

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.79552875 |
| 2 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.45464153 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.23412173 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.23412173 |
| 5 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.18745023 |
| 6 | NADH dehydrogenase complex assembly (GO:0010257) | 4.18745023 |
| 7 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.18745023 |
| 8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.15826203 |
| 9 | proteasome assembly (GO:0043248) | 4.09520614 |
| 10 | protein complex biogenesis (GO:0070271) | 4.07544655 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 3.95910723 |
| 12 | cullin deneddylation (GO:0010388) | 3.83744169 |
| 13 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.82625225 |
| 14 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.81410213 |
| 15 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.77061551 |
| 16 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.77061551 |
| 17 | protein deneddylation (GO:0000338) | 3.76408292 |
| 18 | positive regulation of defense response to virus by host (GO:0002230) | 3.69024371 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.68681407 |
| 20 | positive regulation of prostaglandin secretion (GO:0032308) | 3.67623835 |
| 21 | maturation of SSU-rRNA (GO:0030490) | 3.52273460 |
| 22 | response to gravity (GO:0009629) | 3.48718345 |
| 23 | GTP biosynthetic process (GO:0006183) | 3.47927954 |
| 24 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.47710864 |
| 25 | termination of RNA polymerase III transcription (GO:0006386) | 3.47710864 |
| 26 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.46064337 |
| 27 | behavioral response to nicotine (GO:0035095) | 3.40053792 |
| 28 | pseudouridine synthesis (GO:0001522) | 3.39344658 |
| 29 | protein-cofactor linkage (GO:0018065) | 3.34752828 |
| 30 | regulation of immunoglobulin secretion (GO:0051023) | 3.34545998 |
| 31 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.33989215 |
| 32 | rRNA modification (GO:0000154) | 3.30656208 |
| 33 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.30001777 |
| 34 | protein neddylation (GO:0045116) | 3.28875088 |
| 35 | ribosomal large subunit biogenesis (GO:0042273) | 3.27041139 |
| 36 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.25104276 |
| 37 | cytidine metabolic process (GO:0046087) | 3.20779667 |
| 38 | cytidine catabolic process (GO:0006216) | 3.20779667 |
| 39 | cytidine deamination (GO:0009972) | 3.20779667 |
| 40 | maturation of 5.8S rRNA (GO:0000460) | 3.19803337 |
| 41 | fucose catabolic process (GO:0019317) | 3.13879568 |
| 42 | L-fucose metabolic process (GO:0042354) | 3.13879568 |
| 43 | L-fucose catabolic process (GO:0042355) | 3.13879568 |
| 44 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.13613027 |
| 45 | chaperone-mediated protein transport (GO:0072321) | 3.10186892 |
| 46 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.03153220 |
| 47 | ubiquinone biosynthetic process (GO:0006744) | 3.03100188 |
| 48 | viral transcription (GO:0019083) | 3.00899305 |
| 49 | tRNA processing (GO:0008033) | 2.99973170 |
| 50 | negative regulation of telomere maintenance (GO:0032205) | 2.98531213 |
| 51 | UTP biosynthetic process (GO:0006228) | 2.91994552 |
| 52 | cellular component biogenesis (GO:0044085) | 2.91503987 |
| 53 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.91199719 |
| 54 | mannosylation (GO:0097502) | 2.90800384 |
| 55 | translation (GO:0006412) | 2.90618528 |
| 56 | regulation of prostaglandin secretion (GO:0032306) | 2.90417752 |
| 57 | translational elongation (GO:0006414) | 2.89640158 |
| 58 | positive regulation of fatty acid transport (GO:2000193) | 2.88604301 |
| 59 | rRNA metabolic process (GO:0016072) | 2.87147892 |
| 60 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.86962814 |
| 61 | translational termination (GO:0006415) | 2.86660041 |
| 62 | rRNA processing (GO:0006364) | 2.86108788 |
| 63 | piRNA metabolic process (GO:0034587) | 2.85134655 |
| 64 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.85105584 |
| 65 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.84585847 |
| 66 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.84585847 |
| 67 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.83794655 |
| 68 | UTP metabolic process (GO:0046051) | 2.82644285 |
| 69 | respiratory chain complex IV assembly (GO:0008535) | 2.82148278 |
| 70 | regulation of chronic inflammatory response (GO:0002676) | 2.81798081 |
| 71 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.80724290 |
| 72 | cotranslational protein targeting to membrane (GO:0006613) | 2.79013432 |
| 73 | protein polyglutamylation (GO:0018095) | 2.78638015 |
| 74 | regulation of regulatory T cell differentiation (GO:0045589) | 2.78274855 |
| 75 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.77995985 |
