EEF2KMT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1RNA localization (GO:0006403)9.97686589
2negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 8.95631364
3maturation of 5.8S rRNA (GO:0000460)8.59975255
4regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 7.76509305
5positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)7.65687148
6signal complex assembly (GO:0007172)7.54648729
7negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)7.52308488
8positive regulation of translational initiation (GO:0045948)7.35099471
9megakaryocyte development (GO:0035855)6.57946795
10ribosomal small subunit assembly (GO:0000028)6.40748074
11regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)6.33641482
12positive regulation of signal transduction by p53 class mediator (GO:1901798)6.16340524
13establishment of protein localization to mitochondrial membrane (GO:0090151)6.04756663
14DNA deamination (GO:0045006)5.77003601
15secretory granule organization (GO:0033363)5.13482172
16negative regulation of translational initiation (GO:0045947)4.82901464
17negative regulation of signal transduction by p53 class mediator (GO:1901797)4.67487304
18protein complex biogenesis (GO:0070271)4.53190713
19platelet formation (GO:0030220)4.52786116
20SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.40387253
21mitochondrial respiratory chain complex assembly (GO:0033108)4.37832298
22cotranslational protein targeting to membrane (GO:0006613)4.31262697
23pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.29637977
24viral transcription (GO:0019083)4.27856384
25protein targeting to ER (GO:0045047)4.27684806
26negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230)4.26032784
27inner mitochondrial membrane organization (GO:0007007)4.15210312
28translational termination (GO:0006415)4.11859246
29protein localization to endoplasmic reticulum (GO:0070972)4.06119057
30establishment of protein localization to endoplasmic reticulum (GO:0072599)4.03425586
31ribosomal large subunit biogenesis (GO:0042273)3.97523288
32regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516)3.96776432
33ribosomal small subunit biogenesis (GO:0042274)3.96411454
34regulation of translation in response to stress (GO:0043555)3.84023715
35chaperone-mediated protein transport (GO:0072321)3.72502375
36tRNA methylation (GO:0030488)3.72500519
37maturation of SSU-rRNA (GO:0030490)3.69777706
38regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229)3.69238316
39signal peptide processing (GO:0006465)3.66708760
40T cell apoptotic process (GO:0070231)3.63674946
41DNA replication-dependent nucleosome organization (GO:0034723)3.63376259
42DNA replication-dependent nucleosome assembly (GO:0006335)3.63376259
43translational elongation (GO:0006414)3.58834682
44regulation of oxidative phosphorylation (GO:0002082)3.57473891
45pyrimidine nucleotide catabolic process (GO:0006244)3.53177631
46regulation of translational initiation (GO:0006446)3.52676109
47daunorubicin metabolic process (GO:0044597)3.46306121
48polyketide metabolic process (GO:0030638)3.46306121
49doxorubicin metabolic process (GO:0044598)3.46306121
50proteasome assembly (GO:0043248)3.45779249
51cullin deneddylation (GO:0010388)3.42325838
52transcription elongation from RNA polymerase III promoter (GO:0006385)3.38566933
53termination of RNA polymerase III transcription (GO:0006386)3.38566933
54response to interferon-beta (GO:0035456)3.37087169
55fusion of sperm to egg plasma membrane (GO:0007342)3.35277378
56ribosome assembly (GO:0042255)3.34454173
57negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.34333277
58telomere maintenance via semi-conservative replication (GO:0032201)3.32036999
59deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.29640931
60establishment of protein localization to mitochondrion (GO:0072655)3.28227855
61positive regulation of macrophage differentiation (GO:0045651)3.26344850
62regulation of double-strand break repair via homologous recombination (GO:0010569)3.25306695
63DNA replication checkpoint (GO:0000076)3.25081058
64rRNA modification (GO:0000154)3.24892095
65viral life cycle (GO:0019058)3.23867449
66protein deneddylation (GO:0000338)3.16847223
67translation (GO:0006412)3.16174320
68nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.14544407
69peptidyl-histidine modification (GO:0018202)3.12829239
70pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.11520156
71regulation of mitochondrial translation (GO:0070129)3.11046467
72ribonucleoprotein complex biogenesis (GO:0022613)3.09921367
73translational initiation (GO:0006413)3.09696477
74negative regulation of membrane potential (GO:0045837)3.09326120
75lymphocyte apoptotic process (GO:0070227)3.07333982
76rRNA methylation (GO:0031167)3.05138562
77ubiquinone biosynthetic process (GO:0006744)3.04310453
78pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.03656687
79RNA methylation (GO:0001510)3.02977725
80CTP metabolic process (GO:0046036)3.02015497
81CTP biosynthetic process (GO:0006241)3.02015497
82mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.01851278
83cellular protein complex disassembly (GO:0043624)3.00396084
84pseudouridine synthesis (GO:0001522)2.99513865
85respiratory chain complex IV assembly (GO:0008535)2.99339022
86platelet dense granule organization (GO:0060155)2.99158971
87positive regulation of response to DNA damage stimulus (GO:2001022)2.96430427
88negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.95715276
89GDP-mannose metabolic process (GO:0019673)2.95560328
