

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.33358551 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.29806241 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.07707512 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.07707512 |
| 5 | rRNA modification (GO:0000154) | 5.03957503 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.00925204 |
| 7 | proteasome assembly (GO:0043248) | 4.21137802 |
| 8 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.20083072 |
| 9 | rRNA methylation (GO:0031167) | 4.19100121 |
| 10 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.18934145 |
| 11 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.18018958 |
| 12 | maturation of 5.8S rRNA (GO:0000460) | 4.07101122 |
| 13 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.94100125 |
| 14 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.94100125 |
| 15 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.90108805 |
| 16 | protein neddylation (GO:0045116) | 3.87745400 |
| 17 | cullin deneddylation (GO:0010388) | 3.73492251 |
| 18 | termination of RNA polymerase III transcription (GO:0006386) | 3.69503589 |
| 19 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.69503589 |
| 20 | protein deneddylation (GO:0000338) | 3.59327622 |
| 21 | ribosomal large subunit biogenesis (GO:0042273) | 3.58375799 |
| 22 | chaperone-mediated protein transport (GO:0072321) | 3.53755615 |
| 23 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.46973047 |
| 24 | inner mitochondrial membrane organization (GO:0007007) | 3.46408971 |
| 25 | protein complex biogenesis (GO:0070271) | 3.43780564 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.43727625 |
| 27 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.38811144 |
| 28 | electron transport chain (GO:0022900) | 3.38441588 |
| 29 | ribosomal small subunit assembly (GO:0000028) | 3.38179015 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.37651792 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 3.37651792 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.37651792 |
| 33 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.36893380 |
| 34 | respiratory electron transport chain (GO:0022904) | 3.35267037 |
| 35 | behavioral response to nicotine (GO:0035095) | 3.33903393 |
| 36 | respiratory chain complex IV assembly (GO:0008535) | 3.31288765 |
| 37 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.30033407 |
| 38 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.30033407 |
| 39 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.30033407 |
| 40 | protein-cofactor linkage (GO:0018065) | 3.29670256 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.28499291 |
| 42 | viral transcription (GO:0019083) | 3.25853756 |
| 43 | GTP biosynthetic process (GO:0006183) | 3.25627540 |
| 44 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.25312990 |
| 45 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.25312990 |
| 46 | translational termination (GO:0006415) | 3.22094295 |
| 47 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.20975200 |
| 48 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.15976171 |
| 49 | cotranslational protein targeting to membrane (GO:0006613) | 3.12408696 |
| 50 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.10097943 |
| 51 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.10097943 |
| 52 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.08783171 |
| 53 | protein targeting to ER (GO:0045047) | 3.07796591 |
| 54 | negative regulation of ligase activity (GO:0051352) | 3.05269574 |
| 55 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.05269574 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.05180039 |
| 57 | translational elongation (GO:0006414) | 3.04517204 |
| 58 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.01506822 |
| 59 | maturation of SSU-rRNA (GO:0030490) | 2.97148929 |
| 60 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.96634131 |
| 61 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.95445812 |
| 62 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.94455640 |
| 63 | piRNA metabolic process (GO:0034587) | 2.92140582 |
| 64 | protein localization to endoplasmic reticulum (GO:0070972) | 2.90488940 |
| 65 | intracellular protein transmembrane import (GO:0044743) | 2.89792635 |
| 66 | ATP biosynthetic process (GO:0006754) | 2.85914740 |
| 67 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.83784982 |
| 68 | translation (GO:0006412) | 2.83677631 |
| 69 | fucose catabolic process (GO:0019317) | 2.83542489 |
| 70 | L-fucose metabolic process (GO:0042354) | 2.83542489 |
| 71 | L-fucose catabolic process (GO:0042355) | 2.83542489 |
| 72 | platelet dense granule organization (GO:0060155) | 2.83008911 |
| 73 | pseudouridine synthesis (GO:0001522) | 2.82922230 |
| 74 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.82849598 |