| 76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.77498870 |
| 77 | protein targeting to ER (GO:0045047) | 2.77374733 |
| 78 | rRNA catabolic process (GO:0016075) | 2.75574835 |
| 79 | positive regulation of icosanoid secretion (GO:0032305) | 2.74282179 |
| 80 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.70762004 |
| 81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.69558838 |
| 82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.69558838 |
| 83 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.69558838 |
| 84 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.69369869 |
| 85 | isotype switching (GO:0045190) | 2.69369869 |
| 86 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.69369869 |
| 87 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.68851186 |
| 88 | protein localization to endoplasmic reticulum (GO:0070972) | 2.67548589 |
| 89 | ubiquinone metabolic process (GO:0006743) | 2.66974311 |
| 90 | ribosome biogenesis (GO:0042254) | 2.65985626 |
| 91 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.65059669 |
| 92 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.64884750 |
| 93 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.64884750 |
| 94 | electron transport chain (GO:0022900) | 2.64229802 |
| 95 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.63297242 |
| 96 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.62378617 |
| 97 | response to interferon-beta (GO:0035456) | 2.62309810 |
| 98 | respiratory electron transport chain (GO:0022904) | 2.59518667 |
| 99 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.59120753 |
| 100 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.58964883 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.53144065 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.36373365 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.07200531 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.74635758 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.38114637 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.29317954 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.25422714 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.18684983 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 3.07662782 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.93783965 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.85952484 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.76964554 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.55677598 |
| 14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.48653438 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.38967735 |
| 16 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.32113080 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.22191622 |
| 18 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.18020657 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12709312 |
| 20 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.01814232 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.95390691 |
| 22 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.88005251 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86198616 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.83021971 |
| 25 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.73348151 |
| 26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71643609 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.67619832 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.65984712 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.60760316 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.59232273 |
| 31 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.58808764 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.58267545 |
| 33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58066128 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.54591408 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51830936 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.42417692 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.40616560 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.39033844 |
| 39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.38231978 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.37711573 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.33400907 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.30640204 |
| 43 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.30577369 |
| 44 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29950039 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.29848807 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.29848807 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.28015456 |
| 48 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26233597 |
| 49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25858183 |