90telomere maintenance via recombination (GO:0000722)2.94429167
91positive regulation of translation (GO:0045727)2.93985943
92regulation of translational termination (GO:0006449)2.92863377
93regulation of signal transduction by p53 class mediator (GO:1901796)2.92717864
94regulation of nuclear cell cycle DNA replication (GO:0033262)2.90466757
95RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.89765000
96guanosine-containing compound biosynthetic process (GO:1901070)2.89648524
97respiratory electron transport chain (GO:0022904)2.89470837
98regulation of necrotic cell death (GO:0010939)2.88891364
99RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.86473798
100tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.86473798
101purine ribonucleotide transport (GO:0015868)2.86164903
102pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.86149031
103GTP biosynthetic process (GO:0006183)2.85577457
104regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.82071258
105electron transport chain (GO:0022900)2.81857738
106RNA capping (GO:0036260)2.80224762
1077-methylguanosine RNA capping (GO:0009452)2.80224762
108L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.79911521
109pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.79360002
1107-methylguanosine mRNA capping (GO:0006370)2.79225622
111pentose metabolic process (GO:0019321)2.78946261
112necroptotic process (GO:0070266)2.78872442
113exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.78733101
114DNA packaging (GO:0006323)2.78392112
115tRNA modification (GO:0006400)2.77910753
116cytochrome complex assembly (GO:0017004)2.77784893
117metallo-sulfur cluster assembly (GO:0031163)2.76967441
118iron-sulfur cluster assembly (GO:0016226)2.76967441
119adenine nucleotide transport (GO:0051503)2.75414968
120telomere maintenance via telomere lengthening (GO:0010833)2.74835260
121rRNA processing (GO:0006364)2.73755040
122nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.72124095
123DNA strand elongation involved in DNA replication (GO:0006271)2.71542279
124DNA strand elongation (GO:0022616)2.70484447
125termination of RNA polymerase I transcription (GO:0006363)2.68647780
126intra-S DNA damage checkpoint (GO:0031573)2.67973994
127regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.66119956
128UTP biosynthetic process (GO:0006228)2.65435734
129nuclear-transcribed mRNA catabolic process (GO:0000956)2.65008659
130rRNA metabolic process (GO:0016072)2.64301312
131cellular component biogenesis (GO:0044085)2.62984648
132viral mRNA export from host cell nucleus (GO:0046784)2.62088354
133transcription from RNA polymerase I promoter (GO:0006360)2.61368638
134GMP metabolic process (GO:0046037)2.60845307
135antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.59311642
136mRNA catabolic process (GO:0006402)2.57837761
137transcription elongation from RNA polymerase I promoter (GO:0006362)2.57316711
138definitive hemopoiesis (GO:0060216)2.56345769
139protein complex disassembly (GO:0043241)2.55705948
140protein targeting to membrane (GO:0006612)2.54843710
141antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.53863105
142transcription-coupled nucleotide-excision repair (GO:0006283)2.53839162
143formation of translation preinitiation complex (GO:0001731)2.52999019
144negative regulation of transcription by competitive promoter binding (GO:0010944)2.52741214
145mitotic recombination (GO:0006312)2.51591441
146pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.49974459
147macromolecular complex disassembly (GO:0032984)2.48783088
148tRNA processing (GO:0008033)2.48467390
149antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.45157871
150RNA catabolic process (GO:0006401)2.44010356
151nucleobase biosynthetic process (GO:0046112)2.42311202
152dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.41954300
153G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.41600552
154ribosome biogenesis (GO:0042254)2.41331255
155RNA modification (GO:0009451)2.39803196
156purine nucleobase biosynthetic process (GO:0009113)2.37779318
157ncRNA processing (GO:0034470)2.36285182
158spliceosomal snRNP assembly (GO:0000387)2.33789547
159cellular response to interferon-beta (GO:0035458)2.33189964
160IMP biosynthetic process (GO:0006188)2.32408520

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.53990775
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74253339
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.59927028
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.37108186
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.33053598
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.32524407
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.19165857
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.14432054
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.98892669
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.76064460
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.67611888
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.63241736
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61389917
14VDR_23849224_ChIP-Seq_CD4+_Human2.47715157
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.47070369
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.39539534
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.37492628
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.36470299
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.33143832
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.32633502
