

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of 5.8S rRNA (GO:0000460) | 5.63900180 |
| 2 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 5.57988291 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.43080169 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 5.19976375 |
| 5 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.95877027 |
| 6 | piRNA metabolic process (GO:0034587) | 4.94075125 |
| 7 | rRNA modification (GO:0000154) | 4.61059512 |
| 8 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 4.57104166 |
| 9 | cytochrome complex assembly (GO:0017004) | 4.49060441 |
| 10 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.48435071 |
| 11 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 4.45617749 |
| 12 | DNA deamination (GO:0045006) | 4.36390308 |
| 13 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 4.32283543 |
| 14 | pseudouridine synthesis (GO:0001522) | 4.28425319 |
| 15 | RNA localization (GO:0006403) | 4.25325778 |
| 16 | ribosomal small subunit biogenesis (GO:0042274) | 4.14318085 |
| 17 | megakaryocyte development (GO:0035855) | 4.12414374 |
| 18 | behavioral response to nicotine (GO:0035095) | 4.02652725 |
| 19 | proteasome assembly (GO:0043248) | 3.99103995 |
| 20 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.98345631 |
| 21 | positive regulation of translational initiation (GO:0045948) | 3.97967483 |
| 22 | protein complex biogenesis (GO:0070271) | 3.97540715 |
| 23 | GTP biosynthetic process (GO:0006183) | 3.97459687 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.92412458 |
| 25 | ATP synthesis coupled proton transport (GO:0015986) | 3.92412458 |
| 26 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.89940425 |
| 27 | viral transcription (GO:0019083) | 3.85361874 |
| 28 | translational termination (GO:0006415) | 3.77188484 |
| 29 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.71474609 |
| 30 | respiratory chain complex IV assembly (GO:0008535) | 3.67675841 |
| 31 | secretory granule organization (GO:0033363) | 3.64645447 |
| 32 | signal complex assembly (GO:0007172) | 3.62681442 |
| 33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.56608927 |
| 34 | cotranslational protein targeting to membrane (GO:0006613) | 3.51358417 |
| 35 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.50256852 |
| 36 | protein targeting to ER (GO:0045047) | 3.48822568 |
| 37 | rRNA methylation (GO:0031167) | 3.46497943 |
| 38 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.45990371 |
| 39 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.45990371 |
| 40 | regulation of regulatory T cell differentiation (GO:0045589) | 3.44674235 |
| 41 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 3.42327829 |
| 42 | regulation of immunoglobulin secretion (GO:0051023) | 3.37043500 |
| 43 | translation (GO:0006412) | 3.35361864 |
| 44 | regulation of mitochondrial translation (GO:0070129) | 3.34664888 |
| 45 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.32988908 |
| 46 | protein localization to endoplasmic reticulum (GO:0070972) | 3.31809531 |
| 47 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.31698954 |
| 48 | translational elongation (GO:0006414) | 3.27928574 |
| 49 | UTP biosynthetic process (GO:0006228) | 3.27514794 |
| 50 | cullin deneddylation (GO:0010388) | 3.27361723 |
| 51 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.25988075 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.24301962 |
| 53 | translational initiation (GO:0006413) | 3.17783906 |
| 54 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 3.16189240 |
| 55 | chaperone-mediated protein transport (GO:0072321) | 3.14307528 |
| 56 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 3.12967604 |
| 57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.12321916 |
| 58 | termination of RNA polymerase III transcription (GO:0006386) | 3.12321916 |
| 59 | signal peptide processing (GO:0006465) | 3.11810398 |
| 60 | cellular component biogenesis (GO:0044085) | 3.09330791 |
| 61 | protein neddylation (GO:0045116) | 3.08377878 |
| 62 | regulation of chronic inflammatory response (GO:0002676) | 3.06683883 |
| 63 | peptidyl-histidine modification (GO:0018202) | 3.05737901 |
| 64 | platelet dense granule organization (GO:0060155) | 3.02516678 |
| 65 | rRNA metabolic process (GO:0016072) | 2.94982879 |
| 66 | rRNA processing (GO:0006364) | 2.94730476 |
| 67 | protein deneddylation (GO:0000338) | 2.94065294 |
| 68 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.89448742 |
| 69 | response to pheromone (GO:0019236) | 2.86838800 |
| 70 | protein peptidyl-prolyl isomerization (GO:0000413) | 2.85995523 |
| 71 | DNA methylation involved in gamete generation (GO:0043046) | 2.84922667 |
| 72 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.83566765 |
| 73 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.83005591 |
| 74 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.83005591 |
