EBNA1BP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)5.27485542
2ribosomal small subunit assembly (GO:0000028)5.01727529
3ribosomal small subunit biogenesis (GO:0042274)4.81029347
4ribosomal large subunit biogenesis (GO:0042273)4.71819986
5viral transcription (GO:0019083)4.71613307
6translational termination (GO:0006415)4.65664372
7nucleobase biosynthetic process (GO:0046112)4.59863287
8formation of translation preinitiation complex (GO:0001731)4.58161151
9* ribonucleoprotein complex biogenesis (GO:0022613)4.44078771
10purine nucleobase biosynthetic process (GO:0009113)4.39210981
11regulation of mitochondrial translation (GO:0070129)4.38499918
12ribosome assembly (GO:0042255)4.37795586
13establishment of protein localization to mitochondrial membrane (GO:0090151)4.28045390
14* ribosome biogenesis (GO:0042254)4.27023593
15DNA deamination (GO:0045006)4.26634874
16chaperone-mediated protein transport (GO:0072321)4.25613180
17mitotic metaphase plate congression (GO:0007080)4.25582990
18DNA strand elongation involved in DNA replication (GO:0006271)4.24278685
19DNA replication initiation (GO:0006270)4.22370892
20translational elongation (GO:0006414)4.21330411
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.20450096
22translational initiation (GO:0006413)4.19145791
23DNA replication checkpoint (GO:0000076)4.09427231
24rRNA processing (GO:0006364)4.07603991
25DNA strand elongation (GO:0022616)4.04385625
26telomere maintenance via semi-conservative replication (GO:0032201)3.95649814
27rRNA metabolic process (GO:0016072)3.94706342
28spliceosomal snRNP assembly (GO:0000387)3.94490093
29nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.92997881
30SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.91467876
31protein localization to kinetochore (GO:0034501)3.91321074
32proteasome assembly (GO:0043248)3.90440418
33IMP biosynthetic process (GO:0006188)3.82354885
34cotranslational protein targeting to membrane (GO:0006613)3.81951148
35rRNA modification (GO:0000154)3.81281317
36CENP-A containing nucleosome assembly (GO:0034080)3.81059639
37protein targeting to ER (GO:0045047)3.80773549
38protein targeting to mitochondrion (GO:0006626)3.77561652
39chromatin remodeling at centromere (GO:0031055)3.75868488
40nucleobase-containing small molecule interconversion (GO:0015949)3.74353864
41DNA unwinding involved in DNA replication (GO:0006268)3.74012412
42cellular protein complex disassembly (GO:0043624)3.72091124
43establishment of viral latency (GO:0019043)3.67147008
44metaphase plate congression (GO:0051310)3.65581861
45pseudouridine synthesis (GO:0001522)3.65578899
46regulation of translational fidelity (GO:0006450)3.64494553
47viral life cycle (GO:0019058)3.62835819
48DNA replication-dependent nucleosome organization (GO:0034723)3.62269465
49DNA replication-dependent nucleosome assembly (GO:0006335)3.62269465
50establishment of protein localization to endoplasmic reticulum (GO:0072599)3.61891172
51mitotic nuclear envelope disassembly (GO:0007077)3.59628904
52telomere maintenance via recombination (GO:0000722)3.59098323
53ATP synthesis coupled proton transport (GO:0015986)3.58318220
54energy coupled proton transport, down electrochemical gradient (GO:0015985)3.58318220
55transcription elongation from RNA polymerase III promoter (GO:0006385)3.57517866
56termination of RNA polymerase III transcription (GO:0006386)3.57517866
57protein localization to endoplasmic reticulum (GO:0070972)3.56812158
58folic acid-containing compound biosynthetic process (GO:0009396)3.56534971
59DNA replication-independent nucleosome organization (GO:0034724)3.50412056
60DNA replication-independent nucleosome assembly (GO:0006336)3.50412056
61regulation of cellular amino acid metabolic process (GO:0006521)3.49732458
62regulation of translational termination (GO:0006449)3.49171175
63negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.49083375
64transcription elongation from RNA polymerase I promoter (GO:0006362)3.47709014
65termination of RNA polymerase I transcription (GO:0006363)3.46676277
66protein localization to mitochondrion (GO:0070585)3.45167769
67kinetochore organization (GO:0051383)3.45145191
68spliceosomal complex assembly (GO:0000245)3.45101850
69establishment of protein localization to mitochondrion (GO:0072655)3.44905889
70anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.43419864
71translation (GO:0006412)3.42657864
72nuclear pore organization (GO:0006999)3.42218670
73mitotic recombination (GO:0006312)3.40678551
74positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.39505302
75tRNA aminoacylation for protein translation (GO:0006418)3.39456673
76regulation of spindle organization (GO:0090224)3.39408027
77regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.39172250
78regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.37960456
79positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.36695012
80tRNA aminoacylation (GO:0043039)3.34735759
81amino acid activation (GO:0043038)3.34735759