| 75 | mannosylation (GO:0097502) | 2.81988595 |
| 76 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.78366203 |
| 77 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.78366203 |
| 78 | cytochrome complex assembly (GO:0017004) | 2.76942433 |
| 79 | tRNA processing (GO:0008033) | 2.76916151 |
| 80 | GMP metabolic process (GO:0046037) | 2.76627686 |
| 81 | ubiquinone metabolic process (GO:0006743) | 2.75847895 |
| 82 | rRNA metabolic process (GO:0016072) | 2.70350756 |
| 83 | rRNA processing (GO:0006364) | 2.70174651 |
| 84 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.70024090 |
| 85 | positive regulation of ligase activity (GO:0051351) | 2.69970634 |
| 86 | regulation of chronic inflammatory response (GO:0002676) | 2.68816028 |
| 87 | hydrogen ion transmembrane transport (GO:1902600) | 2.68605087 |
| 88 | translational initiation (GO:0006413) | 2.68512719 |
| 89 | UTP biosynthetic process (GO:0006228) | 2.68376103 |
| 90 | S-adenosylmethionine metabolic process (GO:0046500) | 2.67861670 |
| 91 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.66876455 |
| 92 | proton transport (GO:0015992) | 2.66407318 |
| 93 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.66236253 |
| 94 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.66236253 |
| 95 | isotype switching (GO:0045190) | 2.66236253 |
| 96 | response to pheromone (GO:0019236) | 2.63557732 |
| 97 | termination of RNA polymerase I transcription (GO:0006363) | 2.62655395 |
| 98 | rRNA catabolic process (GO:0016075) | 2.62482480 |
| 99 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.60910739 |
| 100 | hydrogen transport (GO:0006818) | 2.59569865 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.55167597 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35261607 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.99343216 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.44440688 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.35965979 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.25405380 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.06362755 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.03374595 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.76057385 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.67104386 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.66040646 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.50237593 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.45538881 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.44847695 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.32497849 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.17064513 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10120026 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.08852279 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 2.06960150 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.04893502 |
| 21 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.99724510 |
| 22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.97745415 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.95021126 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.93082024 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.86514603 |
| 26 | FUS_26573619_Chip-Seq_HEK293_Human | 1.83574428 |
| 27 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.83276029 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.80724001 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.73284989 |
| 30 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.64269012 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.62736519 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62622111 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.61250926 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.59954372 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.55212696 |
| 36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46081471 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.45524554 |
| 38 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.45050691 |
| 39 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.43788800 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.43291489 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.40803873 |
| 42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.39084192 |
| 43 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38018938 |
| 44 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.35604186 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.34368159 |
| 46 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32862034 |
| 47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.32584139 |
| 48 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.32584139 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32191031 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.31932413 |
