ECT2L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)8.81185519
2regulation of cilium movement (GO:0003352)8.68273840
3axoneme assembly (GO:0035082)8.21960269
4left/right pattern formation (GO:0060972)7.86350625
5GTP biosynthetic process (GO:0006183)7.67112584
6motile cilium assembly (GO:0044458)7.30139599
7epithelial cilium movement (GO:0003351)6.95973155
8UTP biosynthetic process (GO:0006228)6.60211504
9UTP metabolic process (GO:0046051)6.30609625
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.29620943
11primary alcohol catabolic process (GO:0034310)5.86100897
12nucleoside diphosphate phosphorylation (GO:0006165)5.68668934
13vitamin transmembrane transport (GO:0035461)5.60452865
14diterpenoid biosynthetic process (GO:0016102)5.35812808
15fusion of sperm to egg plasma membrane (GO:0007342)5.30400531
16protein localization to cilium (GO:0061512)5.18517506
17ventricular system development (GO:0021591)5.17988653
18regulation of microtubule-based movement (GO:0060632)5.14374277
19ethanol metabolic process (GO:0006067)5.03607573
20CTP metabolic process (GO:0046036)4.97864849
21CTP biosynthetic process (GO:0006241)4.97864849
22response to xenobiotic stimulus (GO:0009410)4.83567461
23otic vesicle formation (GO:0030916)4.76722113
24guanosine-containing compound biosynthetic process (GO:1901070)4.72494869
25polyketide metabolic process (GO:0030638)4.72424518
26doxorubicin metabolic process (GO:0044598)4.72424518
27daunorubicin metabolic process (GO:0044597)4.72424518
28cilium morphogenesis (GO:0060271)4.67155688
29pyrimidine-containing compound transmembrane transport (GO:0072531)4.62030115
30retinal rod cell development (GO:0046548)4.53549568
31microtubule-based movement (GO:0007018)4.50438801
32tolerance induction (GO:0002507)4.46900222
33pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.37420573
34pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.29143597
35retinal cone cell development (GO:0046549)4.14811031
36regulation of interleukin-5 production (GO:0032674)4.11952754
37negative regulation of humoral immune response (GO:0002921)4.11130759
38central nervous system myelination (GO:0022010)4.10331952
39axon ensheathment in central nervous system (GO:0032291)4.10331952
40pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.08899541
41negative regulation of T cell differentiation in thymus (GO:0033085)3.99946523
42lateral ventricle development (GO:0021670)3.95348132
43cytidine catabolic process (GO:0006216)3.95094545
44cytidine deamination (GO:0009972)3.95094545
45cytidine metabolic process (GO:0046087)3.95094545
46regulation of germinal center formation (GO:0002634)3.93288674
47plasma membrane fusion (GO:0045026)3.91749774
48ethanol oxidation (GO:0006069)3.85043447
49terpenoid biosynthetic process (GO:0016114)3.84091907
50multicellular organism reproduction (GO:0032504)3.79091865
51cellular extravasation (GO:0045123)3.78703985
52pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.72684706
53regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.72014727
54retinoic acid metabolic process (GO:0042573)3.71340130
55lung epithelium development (GO:0060428)3.69356533
56exogenous drug catabolic process (GO:0042738)3.68302328
57intra-S DNA damage checkpoint (GO:0031573)3.67514827
58centriole assembly (GO:0098534)3.64854871
59fat-soluble vitamin biosynthetic process (GO:0042362)3.61439257
60sperm capacitation (GO:0048240)3.56076972
61cytoplasmic microtubule organization (GO:0031122)3.54201912
62photoreceptor cell maintenance (GO:0045494)3.52804586
63glomerular epithelial cell development (GO:0072310)3.52171383
64cardiovascular system development (GO:0072358)3.46598768
65DNA deamination (GO:0045006)3.46294373
66sequestering of actin monomers (GO:0042989)3.41335152
67determination of left/right symmetry (GO:0007368)3.35213162
68positive regulation of tolerance induction (GO:0002645)3.29280870
69mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.24937993
70microtubule depolymerization (GO:0007019)3.22694393
71regulation of interleukin-13 production (GO:0032656)3.22592094
72glutathione derivative biosynthetic process (GO:1901687)3.21485069
73glutathione derivative metabolic process (GO:1901685)3.21485069
74determination of bilateral symmetry (GO:0009855)3.20517567
75sperm motility (GO:0030317)3.20464739
76purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.18054548
77import into cell (GO:0098657)3.15543303
78negative regulation of oligodendrocyte differentiation (GO:0048715)3.15119262
79drug catabolic process (GO:0042737)3.14336395
80specification of symmetry (GO:0009799)3.11445920
81purine nucleoside triphosphate biosynthetic process (GO:0009145)3.10889674
82microtubule bundle formation (GO:0001578)3.10856946
83establishment of apical/basal cell polarity (GO:0035089)3.08561836
84one-carbon compound transport (GO:0019755)3.06683557
85positive regulation of astrocyte differentiation (GO:0048711)3.06621150
86muscle organ morphogenesis (GO:0048644)3.05972357
87left/right axis specification (GO:0070986)3.04321055
88retinol metabolic process (GO:0042572)3.03081127
89acrosome assembly (GO:0001675)3.02770316
90protein palmitoylation (GO:0018345)3.00875651
91cilium organization (GO:0044782)3.00746454
92nucleotide phosphorylation (GO:0046939)3.00038592
93microtubule polymerization or depolymerization (GO:0031109)2.99622415
94phenylpropanoid metabolic process (GO:0009698)2.98525075
95O-glycan processing (GO:0016266)2.94966446
96cilium assembly (GO:0042384)2.90754106
97aminoglycoside antibiotic metabolic process (GO:0030647)2.90360368
98centriole replication (GO:0007099)2.89261249
99photoreceptor cell differentiation (GO:0046530)2.88094269
100eye photoreceptor cell differentiation (GO:0001754)2.88094269
101neurotransmitter catabolic process (GO:0042135)2.87446379