| 50 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.25028818 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.24539394 |
| 52 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.23512920 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.23423757 |
| 54 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.22374529 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.21516046 |
| 56 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19900697 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17315287 |
| 58 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15260853 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.14903145 |
| 60 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10258987 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.10256030 |
| 62 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.10114017 |
| 63 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09811171 |
| 64 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09811171 |
| 65 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.09640674 |
| 66 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.09599924 |
| 67 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08422665 |
| 68 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.07702074 |
| 69 | NCOR_22424771_ChIP-Seq_293T_Human | 1.07581181 |
| 70 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.07578657 |
| 71 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07570451 |
| 72 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.07131650 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05635784 |
| 74 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.04979304 |
| 75 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.04157813 |
| 76 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.04081037 |
| 77 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04034128 |
| 78 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03103344 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.01460167 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.01408986 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.00844595 |
| 82 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00594835 |
| 83 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00353136 |
| 84 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98824466 |
| 85 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98252647 |
| 86 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.97428855 |
| 87 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97041707 |
| 88 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.96777925 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.96646611 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95798856 |
| 91 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.95483794 |
| 92 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95401494 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.94759499 |
| 94 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.94521809 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.94521809 |
| 96 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.92736551 |
| 97 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.91995210 |
| 98 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91411184 |
| 99 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.88249087 |
| 100 | ERA_21632823_ChIP-Seq_H3396_Human | 0.86497795 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 3.08361905 |
| 2 | MP0002102_abnormal_ear_morphology | 2.93927268 |
| 3 | MP0005671_abnormal_response_to | 2.92014121 |
| 4 | MP0004147_increased_porphyrin_level | 2.66832399 |
| 5 | MP0004885_abnormal_endolymph | 2.65272186 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.64491248 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.45930543 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.40440070 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.36989531 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.32848155 |
| 11 | MP0002163_abnormal_gland_morphology | 2.21513366 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.10153630 |
| 13 | MP0008872_abnormal_physiological_respon | 2.06042963 |
| 14 | MP0006292_abnormal_olfactory_placode | 2.04192538 |
| 15 | MP0002876_abnormal_thyroid_physiology | 2.02145873 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 1.96483275 |
| 17 | MP0002736_abnormal_nociception_after | 1.95036237 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 1.93910075 |
| 19 | MP0000372_irregular_coat_pigmentation | 1.93002110 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.89805085 |
| 21 | MP0000685_abnormal_immune_system | 1.87264727 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.87140644 |
| 23 | MP0008058_abnormal_DNA_repair | 1.82138719 |
| 24 | MP0003786_premature_aging | 1.82072231 |
| 25 | MP0000569_abnormal_digit_pigmentation | 1.72830323 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.68669491 |
