EEF1G

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.61745055
2viral transcription (GO:0019083)5.24337245
3translational termination (GO:0006415)5.14545632
4DNA unwinding involved in DNA replication (GO:0006268)5.11219726
5maturation of SSU-rRNA (GO:0030490)5.00890043
6formation of translation preinitiation complex (GO:0001731)4.82658367
7* translational elongation (GO:0006414)4.64299534
8DNA strand elongation involved in DNA replication (GO:0006271)4.60139020
9translational initiation (GO:0006413)4.46843155
10DNA replication initiation (GO:0006270)4.44343718
11nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.39255446
12ribosomal small subunit biogenesis (GO:0042274)4.37106533
13DNA strand elongation (GO:0022616)4.36046050
14IMP biosynthetic process (GO:0006188)4.33594198
15ribosomal large subunit biogenesis (GO:0042273)4.29319194
16folic acid-containing compound biosynthetic process (GO:0009396)4.29023417
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.28792858
18nucleobase biosynthetic process (GO:0046112)4.23072392
19protein targeting to ER (GO:0045047)4.16755455
20cotranslational protein targeting to membrane (GO:0006613)4.16013646
21telomere maintenance via semi-conservative replication (GO:0032201)4.09032503
22cellular protein complex disassembly (GO:0043624)4.06367058
23protein localization to kinetochore (GO:0034501)4.03357491
24viral life cycle (GO:0019058)4.00794817
25nuclear pore organization (GO:0006999)3.97799133
26establishment of protein localization to endoplasmic reticulum (GO:0072599)3.96697277
27mitotic nuclear envelope disassembly (GO:0007077)3.96481812
28COPI coating of Golgi vesicle (GO:0048205)3.90434857
29Golgi transport vesicle coating (GO:0048200)3.90434857
30protein localization to endoplasmic reticulum (GO:0070972)3.86581516
31proline biosynthetic process (GO:0006561)3.86073857
32IMP metabolic process (GO:0046040)3.85057710
33ribonucleoprotein complex biogenesis (GO:0022613)3.83795871
34spliceosomal tri-snRNP complex assembly (GO:0000244)3.77151073
35purine nucleobase biosynthetic process (GO:0009113)3.76479885
36DNA topological change (GO:0006265)3.74044563
37protein complex disassembly (GO:0043241)3.73952753
38nuclear pore complex assembly (GO:0051292)3.72225640
39nuclear envelope disassembly (GO:0051081)3.68803481
40membrane disassembly (GO:0030397)3.68803481
41DNA replication-dependent nucleosome assembly (GO:0006335)3.66757347
42DNA replication-dependent nucleosome organization (GO:0034723)3.66757347
43ribosome assembly (GO:0042255)3.62154552
44telomere maintenance via recombination (GO:0000722)3.60740701
45ribosome biogenesis (GO:0042254)3.54695785
46nucleosome disassembly (GO:0006337)3.53228842
47protein-DNA complex disassembly (GO:0032986)3.53228842
48DNA replication checkpoint (GO:0000076)3.53218162
49mitotic metaphase plate congression (GO:0007080)3.52744863
50macromolecular complex disassembly (GO:0032984)3.51725354
51mitotic recombination (GO:0006312)3.50819221
52telomere maintenance via telomere lengthening (GO:0010833)3.43008842
53nuclear-transcribed mRNA catabolic process (GO:0000956)3.40636520
54protein localization to chromosome, centromeric region (GO:0071459)3.37948208
55DNA duplex unwinding (GO:0032508)3.35750458
56DNA geometric change (GO:0032392)3.33615247
57regulation of RNA export from nucleus (GO:0046831)3.31759870
58rRNA processing (GO:0006364)3.30247295
59mRNA catabolic process (GO:0006402)3.22489314
60nucleotide-excision repair, DNA gap filling (GO:0006297)3.21279949
61regulation of spindle organization (GO:0090224)3.20702497
62RNA catabolic process (GO:0006401)3.19488811
63rRNA metabolic process (GO:0016072)3.19453068
64peptidyl-arginine methylation (GO:0018216)3.18447408
65peptidyl-arginine N-methylation (GO:0035246)3.18447408
66chromatin remodeling at centromere (GO:0031055)3.16262042
67regulation of translational fidelity (GO:0006450)3.16020028
68regulation of posttranscriptional gene silencing (GO:0060147)3.15828666
69regulation of gene silencing by miRNA (GO:0060964)3.15828666
70regulation of gene silencing by RNA (GO:0060966)3.15828666
71* translation (GO:0006412)3.14533195
72metaphase plate congression (GO:0051310)3.13411568
73dosage compensation (GO:0007549)3.13155570
74spliceosomal snRNP assembly (GO:0000387)3.13126137
75mRNA stabilization (GO:0048255)3.12103282
76RNA stabilization (GO:0043489)3.12103282
77negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.12061174
78CENP-A containing nucleosome assembly (GO:0034080)3.11515322
79negative regulation of RNA splicing (GO:0033119)3.07447509
80regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.05686644
813-UTR-mediated mRNA stabilization (GO:0070935)3.04436775
82somatic hypermutation of immunoglobulin genes (GO:0016446)3.03732965
83somatic diversification of immune receptors via somatic mutation (GO:0002566)3.03732965
84heterochromatin organization (GO:0070828)3.03127525
85ncRNA 3-end processing (GO:0043628)3.02807404
86DNA replication-independent nucleosome organization (GO:0034724)3.01335186
