin_barrier | 1.06038737 |
60 | MP0003763_abnormal_thymus_physiology | 1.02851144 |
61 | MP0003186_abnormal_redox_activity | 1.00330240 |
62 | MP0000703_abnormal_thymus_morphology | 1.00284829 |
63 | MP0000537_abnormal_urethra_morphology | 0.97666152 |
64 | MP0000358_abnormal_cell_content/ | 0.97639902 |
65 | MP0000762_abnormal_tongue_morphology | 0.92953363 |
66 | MP0005408_hypopigmentation | 0.92212078 |
67 | MP0000653_abnormal_sex_gland | 0.92132877 |
68 | MP0005330_cardiomyopathy | 0.90706581 |
69 | MP0003119_abnormal_digestive_system | 0.90369052 |
70 | MP0002653_abnormal_ependyma_morphology | 0.89333481 |
71 | MP0001929_abnormal_gametogenesis | 0.88106377 |
72 | MP0005389_reproductive_system_phenotype | 0.88027689 |
73 | MP0002102_abnormal_ear_morphology | 0.86400024 |
74 | MP0000750_abnormal_muscle_regeneration | 0.84884128 |
75 | MP0000579_abnormal_nail_morphology | 0.84656928 |
76 | MP0002938_white_spotting | 0.83812401 |
77 | MP0002722_abnormal_immune_system | 0.82983853 |
78 | MP0002111_abnormal_tail_morphology | 0.82831184 |
79 | MP0005397_hematopoietic_system_phenotyp | 0.82377611 |
80 | MP0001545_abnormal_hematopoietic_system | 0.82377611 |
81 | MP0002398_abnormal_bone_marrow | 0.80929910 |
82 | MP0000858_altered_metastatic_potential | 0.80883081 |
83 | MP0008789_abnormal_olfactory_epithelium | 0.80240215 |
84 | MP0005384_cellular_phenotype | 0.78375511 |
85 | MP0002177_abnormal_outer_ear | 0.78212328 |
86 | MP0003937_abnormal_limbs/digits/tail_de | 0.77590217 |
87 | MP0001286_abnormal_eye_development | 0.77300188 |
88 | MP0002060_abnormal_skin_morphology | 0.77190484 |
89 | MP0005076_abnormal_cell_differentiation | 0.76005532 |
90 | MP0006035_abnormal_mitochondrial_morpho | 0.75690873 |
91 | MP0000627_abnormal_mammary_gland | 0.75206730 |
92 | MP0001119_abnormal_female_reproductive | 0.75151663 |
93 | MP0000689_abnormal_spleen_morphology | 0.73235889 |
94 | MP0003136_yellow_coat_color | 0.73193771 |
95 | MP0002269_muscular_atrophy | 0.71764579 |
96 | MP0005621_abnormal_cell_physiology | 0.71119439 |
97 | MP0003385_abnormal_body_wall | 0.70726767 |
98 | MP0002697_abnormal_eye_size | 0.70189741 |
99 | MP0009672_abnormal_birth_weight | 0.69965424 |
100 | MP0008875_abnormal_xenobiotic_pharmacok | 0.69073413 |
101 | MP0000647_abnormal_sebaceous_gland | 0.68282096 |
102 | MP0001919_abnormal_reproductive_system | 0.68101390 |
103 | MP0000428_abnormal_craniofacial_morphol | 0.66700162 |
104 | MP0000372_irregular_coat_pigmentation | 0.65156058 |
105 | MP0005257_abnormal_intraocular_pressure | 0.65134258 |
106 | MP0001853_heart_inflammation | 0.64056541 |
107 | MP0001764_abnormal_homeostasis | 0.63706294 |
108 | MP0002163_abnormal_gland_morphology | 0.63358625 |
109 | MP0005501_abnormal_skin_physiology | 0.62978094 |
110 | MP0002429_abnormal_blood_cell | 0.62521811 |
111 | MP0000049_abnormal_middle_ear | 0.62179893 |
112 | MP0010771_integument_phenotype | 0.62141076 |
113 | MP0005023_abnormal_wound_healing | 0.60952487 |
114 | MP0003221_abnormal_cardiomyocyte_apopto | 0.60874764 |
115 | MP0009053_abnormal_anal_canal | 0.60577383 |
116 | MP0005395_other_phenotype | 0.60513659 |
117 | MP0000467_abnormal_esophagus_morphology | 0.59605803 |
118 | MP0003938_abnormal_ear_development | 0.58993395 |
119 | MP0001727_abnormal_embryo_implantation | 0.58586183 |
120 | MP0004185_abnormal_adipocyte_glucose | 0.57598053 |
121 | MP0000432_abnormal_head_morphology | 0.57316110 |
122 | MP0000749_muscle_degeneration | 0.57113334 |
123 | MP0009703_decreased_birth_body | 0.56430550 |