82telomere maintenance via telomere lengthening (GO:0010833)3.34652267
83* cellular component biogenesis (GO:0044085)3.34073319
84protein localization to chromosome, centromeric region (GO:0071459)3.33984877
85protein complex disassembly (GO:0043241)3.32898870
86maturation of 5.8S rRNA (GO:0000460)3.32689318
87kinetochore assembly (GO:0051382)3.32449270
88membrane disassembly (GO:0030397)3.31270668
89nuclear envelope disassembly (GO:0051081)3.31270668
90transcription-coupled nucleotide-excision repair (GO:0006283)3.30916754
91IMP metabolic process (GO:0046040)3.30483772
92transcription from RNA polymerase I promoter (GO:0006360)3.28738898
937-methylguanosine mRNA capping (GO:0006370)3.27550850
94mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.26684653
95establishment of integrated proviral latency (GO:0075713)3.25862157
96positive regulation of ligase activity (GO:0051351)3.25832518
97signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.25717085
98intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.25717085
99signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25532039
100signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25532039
101signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25532039
102signal transduction involved in DNA integrity checkpoint (GO:0072401)3.25185751
103signal transduction involved in DNA damage checkpoint (GO:0072422)3.25185751
104histone exchange (GO:0043486)3.22076130
105RNA capping (GO:0036260)3.21786344
1067-methylguanosine RNA capping (GO:0009452)3.21786344
107negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.20214978
108negative regulation of ligase activity (GO:0051352)3.20214978
109transcription from mitochondrial promoter (GO:0006390)3.18862915
110mitochondrial RNA metabolic process (GO:0000959)3.18052078
111signal transduction involved in cell cycle checkpoint (GO:0072395)3.18030862
112protein maturation by protein folding (GO:0022417)3.17715356
113macromolecular complex disassembly (GO:0032984)3.17524858
114regulation of ubiquitin-protein transferase activity (GO:0051438)3.16668668
115nuclear-transcribed mRNA catabolic process (GO:0000956)3.15818910
116respiratory electron transport chain (GO:0022904)3.14432321
117establishment of chromosome localization (GO:0051303)3.14133571
118deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.11488855
119viral mRNA export from host cell nucleus (GO:0046784)3.10324394
120nuclear pore complex assembly (GO:0051292)3.10246793
121pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.09824535
122regulation of nuclear cell cycle DNA replication (GO:0033262)3.09091562
123nucleotide-excision repair, DNA gap filling (GO:0006297)3.07939235
124folic acid metabolic process (GO:0046655)3.07477364
125ncRNA processing (GO:0034470)3.06795377
126electron transport chain (GO:0022900)3.06751225
127regulation of ligase activity (GO:0051340)3.06107545
128cell cycle G1/S phase transition (GO:0044843)3.05435089
129G1/S transition of mitotic cell cycle (GO:0000082)3.05435089
130DNA damage response, detection of DNA damage (GO:0042769)3.02283850
131mitotic chromosome condensation (GO:0007076)3.01932114
132rRNA methylation (GO:0031167)3.01533627
133transcription initiation from RNA polymerase I promoter (GO:0006361)3.01436228
134pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.00972837
135tRNA methylation (GO:0030488)3.00299774
136attachment of spindle microtubules to kinetochore (GO:0008608)3.00076129
137RNA splicing, via transesterification reactions (GO:0000375)2.99608730
138mRNA catabolic process (GO:0006402)2.99553388
139DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.99358963
140mitotic sister chromatid segregation (GO:0000070)2.99306109
141DNA-templated transcription, termination (GO:0006353)2.99197118

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.61615116
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.81999794
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.75447769
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.59173848
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.48713722
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.44834360
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.42464282
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.36006286
9* GABP_17652178_ChIP-ChIP_JURKAT_Human3.25615507
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.22154274
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.16796599
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.08320851
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.07347295
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.98790544
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.98312116
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.65472283
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.53042267
18XRN2_22483619_ChIP-Seq_HELA_Human2.52457396
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.46669734
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.44284339