| 27 | MP0003718_maternal_effect | 1.63710033 |
| 28 | MP0004142_abnormal_muscle_tone | 1.59074768 |
| 29 | MP0003646_muscle_fatigue | 1.53495924 |
| 30 | MP0005360_urolithiasis | 1.45877708 |
| 31 | MP0003806_abnormal_nucleotide_metabolis | 1.43688771 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.42866864 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.40805228 |
| 34 | MP0002277_abnormal_respiratory_mucosa | 1.38053684 |
| 35 | MP0001905_abnormal_dopamine_level | 1.31397115 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.30637986 |
| 37 | MP0004742_abnormal_vestibular_system | 1.28349974 |
| 38 | MP0003195_calcinosis | 1.25975083 |
| 39 | MP0005253_abnormal_eye_physiology | 1.24167990 |
| 40 | MP0005387_immune_system_phenotype | 1.24056689 |
| 41 | MP0001790_abnormal_immune_system | 1.24056689 |
| 42 | MP0001800_abnormal_humoral_immune | 1.23850850 |
| 43 | MP0002938_white_spotting | 1.22531602 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.21420692 |
| 45 | MP0003866_abnormal_defecation | 1.18023930 |
| 46 | MP0001529_abnormal_vocalization | 1.18021953 |
| 47 | MP0001501_abnormal_sleep_pattern | 1.17029086 |
| 48 | MP0009764_decreased_sensitivity_to | 1.16523607 |
| 49 | MP0005000_abnormal_immune_tolerance | 1.16309451 |
| 50 | MP0005410_abnormal_fertilization | 1.16008009 |
| 51 | MP0009333_abnormal_splenocyte_physiolog | 1.14981557 |
| 52 | MP0002723_abnormal_immune_serum | 1.14627971 |
| 53 | MP0008775_abnormal_heart_ventricle | 1.13803622 |
| 54 | MP0003186_abnormal_redox_activity | 1.13188705 |
| 55 | MP0000427_abnormal_hair_cycle | 1.11845330 |
| 56 | MP0006035_abnormal_mitochondrial_morpho | 1.10012516 |
| 57 | MP0009785_altered_susceptibility_to | 1.09789131 |
| 58 | MP0005085_abnormal_gallbladder_physiolo | 1.09418565 |
| 59 | MP0003878_abnormal_ear_physiology | 1.06951954 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.06951954 |
| 61 | MP0002006_tumorigenesis | 1.06126666 |
| 62 | MP0002272_abnormal_nervous_system | 1.05012653 |
| 63 | MP0003436_decreased_susceptibility_to | 1.01309677 |
| 64 | MP0005636_abnormal_mineral_homeostasis | 0.99624568 |
| 65 | MP0002234_abnormal_pharynx_morphology | 0.98539289 |
| 66 | MP0002095_abnormal_skin_pigmentation | 0.97137959 |
| 67 | MP0005389_reproductive_system_phenotype | 0.96561633 |
| 68 | MP0008789_abnormal_olfactory_epithelium | 0.96092594 |
| 69 | MP0006276_abnormal_autonomic_nervous | 0.94569849 |
| 70 | MP0000647_abnormal_sebaceous_gland | 0.94016927 |
| 71 | MP0002452_abnormal_antigen_presenting | 0.93277326 |
| 72 | MP0006036_abnormal_mitochondrial_physio | 0.93201744 |
| 73 | MP0000613_abnormal_salivary_gland | 0.93175668 |
| 74 | MP0003880_abnormal_central_pattern | 0.92135916 |
| 75 | MP0003011_delayed_dark_adaptation | 0.91412895 |
| 76 | MP0003724_increased_susceptibility_to | 0.90493119 |
| 77 | MP0001542_abnormal_bone_strength | 0.89621657 |
| 78 | MP0001819_abnormal_immune_cell | 0.89103793 |
| 79 | MP0002420_abnormal_adaptive_immunity | 0.88647100 |
| 80 | MP0001440_abnormal_grooming_behavior | 0.87885624 |
| 81 | MP0001293_anophthalmia | 0.86953559 |
| 82 | MP0009745_abnormal_behavioral_response | 0.86473871 |
| 83 | MP0003763_abnormal_thymus_physiology | 0.86061995 |
| 84 | MP0001764_abnormal_homeostasis | 0.83872636 |
| 85 | MP0001873_stomach_inflammation | 0.82296301 |
| 86 | MP0002166_altered_tumor_susceptibility | 0.79905032 |
| 87 | MP0001485_abnormal_pinna_reflex | 0.79316737 |
| 88 | MP0001765_abnormal_ion_homeostasis | 0.79077238 |
| 89 | MP0005332_abnormal_amino_acid | 0.77014895 |
| 90 | MP0002160_abnormal_reproductive_system | 0.76981353 |
| 91 | MP0000049_abnormal_middle_ear | 0.74579552 |
| 92 | MP0002210_abnormal_sex_determination | 0.74504423 |
| 93 | MP0002693_abnormal_pancreas_physiology | 0.73136648 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.71794839 |
| 95 | MP0003638_abnormal_response/metabolism_ | 0.71449369 |
| 96 | MP0000689_abnormal_spleen_morphology | 0.70657322 |
| 97 | MP0002751_abnormal_autonomic_nervous | 0.70454854 |
| 98 | MP0001929_abnormal_gametogenesis | 0.67602753 |
| 99 | MP0010155_abnormal_intestine_physiology | 0.66818697 |
| 100 | MP0003693_abnormal_embryo_hatching | 0.65556911 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.92702607 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.65423990 |
| 3 | Pancreatic cysts (HP:0001737) | 3.57112423 |
| 4 | IgG deficiency (HP:0004315) | 3.55661572 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 3.51537563 |
| 6 | Increased CSF lactate (HP:0002490) | 3.49545834 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.42560348 |
| 8 | Acute encephalopathy (HP:0006846) | 3.41860839 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.27982197 |
| 10 | Hepatocellular necrosis (HP:0001404) | 3.24866354 |
| 11 | Abnormality of the renal cortex (HP:0011035) | 3.19424684 |