102smoothened signaling pathway (GO:0007224)2.87188804
103establishment of tissue polarity (GO:0007164)2.86157045
104establishment of planar polarity (GO:0001736)2.86157045
105nonmotile primary cilium assembly (GO:0035058)2.85036292
106cellular response to epinephrine stimulus (GO:0071872)2.84728317
107ribosomal large subunit biogenesis (GO:0042273)2.84332026
108nucleoside diphosphate metabolic process (GO:0009132)2.84294011
109primary alcohol metabolic process (GO:0034308)2.80992337
110mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.78791663
111negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.78372951
112pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.77133740
113regulation of development, heterochronic (GO:0040034)2.76629983
114establishment or maintenance of monopolar cell polarity (GO:0061339)2.75437570
115establishment of monopolar cell polarity (GO:0061162)2.75437570
116cornea development in camera-type eye (GO:0061303)2.75299060
117cellular component assembly involved in morphogenesis (GO:0010927)2.74319367
118protein polyglutamylation (GO:0018095)2.72516695
119aldehyde catabolic process (GO:0046185)2.71968578
120negative regulation of immunoglobulin mediated immune response (GO:0002890)2.71271923
121negative regulation of B cell mediated immunity (GO:0002713)2.71271923
122pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.70911481
123pyrimidine ribonucleoside metabolic process (GO:0046131)2.70457772
124reproduction (GO:0000003)2.70054790
125intraciliary transport (GO:0042073)2.69516376
126keratinocyte development (GO:0003334)2.67689325
127hydrogen peroxide biosynthetic process (GO:0050665)2.66685136
128electron transport chain (GO:0022900)2.64650127
129respiratory electron transport chain (GO:0022904)2.64293348
130regulation of timing of cell differentiation (GO:0048505)2.64199978
131sperm-egg recognition (GO:0035036)2.64183753
132ribonucleoside triphosphate biosynthetic process (GO:0009201)2.64052749
133ATP synthesis coupled proton transport (GO:0015986)2.63654376
134energy coupled proton transport, down electrochemical gradient (GO:0015985)2.63654376
135cellular response to interleukin-15 (GO:0071350)2.63601408
136organelle assembly (GO:0070925)2.62355294
137negative regulation of inclusion body assembly (GO:0090084)2.62263076
138microtubule-based process (GO:0007017)2.62156704
139negative T cell selection (GO:0043383)2.61611062
140neuron cell-cell adhesion (GO:0007158)2.60737920
141negative thymic T cell selection (GO:0045060)2.58594519
142serotonin receptor signaling pathway (GO:0007210)2.57942155
143positive regulation of smoothened signaling pathway (GO:0045880)2.56092604
144phosphatidylcholine biosynthetic process (GO:0006656)2.55227812
145response to epinephrine (GO:0071871)2.54996932
146lateral sprouting from an epithelium (GO:0060601)2.53429471
147cell projection assembly (GO:0030031)2.53172211
148excretion (GO:0007588)2.53041558
149regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.52878342
150activated T cell proliferation (GO:0050798)2.49480295
151hair follicle development (GO:0001942)2.49056540
152regulation of autophagic vacuole assembly (GO:2000785)2.46696159
153NIK/NF-kappaB signaling (GO:0038061)2.45062222
154pyrimidine ribonucleotide metabolic process (GO:0009218)2.45058449
155Sertoli cell development (GO:0060009)2.44776126
156gas transport (GO:0015669)2.44732712
157regulation of vitamin metabolic process (GO:0030656)2.44705498
158nucleoside triphosphate biosynthetic process (GO:0009142)2.42323261
159pyrimidine nucleoside biosynthetic process (GO:0046134)2.41762330
160negative regulation of cAMP-mediated signaling (GO:0043951)2.38772268
161reactive oxygen species biosynthetic process (GO:1903409)2.36933793
162rRNA catabolic process (GO:0016075)2.35690687
163regulation of tolerance induction (GO:0002643)2.35317511
164calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.34834890
165regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.34774308
166regulation of collateral sprouting (GO:0048670)2.33128472
167benzene-containing compound metabolic process (GO:0042537)2.32388860
168regulation of cilium assembly (GO:1902017)2.31079810
169protein O-linked glycosylation (GO:0006493)2.27385053
170organic cation transport (GO:0015695)2.25115342
171heart looping (GO:0001947)2.23160801
172regulation of interleukin-6 biosynthetic process (GO:0045408)2.20608760
173L-ascorbic acid metabolic process (GO:0019852)2.19083812
174phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.17699538
175axonemal dynein complex assembly (GO:0070286)10.4788945
176cilium or flagellum-dependent cell motility (GO:0001539)10.4567086
177cell wall macromolecule catabolic process (GO:0016998)10.4462224
178cell wall macromolecule metabolic process (GO:0044036)10.4462224

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.89814038
2VDR_22108803_ChIP-Seq_LS180_Human3.02777670
3RBPJ_22232070_ChIP-Seq_NCS_Mouse2.98893716
4EZH2_22144423_ChIP-Seq_EOC_Human2.96465593
5FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.86602666
6CDX2_19796622_ChIP-Seq_MESCs_Mouse2.78722305
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.71763673
8PCGF2_27294783_Chip-Seq_ESCs_Mouse2.40054570
9CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.37259374
10PIAS1_25552417_ChIP-Seq_VCAP_Human2.30740532
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.24897537
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.12780517
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.12260561
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.10055820
15SUZ12_27294783_Chip-Seq_NPCs_Mouse2.05487357
16PCGF2_27294783_Chip-Seq_NPCs_Mouse1.95797717
17NFE2_27457419_Chip-Seq_LIVER_Mouse1.87707694
18IRF1_19129219_ChIP-ChIP_H3396_Human1.87658673
19BMI1_23680149_ChIP-Seq_NPCS_Mouse1.84737090
