EFCAB10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axoneme assembly (GO:0035082)9.68823466
2GTP biosynthetic process (GO:0006183)9.29183142
3nucleoside diphosphate phosphorylation (GO:0006165)9.05849669
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.70763250
5UTP biosynthetic process (GO:0006228)8.24113392
6ventricular system development (GO:0021591)7.83201587
7UTP metabolic process (GO:0046051)7.38281590
8motile cilium assembly (GO:0044458)6.61208765
9guanosine-containing compound biosynthetic process (GO:1901070)6.55933582
10regulation of cilium movement (GO:0003352)6.38007875
11CTP metabolic process (GO:0046036)6.21109355
12CTP biosynthetic process (GO:0006241)6.21109355
13intraciliary transport (GO:0042073)6.19690618
14pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.64596458
15sperm motility (GO:0030317)5.51493593
16left/right axis specification (GO:0070986)5.31409010
17cell wall macromolecule metabolic process (GO:0044036)5.25301333
18cell wall macromolecule catabolic process (GO:0016998)5.25301333
19pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.16442415
20cilium organization (GO:0044782)5.15719373
21fusion of sperm to egg plasma membrane (GO:0007342)5.03590612
22protein localization to cilium (GO:0061512)5.02791031
23nucleotide phosphorylation (GO:0046939)4.99037975
24pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.94748956
25cilium assembly (GO:0042384)4.92422861
26acrosome reaction (GO:0007340)4.82870782
27acrosome assembly (GO:0001675)4.68816635
28cilium morphogenesis (GO:0060271)4.67790743
29microtubule bundle formation (GO:0001578)4.66061982
30sperm-egg recognition (GO:0035036)4.56461891
31purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.47359504
32sensory perception of smell (GO:0007608)4.38461247
33multicellular organism reproduction (GO:0032504)4.37624106
34nucleoside diphosphate metabolic process (GO:0009132)4.37290160
35purine nucleoside triphosphate biosynthetic process (GO:0009145)4.34497305
36pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.26893572
37cellular component assembly involved in morphogenesis (GO:0010927)4.22852453
38binding of sperm to zona pellucida (GO:0007339)4.21020535
39microtubule-based movement (GO:0007018)4.19800603
40single fertilization (GO:0007338)4.06452568
41retinal cone cell development (GO:0046549)4.04882197
42spermatid nucleus differentiation (GO:0007289)4.03926053
43spermatid development (GO:0007286)4.03869159
44cell-cell recognition (GO:0009988)4.01690353
45plasma membrane fusion (GO:0045026)3.99336497
46regulation of meiosis I (GO:0060631)3.94152543
47microtubule severing (GO:0051013)3.93303875
48regulation of microtubule-based movement (GO:0060632)3.92011437
49ribonucleoside triphosphate biosynthetic process (GO:0009201)3.86165863
50nucleoside triphosphate biosynthetic process (GO:0009142)3.85641604
51pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.83548578
52piRNA metabolic process (GO:0034587)3.77405904
53pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.75981278
54protein polyglutamylation (GO:0018095)3.73286835
55oxygen transport (GO:0015671)3.72613251
56deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.68080496
57reproduction (GO:0000003)3.58004875
58negative regulation of inclusion body assembly (GO:0090084)3.54145365
59mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.53457779
60nonmotile primary cilium assembly (GO:0035058)3.53165611
61calcium ion-dependent exocytosis (GO:0017156)3.50599290
62microtubule depolymerization (GO:0007019)3.49194197
63mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.48511790
64meiotic cell cycle (GO:0051321)3.47483506
65DNA methylation involved in gamete generation (GO:0043046)3.45308268
66ADP metabolic process (GO:0046031)3.42556153
67detection of calcium ion (GO:0005513)3.41578853
68ATP synthesis coupled proton transport (GO:0015986)3.37325060
69energy coupled proton transport, down electrochemical gradient (GO:0015985)3.37325060
70sperm capacitation (GO:0048240)3.30938671
71cell projection assembly (GO:0030031)3.29573200
72pyrimidine ribonucleotide metabolic process (GO:0009218)3.26873096
73diterpenoid biosynthetic process (GO:0016102)3.25199790
74regulation of female gonad development (GO:2000194)3.23885174
75intra-S DNA damage checkpoint (GO:0031573)3.17355533
76positive regulation of histone H3-K4 methylation (GO:0051571)3.13431241
77pyrimidine nucleotide biosynthetic process (GO:0006221)3.12481207
78regulation of DNA methylation (GO:0044030)3.11502973
79synapsis (GO:0007129)3.10292993
80ATP biosynthetic process (GO:0006754)3.09695608
81fertilization (GO:0009566)3.02620900
82sensory perception of chemical stimulus (GO:0007606)3.01948793
83neuron cell-cell adhesion (GO:0007158)3.01779972
84microtubule polymerization or depolymerization (GO:0031109)3.01702904
85terpenoid biosynthetic process (GO:0016114)2.99906185
86centriole replication (GO:0007099)2.95693551
87determination of left/right symmetry (GO:0007368)2.92877459
88left/right pattern formation (GO:0060972)2.92044441
89electron transport chain (GO:0022900)2.91057396
90centriole assembly (GO:0098534)2.90594784
91replication fork processing (GO:0031297)2.89620540
92vitamin transmembrane transport (GO:0035461)2.89185427
93brain morphogenesis (GO:0048854)2.88797936
94male meiosis I (GO:0007141)2.88534278
95protein localization to synapse (GO:0035418)2.88120950