| 51 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.31496310 |
| 52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.31303027 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.29467996 |
| 54 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.28869706 |
| 55 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.28797713 |
| 56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27898919 |
| 57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26444245 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26444245 |
| 59 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.25373713 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.25097872 |
| 61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.24488551 |
| 62 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.23625376 |
| 63 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21752644 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.21404512 |
| 65 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.19568309 |
| 66 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.18733167 |
| 67 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15296541 |
| 68 | AR_20517297_ChIP-Seq_VCAP_Human | 1.13331734 |
| 69 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.12784182 |
| 70 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10681931 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10266582 |
| 72 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.09459562 |
| 73 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07350617 |
| 74 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.07304796 |
| 75 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.04666745 |
| 76 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03911684 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.00658518 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.00658518 |
| 79 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.00616335 |
| 80 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.98928862 |
| 81 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.97904779 |
| 82 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.97817549 |
| 83 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96361604 |
| 84 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95619791 |
| 85 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93080443 |
| 86 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92949650 |
| 87 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.92037126 |
| 88 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90272831 |
| 89 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.89593437 |
| 90 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.89552066 |
| 91 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.89453538 |
| 92 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88804143 |
| 93 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.88593685 |
| 94 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.87130959 |
| 95 | NCOR_22424771_ChIP-Seq_293T_Human | 0.87005167 |
| 96 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.86464842 |
| 97 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.85674939 |
| 98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.85282312 |
| 99 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.84183945 |
| 100 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.82188700 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 3.46973315 |
| 2 | MP0002102_abnormal_ear_morphology | 3.37112105 |
| 3 | MP0009379_abnormal_foot_pigmentation | 3.16219170 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.84703581 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.81455040 |
| 6 | MP0002138_abnormal_hepatobiliary_system | 2.63476719 |
| 7 | MP0003283_abnormal_digestive_organ | 2.58803400 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 2.52574293 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.34894282 |
| 10 | MP0008058_abnormal_DNA_repair | 2.30186526 |
| 11 | MP0005671_abnormal_response_to | 2.22514492 |
| 12 | MP0004147_increased_porphyrin_level | 2.17643135 |
| 13 | MP0002938_white_spotting | 2.06671904 |
| 14 | MP0001835_abnormal_antigen_presentation | 2.03306751 |
| 15 | MP0002736_abnormal_nociception_after | 1.98945097 |
| 16 | MP0003136_yellow_coat_color | 1.97040226 |
| 17 | MP0000685_abnormal_immune_system | 1.83651990 |
| 18 | MP0006292_abnormal_olfactory_placode | 1.81988787 |
| 19 | MP0003011_delayed_dark_adaptation | 1.81601364 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.81314026 |
| 21 | MP0000383_abnormal_hair_follicle | 1.73670003 |
| 22 | MP0004885_abnormal_endolymph | 1.68649955 |
| 23 | MP0003195_calcinosis | 1.66870701 |
| 24 | MP0005253_abnormal_eye_physiology | 1.59787992 |
| 25 | MP0003718_maternal_effect | 1.57023414 |
| 26 | MP0002006_tumorigenesis | 1.54032804 |