20AHR_22903824_ChIP-Seq_MCF-7_Human1.82288081
21GBX2_23144817_ChIP-Seq_PC3_Human1.79653571
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.77190427
23EZH2_27294783_Chip-Seq_NPCs_Mouse1.74171462
24ESR1_20079471_ChIP-ChIP_T-47D_Human1.71911818
25ZNF274_21170338_ChIP-Seq_K562_Hela1.69107378
26TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.68246876
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.67732377
28SUZ12_18555785_Chip-Seq_ESCs_Mouse1.65534225
29SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.64828282
30ARNT_22903824_ChIP-Seq_MCF-7_Human1.63903768
31SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.63185039
32EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.60803170
33OCT4_18555785_Chip-Seq_ESCs_Mouse1.57905591
34AR_21572438_ChIP-Seq_LNCaP_Human1.57829175
35AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56739022
36P300_19829295_ChIP-Seq_ESCs_Human1.55751724
37CRX_20693478_ChIP-Seq_RETINA_Mouse1.54853136
38POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.54472307
39TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54472307
40AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.53228352
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.52935515
42SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.52675271
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51824304
44NANOG_18555785_Chip-Seq_ESCs_Mouse1.51217101
45EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.51098957
46TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50883703
47ZFX_18555785_Chip-Seq_ESCs_Mouse1.50831625
48* SMAD4_21799915_ChIP-Seq_A2780_Human1.50687717
49EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.50431154
50P53_22387025_ChIP-Seq_ESCs_Mouse1.50238352
51SUZ12_27294783_Chip-Seq_ESCs_Mouse1.49568642
52TRIM28_21343339_ChIP-Seq_HEK293_Human1.47146442
53JARID2_20064375_ChIP-Seq_MESCs_Mouse1.46696209
54E2F1_18555785_Chip-Seq_ESCs_Mouse1.46502263
55TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.46499403
56TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45910936
57STAT3_23295773_ChIP-Seq_U87_Human1.45505408
58SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.44573362
59ETV1_20927104_ChIP-Seq_GIST48_Human1.44220302
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44196908
61EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.44096558
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43275601
63CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43166211
64CMYC_18555785_Chip-Seq_ESCs_Mouse1.42516282
65ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.41531277
66P300_18555785_Chip-Seq_ESCs_Mouse1.41183652
67SOX2_18555785_Chip-Seq_ESCs_Mouse1.41082525
68SMRT_27268052_Chip-Seq_Bcells_Human1.40815459
69FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.40211548
70MTF2_20144788_ChIP-Seq_MESCs_Mouse1.40193425
71TP63_23658742_ChIP-Seq_EP156T_Human1.39986559
72NMYC_18555785_Chip-Seq_ESCs_Mouse1.39394380
73REST_21632747_ChIP-Seq_MESCs_Mouse1.38209187
74STAT3_18555785_Chip-Seq_ESCs_Mouse1.38119909
75SMAD1_18555785_Chip-Seq_ESCs_Mouse1.37927953
76* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.37356107
77IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.36806284
78LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36642896
79FOXA1_27270436_Chip-Seq_PROSTATE_Human1.36514175
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.36514175
81PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.34952837
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.34681762
83KLF4_18555785_Chip-Seq_ESCs_Mouse1.34440046
84SMAD3_21741376_ChIP-Seq_EPCs_Human1.33823888
85LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33725226
86SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.33680219
87TAL1_26923725_Chip-Seq_HPCs_Mouse1.33275667
88JARID2_20075857_ChIP-Seq_MESCs_Mouse1.33150051
89TCF4_23295773_ChIP-Seq_U87_Human1.32023307
90OCT4_21477851_ChIP-Seq_ESCs_Mouse1.31568452
91TP63_17297297_ChIP-ChIP_HaCaT_Human1.31397384
92KAP1_22055183_ChIP-Seq_ESCs_Mouse1.31333389
93PHF8_20622853_ChIP-Seq_HELA_Human1.30396700
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.30161705
95* TCF4_22108803_ChIP-Seq_LS180_Human1.29069294
96PU1_27457419_Chip-Seq_LIVER_Mouse1.28710643
97SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.27931737
98EZH2_18974828_ChIP-Seq_MESCs_Mouse1.27035216
99RNF2_18974828_ChIP-Seq_MESCs_Mouse1.27035216
100STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.26346689
101SMAD4_21741376_ChIP-Seq_EPCs_Human1.25861901
102ER_23166858_ChIP-Seq_MCF-7_Human1.25202530
103SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.24905473
104CTCF_18555785_Chip-Seq_ESCs_Mouse1.24878408
105FOXA1_25552417_ChIP-Seq_VCAP_Human1.24878086
106CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24748637
107UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24638316
108BCAT_22108803_ChIP-Seq_LS180_Human1.24444213
109HNFA_21074721_ChIP-Seq_CACO-2_Human1.23353491
110ESRRB_18555785_Chip-Seq_ESCs_Mouse1.22702954
111MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.22652587
112CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.22348435
113TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.21190927
114RBPJ_21746931_ChIP-Seq_IB4_Human1.21021959
115* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20596572
116AR_20517297_ChIP-Seq_VCAP_Human1.19643819
117KDM2B_26808549_Chip-Seq_REH_Human1.19512652
118TP53_18474530_ChIP-ChIP_U2OS_Human1.18944553
119FOXA1_21572438_ChIP-Seq_LNCaP_Human1.17791954
120POU3F2_20337985_ChIP-ChIP_501MEL_Human1.15557605
121PRDM14_20953172_ChIP-Seq_ESCs_Human1.15422673
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14484676
123RNF2_27304074_Chip-Seq_ESCs_Mouse1.14316111
124TBL1_22424771_ChIP-Seq_293T_Human1.14052310