21VDR_23849224_ChIP-Seq_CD4+_Human2.42527438
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.41708046
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.16660387
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.15864209
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.14282235
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.12814646
27DCP1A_22483619_ChIP-Seq_HELA_Human2.12431405
28FOXP3_21729870_ChIP-Seq_TREG_Human2.08438469
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.06067110
30TTF2_22483619_ChIP-Seq_HELA_Human2.04415354
31AR_21909140_ChIP-Seq_LNCAP_Human1.99730708
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95718166
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95586682
34* GABP_19822575_ChIP-Seq_HepG2_Human1.92173847
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.91029074
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.89526138
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.89466858
38POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88773863
39ELK1_19687146_ChIP-ChIP_HELA_Human1.87339040
40E2F1_21310950_ChIP-Seq_MCF-7_Human1.81244161
41ZNF263_19887448_ChIP-Seq_K562_Human1.77929032
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73533607
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.73447638
44KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.70398579
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.69441615
46SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.61482933
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60510985
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.60224922
49* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49567839
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.48443388
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.47716217
52KDM5A_27292631_Chip-Seq_BREAST_Human1.45045617
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44206116
54POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.42628658
55CIITA_25753668_ChIP-Seq_RAJI_Human1.41680308
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.37747156
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.37259057
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.33702009
59TP63_19390658_ChIP-ChIP_HaCaT_Human1.32241953
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.31874635
61SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.31453159
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.28876738
63STAT3_1855785_ChIP-Seq_MESCs_Mouse1.24450900
64KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22883084
65CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.22054947
66SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20681934
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18691539
68ELK1_22589737_ChIP-Seq_MCF10A_Human1.18647852
69SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.17915441
70* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15901460
71MYC_22102868_ChIP-Seq_BL_Human1.15383731
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.14983855
73HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13909221
74CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13337189
75* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.12492835
76PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.12402314
77* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11763026
78MYC_18940864_ChIP-ChIP_HL60_Human1.07651027
79DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.06720802
80* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05848446
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04440988
82SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03889936
83TFEB_21752829_ChIP-Seq_HELA_Human1.03596797
84PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01622300
85* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00186309
86HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.98818368
87TCF3_18692474_ChIP-Seq_MEFs_Mouse0.98683999
88KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97837956
89KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.97007058
90KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.97007058
91KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.97007058
92PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.95474811
93SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.95279483
94RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95068079
95TBX5_21415370_ChIP-Seq_HL-1_Mouse0.95018125
96BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94882181
97CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.94843256
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.93278239
99SOX17_20123909_ChIP-Seq_XEN_Mouse0.92333874
100TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.91268232
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.90331127
102* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89417313
103ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.89285486
104TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.88766645
105NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.86707133
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.86334135
107DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.86280065
108OCT4_18692474_ChIP-Seq_MEFs_Mouse0.85385594
109FOXP1_21924763_ChIP-Seq_HESCs_Human0.84209539
110SOX2_18692474_ChIP-Seq_MEFs_Mouse0.84058543
111CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83665068
112NANOG_21062744_ChIP-ChIP_HESCs_Human0.82660706
113NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.82530962
114ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81747290
115CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.80513570
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80177634
117GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.79783992
118CTCF_18555785_ChIP-Seq_MESCs_Mouse0.77759281

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.01002234
2MP0004957_abnormal_blastocyst_morpholog4.87262469
3MP0003111_abnormal_nucleus_morphology4.69639145
4MP0010094_abnormal_chromosome_stability4.61969998
5MP0003077_abnormal_cell_cycle4.18528417
6MP0008057_abnormal_DNA_replication3.88920628
7MP0008058_abnormal_DNA_repair3.73365056
8MP0008007_abnormal_cellular_replicative3.10196079
9MP0008932_abnormal_embryonic_tissue2.99256199
10MP0002877_abnormal_melanocyte_morpholog2.52774075
11MP0009697_abnormal_copulation2.49575482
12MP0001730_embryonic_growth_arrest2.42604497
13MP0003786_premature_aging2.39967637
14MP0003123_paternal_imprinting2.33272478
15MP0000350_abnormal_cell_proliferation2.30859061
16MP0003718_maternal_effect2.23751039
17MP0008877_abnormal_DNA_methylation2.14587999
18MP0002396_abnormal_hematopoietic_system2.05551573
19MP0001672_abnormal_embryogenesis/_devel1.74538385
20MP0005380_embryogenesis_phenotype1.74538385
21MP0001697_abnormal_embryo_size1.72451625
22MP0002080_prenatal_lethality1.63564931
23MP0010352_gastrointestinal_tract_polyps1.61848049
24MP0010030_abnormal_orbit_morphology1.60908695
25MP0003806_abnormal_nucleotide_metabolis1.58005645
26MP0010307_abnormal_tumor_latency1.57732206
27MP0002085_abnormal_embryonic_tissue1.57088118
28MP0009379_abnormal_foot_pigmentation1.56046541
29MP0006292_abnormal_olfactory_placode1.52222461
30MP0003941_abnormal_skin_development1.51777478
31MP0003984_embryonic_growth_retardation1.50789110
32MP0000490_abnormal_crypts_of1.49984647
33MP0000313_abnormal_cell_death1.47369170
34MP0002088_abnormal_embryonic_growth/wei1.46585543
35MP0009333_abnormal_splenocyte_physiolog1.43250128
36MP0002084_abnormal_developmental_patter1.42284551
37MP0003950_abnormal_plasma_membrane1.37587753
38MP0002234_abnormal_pharynx_morphology1.35317525
39MP0004197_abnormal_fetal_growth/weight/1.34797798
40MP0003315_abnormal_perineum_morphology1.33212881
41MP0005623_abnormal_meninges_morphology1.32750605
42MP0002019_abnormal_tumor_incidence1.32599360
43MP0001293_anophthalmia1.29065449
44MP0002086_abnormal_extraembryonic_tissu1.28989955
45MP0003567_abnormal_fetal_cardiomyocyte1.24669817
46MP0001529_abnormal_vocalization1.24135105
47MP0002210_abnormal_sex_determination1.23795275
48MP0004233_abnormal_muscle_weight1.19678669
49MP0003890_abnormal_embryonic-extraembry1.18915637
50MP0004808_abnormal_hematopoietic_stem1.18474932
51MP0001881_abnormal_mammary_gland1.17295868
52MP0002132_abnormal_respiratory_system1.16615177
53MP0001661_extended_life_span1.15677726
54MP0000678_abnormal_parathyroid_gland1.14156652
55MP0001145_abnormal_male_reproductive1.10822274
56MP0003121_genomic_imprinting1.08687587
57MP0004133_heterotaxia1.08437683
58MP0002160_abnormal_reproductive_system1.06725169
59MP0002796_impaired_skin_barrier1.06038737
60MP0003763_abnormal_thymus_physiology1.02851144
61MP0003186_abnormal_redox_activity1.00330240
62MP0000703_abnormal_thymus_morphology1.00284829
63MP0000537_abnormal_urethra_morphology0.97666152
64MP0000358_abnormal_cell_content/0.97639902
65MP0000762_abnormal_tongue_morphology0.92953363
66MP0005408_hypopigmentation0.92212078
67MP0000653_abnormal_sex_gland0.92132877
68MP0005330_cardiomyopathy0.90706581
69MP0003119_abnormal_digestive_system0.90369052
70MP0002653_abnormal_ependyma_morphology0.89333481
71MP0001929_abnormal_gametogenesis0.88106377
72MP0005389_reproductive_system_phenotype0.88027689
73MP0002102_abnormal_ear_morphology0.86400024
74MP0000750_abnormal_muscle_regeneration0.84884128
75MP0000579_abnormal_nail_morphology0.84656928
76MP0002938_white_spotting0.83812401
77MP0002722_abnormal_immune_system0.82983853
78MP0002111_abnormal_tail_morphology0.82831184
79MP0005397_hematopoietic_system_phenotyp0.82377611
80MP0001545_abnormal_hematopoietic_system0.82377611
81MP0002398_abnormal_bone_marrow0.80929910
82MP0000858_altered_metastatic_potential0.80883081
83MP0008789_abnormal_olfactory_epithelium0.80240215
84MP0005384_cellular_phenotype0.78375511
85MP0002177_abnormal_outer_ear0.78212328
86MP0003937_abnormal_limbs/digits/tail_de0.77590217
87MP0001286_abnormal_eye_development0.77300188