96pyrimidine ribonucleoside metabolic process (GO:0046131)2.87526446
97respiratory electron transport chain (GO:0022904)2.84459551
98regulation of inclusion body assembly (GO:0090083)2.83971456
99proline transport (GO:0015824)2.83196397
100reciprocal DNA recombination (GO:0035825)2.79613140
101reciprocal meiotic recombination (GO:0007131)2.79613140
102establishment of protein localization to mitochondrial membrane (GO:0090151)2.76769717
103positive regulation of gastrulation (GO:2000543)2.76679958
104determination of bilateral symmetry (GO:0009855)2.76250507
105negative regulation of T cell differentiation in thymus (GO:0033085)2.76061050
106resolution of meiotic recombination intermediates (GO:0000712)2.75709570
107cell recognition (GO:0008037)2.72520148
108primary alcohol catabolic process (GO:0034310)2.70217348
109specification of symmetry (GO:0009799)2.69204945
110phosphorelay signal transduction system (GO:0000160)2.67849559
111spermatogenesis (GO:0007283)2.66869512
112regulation of protein kinase A signaling (GO:0010738)2.65480038
113male gamete generation (GO:0048232)2.65133788
114protein complex biogenesis (GO:0070271)2.61541148
115pyrimidine-containing compound transmembrane transport (GO:0072531)2.61496958
116lateral ventricle development (GO:0021670)2.61086550
117gas transport (GO:0015669)2.60372001
118negative regulation of DNA-dependent DNA replication (GO:2000104)2.57691758
119chromatin remodeling at centromere (GO:0031055)2.56887496
120mitochondrial respiratory chain complex I assembly (GO:0032981)2.56391137
121NADH dehydrogenase complex assembly (GO:0010257)2.56391137
122mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.56391137
123pyrimidine nucleoside biosynthetic process (GO:0046134)2.55795653
124retinal rod cell development (GO:0046548)2.55737482
125base-excision repair, AP site formation (GO:0006285)2.54973031
126male meiosis (GO:0007140)2.54466953
127female mating behavior (GO:0060180)2.54446641
128response to pheromone (GO:0019236)2.53613238
129photoreceptor cell maintenance (GO:0045494)2.52518340
130glutathione derivative biosynthetic process (GO:1901687)2.48193436
131glutathione derivative metabolic process (GO:1901685)2.48193436
132synaptonemal complex organization (GO:0070193)2.48051878
133smoothened signaling pathway (GO:0007224)2.47002507
134CENP-A containing nucleosome assembly (GO:0034080)2.46629248
135mitochondrial respiratory chain complex assembly (GO:0033108)2.46328011
136recombinational repair (GO:0000725)2.45200524
137double-strand break repair via homologous recombination (GO:0000724)2.45125730
138detection of light stimulus involved in visual perception (GO:0050908)2.44526560
139detection of light stimulus involved in sensory perception (GO:0050962)2.44526560
140maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.44503827
141water-soluble vitamin biosynthetic process (GO:0042364)2.43247979
142behavioral response to nicotine (GO:0035095)2.43027760
143photoreceptor cell development (GO:0042461)2.42825033
144gene silencing by RNA (GO:0031047)2.41735528
145mismatch repair (GO:0006298)2.41638277
146organelle assembly (GO:0070925)2.41522060
147aldehyde catabolic process (GO:0046185)2.41268923
148female gamete generation (GO:0007292)2.41203481
149one-carbon compound transport (GO:0019755)2.35630607
150negative regulation of transcription regulatory region DNA binding (GO:2000678)2.35125363
151meiosis I (GO:0007127)2.34750668
152regulation of acrosome reaction (GO:0060046)2.33403802
153rRNA modification (GO:0000154)2.33224160
154cilium movement (GO:0003341)13.2215756
155axonemal dynein complex assembly (GO:0070286)11.7714205
156cilium or flagellum-dependent cell motility (GO:0001539)11.1086203
157epithelial cilium movement (GO:0003351)10.7783026

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.57090908
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.14495566
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.09982428
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.02519325
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.81032893
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.57159969
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.41449836
8CTBP2_25329375_ChIP-Seq_LNCAP_Human2.41128764
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.40674062
10TAF15_26573619_Chip-Seq_HEK293_Human2.40159362
11EWS_26573619_Chip-Seq_HEK293_Human2.31782031
12GBX2_23144817_ChIP-Seq_PC3_Human2.29549059
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.26314357
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19180635
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.18903926
16VDR_22108803_ChIP-Seq_LS180_Human2.10299831
17RBPJ_22232070_ChIP-Seq_NCS_Mouse2.05948201
18* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.04300907
19CBX2_27304074_Chip-Seq_ESCs_Mouse2.04108337
20RNF2_27304074_Chip-Seq_NSC_Mouse2.03569072
21KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.02776493
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.01028562
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.00396897
24REST_21632747_ChIP-Seq_MESCs_Mouse1.99231613
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.96638061
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.94402549
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88315598
28P300_19829295_ChIP-Seq_ESCs_Human1.84806158
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.82158013