21FOXP3_21729870_ChIP-Seq_TREG_Human2.31206818
22NOTCH1_21737748_ChIP-Seq_TLL_Human2.30435879
23FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.30385245
24CREB1_15753290_ChIP-ChIP_HEK293T_Human2.28060580
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.25116540
26MYC_19079543_ChIP-ChIP_MESCs_Mouse2.19238466
27FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.18023097
28IRF8_22096565_ChIP-ChIP_GC-B_Human2.17418368
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.16919275
30HOXB4_20404135_ChIP-ChIP_EML_Mouse2.09982059
31SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.09230895
32ERG_20887958_ChIP-Seq_HPC-7_Mouse2.07514438
33E2F1_18555785_ChIP-Seq_MESCs_Mouse2.05280613
34FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.04504496
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.03250243
36ELK1_19687146_ChIP-ChIP_HELA_Human2.03140947
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.00252700
38DCP1A_22483619_ChIP-Seq_HELA_Human2.00186865
39FOXM1_23109430_ChIP-Seq_U2OS_Human1.97534690
40E2F4_17652178_ChIP-ChIP_JURKAT_Human1.96857650
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.92364951
42XRN2_22483619_ChIP-Seq_HELA_Human1.77071627
43NELFA_20434984_ChIP-Seq_ESCs_Mouse1.76509970
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74698809
45SCL_19346495_ChIP-Seq_HPC-7_Human1.74590902
46TTF2_22483619_ChIP-Seq_HELA_Human1.68390312
47GABP_19822575_ChIP-Seq_HepG2_Human1.68146598
48SPI1_23547873_ChIP-Seq_NB4_Human1.66853734
49MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.65829624
50YY1_21170310_ChIP-Seq_MESCs_Mouse1.64461051
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.64456965
52BP1_19119308_ChIP-ChIP_Hs578T_Human1.54345327
53RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.51135431
54MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.51119070
55THAP11_20581084_ChIP-Seq_MESCs_Mouse1.50317380
56CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.50139244
57SRY_22984422_ChIP-ChIP_TESTIS_Rat1.48240530
58TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48131778
59IRF1_19129219_ChIP-ChIP_H3396_Human1.46354248
60AR_21909140_ChIP-Seq_LNCAP_Human1.44440736
61IRF8_21731497_ChIP-ChIP_J774_Mouse1.42098806
62MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.39651952
63GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.39405070
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.37011182
65STAT4_19710469_ChIP-ChIP_TH1__Mouse1.35464602
66GATA1_22025678_ChIP-Seq_K562_Human1.32280903
67CIITA_25753668_ChIP-Seq_RAJI_Human1.31422238
68KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31183469
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.30284621
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.27927603
71MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.27874899
72YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27835988
73MYCN_18555785_ChIP-Seq_MESCs_Mouse1.27101339
74DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.25558622
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.23789029
76TP63_19390658_ChIP-ChIP_HaCaT_Human1.20925285
77NANOG_18555785_ChIP-Seq_MESCs_Mouse1.20758574
78ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18070742
79POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.18013147
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.17635739
81PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.17564901
82KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.15597299
83SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.14735553
84ELK1_22589737_ChIP-Seq_MCF10A_Human1.14050743
85E2F1_21310950_ChIP-Seq_MCF-7_Human1.12118318
86RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11556042
87LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10985028
88POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10520241
89ZFX_18555785_ChIP-Seq_MESCs_Mouse1.09050763
90FOXP1_21924763_ChIP-Seq_HESCs_Human1.07241193
91CTCF_18555785_ChIP-Seq_MESCs_Mouse1.07103663
92ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06935273
93STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.05956367
94BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05421592
95TFEB_21752829_ChIP-Seq_HELA_Human1.03175794
96MYC_18940864_ChIP-ChIP_HL60_Human1.01858745
97CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.01095418
98CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.00448901
99SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00232042
100MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.99783461
101STAT3_1855785_ChIP-Seq_MESCs_Mouse0.97385324
102MYB_21317192_ChIP-Seq_ERMYB_Mouse0.97143429
103KDM5A_27292631_Chip-Seq_BREAST_Human0.96893371
104PADI4_21655091_ChIP-ChIP_MCF-7_Human0.95981545
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93968802
106CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.93773687
107ESR1_15608294_ChIP-ChIP_MCF-7_Human0.93234525
108GATA1_22383799_ChIP-Seq_G1ME_Mouse0.91276280
109GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90682450
110RUNX1_22412390_ChIP-Seq_EML_Mouse0.89940916
111POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89342087
112TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.88534527
113MYC_22102868_ChIP-Seq_BL_Human0.88244012
114SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.87961515
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87598436
116ELF5_23300383_ChIP-Seq_T47D_Human0.86531039
117CTCF_26484167_Chip-Seq_Bcells_Mouse0.85189635
118YY1_22570637_ChIP-Seq_MALME-3M_Human0.85039558