| 75 | NADH dehydrogenase complex assembly (GO:0010257) | 2.83005591 |
| 76 | cellular protein complex disassembly (GO:0043624) | 2.81641652 |
| 77 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.80177471 |
| 78 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.79691154 |
| 79 | ribosomal large subunit biogenesis (GO:0042273) | 2.79268763 |
| 80 | positive regulation of interleukin-17 production (GO:0032740) | 2.79111976 |
| 81 | viral life cycle (GO:0019058) | 2.77184847 |
| 82 | UTP metabolic process (GO:0046051) | 2.76900156 |
| 83 | electron transport chain (GO:0022900) | 2.74767314 |
| 84 | positive regulation of isotype switching (GO:0045830) | 2.71880852 |
| 85 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.70679014 |
| 86 | maturation of SSU-rRNA (GO:0030490) | 2.70221451 |
| 87 | respiratory electron transport chain (GO:0022904) | 2.69741088 |
| 88 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.65575736 |
| 89 | intracellular protein transmembrane import (GO:0044743) | 2.64249272 |
| 90 | regulation of meiosis I (GO:0060631) | 2.63217163 |
| 91 | negative regulation of translational initiation (GO:0045947) | 2.61237819 |
| 92 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.60810139 |
| 93 | positive regulation of DNA recombination (GO:0045911) | 2.60801479 |
| 94 | male meiosis I (GO:0007141) | 2.59646954 |
| 95 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.55309600 |
| 96 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.54743028 |
| 97 | CTP metabolic process (GO:0046036) | 2.54418032 |
| 98 | CTP biosynthetic process (GO:0006241) | 2.54418032 |
| 99 | ribosome biogenesis (GO:0042254) | 2.54415540 |
| 100 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.53154527 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.81572014 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.25777599 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.04852665 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.91258145 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.29501289 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.01661380 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.97032629 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.78908806 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.70876198 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56477480 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.54587452 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.52616257 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.44172700 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.35288672 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25801696 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.09994854 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.06994522 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03824314 |
| 19 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.00497013 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.95243433 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.92241928 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.89910837 |
| 23 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.88121345 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.81051128 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.78640518 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.69082443 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.68570777 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.67937225 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59365597 |
| 30 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.52916181 |
| 31 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.52027787 |
| 32 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.48382048 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.47382684 |
| 34 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.43866631 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.43165767 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.43021925 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.42910845 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.42910845 |
| 39 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36362005 |
| 40 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36362005 |
| 41 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.33679188 |
| 42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.30735128 |
| 43 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.28960094 |
| 44 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27250048 |
| 45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.23542314 |
| 46 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.23216773 |