| 27 | MP0005645_abnormal_hypothalamus_physiol | 1.53415221 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.53367657 |
| 29 | MP0008872_abnormal_physiological_respon | 1.52050985 |
| 30 | MP0002638_abnormal_pupillary_reflex | 1.50625826 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.50077252 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.47274966 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.47141178 |
| 34 | MP0002751_abnormal_autonomic_nervous | 1.46766837 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.44577433 |
| 36 | MP0002234_abnormal_pharynx_morphology | 1.44061233 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.43728361 |
| 38 | MP0005646_abnormal_pituitary_gland | 1.43705480 |
| 39 | MP0002277_abnormal_respiratory_mucosa | 1.43353361 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.39130398 |
| 41 | MP0009785_altered_susceptibility_to | 1.36471669 |
| 42 | MP0001529_abnormal_vocalization | 1.32096650 |
| 43 | MP0001293_anophthalmia | 1.31662385 |
| 44 | MP0006035_abnormal_mitochondrial_morpho | 1.27264355 |
| 45 | MP0003786_premature_aging | 1.26548649 |
| 46 | MP0001501_abnormal_sleep_pattern | 1.24101051 |
| 47 | MP0002876_abnormal_thyroid_physiology | 1.20495951 |
| 48 | MP0003878_abnormal_ear_physiology | 1.18809660 |
| 49 | MP0005377_hearing/vestibular/ear_phenot | 1.18809660 |
| 50 | MP0004142_abnormal_muscle_tone | 1.17129432 |
| 51 | MP0002282_abnormal_trachea_morphology | 1.16767896 |
| 52 | MP0010094_abnormal_chromosome_stability | 1.15614349 |
| 53 | MP0003787_abnormal_imprinting | 1.14698277 |
| 54 | MP0005174_abnormal_tail_pigmentation | 1.14033912 |
| 55 | MP0006276_abnormal_autonomic_nervous | 1.09817606 |
| 56 | MP0009764_decreased_sensitivity_to | 1.08246918 |
| 57 | MP0003646_muscle_fatigue | 1.07846323 |
| 58 | MP0006036_abnormal_mitochondrial_physio | 1.07414522 |
| 59 | MP0003880_abnormal_central_pattern | 1.06873342 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 1.05464902 |
| 61 | MP0000566_synostosis | 1.04387802 |
| 62 | MP0004957_abnormal_blastocyst_morpholog | 1.01952625 |
| 63 | MP0003186_abnormal_redox_activity | 0.99720678 |
| 64 | MP0002095_abnormal_skin_pigmentation | 0.97272989 |
| 65 | MP0002272_abnormal_nervous_system | 0.96941762 |
| 66 | MP0001790_abnormal_immune_system | 0.96829195 |
| 67 | MP0005387_immune_system_phenotype | 0.96829195 |
| 68 | MP0001485_abnormal_pinna_reflex | 0.94060763 |
| 69 | MP0001984_abnormal_olfaction | 0.92763271 |
| 70 | MP0004145_abnormal_muscle_electrophysio | 0.92328905 |
| 71 | MP0003693_abnormal_embryo_hatching | 0.91055170 |
| 72 | MP0008995_early_reproductive_senescence | 0.90551313 |
| 73 | MP0001919_abnormal_reproductive_system | 0.88405381 |
| 74 | MP0001800_abnormal_humoral_immune | 0.87584474 |
| 75 | MP0000427_abnormal_hair_cycle | 0.87434253 |
| 76 | MP0005389_reproductive_system_phenotype | 0.84722306 |
| 77 | MP0008007_abnormal_cellular_replicative | 0.82037290 |
| 78 | MP0010678_abnormal_skin_adnexa | 0.81389702 |
| 79 | MP0008057_abnormal_DNA_replication | 0.79243271 |
| 80 | MP0005000_abnormal_immune_tolerance | 0.78689603 |
| 81 | MP0010386_abnormal_urinary_bladder | 0.76933633 |
| 82 | MP0000647_abnormal_sebaceous_gland | 0.76435564 |
| 83 | MP0003724_increased_susceptibility_to | 0.71951647 |
| 84 | MP0001929_abnormal_gametogenesis | 0.71932169 |
| 85 | MP0005636_abnormal_mineral_homeostasis | 0.71114116 |
| 86 | MP0000569_abnormal_digit_pigmentation | 0.70058101 |
| 87 | MP0005410_abnormal_fertilization | 0.69837431 |
| 88 | MP0001873_stomach_inflammation | 0.69548639 |
| 89 | MP0003866_abnormal_defecation | 0.69078224 |
| 90 | MP0002723_abnormal_immune_serum | 0.68817171 |
| 91 | MP0001905_abnormal_dopamine_level | 0.65743445 |
| 92 | MP0002210_abnormal_sex_determination | 0.65532540 |
| 93 | MP0009697_abnormal_copulation | 0.65057023 |
| 94 | MP0005167_abnormal_blood-brain_barrier | 0.63863165 |
| 95 | MP0004742_abnormal_vestibular_system | 0.62944726 |
| 96 | MP0000613_abnormal_salivary_gland | 0.62332235 |
| 97 | MP0005195_abnormal_posterior_eye | 0.62097671 |
| 98 | MP0000653_abnormal_sex_gland | 0.61696520 |
| 99 | MP0002452_abnormal_antigen_presenting | 0.61456188 |
| 100 | MP0001819_abnormal_immune_cell | 0.60535100 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.55008741 |
| 2 | Congenital, generalized hypertrichosis (HP:0004540) | 4.12269758 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.06130030 |
| 4 | Acute encephalopathy (HP:0006846) | 3.98959549 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.93988526 |
| 6 | Increased CSF lactate (HP:0002490) | 3.89866321 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.83780321 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.69815292 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.50819473 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.47995467 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.47825966 |