88MP0002060_abnormal_skin_morphology0.77190484
89MP0005076_abnormal_cell_differentiation0.76005532
90MP0006035_abnormal_mitochondrial_morpho0.75690873
91MP0000627_abnormal_mammary_gland0.75206730
92MP0001119_abnormal_female_reproductive0.75151663
93MP0000689_abnormal_spleen_morphology0.73235889
94MP0003136_yellow_coat_color0.73193771
95MP0002269_muscular_atrophy0.71764579
96MP0005621_abnormal_cell_physiology0.71119439
97MP0003385_abnormal_body_wall0.70726767
98MP0002697_abnormal_eye_size0.70189741
99MP0009672_abnormal_birth_weight0.69965424
100MP0008875_abnormal_xenobiotic_pharmacok0.69073413
101MP0000647_abnormal_sebaceous_gland0.68282096
102MP0001919_abnormal_reproductive_system0.68101390
103MP0000428_abnormal_craniofacial_morphol0.66700162
104MP0000372_irregular_coat_pigmentation0.65156058
105MP0005257_abnormal_intraocular_pressure0.65134258
106MP0001853_heart_inflammation0.64056541
107MP0001764_abnormal_homeostasis0.63706294
108MP0002163_abnormal_gland_morphology0.63358625
109MP0005501_abnormal_skin_physiology0.62978094
110MP0002429_abnormal_blood_cell0.62521811
111MP0000049_abnormal_middle_ear0.62179893
112MP0010771_integument_phenotype0.62141076
113MP0005023_abnormal_wound_healing0.60952487
114MP0003221_abnormal_cardiomyocyte_apopto0.60874764
115MP0009053_abnormal_anal_canal0.60577383
116MP0005395_other_phenotype0.60513659
117MP0000467_abnormal_esophagus_morphology0.59605803
118MP0003938_abnormal_ear_development0.58993395
119MP0001727_abnormal_embryo_implantation0.58586183
120MP0004185_abnormal_adipocyte_glucose0.57598053
121MP0000432_abnormal_head_morphology0.57316110
122MP0000749_muscle_degeneration0.57113334
123MP0009703_decreased_birth_body0.56430550
124MP0002161_abnormal_fertility/fecundity0.56403069
125MP0002092_abnormal_eye_morphology0.55995003
126MP0008873_increased_physiological_sensi0.55758836
127MP0005410_abnormal_fertilization0.55586411
128MP0003936_abnormal_reproductive_system0.55505324
129MP0009250_abnormal_appendicular_skeleto0.54651588
130MP0005084_abnormal_gallbladder_morpholo0.53396537
131MP0008260_abnormal_autophagy0.52847027
132MP0001915_intracranial_hemorrhage0.51534422
133MP0001216_abnormal_epidermal_layer0.51381565
134MP0001243_abnormal_dermal_layer0.51326293
135MP0002114_abnormal_axial_skeleton0.50792420
136MP0002751_abnormal_autonomic_nervous0.50143686
137MP0006036_abnormal_mitochondrial_physio0.49113427

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.19138503
2Reticulocytopenia (HP:0001896)5.10565940
3Abnormality of cells of the erythroid lineage (HP:0012130)5.07460671
4Acute necrotizing encephalopathy (HP:0006965)4.81750231
5Abnormal number of erythroid precursors (HP:0012131)4.73418303
6Abnormal mitochondria in muscle tissue (HP:0008316)4.69531922
7Breast hypoplasia (HP:0003187)4.41120267
8Acute encephalopathy (HP:0006846)4.30329836
9Increased CSF lactate (HP:0002490)3.90636713
10Mitochondrial inheritance (HP:0001427)3.84622395
11Macrocytic anemia (HP:0001972)3.83672232
12Progressive macrocephaly (HP:0004481)3.75024022
13Carpal bone hypoplasia (HP:0001498)3.64011889
14Oral leukoplakia (HP:0002745)3.60758309
15Cerebral edema (HP:0002181)3.56674530
16Rough bone trabeculation (HP:0100670)3.53814287
17Cerebral hypomyelination (HP:0006808)3.50547259
18Increased hepatocellular lipid droplets (HP:0006565)3.46006161
19Chromsome breakage (HP:0040012)3.39995497
20Patellar aplasia (HP:0006443)3.39264185
21Pallor (HP:0000980)3.38285581
22Hepatocellular necrosis (HP:0001404)3.31631050
23Colon cancer (HP:0003003)3.29464763
24Aplasia/Hypoplasia of the patella (HP:0006498)3.22022238
25Chromosomal breakage induced by crosslinking agents (HP:0003221)3.20499586
26Degeneration of anterior horn cells (HP:0002398)3.19979800
27Abnormality of the anterior horn cell (HP:0006802)3.19979800
28Lipid accumulation in hepatocytes (HP:0006561)3.16693070
29Hepatic necrosis (HP:0002605)3.16149305
30Selective tooth agenesis (HP:0001592)3.06189623
31Trismus (HP:0000211)3.02395218
32Meckel diverticulum (HP:0002245)3.00988792
33Abnormality of the preputium (HP:0100587)2.99712829
34Absent radius (HP:0003974)2.97884096
35Lactic acidosis (HP:0003128)2.94772024
36Absent thumb (HP:0009777)2.94716069
37Increased intramyocellular lipid droplets (HP:0012240)2.90133012
38Type I transferrin isoform profile (HP:0003642)2.88842728
39Exercise intolerance (HP:0003546)2.86892695
40Abnormality of the ileum (HP:0001549)2.83026878
41Aplastic anemia (HP:0001915)2.82282275
42Hyperalaninemia (HP:0003348)2.78049538
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.78049538
44Abnormality of alanine metabolism (HP:0010916)2.78049538
45Multiple enchondromatosis (HP:0005701)2.76729579
46Absent forearm bone (HP:0003953)2.76093181
47Aplasia involving forearm bones (HP:0009822)2.76093181
48Abnormality of the labia minora (HP:0012880)2.71077726
49Premature graying of hair (HP:0002216)2.70328597
50Abnormality of chromosome stability (HP:0003220)2.69159969
51Renal Fanconi syndrome (HP:0001994)2.66689234