| 47 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.22194962 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22041259 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.21797409 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20921863 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.19956054 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.17120955 |
| 53 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14476887 |
| 54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.14115357 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.12029203 |
| 56 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.11243156 |
| 57 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.10916509 |
| 58 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10713507 |
| 59 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10239438 |
| 60 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.09668683 |
| 61 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08605138 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.08132889 |
| 63 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.06596500 |
| 64 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.06447302 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05777291 |
| 66 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03868323 |
| 67 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.03779216 |
| 68 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02907369 |
| 69 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.01984391 |
| 70 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.01768515 |
| 71 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.01629910 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01188030 |
| 73 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01135319 |
| 74 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.01043631 |
| 75 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.00674853 |
| 76 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.00660944 |
| 77 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00210089 |
| 78 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.99951147 |
| 79 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.98467019 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98047930 |
| 81 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.97032551 |
| 82 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.96895355 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.96818025 |
| 84 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.96757520 |
| 85 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96402769 |
| 86 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.96082741 |
| 87 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96064485 |
| 88 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.95262846 |
| 89 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.94500288 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.93178366 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.92570430 |
| 92 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.92526462 |
| 93 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.92132243 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.90972982 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88997464 |
| 96 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88638070 |
| 97 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.88108734 |
| 98 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.87902903 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.86986600 |
| 100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.86630216 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 3.68072385 |
| 2 | MP0002102_abnormal_ear_morphology | 3.27531413 |
| 3 | MP0000372_irregular_coat_pigmentation | 3.27167998 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.15695870 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.60100137 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.58702958 |
| 7 | MP0008872_abnormal_physiological_respon | 2.35394842 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 2.32958567 |
| 9 | MP0005646_abnormal_pituitary_gland | 2.12522174 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.09791382 |
| 11 | MP0009379_abnormal_foot_pigmentation | 2.04232123 |
| 12 | MP0003718_maternal_effect | 2.01810282 |
| 13 | MP0005645_abnormal_hypothalamus_physiol | 2.01773702 |
| 14 | MP0002938_white_spotting | 2.01223928 |
| 15 | MP0005671_abnormal_response_to | 1.92449890 |
| 16 | MP0001348_abnormal_lacrimal_gland | 1.88446789 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.78538881 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.75354554 |
| 19 | MP0002876_abnormal_thyroid_physiology | 1.75018511 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.73630111 |
| 21 | MP0003878_abnormal_ear_physiology | 1.73630111 |
| 22 | MP0004885_abnormal_endolymph | 1.71516096 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.70555753 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.66193280 |