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.80737310
31IGF1R_20145208_ChIP-Seq_DFB_Human1.77498205
32* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.76043900
33SMAD4_21799915_ChIP-Seq_A2780_Human1.72651474
34POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.64945961
35TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64945961
36IRF1_19129219_ChIP-ChIP_H3396_Human1.63096816
37GATA1_26923725_Chip-Seq_HPCs_Mouse1.60871407
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.59138579
39POU3F2_20337985_ChIP-ChIP_501MEL_Human1.58544273
40TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.58492583
41SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.58359296
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57945860
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56398049
44SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.55315289
45* ER_23166858_ChIP-Seq_MCF-7_Human1.54648533
46SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.54048681
47SUZ12_27294783_Chip-Seq_ESCs_Mouse1.54027823
48EZH2_27304074_Chip-Seq_ESCs_Mouse1.49520129
49EZH2_27294783_Chip-Seq_ESCs_Mouse1.49343929
50JARID2_20064375_ChIP-Seq_MESCs_Mouse1.47458916
51STAT3_23295773_ChIP-Seq_U87_Human1.47348463
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.47015628
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.46474942
54EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.45732361
55TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43225236
56FUS_26573619_Chip-Seq_HEK293_Human1.43095577
57ELK1_19687146_ChIP-ChIP_HELA_Human1.43072073
58TCF4_23295773_ChIP-Seq_U87_Human1.42519866
59NANOG_18555785_Chip-Seq_ESCs_Mouse1.41904143
60CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40792472
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.37364260
62MYC_18940864_ChIP-ChIP_HL60_Human1.37224115
63BCAT_22108803_ChIP-Seq_LS180_Human1.36852210
64TCF4_22108803_ChIP-Seq_LS180_Human1.36621493
65CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36582073
66MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.36505044
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.35044282
68* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.34785775
69SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.34198151
70SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.34113909
71FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34037990
72FOXA1_25329375_ChIP-Seq_VCAP_Human1.34037990
73ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32668212
74MTF2_20144788_ChIP-Seq_MESCs_Mouse1.31557838
75KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.31555221
76KDM2B_26808549_Chip-Seq_REH_Human1.30939561
77SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30275907
78SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.30069153
79NANOG_19829295_ChIP-Seq_ESCs_Human1.29238475
80SOX2_19829295_ChIP-Seq_ESCs_Human1.29238475
81* FLI1_21867929_ChIP-Seq_TH2_Mouse1.29159743
82SMAD3_21741376_ChIP-Seq_EPCs_Human1.28632439
83DROSHA_22980978_ChIP-Seq_HELA_Human1.27995092
84SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.27790541
85SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.27562637
86RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.26846899
87CBP_20019798_ChIP-Seq_JUKART_Human1.25827282
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25827282
89TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.24935020
90NFE2_27457419_Chip-Seq_LIVER_Mouse1.24879438
91* TAL1_26923725_Chip-Seq_HPCs_Mouse1.24832317
92MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24828925
93CMYC_18555785_Chip-Seq_ESCs_Mouse1.24584512
94JARID2_20075857_ChIP-Seq_MESCs_Mouse1.24492106
95P53_22387025_ChIP-Seq_ESCs_Mouse1.24384583
96SOX2_18555785_Chip-Seq_ESCs_Mouse1.24273274
97PIAS1_25552417_ChIP-Seq_VCAP_Human1.24244176
98FOXM1_26456572_ChIP-Seq_MCF-7_Human1.24179890
99* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23844245
100E2F4_17652178_ChIP-ChIP_JURKAT_Human1.23495709
101PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23452843
102AR_25329375_ChIP-Seq_VCAP_Human1.23226523
103EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.22510710
104ZNF274_21170338_ChIP-Seq_K562_Hela1.22485547
105CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21533157
106EZH2_27294783_Chip-Seq_NPCs_Mouse1.20978319
107P300_18555785_Chip-Seq_ESCs_Mouse1.20079135
108EED_16625203_ChIP-ChIP_MESCs_Mouse1.19806050
109* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19671456
110EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.19624458
111PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.19027666
112VDR_23849224_ChIP-Seq_CD4+_Human1.18776267
113PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18666061
114STAT3_18555785_Chip-Seq_ESCs_Mouse1.18476226
115LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18475363
116NR3C1_21868756_ChIP-Seq_MCF10A_Human1.18364431
117E2F1_18555785_Chip-Seq_ESCs_Mouse1.18018036
118PHF8_20622853_ChIP-Seq_HELA_Human1.17782074
119SUZ12_18555785_Chip-Seq_ESCs_Mouse1.15566246
120ETV1_20927104_ChIP-Seq_GIST48_Human1.15350855
121GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15297557
122TP53_22573176_ChIP-Seq_HFKS_Human1.14419897
123FOXA1_21572438_ChIP-Seq_LNCaP_Human1.13596360
124AR_20517297_ChIP-Seq_VCAP_Human1.12518691
125NCOR_22424771_ChIP-Seq_293T_Human1.12319490
126NFYB_21822215_ChIP-Seq_K562_Human1.12049867
