

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.77747288 |
| 2 | response to gravity (GO:0009629) | 5.69543682 |
| 3 | striated muscle atrophy (GO:0014891) | 4.71878212 |
| 4 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.66980188 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.61651935 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.61651935 |
| 7 | muscle atrophy (GO:0014889) | 4.47982186 |
| 8 | skeletal muscle adaptation (GO:0043501) | 4.42830112 |
| 9 | protein K6-linked ubiquitination (GO:0085020) | 4.13016118 |
| 10 | regulation of skeletal muscle contraction (GO:0014819) | 4.01279563 |
| 11 | cytidine deamination (GO:0009972) | 3.96075566 |
| 12 | cytidine metabolic process (GO:0046087) | 3.96075566 |
| 13 | cytidine catabolic process (GO:0006216) | 3.96075566 |
| 14 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.90879335 |
| 15 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.90879335 |
| 16 | negative regulation of muscle hypertrophy (GO:0014741) | 3.89189194 |
| 17 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.86446638 |
| 18 | ribosomal small subunit assembly (GO:0000028) | 3.81456902 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.72630928 |
| 20 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.66834671 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.52987050 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 3.52987050 |
| 23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.52987050 |
| 24 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.50652005 |
| 25 | chaperone-mediated protein transport (GO:0072321) | 3.47317720 |
| 26 | proteasome assembly (GO:0043248) | 3.46439211 |
| 27 | protein complex biogenesis (GO:0070271) | 3.40441072 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.38488296 |
| 29 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.36395782 |
| 30 | GTP biosynthetic process (GO:0006183) | 3.34089152 |
| 31 | response to muscle activity (GO:0014850) | 3.32817835 |
| 32 | regulation of immunoglobulin secretion (GO:0051023) | 3.32317567 |
| 33 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.27865349 |
| 34 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.26561829 |
| 35 | rRNA modification (GO:0000154) | 3.26288242 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.22506546 |
| 37 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.21371682 |
| 38 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.15668687 |
| 39 | pseudouridine synthesis (GO:0001522) | 3.14707635 |
| 40 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.11391002 |
| 41 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.11391002 |
| 42 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.11391002 |
| 43 | rRNA processing (GO:0006364) | 3.09291358 |
| 44 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.05808227 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.05808227 |
| 46 | fucose catabolic process (GO:0019317) | 3.05486653 |
| 47 | L-fucose metabolic process (GO:0042354) | 3.05486653 |
| 48 | L-fucose catabolic process (GO:0042355) | 3.05486653 |
| 49 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.05356738 |
| 50 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.04766762 |
| 51 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.04190823 |
| 52 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.04190823 |
| 53 | GDP-mannose metabolic process (GO:0019673) | 3.03551741 |
| 54 | rRNA metabolic process (GO:0016072) | 3.02239180 |
| 55 | behavioral response to nicotine (GO:0035095) | 3.01451666 |
| 56 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.00659444 |
| 57 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.99944567 |
| 58 | actin-myosin filament sliding (GO:0033275) | 2.99823536 |
| 59 | muscle filament sliding (GO:0030049) | 2.99823536 |
| 60 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.95522125 |
| 61 | cellular ketone body metabolic process (GO:0046950) | 2.93150865 |
| 62 | positive regulation of prostaglandin secretion (GO:0032308) | 2.91057926 |
| 63 | regulation of regulatory T cell differentiation (GO:0045589) | 2.90444602 |
| 64 | protein deneddylation (GO:0000338) | 2.89995886 |
| 65 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.89234875 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.89234875 |
| 67 | skeletal muscle tissue regeneration (GO:0043403) | 2.88304077 |
| 68 | rRNA methylation (GO:0031167) | 2.87802326 |
| 69 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.87111209 |
| 70 | negative regulation of ligase activity (GO:0051352) | 2.87111209 |
| 71 | protein polyglutamylation (GO:0018095) | 2.84831834 |
| 72 | ATP biosynthetic process (GO:0006754) | 2.83343064 |
| 73 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.82362423 |
| 74 | protein neddylation (GO:0045116) | 2.82274083 |
| 75 | respiratory chain complex IV assembly (GO:0008535) | 2.80411915 |