| 25 | MP0005410_abnormal_fertilization | 1.61048454 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.61025287 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.58749764 |
| 28 | MP0004147_increased_porphyrin_level | 1.55901055 |
| 29 | MP0003011_delayed_dark_adaptation | 1.55583039 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.54567346 |
| 31 | MP0003787_abnormal_imprinting | 1.47210645 |
| 32 | MP0001873_stomach_inflammation | 1.46075442 |
| 33 | MP0009333_abnormal_splenocyte_physiolog | 1.44229124 |
| 34 | MP0000685_abnormal_immune_system | 1.42782533 |
| 35 | MP0003693_abnormal_embryo_hatching | 1.41177692 |
| 36 | MP0003195_calcinosis | 1.41147398 |
| 37 | MP0006036_abnormal_mitochondrial_physio | 1.40042291 |
| 38 | MP0003186_abnormal_redox_activity | 1.39619860 |
| 39 | MP0002736_abnormal_nociception_after | 1.37138691 |
| 40 | MP0005075_abnormal_melanosome_morpholog | 1.37053357 |
| 41 | MP0009764_decreased_sensitivity_to | 1.36842143 |
| 42 | MP0008789_abnormal_olfactory_epithelium | 1.36543878 |
| 43 | MP0003786_premature_aging | 1.36494843 |
| 44 | MP0005636_abnormal_mineral_homeostasis | 1.36404497 |
| 45 | MP0008058_abnormal_DNA_repair | 1.34908228 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.34493951 |
| 47 | MP0001790_abnormal_immune_system | 1.31539410 |
| 48 | MP0005387_immune_system_phenotype | 1.31539410 |
| 49 | MP0004742_abnormal_vestibular_system | 1.28819471 |
| 50 | MP0004142_abnormal_muscle_tone | 1.27081758 |
| 51 | MP0003283_abnormal_digestive_organ | 1.26369519 |
| 52 | MP0005253_abnormal_eye_physiology | 1.19967808 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.18957213 |
| 54 | MP0005174_abnormal_tail_pigmentation | 1.18673845 |
| 55 | MP0001800_abnormal_humoral_immune | 1.18319463 |
| 56 | MP0002272_abnormal_nervous_system | 1.17427396 |
| 57 | MP0001986_abnormal_taste_sensitivity | 1.15075000 |
| 58 | MP0006276_abnormal_autonomic_nervous | 1.14973451 |
| 59 | MP0005389_reproductive_system_phenotype | 1.13194658 |
| 60 | MP0005408_hypopigmentation | 1.10256497 |
| 61 | MP0002006_tumorigenesis | 1.09147985 |
| 62 | MP0010386_abnormal_urinary_bladder | 1.07232100 |
| 63 | MP0003806_abnormal_nucleotide_metabolis | 1.06419600 |
| 64 | MP0004957_abnormal_blastocyst_morpholog | 1.06335523 |
| 65 | MP0002160_abnormal_reproductive_system | 1.04462725 |
| 66 | MP0001485_abnormal_pinna_reflex | 1.02100128 |
| 67 | MP0001984_abnormal_olfaction | 1.00587960 |
| 68 | MP0001905_abnormal_dopamine_level | 0.99856672 |
| 69 | MP0002166_altered_tumor_susceptibility | 0.98767759 |
| 70 | MP0010030_abnormal_orbit_morphology | 0.97534543 |
| 71 | MP0009785_altered_susceptibility_to | 0.96734466 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.96103533 |
| 73 | MP0001501_abnormal_sleep_pattern | 0.91031123 |
| 74 | MP0009745_abnormal_behavioral_response | 0.89344255 |
| 75 | MP0001293_anophthalmia | 0.89092935 |
| 76 | MP0009046_muscle_twitch | 0.87862458 |
| 77 | MP0001663_abnormal_digestive_system | 0.85998875 |
| 78 | MP0004133_heterotaxia | 0.85567437 |
| 79 | MP0010155_abnormal_intestine_physiology | 0.85510155 |
| 80 | MP0004019_abnormal_vitamin_homeostasis | 0.84932026 |
| 81 | MP0002210_abnormal_sex_determination | 0.84732470 |
| 82 | MP0001119_abnormal_female_reproductive | 0.84639208 |
| 83 | MP0005000_abnormal_immune_tolerance | 0.83934115 |
| 84 | MP0008775_abnormal_heart_ventricle | 0.83621428 |
| 85 | MP0004215_abnormal_myocardial_fiber | 0.82687615 |
| 86 | MP0001919_abnormal_reproductive_system | 0.81983532 |
| 87 | MP0005332_abnormal_amino_acid | 0.81154042 |
| 88 | MP0002163_abnormal_gland_morphology | 0.80669984 |
| 89 | MP0003866_abnormal_defecation | 0.80329010 |
| 90 | MP0003567_abnormal_fetal_cardiomyocyte | 0.79169713 |
| 91 | MP0003936_abnormal_reproductive_system | 0.78777313 |
| 92 | MP0002638_abnormal_pupillary_reflex | 0.77211985 |
| 93 | MP0002723_abnormal_immune_serum | 0.75242799 |
| 94 | MP0000516_abnormal_urinary_system | 0.73810473 |
| 95 | MP0005367_renal/urinary_system_phenotyp | 0.73810473 |
| 96 | MP0005394_taste/olfaction_phenotype | 0.72832500 |
| 97 | MP0005499_abnormal_olfactory_system | 0.72832500 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.72455968 |
| 99 | MP0003252_abnormal_bile_duct | 0.71938458 |
| 100 | MP0001853_heart_inflammation | 0.71359740 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.92631200 |
| 2 | Increased CSF lactate (HP:0002490) | 3.55231040 |
| 3 | Progressive macrocephaly (HP:0004481) | 3.47264986 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.44792022 |
| 5 | Acute encephalopathy (HP:0006846) | 3.41802801 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.38109182 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28780168 |
| 8 | Stomatitis (HP:0010280) | 3.18001867 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.12253491 |