87DNA replication-independent nucleosome assembly (GO:0006336)3.01335186
88mitotic chromosome condensation (GO:0007076)3.00281093
89histone arginine methylation (GO:0034969)2.99423251
90peptidyl-arginine omega-N-methylation (GO:0035247)2.98637387
91regulation of translational initiation (GO:0006446)2.93594146
92mitotic sister chromatid cohesion (GO:0007064)2.93162916
93DNA deamination (GO:0045006)2.92641588
94mitotic sister chromatid segregation (GO:0000070)2.91994642
95regulation of mammary gland epithelial cell proliferation (GO:0033599)2.90068315
96regulation of sister chromatid cohesion (GO:0007063)2.88059479
97kinetochore organization (GO:0051383)2.87742565
98negative regulation of DNA repair (GO:0045738)2.87174463
99regulation of mitotic spindle organization (GO:0060236)2.85641448
100mRNA splicing, via spliceosome (GO:0000398)2.85108697
101RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.85108697
102RNA splicing, via transesterification reactions (GO:0000375)2.84980884
103pore complex assembly (GO:0046931)2.84456505
104establishment of integrated proviral latency (GO:0075713)2.84112395
105nuclear envelope organization (GO:0006998)2.83973364
106regulation of histone H3-K9 methylation (GO:0051570)2.82263964
107establishment of chromosome localization (GO:0051303)2.81591766
108pentose-phosphate shunt (GO:0006098)2.81523055
109regulation of translational termination (GO:0006449)2.81088458
110sister chromatid segregation (GO:0000819)2.80740118
111regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.80735264
112establishment of viral latency (GO:0019043)2.79577174
113pseudouridine synthesis (GO:0001522)2.78245895
114negative regulation of mRNA processing (GO:0050686)2.78084570
115negative regulation of mRNA metabolic process (GO:1903312)2.76311732
116ribonucleoprotein complex assembly (GO:0022618)2.75571947
117chromatin assembly or disassembly (GO:0006333)2.73961237
118tRNA aminoacylation for protein translation (GO:0006418)2.73666864
119DNA conformation change (GO:0071103)2.72580563
120protein targeting to membrane (GO:0006612)2.72018682
121rRNA transcription (GO:0009303)2.71821033
122regulation of nucleobase-containing compound transport (GO:0032239)2.71669147
123establishment of protein localization to membrane (GO:0090150)2.70808161
124translesion synthesis (GO:0019985)2.70228350
125regulation of helicase activity (GO:0051095)2.69423704
126postreplication repair (GO:0006301)2.69107034
127spliceosomal complex assembly (GO:0000245)2.68296866
128negative regulation of histone methylation (GO:0031061)2.68185100
129telomere maintenance (GO:0000723)2.67927815
130protein export from nucleus (GO:0006611)2.66675790
131DNA synthesis involved in DNA repair (GO:0000731)2.65878810
132chromosome condensation (GO:0030261)2.65377607
133poly(A)+ mRNA export from nucleus (GO:0016973)2.64451523
134DNA ligation (GO:0006266)2.63153823
135base-excision repair (GO:0006284)2.62623691
136double-strand break repair via nonhomologous end joining (GO:0006303)2.62205735
137non-recombinational repair (GO:0000726)2.62205735
138ribonucleoprotein complex subunit organization (GO:0071826)2.61744014
139retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.59262359
140tRNA aminoacylation (GO:0043039)2.57919397
141amino acid activation (GO:0043038)2.57919397
142RNA export from nucleus (GO:0006405)2.54079534
143cellular component biogenesis (GO:0044085)2.52593075
144negative regulation of erythrocyte differentiation (GO:0045647)2.52536737

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.50686898
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.52002609
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.91612215
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.69679244
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.34307415
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.29236441
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.84850453
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83745791
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.75338065
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.57053771
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.53850780
12EGR1_19374776_ChIP-ChIP_THP-1_Human2.46087173
13XRN2_22483619_ChIP-Seq_HELA_Human2.45173628
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35928310
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.35279876
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.33319769
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.28358553
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.27784701
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.25460454
20MYC_22102868_ChIP-Seq_BL_Human2.08961078
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05075426
22AR_21909140_ChIP-Seq_LNCAP_Human2.01388057
23ZNF263_19887448_ChIP-Seq_K562_Human1.97932569
24VDR_23849224_ChIP-Seq_CD4+_Human1.96594815
25E2F1_21310950_ChIP-Seq_MCF-7_Human1.91067133