124 | MP0002161_abnormal_fertility/fecundity | 0.56403069 |
125 | MP0002092_abnormal_eye_morphology | 0.55995003 |
126 | MP0008873_increased_physiological_sensi | 0.55758836 |
127 | MP0005410_abnormal_fertilization | 0.55586411 |
128 | MP0003936_abnormal_reproductive_system | 0.55505324 |
129 | MP0009250_abnormal_appendicular_skeleto | 0.54651588 |
130 | MP0005084_abnormal_gallbladder_morpholo | 0.53396537 |
131 | MP0008260_abnormal_autophagy | 0.52847027 |
132 | MP0001915_intracranial_hemorrhage | 0.51534422 |
133 | MP0001216_abnormal_epidermal_layer | 0.51381565 |
134 | MP0001243_abnormal_dermal_layer | 0.51326293 |
135 | MP0002114_abnormal_axial_skeleton | 0.50792420 |
136 | MP0002751_abnormal_autonomic_nervous | 0.50143686 |
137 | MP0006036_abnormal_mitochondrial_physio | 0.49113427 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.19138503 |
2 | Reticulocytopenia (HP:0001896) | 5.10565940 |
3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.07460671 |
4 | Acute necrotizing encephalopathy (HP:0006965) | 4.81750231 |
5 | Abnormal number of erythroid precursors (HP:0012131) | 4.73418303 |
6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.69531922 |
7 | Breast hypoplasia (HP:0003187) | 4.41120267 |
8 | Acute encephalopathy (HP:0006846) | 4.30329836 |
9 | Increased CSF lactate (HP:0002490) | 3.90636713 |
10 | Mitochondrial inheritance (HP:0001427) | 3.84622395 |
11 | Macrocytic anemia (HP:0001972) | 3.83672232 |
12 | Progressive macrocephaly (HP:0004481) | 3.75024022 |
13 | Carpal bone hypoplasia (HP:0001498) | 3.64011889 |
14 | Oral leukoplakia (HP:0002745) | 3.60758309 |
15 | Cerebral edema (HP:0002181) | 3.56674530 |
16 | Rough bone trabeculation (HP:0100670) | 3.53814287 |
17 | Cerebral hypomyelination (HP:0006808) | 3.50547259 |
18 | Increased hepatocellular lipid droplets (HP:0006565) | 3.46006161 |
19 | Chromsome breakage (HP:0040012) | 3.39995497 |
20 | Patellar aplasia (HP:0006443) | 3.39264185 |
21 | Pallor (HP:0000980) | 3.38285581 |
22 | Hepatocellular necrosis (HP:0001404) | 3.31631050 |
23 | Colon cancer (HP:0003003) | 3.29464763 |
24 | Aplasia/Hypoplasia of the patella (HP:0006498) | 3.22022238 |
25 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.20499586 |
26 | Degeneration of anterior horn cells (HP:0002398) | 3.19979800 |
27 | Abnormality of the anterior horn cell (HP:0006802) | 3.19979800 |
28 | Lipid accumulation in hepatocytes (HP:0006561) | 3.16693070 |
29 | Hepatic necrosis (HP:0002605) | 3.16149305 |
30 | Selective tooth agenesis (HP:0001592) | 3.06189623 |
31 | Trismus (HP:0000211) | 3.02395218 |
32 | Meckel diverticulum (HP:0002245) | 3.00988792 |
33 | Abnormality of the preputium (HP:0100587) | 2.99712829 |
34 | Absent radius (HP:0003974) | 2.97884096 |
35 | Lactic acidosis (HP:0003128) | 2.94772024 |
36 | Absent thumb (HP:0009777) | 2.94716069 |
37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.90133012 |
38 | Type I transferrin isoform profile (HP:0003642) | 2.88842728 |
39 | Exercise intolerance (HP:0003546) | 2.86892695 |
40 | Abnormality of the ileum (HP:0001549) | 2.83026878 |
41 | Aplastic anemia (HP:0001915) | 2.82282275 |
42 | Hyperalaninemia (HP:0003348) | 2.78049538 |
43 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.78049538 |
44 | Abnormality of alanine metabolism (HP:0010916) | 2.78049538 |
45 | Multiple enchondromatosis (HP:0005701) | 2.76729579 |
46 | Absent forearm bone (HP:0003953) | 2.76093181 |
47 | Aplasia involving forearm bones (HP:0009822) | 2.76093181 |
48 | Abnormality of the labia minora (HP:0012880) | 2.71077726 |