| 76 | interferon-gamma production (GO:0032609) | 2.79415999 |
| 77 | ribosomal large subunit biogenesis (GO:0042273) | 2.77317615 |
| 78 | maturation of 5.8S rRNA (GO:0000460) | 2.77099264 |
| 79 | positive regulation of defense response to virus by host (GO:0002230) | 2.75543004 |
| 80 | cullin deneddylation (GO:0010388) | 2.73235175 |
| 81 | UTP biosynthetic process (GO:0006228) | 2.73166057 |
| 82 | negative regulation of skeletal muscle tissue development (GO:0048642) | 2.70841053 |
| 83 | UTP metabolic process (GO:0046051) | 2.70112444 |
| 84 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.69810217 |
| 85 | ribosome biogenesis (GO:0042254) | 2.66945216 |
| 86 | sulfation (GO:0051923) | 2.65708076 |
| 87 | cellular component biogenesis (GO:0044085) | 2.65649559 |
| 88 | ketone body metabolic process (GO:1902224) | 2.63918441 |
| 89 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.63087011 |
| 90 | piRNA metabolic process (GO:0034587) | 2.62805401 |
| 91 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.60456209 |
| 92 | xenobiotic catabolic process (GO:0042178) | 2.58040052 |
| 93 | platelet dense granule organization (GO:0060155) | 2.57334237 |
| 94 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.56578838 |
| 95 | positive regulation of cell cycle arrest (GO:0071158) | 2.56445621 |
| 96 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.55502422 |
| 97 | translation (GO:0006412) | 2.55465839 |
| 98 | tRNA processing (GO:0008033) | 2.55268595 |
| 99 | cytochrome complex assembly (GO:0017004) | 2.53325238 |
| 100 | retina homeostasis (GO:0001895) | 2.51119419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.24989380 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 4.96851553 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.98840336 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.96584023 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.63927900 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.39440060 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.28525612 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.21290201 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.66318953 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62968632 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.47540755 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.44856468 |
| 13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.42267290 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.40331332 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.29348472 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.23784592 |
| 17 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.16421335 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.02144746 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96825791 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.96396299 |
| 21 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.95571395 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.92729650 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.90662232 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.90481707 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.82392926 |
| 26 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.77014631 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.70566684 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.70472270 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.69493692 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.69215887 |
| 31 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.64767872 |
| 32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.62168382 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60060762 |
| 34 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.58083278 |
| 35 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.56716118 |
| 36 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53964621 |
| 37 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49677231 |
| 38 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.45636419 |
| 39 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.45445798 |
| 40 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.44383692 |
| 41 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.42968113 |
| 42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.42433766 |
| 43 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.39741612 |
| 44 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.39388246 |
| 45 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.39067686 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38876722 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33019300 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.32087414 |
| 49 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.31515254 |
| 50 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.26883634 |