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.90296213
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.86282585
28* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.85286871
29* TTF2_22483619_ChIP-Seq_HELA_Human1.84233135
30DCP1A_22483619_ChIP-Seq_HELA_Human1.82991968
31FOXP3_21729870_ChIP-Seq_TREG_Human1.80284128
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79444068
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.76754634
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74527808
35GABP_19822575_ChIP-Seq_HepG2_Human1.71508001
36* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.69327861
37CIITA_25753668_ChIP-Seq_RAJI_Human1.68647268
38TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.68536575
39NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.68375293
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.66775874
41SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.65713675
42ZFX_18555785_ChIP-Seq_MESCs_Mouse1.65516507
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60566900
44* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60099870
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56441294
46POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.56173475
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47830522
48SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.47225722
49ELK1_19687146_ChIP-ChIP_HELA_Human1.46801280
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45606252
51KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.42692557
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.42095243
53CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42077461
54KDM5A_27292631_Chip-Seq_BREAST_Human1.41380045
55HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34355842
56PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.30200901
57ELK3_25401928_ChIP-Seq_HUVEC_Human1.29594791
58KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29522024
59YY1_21170310_ChIP-Seq_MESCs_Mouse1.28503291
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28152096
61RBPJ_22232070_ChIP-Seq_NCS_Mouse1.27753965
62* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26445627
63* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.25810831
64VDR_21846776_ChIP-Seq_THP-1_Human1.25413022
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25111326
66TFEB_21752829_ChIP-Seq_HELA_Human1.23972538
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.23558514
68TCF7_22412390_ChIP-Seq_EML_Mouse1.23000983
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22854771
70* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22685011
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.20728161
72ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.19799191
73KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16603482
74RACK7_27058665_Chip-Seq_MCF-7_Human1.16540037
75TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15473488
76* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15245853
77NCOR1_26117541_ChIP-Seq_K562_Human1.13700447
78TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13654878
79TP63_19390658_ChIP-ChIP_HaCaT_Human1.12213085
80TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09823483
81CHD1_26751641_Chip-Seq_LNCaP_Human1.09179838
82* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.07819120
83* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.07719779
84* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06845961
85* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.06127767
86LXR_22292898_ChIP-Seq_THP-1_Human1.05564010
87ESR1_15608294_ChIP-ChIP_MCF-7_Human1.04577204
88ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04552594
89NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.03242308
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02544034
91KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01937163
92* MAF_26560356_Chip-Seq_TH1_Human1.01359119
93KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00413151
94TET1_21451524_ChIP-Seq_MESCs_Mouse0.98764136
95CLOCK_20551151_ChIP-Seq_293T_Human0.98761114
96* KDM2B_26808549_Chip-Seq_DND41_Human0.97803825
97UTX_26944678_Chip-Seq_JUKART_Human0.97149269
98* SRF_21415370_ChIP-Seq_HL-1_Mouse0.94954817
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.94754268
100NANOG_21062744_ChIP-ChIP_HESCs_Human0.94149966
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93840589
102MAF_26560356_Chip-Seq_TH2_Human0.93644568
103* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93225994
104NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92717556
105TP63_17297297_ChIP-ChIP_HaCaT_Human0.92051807
106OCT4_18692474_ChIP-Seq_MEFs_Mouse0.92032808
107CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91247508
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90239938
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89000109
110HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88296845
111KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.88044455
112KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.88044455
113KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.88044455
114NOTCH1_21737748_ChIP-Seq_TLL_Human0.87040337
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86127052
116* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85029000
117E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.84619057
118MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.84355982
119ELK1_22589737_ChIP-Seq_MCF10A_Human0.84155264
120MYC_18940864_ChIP-ChIP_HL60_Human0.83342912
121NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.83183524

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.66397898
2MP0004957_abnormal_blastocyst_morpholog4.23439092
3MP0010094_abnormal_chromosome_stability3.96313814
4MP0003111_abnormal_nucleus_morphology3.87567479
5MP0003077_abnormal_cell_cycle3.59052799
6MP0008057_abnormal_DNA_replication3.02395870
7MP0010352_gastrointestinal_tract_polyps2.98264462
8MP0008058_abnormal_DNA_repair2.73503657
9MP0008007_abnormal_cellular_replicative2.68725459
10MP0003123_paternal_imprinting2.60345783
11MP0001730_embryonic_growth_arrest2.44258003
12MP0002396_abnormal_hematopoietic_system2.41941979
13MP0008932_abnormal_embryonic_tissue2.39614497
14MP0002009_preneoplasia2.26568872
15MP0000350_abnormal_cell_proliferation2.23894670
16MP0010307_abnormal_tumor_latency1.83590172
17MP0001697_abnormal_embryo_size1.81395371
18MP0001672_abnormal_embryogenesis/_devel1.79003909
19MP0005380_embryogenesis_phenotype1.79003909
20MP0010030_abnormal_orbit_morphology1.78215170
21MP0000490_abnormal_crypts_of1.77364478
22MP0004808_abnormal_hematopoietic_stem1.76334271
23MP0000566_synostosis1.75112323
24MP0003705_abnormal_hypodermis_morpholog1.73934036
25MP0000537_abnormal_urethra_morphology1.73119999
26MP0004197_abnormal_fetal_growth/weight/1.72968417
27MP0002080_prenatal_lethality1.69405895
28MP0002084_abnormal_developmental_patter1.66056027
29MP0003984_embryonic_growth_retardation1.65601876
30MP0002085_abnormal_embryonic_tissue1.64212819
31MP0002088_abnormal_embryonic_growth/wei1.62510841
32MP0004185_abnormal_adipocyte_glucose1.61885598
33MP0001346_abnormal_lacrimal_gland1.61851127
34MP0003567_abnormal_fetal_cardiomyocyte1.60890329
35MP0002086_abnormal_extraembryonic_tissu1.55544423
36MP0003786_premature_aging1.54437609
37MP0006054_spinal_hemorrhage1.53117160
38MP0005076_abnormal_cell_differentiation1.49296376
39MP0009053_abnormal_anal_canal1.42265436
40MP0005451_abnormal_body_composition1.36619784
41MP0000313_abnormal_cell_death1.36343639
42MP0002019_abnormal_tumor_incidence1.36235846
43MP0002796_impaired_skin_barrier1.35839760
44MP0003121_genomic_imprinting1.31180649
45MP0001293_anophthalmia1.27711772
46MP0003566_abnormal_cell_adhesion1.27206721
47MP0003806_abnormal_nucleotide_metabolis1.23561294
48MP0009333_abnormal_splenocyte_physiolog1.23428319
49MP0002249_abnormal_larynx_morphology1.21837774
50MP0004858_abnormal_nervous_system1.21322924
51MP0003119_abnormal_digestive_system1.18923933
52MP0005023_abnormal_wound_healing1.17822785
53MP0008877_abnormal_DNA_methylation1.15844457
54MP0001545_abnormal_hematopoietic_system1.15495999
55MP0005397_hematopoietic_system_phenotyp1.15495999
56MP0003763_abnormal_thymus_physiology1.09590883
57MP0000678_abnormal_parathyroid_gland1.07601906
58MP0008995_early_reproductive_senescence1.07036720
59MP0000703_abnormal_thymus_morphology1.06211913
60MP0008260_abnormal_autophagy1.04765906
61MP0003941_abnormal_skin_development1.03653847
62MP0003385_abnormal_body_wall1.02905314
63MP0004133_heterotaxia1.02300970
64MP0002098_abnormal_vibrissa_morphology1.00883390
65MP0002111_abnormal_tail_morphology0.99621508
66MP0000377_abnormal_hair_follicle0.97932416
67MP0003943_abnormal_hepatobiliary_system0.97287865
68MP0004782_abnormal_surfactant_physiolog0.96995046
69MP0001661_extended_life_span0.96531100
70MP0001849_ear_inflammation0.95072411
71MP0000858_altered_metastatic_potential0.94676208
72MP0003315_abnormal_perineum_morphology0.94315229
73MP0009672_abnormal_birth_weight0.93115062
74MP0002398_abnormal_bone_marrow0.91982299
75MP0001873_stomach_inflammation0.91877204
76MP0000428_abnormal_craniofacial_morphol0.91332599
77MP0000358_abnormal_cell_content/0.91219611
78MP0000733_abnormal_muscle_development0.90253793
79MP0003890_abnormal_embryonic-extraembry0.90009731
80MP0010630_abnormal_cardiac_muscle0.89634068
81MP0001915_intracranial_hemorrhage0.89389149
82MP0002722_abnormal_immune_system0.89237009
83MP0009278_abnormal_bone_marrow0.87542145
84MP0005075_abnormal_melanosome_morpholog0.86948659
85MP0009379_abnormal_foot_pigmentation0.82701140
86MP0000477_abnormal_intestine_morphology0.81944340
87MP0002210_abnormal_sex_determination0.81334726
88MP0000689_abnormal_spleen_morphology0.80872964
89MP0010234_abnormal_vibrissa_follicle0.79228176
90MP0000681_abnormal_thyroid_gland0.78793407
91MP0009697_abnormal_copulation0.78772845
92MP0005501_abnormal_skin_physiology0.78509916
93MP0002166_altered_tumor_susceptibility0.78448582