| 10 | Pancreatic cysts (HP:0001737) | 3.08454343 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.94271374 |
| 12 | Cerebral hypomyelination (HP:0006808) | 2.92988509 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 2.87101140 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 2.87101140 |
| 15 | Optic disc pallor (HP:0000543) | 2.84060901 |
| 16 | Pendular nystagmus (HP:0012043) | 2.83406270 |
| 17 | Nephronophthisis (HP:0000090) | 2.81333383 |
| 18 | Reticulocytopenia (HP:0001896) | 2.81293675 |
| 19 | Renal Fanconi syndrome (HP:0001994) | 2.81239531 |
| 20 | Methylmalonic acidemia (HP:0002912) | 2.77149904 |
| 21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.69706642 |
| 22 | Attenuation of retinal blood vessels (HP:0007843) | 2.69370362 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 2.68987109 |
| 24 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67165119 |
| 25 | Hepatocellular necrosis (HP:0001404) | 2.66994854 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.63133614 |
| 27 | Exertional dyspnea (HP:0002875) | 2.56202987 |
| 28 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.55117644 |
| 29 | Asplenia (HP:0001746) | 2.53321470 |
| 30 | True hermaphroditism (HP:0010459) | 2.53155748 |
| 31 | Hypoproteinemia (HP:0003075) | 2.51302556 |
| 32 | Congenital, generalized hypertrichosis (HP:0004540) | 2.51184843 |
| 33 | Abnormality of the renal medulla (HP:0100957) | 2.46946215 |
| 34 | Congenital stationary night blindness (HP:0007642) | 2.46430416 |
| 35 | Abnormality of the labia minora (HP:0012880) | 2.43184502 |
| 36 | Increased serum lactate (HP:0002151) | 2.39993291 |
| 37 | Abnormality of the renal cortex (HP:0011035) | 2.35784811 |
| 38 | Cerebral edema (HP:0002181) | 2.35113677 |
| 39 | Hepatic necrosis (HP:0002605) | 2.34362259 |
| 40 | Aplastic anemia (HP:0001915) | 2.31295441 |
| 41 | Hyperglycinemia (HP:0002154) | 2.30519475 |
| 42 | Decreased central vision (HP:0007663) | 2.29204563 |
| 43 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.28912738 |
| 44 | Macrocytic anemia (HP:0001972) | 2.27170257 |
| 45 | Agitation (HP:0000713) | 2.26762347 |
| 46 | IgG deficiency (HP:0004315) | 2.25032499 |
| 47 | Abolished electroretinogram (ERG) (HP:0000550) | 2.23790582 |
| 48 | Methylmalonic aciduria (HP:0012120) | 2.22943369 |
| 49 | Abnormality of renal resorption (HP:0011038) | 2.21881363 |
| 50 | Abnormal biliary tract physiology (HP:0012439) | 2.20473513 |
| 51 | Bile duct proliferation (HP:0001408) | 2.20473513 |
| 52 | Medial flaring of the eyebrow (HP:0010747) | 2.18458557 |
| 53 | Adrenal hypoplasia (HP:0000835) | 2.17391147 |
| 54 | Polydipsia (HP:0001959) | 2.17210967 |
| 55 | Abnormal drinking behavior (HP:0030082) | 2.17210967 |
| 56 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16205656 |
| 57 | Type 2 muscle fiber atrophy (HP:0003554) | 2.13600929 |
| 58 | Pancytopenia (HP:0001876) | 2.12260122 |
| 59 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.12073374 |
| 60 | Supernumerary spleens (HP:0009799) | 2.11793686 |
| 61 | Lethargy (HP:0001254) | 2.09210750 |
| 62 | Colon cancer (HP:0003003) | 2.07676069 |
| 63 | Increased IgM level (HP:0003496) | 2.07495390 |
| 64 | Keratoconus (HP:0000563) | 2.04950012 |
| 65 | Increased corneal curvature (HP:0100692) | 2.04950012 |
| 66 | Hypoplasia of the uterus (HP:0000013) | 2.03289450 |
| 67 | Short tibia (HP:0005736) | 2.01041176 |
| 68 | Glycosuria (HP:0003076) | 2.00226019 |
| 69 | Abnormality of urine glucose concentration (HP:0011016) | 2.00226019 |
| 70 | Abnormality of alanine metabolism (HP:0010916) | 1.98946453 |
| 71 | Hyperalaninemia (HP:0003348) | 1.98946453 |
| 72 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.98946453 |
| 73 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.94767791 |
| 74 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.94228209 |
| 75 | Hypoplasia of the fovea (HP:0007750) | 1.94228209 |
| 76 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.91936192 |
| 77 | Polyuria (HP:0000103) | 1.90713084 |
| 78 | Testicular atrophy (HP:0000029) | 1.90049008 |
| 79 | Lactic acidosis (HP:0003128) | 1.88527825 |
| 80 | Sclerocornea (HP:0000647) | 1.87513522 |
| 81 | Abnormal ciliary motility (HP:0012262) | 1.86768654 |
| 82 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.86204631 |
| 83 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.85745604 |
| 84 | CNS demyelination (HP:0007305) | 1.85397767 |
| 85 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.85108880 |
| 86 | Leukodystrophy (HP:0002415) | 1.84371557 |
| 87 | Hypoplasia of the ulna (HP:0003022) | 1.83649005 |
| 88 | Tubular atrophy (HP:0000092) | 1.83594573 |
| 89 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.82993668 |
| 90 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.81255186 |
| 91 | Large for gestational age (HP:0001520) | 1.81038225 |
| 92 | Stenosis of the external auditory canal (HP:0000402) | 1.79014965 |