| 51 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.25412363 |
| 52 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.24145885 |
| 53 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.23712058 |
| 54 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23171453 |
| 55 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.19794316 |
| 56 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.18104501 |
| 57 | AR_20517297_ChIP-Seq_VCAP_Human | 1.17153383 |
| 58 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16615940 |
| 59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.16612959 |
| 60 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.16515869 |
| 61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.16014899 |
| 62 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.12535688 |
| 63 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.11523418 |
| 64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.10893966 |
| 65 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.10279936 |
| 66 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.07495230 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.06967418 |
| 68 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.06405041 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.06405041 |
| 70 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.05387001 |
| 71 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03337948 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03328362 |
| 73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03328362 |
| 74 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.98769940 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.98108210 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.97607330 |
| 77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97048927 |
| 78 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.96951535 |
| 79 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96788316 |
| 80 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96525263 |
| 81 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95655783 |
| 82 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95655783 |
| 83 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95335408 |
| 84 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.94484222 |
| 85 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94054395 |
| 86 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.93473228 |
| 87 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92669598 |
| 88 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.91739724 |
| 89 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.91515528 |
| 90 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.91200363 |
| 91 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90136105 |
| 92 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.89424797 |
| 93 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.88635795 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88580477 |
| 95 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.87974155 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.87183221 |
| 97 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.84286533 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.83989749 |
| 99 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.80758940 |
| 100 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.80537656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 3.61119414 |
| 2 | MP0004145_abnormal_muscle_electrophysio | 3.11846579 |
| 3 | MP0002638_abnormal_pupillary_reflex | 2.95055101 |
| 4 | MP0002102_abnormal_ear_morphology | 2.77581962 |
| 5 | MP0005671_abnormal_response_to | 2.71472823 |
| 6 | MP0005360_urolithiasis | 2.54425465 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.42618404 |
| 8 | MP0004147_increased_porphyrin_level | 2.42297679 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.41088143 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.38219180 |
| 11 | MP0003646_muscle_fatigue | 2.33609845 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 2.26119744 |
| 13 | MP0005084_abnormal_gallbladder_morpholo | 2.22950697 |
| 14 | MP0000747_muscle_weakness | 2.20117197 |
| 15 | MP0008872_abnormal_physiological_respon | 2.19070624 |
| 16 | MP0002139_abnormal_hepatobiliary_system | 2.09951779 |
| 17 | MP0008877_abnormal_DNA_methylation | 2.05440716 |
| 18 | MP0003195_calcinosis | 2.02053156 |
| 19 | MP0005085_abnormal_gallbladder_physiolo | 2.01076965 |
| 20 | MP0000685_abnormal_immune_system | 1.87533097 |
| 21 | MP0003786_premature_aging | 1.85947394 |
| 22 | MP0002736_abnormal_nociception_after | 1.80370180 |
| 23 | MP0005167_abnormal_blood-brain_barrier | 1.80092037 |
| 24 | MP0000372_irregular_coat_pigmentation | 1.77799662 |
| 25 | MP0003718_maternal_effect | 1.76831530 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.76584944 |