94MP0005384_cellular_phenotype0.77372398
95MP0004233_abnormal_muscle_weight0.77173038
96MP0005666_abnormal_adipose_tissue0.77050427
97MP0003718_maternal_effect0.76791390
98MP0001145_abnormal_male_reproductive0.76592695
99MP0002114_abnormal_axial_skeleton0.75828312
100MP0009703_decreased_birth_body0.75373815
101MP0006035_abnormal_mitochondrial_morpho0.75372619
102MP0002653_abnormal_ependyma_morphology0.74784753
103MP0006292_abnormal_olfactory_placode0.74724091
104MP0003937_abnormal_limbs/digits/tail_de0.73720569
105MP0001727_abnormal_embryo_implantation0.73656692
106MP0005621_abnormal_cell_physiology0.73127105
107MP0000750_abnormal_muscle_regeneration0.72884147
108MP0000462_abnormal_digestive_system0.72187336
109MP0001340_abnormal_eyelid_morphology0.71994928
110MP0002092_abnormal_eye_morphology0.71941205
111MP0002429_abnormal_blood_cell0.71335045
112MP0003115_abnormal_respiratory_system0.71314868
113MP0003861_abnormal_nervous_system0.71255695
114MP0003283_abnormal_digestive_organ0.69055456
115MP0009931_abnormal_skin_appearance0.68301921
116MP0002697_abnormal_eye_size0.68145020
117MP0008438_abnormal_cutaneous_collagen0.67365438
118MP0002925_abnormal_cardiovascular_devel0.66606609
119MP0003221_abnormal_cardiomyocyte_apopto0.66034289
120MP0001286_abnormal_eye_development0.64626577
121MP0003942_abnormal_urinary_system0.63608501
122MP0008770_decreased_survivor_rate0.62658148
123MP0000516_abnormal_urinary_system0.62163735
124MP0005367_renal/urinary_system_phenotyp0.62163735
125MP0002877_abnormal_melanocyte_morpholog0.61250611
126MP0002160_abnormal_reproductive_system0.61123327
127MP0000432_abnormal_head_morphology0.60900479
128MP0002932_abnormal_joint_morphology0.59533692
129MP0004264_abnormal_extraembryonic_tissu0.58404975
130MP0000653_abnormal_sex_gland0.58201793
131MP0003935_abnormal_craniofacial_develop0.57967168
132MP0002938_white_spotting0.56748934

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.81380922
2Abnormality of cells of the erythroid lineage (HP:0012130)4.67781206
3Abnormal number of erythroid precursors (HP:0012131)4.24215091
4Colon cancer (HP:0003003)4.07217659
5Birth length less than 3rd percentile (HP:0003561)3.84467128
6Selective tooth agenesis (HP:0001592)3.69030842
7Ependymoma (HP:0002888)3.68749137
8Microvesicular hepatic steatosis (HP:0001414)3.26671202
9Medulloblastoma (HP:0002885)3.17181865
10Oral leukoplakia (HP:0002745)3.16164375
11Macrocytic anemia (HP:0001972)3.11399341
12Abnormality of the anterior horn cell (HP:0006802)3.07561981
13Degeneration of anterior horn cells (HP:0002398)3.07561981
14Breast hypoplasia (HP:0003187)3.02860320
15Pallor (HP:0000980)3.00457265
16High anterior hairline (HP:0009890)2.91777494
17Aplastic anemia (HP:0001915)2.87863008
18Thrombocytosis (HP:0001894)2.82187159
19Trismus (HP:0000211)2.79874123
20Broad distal phalanx of finger (HP:0009836)2.72782598
2111 pairs of ribs (HP:0000878)2.70467562
22Progressive muscle weakness (HP:0003323)2.66366270
23Missing ribs (HP:0000921)2.65111989
24Patellar aplasia (HP:0006443)2.62338613
25Basal cell carcinoma (HP:0002671)2.62075695
26Agnosia (HP:0010524)2.61737018
27Absent thumb (HP:0009777)2.57517987
28Deviation of the thumb (HP:0009603)2.54673564
29Neoplasm of the pancreas (HP:0002894)2.54044503
30Rhabdomyosarcoma (HP:0002859)2.52826091
31Proximal placement of thumb (HP:0009623)2.52546421
32Carpal bone hypoplasia (HP:0001498)2.48033324
33Aplasia/Hypoplasia of the patella (HP:0006498)2.47900516
34Rough bone trabeculation (HP:0100670)2.44627974
35Multiple enchondromatosis (HP:0005701)2.44356654
36Asymmetry of the thorax (HP:0001555)2.40630252
37Cholecystitis (HP:0001082)2.39495884
38Abnormal gallbladder physiology (HP:0012438)2.39495884
39Insomnia (HP:0100785)2.36050480
40Atresia of the external auditory canal (HP:0000413)2.35178254
41Abnormality of the calcaneus (HP:0008364)2.34135029
42Astrocytoma (HP:0009592)2.33900092
43Abnormality of the astrocytes (HP:0100707)2.33900092
44Abnormal number of incisors (HP:0011064)2.32930026
45Progressive external ophthalmoplegia (HP:0000590)2.31808827
46Ankyloglossia (HP:0010296)2.30978000
47Increased nuchal translucency (HP:0010880)2.28387927
48Deep palmar crease (HP:0006191)2.27337832
49Chromsome breakage (HP:0040012)2.26910235
50Myelodysplasia (HP:0002863)2.26797143
51Microretrognathia (HP:0000308)2.21241748
52Flat acetabular roof (HP:0003180)2.20125615
53Protrusio acetabuli (HP:0003179)2.18221053
54Amaurosis fugax (HP:0100576)2.16185364
55Angiofibromas (HP:0010615)2.14480200
56Adenoma sebaceum (HP:0009720)2.14480200
57Acute lymphatic leukemia (HP:0006721)2.13610019
58Glossoptosis (HP:0000162)2.13154748
59Meckel diverticulum (HP:0002245)2.11164043
60Metaphyseal cupping (HP:0003021)2.10701228
61Abnormality of the labia minora (HP:0012880)2.09434345
62Biliary tract neoplasm (HP:0100574)2.08889258
63Abnormality of chromosome stability (HP:0003220)2.07372632
64Short 4th metacarpal (HP:0010044)2.06924441
65Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.06924441
66Slender long bone (HP:0003100)2.05752656
67Ragged-red muscle fibers (HP:0003200)2.04398696
68Premature skin wrinkling (HP:0100678)2.04337438
69Abnormality of the preputium (HP:0100587)2.03674185
70Elfin facies (HP:0004428)2.03660696
71Abnormality of oral frenula (HP:0000190)2.01131559
72Overriding aorta (HP:0002623)2.00954791
73Disproportionate tall stature (HP:0001519)2.00724334
74Long palpebral fissure (HP:0000637)2.00700328
75Premature graying of hair (HP:0002216)1.99499188
76Reticulocytosis (HP:0001923)1.98913804
77Glioma (HP:0009733)1.98849780
78Pointed chin (HP:0000307)1.98772990
79Abnormality of the ileum (HP:0001549)1.98690994
80Abnormality of reticulocytes (HP:0004312)1.98532177
81Aplasia/Hypoplasia of the sacrum (HP:0008517)1.98005084
82Neoplasm of the colon (HP:0100273)1.97034556
83Absent radius (HP:0003974)1.96637986
84Neoplasm of striated muscle (HP:0009728)1.95882877
85Microglossia (HP:0000171)1.93014482
86Deep philtrum (HP:0002002)1.91862024
87Neoplasm of the oral cavity (HP:0100649)1.91761976
88Ankle contracture (HP:0006466)1.91637201
89Tracheoesophageal fistula (HP:0002575)1.89702029
90Breech presentation (HP:0001623)1.88082039
91Cerebral hypomyelination (HP:0006808)1.87934898
92Squamous cell carcinoma (HP:0002860)1.87777093
93Chromosomal breakage induced by crosslinking agents (HP:0003221)1.86901634
94Truncus arteriosus (HP:0001660)1.86845622
95Duodenal stenosis (HP:0100867)1.86616996
96Small intestinal stenosis (HP:0012848)1.86616996
97Trigonocephaly (HP:0000243)1.86426373
98Increased density of long bones (HP:0006392)1.86313652
99Centrally nucleated skeletal muscle fibers (HP:0003687)1.86204026
100Seborrheic dermatitis (HP:0001051)1.85914811
101High pitched voice (HP:0001620)1.85487571
102Thin ribs (HP:0000883)1.83134365
103Duplication of thumb phalanx (HP:0009942)1.81888953
104Calcaneovalgus deformity (HP:0001848)1.80691418
105Aplasia/Hypoplasia of the uvula (HP:0010293)1.80515276
106Renal duplication (HP:0000075)1.80198781
107Asplenia (HP:0001746)1.80174360
108Ovarian neoplasm (HP:0100615)1.79509343
109Absent forearm bone (HP:0003953)1.79416922
110Aplasia involving forearm bones (HP:0009822)1.79416922
111Cortical dysplasia (HP:0002539)1.77514145
112Abnormality of the thoracic spine (HP:0100711)1.76987360
113Patellar dislocation (HP:0002999)1.76641475
114Colitis (HP:0002583)1.75354686
115Neoplasm of the rectum (HP:0100743)1.75258794
116Horseshoe kidney (HP:0000085)1.75022590
117Abnormality of the distal phalanx of the thumb (HP:0009617)1.74455611
118Broad palm (HP:0001169)1.74431402
119Abnormality of the fingertips (HP:0001211)1.72734572
120Atrophy/Degeneration involving motor neurons (HP:0007373)1.72104048
121Cellular immunodeficiency (HP:0005374)1.71583373
122Preauricular skin tag (HP:0000384)1.71040227
123Abnormal lung lobation (HP:0002101)1.70743480
124Pelvic girdle muscle weakness (HP:0003749)1.70472016
125Abnormality of abdominal situs (HP:0011620)1.70424302
126Abdominal situs inversus (HP:0003363)1.70424302
127Stenosis of the external auditory canal (HP:0000402)1.69899393
128Overlapping toe (HP:0001845)1.69395495
129Flattened epiphyses (HP:0003071)1.69392121
130Aplasia/Hypoplasia of the spleen (HP:0010451)1.68993447
131Syringomyelia (HP:0003396)1.68787877
132Spinal cord lesions (HP:0100561)1.68787877
133Septate vagina (HP:0001153)1.68713143
134Hyperacusis (HP:0010780)1.67821597
135Intestinal polyp (HP:0005266)1.67782657
136Bone marrow hypocellularity (HP:0005528)1.67714692
137Aplasia/hypoplasia of the humerus (HP:0006507)1.67689022
138Sloping forehead (HP:0000340)1.67644601
139Heterotopia (HP:0002282)1.67409454
140Hypoplasia of the pons (HP:0012110)1.66893174
141Nephroblastoma (Wilms tumor) (HP:0002667)1.66804016
142Supernumerary spleens (HP:0009799)1.66489985
143Dysmetric saccades (HP:0000641)1.66190524
144Abnormal trabecular bone morphology (HP:0100671)1.65925703
145Abnormality of glycolysis (HP:0004366)1.65374548
146Skin tags (HP:0010609)1.65179079
147Aplasia/Hypoplasia of the sternum (HP:0006714)1.64660867
148Flared metaphyses (HP:0003015)1.64389099
149Germ cell neoplasia (HP:0100728)1.63282489
150Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.62214390
151Absent epiphyses (HP:0010577)1.62214390
152Thoracic kyphosis (HP:0002942)1.61377816
153Abnormality of cochlea (HP:0000375)1.60334833
154Myopathic facies (HP:0002058)1.60188020
155Viral hepatitis (HP:0006562)1.59814091
156Abnormality of small intestinal villus morphology (HP:0011472)1.59476750
157Villous atrophy (HP:0011473)1.59476750
158Premature ovarian failure (HP:0008209)1.58944459
159Cafe-au-lait spot (HP:0000957)1.58684178
160Bowel incontinence (HP:0002607)1.58460385
161Hypoparathyroidism (HP:0000829)1.57359967
162Coarctation of aorta (HP:0001680)1.56792108
163Anteriorly placed anus (HP:0001545)1.56474300
164Depressed nasal ridge (HP:0000457)1.54316243
165Thick lower lip vermilion (HP:0000179)1.52847695
166Facial hemangioma (HP:0000329)1.52801343
167Leiomyosarcoma (HP:0100243)1.51950545
168Uterine leiomyosarcoma (HP:0002891)1.51950545