| 12 | Pancreatic cysts (HP:0001737) | 3.14912241 |
| 13 | Hepatic necrosis (HP:0002605) | 3.05157291 |
| 14 | 3-Methylglutaconic aciduria (HP:0003535) | 3.03503314 |
| 15 | Type II lissencephaly (HP:0007260) | 2.93366036 |
| 16 | True hermaphroditism (HP:0010459) | 2.91023519 |
| 17 | IgG deficiency (HP:0004315) | 2.90367429 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 2.84892966 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 2.84892966 |
| 20 | Abnormality of the pons (HP:0007361) | 2.82573108 |
| 21 | Hypoplasia of the pons (HP:0012110) | 2.81288563 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.79116693 |
| 23 | Cerebral edema (HP:0002181) | 2.74343561 |
| 24 | Nephronophthisis (HP:0000090) | 2.73404746 |
| 25 | Stomatitis (HP:0010280) | 2.70068405 |
| 26 | Optic disc pallor (HP:0000543) | 2.69791601 |
| 27 | Pancreatic fibrosis (HP:0100732) | 2.67031130 |
| 28 | Increased serum lactate (HP:0002151) | 2.66134730 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.64580294 |
| 30 | Exertional dyspnea (HP:0002875) | 2.62705903 |
| 31 | Abolished electroretinogram (ERG) (HP:0000550) | 2.60458586 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.57721884 |
| 33 | Methylmalonic acidemia (HP:0002912) | 2.50681226 |
| 34 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.47935105 |
| 35 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.43789930 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.42405963 |
| 37 | Prostate neoplasm (HP:0100787) | 2.37788450 |
| 38 | Type I transferrin isoform profile (HP:0003642) | 2.34030442 |
| 39 | Reticulocytopenia (HP:0001896) | 2.33147485 |
| 40 | Abnormality of the prostate (HP:0008775) | 2.31583638 |
| 41 | Abnormality of the renal medulla (HP:0100957) | 2.29799753 |
| 42 | Lactic acidosis (HP:0003128) | 2.28575024 |
| 43 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.25459696 |
| 44 | Hypoproteinemia (HP:0003075) | 2.24106346 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.23927380 |
| 46 | Type 2 muscle fiber atrophy (HP:0003554) | 2.21748899 |
| 47 | Leukodystrophy (HP:0002415) | 2.21409131 |
| 48 | Bilateral microphthalmos (HP:0007633) | 2.18707436 |
| 49 | Respiratory failure (HP:0002878) | 2.18359833 |
| 50 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.12739192 |
| 51 | Absent/shortened dynein arms (HP:0200106) | 2.12739192 |
| 52 | Glycosuria (HP:0003076) | 2.11851885 |
| 53 | Abnormality of urine glucose concentration (HP:0011016) | 2.11851885 |
| 54 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.08791130 |
| 55 | Macrocytic anemia (HP:0001972) | 2.08319148 |
| 56 | Septo-optic dysplasia (HP:0100842) | 2.08048475 |
| 57 | Keratoconus (HP:0000563) | 2.05656450 |
| 58 | Increased corneal curvature (HP:0100692) | 2.05656450 |
| 59 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.98558782 |
| 60 | Methylmalonic aciduria (HP:0012120) | 1.98339028 |
| 61 | Cerebellar dysplasia (HP:0007033) | 1.95554861 |
| 62 | Polydipsia (HP:0001959) | 1.94305501 |
| 63 | Abnormal drinking behavior (HP:0030082) | 1.94305501 |
| 64 | Testicular atrophy (HP:0000029) | 1.94274907 |
| 65 | Pancytopenia (HP:0001876) | 1.93429528 |
| 66 | Stomach cancer (HP:0012126) | 1.93296204 |
| 67 | Sclerocornea (HP:0000647) | 1.92822091 |
| 68 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92210052 |
| 69 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.90775643 |
| 70 | Renal cortical cysts (HP:0000803) | 1.90080467 |
| 71 | Lethargy (HP:0001254) | 1.89587658 |
| 72 | Hypomagnesemia (HP:0002917) | 1.86599229 |
| 73 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.86494036 |
| 74 | Respiratory difficulties (HP:0002880) | 1.86136226 |
| 75 | Dyschromatopsia (HP:0007641) | 1.85878109 |
| 76 | Abnormality of T cell physiology (HP:0011840) | 1.85128848 |
| 77 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.85117499 |
| 78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.84765589 |
| 79 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.84512710 |
| 80 | Abnormal biliary tract physiology (HP:0012439) | 1.82876165 |
| 81 | Bile duct proliferation (HP:0001408) | 1.82876165 |
| 82 | Increased intramyocellular lipid droplets (HP:0012240) | 1.81990264 |
| 83 | Polyuria (HP:0000103) | 1.81888941 |
| 84 | Abnormal protein glycosylation (HP:0012346) | 1.79267762 |
| 85 | Abnormal glycosylation (HP:0012345) | 1.79267762 |
| 86 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.79267762 |
| 87 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.79267762 |
| 88 | Pendular nystagmus (HP:0012043) | 1.78315752 |
| 89 | Medial flaring of the eyebrow (HP:0010747) | 1.78115263 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.77826351 |
| 91 | Hyperalaninemia (HP:0003348) | 1.77826351 |
| 92 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.77826351 |