| 27 | MP0003252_abnormal_bile_duct | 1.70441920 |
| 28 | MP0002876_abnormal_thyroid_physiology | 1.69024894 |
| 29 | MP0004885_abnormal_endolymph | 1.64573212 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.63820243 |
| 31 | MP0001873_stomach_inflammation | 1.63648388 |
| 32 | MP0002089_abnormal_postnatal_growth/wei | 1.62408103 |
| 33 | MP0003283_abnormal_digestive_organ | 1.60446340 |
| 34 | MP0002148_abnormal_hypersensitivity_rea | 1.55920121 |
| 35 | MP0004036_abnormal_muscle_relaxation | 1.52524263 |
| 36 | MP0001790_abnormal_immune_system | 1.46790444 |
| 37 | MP0005387_immune_system_phenotype | 1.46790444 |
| 38 | MP0005083_abnormal_biliary_tract | 1.43161407 |
| 39 | MP0005551_abnormal_eye_electrophysiolog | 1.41970065 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.40439010 |
| 41 | MP0005253_abnormal_eye_physiology | 1.31650818 |
| 42 | MP0008058_abnormal_DNA_repair | 1.30910800 |
| 43 | MP0004043_abnormal_pH_regulation | 1.29307640 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.27355004 |
| 45 | MP0006292_abnormal_olfactory_placode | 1.27294594 |
| 46 | MP0003959_abnormal_lean_body | 1.23020989 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.20144931 |
| 48 | MP0000427_abnormal_hair_cycle | 1.19501631 |
| 49 | MP0001800_abnormal_humoral_immune | 1.18650274 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.17522519 |
| 51 | MP0009764_decreased_sensitivity_to | 1.15432615 |
| 52 | MP0001348_abnormal_lacrimal_gland | 1.14123677 |
| 53 | MP0009333_abnormal_splenocyte_physiolog | 1.10786736 |
| 54 | MP0002166_altered_tumor_susceptibility | 1.10573464 |
| 55 | MP0004142_abnormal_muscle_tone | 1.08442395 |
| 56 | MP0004019_abnormal_vitamin_homeostasis | 1.06254674 |
| 57 | MP0009785_altered_susceptibility_to | 1.02240996 |
| 58 | MP0006036_abnormal_mitochondrial_physio | 1.01562104 |
| 59 | MP0002269_muscular_atrophy | 1.01177184 |
| 60 | MP0001905_abnormal_dopamine_level | 1.00842551 |
| 61 | MP0005636_abnormal_mineral_homeostasis | 1.00133149 |
| 62 | MP0001986_abnormal_taste_sensitivity | 0.99784756 |
| 63 | MP0002006_tumorigenesis | 0.99438881 |
| 64 | MP0005389_reproductive_system_phenotype | 0.97087848 |
| 65 | MP0003866_abnormal_defecation | 0.97044834 |
| 66 | MP0005000_abnormal_immune_tolerance | 0.95798187 |
| 67 | MP0005332_abnormal_amino_acid | 0.92915497 |
| 68 | MP0004957_abnormal_blastocyst_morpholog | 0.92899259 |
| 69 | MP0001661_extended_life_span | 0.92887870 |
| 70 | MP0002723_abnormal_immune_serum | 0.92277448 |
| 71 | MP0002095_abnormal_skin_pigmentation | 0.90981989 |
| 72 | MP0008995_early_reproductive_senescence | 0.90775125 |
| 73 | MP0000013_abnormal_adipose_tissue | 0.90351916 |
| 74 | MP0002160_abnormal_reproductive_system | 0.89939509 |
| 75 | MP0005365_abnormal_bile_salt | 0.89379594 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.86862194 |
| 77 | MP0001765_abnormal_ion_homeostasis | 0.84367345 |
| 78 | MP0001666_abnormal_nutrient_absorption | 0.83214265 |
| 79 | MP0003937_abnormal_limbs/digits/tail_de | 0.82767442 |
| 80 | MP0005075_abnormal_melanosome_morpholog | 0.82283244 |
| 81 | MP0001919_abnormal_reproductive_system | 0.81783999 |
| 82 | MP0002938_white_spotting | 0.81456296 |
| 83 | MP0004215_abnormal_myocardial_fiber | 0.80594860 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.80588697 |
| 85 | MP0002106_abnormal_muscle_physiology | 0.79925086 |
| 86 | MP0010329_abnormal_lipoprotein_level | 0.78130394 |
| 87 | MP0001764_abnormal_homeostasis | 0.77586026 |
| 88 | MP0000631_abnormal_neuroendocrine_gland | 0.75873315 |
| 89 | MP0002420_abnormal_adaptive_immunity | 0.75330271 |
| 90 | MP0000465_gastrointestinal_hemorrhage | 0.74493062 |
| 91 | MP0001819_abnormal_immune_cell | 0.72936069 |
| 92 | MP0000569_abnormal_digit_pigmentation | 0.72837706 |
| 93 | MP0005646_abnormal_pituitary_gland | 0.72238166 |
| 94 | MP0001529_abnormal_vocalization | 0.71933839 |
| 95 | MP0003724_increased_susceptibility_to | 0.71628478 |
| 96 | MP0005620_abnormal_muscle_contractility | 0.71276466 |
| 97 | MP0002693_abnormal_pancreas_physiology | 0.69607275 |
| 98 | MP0001119_abnormal_female_reproductive | 0.68560775 |
| 99 | MP0003011_delayed_dark_adaptation | 0.68012541 |
| 100 | MP0002272_abnormal_nervous_system | 0.67927548 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Palpebral edema (HP:0100540) | 3.67351162 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 3.53226539 |
| 3 | 3-Methylglutaconic aciduria (HP:0003535) | 3.41567777 |
| 4 | Increased CSF lactate (HP:0002490) | 3.34226978 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.31489936 |
| 6 | Acute encephalopathy (HP:0006846) | 3.25571089 |
| 7 | Congenital stationary night blindness (HP:0007642) | 3.22422122 |
| 8 | Absent phalangeal crease (HP:0006109) | 3.20435820 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.12163288 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.07454891 |