49 | Premature graying of hair (HP:0002216) | 2.70328597 |
50 | Abnormality of chromosome stability (HP:0003220) | 2.69159969 |
51 | Renal Fanconi syndrome (HP:0001994) | 2.66689234 |
52 | Impulsivity (HP:0100710) | 2.63494468 |
53 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.60789619 |
54 | Horseshoe kidney (HP:0000085) | 2.60038978 |
55 | Testicular atrophy (HP:0000029) | 2.60022955 |
56 | Abnormal trabecular bone morphology (HP:0100671) | 2.59456641 |
57 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.55841998 |
58 | Medulloblastoma (HP:0002885) | 2.52277461 |
59 | Reduced antithrombin III activity (HP:0001976) | 2.49477276 |
60 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.49115836 |
61 | Respiratory failure (HP:0002878) | 2.48878906 |
62 | Premature ovarian failure (HP:0008209) | 2.44628284 |
63 | Neoplasm of the pancreas (HP:0002894) | 2.43722338 |
64 | 11 pairs of ribs (HP:0000878) | 2.42426720 |
65 | Cleft eyelid (HP:0000625) | 2.42257248 |
66 | Myelodysplasia (HP:0002863) | 2.41544081 |
67 | Microretrognathia (HP:0000308) | 2.38675066 |
68 | Leukodystrophy (HP:0002415) | 2.37957045 |
69 | Ragged-red muscle fibers (HP:0003200) | 2.35958387 |
70 | Increased muscle lipid content (HP:0009058) | 2.35447879 |
71 | Triphalangeal thumb (HP:0001199) | 2.35231304 |
72 | Small intestinal stenosis (HP:0012848) | 2.35140485 |
73 | Duodenal stenosis (HP:0100867) | 2.35140485 |
74 | Abnormal protein glycosylation (HP:0012346) | 2.33861982 |
75 | Abnormal glycosylation (HP:0012345) | 2.33861982 |
76 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.33861982 |
77 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.33861982 |
78 | Glossoptosis (HP:0000162) | 2.33287531 |
79 | Bone marrow hypocellularity (HP:0005528) | 2.30915881 |
80 | Ependymoma (HP:0002888) | 2.30891953 |
81 | Atresia of the external auditory canal (HP:0000413) | 2.28419001 |
82 | Secondary amenorrhea (HP:0000869) | 2.26739710 |
83 | Abnormal number of incisors (HP:0011064) | 2.25326201 |
84 | Agnosia (HP:0010524) | 2.24136827 |
85 | Rhabdomyosarcoma (HP:0002859) | 2.23662674 |
86 | Cellular immunodeficiency (HP:0005374) | 2.22920808 |
87 | Tracheoesophageal fistula (HP:0002575) | 2.21631406 |
88 | Progressive external ophthalmoplegia (HP:0000590) | 2.19114651 |
89 | 3-Methylglutaconic aciduria (HP:0003535) | 2.16086540 |
90 | Supernumerary spleens (HP:0009799) | 2.15686592 |
91 | Abnormal lung lobation (HP:0002101) | 2.15562354 |
92 | Sloping forehead (HP:0000340) | 2.12865755 |
93 | Abnormality of the umbilical cord (HP:0010881) | 2.12147874 |
94 | Respiratory difficulties (HP:0002880) | 2.07206451 |
95 | Hypoplasia of the radius (HP:0002984) | 2.06073484 |
96 | Sparse lateral eyebrow (HP:0005338) | 2.06019721 |
97 | Squamous cell carcinoma (HP:0002860) | 2.05723354 |
98 | Sparse eyelashes (HP:0000653) | 2.05193124 |
99 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.05036945 |
100 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.05036945 |
101 | Facial cleft (HP:0002006) | 2.04778511 |
102 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.02511678 |
103 | Duplicated collecting system (HP:0000081) | 2.00627145 |
104 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.99668574 |
105 | Amniotic constriction ring (HP:0009775) | 1.98704914 |
106 | Abnormality of placental membranes (HP:0011409) | 1.98704914 |
107 | Stenosis of the external auditory canal (HP:0000402) | 1.98135875 |
108 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.97756667 |
109 | CNS hypomyelination (HP:0003429) | 1.97378837 |