| 12 | Pancreatic fibrosis (HP:0100732) | 3.17082680 |
| 13 | Hepatic necrosis (HP:0002605) | 3.16841426 |
| 14 | Congenital stationary night blindness (HP:0007642) | 3.12410739 |
| 15 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.12249004 |
| 16 | Abnormality of alanine metabolism (HP:0010916) | 3.12249004 |
| 17 | Hyperalaninemia (HP:0003348) | 3.12249004 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.08350100 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 3.08350100 |
| 20 | Type II lissencephaly (HP:0007260) | 3.02217904 |
| 21 | Methylmalonic acidemia (HP:0002912) | 2.93882309 |
| 22 | Increased serum lactate (HP:0002151) | 2.93349030 |
| 23 | True hermaphroditism (HP:0010459) | 2.91760818 |
| 24 | Renal cortical cysts (HP:0000803) | 2.88553279 |
| 25 | Congenital, generalized hypertrichosis (HP:0004540) | 2.84739678 |
| 26 | Nephronophthisis (HP:0000090) | 2.79873818 |
| 27 | Abolished electroretinogram (ERG) (HP:0000550) | 2.79865755 |
| 28 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.77936305 |
| 29 | Increased hepatocellular lipid droplets (HP:0006565) | 2.76624900 |
| 30 | Hypoplasia of the uterus (HP:0000013) | 2.73473429 |
| 31 | Methylmalonic aciduria (HP:0012120) | 2.71242629 |
| 32 | Optic disc pallor (HP:0000543) | 2.57074987 |
| 33 | Lipid accumulation in hepatocytes (HP:0006561) | 2.56830301 |
| 34 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.56495833 |
| 35 | Cerebral edema (HP:0002181) | 2.56136674 |
| 36 | Type I transferrin isoform profile (HP:0003642) | 2.55170146 |
| 37 | Lactic acidosis (HP:0003128) | 2.53181848 |
| 38 | Prostate neoplasm (HP:0100787) | 2.52635999 |
| 39 | Abnormal number of erythroid precursors (HP:0012131) | 2.51971075 |
| 40 | Abnormality of the renal medulla (HP:0100957) | 2.51615459 |
| 41 | Stomatitis (HP:0010280) | 2.51245406 |
| 42 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.48605817 |
| 43 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.42878268 |
| 44 | Abnormality of the prostate (HP:0008775) | 2.40133336 |
| 45 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.36728537 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.30611980 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.30611980 |
| 48 | Abnormality of the pons (HP:0007361) | 2.24806816 |
| 49 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.22389410 |
| 50 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.15519949 |
| 51 | Renal Fanconi syndrome (HP:0001994) | 2.14232239 |
| 52 | Pancytopenia (HP:0001876) | 2.12620473 |
| 53 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.11012479 |
| 54 | Pendular nystagmus (HP:0012043) | 2.09934807 |
| 55 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.09922392 |
| 56 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.09922392 |
| 57 | Abnormal protein glycosylation (HP:0012346) | 2.09922392 |
| 58 | Abnormal glycosylation (HP:0012345) | 2.09922392 |
| 59 | Tongue fasciculations (HP:0001308) | 2.09269688 |
| 60 | Hypoplasia of the pons (HP:0012110) | 2.08791247 |
| 61 | Reduced antithrombin III activity (HP:0001976) | 2.07196515 |
| 62 | Lethargy (HP:0001254) | 2.05495082 |
| 63 | Respiratory failure (HP:0002878) | 2.04334982 |
| 64 | Sclerocornea (HP:0000647) | 2.01714318 |
| 65 | Asplenia (HP:0001746) | 2.01228102 |
| 66 | Adrenal hypoplasia (HP:0000835) | 2.01111783 |
| 67 | Delayed CNS myelination (HP:0002188) | 2.00268552 |
| 68 | Abnormality of T cell physiology (HP:0011840) | 1.99595846 |
| 69 | Reticulocytopenia (HP:0001896) | 1.98940937 |
| 70 | Hypoproteinemia (HP:0003075) | 1.98408370 |
| 71 | Short tibia (HP:0005736) | 1.98324146 |
| 72 | Increased intramyocellular lipid droplets (HP:0012240) | 1.96984211 |
| 73 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.96296779 |
| 74 | Exertional dyspnea (HP:0002875) | 1.91846290 |
| 75 | Constricted visual fields (HP:0001133) | 1.90815642 |
| 76 | Hypokalemic alkalosis (HP:0001949) | 1.90593624 |
| 77 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.88972092 |
| 78 | Attenuation of retinal blood vessels (HP:0007843) | 1.88639079 |
| 79 | Medial flaring of the eyebrow (HP:0010747) | 1.88069138 |
| 80 | Severe combined immunodeficiency (HP:0004430) | 1.87597060 |
| 81 | Polyuria (HP:0000103) | 1.85952078 |
| 82 | Testicular atrophy (HP:0000029) | 1.85164196 |
| 83 | Keratoconus (HP:0000563) | 1.84717102 |
| 84 | Increased corneal curvature (HP:0100692) | 1.84717102 |
| 85 | Large for gestational age (HP:0001520) | 1.83746744 |
| 86 | Abnormality of vitamin B metabolism (HP:0004340) | 1.82539938 |
| 87 | Abnormality of T cells (HP:0002843) | 1.82396953 |
| 88 | Exercise intolerance (HP:0003546) | 1.82016480 |
| 89 | Cystic liver disease (HP:0006706) | 1.80227846 |
| 90 | Glycosuria (HP:0003076) | 1.79912584 |
| 91 | Abnormality of urine glucose concentration (HP:0011016) | 1.79912584 |
| 92 | Hypothermia (HP:0002045) | 1.78355388 |
| 93 | Type 2 muscle fiber atrophy (HP:0003554) | 1.78133334 |
| 94 | Colon cancer (HP:0003003) | 1.76394607 |
| 95 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.75763163 |
| 96 | Polydipsia (HP:0001959) | 1.75609555 |
| 97 | Abnormal drinking behavior (HP:0030082) | 1.75609555 |
| 98 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.75576027 |
| 99 | Conical tooth (HP:0000698) | 1.75550795 |
| 100 | Severe muscular hypotonia (HP:0006829) | 1.75524895 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.89204240 |
| 2 | TLK1 | 3.64317077 |
| 3 | TXK | 3.61297635 |
| 4 | MAP4K2 | 3.50870171 |
| 5 | TAOK3 | 2.85090256 |
| 6 | ADRBK2 | 2.82376941 |
| 7 | NUAK1 | 2.80328760 |
| 8 | NME2 | 2.77658637 |
| 9 | ZAK | 2.51855199 |
| 10 | BCKDK | 2.23376115 |
| 11 | VRK1 | 2.01243473 |
| 12 | STK16 | 2.00494711 |
| 13 | TSSK6 | 1.97127716 |
| 14 | FRK | 1.86417789 |
| 15 | BUB1 | 1.75616481 |
| 16 | MST4 | 1.75540492 |
| 17 | GRK1 | 1.73149913 |
| 18 | BMPR1B | 1.66488893 |
| 19 | TIE1 | 1.60938855 |
| 20 | TAF1 | 1.59553888 |
| 21 | PHKG2 | 1.54978311 |
| 22 | PHKG1 | 1.54978311 |
| 23 | WNK4 | 1.45775378 |
| 24 | EIF2AK3 | 1.44826202 |
| 25 | MAPKAPK3 | 1.31458865 |
| 26 | SRPK1 | 1.31176032 |
| 27 | PLK4 | 1.25971913 |
| 28 | DAPK1 | 1.24657876 |
| 29 | NEK1 | 1.23412818 |
| 30 | IKBKB | 1.19785111 |
| 31 | GRK5 | 1.15538600 |
| 32 | TESK2 | 1.11371571 |
| 33 | TRIM28 | 1.11371029 |
| 34 | OXSR1 | 1.11055857 |
| 35 | LIMK1 | 1.04925113 |
| 36 | TGFBR1 | 1.00109431 |
| 37 | KIT | 0.98353433 |
| 38 | GRK7 | 0.97936253 |
| 39 | STK39 | 0.95999976 |
| 40 | CSNK1G3 | 0.95486525 |
| 41 | MAP2K2 | 0.93513655 |
| 42 | PASK | 0.93490669 |
| 43 | EIF2AK2 | 0.93451317 |
| 44 | INSRR | 0.92060300 |
| 45 | PLK3 | 0.91500493 |
| 46 | TEC | 0.91229956 |
| 47 | MAPKAPK5 | 0.91027975 |
| 48 | PDK2 | 0.89787934 |
| 49 | ITK | 0.87064737 |
| 50 | EIF2AK1 | 0.85932723 |
| 51 | PINK1 | 0.84894866 |
| 52 | GRK6 | 0.84673761 |
| 53 | WNK3 | 0.80928863 |
| 54 | CDK19 | 0.80468036 |
| 55 | CSNK1G1 | 0.79550056 |
| 56 | DYRK2 | 0.79178310 |
| 57 | CSNK1G2 | 0.78574743 |
| 58 | MKNK1 | 0.76675588 |
| 59 | ADRBK1 | 0.73808197 |
| 60 | CSNK1A1L | 0.72733394 |
| 61 | KDR | 0.68584311 |
| 62 | MAP4K1 | 0.68297276 |
| 63 | CAMKK2 | 0.67352027 |
| 64 | CDK8 | 0.67038062 |
| 65 | RPS6KA5 | 0.65913058 |
| 66 | PLK2 | 0.63922333 |
| 67 | MAP3K12 | 0.61151642 |
| 68 | MKNK2 | 0.60864748 |
| 69 | DAPK2 | 0.59624670 |
| 70 | IKBKE | 0.56702159 |
| 71 | LMTK2 | 0.55876436 |
| 72 | TESK1 | 0.55585077 |
| 73 | FES | 0.51505046 |
| 74 | MAP3K14 | 0.50879360 |
| 75 | TNIK | 0.44536763 |
| 76 | SYK | 0.44476413 |
| 77 | ATR | 0.43955262 |
| 78 | MAPK13 | 0.42910584 |
| 79 | PRKCQ | 0.42758581 |
| 80 | PRKCG | 0.42155388 |
| 81 | PRKCE | 0.42036874 |
| 82 | ERBB3 | 0.40512967 |
| 83 | BCR | 0.39931088 |
| 84 | ABL2 | 0.39152360 |
| 85 | IGF1R | 0.39093949 |
| 86 | AURKA | 0.38728322 |
| 87 | PIM2 | 0.36520799 |
| 88 | PRKCI | 0.36312188 |
| 89 | CSNK1A1 | 0.35241618 |
| 90 | CSNK2A2 | 0.34630506 |
| 91 | ACVR1B | 0.33619085 |
| 92 | CHEK2 | 0.33273579 |
| 93 | MAP2K6 | 0.32541238 |
| 94 | CSNK2A1 | 0.32219628 |
| 95 | CHUK | 0.32028555 |
| 96 | LCK | 0.29468135 |
| 97 | PRKACA | 0.27908392 |
| 98 | TBK1 | 0.27331245 |
| 99 | MAPK15 | 0.27061719 |
| 100 | DAPK3 | 0.26070407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.67271229 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.49861952 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.99228297 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.72530301 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.67855924 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.55270066 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.36226480 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.34765157 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.25432005 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.17932666 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.16693551 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.02545399 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.92682776 |
| 14 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.90769844 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.88175951 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.81602652 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.63601956 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61025392 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.58385441 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.58050711 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.57425546 |
| 22 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.54989919 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.53284872 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.52724621 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.51502769 |
| 26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.51373220 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.46810060 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.46201797 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.36790072 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.36369543 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.32435553 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.26359767 |
| 33 | RNA transport_Homo sapiens_hsa03013 | 1.25357635 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.24366305 |
| 35 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.23987227 |
| 36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22940160 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.21677307 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.21151908 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.20887570 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19278028 |
| 41 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.15655333 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12088961 |
| 43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.07209146 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 1.04595162 |
| 45 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.03752510 |
| 46 | DNA replication_Homo sapiens_hsa03030 | 1.01879133 |
| 47 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.01162725 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99516920 |
| 49 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.98796307 |
| 50 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.98649370 |
| 51 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.97432583 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97169186 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.95525044 |
| 54 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92792811 |
| 55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.92338394 |
| 56 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91645822 |
| 57 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.90459720 |
| 58 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.87442890 |
| 59 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.86639295 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.85949928 |
| 61 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.81906382 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78415293 |
| 63 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.77939852 |
| 64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77157458 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.76253992 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.70817696 |
| 67 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.68180716 |
| 68 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.68161023 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66068722 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64898420 |
| 71 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64772757 |
| 72 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60359553 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.55444995 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.55400046 |
| 75 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.55337097 |
| 76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.53736219 |
| 77 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.53194310 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52731039 |
| 79 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52239397 |
| 80 | Salivary secretion_Homo sapiens_hsa04970 | 0.52237835 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52053376 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51571145 |
| 83 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.46768525 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45862750 |
| 85 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45426985 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.44978408 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.43712133 |
| 88 | Taste transduction_Homo sapiens_hsa04742 | 0.41255762 |
| 89 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40368871 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40287985 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38560274 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36161123 |
| 93 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.36080573 |
| 94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.35309613 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.35239514 |
| 96 | Viral myocarditis_Homo sapiens_hsa05416 | 0.35101039 |
| 97 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.33288932 |
| 98 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.32674262 |
| 99 | Mineral absorption_Homo sapiens_hsa04978 | 0.30598743 |
| 100 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.30352848 |