52Impulsivity (HP:0100710)2.63494468
53Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.60789619
54Horseshoe kidney (HP:0000085)2.60038978
55Testicular atrophy (HP:0000029)2.60022955
56Abnormal trabecular bone morphology (HP:0100671)2.59456641
57Aplasia/Hypoplasia of the uvula (HP:0010293)2.55841998
58Medulloblastoma (HP:0002885)2.52277461
59Reduced antithrombin III activity (HP:0001976)2.49477276
60Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.49115836
61Respiratory failure (HP:0002878)2.48878906
62Premature ovarian failure (HP:0008209)2.44628284
63Neoplasm of the pancreas (HP:0002894)2.43722338
6411 pairs of ribs (HP:0000878)2.42426720
65Cleft eyelid (HP:0000625)2.42257248
66Myelodysplasia (HP:0002863)2.41544081
67Microretrognathia (HP:0000308)2.38675066
68Leukodystrophy (HP:0002415)2.37957045
69Ragged-red muscle fibers (HP:0003200)2.35958387
70Increased muscle lipid content (HP:0009058)2.35447879
71Triphalangeal thumb (HP:0001199)2.35231304
72Small intestinal stenosis (HP:0012848)2.35140485
73Duodenal stenosis (HP:0100867)2.35140485
74Abnormal protein glycosylation (HP:0012346)2.33861982
75Abnormal glycosylation (HP:0012345)2.33861982
76Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.33861982
77Abnormal protein N-linked glycosylation (HP:0012347)2.33861982
78Glossoptosis (HP:0000162)2.33287531
79Bone marrow hypocellularity (HP:0005528)2.30915881
80Ependymoma (HP:0002888)2.30891953
81Atresia of the external auditory canal (HP:0000413)2.28419001
82Secondary amenorrhea (HP:0000869)2.26739710
83Abnormal number of incisors (HP:0011064)2.25326201
84Agnosia (HP:0010524)2.24136827
85Rhabdomyosarcoma (HP:0002859)2.23662674
86Cellular immunodeficiency (HP:0005374)2.22920808
87Tracheoesophageal fistula (HP:0002575)2.21631406
88Progressive external ophthalmoplegia (HP:0000590)2.19114651
893-Methylglutaconic aciduria (HP:0003535)2.16086540
90Supernumerary spleens (HP:0009799)2.15686592
91Abnormal lung lobation (HP:0002101)2.15562354
92Sloping forehead (HP:0000340)2.12865755
93Abnormality of the umbilical cord (HP:0010881)2.12147874
94Respiratory difficulties (HP:0002880)2.07206451
95Hypoplasia of the radius (HP:0002984)2.06073484
96Sparse lateral eyebrow (HP:0005338)2.06019721
97Squamous cell carcinoma (HP:0002860)2.05723354
98Sparse eyelashes (HP:0000653)2.05193124
99Decreased activity of mitochondrial respiratory chain (HP:0008972)2.05036945
100Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.05036945
101Facial cleft (HP:0002006)2.04778511
102Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02511678
103Duplicated collecting system (HP:0000081)2.00627145
104Abnormalities of placenta or umbilical cord (HP:0001194)1.99668574
105Amniotic constriction ring (HP:0009775)1.98704914
106Abnormality of placental membranes (HP:0011409)1.98704914
107Stenosis of the external auditory canal (HP:0000402)1.98135875
108Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.97756667
109CNS hypomyelination (HP:0003429)1.97378837
110Lethargy (HP:0001254)1.97249032
111Reduced subcutaneous adipose tissue (HP:0003758)1.96127411
112Abnormality of methionine metabolism (HP:0010901)1.95961031
113Abnormality of the duodenum (HP:0002246)1.93566711
114Short thumb (HP:0009778)1.92587900
115Aplasia/hypoplasia of the humerus (HP:0006507)1.92011100
116Megaloblastic anemia (HP:0001889)1.91709706
117Basal cell carcinoma (HP:0002671)1.90325610
118Pancytopenia (HP:0001876)1.88295424
119Asplenia (HP:0001746)1.87237215
120Progressive muscle weakness (HP:0003323)1.87052225
121Atrophy/Degeneration involving motor neurons (HP:0007373)1.86333938
122Ureteral duplication (HP:0000073)1.84655366
123Increased serum lactate (HP:0002151)1.84223886
124Ectopic kidney (HP:0000086)1.79500978
125Sensory axonal neuropathy (HP:0003390)1.79068154
126CNS demyelination (HP:0007305)1.78863972
127Proximal placement of thumb (HP:0009623)1.78859034
128Abnormality of glycolysis (HP:0004366)1.78418454
129Increased serum pyruvate (HP:0003542)1.78418454
130Missing ribs (HP:0000921)1.77705148
131Lymphoma (HP:0002665)1.77639203
132Spastic paraparesis (HP:0002313)1.76630709
133Abnormality of the renal collecting system (HP:0004742)1.75841870
134Irregular epiphyses (HP:0010582)1.75719301
135Depressed nasal ridge (HP:0000457)1.75654403
136Entropion (HP:0000621)1.74727220
137Microvesicular hepatic steatosis (HP:0001414)1.74656580
138Breast aplasia (HP:0100783)1.74515999
139Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74384210
140Aplasia/Hypoplasia involving the musculature (HP:0001460)1.74267840
141Abnormality of abdominal situs (HP:0011620)1.73937524
142Abdominal situs inversus (HP:0003363)1.73937524
143Slender long bone (HP:0003100)1.73796947
144Abnormality of the fetal cardiovascular system (HP:0010948)1.73250044
145Abnormal umbilical cord blood vessels (HP:0011403)1.73250044
146Single umbilical artery (HP:0001195)1.73250044
147Congenital, generalized hypertrichosis (HP:0004540)1.72056849
148Progressive microcephaly (HP:0000253)1.70852201