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11907284
128JUN_21703547_ChIP-Seq_K562_Human1.11361980
129RUNX2_22187159_ChIP-Seq_PCA_Human1.11325389
130EZH2_18974828_ChIP-Seq_MESCs_Mouse1.11294820
131RNF2_18974828_ChIP-Seq_MESCs_Mouse1.11294820
132PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.10269154
133OCT4_18555785_Chip-Seq_ESCs_Mouse1.10229893
134SMAD4_21741376_ChIP-Seq_EPCs_Human1.09990317
135RUNX1_27457419_Chip-Seq_LIVER_Mouse1.09783360
136ZFX_18555785_Chip-Seq_ESCs_Mouse1.09589899
137RBPJ_21746931_ChIP-Seq_IB4_Human1.09171248
138KLF5_20875108_ChIP-Seq_MESCs_Mouse1.08850456
139MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08432919
140CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08236160
141RNF2_27304074_Chip-Seq_ESCs_Mouse1.06938966
142CRX_20693478_ChIP-Seq_RETINA_Mouse1.06736830
143CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.06733794
144PRDM14_20953172_ChIP-Seq_ESCs_Human1.04680812
145TBL1_22424771_ChIP-Seq_293T_Human1.04148308
146CDX2_22108803_ChIP-Seq_LS180_Human1.03097231
147HNFA_21074721_ChIP-Seq_CACO-2_Human0.99670436
148CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.99038475
149LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98351056
150* GATA3_21878914_ChIP-Seq_MCF-7_Human0.98256072
151NFYA_21822215_ChIP-Seq_K562_Human0.97401641
152CBX2_22325352_ChIP-Seq_293T-Rex_Human0.94504504
153* NANOG_20526341_ChIP-Seq_ESCs_Human0.93634324

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction5.15287379
2MP0005410_abnormal_fertilization4.87868950
3MP0002653_abnormal_ependyma_morphology3.69055093
4MP0003880_abnormal_central_pattern3.45023039
5MP0003718_maternal_effect3.21558644
6MP0008875_abnormal_xenobiotic_pharmacok3.14165398
7MP0005646_abnormal_pituitary_gland3.13455559
8MP0003136_yellow_coat_color3.00491770
9MP0005623_abnormal_meninges_morphology2.72780244
10MP0009046_muscle_twitch2.66365370
11MP0005423_abnormal_somatic_nervous2.42628068
12MP0006276_abnormal_autonomic_nervous2.38957357
13MP0008058_abnormal_DNA_repair2.33719017
14MP0003698_abnormal_male_reproductive2.32437296
15MP0004859_abnormal_synaptic_plasticity2.27051940
16MP0001440_abnormal_grooming_behavior2.16949475
17MP0003890_abnormal_embryonic-extraembry2.16333262
18MP0003635_abnormal_synaptic_transmissio2.13505807
19MP0009745_abnormal_behavioral_response2.10627130
20MP0002064_seizures2.05883835
21MP0002572_abnormal_emotion/affect_behav2.01055609
22MP0002272_abnormal_nervous_system2.00273171
23MP0001529_abnormal_vocalization1.99746802
24MP0002734_abnormal_mechanical_nocicepti1.99083598
25MP0009379_abnormal_foot_pigmentation1.98702618
26MP0004043_abnormal_pH_regulation1.96529067
27MP0004270_analgesia1.95031451
28MP0008057_abnormal_DNA_replication1.90989354
29MP0002132_abnormal_respiratory_system1.90579696
30MP0001968_abnormal_touch/_nociception1.90072367
31MP0002160_abnormal_reproductive_system1.87628780
32MP0005645_abnormal_hypothalamus_physiol1.86251400
33MP0002063_abnormal_learning/memory/cond1.79157006
34MP0000566_synostosis1.77807079
35MP0002735_abnormal_chemical_nociception1.77706868
36MP0002557_abnormal_social/conspecific_i1.77388021
37MP0001929_abnormal_gametogenesis1.73777584
38MP0004133_heterotaxia1.66787907
39MP0002736_abnormal_nociception_after1.66489844
40MP0001501_abnormal_sleep_pattern1.60923752
41MP0003122_maternal_imprinting1.60865530
42MP0001293_anophthalmia1.59738904
43MP0002837_dystrophic_cardiac_calcinosis1.58244928
44MP0002277_abnormal_respiratory_mucosa1.57965139
45MP0002102_abnormal_ear_morphology1.55911930
46MP0010030_abnormal_orbit_morphology1.55570177
47MP0001486_abnormal_startle_reflex1.53787275
48MP0002184_abnormal_innervation1.53341756
49MP0005394_taste/olfaction_phenotype1.52065109
50MP0005499_abnormal_olfactory_system1.52065109
51MP0000778_abnormal_nervous_system1.52032544
52MP0008789_abnormal_olfactory_epithelium1.51995855
53MP0001970_abnormal_pain_threshold1.48753248
54MP0000372_irregular_coat_pigmentation1.46998648
55MP0005551_abnormal_eye_electrophysiolog1.44356269
56MP0003195_calcinosis1.43957333
57MP0004142_abnormal_muscle_tone1.43859486
58MP0004858_abnormal_nervous_system1.43463519
59MP0002876_abnormal_thyroid_physiology1.40264506
60MP0008995_early_reproductive_senescence1.40137808
61MP0001986_abnormal_taste_sensitivity1.39128135
62MP0002234_abnormal_pharynx_morphology1.38593814
63MP0002067_abnormal_sensory_capabilities1.38174222
64MP0010094_abnormal_chromosome_stability1.34433211
65MP0005379_endocrine/exocrine_gland_phen1.33536675
66MP0005395_other_phenotype1.33117554
67MP0001905_abnormal_dopamine_level1.32798672
68MP0000631_abnormal_neuroendocrine_gland1.27787853
69MP0010386_abnormal_urinary_bladder1.27095947
70MP0008877_abnormal_DNA_methylation1.25989919
71MP0002938_white_spotting1.25308971
72MP0002638_abnormal_pupillary_reflex1.22721041
73MP0005174_abnormal_tail_pigmentation1.22582790
74MP0002909_abnormal_adrenal_gland1.17078224
75MP0002733_abnormal_thermal_nociception1.16937891
76MP0001324_abnormal_eye_pigmentation1.16826856
77MP0003693_abnormal_embryo_hatching1.16693325
78MP0006072_abnormal_retinal_apoptosis1.16216721
79MP0001485_abnormal_pinna_reflex1.15942025
80MP0002138_abnormal_hepatobiliary_system1.14089194
81MP0002161_abnormal_fertility/fecundity1.13676697
82MP0004145_abnormal_muscle_electrophysio1.13011779
83MP0003634_abnormal_glial_cell1.12600178
84MP0005085_abnormal_gallbladder_physiolo1.12213599