| 11 | Hepatic necrosis (HP:0002605) | 3.05181826 |
| 12 | IgG deficiency (HP:0004315) | 3.01027470 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 2.96616984 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.92097753 |
| 15 | Abnormality of the renal cortex (HP:0011035) | 2.91530455 |
| 16 | Stomatitis (HP:0010280) | 2.89157727 |
| 17 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.84403537 |
| 18 | Abnormality of alanine metabolism (HP:0010916) | 2.84403537 |
| 19 | Hyperalaninemia (HP:0003348) | 2.84403537 |
| 20 | Hepatocellular necrosis (HP:0001404) | 2.81773945 |
| 21 | Distal arthrogryposis (HP:0005684) | 2.81753643 |
| 22 | Methylmalonic acidemia (HP:0002912) | 2.79325736 |
| 23 | Renal cortical cysts (HP:0000803) | 2.72813239 |
| 24 | Abolished electroretinogram (ERG) (HP:0000550) | 2.69073067 |
| 25 | Abnormal finger flexion creases (HP:0006143) | 2.67826484 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.64898672 |
| 27 | Increased serum lactate (HP:0002151) | 2.64745703 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.62775819 |
| 29 | Decreased circulating renin level (HP:0003351) | 2.62620921 |
| 30 | Methylmalonic aciduria (HP:0012120) | 2.59421364 |
| 31 | Ulnar deviation of the wrist (HP:0003049) | 2.58635217 |
| 32 | Pancreatic cysts (HP:0001737) | 2.57326488 |
| 33 | Round ear (HP:0100830) | 2.56804845 |
| 34 | Delayed CNS myelination (HP:0002188) | 2.55008847 |
| 35 | Cerebral edema (HP:0002181) | 2.54112327 |
| 36 | Abnormality of urine glucose concentration (HP:0011016) | 2.53339257 |
| 37 | Glycosuria (HP:0003076) | 2.53339257 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.47786487 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.41508698 |
| 40 | Molar tooth sign on MRI (HP:0002419) | 2.41508698 |
| 41 | Hypoplasia of the pons (HP:0012110) | 2.40069849 |
| 42 | Abnormality of the pons (HP:0007361) | 2.37649255 |
| 43 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.36840763 |
| 44 | Nephronophthisis (HP:0000090) | 2.34277019 |
| 45 | Optic disc pallor (HP:0000543) | 2.28321960 |
| 46 | Dicarboxylic aciduria (HP:0003215) | 2.28264744 |
| 47 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.28264744 |
| 48 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.27957202 |
| 49 | Lactic acidosis (HP:0003128) | 2.27124845 |
| 50 | Nemaline bodies (HP:0003798) | 2.26512655 |
| 51 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.24998324 |
| 52 | Metabolic acidosis (HP:0001942) | 2.23286217 |
| 53 | Colon cancer (HP:0003003) | 2.23233844 |
| 54 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.19313389 |
| 55 | Abnormality of the renal medulla (HP:0100957) | 2.18124933 |
| 56 | Lethargy (HP:0001254) | 2.17793355 |
| 57 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.17165156 |
| 58 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.16626725 |
| 59 | Hypoglycemic coma (HP:0001325) | 2.12909341 |
| 60 | Pancreatic fibrosis (HP:0100732) | 2.10855458 |
| 61 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.10210944 |
| 62 | Hyperglycinemia (HP:0002154) | 2.08866491 |
| 63 | Abnormality of vitamin B metabolism (HP:0004340) | 2.08151516 |
| 64 | Generalized aminoaciduria (HP:0002909) | 2.07962893 |
| 65 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.07902336 |
| 66 | Abnormality of the prostate (HP:0008775) | 2.04962339 |
| 67 | Hypobetalipoproteinemia (HP:0003563) | 2.04812124 |
| 68 | Hypoproteinemia (HP:0003075) | 2.03626235 |
| 69 | True hermaphroditism (HP:0010459) | 2.01797420 |
| 70 | Type II lissencephaly (HP:0007260) | 2.00074272 |
| 71 | Abnormality of serum amino acid levels (HP:0003112) | 1.99708874 |
| 72 | Prostate neoplasm (HP:0100787) | 1.97589040 |
| 73 | Exertional dyspnea (HP:0002875) | 1.95762975 |
| 74 | Type I transferrin isoform profile (HP:0003642) | 1.93420419 |
| 75 | Attenuation of retinal blood vessels (HP:0007843) | 1.91194921 |
| 76 | Hypoplasia of the uterus (HP:0000013) | 1.90094011 |
| 77 | Chorioretinal atrophy (HP:0000533) | 1.89449426 |
| 78 | Abnormality of methionine metabolism (HP:0010901) | 1.88170840 |
| 79 | Decreased central vision (HP:0007663) | 1.87524839 |
| 80 | Abnormality of macular pigmentation (HP:0008002) | 1.85582775 |
| 81 | Pendular nystagmus (HP:0012043) | 1.84666994 |
| 82 | Mask-like facies (HP:0000298) | 1.83754909 |
| 83 | Stomach cancer (HP:0012126) | 1.83179215 |
| 84 | Abnormal biliary tract physiology (HP:0012439) | 1.83026687 |
| 85 | Bile duct proliferation (HP:0001408) | 1.83026687 |
| 86 | Abnormal drinking behavior (HP:0030082) | 1.82721924 |
| 87 | Polydipsia (HP:0001959) | 1.82721924 |
| 88 | Confusion (HP:0001289) | 1.81374569 |
| 89 | Alkalosis (HP:0001948) | 1.80976440 |
| 90 | Abnormality of the labia minora (HP:0012880) | 1.79663885 |
| 91 | Oral leukoplakia (HP:0002745) | 1.76032403 |
| 92 | Periorbital edema (HP:0100539) | 1.75614342 |