125NFYA_21822215_ChIP-Seq_K562_Human1.13948266
126BP1_19119308_ChIP-ChIP_Hs578T_Human1.13944697
127Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.13939328
128FUS_26573619_Chip-Seq_HEK293_Human1.13616550
129EWS_26573619_Chip-Seq_HEK293_Human1.13527732
130NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13146030
131NFYB_21822215_ChIP-Seq_K562_Human1.13136731
132TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.12802225
133RUNX1_27457419_Chip-Seq_LIVER_Mouse1.12611565
134STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.12358039
135CBX2_22325352_ChIP-Seq_293T-Rex_Human1.12127092
136RUNX2_22187159_ChIP-Seq_PCA_Human1.12018805
137WDR5_24793694_ChIP-Seq_LNCAP_Human1.11792816
138AR_25329375_ChIP-Seq_VCAP_Human1.11773473
139STAT1_20625510_ChIP-Seq_HELA_Human1.11121973
140CBP_20019798_ChIP-Seq_JUKART_Human1.11025256
141IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11025256
142* CDX2_22108803_ChIP-Seq_LS180_Human1.10838279
143FOXM1_26456572_ChIP-Seq_MCF-7_Human1.10739525
144TAF15_26573619_Chip-Seq_HEK293_Human1.10508883
145NANOG_19829295_ChIP-Seq_ESCs_Human1.09866827
146SOX2_19829295_ChIP-Seq_ESCs_Human1.09866827
147SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09481805
148CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09416481
149STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.09304305
150TP53_16413492_ChIP-PET_HCT116_Human1.08783562
151DROSHA_22980978_ChIP-Seq_HELA_Human1.08504611
152TDRD3_21172665_ChIP-Seq_MCF-7_Human1.08394328
153CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07270642
154IGF1R_20145208_ChIP-Seq_DFB_Human1.07047773
155BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.05461218
156GATA6_21074721_ChIP-Seq_CACO-2_Human1.05115085
157GATA4_25053715_ChIP-Seq_YYC3_Human1.02579937
158GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.02424749
159CEBPB_22108803_ChIP-Seq_LS180_Human1.01831410
160KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99910903
161SMAD3_21741376_ChIP-Seq_HESCs_Human0.99384544

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.56700340
2MP0002653_abnormal_ependyma_morphology6.14969712
3MP0003136_yellow_coat_color4.42421979
4MP0008004_abnormal_stomach_pH3.99907004
5MP0004043_abnormal_pH_regulation3.85162207
6MP0004510_myositis3.56991126
7MP0009780_abnormal_chondrocyte_physiolo3.48844340
8MP0004133_heterotaxia2.90564365
9MP0001485_abnormal_pinna_reflex2.89609679
10MP0009046_muscle_twitch2.86509840
11MP0006292_abnormal_olfactory_placode2.67688226
12MP0004381_abnormal_hair_follicle2.60365837
13MP0008789_abnormal_olfactory_epithelium2.52466690
14MP0004742_abnormal_vestibular_system2.51604872
15MP0002928_abnormal_bile_duct2.50682094
16MP0005379_endocrine/exocrine_gland_phen2.46172960
17MP0002132_abnormal_respiratory_system2.35671347
18MP0002876_abnormal_thyroid_physiology2.35474414
19MP0010678_abnormal_skin_adnexa2.34517413
20MP0003880_abnormal_central_pattern2.16857596
21MP0003878_abnormal_ear_physiology2.14100256
22MP0005377_hearing/vestibular/ear_phenot2.14100256
23MP0005253_abnormal_eye_physiology2.06791152
24MP0005671_abnormal_response_to2.06010139
25MP0002736_abnormal_nociception_after1.99362959
26MP0002277_abnormal_respiratory_mucosa1.97778869
27MP0004019_abnormal_vitamin_homeostasis1.97266836
28MP0002735_abnormal_chemical_nociception1.94494395
29MP0001835_abnormal_antigen_presentation1.93179770
30MP0002163_abnormal_gland_morphology1.91508898
31MP0002168_other_aberrant_phenotype1.90354018
32MP0006276_abnormal_autonomic_nervous1.87764226
33MP0005551_abnormal_eye_electrophysiolog1.79679468
34MP0001968_abnormal_touch/_nociception1.79642510
35MP0003724_increased_susceptibility_to1.76925234
36MP0009697_abnormal_copulation1.74565019
37MP0005310_abnormal_salivary_gland1.72856370
38MP0001765_abnormal_ion_homeostasis1.69782835
39MP0001346_abnormal_lacrimal_gland1.66932979
40MP0003195_calcinosis1.64921648
41MP0010386_abnormal_urinary_bladder1.62853436
42MP0002166_altered_tumor_susceptibility1.60896789
43MP0002249_abnormal_larynx_morphology1.60847069
44MP0001348_abnormal_lacrimal_gland1.57638200
45MP0005083_abnormal_biliary_tract1.53388957
46MP0008872_abnormal_physiological_respon1.53157201
47MP0002102_abnormal_ear_morphology1.50876947
48MP0005410_abnormal_fertilization1.48629635
49MP0002138_abnormal_hepatobiliary_system1.47519631
50MP0003656_abnormal_erythrocyte_physiolo1.41168384
51MP0003763_abnormal_thymus_physiology1.40341365
52MP0003879_abnormal_hair_cell1.40339684
53MP0002006_tumorigenesis1.35710814
54MP0000383_abnormal_hair_follicle1.35693531
55MP0005645_abnormal_hypothalamus_physiol1.33061680
56MP0002282_abnormal_trachea_morphology1.32368857
57MP0005395_other_phenotype1.31726745
58MP0005636_abnormal_mineral_homeostasis1.31581126
59MP0001661_extended_life_span1.28113659
60MP0005623_abnormal_meninges_morphology1.27540921
61MP0005499_abnormal_olfactory_system1.27427008
62MP0005394_taste/olfaction_phenotype1.27427008
63MP0004142_abnormal_muscle_tone1.27235824
64MP0003690_abnormal_glial_cell1.25802877
65MP0001790_abnormal_immune_system1.25350850
66MP0005387_immune_system_phenotype1.25350850
67MP0002095_abnormal_skin_pigmentation1.25306356
68MP0002557_abnormal_social/conspecific_i1.24682302
69MP0002909_abnormal_adrenal_gland1.23121698
70MP0002405_respiratory_system_inflammati1.22944915
71MP0009745_abnormal_behavioral_response1.22928251
72MP0004858_abnormal_nervous_system1.21920404
73MP0001986_abnormal_taste_sensitivity1.20268557
74MP0005646_abnormal_pituitary_gland1.18179041
75MP0003633_abnormal_nervous_system1.18096405
76MP0001440_abnormal_grooming_behavior1.16665402
77MP0000566_synostosis1.16662445
78MP0000579_abnormal_nail_morphology1.15660605
79MP0005389_reproductive_system_phenotype1.14555568
80MP0001529_abnormal_vocalization1.13947577
81MP0008995_early_reproductive_senescence1.12816469