85MP0002233_abnormal_nose_morphology1.12192917
86MP0002822_catalepsy1.11357815
87MP0002882_abnormal_neuron_morphology1.10461506
88MP0000383_abnormal_hair_follicle1.10150675
89MP0002095_abnormal_skin_pigmentation1.10023101
90MP0003646_muscle_fatigue1.09401454
91MP0000569_abnormal_digit_pigmentation1.08269197
92MP0001502_abnormal_circadian_rhythm1.08124611
93MP0006292_abnormal_olfactory_placode1.07661598
94MP0004924_abnormal_behavior1.07184773
95MP0005386_behavior/neurological_phenoty1.07184773
96MP0002210_abnormal_sex_determination1.06802109
97MP0005075_abnormal_melanosome_morpholog1.06600638
98MP0005084_abnormal_gallbladder_morpholo1.04469576
99MP0000013_abnormal_adipose_tissue1.04371457
100MP0003937_abnormal_limbs/digits/tail_de1.02815053
101MP0004019_abnormal_vitamin_homeostasis1.02533243
102MP0002152_abnormal_brain_morphology1.02310703
103MP0004885_abnormal_endolymph1.01793006
104MP0002282_abnormal_trachea_morphology1.01407059
105MP0005195_abnormal_posterior_eye1.00441116
106MP0005389_reproductive_system_phenotype0.99837287
107MP0001765_abnormal_ion_homeostasis0.98915186
108MP0002752_abnormal_somatic_nervous0.98701071
109MP0005083_abnormal_biliary_tract0.98342716
110MP0004147_increased_porphyrin_level0.97804060
111MP0004742_abnormal_vestibular_system0.95566953
112MP0000427_abnormal_hair_cycle0.95390156
113MP0005391_vision/eye_phenotype0.90693895
114MP0000955_abnormal_spinal_cord0.90646629
115MP0005408_hypopigmentation0.89112062
116MP0006036_abnormal_mitochondrial_physio0.88244323
117MP0003633_abnormal_nervous_system0.87975551
118MP0002229_neurodegeneration0.86606651
119MP0002066_abnormal_motor_capabilities/c0.86009831
120MP0003879_abnormal_hair_cell0.85165736
121MP0000049_abnormal_middle_ear0.84643236
122MP0000026_abnormal_inner_ear0.83590346
123MP0003186_abnormal_redox_activity0.83232356
124MP0001286_abnormal_eye_development0.83010527
125MP0001963_abnormal_hearing_physiology0.82502964
126MP0003252_abnormal_bile_duct0.81244186
127MP0009697_abnormal_copulation0.80592421
128MP0003786_premature_aging0.79769324
129MP0001145_abnormal_male_reproductive0.78852664
130MP0005377_hearing/vestibular/ear_phenot0.78425210
131MP0003878_abnormal_ear_physiology0.78425210
132MP0005253_abnormal_eye_physiology0.78421194
133MP0003699_abnormal_female_reproductive0.78174519
134MP0002163_abnormal_gland_morphology0.76900942
135MP0000653_abnormal_sex_gland0.75035581
136MP0008569_lethality_at_weaning0.74893548
137MP0002928_abnormal_bile_duct0.73879941
138MP0001188_hyperpigmentation0.73580757
139MP0005409_darkened_coat_color0.73479896
140MP0004811_abnormal_neuron_physiology0.73370672
141MP0001664_abnormal_digestion0.68013346
142MP0003283_abnormal_digestive_organ0.65744386
143MP0003861_abnormal_nervous_system0.63695307
144MP0003329_amyloid_beta_deposits0.63019249
145MP0005535_abnormal_body_temperature0.62980570
146MP0008872_abnormal_physiological_respon0.62735037
147MP0002069_abnormal_eating/drinking_beha0.61751308
148MP0003121_genomic_imprinting0.60648917
149MP0003690_abnormal_glial_cell0.60566622
150MP0001943_abnormal_respiration0.59031239

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.60894988
2Abnormal respiratory motile cilium morphology (HP:0005938)9.56001026
3Abnormal respiratory epithelium morphology (HP:0012253)9.56001026
4Absent/shortened dynein arms (HP:0200106)8.25271358
5Dynein arm defect of respiratory motile cilia (HP:0012255)8.25271358
6Chronic bronchitis (HP:0004469)5.44610589
7Bronchiectasis (HP:0002110)5.37269762
8Pancreatic fibrosis (HP:0100732)4.29385968
9Medial flaring of the eyebrow (HP:0010747)3.94078601
10Gait imbalance (HP:0002141)3.71766263
11Nasal polyposis (HP:0100582)3.68911623
12Congenital primary aphakia (HP:0007707)3.65961749
13Nephronophthisis (HP:0000090)3.58099967
14Chronic sinusitis (HP:0011109)3.56228562
15Recurrent sinusitis (HP:0011108)3.55541998
16True hermaphroditism (HP:0010459)3.41695250
17Nephrogenic diabetes insipidus (HP:0009806)3.28773666
18Infertility (HP:0000789)3.27038894
19Molar tooth sign on MRI (HP:0002419)3.15541977
20Abnormality of midbrain morphology (HP:0002418)3.15541977
21Genital tract atresia (HP:0001827)3.00961588
22Median cleft lip (HP:0000161)3.00924404
23Abnormality of the nasal mucosa (HP:0000433)2.87587897
24Bronchitis (HP:0012387)2.84883881
25Abnormality of the renal medulla (HP:0100957)2.68997371
26Vaginal atresia (HP:0000148)2.65901525
27Poor coordination (HP:0002370)2.62529619
28Pancreatic cysts (HP:0001737)2.60050638
29Retinal dysplasia (HP:0007973)2.53328628
30Occipital encephalocele (HP:0002085)2.48542270
31Abnormality of the renal cortex (HP:0011035)2.43742378
32Postaxial foot polydactyly (HP:0001830)2.43432958
33Aplasia/Hypoplasia of the tongue (HP:0010295)2.42091853
34Aplasia/Hypoplasia of the lens (HP:0008063)2.37344417
35Congenital hepatic fibrosis (HP:0002612)2.37146092
36Neoplasm of head and neck (HP:0012288)2.34851104
37Esophageal neoplasm (HP:0100751)2.34851104
38Cystic liver disease (HP:0006706)2.32734010
39Postaxial hand polydactyly (HP:0001162)2.26451953
40Recurrent otitis media (HP:0000403)2.20039083
41Abnormality of the labia minora (HP:0012880)2.19634304
42Acute necrotizing encephalopathy (HP:0006965)2.18531105
43Polydipsia (HP:0001959)2.13901307
44Abnormal drinking behavior (HP:0030082)2.13901307
45Abnormality of dentin (HP:0010299)2.11753082
46Tubulointerstitial nephritis (HP:0001970)2.04210381
47Abnormal ciliary motility (HP:0012262)12.2667082