119TET1_21451524_ChIP-Seq_MESCs_Mouse0.84588538
120IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.84205015
121STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.84099381
122FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.83848271
123MYB_26560356_Chip-Seq_TH1_Human0.83306453
124FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82370480
125E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.81895806
126GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.81550378
127NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.81253481
128MYB_26560356_Chip-Seq_TH2_Human0.80720977
129CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.80644825
130RACK7_27058665_Chip-Seq_MCF-7_Human0.78673956

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue4.25722338
2MP0003806_abnormal_nucleotide_metabolis3.72005898
3MP0006035_abnormal_mitochondrial_morpho3.55484220
4MP0001661_extended_life_span3.27467142
5MP0003693_abnormal_embryo_hatching2.88292991
6MP0005410_abnormal_fertilization2.68178433
7MP0002396_abnormal_hematopoietic_system2.66922366
8MP0008058_abnormal_DNA_repair2.60281011
9MP0006292_abnormal_olfactory_placode2.55457697
10MP0001835_abnormal_antigen_presentation2.50238922
11MP0003718_maternal_effect2.43471176
12MP0005075_abnormal_melanosome_morpholog2.32682956
13MP0003136_yellow_coat_color2.22758219
14MP0003724_increased_susceptibility_to2.12798752
15MP0005174_abnormal_tail_pigmentation2.06911212
16MP0009785_altered_susceptibility_to2.04492698
17MP0002148_abnormal_hypersensitivity_rea2.04129047
18MP0000358_abnormal_cell_content/2.02635437
19MP0005671_abnormal_response_to1.99786912
20MP0009379_abnormal_foot_pigmentation1.99512725
21MP0008057_abnormal_DNA_replication1.97829670
22MP0003186_abnormal_redox_activity1.92291189
23MP0003763_abnormal_thymus_physiology1.91716119
24MP0000015_abnormal_ear_pigmentation1.89482346
25MP0008007_abnormal_cellular_replicative1.88539246
26MP0000490_abnormal_crypts_of1.84404782
27MP0003786_premature_aging1.83140484
28MP0010094_abnormal_chromosome_stability1.77702233
29MP0001188_hyperpigmentation1.66956752
30MP0003941_abnormal_skin_development1.66282394
31MP0001986_abnormal_taste_sensitivity1.65305651
32MP0004145_abnormal_muscle_electrophysio1.64186680
33MP0009333_abnormal_splenocyte_physiolog1.62716739
34MP0005025_abnormal_response_to1.59397228
35MP0002095_abnormal_skin_pigmentation1.58010898
36MP0003077_abnormal_cell_cycle1.55753487
37MP0000678_abnormal_parathyroid_gland1.53959773
38MP0000685_abnormal_immune_system1.53132877
39MP0003111_abnormal_nucleus_morphology1.51717653
40MP0002638_abnormal_pupillary_reflex1.50397316
41MP0005000_abnormal_immune_tolerance1.48992425
42MP0002132_abnormal_respiratory_system1.48144925
43MP0009250_abnormal_appendicular_skeleto1.47682690
44MP0002877_abnormal_melanocyte_morpholog1.46784307
45MP0002419_abnormal_innate_immunity1.45837210
46MP0004957_abnormal_blastocyst_morpholog1.45607247
47MP0005409_darkened_coat_color1.44149425
48MP0002452_abnormal_antigen_presenting1.43581721
49MP0001764_abnormal_homeostasis1.41130804
50MP0002723_abnormal_immune_serum1.40467687
51MP0000372_irregular_coat_pigmentation1.40393516
52MP0002420_abnormal_adaptive_immunity1.39231537
53MP0004808_abnormal_hematopoietic_stem1.39056380
54MP0004185_abnormal_adipocyte_glucose1.38835706
55MP0005379_endocrine/exocrine_gland_phen1.38695715
56MP0001819_abnormal_immune_cell1.37097259
57MP0001730_embryonic_growth_arrest1.36479304
58MP0003436_decreased_susceptibility_to1.35932508
59MP0002277_abnormal_respiratory_mucosa1.34274056
60MP0002938_white_spotting1.33981216
61MP0010155_abnormal_intestine_physiology1.33540502
62MP0001800_abnormal_humoral_immune1.33005886
63MP0004233_abnormal_muscle_weight1.32994289
64MP0005220_abnormal_exocrine_pancreas1.32316507
65MP0001853_heart_inflammation1.31860048
66MP0005503_abnormal_tendon_morphology1.27780238
67MP0000462_abnormal_digestive_system1.26614774
68MP0004381_abnormal_hair_follicle1.26218666
69MP0005083_abnormal_biliary_tract1.26086248
70MP0005332_abnormal_amino_acid1.25151139
71MP0001790_abnormal_immune_system1.25134232
72MP0005387_immune_system_phenotype1.25134232
73MP0005501_abnormal_skin_physiology1.24108437
74MP0003866_abnormal_defecation1.23912247
75MP0002160_abnormal_reproductive_system1.23720270
76MP0002398_abnormal_bone_marrow1.23080159
77MP0000465_gastrointestinal_hemorrhage1.22929403
78MP0003315_abnormal_perineum_morphology1.22785132
79MP0002405_respiratory_system_inflammati1.22297136
80MP0002837_dystrophic_cardiac_calcinosis1.22051798
81MP0001697_abnormal_embryo_size1.21978781
82MP0000613_abnormal_salivary_gland1.20893120
83MP0010307_abnormal_tumor_latency1.20708189
84MP0002166_altered_tumor_susceptibility1.20388972
85MP0003011_delayed_dark_adaptation1.20224340
86MP0005623_abnormal_meninges_morphology1.19927406
87MP0005058_abnormal_lysosome_morphology1.19777879
88MP0002796_impaired_skin_barrier1.17545843
89MP0000716_abnormal_immune_system1.17314722
90MP0005397_hematopoietic_system_phenotyp1.16738198
91MP0001545_abnormal_hematopoietic_system1.16738198
92MP0000689_abnormal_spleen_morphology1.16102188
93MP0001727_abnormal_embryo_implantation1.15900619
94MP0002009_preneoplasia1.15619452
95MP0002693_abnormal_pancreas_physiology1.15245191
96MP0003123_paternal_imprinting1.14423442
97MP0005408_hypopigmentation1.13504511
98MP0001881_abnormal_mammary_gland1.12273464
99MP0004782_abnormal_surfactant_physiolog1.09567551
100MP0002722_abnormal_immune_system1.09270084
101MP0009672_abnormal_birth_weight1.09133544