82MP0002734_abnormal_mechanical_nocicepti1.12735901
83MP0010155_abnormal_intestine_physiology1.11499930
84MP0002254_reproductive_system_inflammat1.09216301
85MP0001851_eye_inflammation1.08634807
86MP0003950_abnormal_plasma_membrane1.07715388
87MP0001970_abnormal_pain_threshold1.07044221
88MP0001963_abnormal_hearing_physiology1.06718031
89MP0001800_abnormal_humoral_immune1.05403787
90MP0000026_abnormal_inner_ear1.05067216
91MP0005000_abnormal_immune_tolerance1.04602025
92MP0004484_altered_response_of1.04358005
93MP0002638_abnormal_pupillary_reflex1.02751373
94MP0009764_decreased_sensitivity_to1.02668111
95MP0001984_abnormal_olfaction1.02303080
96MP0002723_abnormal_immune_serum1.01299373
97MP0002064_seizures1.01122865
98MP0005365_abnormal_bile_salt0.97902638
99MP0003186_abnormal_redox_activity0.97277910
100MP0002233_abnormal_nose_morphology0.96986461
101MP0009643_abnormal_urine_homeostasis0.96689148
102MP0003635_abnormal_synaptic_transmissio0.96417942
103MP0000920_abnormal_myelination0.95998404
104MP0000631_abnormal_neuroendocrine_gland0.92244933
105MP0005025_abnormal_response_to0.91556249
106MP0005084_abnormal_gallbladder_morpholo0.90388189
107MP0002148_abnormal_hypersensitivity_rea0.89947517
108MP0005220_abnormal_exocrine_pancreas0.89937863
109MP0001929_abnormal_gametogenesis0.88637762
110MP0003698_abnormal_male_reproductive0.88393523
111MP0002572_abnormal_emotion/affect_behav0.88187338
112MP0003634_abnormal_glial_cell0.87738684
113MP0000465_gastrointestinal_hemorrhage0.87404938
114MP0000470_abnormal_stomach_morphology0.87148029
115MP0002136_abnormal_kidney_physiology0.87071444
116MP0001486_abnormal_startle_reflex0.86810234
117MP0000613_abnormal_salivary_gland0.86220811
118MP0004782_abnormal_surfactant_physiolog0.85540235
119MP0003787_abnormal_imprinting0.85514980
120MP0008569_lethality_at_weaning0.85227666
121MP0000462_abnormal_digestive_system0.84850157
122MP0005195_abnormal_posterior_eye0.84656837
123MP0000747_muscle_weakness0.82766549
124MP0002229_neurodegeneration0.82159848
125MP0005408_hypopigmentation0.81974825
126MP0003938_abnormal_ear_development0.81863954
127MP0001502_abnormal_circadian_rhythm0.80369984
128MP0002938_white_spotting0.78394903
129MP0005248_abnormal_Harderian_gland0.78152963
130MP0000427_abnormal_hair_cycle0.77563921
131MP0005391_vision/eye_phenotype0.77169821
132MP0002733_abnormal_thermal_nociception0.77123425
133MP0002160_abnormal_reproductive_system0.76812266
134MP0002837_dystrophic_cardiac_calcinosis0.76446107
135MP0001944_abnormal_pancreas_morphology0.75124724
136MP0004885_abnormal_endolymph0.75097214
137MP0002452_abnormal_antigen_presenting0.74229641
138MP0001819_abnormal_immune_cell0.74027977
139MP0003075_altered_response_to0.73665772
140MP0002420_abnormal_adaptive_immunity0.73034677
141MP0005165_increased_susceptibility_to0.72844640
142MP0004215_abnormal_myocardial_fiber0.72700690
143MP0005085_abnormal_gallbladder_physiolo0.72161702
144MP0000751_myopathy0.71105425
145MP0001324_abnormal_eye_pigmentation0.70933047
146MP0000681_abnormal_thyroid_gland0.69044913
147MP0005535_abnormal_body_temperature0.68074544
148MP0003011_delayed_dark_adaptation0.65627203
149MP0003866_abnormal_defecation0.64413591
150MP0003045_fibrosis0.61386911
151MP0006082_CNS_inflammation0.60270229
152MP0003718_maternal_effect0.60249229
153MP0006072_abnormal_retinal_apoptosis0.57751013
154MP0009765_abnormal_xenobiotic_induced0.55899837
155MP0010234_abnormal_vibrissa_follicle0.53418533
156MP0001756_abnormal_urination0.52972806
157MP0001270_distended_abdomen0.51444246
158MP0001664_abnormal_digestion0.51330933
159MP0002693_abnormal_pancreas_physiology0.51290263
160MP0006036_abnormal_mitochondrial_physio0.50821004
161MP0005187_abnormal_penis_morphology0.50560159
162MP0009763_increased_sensitivity_to0.49367368
163MP0008873_increased_physiological_sensi0.49281803

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.60630293
2Rhinitis (HP:0012384)8.92247898
3Abnormal respiratory motile cilium morphology (HP:0005938)8.92189290
4Abnormal respiratory epithelium morphology (HP:0012253)8.92189290
5Absent/shortened dynein arms (HP:0200106)7.32734259
6Dynein arm defect of respiratory motile cilia (HP:0012255)7.32734259
7Chronic bronchitis (HP:0004469)6.10689647
8Bronchiectasis (HP:0002110)5.30473633
9Chronic sinusitis (HP:0011109)4.34761050
10Nasal polyposis (HP:0100582)4.24979416
11Recurrent sinusitis (HP:0011108)3.98697404
12Chronic otitis media (HP:0000389)3.78018382
13Bronchitis (HP:0012387)3.74030167
14Abnormality of the nasal mucosa (HP:0000433)3.53743351
15Occipital encephalocele (HP:0002085)3.42484729
16Chronic hepatic failure (HP:0100626)3.42024563
17Follicular hyperkeratosis (HP:0007502)3.39036424
18Male infertility (HP:0003251)3.20873975
19Ventricular fibrillation (HP:0001663)3.16066940
20Tubulointerstitial nephritis (HP:0001970)3.15448319
21Cystic liver disease (HP:0006706)2.95492009
22Recurrent otitis media (HP:0000403)2.91795784
23Hyperactive renin-angiotensin system (HP:0000841)2.84787906
24Absent rod-and cone-mediated responses on ERG (HP:0007688)2.77768004
25Pili torti (HP:0003777)2.76023539
26Abnormality of the renal medulla (HP:0100957)2.75518140
27Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.72881837
28Degeneration of the lateral corticospinal tracts (HP:0002314)2.72881837
29Gait imbalance (HP:0002141)2.61873970
303-Methylglutaconic aciduria (HP:0003535)2.48421089
31Congenital primary aphakia (HP:0007707)2.48335443
32Thin bony cortex (HP:0002753)2.40521346
33Termporal pattern (HP:0011008)2.39830244
34Insidious onset (HP:0003587)2.39830244
35Elevated erythrocyte sedimentation rate (HP:0003565)2.36387463
36Pancreatic fibrosis (HP:0100732)2.35882498
37Enlarged epiphyses (HP:0010580)2.31429481
38Congenital, generalized hypertrichosis (HP:0004540)2.31198578