| 93 | Respiratory failure (HP:0002878) | 1.75167047 |
| 94 | Abnormal albumin level (HP:0012116) | 1.74902629 |
| 95 | Hypoalbuminemia (HP:0003073) | 1.74902629 |
| 96 | Reticulocytopenia (HP:0001896) | 1.74560917 |
| 97 | Metabolic alkalosis (HP:0200114) | 1.74413181 |
| 98 | Conjunctival hamartoma (HP:0100780) | 1.73559911 |
| 99 | Exercise intolerance (HP:0003546) | 1.72797546 |
| 100 | Absent thumb (HP:0009777) | 1.72585130 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 4.27166726 |
| 2 | TLK1 | 4.09045730 |
| 3 | NUAK1 | 3.44288360 |
| 4 | VRK2 | 3.09725136 |
| 5 | TXK | 3.09539584 |
| 6 | TIE1 | 2.75881462 |
| 7 | MAP4K2 | 2.42708314 |
| 8 | FRK | 2.26053251 |
| 9 | WNK4 | 2.18206279 |
| 10 | VRK1 | 2.17458105 |
| 11 | ADRBK2 | 1.99860522 |
| 12 | GRK1 | 1.97468649 |
| 13 | MST4 | 1.96404044 |
| 14 | TAF1 | 1.93093698 |
| 15 | PHKG2 | 1.92039587 |
| 16 | PHKG1 | 1.92039587 |
| 17 | BUB1 | 1.83703740 |
| 18 | TSSK6 | 1.75374815 |
| 19 | TAOK3 | 1.71012521 |
| 20 | STK16 | 1.66487282 |
| 21 | EIF2AK3 | 1.63797180 |
| 22 | PINK1 | 1.61310390 |
| 23 | PASK | 1.47592279 |
| 24 | BMPR1B | 1.42810492 |
| 25 | BCKDK | 1.33255028 |
| 26 | OBSCN | 1.31514671 |
| 27 | SRPK1 | 1.30065528 |
| 28 | CAMKK2 | 1.22371965 |
| 29 | FES | 1.21968597 |
| 30 | TEC | 1.20435577 |
| 31 | CSNK1G3 | 1.17639200 |
| 32 | CSNK1G1 | 1.10661185 |
| 33 | PBK | 1.09986372 |
| 34 | TRIM28 | 1.06956944 |
| 35 | PLK3 | 1.01446281 |
| 36 | CSNK1G2 | 0.99871222 |
| 37 | MAP2K6 | 0.96440021 |
| 38 | STK39 | 0.93488717 |
| 39 | MAP4K1 | 0.92397644 |
| 40 | EIF2AK2 | 0.92161750 |
| 41 | RPS6KA5 | 0.92106176 |
| 42 | MAP3K12 | 0.92042082 |
| 43 | IKBKB | 0.90478545 |
| 44 | ACVR1B | 0.89398546 |
| 45 | PIK3CG | 0.87971233 |
| 46 | ITK | 0.86121574 |
| 47 | NME1 | 0.86047825 |
| 48 | CSNK1A1L | 0.85551884 |
| 49 | NME2 | 0.85334161 |
| 50 | OXSR1 | 0.84051832 |
| 51 | PDK2 | 0.83058016 |
| 52 | FER | 0.82873351 |
| 53 | TGFBR1 | 0.81485984 |
| 54 | MKNK1 | 0.81070833 |
| 55 | WNK3 | 0.76791832 |
| 56 | IRAK1 | 0.75383249 |
| 57 | TNIK | 0.74658478 |
| 58 | EIF2AK1 | 0.74178581 |
| 59 | NLK | 0.72363832 |
| 60 | DAPK1 | 0.72074134 |
| 61 | INSRR | 0.71587903 |
| 62 | MKNK2 | 0.67247035 |
| 63 | DYRK2 | 0.63211299 |
| 64 | JAK3 | 0.63087778 |
| 65 | CHEK2 | 0.62974838 |
| 66 | PRKCQ | 0.57817819 |
| 67 | KIT | 0.57670606 |
| 68 | MAPK13 | 0.57006338 |
| 69 | AURKA | 0.53424678 |
| 70 | FGFR2 | 0.53189762 |
| 71 | MAP3K4 | 0.52255804 |
| 72 | MAP2K2 | 0.51869254 |
| 73 | ATR | 0.50986743 |
| 74 | PIK3CA | 0.50022497 |
| 75 | MAP3K14 | 0.47230523 |
| 76 | STK4 | 0.46361525 |
| 77 | SYK | 0.45271176 |
| 78 | MAPKAPK5 | 0.43734091 |
| 79 | MAP2K7 | 0.41823218 |
| 80 | CCNB1 | 0.41812017 |
| 81 | GRK6 | 0.37621996 |
| 82 | ERBB3 | 0.37461547 |
| 83 | CSNK1A1 | 0.35470959 |
| 84 | MYLK | 0.34561983 |
| 85 | WNK1 | 0.33926092 |
| 86 | DAPK3 | 0.33651540 |
| 87 | EPHA3 | 0.33182853 |
| 88 | ALK | 0.32660804 |
| 89 | CSNK2A1 | 0.31963913 |
| 90 | CHUK | 0.31941291 |
| 91 | LCK | 0.31641164 |
| 92 | IGF1R | 0.30683935 |
| 93 | PRKCA | 0.30154824 |
| 94 | ADRBK1 | 0.30130401 |
| 95 | PRKACA | 0.29987257 |
| 96 | STK3 | 0.29308454 |
| 97 | PRKCG | 0.29301432 |
| 98 | NEK1 | 0.29044419 |
| 99 | PLK1 | 0.28847559 |
| 100 | MAPKAPK3 | 0.28624117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.08579887 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.01595365 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 2.84160247 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.48987591 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.43352578 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.38734952 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.28836632 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.25004062 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.15217338 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.01939211 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.98383299 |
| 12 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.95325358 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.92870859 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.86982780 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.85777792 |
| 16 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.85682103 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.84376418 |
| 18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.82755094 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.80501571 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.56662895 |
| 21 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.56452599 |
| 22 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.54686417 |
| 23 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.41393560 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.39988329 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37788178 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.37334142 |