169Acute myeloid leukemia (HP:0004808)1.51737470
170Abnormality of the phalanges of the hallux (HP:0010057)1.50583240
171Spina bifida occulta (HP:0003298)1.48773461
172Abnormal large intestine physiology (HP:0012700)1.48231785

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.95465236
2CDC73.77647756
3WEE13.66105746
4BUB13.65800342
5EEF2K2.96337214
6TSSK62.68735490
7NME22.65455548
8PASK2.60932935
9EIF2AK12.52931633
10NEK22.52288138
11ICK2.46710976
12PRPF4B2.36727891
13RPS6KB22.31835318
14PKN22.27897482
15NEK12.23839249
16CDK192.09560001
17TGFBR12.07452403
18VRK22.04511301
19TTK1.90910069
20SRPK11.86030681
21TLK11.84649485
22TESK21.75183668
23RPS6KA41.73459130
24MAP3K101.70818308
25SCYL21.70186668
26EPHA21.69007867
27MKNK11.67673319
28PBK1.65986223
29CDK121.64746944
30PLK11.62260240
31CDK71.60914085
32ACVR1B1.58199221
33ATR1.55643856
34BRSK21.54885685
35AURKB1.54196050
36PAK41.53121606
37FLT31.49884479
38MAP3K81.48045297
39LRRK21.45646332
40TRIB31.38904990
41CDK41.36916539
42EIF2AK31.36349531
43DYRK31.29504905
44STK101.28522674
45PLK31.22866041
46SIK11.19976437
47VRK11.17590277
48TAF11.13276558
49CHEK11.12183121
50ALK1.11856728
51IRAK31.10774714
52AURKA1.05302846
53FGFR41.05094714
54MAP4K11.04512418
55TESK11.04316777
56CHEK21.03306232
57PLK41.02156158
58MAP2K30.99091745
59KSR20.99056716
60CLK10.97159036
61MAP2K20.94638359
62MKNK20.94063917
63MAPKAPK30.86367281
64STK160.85333350
65PIM20.85116828
66BRSK10.84697178
67PIM10.84631115
68CDK60.83098460
69TTN0.83095954
70CDK20.79564380
71ILK0.79187765
72STK40.78575067
73ATM0.76690038
74PAK20.74257824
75CSNK2A20.71951270
76PAK10.70006187
77BRD40.67396013
78LATS10.66634977
79MTOR0.65301979
80ERN10.63774574
81KDR0.63418130
82ZAP700.60782643
83TYRO30.60488356
84MAP3K110.59799797
85RPS6KB10.59679486
86CDK90.58744835
87PRKD30.57776907
88CSNK2A10.55944771
89BTK0.55838698
90CCNB10.51644365
91FGFR10.50627534
92PRKCI0.50191304
93CDK10.49648242
94RAF10.49287444
95LATS20.48547384
96NME10.48240526
97PTK60.46892863
98TAOK20.46268754
99CDK80.46219265
100AKT20.46162259
101MAPK110.45358597
102BMX0.44698789
103ZAK0.44586216
104RPS6KA60.43230429
105MAP3K130.43210112
106DYRK1B0.41985131
107MAP3K30.41113925
108STK30.41014621
109NEK90.40754308
110RET0.40588202
111BCKDK0.39954180
112CDK11A0.39569506
113CSNK1E0.39349720
114MELK0.38683048
115EIF2AK20.37858631
116MST1R0.37050499
117MAP3K60.36348768
118RPS6KA50.34785495
119ARAF0.33894183
120PRKDC0.33025161
121JAK30.32810286
122KSR10.31902115
123PDK40.31331188
124PDK30.31331188
125LIMK10.29955386
126GRK60.28169282
127IRAK20.27423395
128RPS6KC10.25116661
129RPS6KL10.25116661
130RPS6KA10.24484332
131PDGFRA0.24101141
132CSF1R0.23606405
133BRAF0.23419108
134MST40.22497525

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.87386949
2Ribosome_Homo sapiens_hsa030104.22772362
3Mismatch repair_Homo sapiens_hsa034304.14359606
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.40081063
5Spliceosome_Homo sapiens_hsa030403.26968046
6RNA transport_Homo sapiens_hsa030133.16736791
7One carbon pool by folate_Homo sapiens_hsa006702.94802159
8Base excision repair_Homo sapiens_hsa034102.94136266
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.88184884
10Proteasome_Homo sapiens_hsa030502.84073556
11Nucleotide excision repair_Homo sapiens_hsa034202.75899957
12RNA polymerase_Homo sapiens_hsa030202.61702958
13Homologous recombination_Homo sapiens_hsa034402.56680249
14Cell cycle_Homo sapiens_hsa041102.53786620
15Pyrimidine metabolism_Homo sapiens_hsa002402.15700386
16Non-homologous end-joining_Homo sapiens_hsa034501.84457109
17mRNA surveillance pathway_Homo sapiens_hsa030151.75796213
18Fanconi anemia pathway_Homo sapiens_hsa034601.70237694
19RNA degradation_Homo sapiens_hsa030181.70009194
20p53 signaling pathway_Homo sapiens_hsa041151.57279964
21Basal transcription factors_Homo sapiens_hsa030221.44090369
22Epstein-Barr virus infection_Homo sapiens_hsa051691.19638194
23Antigen processing and presentation_Homo sapiens_hsa046121.14938988
24Viral carcinogenesis_Homo sapiens_hsa052031.09441005
25Systemic lupus erythematosus_Homo sapiens_hsa053221.08692550
26Cyanoamino acid metabolism_Homo sapiens_hsa004601.05464117
27Purine metabolism_Homo sapiens_hsa002301.04136710
28Biosynthesis of amino acids_Homo sapiens_hsa012300.99929347
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.99859116
30Thyroid cancer_Homo sapiens_hsa052160.93446829
31HTLV-I infection_Homo sapiens_hsa051660.92404719
32Herpes simplex infection_Homo sapiens_hsa051680.91596364
33Lysine degradation_Homo sapiens_hsa003100.90447315
34B cell receptor signaling pathway_Homo sapiens_hsa046620.88366396
35Selenocompound metabolism_Homo sapiens_hsa004500.86247913
36Small cell lung cancer_Homo sapiens_hsa052220.85689565
37Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84108697
38Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83739716
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82546728
40VEGF signaling pathway_Homo sapiens_hsa043700.80816584
41Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.80088085
42Other glycan degradation_Homo sapiens_hsa005110.79899911
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.79725181
44Oocyte meiosis_Homo sapiens_hsa041140.78937601
45Pentose phosphate pathway_Homo sapiens_hsa000300.78356196
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.76886910
47MicroRNAs in cancer_Homo sapiens_hsa052060.76601742
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.76058838
49ErbB signaling pathway_Homo sapiens_hsa040120.72554386
50Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.70550561
51Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70190530
52Insulin signaling pathway_Homo sapiens_hsa049100.69602695
53Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68780559
54Inositol phosphate metabolism_Homo sapiens_hsa005620.67065849
55Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.66868384
56Renal cell carcinoma_Homo sapiens_hsa052110.65747892
57Pyruvate metabolism_Homo sapiens_hsa006200.65571935
58Basal cell carcinoma_Homo sapiens_hsa052170.64811983
59Sulfur relay system_Homo sapiens_hsa041220.64680481
60Bladder cancer_Homo sapiens_hsa052190.64658913
61Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64144072
62Hippo signaling pathway_Homo sapiens_hsa043900.63882296
63Chronic myeloid leukemia_Homo sapiens_hsa052200.63233681
642-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.62948988
65Glioma_Homo sapiens_hsa052140.62477125
66Carbon metabolism_Homo sapiens_hsa012000.61039751
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60541925
68N-Glycan biosynthesis_Homo sapiens_hsa005100.59340314
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.59085076
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.58152809
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.56925370
72Folate biosynthesis_Homo sapiens_hsa007900.56601790
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55696256
74TGF-beta signaling pathway_Homo sapiens_hsa043500.54654870
75Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54619623
76AMPK signaling pathway_Homo sapiens_hsa041520.54602196
77Apoptosis_Homo sapiens_hsa042100.54570240
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54301732
79Colorectal cancer_Homo sapiens_hsa052100.53864136
80Drug metabolism - other enzymes_Homo sapiens_hsa009830.53483384
81Shigellosis_Homo sapiens_hsa051310.51836931
82* Legionellosis_Homo sapiens_hsa051340.51737590
83Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.51695241
84Choline metabolism in cancer_Homo sapiens_hsa052310.50431704
85HIF-1 signaling pathway_Homo sapiens_hsa040660.49364535
86Primary immunodeficiency_Homo sapiens_hsa053400.47032868
87Notch signaling pathway_Homo sapiens_hsa043300.46885454
88Prolactin signaling pathway_Homo sapiens_hsa049170.44972319
89Acute myeloid leukemia_Homo sapiens_hsa052210.43460468
90Adherens junction_Homo sapiens_hsa045200.43355783
91Protein export_Homo sapiens_hsa030600.43248712
92Viral myocarditis_Homo sapiens_hsa054160.43242495
93Galactose metabolism_Homo sapiens_hsa000520.43077866
94Hepatitis B_Homo sapiens_hsa051610.41920536
95Pathways in cancer_Homo sapiens_hsa052000.38661653
96Measles_Homo sapiens_hsa051620.37954254
97Proteoglycans in cancer_Homo sapiens_hsa052050.37781386
98Alcoholism_Homo sapiens_hsa050340.37579528
99mTOR signaling pathway_Homo sapiens_hsa041500.36259423
100T cell receptor signaling pathway_Homo sapiens_hsa046600.36163755
101Hedgehog signaling pathway_Homo sapiens_hsa043400.35995492
102Fatty acid elongation_Homo sapiens_hsa000620.35488208
103Glutathione metabolism_Homo sapiens_hsa004800.34482611
104Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.33746941
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33324213
106Fructose and mannose metabolism_Homo sapiens_hsa000510.31732777
107Hepatitis C_Homo sapiens_hsa051600.31466603
108Non-small cell lung cancer_Homo sapiens_hsa052230.29800328
109NF-kappa B signaling pathway_Homo sapiens_hsa040640.26051571
110Influenza A_Homo sapiens_hsa051640.25931096
111Leukocyte transendothelial migration_Homo sapiens_hsa046700.25686132
112Prostate cancer_Homo sapiens_hsa052150.25684406
113PI3K-Akt signaling pathway_Homo sapiens_hsa041510.24098932
114Tight junction_Homo sapiens_hsa045300.23335596
115Hematopoietic cell lineage_Homo sapiens_hsa046400.21535409
116Melanoma_Homo sapiens_hsa052180.21155696
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.20990381
118Focal adhesion_Homo sapiens_hsa045100.19700069
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.19308530
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.19228017
121ECM-receptor interaction_Homo sapiens_hsa045120.19093475
122Huntingtons disease_Homo sapiens_hsa050160.18855705
123Endometrial cancer_Homo sapiens_hsa052130.18471602
124Renin-angiotensin system_Homo sapiens_hsa046140.17793646
125Wnt signaling pathway_Homo sapiens_hsa043100.16308761
126Pancreatic cancer_Homo sapiens_hsa052120.15815677

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