102MP0002254_reproductive_system_inflammat1.09069976
103MP0001186_pigmentation_phenotype1.09001895
104MP0002933_joint_inflammation1.08955600
105MP0002429_abnormal_blood_cell1.07813173
106MP0002163_abnormal_gland_morphology1.07588454
107MP0001919_abnormal_reproductive_system1.06688212
108MP0000350_abnormal_cell_proliferation1.06496851
109MP0000579_abnormal_nail_morphology1.04346662
110MP0005084_abnormal_gallbladder_morpholo1.04185656
111MP0009697_abnormal_copulation1.02909797
112MP0005464_abnormal_platelet_physiology1.01715804
113MP0002006_tumorigenesis1.00635240
114MP0004147_increased_porphyrin_level1.00344960
115MP0001845_abnormal_inflammatory_respons0.99607417
116MP0000681_abnormal_thyroid_gland0.99073134
117MP0010030_abnormal_orbit_morphology0.96085337
118MP0002075_abnormal_coat/hair_pigmentati0.95755973
119MP0008260_abnormal_autophagy0.95472183
120MP0010386_abnormal_urinary_bladder0.94263760
121MP0002210_abnormal_sex_determination0.93842112
122MP0008469_abnormal_protein_level0.92144930
123MP0000703_abnormal_thymus_morphology0.91641364
124MP0003943_abnormal_hepatobiliary_system0.91243545
125MP0005171_absent_coat_pigmentation0.88727458
126MP0005636_abnormal_mineral_homeostasis0.88072434
127MP0000371_diluted_coat_color0.87317075
128MP0000313_abnormal_cell_death0.86820688
129MP0002019_abnormal_tumor_incidence0.86564984
130MP0005380_embryogenesis_phenotype0.85913352
131MP0001672_abnormal_embryogenesis/_devel0.85913352
132MP0002080_prenatal_lethality0.85399010
133MP0000749_muscle_degeneration0.84708231
134MP0001243_abnormal_dermal_layer0.84216032
135MP0006072_abnormal_retinal_apoptosis0.83798743
136MP0008004_abnormal_stomach_pH0.83618440
137MP0005389_reproductive_system_phenotype0.81686721
138MP0000858_altered_metastatic_potential0.81189154
139MP0006082_CNS_inflammation0.80620184
140MP0001873_stomach_inflammation0.80593386
141MP0008932_abnormal_embryonic_tissue0.80581207
142MP0002085_abnormal_embryonic_tissue0.79593313
143MP0006036_abnormal_mitochondrial_physio0.79447088
144MP0003984_embryonic_growth_retardation0.79268253
145MP0001944_abnormal_pancreas_morphology0.77515354
146MP0002088_abnormal_embryonic_growth/wei0.77390504
147MP0005330_cardiomyopathy0.76559150
148MP0001346_abnormal_lacrimal_gland0.76266069
149MP0003137_abnormal_impulse_conducting0.75040485
150MP0000627_abnormal_mammary_gland0.74972984
151MP0008875_abnormal_xenobiotic_pharmacok0.74549854
152MP0003937_abnormal_limbs/digits/tail_de0.74323660
153MP0004215_abnormal_myocardial_fiber0.69770368
154MP0001929_abnormal_gametogenesis0.69172488
155MP0001145_abnormal_male_reproductive0.64164827
156MP0000049_abnormal_middle_ear0.63092881
157MP0005395_other_phenotype0.62918320
158MP0003448_altered_tumor_morphology0.62070568
159MP0000653_abnormal_sex_gland0.58492199
160MP0005647_abnormal_sex_gland0.57359860
161MP0000534_abnormal_ureter_morphology0.55454252

Predicted human phenotypes

RankGene SetZ-score
1Cerebral hypomyelination (HP:0006808)6.74070203
2Premature ovarian failure (HP:0008209)4.43514825
3Secondary amenorrhea (HP:0000869)4.21233516
4Testicular atrophy (HP:0000029)4.19130484
5Type I transferrin isoform profile (HP:0003642)4.13409034
6Reticulocytopenia (HP:0001896)3.99218741
7Abnormal number of erythroid precursors (HP:0012131)3.83318781
8Abnormality of cells of the erythroid lineage (HP:0012130)3.80072422
9Acute necrotizing encephalopathy (HP:0006965)3.58016665
10Aplastic anemia (HP:0001915)3.52673675
11Acute encephalopathy (HP:0006846)3.41859637
12Abnormal mitochondria in muscle tissue (HP:0008316)3.37928595
13Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.26251507
14Abnormal protein N-linked glycosylation (HP:0012347)3.26251507
15Abnormal protein glycosylation (HP:0012346)3.26251507
16Abnormal glycosylation (HP:0012345)3.26251507
17Abnormal trabecular bone morphology (HP:0100671)3.22643751
18Delusions (HP:0000746)3.19894662
19Reduced antithrombin III activity (HP:0001976)3.18926380
20Microvesicular hepatic steatosis (HP:0001414)3.11996245
21CNS hypomyelination (HP:0003429)3.10970797
22Concave nail (HP:0001598)3.08306261
23Aplasia/Hypoplasia of the sacrum (HP:0008517)3.04410780
24Increased intramyocellular lipid droplets (HP:0012240)3.01181252
25Chromsome breakage (HP:0040012)2.89412171
26Vacuolated lymphocytes (HP:0001922)2.78037530
27Increased muscle lipid content (HP:0009058)2.77440728
283-Methylglutaconic aciduria (HP:0003535)2.76954020
29Progressive macrocephaly (HP:0004481)2.75730996
30Thrombocytosis (HP:0001894)2.74564105
31Absent rod-and cone-mediated responses on ERG (HP:0007688)2.70488362
3211 pairs of ribs (HP:0000878)2.68687024
33Prolonged neonatal jaundice (HP:0006579)2.67062762
34Aplasia of the musculature (HP:0100854)2.66859557
35Postnatal microcephaly (HP:0005484)2.64409201
36Chromosomal breakage induced by crosslinking agents (HP:0003221)2.62659501
37Unsteady gait (HP:0002317)2.62275754
38Multiple enchondromatosis (HP:0005701)2.62190084
39Abnormality of the renal collecting system (HP:0004742)2.57658281
40Pallor (HP:0000980)2.56677986
41Delayed epiphyseal ossification (HP:0002663)2.54258585
42Decreased activity of mitochondrial respiratory chain (HP:0008972)2.50206166
43Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.50206166
44Small epiphyses (HP:0010585)2.49338850
45Lactic acidosis (HP:0003128)2.46711701
46Progressive muscle weakness (HP:0003323)2.46609279
47Generalized aminoaciduria (HP:0002909)2.46153682
48Patchy hypopigmentation of hair (HP:0011365)2.45359439