48Abnormal respiratory motile cilium physiology (HP:0012261)11.8081409
49Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.9240293
50Increased hepatocellular lipid droplets (HP:0006565)1.99108524
51Decreased circulating renin level (HP:0003351)1.95959775
52Abnormal rod and cone electroretinograms (HP:0008323)1.95682941
53Progressive macrocephaly (HP:0004481)1.93245617
54Bifid tongue (HP:0010297)1.93239717
55Preaxial hand polydactyly (HP:0001177)1.91436669
56Absent rod-and cone-mediated responses on ERG (HP:0007688)1.90957657
57Facial cleft (HP:0002006)1.87802824
58Gaze-evoked nystagmus (HP:0000640)1.86459747
59Supernumerary spleens (HP:0009799)1.85914812
60Abnormal mitochondria in muscle tissue (HP:0008316)1.83716534
61Abnormality of macular pigmentation (HP:0008002)1.83053204
62Methylmalonic acidemia (HP:0002912)1.82818768
63Oculomotor apraxia (HP:0000657)1.81040217
64Lipid accumulation in hepatocytes (HP:0006561)1.78346372
65Stage 5 chronic kidney disease (HP:0003774)1.78145186
66Congenital stationary night blindness (HP:0007642)1.77736211
67Focal motor seizures (HP:0011153)1.77698648
68Septo-optic dysplasia (HP:0100842)1.77343347
69Bile duct proliferation (HP:0001408)1.76806047
70Abnormal biliary tract physiology (HP:0012439)1.76806047
71Specific learning disability (HP:0001328)1.75633637
72Taurodontia (HP:0000679)1.75188838
73Abnormality of permanent molar morphology (HP:0011071)1.75188838
74Abnormality of the dental root (HP:0006486)1.75188838
75Renal Fanconi syndrome (HP:0001994)1.74976028
76Asplenia (HP:0001746)1.74755968
77Male pseudohermaphroditism (HP:0000037)1.74146824
78Sclerocornea (HP:0000647)1.74028643
79Decreased central vision (HP:0007663)1.73932238
80Aplasia/Hypoplasia of the spleen (HP:0010451)1.73095890
81Tubular atrophy (HP:0000092)1.71860701
82Chronic otitis media (HP:0000389)1.71502673
83Chromsome breakage (HP:0040012)1.70969840
84Anencephaly (HP:0002323)1.70783155
85Atonic seizures (HP:0010819)1.70043679
86Hyperactive renin-angiotensin system (HP:0000841)1.69234200
87Chromosomal breakage induced by crosslinking agents (HP:0003221)1.67468436
88Atelectasis (HP:0100750)1.65399992
89Abnormality of the dental pulp (HP:0006479)1.65197816
90Acute encephalopathy (HP:0006846)1.64806647
91Optic disc pallor (HP:0000543)1.64221996
92Aplasia/Hypoplasia of the uvula (HP:0010293)1.63562019
93Polyuria (HP:0000103)1.62100306
94Chronic hepatic failure (HP:0100626)1.61033322
95Type II lissencephaly (HP:0007260)1.60736401
96Myokymia (HP:0002411)1.60655279
97Increased CSF lactate (HP:0002490)1.60385468
98Abnormality of abdominal situs (HP:0011620)1.59666089
99Abdominal situs inversus (HP:0003363)1.59666089
100Metaphyseal dysplasia (HP:0100255)1.59455250
101Prominent nasal bridge (HP:0000426)1.58701323
102Abnormality of molar (HP:0011077)1.58673158
103Abnormality of molar morphology (HP:0011070)1.58673158
104Mitochondrial inheritance (HP:0001427)1.58604928
105Narrow forehead (HP:0000341)1.57878826
106Multicystic kidney dysplasia (HP:0000003)1.55017887
107Fibular hypoplasia (HP:0003038)1.53410199
108Tubulointerstitial abnormality (HP:0001969)1.53107026
109Holoprosencephaly (HP:0001360)1.51561298
110Bony spicule pigmentary retinopathy (HP:0007737)1.51503995
111Broad foot (HP:0001769)1.51104738
112Sloping forehead (HP:0000340)1.51098259
113Aplasia/Hypoplasia of the tibia (HP:0005772)1.51072394
114Short tibia (HP:0005736)1.49063863
115Retinitis pigmentosa (HP:0000510)1.48859384
116Optic nerve hypoplasia (HP:0000609)1.47505157
117Absence seizures (HP:0002121)1.47496072
118Male infertility (HP:0003251)1.47464951
119Abnormality of renal resorption (HP:0011038)1.44809134
120Dandy-Walker malformation (HP:0001305)1.44679057
121Methylmalonic aciduria (HP:0012120)1.44452478
122Intestinal atresia (HP:0011100)1.44350271
123Left ventricular hypertrophy (HP:0001712)1.44234505
124Furrowed tongue (HP:0000221)1.43432501
125Pendular nystagmus (HP:0012043)1.43092586
126Microglossia (HP:0000171)1.39922641
127Decreased testicular size (HP:0008734)1.38822391
128Asthma (HP:0002099)1.37853492
129Progressive cerebellar ataxia (HP:0002073)1.37152052
130Aganglionic megacolon (HP:0002251)1.36797250
131Hyperventilation (HP:0002883)1.36365222
132Visual hallucinations (HP:0002367)1.35074126
133Limb dystonia (HP:0002451)1.34533742
134Hypodontia (HP:0000668)1.34143991
135Ectopic anus (HP:0004397)1.30787079
136Short nail (HP:0001799)1.29410496
137Exercise intolerance (HP:0003546)1.29350559
138Widely spaced teeth (HP:0000687)1.28679954
139Focal seizures (HP:0007359)1.26208356

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK157.07584001
2PNCK4.28558757
3PDK43.84870978
4PDK33.84870978
5FRK3.69487445
6MAP2K72.76755764
7CASK2.64396108
8ARAF2.52072203
9PDK22.39135601
10MAP3K42.34671721
11ZAK2.33631991
12NUAK12.28096272
13MAP4K22.20300354
14BRSK22.18705132
15BMPR1B2.10776823
16ACVR1B2.04988696
17NTRK21.97843500
18VRK21.90150058
19TTK1.88430477
20NTRK31.79493140
21GRK71.71526299
22STK241.69245017
23TAF11.66385366
24PTK2B1.63323117
25MAP3K121.62316216
26NME11.59733546
27TAOK31.57617774
28STK38L1.47856544
29TESK11.44671986
30MARK11.44220121
31MST41.44027218
32CCNB11.40964005
33CDC71.39519294
34GRK51.39125034
35PLK31.35978129
36PLK41.34502542
37WNK41.32755670
38INSRR1.31945826
39STK391.23597619
40STK161.23559481
41MAP2K41.23187130
42PRKCG1.20829540
43MAP3K91.18453211
44NEK21.17858791
45ADRBK21.16226135