149Exertional dyspnea (HP:0002875)1.70467796
150Abnormality of serum amino acid levels (HP:0003112)1.69928844
151Death in infancy (HP:0001522)1.69252373

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.38789271
2WEE14.28370393
3EIF2AK13.86663001
4CDC73.45257061
5VRK23.22852325
6SRPK13.07567246
7NME23.06439719
8STK163.01712817
9TSSK62.65033376
10NEK22.30630842
11PLK42.27206803
12MKNK12.23133576
13TTK2.22648399
14TESK22.05429912
15EIF2AK32.02790959
16MKNK21.99940508
17PLK11.98535741
18VRK11.98518148
19TLK11.97403112
20BRSK21.94655254
21ACVR1B1.90777247
22EPHA21.73218318
23AURKB1.70193839
24PLK31.69700496
25DYRK31.67751820
26NEK11.62288401
27CDK71.56762728
28ATR1.53707953
29RPS6KB21.52637745
30CHEK21.48103028
31PASK1.41079573
32ZAK1.39248106
33PIM21.37773961
34RPS6KA41.37448751
35MST1R1.37335927
36AURKA1.36248683
37PNCK1.30316729
38MAP3K121.27583677
39BCKDK1.26083350
40MAP3K81.16709359
41ARAF1.15592026
42BRSK11.13875051
43* CHEK11.11765594
44PBK1.06997977
45NME11.02718720
46CDK41.00585624
47ERBB40.98982555
48SMG10.97889963
49PAK40.97141370
50DAPK10.95717270
51TGFBR10.93315873
52EIF2AK20.92476291
53ALK0.91690221
54STK100.87329738
55CDK120.84524066
56CSNK2A20.83398761
57TESK10.82383638
58ATM0.80292182
59CDK20.79902906
60KDR0.76077183
61TRIM280.75457502
62CSNK2A10.75056760
63STK40.73605863
64LATS20.73194928
65PIM10.73051083
66PAK10.72928548
67PRKCI0.64085145
68IRAK30.62872609
69LRRK20.61829227
70DYRK20.61384918
71RPS6KA50.61049218
72TAF10.60705822
73CDK80.60594496
74MST40.59499068
75TAOK20.59020063
76CDK10.58514611
77STK38L0.56820315
78CCNB10.56405353
79MAP2K70.54992602
80NUAK10.54912715
81BRAF0.53849467
82CSNK1E0.50961938
83MAP3K110.49500347
84MELK0.49159766
85LIMK10.48885296
86MET0.48351624
87CLK10.44194659
88MAPKAPK50.43145171
89BRD40.43087748
90ILK0.42206624
91AKT30.40616408
92PTK20.39792816
93EEF2K0.38354854
94CSNK1A1L0.37548560
95MAP2K30.35320494
96AKT20.35145027
97CDK140.33458404
98CSNK1G10.33423838
99MAPKAPK30.32334705
100CDK11A0.31151539
101CDK60.31033397
102SCYL20.29888344
103MAP4K10.29700230
104PAK20.29652582
105PRKDC0.29287072
106CDK180.28009822
107DAPK30.27265246
108FLT30.27159191
109CDK150.26792059
110STK30.26715604
111ABL20.26576522
112LMTK20.26157925
113CAMK2G0.24091913
114MAP3K30.23298957
115PDK20.23129412
116IKBKB0.22993279
117DMPK0.22873032
118CSNK1G20.22111289
119MTOR0.19766448
120ZAP700.17991374
121MAPK140.17636615
122BLK0.16624205
123MARK30.14478136
124RAF10.13877896
125MAPKAPK20.13833413
126CSNK1G30.13603318
127CSNK1D0.12540081

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.44622021
2DNA replication_Homo sapiens_hsa030304.34738592
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.19415357
4Proteasome_Homo sapiens_hsa030504.01705373
5RNA polymerase_Homo sapiens_hsa030204.00500992
6Mismatch repair_Homo sapiens_hsa034303.79628868
7Spliceosome_Homo sapiens_hsa030403.46456091
8RNA transport_Homo sapiens_hsa030133.25557246
9Nucleotide excision repair_Homo sapiens_hsa034202.85352401
10Homologous recombination_Homo sapiens_hsa034402.84155973
11Base excision repair_Homo sapiens_hsa034102.73201239
12Pyrimidine metabolism_Homo sapiens_hsa002402.66170912
13One carbon pool by folate_Homo sapiens_hsa006702.66073810
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.49453269
15Cell cycle_Homo sapiens_hsa041102.41505850
16Basal transcription factors_Homo sapiens_hsa030222.16181963
17Fanconi anemia pathway_Homo sapiens_hsa034602.14009036
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.96712689
19RNA degradation_Homo sapiens_hsa030181.93826011
20Non-homologous end-joining_Homo sapiens_hsa034501.92176009
21mRNA surveillance pathway_Homo sapiens_hsa030151.66231739
22p53 signaling pathway_Homo sapiens_hsa041151.55045967
23Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.49364235
24Purine metabolism_Homo sapiens_hsa002301.45865249
25Pyruvate metabolism_Homo sapiens_hsa006201.40389220
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.37621825
27Epstein-Barr virus infection_Homo sapiens_hsa051691.30151201
28Vitamin B6 metabolism_Homo sapiens_hsa007501.20146431
29Protein export_Homo sapiens_hsa030601.06926497
30Fatty acid elongation_Homo sapiens_hsa000621.05082234
31Systemic lupus erythematosus_Homo sapiens_hsa053221.00928690
32Cyanoamino acid metabolism_Homo sapiens_hsa004600.89910898
33Huntingtons disease_Homo sapiens_hsa050160.88426434
34Cysteine and methionine metabolism_Homo sapiens_hsa002700.87761413
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.87099074
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.86596793
37Folate biosynthesis_Homo sapiens_hsa007900.86564484
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85984198
39Pentose phosphate pathway_Homo sapiens_hsa000300.84150692
40Herpes simplex infection_Homo sapiens_hsa051680.80279341
41Viral carcinogenesis_Homo sapiens_hsa052030.79328561
42Sulfur metabolism_Homo sapiens_hsa009200.78881096
43Sulfur relay system_Homo sapiens_hsa041220.77803453
44Oocyte meiosis_Homo sapiens_hsa041140.76955224