| 93 | Alveolar cell carcinoma (HP:0006519) | 1.78874363 |
| 94 | Pallor (HP:0000980) | 1.78783707 |
| 95 | Abnormality of the ileum (HP:0001549) | 1.78332054 |
| 96 | Meckel diverticulum (HP:0002245) | 1.78209314 |
| 97 | Respiratory failure (HP:0002878) | 1.77390566 |
| 98 | IgM deficiency (HP:0002850) | 1.77126333 |
| 99 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.74501429 |
| 100 | Respiratory difficulties (HP:0002880) | 1.74186557 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK1 | 4.58879343 |
| 2 | BMPR2 | 3.55009959 |
| 3 | NUAK1 | 2.89240945 |
| 4 | TIE1 | 2.64313336 |
| 5 | PASK | 2.46740460 |
| 6 | TSSK6 | 2.45597044 |
| 7 | GRK1 | 2.45351843 |
| 8 | EIF2AK3 | 2.43663580 |
| 9 | MST4 | 2.39036452 |
| 10 | MAP4K1 | 2.32468704 |
| 11 | MAP4K2 | 2.28642640 |
| 12 | ADRBK2 | 2.24497223 |
| 13 | PRKCI | 2.22066013 |
| 14 | VRK2 | 2.19512767 |
| 15 | FRK | 2.17395895 |
| 16 | NEK1 | 2.04160539 |
| 17 | CDK19 | 1.92390037 |
| 18 | TLK1 | 1.90687295 |
| 19 | ZAK | 1.88055347 |
| 20 | STK16 | 1.78223674 |
| 21 | WNK4 | 1.75123180 |
| 22 | TRIM28 | 1.69810646 |
| 23 | BMPR1B | 1.68815636 |
| 24 | EIF2AK1 | 1.57826162 |
| 25 | BUB1 | 1.56228665 |
| 26 | MAP3K12 | 1.54439241 |
| 27 | TAOK3 | 1.53774746 |
| 28 | BCKDK | 1.52563201 |
| 29 | MAPKAPK3 | 1.50727523 |
| 30 | TXK | 1.47942759 |
| 31 | OXSR1 | 1.46353747 |
| 32 | NME2 | 1.32455579 |
| 33 | INSRR | 1.32250238 |
| 34 | WNK3 | 1.31014594 |
| 35 | PINK1 | 1.28385925 |
| 36 | DAPK3 | 1.22139943 |
| 37 | DYRK2 | 1.21212886 |
| 38 | STK38L | 1.17249314 |
| 39 | TAF1 | 1.14961629 |
| 40 | PRKCG | 1.14282687 |
| 41 | PLK3 | 1.14198107 |
| 42 | NME1 | 1.08021046 |
| 43 | PRKCE | 1.02287186 |
| 44 | STK39 | 1.00739212 |
| 45 | TGFBR1 | 1.00327384 |
| 46 | PBK | 0.97693377 |
| 47 | TEC | 0.97036665 |
| 48 | ACVR1B | 0.95047893 |
| 49 | ADRBK1 | 0.88470518 |
| 50 | PLK2 | 0.85189802 |
| 51 | IKBKB | 0.81341927 |
| 52 | PIK3CG | 0.76648800 |
| 53 | VRK1 | 0.75438928 |
| 54 | DAPK1 | 0.72731113 |
| 55 | TNIK | 0.72417783 |
| 56 | GRK5 | 0.68424044 |
| 57 | FES | 0.67854371 |
| 58 | PAK3 | 0.67639715 |
| 59 | KIT | 0.67576650 |
| 60 | PDK2 | 0.66247889 |
| 61 | FLT3 | 0.65990649 |
| 62 | EIF2AK2 | 0.62689956 |
| 63 | CSNK1G1 | 0.60495656 |
| 64 | PLK4 | 0.58661021 |
| 65 | MAP2K6 | 0.56953395 |
| 66 | RPS6KA5 | 0.56300882 |
| 67 | PRKCD | 0.53194680 |
| 68 | TGFBR2 | 0.53045636 |
| 69 | PTK2B | 0.51940127 |
| 70 | CSNK1G2 | 0.50339386 |
| 71 | MYLK | 0.49456000 |
| 72 | SRPK1 | 0.48774181 |
| 73 | SIK3 | 0.47777747 |
| 74 | PRKCQ | 0.47608922 |
| 75 | NLK | 0.47350916 |
| 76 | MAPKAPK5 | 0.44700575 |
| 77 | CSNK2A1 | 0.44176716 |
| 78 | MKNK1 | 0.43452537 |
| 79 | CSNK1G3 | 0.42585371 |
| 80 | PLK1 | 0.42520490 |
| 81 | PRKCZ | 0.42313337 |
| 82 | ITK | 0.39683484 |
| 83 | CSNK2A2 | 0.39496386 |
| 84 | CDK8 | 0.38277365 |
| 85 | LCK | 0.35255707 |
| 86 | KDR | 0.34917319 |
| 87 | WNK1 | 0.34764689 |
| 88 | GRK7 | 0.34041691 |
| 89 | STK3 | 0.33971505 |
| 90 | MARK3 | 0.33885910 |
| 91 | CSNK1A1L | 0.33459300 |
| 92 | PDPK1 | 0.33225883 |
| 93 | PHKG2 | 0.31548590 |
| 94 | PHKG1 | 0.31548590 |
| 95 | ATR | 0.30895301 |
| 96 | PRKCB | 0.30388988 |
| 97 | AURKB | 0.30238235 |
| 98 | CSK | 0.30044954 |
| 99 | CSNK1A1 | 0.28539010 |
| 100 | ERBB3 | 0.26744968 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.80851857 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.78409140 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.38426300 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.09712766 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.90097682 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.82171111 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.76414770 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.65558263 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.61096754 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.41967568 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.31704782 |
| 12 | Parkinsons disease_Homo sapiens_hsa05012 | 2.31611130 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.21851004 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 2.10639169 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.99568499 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.96053778 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.81551439 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.81122667 |
| 19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.66842495 |
| 20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.56824489 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.51549744 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.46392298 |
| 23 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.39948504 |
| 24 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.33713269 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.32507091 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.29500361 |