49Increased hepatocellular lipid droplets (HP:0006565)2.43577367
50Cerebral edema (HP:0002181)2.43140682
51Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.41454508
52Carpal bone hypoplasia (HP:0001498)2.41436236
53IgM deficiency (HP:0002850)2.41117620
54Hepatic necrosis (HP:0002605)2.40509030
55Lethargy (HP:0001254)2.40053889
56Personality changes (HP:0000751)2.40046504
57Macrocytic anemia (HP:0001972)2.39979930
58Methylmalonic aciduria (HP:0012120)2.37516946
59Abnormal number of incisors (HP:0011064)2.36942305
60Abnormality of cochlea (HP:0000375)2.33296419
61Petechiae (HP:0000967)2.32540699
62Exertional dyspnea (HP:0002875)2.31954662
63Renal Fanconi syndrome (HP:0001994)2.29243158
64Exercise intolerance (HP:0003546)2.29139403
65CNS demyelination (HP:0007305)2.28192064
66Pancytopenia (HP:0001876)2.26484633
67Intestinal atresia (HP:0011100)2.26259280
68Lipid accumulation in hepatocytes (HP:0006561)2.25332173
69Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.25320917
70True hermaphroditism (HP:0010459)2.24024979
71Hepatocellular necrosis (HP:0001404)2.21196233
72Cellular immunodeficiency (HP:0005374)2.19752332
73Type 2 muscle fiber atrophy (HP:0003554)2.18601525
74White forelock (HP:0002211)2.17539805
75Aplasia/hypoplasia of the uterus (HP:0008684)2.14836088
76Recurrent abscess formation (HP:0002722)2.14181178
77Abnormality of the preputium (HP:0100587)2.14006934
78Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.13497328
79Myelodysplasia (HP:0002863)2.12148161
80Duplicated collecting system (HP:0000081)2.11414878
81Respiratory failure (HP:0002878)2.10839913
82Cleft eyelid (HP:0000625)2.10398305
83Aplasia/Hypoplasia involving the musculature (HP:0001460)2.09581160
84Methylmalonic acidemia (HP:0002912)2.08534969
85Hyperglycinemia (HP:0002154)2.08006141
86Abnormality of placental membranes (HP:0011409)2.07171189
87Amniotic constriction ring (HP:0009775)2.07171189
88Abnormality of reticulocytes (HP:0004312)2.05691884
89Renal tubular dysfunction (HP:0000124)2.04506988
90Emotional lability (HP:0000712)2.04350880
91Renal cortical cysts (HP:0000803)2.03363614
92Facial cleft (HP:0002006)2.03235117
93Increased serum lactate (HP:0002151)2.03010352
94Abnormal rod and cone electroretinograms (HP:0008323)2.02252851
95Muscle fiber atrophy (HP:0100295)2.01713167
96Aplasia/Hypoplasia of the fovea (HP:0008060)2.01712179
97Hypoplasia of the fovea (HP:0007750)2.01712179
98Pancreatic cysts (HP:0001737)1.98249399
99Prolonged bleeding time (HP:0003010)1.97557378
100Aplasia/Hypoplasia of the patella (HP:0006498)1.96819941
101Absent thumb (HP:0009777)1.95811528
102Clubbing of toes (HP:0100760)1.95793753
103Degeneration of anterior horn cells (HP:0002398)1.94725257
104Abnormality of the anterior horn cell (HP:0006802)1.94725257
105Selective tooth agenesis (HP:0001592)1.94529730
106Bone marrow hypocellularity (HP:0005528)1.94315087
107Abnormality of renal resorption (HP:0011038)1.94309702
108Premature graying of hair (HP:0002216)1.94129515
109Elevated erythrocyte sedimentation rate (HP:0003565)1.93873994
110Abnormality of chromosome stability (HP:0003220)1.92813866
111Hypothermia (HP:0002045)1.92644367
112Pendular nystagmus (HP:0012043)1.92330467
113Meckel diverticulum (HP:0002245)1.92224580
114Abnormality of T cell physiology (HP:0011840)1.91139618
115Abnormality of DNA repair (HP:0003254)1.90468635
116Mitochondrial inheritance (HP:0001427)1.90190574
117Abnormality of methionine metabolism (HP:0010901)1.90183721
118Rough bone trabeculation (HP:0100670)1.89436720
119Hypergonadotropic hypogonadism (HP:0000815)1.89433494
120Sparse eyelashes (HP:0000653)1.88857267
121Patellar aplasia (HP:0006443)1.88329458
122Ileus (HP:0002595)1.86451725
123Abnormal hemoglobin (HP:0011902)1.86265609
124Abnormality of the ileum (HP:0001549)1.84251956
125Horseshoe kidney (HP:0000085)1.82778898
126Poor head control (HP:0002421)1.82368346
127Trismus (HP:0000211)1.81272837
128Lymphoma (HP:0002665)1.80367384
129Blindness (HP:0000618)1.78129810
130Birth length less than 3rd percentile (HP:0003561)1.78122928
131Abnormality of glycolysis (HP:0004366)1.77160466
132Attenuation of retinal blood vessels (HP:0007843)1.76915881
133Glycosuria (HP:0003076)1.76838629
134Abnormality of urine glucose concentration (HP:0011016)1.76838629
135Pancreatic fibrosis (HP:0100732)1.74974787
136Oral leukoplakia (HP:0002745)1.74599763
137Asplenia (HP:0001746)1.74511729
138Irregular epiphyses (HP:0010582)1.74445028
139Neutropenia (HP:0001875)1.74149093
140Abnormal delayed hypersensitivity skin test (HP:0002963)1.73320193
141Aplasia/Hypoplasia of the uvula (HP:0010293)1.73220387
142Respiratory difficulties (HP:0002880)1.73088149
143Increased CSF lactate (HP:0002490)1.72913566
144Hypoplasia of the uterus (HP:0000013)1.72235676
145Microretrognathia (HP:0000308)1.71239429
146Rectal fistula (HP:0100590)1.69683785
147Rectovaginal fistula (HP:0000143)1.69683785
148Aplasia/Hypoplasia of the spleen (HP:0010451)1.64461484
149Poikiloderma (HP:0001029)1.63874395
150Increased neuronal autofluorescent lipopigment (HP:0002074)1.62667714
151Abnormality of macrophages (HP:0004311)1.62349908
152Abnormality of the fovea (HP:0000493)1.62144221
153Myositis (HP:0100614)1.61650845
154Vaginal fistula (HP:0004320)1.60479313
155Median cleft lip (HP:0000161)1.59621126
156Recurrent pneumonia (HP:0006532)1.59203542
157Nonprogressive disorder (HP:0003680)1.58580591
158Anhidrosis (HP:0000970)1.58514371

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.30326215
2IRAK33.27572755
3NME23.08552165
4IRAK42.95634298
5NEK12.68304552