46DAPK21.15708030
47MAPKAPK31.14920368
48MKNK21.14633116
49CAMK2B1.13036961
50MINK11.11794050
51MAPK131.09713720
52MUSK1.09537296
53PHKG11.08717820
54PHKG21.08717820
55TLK11.07266318
56BRAF1.05760332
57BMPR21.05604225
58WNK31.05514644
59CAMK2A1.04987655
60PLK11.04269317
61IRAK11.04030805
62NEK61.03944742
63PAK31.00368839
64CAMK2D0.99968528
65EPHA40.98238845
66PLK20.97643185
67GRK10.96949280
68PBK0.95706881
69PRKCI0.93037438
70PRKD30.92868215
71STK30.92863750
72EIF2AK30.90584789
73AKT30.88663439
74CDK30.86587697
75CAMK2G0.84577579
76MYLK0.81212614
77VRK10.77413170
78OXSR10.76898719
79NLK0.74951687
80MAPKAPK50.74816659
81ADRBK10.74280476
82FGR0.74261533
83SIK20.73654184
84CHEK20.71968407
85TGFBR10.70450109
86DYRK30.70167432
87TRIM280.68998206
88EPHB20.67295473
89CDK50.66291854
90ERBB30.65708590
91MKNK10.64107750
92PRKCE0.63052892
93LMTK20.62676359
94ATR0.61044892
95NTRK10.60412724
96FER0.60396608
97AURKA0.59027206
98RIPK40.58744562
99PRKACA0.58338974
100ROCK20.58069865
101DAPK10.56794209
102FGFR20.55246752
103CDK90.51321431
104PRKG10.50579727
105CAMKK20.50326956
106CAMK1G0.49402448
107BRSK10.48575343
108BCR0.48117468
109GSK3A0.47731454
110PRKCQ0.47108501
111RPS6KA20.46946082
112CSNK1G10.46710728
113DYRK20.46500721
114ATM0.46076015
115TSSK60.45239317
116PASK0.43392811
117UHMK10.43337878
118AURKB0.42979943
119CSNK1G20.42657000
120DYRK1A0.41276642
121SRPK10.39570990
122PRKACG0.38690435
123CAMK10.38429490
124SIK30.37793541
125CDK190.37690459
126PIM20.37429038
127CSNK1G30.36774084
128SGK4940.36297968
129SGK2230.36297968
130CDC42BPA0.36288316
131MAPK100.36253388
132WNK10.34999415
133TNIK0.34056886
134FES0.33818176
135HIPK20.33225903
136EIF2AK10.32441471
137PRKCA0.31159573
138CDK140.30463381
139BUB10.30147549
140MELK0.29785520
141CSNK1E0.28989045
142PKN10.28090203
143PINK10.27633161
144CAMK1D0.27150976
145PRKAA20.26756878
146MAPK120.26482676
147CSNK1D0.26120159
148CHEK10.26011274
149SGK10.25572151
150CDK180.24742486
151TNK20.23748652
152PAK20.23631429
153WEE10.23223057
154SGK20.22768958

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.98361535
2Olfactory transduction_Homo sapiens_hsa047403.96129799
3Huntingtons disease_Homo sapiens_hsa050163.62034215
4Parkinsons disease_Homo sapiens_hsa050123.17795170
5Homologous recombination_Homo sapiens_hsa034403.12084403
6Alzheimers disease_Homo sapiens_hsa050102.68100664
7Nicotine addiction_Homo sapiens_hsa050332.60115063
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.52854764
9Collecting duct acid secretion_Homo sapiens_hsa049662.40893201
10Taste transduction_Homo sapiens_hsa047422.38477247
11RNA polymerase_Homo sapiens_hsa030202.36116493
12Fanconi anemia pathway_Homo sapiens_hsa034602.31715887
13Ribosome_Homo sapiens_hsa030102.30499445
14Insulin secretion_Homo sapiens_hsa049112.23346322
15Mismatch repair_Homo sapiens_hsa034302.21091294
16Cardiac muscle contraction_Homo sapiens_hsa042602.16819481
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.15810065
18Amphetamine addiction_Homo sapiens_hsa050312.05447857
19Chemical carcinogenesis_Homo sapiens_hsa052042.04314690
20Synaptic vesicle cycle_Homo sapiens_hsa047212.03434230
21Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.00702298
22Caffeine metabolism_Homo sapiens_hsa002321.99400060
23GABAergic synapse_Homo sapiens_hsa047271.97010244
24Protein export_Homo sapiens_hsa030601.88464492
25Circadian entrainment_Homo sapiens_hsa047131.84568998
26Nucleotide excision repair_Homo sapiens_hsa034201.84221069
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.84160236
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.78197075
29Glutamatergic synapse_Homo sapiens_hsa047241.77303526
30Phototransduction_Homo sapiens_hsa047441.75745591
31Morphine addiction_Homo sapiens_hsa050321.73429274
32Vibrio cholerae infection_Homo sapiens_hsa051101.65472791
33Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.59694916
34RNA degradation_Homo sapiens_hsa030181.55862210
35Calcium signaling pathway_Homo sapiens_hsa040201.52405818
36Dopaminergic synapse_Homo sapiens_hsa047281.51243795
37Renin secretion_Homo sapiens_hsa049241.47941561
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.47070549
39One carbon pool by folate_Homo sapiens_hsa006701.44437472
40Retinol metabolism_Homo sapiens_hsa008301.42774120
41Salivary secretion_Homo sapiens_hsa049701.40595352
42Gastric acid secretion_Homo sapiens_hsa049711.38270600
43Long-term potentiation_Homo sapiens_hsa047201.37314244
44Serotonergic synapse_Homo sapiens_hsa047261.34639589
45DNA replication_Homo sapiens_hsa030301.34557811
46Cocaine addiction_Homo sapiens_hsa050301.31079303
47Nitrogen metabolism_Homo sapiens_hsa009101.24334230
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.21997571
49Non-homologous end-joining_Homo sapiens_hsa034501.19933495
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.18827224
51Base excision repair_Homo sapiens_hsa034101.17904814
52Aldosterone synthesis and secretion_Homo sapiens_hsa049251.17598822
53beta-Alanine metabolism_Homo sapiens_hsa004101.13256824
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10291136
55Sulfur metabolism_Homo sapiens_hsa009201.10098710
56Cysteine and methionine metabolism_Homo sapiens_hsa002701.09139376
57Selenocompound metabolism_Homo sapiens_hsa004501.08946598
58Cholinergic synapse_Homo sapiens_hsa047251.06960852
59RNA transport_Homo sapiens_hsa030131.05431653