45Antigen processing and presentation_Homo sapiens_hsa046120.76775888
46Cardiac muscle contraction_Homo sapiens_hsa042600.76767808
47Parkinsons disease_Homo sapiens_hsa050120.71686078
48Biosynthesis of amino acids_Homo sapiens_hsa012300.69346357
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.65527632
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61920277
51HTLV-I infection_Homo sapiens_hsa051660.61103232
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59715262
53Glutathione metabolism_Homo sapiens_hsa004800.57956457
54Propanoate metabolism_Homo sapiens_hsa006400.57562840
55Selenocompound metabolism_Homo sapiens_hsa004500.56917968
56Oxidative phosphorylation_Homo sapiens_hsa001900.56553460
57Steroid biosynthesis_Homo sapiens_hsa001000.49750289
58Galactose metabolism_Homo sapiens_hsa000520.48045313
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.44012502
60Legionellosis_Homo sapiens_hsa051340.43330681
61Thyroid cancer_Homo sapiens_hsa052160.43010832
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42630726
63Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42344657
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41901831
65Small cell lung cancer_Homo sapiens_hsa052220.41020787
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39993459
67MicroRNAs in cancer_Homo sapiens_hsa052060.39439405
68Primary immunodeficiency_Homo sapiens_hsa053400.39263179
69Phenylalanine metabolism_Homo sapiens_hsa003600.36261082
70TGF-beta signaling pathway_Homo sapiens_hsa043500.35355257
71Apoptosis_Homo sapiens_hsa042100.34074287
72Tyrosine metabolism_Homo sapiens_hsa003500.33677533
73Alcoholism_Homo sapiens_hsa050340.32061341
74Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.31805314
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31354207
76Vibrio cholerae infection_Homo sapiens_hsa051100.31119026
77Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29548640
78Hippo signaling pathway_Homo sapiens_hsa043900.29141066
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29038317
80Carbon metabolism_Homo sapiens_hsa012000.27831288
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27608113
82Fructose and mannose metabolism_Homo sapiens_hsa000510.27504732
83Arginine biosynthesis_Homo sapiens_hsa002200.27341181
84Arachidonic acid metabolism_Homo sapiens_hsa005900.27245322
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.26581967
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.26204272
87Metabolic pathways_Homo sapiens_hsa011000.26014296
88Regulation of autophagy_Homo sapiens_hsa041400.25388242
89Measles_Homo sapiens_hsa051620.25257838
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24599752
91Shigellosis_Homo sapiens_hsa051310.22776939
92Bladder cancer_Homo sapiens_hsa052190.22450678
93Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.21970682
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.20924902
95Peroxisome_Homo sapiens_hsa041460.20870058
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.19869838
97Basal cell carcinoma_Homo sapiens_hsa052170.19848770
98N-Glycan biosynthesis_Homo sapiens_hsa005100.19094414
99Allograft rejection_Homo sapiens_hsa053300.18604450
100Hepatitis B_Homo sapiens_hsa051610.18223066
101Graft-versus-host disease_Homo sapiens_hsa053320.17939136
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.17579895
103Central carbon metabolism in cancer_Homo sapiens_hsa052300.17352440
104HIF-1 signaling pathway_Homo sapiens_hsa040660.16989408
105Fatty acid metabolism_Homo sapiens_hsa012120.16412979
106Alzheimers disease_Homo sapiens_hsa050100.15854285
107Colorectal cancer_Homo sapiens_hsa052100.14923256
108Arginine and proline metabolism_Homo sapiens_hsa003300.14455722
109beta-Alanine metabolism_Homo sapiens_hsa004100.14272958
110Pathways in cancer_Homo sapiens_hsa052000.13130567
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12397033
112Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.11455757
113Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.10128631
114Asthma_Homo sapiens_hsa053100.09985152
115Hematopoietic cell lineage_Homo sapiens_hsa046400.09218697
116Notch signaling pathway_Homo sapiens_hsa043300.09167843
117Hedgehog signaling pathway_Homo sapiens_hsa043400.08775723
1182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.07631264
119RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.07338641
120Influenza A_Homo sapiens_hsa051640.07255735
121Autoimmune thyroid disease_Homo sapiens_hsa053200.07133353
122Viral myocarditis_Homo sapiens_hsa054160.07076555
123Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.06962127
124SNARE interactions in vesicular transport_Homo sapiens_hsa041300.06889071
125Type I diabetes mellitus_Homo sapiens_hsa049400.06153501
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.06090250
127Chemical carcinogenesis_Homo sapiens_hsa052040.00585421
128Tight junction_Homo sapiens_hsa04530-0.0090318
129Fatty acid degradation_Homo sapiens_hsa00071-0.0081957

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