39Congenital hepatic fibrosis (HP:0002612)2.29274893
40Atelectasis (HP:0100750)2.26519655
41Axonal loss (HP:0003447)2.25480806
42Medial flaring of the eyebrow (HP:0010747)2.24332199
43Abnormality of abdominal situs (HP:0011620)2.23368957
44Abdominal situs inversus (HP:0003363)2.23368957
45Genital tract atresia (HP:0001827)2.22389264
46Bile duct proliferation (HP:0001408)2.21593932
47Abnormal biliary tract physiology (HP:0012439)2.21593932
48True hermaphroditism (HP:0010459)2.19607870
49Abnormal rod and cone electroretinograms (HP:0008323)2.18855687
50Recurrent bronchitis (HP:0002837)2.16257180
51Median cleft lip (HP:0000161)2.15859140
52Type 2 muscle fiber atrophy (HP:0003554)2.15777275
53Decreased circulating renin level (HP:0003351)2.14438974
54Nephrogenic diabetes insipidus (HP:0009806)2.11826700
55Anencephaly (HP:0002323)2.10418210
56Abnormality of the corticospinal tract (HP:0002492)2.09715316
57Aplasia/Hypoplasia of the tongue (HP:0010295)2.09340691
58Acute necrotizing encephalopathy (HP:0006965)2.03154426
59Progressive macrocephaly (HP:0004481)2.02738467
60Infertility (HP:0000789)2.00252275
61Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.3896049
62Abnormal respiratory motile cilium physiology (HP:0012261)10.2025512
63Male pseudohermaphroditism (HP:0000037)1.98449337
64Vaginal atresia (HP:0000148)1.92679729
65Furrowed tongue (HP:0000221)1.91056680
66Ridged nail (HP:0001807)1.90836298
67Asplenia (HP:0001746)1.89387309
68Supernumerary spleens (HP:0009799)1.89055737
69Aplasia/Hypoplasia of the spleen (HP:0010451)1.88900201
70Delayed epiphyseal ossification (HP:0002663)1.88588337
71Muscle fiber atrophy (HP:0100295)1.85702965
72Sclerocornea (HP:0000647)1.80796241
73Renal salt wasting (HP:0000127)1.79048338
74Metaphyseal dysplasia (HP:0100255)1.76355728
75Cone-rod dystrophy (HP:0000548)1.74648848
76Oculomotor apraxia (HP:0000657)1.73362912
77Postaxial hand polydactyly (HP:0001162)1.72574334
78Nephropathy (HP:0000112)1.71335143
79Chronic mucocutaneous candidiasis (HP:0002728)1.68031386
80Recurrent cutaneous fungal infections (HP:0011370)1.68031386
81Abnormal mitochondria in muscle tissue (HP:0008316)1.67369014
82Decreased central vision (HP:0007663)1.67283178
83Sparse eyelashes (HP:0000653)1.66214914
84Abnormality of the renal cortex (HP:0011035)1.65840084
85Bell-shaped thorax (HP:0001591)1.63251311
86Hyperkalemia (HP:0002153)1.62927337
87Fatigable weakness (HP:0003473)1.62579733
88Abnormality of the neuromuscular junction (HP:0003398)1.62579733
89Hyperaldosteronism (HP:0000859)1.61513073
90Glossoptosis (HP:0000162)1.60487352
91Acute encephalopathy (HP:0006846)1.60454086
92Amniotic constriction ring (HP:0009775)1.59833409
93Abnormality of placental membranes (HP:0011409)1.59833409
94Pustule (HP:0200039)1.59790518
95Hypomagnesemia (HP:0002917)1.59621578
96Weak cry (HP:0001612)1.58230054
97Severe combined immunodeficiency (HP:0004430)1.58151065
98Poor coordination (HP:0002370)1.56648430
99Tubulointerstitial abnormality (HP:0001969)1.55366904
100Congenital sensorineural hearing impairment (HP:0008527)1.55178397
101Tibial bowing (HP:0002982)1.54829569
102Polydipsia (HP:0001959)1.54542240
103Abnormal drinking behavior (HP:0030082)1.54542240
104Widely patent fontanelles and sutures (HP:0004492)1.53426648
105Absent frontal sinuses (HP:0002688)1.53349632
106Abnormality of renin-angiotensin system (HP:0000847)1.52851762
107Aplasia/Hypoplasia of the lens (HP:0008063)1.51928976
108Unilateral renal agenesis (HP:0000122)1.51800438
109Flat occiput (HP:0005469)1.51650480
110Mitochondrial inheritance (HP:0001427)1.51385548
111Fair hair (HP:0002286)1.50308500
112Increased IgM level (HP:0003496)1.49508837
113Hypokalemic alkalosis (HP:0001949)1.49416651
11411 pairs of ribs (HP:0000878)1.49367415
115Abnormal hair laboratory examination (HP:0003328)1.47978213
116Abnormality of midbrain morphology (HP:0002418)1.47965617
117Molar tooth sign on MRI (HP:0002419)1.47965617
118Neonatal short-limb short stature (HP:0008921)1.47060942
119Sex reversal (HP:0012245)1.46515365
120Abnormal sex determination (HP:0012244)1.46515365
121Bronchomalacia (HP:0002780)1.46252707
122Nephronophthisis (HP:0000090)1.44006851
123Poikiloderma (HP:0001029)1.43633768
124Cheilitis (HP:0100825)1.43433996
125Pancreatic cysts (HP:0001737)1.42829397
126Decreased muscle mass (HP:0003199)1.42729240
127Abnormality of macular pigmentation (HP:0008002)1.42431339
128Abnormal EKG (HP:0003115)1.41484981
129Exercise intolerance (HP:0003546)1.39244564
130Tubular atrophy (HP:0000092)1.38486640
131Stage 5 chronic kidney disease (HP:0003774)1.38157375
132Postaxial foot polydactyly (HP:0001830)1.37436428
133Bony spicule pigmentary retinopathy (HP:0007737)1.36910432
134Eczematoid dermatitis (HP:0000976)1.36330963
135Abnormality of chloride homeostasis (HP:0011422)1.36299306
136Preaxial hand polydactyly (HP:0001177)1.36103196
137Retinitis pigmentosa (HP:0000510)1.34680948
138Prolonged QT interval (HP:0001657)1.31965494
139Metaphyseal irregularity (HP:0003025)1.31010671
140Constricted visual fields (HP:0001133)1.26006635
141Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.17054631
142Short thorax (HP:0010306)1.15279246
143Abolished electroretinogram (ERG) (HP:0000550)1.10482624
144Tubulointerstitial fibrosis (HP:0005576)1.07615283
145Hyponatremia (HP:0002902)1.06722585
146Hip dysplasia (HP:0001385)1.05511477
147Polyuria (HP:0000103)1.03720148
148Abnormality of the frontal sinuses (HP:0002687)1.02094033
149Abnormality of renal excretion (HP:0011036)1.01924825
150Absent speech (HP:0001344)1.01522275
151Narrow forehead (HP:0000341)1.01299781
152Alveolar cell carcinoma (HP:0006519)1.00894725
153Prominent nasal bridge (HP:0000426)0.99985483
154Disproportionate short-trunk short stature (HP:0003521)0.99498512
155Multicystic kidney dysplasia (HP:0000003)0.98798201