110 | Lethargy (HP:0001254) | 1.97249032 |
111 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.96127411 |
112 | Abnormality of methionine metabolism (HP:0010901) | 1.95961031 |
113 | Abnormality of the duodenum (HP:0002246) | 1.93566711 |
114 | Short thumb (HP:0009778) | 1.92587900 |
115 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.92011100 |
116 | Megaloblastic anemia (HP:0001889) | 1.91709706 |
117 | Basal cell carcinoma (HP:0002671) | 1.90325610 |
118 | Pancytopenia (HP:0001876) | 1.88295424 |
119 | Asplenia (HP:0001746) | 1.87237215 |
120 | Progressive muscle weakness (HP:0003323) | 1.87052225 |
121 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.86333938 |
122 | Ureteral duplication (HP:0000073) | 1.84655366 |
123 | Increased serum lactate (HP:0002151) | 1.84223886 |
124 | Ectopic kidney (HP:0000086) | 1.79500978 |
125 | Sensory axonal neuropathy (HP:0003390) | 1.79068154 |
126 | CNS demyelination (HP:0007305) | 1.78863972 |
127 | Proximal placement of thumb (HP:0009623) | 1.78859034 |
128 | Abnormality of glycolysis (HP:0004366) | 1.78418454 |
129 | Increased serum pyruvate (HP:0003542) | 1.78418454 |
130 | Missing ribs (HP:0000921) | 1.77705148 |
131 | Lymphoma (HP:0002665) | 1.77639203 |
132 | Spastic paraparesis (HP:0002313) | 1.76630709 |
133 | Abnormality of the renal collecting system (HP:0004742) | 1.75841870 |
134 | Irregular epiphyses (HP:0010582) | 1.75719301 |
135 | Depressed nasal ridge (HP:0000457) | 1.75654403 |
136 | Entropion (HP:0000621) | 1.74727220 |
137 | Microvesicular hepatic steatosis (HP:0001414) | 1.74656580 |
138 | Breast aplasia (HP:0100783) | 1.74515999 |
139 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.74384210 |
140 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.74267840 |
141 | Abnormality of abdominal situs (HP:0011620) | 1.73937524 |
142 | Abdominal situs inversus (HP:0003363) | 1.73937524 |
143 | Slender long bone (HP:0003100) | 1.73796947 |
144 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.73250044 |
145 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.73250044 |
146 | Single umbilical artery (HP:0001195) | 1.73250044 |
147 | Congenital, generalized hypertrichosis (HP:0004540) | 1.72056849 |
148 | Progressive microcephaly (HP:0000253) | 1.70852201 |
149 | Exertional dyspnea (HP:0002875) | 1.70467796 |
150 | Abnormality of serum amino acid levels (HP:0003112) | 1.69928844 |
151 | Death in infancy (HP:0001522) | 1.69252373 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.38789271 |
2 | WEE1 | 4.28370393 |
3 | EIF2AK1 | 3.86663001 |
4 | CDC7 | 3.45257061 |
5 | VRK2 | 3.22852325 |
6 | SRPK1 | 3.07567246 |
7 | NME2 | 3.06439719 |
8 | STK16 | 3.01712817 |
9 | TSSK6 | 2.65033376 |
10 | NEK2 | 2.30630842 |
11 | PLK4 | 2.27206803 |
12 | MKNK1 | 2.23133576 |
13 | TTK | 2.22648399 |
14 | TESK2 | 2.05429912 |
15 | EIF2AK3 | 2.02790959 |
16 | MKNK2 | 1.99940508 |
17 | PLK1 | 1.98535741 |
18 | VRK1 | 1.98518148 |
19 | TLK1 | 1.97403112 |
20 | BRSK2 | 1.94655254 |
21 | ACVR1B | 1.90777247 |
22 | EPHA2 | 1.73218318 |
23 | AURKB | 1.70193839 |
24 | PLK3 | 1.69700496 |
25 | DYRK3 | 1.67751820 |
26 | NEK1 | 1.62288401 |
27 | CDK7 | 1.56762728 |
28 | ATR | 1.53707953 |
29 | RPS6KB2 | 1.52637745 |
30 | CHEK2 | 1.48103028 |
31 | PASK | 1.41079573 |
32 | ZAK | 1.39248106 |
33 | PIM2 | 1.37773961 |
34 | RPS6KA4 | 1.37448751 |
35 | MST1R | 1.37335927 |
36 | AURKA | 1.36248683 |
37 | PNCK | 1.30316729 |
38 | MAP3K12 | 1.27583677 |
39 | BCKDK | 1.26083350 |
40 | MAP3K8 | 1.16709359 |
41 | ARAF | 1.15592026 |