| 27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.27953614 |
| 28 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.26345938 |
| 29 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.24486227 |
| 30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.22207713 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.21680042 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19904378 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.19103504 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.18860209 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.11596197 |
| 36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.09842319 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.06499336 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.03496197 |
| 39 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.01594621 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 0.98629849 |
| 41 | Mismatch repair_Homo sapiens_hsa03430 | 0.96644818 |
| 42 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.95167785 |
| 43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92588192 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.91056793 |
| 45 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.90689744 |
| 46 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.88501813 |
| 47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.86765569 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85217802 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84572021 |
| 50 | DNA replication_Homo sapiens_hsa03030 | 0.84420084 |
| 51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.84117571 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.83219202 |
| 53 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83131393 |
| 54 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.82532243 |
| 55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80658419 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80103386 |
| 57 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.79432683 |
| 58 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.77317465 |
| 59 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73367160 |
| 60 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.73085120 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69463334 |
| 62 | Viral myocarditis_Homo sapiens_hsa05416 | 0.66033949 |
| 63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65374097 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.65054837 |
| 65 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.64830999 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.64820454 |
| 67 | Base excision repair_Homo sapiens_hsa03410 | 0.63707657 |
| 68 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.61511369 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.60875887 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59431852 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56717119 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54239009 |
| 73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.54018401 |
| 74 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.51032847 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.47319742 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.46331397 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45786623 |
| 78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45682449 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.45604462 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45484762 |
| 81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.42993585 |
| 82 | Mineral absorption_Homo sapiens_hsa04978 | 0.42594964 |
| 83 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.42223856 |
| 84 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41505828 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41321074 |
| 86 | Spliceosome_Homo sapiens_hsa03040 | 0.40525771 |
| 87 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39467903 |
| 88 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.38032740 |
| 89 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37819005 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.33252564 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.33152605 |
| 92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31962268 |
| 93 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.31460511 |
| 94 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30999833 |
| 95 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30140606 |
| 96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.30019500 |
| 97 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.28703861 |
| 98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.28148149 |
| 99 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.28022473 |
| 100 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.26468226 |