| 93 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.77148349 |
| 94 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.77148349 |
| 95 | IgM deficiency (HP:0002850) | 1.76103244 |
| 96 | Hypothermia (HP:0002045) | 1.75413570 |
| 97 | Optic nerve hypoplasia (HP:0000609) | 1.73688520 |
| 98 | Absent thumb (HP:0009777) | 1.73036558 |
| 99 | Meckel diverticulum (HP:0002245) | 1.71814059 |
| 100 | Exercise intolerance (HP:0003546) | 1.71809345 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 4.43534736 |
| 2 | VRK2 | 3.84428518 |
| 3 | NUAK1 | 3.45044726 |
| 4 | TLK1 | 3.40205886 |
| 5 | TSSK6 | 2.88926473 |
| 6 | MST4 | 2.68698703 |
| 7 | ZAK | 2.67933002 |
| 8 | MAP4K2 | 2.57478929 |
| 9 | BMPR1B | 2.32601270 |
| 10 | BUB1 | 2.27787612 |
| 11 | VRK1 | 2.09541854 |
| 12 | TXK | 2.03702069 |
| 13 | PINK1 | 2.02345000 |
| 14 | EIF2AK3 | 1.98408178 |
| 15 | PASK | 1.91406549 |
| 16 | STK16 | 1.89145784 |
| 17 | GRK1 | 1.87209677 |
| 18 | WNK3 | 1.81430240 |
| 19 | ADRBK2 | 1.77921452 |
| 20 | NEK1 | 1.65974681 |
| 21 | OXSR1 | 1.65586051 |
| 22 | FRK | 1.64259264 |
| 23 | PLK3 | 1.54335067 |
| 24 | ACVR1B | 1.46752987 |
| 25 | WNK4 | 1.46546005 |
| 26 | KIT | 1.45053633 |
| 27 | NME1 | 1.44312876 |
| 28 | MKNK1 | 1.37464157 |
| 29 | MKNK2 | 1.32573225 |
| 30 | SRPK1 | 1.30515735 |
| 31 | EIF2AK1 | 1.29002924 |
| 32 | STK39 | 1.19281088 |
| 33 | TAF1 | 1.16066041 |
| 34 | FGFR2 | 1.12298679 |
| 35 | TNIK | 1.11401006 |
| 36 | PNCK | 1.07820232 |
| 37 | TGFBR1 | 1.07716803 |
| 38 | EIF2AK2 | 1.02017053 |
| 39 | PLK4 | 0.99362396 |
| 40 | IKBKB | 0.99222605 |
| 41 | PLK2 | 0.96660068 |
| 42 | TRIM28 | 0.95545069 |
| 43 | CDK8 | 0.91872925 |
| 44 | BMPR2 | 0.91542025 |
| 45 | WEE1 | 0.91117104 |
| 46 | PHKG1 | 0.89725278 |
| 47 | PHKG2 | 0.89725278 |
| 48 | CDC7 | 0.87756148 |
| 49 | INSRR | 0.87636689 |
| 50 | CDK19 | 0.87478569 |
| 51 | MAP3K12 | 0.83334731 |
| 52 | TEC | 0.79470856 |
| 53 | BRSK2 | 0.73902628 |
| 54 | DYRK2 | 0.73415726 |
| 55 | STK38L | 0.68204161 |
| 56 | TIE1 | 0.64278658 |
| 57 | CSNK1G2 | 0.63659996 |
| 58 | MAPKAPK5 | 0.61900193 |
| 59 | CSNK1G3 | 0.61597741 |
| 60 | RPS6KA5 | 0.59987497 |
| 61 | ITK | 0.59693894 |
| 62 | MAP4K1 | 0.59365664 |
| 63 | ERBB3 | 0.58312535 |
| 64 | MAP2K6 | 0.57218101 |
| 65 | MAP2K2 | 0.56831192 |
| 66 | CSNK1G1 | 0.55956037 |
| 67 | PDK2 | 0.53605660 |
| 68 | BCKDK | 0.52676734 |
| 69 | ALK | 0.49443655 |
| 70 | MAPKAPK3 | 0.47927680 |
| 71 | MYLK | 0.46937766 |
| 72 | PLK1 | 0.45988397 |
| 73 | DAPK2 | 0.44646627 |
| 74 | IKBKE | 0.44310054 |
| 75 | CSNK1A1L | 0.44289179 |
| 76 | IRAK1 | 0.43343272 |
| 77 | PBK | 0.43070680 |
| 78 | AURKB | 0.42089245 |
| 79 | SIK3 | 0.41246007 |
| 80 | CAMKK2 | 0.39677138 |
| 81 | ADRBK1 | 0.39270711 |
| 82 | GRK6 | 0.39030066 |
| 83 | PRKCE | 0.38744974 |
| 84 | DAPK1 | 0.38734813 |
| 85 | MAP3K14 | 0.37734558 |
| 86 | ATR | 0.37524921 |
| 87 | FLT3 | 0.36541119 |
| 88 | NLK | 0.36267164 |
| 89 | CSNK2A1 | 0.35912524 |
| 90 | PRKCG | 0.35735243 |
| 91 | JAK3 | 0.35110052 |
| 92 | SYK | 0.34378239 |
| 93 | MAPK13 | 0.34333437 |
| 94 | FES | 0.34176505 |
| 95 | CSNK2A2 | 0.32861201 |
| 96 | PRKCQ | 0.31692427 |
| 97 | IGF1R | 0.30588730 |
| 98 | LYN | 0.29101754 |
| 99 | FGFR1 | 0.28813991 |
| 100 | MUSK | 0.27731786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.30168442 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.25080399 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.23978322 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.00834240 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.84269614 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.69109397 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.63878430 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.42096629 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.32718882 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.25071958 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.12057727 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11444792 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.10646216 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.93780365 |
| 15 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.92708364 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.82665905 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.72255595 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.70752162 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.70256647 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.67542265 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.66275940 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.60630630 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.58939274 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.54539097 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.53151909 |
| 26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.46642221 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.45505513 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45010433 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.42512671 |
| 30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.41270082 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.39500862 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.30645138 |
| 33 | RNA transport_Homo sapiens_hsa03013 | 1.27638451 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.18717170 |
| 35 | DNA replication_Homo sapiens_hsa03030 | 1.17394884 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.16392439 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.14687007 |
| 38 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.12081313 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.11551524 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.11120893 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.10742006 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.10501735 |
| 43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.08835773 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05791591 |
| 45 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.04114583 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.03607564 |
| 47 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.01263013 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.99595703 |
| 49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.91705386 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.84985067 |
| 51 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.83134044 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 0.81589409 |
| 53 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79633262 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.78483642 |
| 55 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78452369 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.78280175 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.74991184 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74733242 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71782845 |
| 60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.68045527 |
| 61 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.67296613 |
| 62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.64928715 |
| 63 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.64660264 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63853516 |
| 65 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.61195909 |
| 66 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60743322 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.60205761 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60088870 |
| 69 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.59418468 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57107350 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.56917425 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.55570185 |
| 73 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.55281689 |
| 74 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.54997345 |
| 75 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.54286294 |
| 76 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.53707493 |
| 77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53221188 |
| 78 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51425401 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.50814851 |
| 80 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50083032 |
| 81 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.47989884 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.46617196 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45191803 |
| 84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43096182 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42548928 |
| 86 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.41898854 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41233999 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40849320 |
| 89 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.40415291 |
| 90 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.39282228 |
| 91 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.34607270 |
| 92 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32200862 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.30739217 |
| 94 | Nicotine addiction_Homo sapiens_hsa05033 | 0.29869287 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.28763965 |
| 96 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28735200 |
| 97 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27459541 |
| 98 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.26978605 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26646898 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.24957940 |