156Aganglionic megacolon (HP:0002251)0.98559272
157Portal hypertension (HP:0001409)0.98294407
158Abnormality of the dental pulp (HP:0006479)0.97552617
159Abnormality of permanent molar morphology (HP:0011071)0.97047589
160Taurodontia (HP:0000679)0.97047589

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.72774383
2MAP3K124.05463744
3MST43.95624108
4PBK3.91104023
5MAP4K13.45482951
6TXK3.09509821
7MAPKAPK32.45396998
8NME12.26469621
9DAPK22.18318734
10ZAK2.14044217
11STK391.91494727
12TESK21.91438754
13IRAK21.78661925
14PTK2B1.77464176
15MYLK1.75156202
16STK101.70018538
17BCR1.59457765
18KDR1.57413908
19STK241.56046910
20IRAK31.55492734
21IKBKE1.52547558
22PRKCH1.46697799
23ADRBK21.46144620
24BLK1.45459758
25ACVR1B1.44178292
26EPHA31.37687780
27JAK11.36779119
28OXSR11.33180836
29LIMK11.30527529
30CDK191.29789867
31CSK1.25252721
32STK31.22487522
33STK38L1.12639879
34FGFR21.07499937
35ITK1.05803800
36TTK1.05247354
37STK161.04443982
38WNK31.01399738
39ERBB20.99854391
40PRKCI0.97940541
41FGFR40.96606830
42ROCK20.95533572
43LRRK20.95287507
44TEC0.95137329
45SCYL20.94430867
46BRSK20.94371223
47PAK30.92980730
48ADRBK10.92738160
49RIPK10.92072247
50TLK10.91749138
51INSRR0.91135667
52ERBB30.90368394
53TYRO30.90110716
54NEK60.89959832
55MAP3K30.88045157
56SYK0.86739929
57PRKCQ0.86624763
58PRKD30.86481778
59PIK3CG0.86077365
60WNK10.85729569
61MAP3K20.83456926
62LCK0.82840051
63MAP3K70.80788697
64MAPK130.80659402
65FER0.79736145
66MARK20.79691268
67PRKD20.75882989
68TBK10.74309923
69MAP3K110.74219546
70EPHB10.73898062
71TRPM70.70776795
72GRK10.70221275
73MELK0.69345590
74MAP3K140.69342746
75MAPK150.68278259
76FYN0.68068746
77STK380.68001267
78GRK60.67825799
79IRAK10.67791828
80PIM20.67034737
81LYN0.63544943
82JAK20.63387688
83PKN10.62375739
84NLK0.60352262
85GRK50.59522251
86PINK10.59387785
87ROCK10.59302143
88ZAP700.58443125
89MAPKAPK50.57480365
90PRKAA20.56700629
91FES0.56594981
92MKNK20.55547949
93BMPR1B0.55143945
94SGK20.55082124
95NTRK20.55062459
96SIK30.53995487
97FGFR30.53869913
98MAP4K20.52616070
99PRKCE0.52318451
100IKBKB0.52138292
101CLK10.51774951
102PHKG20.51431077
103PHKG10.51431077
104PRKCA0.50853997
105CASK0.48123041
106PRKCD0.47460389
107RIPK40.45889086
108WNK40.45629447
109CAMK2A0.45509166
110CDK150.45380528
111CDK180.45345718
112PNCK0.45289228
113CAMKK20.45255820
114TESK10.44812680
115EIF2AK20.43560092
116ABL10.43127959
117PRKD10.42367515
118EGFR0.41268658
119STK110.41232215
120HIPK20.41014243
121EPHA20.40968399
122PRKCG0.40359142
123AURKA0.40061827
124CDK140.40024392
125CSNK1G10.38968500
126CDK11A0.37810935
127ABL20.37792020
128LMTK20.37496903
129PRKACA0.37389617
130SGK10.37112105
131IGF1R0.37109994
132NUAK10.36919617
133TGFBR20.36865913
134MUSK0.36340578
135MAP3K40.36237767
136TYK20.36075389
137TGFBR10.33257035
138SGK2230.30949241
139SGK4940.30949241
140PRKG10.28454629
141CAMK2G0.25690603
142MST1R0.24521079
143KIT0.24036831
144MAP2K20.22737051
145DYRK1A0.22648479
146TRIM280.21112222
147BTK0.20470848
148MAP2K70.20130500
149EEF2K0.19844648
150CAMKK10.19721770
151CHUK0.19318236
152EIF2AK30.19018804

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.12170721
2Caffeine metabolism_Homo sapiens_hsa002323.21345237
3Oxidative phosphorylation_Homo sapiens_hsa001903.18842011
4Huntingtons disease_Homo sapiens_hsa050163.11899782
5Phenylalanine metabolism_Homo sapiens_hsa003603.10667726
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.06320881
7Linoleic acid metabolism_Homo sapiens_hsa005912.82447099
8Tyrosine metabolism_Homo sapiens_hsa003502.66429720
9Parkinsons disease_Homo sapiens_hsa050122.60491473
10Primary immunodeficiency_Homo sapiens_hsa053402.56621914
11Alzheimers disease_Homo sapiens_hsa050102.35781450
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.34907133
13Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.30587683
14Cell adhesion molecules (CAMs)_Homo sapiens_hsa045142.06396643
15ABC transporters_Homo sapiens_hsa020102.05258379
16Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.04041454
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93743201
18Pentose phosphate pathway_Homo sapiens_hsa000301.91041717
19Proteasome_Homo sapiens_hsa030501.77827249
20Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.76840869
21Autoimmune thyroid disease_Homo sapiens_hsa053201.74469274
22Cardiac muscle contraction_Homo sapiens_hsa042601.71196074
23Steroid hormone biosynthesis_Homo sapiens_hsa001401.68433504
24Nicotine addiction_Homo sapiens_hsa050331.61990077
25Salivary secretion_Homo sapiens_hsa049701.50311816
26Ribosome_Homo sapiens_hsa030101.48422379
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.44974810
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40488294
29Ether lipid metabolism_Homo sapiens_hsa005651.38677376
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.34736894
31Circadian rhythm_Homo sapiens_hsa047101.33543778
32alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32151280
33PPAR signaling pathway_Homo sapiens_hsa033201.30657918
34Gastric acid secretion_Homo sapiens_hsa049711.30431624
35Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.29258191
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.27475364
37Sphingolipid metabolism_Homo sapiens_hsa006001.26139618
38Morphine addiction_Homo sapiens_hsa050321.25527206
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.25207678
40Allograft rejection_Homo sapiens_hsa053301.21415869
41Jak-STAT signaling pathway_Homo sapiens_hsa046301.20461472
42Staphylococcus aureus infection_Homo sapiens_hsa051501.20323779
43Butanoate metabolism_Homo sapiens_hsa006501.18362514
44Primary bile acid biosynthesis_Homo sapiens_hsa001201.13029022
45GABAergic synapse_Homo sapiens_hsa047271.12141780
46Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11916803
47Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.06169119
48Propanoate metabolism_Homo sapiens_hsa006401.02587409
49Type I diabetes mellitus_Homo sapiens_hsa049401.02569069
50Hematopoietic cell lineage_Homo sapiens_hsa046401.01580595
51Fatty acid degradation_Homo sapiens_hsa000711.00667376
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00586595
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99101594
54Histidine metabolism_Homo sapiens_hsa003400.98965588
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.98210159
56Retinol metabolism_Homo sapiens_hsa008300.97498396
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96764469
58Pentose and glucuronate interconversions_Homo sapiens_hsa000400.96418972
59Serotonergic synapse_Homo sapiens_hsa047260.96104726
60Taste transduction_Homo sapiens_hsa047420.94865890
61Collecting duct acid secretion_Homo sapiens_hsa049660.90840337
62T cell receptor signaling pathway_Homo sapiens_hsa046600.90658806
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.90309773
64Viral myocarditis_Homo sapiens_hsa054160.89417429
65Calcium signaling pathway_Homo sapiens_hsa040200.89131212
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.88870716
67Glutamatergic synapse_Homo sapiens_hsa047240.88134826
68Tryptophan metabolism_Homo sapiens_hsa003800.86166689
69Glutathione metabolism_Homo sapiens_hsa004800.78210791
70Nitrogen metabolism_Homo sapiens_hsa009100.77861715
71Fatty acid elongation_Homo sapiens_hsa000620.74981057
72Asthma_Homo sapiens_hsa053100.74784416
73Chemical carcinogenesis_Homo sapiens_hsa052040.73258356
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.73056338
75Regulation of autophagy_Homo sapiens_hsa041400.72847243
76Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.72246634
77Starch and sucrose metabolism_Homo sapiens_hsa005000.72217911
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.71551284
79Measles_Homo sapiens_hsa051620.70582694
80Insulin secretion_Homo sapiens_hsa049110.70386502
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.69624762
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67675040
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.65881187
84Peroxisome_Homo sapiens_hsa041460.65138811
85Mineral absorption_Homo sapiens_hsa049780.65071989
86Protein digestion and absorption_Homo sapiens_hsa049740.64408235
87Non-homologous end-joining_Homo sapiens_hsa034500.63869652
88Graft-versus-host disease_Homo sapiens_hsa053320.63643390
89Olfactory transduction_Homo sapiens_hsa047400.63620255
90Systemic lupus erythematosus_Homo sapiens_hsa053220.63030829
91Cholinergic synapse_Homo sapiens_hsa047250.62690749
92Glycerolipid metabolism_Homo sapiens_hsa005610.62623637
93Vitamin digestion and absorption_Homo sapiens_hsa049770.62244311
94Circadian entrainment_Homo sapiens_hsa047130.62146195
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60802487
96Renin-angiotensin system_Homo sapiens_hsa046140.60199677
97cAMP signaling pathway_Homo sapiens_hsa040240.57383959
98Amphetamine addiction_Homo sapiens_hsa050310.57299876
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.56513689
100Steroid biosynthesis_Homo sapiens_hsa001000.55911968
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55538109
102Complement and coagulation cascades_Homo sapiens_hsa046100.55524029
103Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55137058
104Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.54999491
105Dopaminergic synapse_Homo sapiens_hsa047280.54988003
106Rap1 signaling pathway_Homo sapiens_hsa040150.54556350
107NF-kappa B signaling pathway_Homo sapiens_hsa040640.54038443
108Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.52954937
109Hedgehog signaling pathway_Homo sapiens_hsa043400.51884594
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49285903
111Cocaine addiction_Homo sapiens_hsa050300.48618700
112Dorso-ventral axis formation_Homo sapiens_hsa043200.48256975
113Melanogenesis_Homo sapiens_hsa049160.47006216
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.46918435
115Tight junction_Homo sapiens_hsa045300.46426312
116Pancreatic secretion_Homo sapiens_hsa049720.44991825
117Selenocompound metabolism_Homo sapiens_hsa004500.43697209
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.43437627
119Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42579411
120Folate biosynthesis_Homo sapiens_hsa007900.42351631
121Vascular smooth muscle contraction_Homo sapiens_hsa042700.41997011
122Hippo signaling pathway_Homo sapiens_hsa043900.39318120
123Antigen processing and presentation_Homo sapiens_hsa046120.38439828
124Thyroid hormone synthesis_Homo sapiens_hsa049180.38368144
125Arachidonic acid metabolism_Homo sapiens_hsa005900.35999175
126Metabolic pathways_Homo sapiens_hsa011000.35676100
127Phototransduction_Homo sapiens_hsa047440.34481418
128Purine metabolism_Homo sapiens_hsa002300.34379659
129Protein export_Homo sapiens_hsa030600.33935283
130Pertussis_Homo sapiens_hsa051330.33489205
131Rheumatoid arthritis_Homo sapiens_hsa053230.33238790
132Ovarian steroidogenesis_Homo sapiens_hsa049130.31818770
133Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31318723
134beta-Alanine metabolism_Homo sapiens_hsa004100.31008411
135Salmonella infection_Homo sapiens_hsa051320.30864683
136Renin secretion_Homo sapiens_hsa049240.30100149
137Choline metabolism in cancer_Homo sapiens_hsa052310.29979668
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29799990
139Transcriptional misregulation in cancer_Homo sapiens_hsa052020.28623758
140Sphingolipid signaling pathway_Homo sapiens_hsa040710.28447809
141Hepatitis C_Homo sapiens_hsa051600.23205251
142Basal cell carcinoma_Homo sapiens_hsa052170.21146704
143Legionellosis_Homo sapiens_hsa051340.19937405

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