60Steroid hormone biosynthesis_Homo sapiens_hsa001401.05285919
61Peroxisome_Homo sapiens_hsa041461.00883236
62Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.00877256
63Pyruvate metabolism_Homo sapiens_hsa006201.00329643
64Tyrosine metabolism_Homo sapiens_hsa003500.98669107
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98647699
66Vitamin B6 metabolism_Homo sapiens_hsa007500.97920049
67Glucagon signaling pathway_Homo sapiens_hsa049220.97393833
68Tryptophan metabolism_Homo sapiens_hsa003800.97026785
69Cell cycle_Homo sapiens_hsa041100.95812964
70Purine metabolism_Homo sapiens_hsa002300.95655798
71ABC transporters_Homo sapiens_hsa020100.93993963
72Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.92701496
73cAMP signaling pathway_Homo sapiens_hsa040240.92198226
74Thyroid hormone synthesis_Homo sapiens_hsa049180.91049774
75Ether lipid metabolism_Homo sapiens_hsa005650.91035354
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90778503
77Vascular smooth muscle contraction_Homo sapiens_hsa042700.88836710
78Maturity onset diabetes of the young_Homo sapiens_hsa049500.88771288
79Estrogen signaling pathway_Homo sapiens_hsa049150.88623665
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83049510
81Spliceosome_Homo sapiens_hsa030400.82856427
82Oxytocin signaling pathway_Homo sapiens_hsa049210.82537237
83Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.82419450
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80298284
85Butanoate metabolism_Homo sapiens_hsa006500.77206678
86Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76885473
87Pancreatic secretion_Homo sapiens_hsa049720.76496788
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74906463
89Linoleic acid metabolism_Homo sapiens_hsa005910.74427919
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.73598522
91Oocyte meiosis_Homo sapiens_hsa041140.71411739
92GnRH signaling pathway_Homo sapiens_hsa049120.70145304
93Melanogenesis_Homo sapiens_hsa049160.69827477
94Propanoate metabolism_Homo sapiens_hsa006400.68759765
95Mineral absorption_Homo sapiens_hsa049780.66578194
96Long-term depression_Homo sapiens_hsa047300.66237743
97Phenylalanine metabolism_Homo sapiens_hsa003600.65927438
98Ovarian steroidogenesis_Homo sapiens_hsa049130.65263551
99Alcoholism_Homo sapiens_hsa050340.65063741
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64437956
101Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64101806
102Fatty acid degradation_Homo sapiens_hsa000710.64067766
103SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61406898
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61062991
105Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60794546
106p53 signaling pathway_Homo sapiens_hsa041150.59945092
107Vitamin digestion and absorption_Homo sapiens_hsa049770.59004144
108Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.57611941
109Folate biosynthesis_Homo sapiens_hsa007900.57228439
110Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.56491374
111Gap junction_Homo sapiens_hsa045400.56351702
112Arachidonic acid metabolism_Homo sapiens_hsa005900.56126865
113Primary bile acid biosynthesis_Homo sapiens_hsa001200.55362296
114Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55009579
115Bile secretion_Homo sapiens_hsa049760.54894019
116Sphingolipid metabolism_Homo sapiens_hsa006000.54768273
117alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.54091509
118Rheumatoid arthritis_Homo sapiens_hsa053230.52405849
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52290138
120Metabolic pathways_Homo sapiens_hsa011000.52220341
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.52020799
122Regulation of autophagy_Homo sapiens_hsa041400.51823045
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51555812
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49615110
125Carbohydrate digestion and absorption_Homo sapiens_hsa049730.49415107
126Steroid biosynthesis_Homo sapiens_hsa001000.48181985
127Circadian rhythm_Homo sapiens_hsa047100.47809736
128Basal cell carcinoma_Homo sapiens_hsa052170.45611609
129Dorso-ventral axis formation_Homo sapiens_hsa043200.45489357
130Basal transcription factors_Homo sapiens_hsa030220.45394054
131Glycerolipid metabolism_Homo sapiens_hsa005610.44983324
132Pyrimidine metabolism_Homo sapiens_hsa002400.44126678
133Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.42552459
134Proteasome_Homo sapiens_hsa030500.41778413
135Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41700148
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40749855
137Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39906871
138Wnt signaling pathway_Homo sapiens_hsa043100.36975923
139Histidine metabolism_Homo sapiens_hsa003400.35773942
140Axon guidance_Homo sapiens_hsa043600.35753146
141Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.34156516
142Hedgehog signaling pathway_Homo sapiens_hsa043400.31883646
143Phagosome_Homo sapiens_hsa041450.31861151
144Glutathione metabolism_Homo sapiens_hsa004800.31609236
145Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30808227
146Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30643810
147Dilated cardiomyopathy_Homo sapiens_hsa054140.26120477
148Fatty acid biosynthesis_Homo sapiens_hsa000610.26009938
149Type II diabetes mellitus_Homo sapiens_hsa049300.25498624
150Prion diseases_Homo sapiens_hsa050200.25339575

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