| 27 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.33717353 |
| 28 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.33603121 |
| 29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.32294614 |
| 30 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.31581497 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.30050121 |
| 32 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.29749828 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.28792493 |
| 34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.22634502 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.21533518 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.20968436 |
| 37 | Alzheimers disease_Homo sapiens_hsa05010 | 1.20209503 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.19000395 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.18103422 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17618687 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.17079692 |
| 42 | Huntingtons disease_Homo sapiens_hsa05016 | 1.13686028 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.12697930 |
| 44 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.11678908 |
| 45 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.10394134 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 1.09368127 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.05114782 |
| 48 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.04832688 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03233883 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 1.02286506 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 1.01631886 |
| 52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00007015 |
| 53 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.93988884 |
| 54 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.93643773 |
| 55 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.92900571 |
| 56 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.91044491 |
| 57 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89868444 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89197607 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.86310120 |
| 60 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.84953325 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84828458 |
| 62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83367913 |
| 63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.81024439 |
| 64 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.80756462 |
| 65 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.78895346 |
| 66 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78451095 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.76333140 |
| 68 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.72660187 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72288412 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70330921 |
| 71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.66600136 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61808560 |
| 73 | DNA replication_Homo sapiens_hsa03030 | 0.58870593 |
| 74 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.57023305 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56040425 |
| 76 | Alcoholism_Homo sapiens_hsa05034 | 0.54841056 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.52455791 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.49792047 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.48938124 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.46902027 |
| 81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46241633 |
| 82 | Tight junction_Homo sapiens_hsa04530 | 0.45508045 |
| 83 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.45003532 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44566256 |
| 85 | Mineral absorption_Homo sapiens_hsa04978 | 0.41644975 |
| 86 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41600972 |
| 87 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.40179028 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.39986757 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39001446 |
| 90 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38830994 |
| 91 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36574290 |
| 92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36290182 |
| 93 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33844935 |
| 94 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.31555942 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.31002479 |
| 96 | Carbon metabolism_Homo sapiens_hsa01200 | 0.30137905 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29374594 |
| 98 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.29195497 |
| 99 | Viral myocarditis_Homo sapiens_hsa05416 | 0.29180157 |
| 100 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.28083312 |