42 | BRSK1 | 1.13875051 |
43 | * CHEK1 | 1.11765594 |
44 | PBK | 1.06997977 |
45 | NME1 | 1.02718720 |
46 | CDK4 | 1.00585624 |
47 | ERBB4 | 0.98982555 |
48 | SMG1 | 0.97889963 |
49 | PAK4 | 0.97141370 |
50 | DAPK1 | 0.95717270 |
51 | TGFBR1 | 0.93315873 |
52 | EIF2AK2 | 0.92476291 |
53 | ALK | 0.91690221 |
54 | STK10 | 0.87329738 |
55 | CDK12 | 0.84524066 |
56 | CSNK2A2 | 0.83398761 |
57 | TESK1 | 0.82383638 |
58 | ATM | 0.80292182 |
59 | CDK2 | 0.79902906 |
60 | KDR | 0.76077183 |
61 | TRIM28 | 0.75457502 |
62 | CSNK2A1 | 0.75056760 |
63 | STK4 | 0.73605863 |
64 | LATS2 | 0.73194928 |
65 | PIM1 | 0.73051083 |
66 | PAK1 | 0.72928548 |
67 | PRKCI | 0.64085145 |
68 | IRAK3 | 0.62872609 |
69 | LRRK2 | 0.61829227 |
70 | DYRK2 | 0.61384918 |
71 | RPS6KA5 | 0.61049218 |
72 | TAF1 | 0.60705822 |
73 | CDK8 | 0.60594496 |
74 | MST4 | 0.59499068 |
75 | TAOK2 | 0.59020063 |
76 | CDK1 | 0.58514611 |
77 | STK38L | 0.56820315 |
78 | CCNB1 | 0.56405353 |
79 | MAP2K7 | 0.54992602 |
80 | NUAK1 | 0.54912715 |
81 | BRAF | 0.53849467 |
82 | CSNK1E | 0.50961938 |
83 | MAP3K11 | 0.49500347 |
84 | MELK | 0.49159766 |
85 | LIMK1 | 0.48885296 |
86 | MET | 0.48351624 |
87 | CLK1 | 0.44194659 |
88 | MAPKAPK5 | 0.43145171 |
89 | BRD4 | 0.43087748 |
90 | ILK | 0.42206624 |
91 | AKT3 | 0.40616408 |
92 | PTK2 | 0.39792816 |
93 | EEF2K | 0.38354854 |
94 | CSNK1A1L | 0.37548560 |
95 | MAP2K3 | 0.35320494 |
96 | AKT2 | 0.35145027 |
97 | CDK14 | 0.33458404 |
98 | CSNK1G1 | 0.33423838 |
99 | MAPKAPK3 | 0.32334705 |
100 | CDK11A | 0.31151539 |
101 | CDK6 | 0.31033397 |
102 | SCYL2 | 0.29888344 |
103 | MAP4K1 | 0.29700230 |
104 | PAK2 | 0.29652582 |
105 | PRKDC | 0.29287072 |
106 | CDK18 | 0.28009822 |
107 | DAPK3 | 0.27265246 |
108 | FLT3 | 0.27159191 |
109 | CDK15 | 0.26792059 |
110 | STK3 | 0.26715604 |
111 | ABL2 | 0.26576522 |
112 | LMTK2 | 0.26157925 |
113 | CAMK2G | 0.24091913 |
114 | MAP3K3 | 0.23298957 |
115 | PDK2 | 0.23129412 |
116 | IKBKB | 0.22993279 |
117 | DMPK | 0.22873032 |
118 | CSNK1G2 | 0.22111289 |
119 | MTOR | 0.19766448 |
120 | ZAP70 | 0.17991374 |
121 | MAPK14 | 0.17636615 |
122 | BLK | 0.16624205 |
123 | MARK3 | 0.14478136 |
124 | RAF1 | 0.13877896 |
125 | MAPKAPK2 | 0.13833413 |
126 | CSNK1G3 | 0.13603318 |
127 | CSNK1D | 0.12540081 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.44622021 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.34738592 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.19415357 |
4 | Proteasome_Homo sapiens_hsa03050 | 4.01705373 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 4.00500992 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 3.79628868 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.46456091 |
8 | RNA transport_Homo sapiens_hsa03013 | 3.25557246 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.85352401 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.84155973 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.73201239 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.66170912 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.66073810 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.49453269 |
15 | Cell cycle_Homo sapiens_hsa04110 | 2.41505850 |
16 | Basal transcription factors_Homo sapiens_hsa03022 | 2.16181963 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.14009036 |
18 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.96712689 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.93826011 |
20 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.92176009 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.66231739 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.55045967 |
23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.49364235 |
24 | Purine metabolism_Homo sapiens_hsa00230 | 1.45865249 |
25 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.40389220 |
26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.37621825 |
27 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.30151201 |
28 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.20146431 |
29 | Protein export_Homo sapiens_hsa03060 | 1.06926497 |
30 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.05082234 |
31 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.00928690 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.89910898 |
33 | Huntingtons disease_Homo sapiens_hsa05016 | 0.88426434 |
34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.87761413 |
35 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.87099074 |
36 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.86596793 |
37 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.86564484 |
38 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.85984198 |
39 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.84150692 |
40 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.80279341 |
41 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.79328561 |
42 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78881096 |
43 | Sulfur relay system_Homo sapiens_hsa04122 | 0.77803453 |
44 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.76955224 |
45 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.76775888 |
46 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.76767808 |
47 | Parkinsons disease_Homo sapiens_hsa05012 | 0.71686078 |
48 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.69346357 |
49 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.65527632 |
50 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.61920277 |
51 | HTLV-I infection_Homo sapiens_hsa05166 | 0.61103232 |
52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59715262 |
53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.57956457 |
54 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.57562840 |
55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56917968 |
56 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.56553460 |
57 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.49750289 |
58 | Galactose metabolism_Homo sapiens_hsa00052 | 0.48045313 |
59 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.44012502 |
60 | Legionellosis_Homo sapiens_hsa05134 | 0.43330681 |
61 | Thyroid cancer_Homo sapiens_hsa05216 | 0.43010832 |
62 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.42630726 |
63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42344657 |
64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.41901831 |
65 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.41020787 |
66 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.39993459 |
67 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.39439405 |
68 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.39263179 |
69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.36261082 |
70 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35355257 |
71 | Apoptosis_Homo sapiens_hsa04210 | 0.34074287 |
72 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.33677533 |
73 | Alcoholism_Homo sapiens_hsa05034 | 0.32061341 |
74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.31805314 |
75 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.31354207 |
76 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.31119026 |
77 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.29548640 |
78 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29141066 |
79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29038317 |
80 | Carbon metabolism_Homo sapiens_hsa01200 | 0.27831288 |
81 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27608113 |
82 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.27504732 |
83 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.27341181 |
84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.27245322 |
85 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.26581967 |
86 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26204272 |
87 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26014296 |
88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.25388242 |
89 | Measles_Homo sapiens_hsa05162 | 0.25257838 |
90 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.24599752 |
91 | Shigellosis_Homo sapiens_hsa05131 | 0.22776939 |
92 | Bladder cancer_Homo sapiens_hsa05219 | 0.22450678 |
93 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.21970682 |
94 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.20924902 |
95 | Peroxisome_Homo sapiens_hsa04146 | 0.20870058 |
96 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.19869838 |
97 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.19848770 |
98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.19094414 |
99 | Allograft rejection_Homo sapiens_hsa05330 | 0.18604450 |
100 | Hepatitis B_Homo sapiens_hsa05161 | 0.18223066 |
101 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.17939136 |
102 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.17579895 |
103 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.17352440 |
104 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.16989408 |
105 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.16412979 |
106 | Alzheimers disease_Homo sapiens_hsa05010 | 0.15854285 |
107 | Colorectal cancer_Homo sapiens_hsa05210 | 0.14923256 |
108 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.14455722 |
109 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.14272958 |
110 | Pathways in cancer_Homo sapiens_hsa05200 | 0.13130567 |
111 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.12397033 |
112 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.11455757 |
113 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.10128631 |
114 | Asthma_Homo sapiens_hsa05310 | 0.09985152 |
115 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.09218697 |
116 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.09167843 |
117 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.08775723 |
118 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.07631264 |
119 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.07338641 |
120 | Influenza A_Homo sapiens_hsa05164 | 0.07255735 |
121 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.07133353 |
122 | Viral myocarditis_Homo sapiens_hsa05416 | 0.07076555 |
123 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.06962127 |
124 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.06889071 |
125 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.06153501 |
126 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.06090250 |
127 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.00585421 |
128 | Tight junction_Homo sapiens_hsa04530 | -0.0090318 |
129 | Fatty acid degradation_Homo sapiens_hsa00071 | -0.0081957 |