6VRK22.68085305
7PIM22.35936054
8TXK2.22775156
9ZAK2.11698843
10PASK2.06884407
11VRK12.01690129
12TEC2.00890318
13MKNK12.00641838
14RIPK110.9437304
15MAPK151.99280460
16CDC71.86752171
17DAPK31.83221523
18BUB11.82824418
19FLT31.82259177
20TLK11.77104654
21WEE11.74132104
22SRPK11.72612470
23IRAK11.64215947
24PDPK11.58817448
25NEK91.56732260
26KIT1.55791632
27EIF2AK31.54044360
28TIE11.53230889
29TESK21.45792788
30BCKDK1.44354834
31PLK41.42260393
32MAP3K141.37918152
33MAP4K11.36706451
34BTK1.36565780
35MUSK1.32671389
36IKBKB1.31963946
37NLK1.31016899
38NUAK11.29065660
39MKNK21.28575704
40ZAP701.28348712
41IKBKE1.24948466
42CDK81.23690508
43ACVR1B1.22335283
44BRSK21.21190592
45EPHA21.21033133
46JAK31.17234923
47NEK61.15295030
48ARAF1.15226170
49IRAK21.14945795
50EIF2AK21.14776309
51STK38L1.13893425
52EIF2AK11.13318910
53MAPKAPK31.12436714
54PRKCG1.09291984
55TRIB31.06146814
56CDK71.03220901
57PIM11.02891389
58MAPKAPK51.01635273
59ADRBK21.00669339
60INSRR0.97055647
61RPS6KB20.96192553
62MAP3K30.95724809
63DYRK30.95503026
64PAK40.94548164
65DAPK10.94380758
66PLK30.94130982
67PBK0.92401578
68ATR0.91985484
69TAF10.91965329
70RPS6KA40.91909912
71MST40.91835676
72GRK10.91362527
73TGFBR10.90721572
74TSSK60.90381907
75TNIK0.90377851
76BLK0.90281947
77YES10.90067288
78RPS6KA50.88854704
79TESK10.88648676
80STK40.88466486
81TBK10.86004313
82MAP2K30.83226381
83KDR0.82850345
84ILK0.82493737
85AKT30.81607743
86TGFBR20.78893618
87LYN0.75281923
88TNK20.74222228
89CLK10.71877478
90TYK20.71177854
91MAP2K60.71019586
92PRKCE0.70552619
93STK240.67901023
94SMG10.67503049
95GRK70.67386152
96TAOK30.67382299
97BMPR1B0.67094695
98MAP4K20.66710592
99AURKB0.66517737
100PDK20.66277370
101CDK30.64712876
102CHUK0.63698022
103PLK10.63680018
104PRKCD0.63139501
105PRKG20.62984920
106CSNK2A10.60143376
107MYLK0.58134291
108NME10.57839702
109HIPK20.55249693
110PRKCI0.54924193
111CHEK20.53994874
112MAP3K120.52878119
113LCK0.52723642
114BRAF0.49449829
115MAP3K80.48962903
116MATK0.48036510
117SYK0.46834647
118MTOR0.46173317
119CSF1R0.45687128
120CSNK2A20.44993413
121ERN10.43946990
122TTK0.43945711
123BMPR20.43853050
124LIMK10.43520650
125PIK3CG0.42766179
126AURKA0.42279143
127STK100.41484088
128TRPM70.40965031
129MAP3K110.40729059
130PTK20.40329832
131PRKCZ0.38613825
132DMPK0.38051846
133CHEK10.37144826
134FGR0.35795711
135PAK10.35735620
136MST1R0.33801411
137ERBB40.33657797
138BRSK10.33351251
139CSNK1G30.26739323
140ABL20.26373360
141CDK11A0.24023773
142TAOK20.23790561
143CDK150.23602699
144CDK140.23297136
145WNK40.22846594
146CCNB10.21151595
147PRKCB0.21126503
148CDK180.21050622
149AKT20.20987824
150DYRK20.20756346
151ATM0.19978882
152PRKCQ0.19214130
153CDK10.19117554

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.10192776
2Protein export_Homo sapiens_hsa030603.55857587
3DNA replication_Homo sapiens_hsa030303.25364120
4RNA polymerase_Homo sapiens_hsa030203.05417440
5Tyrosine metabolism_Homo sapiens_hsa003502.99771053
6Mismatch repair_Homo sapiens_hsa034302.74892937
7Homologous recombination_Homo sapiens_hsa034402.63272477
8Base excision repair_Homo sapiens_hsa034102.42838173
9Proteasome_Homo sapiens_hsa030502.42502944
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.32083639
11Pyrimidine metabolism_Homo sapiens_hsa002402.30879371
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.15642783
13Nucleotide excision repair_Homo sapiens_hsa034202.12708478
14Fanconi anemia pathway_Homo sapiens_hsa034602.04283938
15Spliceosome_Homo sapiens_hsa030402.02781151
16Basal transcription factors_Homo sapiens_hsa030222.02251858
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.83520352
18Non-homologous end-joining_Homo sapiens_hsa034501.77761825
19Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.65169285
20Other glycan degradation_Homo sapiens_hsa005111.64958300
21Folate biosynthesis_Homo sapiens_hsa007901.58068118
22RNA degradation_Homo sapiens_hsa030181.55669509
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.48544249
24Purine metabolism_Homo sapiens_hsa002301.42732980
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.41905467
26Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.38146155
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.38099192
28Lysine degradation_Homo sapiens_hsa003101.37055939
29Arachidonic acid metabolism_Homo sapiens_hsa005901.34558320
30RNA transport_Homo sapiens_hsa030131.32329121
31One carbon pool by folate_Homo sapiens_hsa006701.26694121
32Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.24084258
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23766723
34Primary immunodeficiency_Homo sapiens_hsa053401.19631581
35Pentose phosphate pathway_Homo sapiens_hsa000301.16132565
36Fatty acid metabolism_Homo sapiens_hsa012121.16043082
37Herpes simplex infection_Homo sapiens_hsa051681.15292971
38RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.11447286
39NF-kappa B signaling pathway_Homo sapiens_hsa040641.10599449
40N-Glycan biosynthesis_Homo sapiens_hsa005101.08733218
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.07662353
42Antigen processing and presentation_Homo sapiens_hsa046121.03735946
43Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01885059
44Oxidative phosphorylation_Homo sapiens_hsa001901.00873315
45Cell cycle_Homo sapiens_hsa041100.97615397
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.97578840
47Cardiac muscle contraction_Homo sapiens_hsa042600.96201005
48Cysteine and methionine metabolism_Homo sapiens_hsa002700.94762420
49Legionellosis_Homo sapiens_hsa051340.94541515
50Sulfur relay system_Homo sapiens_hsa041220.93881957
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.93511158
52Hematopoietic cell lineage_Homo sapiens_hsa046400.93509262
53Glycosaminoglycan degradation_Homo sapiens_hsa005310.92764058
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92145119
55Parkinsons disease_Homo sapiens_hsa050120.91873892
56Pyruvate metabolism_Homo sapiens_hsa006200.89872788
57Vitamin B6 metabolism_Homo sapiens_hsa007500.89279117
58Biosynthesis of amino acids_Homo sapiens_hsa012300.89231417
59Pentose and glucuronate interconversions_Homo sapiens_hsa000400.88363094
60Measles_Homo sapiens_hsa051620.87842132
61p53 signaling pathway_Homo sapiens_hsa041150.87464630
62Galactose metabolism_Homo sapiens_hsa000520.86896314
63Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.86416139
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.83625650
65Huntingtons disease_Homo sapiens_hsa050160.79546401
66Carbon metabolism_Homo sapiens_hsa012000.78380657
67Drug metabolism - other enzymes_Homo sapiens_hsa009830.78258668
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77270331
69NOD-like receptor signaling pathway_Homo sapiens_hsa046210.76428911
70mTOR signaling pathway_Homo sapiens_hsa041500.76288487
71Glutathione metabolism_Homo sapiens_hsa004800.75745104
72ErbB signaling pathway_Homo sapiens_hsa040120.75625523
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75058205
742-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.74200164
75Sphingolipid metabolism_Homo sapiens_hsa006000.73811480
76Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73533353
77Epstein-Barr virus infection_Homo sapiens_hsa051690.72908998
78Allograft rejection_Homo sapiens_hsa053300.72304019
79TGF-beta signaling pathway_Homo sapiens_hsa043500.71169511
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69455236
81Fatty acid degradation_Homo sapiens_hsa000710.69143213
82Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.68876700
83Peroxisome_Homo sapiens_hsa041460.65885147
84Leishmaniasis_Homo sapiens_hsa051400.65757246
85Regulation of autophagy_Homo sapiens_hsa041400.63595352
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63394252
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63025421
88Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61867523
89Steroid biosynthesis_Homo sapiens_hsa001000.61584303
90Graft-versus-host disease_Homo sapiens_hsa053320.60428845
91Selenocompound metabolism_Homo sapiens_hsa004500.60135622
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.59626364
93Autoimmune thyroid disease_Homo sapiens_hsa053200.58990395
94Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.57569246
95Toll-like receptor signaling pathway_Homo sapiens_hsa046200.56613930
96Fatty acid elongation_Homo sapiens_hsa000620.54444193
97Lysosome_Homo sapiens_hsa041420.53741836
98Propanoate metabolism_Homo sapiens_hsa006400.52660822
99Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52207768
100Metabolic pathways_Homo sapiens_hsa011000.51407740
101Linoleic acid metabolism_Homo sapiens_hsa005910.50729330
102Apoptosis_Homo sapiens_hsa042100.49198133
103Sulfur metabolism_Homo sapiens_hsa009200.47847284
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47533965
105Acute myeloid leukemia_Homo sapiens_hsa052210.47323569
106Influenza A_Homo sapiens_hsa051640.45684283
107Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.44465115
108Alzheimers disease_Homo sapiens_hsa050100.44406233
109mRNA surveillance pathway_Homo sapiens_hsa030150.41658967
110Malaria_Homo sapiens_hsa051440.41631890
111HIF-1 signaling pathway_Homo sapiens_hsa040660.41460284
112Vitamin digestion and absorption_Homo sapiens_hsa049770.40568165
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.40159521
114Pertussis_Homo sapiens_hsa051330.39571995
115Tight junction_Homo sapiens_hsa045300.38472181
116Type I diabetes mellitus_Homo sapiens_hsa049400.38383438
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38150911
118Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37306686
119Ether lipid metabolism_Homo sapiens_hsa005650.36982963
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36000880
121Fructose and mannose metabolism_Homo sapiens_hsa000510.35844217
122Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35402595
123Asthma_Homo sapiens_hsa053100.34202613
124Systemic lupus erythematosus_Homo sapiens_hsa053220.33524069
125Rheumatoid arthritis_Homo sapiens_hsa053230.32984491
126Fat digestion and absorption_Homo sapiens_hsa049750.31652607
127Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.30736043
128Thyroid cancer_Homo sapiens_hsa052160.29783823
129B cell receptor signaling pathway_Homo sapiens_hsa046620.29362446
130Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29221134
131Shigellosis_Homo sapiens_hsa051310.29072709
132Tryptophan metabolism_Homo sapiens_hsa003800.28985391
133Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.28984943
134Mineral absorption_Homo sapiens_hsa049780.28255726
135Chemical carcinogenesis_Homo sapiens_hsa052040.28243388
136Hepatitis C_Homo sapiens_hsa051600.27720267
137Starch and sucrose metabolism_Homo sapiens_hsa005000.26641709
138Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26630350
139beta-Alanine metabolism_Homo sapiens_hsa004100.25240335
140Arginine and proline metabolism_Homo sapiens_hsa003300.24308303
141Central carbon metabolism in cancer_Homo sapiens_hsa052300.22944066

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »