Rank | Gene Set | Z-score |
---|---|---|
1 | binding of sperm to zona pellucida (GO:0007339) | 9.76150658 |
2 | plasma membrane fusion (GO:0045026) | 9.59217399 |
3 | cell-cell recognition (GO:0009988) | 9.45193844 |
4 | piRNA metabolic process (GO:0034587) | 9.17999733 |
5 | motile cilium assembly (GO:0044458) | 9.16388255 |
6 | reproduction (GO:0000003) | 8.98241982 |
7 | spermatid development (GO:0007286) | 8.95039037 |
8 | cilium movement (GO:0003341) | 8.54769092 |
9 | regulation of cilium movement (GO:0003352) | 8.37417266 |
10 | male meiosis (GO:0007140) | 8.18335994 |
11 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 8.12126774 |
12 | synaptonemal complex organization (GO:0070193) | 7.48215321 |
13 | single fertilization (GO:0007338) | 7.34113118 |
14 | synaptonemal complex assembly (GO:0007130) | 7.26560232 |
15 | sperm capacitation (GO:0048240) | 6.77853936 |
16 | fertilization (GO:0009566) | 6.34525945 |
17 | negative regulation of inclusion body assembly (GO:0090084) | 6.24791125 |
18 | spermatogenesis (GO:0007283) | 6.18017020 |
19 | male gamete generation (GO:0048232) | 6.15973880 |
20 | microtubule depolymerization (GO:0007019) | 5.84075784 |
21 | gamete generation (GO:0007276) | 5.77571047 |
22 | DNA methylation involved in gamete generation (GO:0043046) | 5.73743751 |
23 | male meiosis I (GO:0007141) | 5.61610561 |
24 | organic cation transport (GO:0015695) | 5.30385142 |
25 | microtubule severing (GO:0051013) | 5.28589043 |
26 | germ cell development (GO:0007281) | 5.21154841 |
27 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 5.21001182 |
28 | regulation of inclusion body assembly (GO:0090083) | 5.16816726 |
29 | ventricular system development (GO:0021591) | 5.15680434 |
30 | calcium ion-dependent exocytosis (GO:0017156) | 5.00966089 |
31 | chromosome organization involved in meiosis (GO:0070192) | 4.90039653 |
32 | meiotic nuclear division (GO:0007126) | 4.87189171 |
33 | regulation of microtubule-based movement (GO:0060632) | 4.84916217 |
34 | cell recognition (GO:0008037) | 4.66711487 |
35 | meiosis I (GO:0007127) | 4.63374691 |
36 | multicellular organismal reproductive process (GO:0048609) | 4.54700749 |
37 | meiotic cell cycle (GO:0051321) | 4.47452332 |
38 | seminiferous tubule development (GO:0072520) | 4.46782449 |
39 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.44905064 |
40 | tryptophan catabolic process (GO:0006569) | 4.22306286 |
41 | indole-containing compound catabolic process (GO:0042436) | 4.22306286 |
42 | indolalkylamine catabolic process (GO:0046218) | 4.22306286 |
43 | left/right pattern formation (GO:0060972) | 4.15018478 |
44 | protein polyglutamylation (GO:0018095) | 4.11498980 |
45 | indolalkylamine metabolic process (GO:0006586) | 4.10911137 |
46 | spermatid nucleus differentiation (GO:0007289) | 4.10236135 |
47 | response to pheromone (GO:0019236) | 4.04557017 |
48 | protein localization to cilium (GO:0061512) | 4.00045771 |
49 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.99866513 |
50 | chromosome condensation (GO:0030261) | 3.90117109 |
51 | photoreceptor cell maintenance (GO:0045494) | 3.81796444 |
52 | glycerol ether metabolic process (GO:0006662) | 3.76446488 |
53 | regulation of meiosis I (GO:0060631) | 3.75405497 |
54 | tryptophan metabolic process (GO:0006568) | 3.74775181 |
55 | DNA packaging (GO:0006323) | 3.72887799 |
56 | neural tube formation (GO:0001841) | 3.68435960 |
57 | kynurenine metabolic process (GO:0070189) | 3.66991291 |
58 | cellular ketone body metabolic process (GO:0046950) | 3.65235378 |
59 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.63617649 |
60 | detection of light stimulus involved in visual perception (GO:0050908) | 3.63617649 |
61 | establishment of protein localization to Golgi (GO:0072600) | 3.62116754 |
62 | multicellular organismal development (GO:0007275) | 3.57077729 |
63 | genitalia morphogenesis (GO:0035112) | 3.54365800 |
64 | retinal cone cell development (GO:0046549) | 3.53748394 |
65 | gene silencing by RNA (GO:0031047) | 3.52172361 |
66 | ether metabolic process (GO:0018904) | 3.46949456 |
67 | L-fucose metabolic process (GO:0042354) | 3.46175030 |
68 | L-fucose catabolic process (GO:0042355) | 3.46175030 |
69 | fucose catabolic process (GO:0019317) | 3.46175030 |
70 | single strand break repair (GO:0000012) | 3.39087857 |
71 | meiotic cell cycle process (GO:1903046) | 3.31891736 |
72 | intraciliary transport (GO:0042073) | 3.31185144 |
73 | regulation of spindle checkpoint (GO:0090231) | 3.29744890 |
74 | ketone body metabolic process (GO:1902224) | 3.25853504 |
75 | behavioral response to ethanol (GO:0048149) | 3.22935975 |
76 | behavioral response to nicotine (GO:0035095) | 3.22689360 |
77 | microtubule-based movement (GO:0007018) | 3.20767566 |
78 | mitotic sister chromatid cohesion (GO:0007064) | 3.20684184 |
79 | axoneme assembly (GO:0035082) | 3.20040774 |
80 | reflex (GO:0060004) | 3.18445519 |
81 | microtubule polymerization or depolymerization (GO:0031109) | 3.16029603 |
82 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.15218672 |
83 | cilium organization (GO:0044782) | 3.14449779 |
84 | protein K11-linked deubiquitination (GO:0035871) | 3.11800849 |
85 | negative regulation of organelle assembly (GO:1902116) | 3.10377250 |
86 | chaperone-mediated protein complex assembly (GO:0051131) | 3.04378645 |
87 | regulation of centriole replication (GO:0046599) | 3.03650646 |
88 | cilium assembly (GO:0042384) | 3.03635538 |
89 | cilium morphogenesis (GO:0060271) | 3.03008302 |
90 | polyol catabolic process (GO:0046174) | 2.99923128 |
91 | carnitine transport (GO:0015879) | 2.98961606 |
92 | amino-acid betaine transport (GO:0015838) | 2.98961606 |
93 | centriole assembly (GO:0098534) | 2.96036268 |
94 | nonmotile primary cilium assembly (GO:0035058) | 2.95565501 |
95 | negative regulation of mast cell activation (GO:0033004) | 2.95105630 |
96 | indole-containing compound metabolic process (GO:0042430) | 2.93410859 |
97 | nucleus organization (GO:0006997) | 2.90995874 |
98 | protein targeting to Golgi (GO:0000042) | 2.90209567 |
99 | centriole replication (GO:0007099) | 2.90167160 |
100 | left/right axis specification (GO:0070986) | 2.88047229 |
101 | carnitine transmembrane transport (GO:1902603) | 2.87988353 |
102 | lactate metabolic process (GO:0006089) | 2.87444418 |
103 | protein refolding (GO:0042026) | 2.86714111 |
104 | regulation of sarcomere organization (GO:0060297) | 2.86441950 |
105 | cellular component assembly involved in morphogenesis (GO:0010927) | 2.85250305 |
106 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.81467454 |
107 | cellular biogenic amine catabolic process (GO:0042402) | 2.77558641 |
108 | amine catabolic process (GO:0009310) | 2.77558641 |
109 | alditol metabolic process (GO:0019400) | 2.74491192 |
110 | glycolytic process (GO:0006096) | 2.72700758 |
111 | auditory receptor cell stereocilium organization (GO:0060088) | 2.71743109 |
112 | regulation of cilium assembly (GO:1902017) | 2.71215455 |
113 | sexual reproduction (GO:0019953) | 2.70743023 |
114 | benzene-containing compound metabolic process (GO:0042537) | 2.69929344 |
115 | limb development (GO:0060173) | 2.68132275 |
116 | appendage development (GO:0048736) | 2.68132275 |
117 | sequestering of actin monomers (GO:0042989) | 2.67830076 |
118 | synapsis (GO:0007129) | 2.67424582 |
119 | thyroid hormone metabolic process (GO:0042403) | 2.66810336 |
120 | regulation of acrosome reaction (GO:0060046) | 2.66717422 |
121 | one-carbon compound transport (GO:0019755) | 2.66417124 |
122 | regulation of collateral sprouting (GO:0048670) | 2.65054677 |
123 | inner ear receptor stereocilium organization (GO:0060122) | 2.64780101 |
124 | gene silencing (GO:0016458) | 2.64471389 |
125 | peptidyl-glutamic acid modification (GO:0018200) | 2.64395483 |
126 | RNA localization (GO:0006403) | 2.64151181 |
127 | gamma-aminobutyric acid transport (GO:0015812) | 2.63850036 |
128 | microtubule bundle formation (GO:0001578) | 2.63805267 |
129 | regulation of action potential (GO:0098900) | 2.62545088 |
130 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.61032598 |
131 | smoothened signaling pathway (GO:0007224) | 2.59234798 |
132 | regulation of establishment of cell polarity (GO:2000114) | 2.56463946 |
133 | photoreceptor cell development (GO:0042461) | 2.56164964 |
134 | RNA destabilization (GO:0050779) | 2.55689814 |
135 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.55537696 |
136 | sister chromatid cohesion (GO:0007062) | 2.55337807 |
137 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.53350025 |
138 | dopamine transport (GO:0015872) | 2.51605183 |
139 | cell projection assembly (GO:0030031) | 2.51505298 |
140 | regulation of hexokinase activity (GO:1903299) | 2.51499211 |
141 | regulation of glucokinase activity (GO:0033131) | 2.51499211 |
142 | sex differentiation (GO:0007548) | 2.49481912 |
143 | neuronal action potential (GO:0019228) | 2.49275140 |
144 | startle response (GO:0001964) | 2.48995779 |
145 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 2.48573650 |
146 | signal peptide processing (GO:0006465) | 2.47582546 |
147 | regulation of hippo signaling (GO:0035330) | 2.46281634 |
148 | DNA double-strand break processing (GO:0000729) | 2.45881645 |
149 | protein localization to Golgi apparatus (GO:0034067) | 2.45369407 |
150 | central nervous system neuron axonogenesis (GO:0021955) | 2.44860238 |
151 | presynaptic membrane assembly (GO:0097105) | 2.40706917 |
152 | proline transport (GO:0015824) | 2.38586084 |
153 | primary amino compound metabolic process (GO:1901160) | 2.37754077 |
154 | reciprocal meiotic recombination (GO:0007131) | 2.36782649 |
155 | reciprocal DNA recombination (GO:0035825) | 2.36782649 |
156 | fusion of sperm to egg plasma membrane (GO:0007342) | 12.5263615 |
157 | sperm motility (GO:0030317) | 12.2329220 |
158 | cilium or flagellum-dependent cell motility (GO:0001539) | 11.5591789 |
159 | multicellular organism reproduction (GO:0032504) | 10.7752739 |
160 | cell wall macromolecule metabolic process (GO:0044036) | 10.7140820 |
161 | cell wall macromolecule catabolic process (GO:0016998) | 10.7140820 |
162 | sperm-egg recognition (GO:0035036) | 10.6036146 |
163 | acrosome reaction (GO:0007340) | 10.4843234 |
164 | axonemal dynein complex assembly (GO:0070286) | 10.2131256 |
165 | epithelial cilium movement (GO:0003351) | 10.0612678 |
166 | acrosome assembly (GO:0001675) | 10.0408879 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 8.82994397 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.24258399 |
3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.50996478 |
4 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.60388571 |
5 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.09686767 |
6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.68851064 |
7 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.59371566 |
8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.53487647 |
9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.30670438 |
10 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.30277376 |
11 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 2.26605231 |
12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26159842 |
13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.25405295 |
14 | P300_19829295_ChIP-Seq_ESCs_Human | 2.22064529 |
15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.18913837 |
16 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.08796002 |
17 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 2.08102707 |
18 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 2.05710213 |
19 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.04804096 |
20 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.99903915 |
21 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.98204604 |
22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.95627899 |
23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.93792188 |
24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.92928499 |
25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.92147216 |
26 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.91507545 |
27 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.87932900 |
28 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.86955126 |
29 | STAT3_23295773_ChIP-Seq_U87_Human | 1.83189781 |
30 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.80510272 |
31 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.80485591 |
32 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.76961515 |
33 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.76849699 |
34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.76661131 |
35 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.75733043 |
36 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.72443828 |
37 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.72012976 |
38 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.71789754 |
39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.68775130 |
40 | AR_25329375_ChIP-Seq_VCAP_Human | 1.66395229 |
41 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.63560790 |
42 | * STAT1_17558387_ChIP-Seq_HELA_Human | 1.62782623 |
43 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.55479376 |
44 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.55463772 |
45 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.53737256 |
46 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.53412537 |
47 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.50360363 |
48 | KDM2B_26808549_Chip-Seq_REH_Human | 1.49571549 |
49 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.46895796 |
50 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.44522460 |
51 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.44203153 |
52 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.43117626 |
53 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.42524737 |
54 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42360034 |
55 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.41201760 |
56 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.40877141 |
57 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40380485 |
58 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.40380485 |
59 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.39880294 |
60 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.39129043 |
61 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.38713700 |
62 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.35954844 |
63 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.35852719 |
64 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.34983887 |
65 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.34983887 |
66 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.34321574 |
67 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.34194208 |
68 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.34028076 |
69 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.33636708 |
70 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.30430705 |
71 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.28426314 |
72 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.28110847 |
73 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.27775120 |
74 | GATA3_21867929_ChIP-Seq_CD8_Mouse | 1.27770435 |
75 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.26915699 |
76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.26849913 |
77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.26849913 |
78 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.26478497 |
79 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.25845872 |
80 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.24915254 |
81 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24534712 |
82 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.24421525 |
83 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.24356698 |
84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.23665250 |
85 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 1.23227599 |
86 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.22833345 |
87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.22577277 |
88 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.19741560 |
89 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.18096125 |
90 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.16464796 |
91 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.15842764 |
92 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.15044761 |
93 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.13882283 |
94 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13372909 |
95 | TP53_16413492_ChIP-PET_HCT116_Human | 1.13334892 |
96 | GF1_26923725_Chip-Seq_HPCs_Mouse | 1.13297452 |
97 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.13288089 |
98 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.13063830 |
99 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 1.12103607 |
100 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.11701069 |
101 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.11604805 |
102 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.11514746 |
103 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.11499161 |
104 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.11019520 |
105 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.11019520 |
106 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.10461128 |
107 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.09961996 |
108 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.09764120 |
109 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.08240591 |
110 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.08184947 |
111 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.07923853 |
112 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.07822283 |
113 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.07244219 |
114 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.07056046 |
115 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05743866 |
116 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.05377569 |
117 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.04578750 |
118 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.03077486 |
119 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02965877 |
120 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02479205 |
121 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02087471 |
122 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.02006432 |
123 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.01813215 |
124 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.00764050 |
125 | FUS_26573619_Chip-Seq_HEK293_Human | 1.00667669 |
126 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.00638921 |
127 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.00305667 |
128 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.99781802 |
129 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99686083 |
130 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.98900334 |
131 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.97823651 |
132 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97331847 |
133 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.96767005 |
134 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.96625093 |
135 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.96391125 |
136 | TBL1_22424771_ChIP-Seq_293T_Human | 0.96226995 |
137 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.95188313 |
138 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 0.92556278 |
139 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.92442467 |
140 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.92336055 |
141 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.92100421 |
142 | NFYB_21822215_ChIP-Seq_K562_Human | 0.91860660 |
143 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.91127353 |
144 | * SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.90997939 |
145 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90116736 |
146 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.89849510 |
147 | * TCF4_23295773_ChIP-Seq_U87_Human | 0.89537346 |
148 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.89309011 |
149 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.89246347 |
150 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.89102781 |
151 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.88485996 |
152 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.88361801 |
153 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.88288520 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003698_abnormal_male_reproductive | 5.75688795 |
2 | MP0001929_abnormal_gametogenesis | 5.47594644 |
3 | MP0008877_abnormal_DNA_methylation | 4.92214945 |
4 | MP0002653_abnormal_ependyma_morphology | 3.71077366 |
5 | MP0002210_abnormal_sex_determination | 3.63264425 |
6 | MP0002161_abnormal_fertility/fecundity | 3.32308617 |
7 | MP0003646_muscle_fatigue | 3.08556573 |
8 | MP0001145_abnormal_male_reproductive | 3.03187493 |
9 | MP0000653_abnormal_sex_gland | 2.82258002 |
10 | MP0003195_calcinosis | 2.37006165 |
11 | MP0001501_abnormal_sleep_pattern | 2.24747387 |
12 | MP0004043_abnormal_pH_regulation | 2.16996910 |
13 | MP0005410_abnormal_fertilization | 14.5343914 |
14 | MP0005670_abnormal_white_adipose | 1.96203896 |
15 | MP0009745_abnormal_behavioral_response | 1.94994491 |
16 | MP0002102_abnormal_ear_morphology | 1.90223582 |
17 | MP0006276_abnormal_autonomic_nervous | 1.83741817 |
18 | MP0002160_abnormal_reproductive_system | 1.83451180 |
19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.82461041 |
20 | MP0002876_abnormal_thyroid_physiology | 1.78950165 |
21 | MP0000427_abnormal_hair_cycle | 1.78223568 |
22 | MP0000383_abnormal_hair_follicle | 1.76865523 |
23 | MP0006072_abnormal_retinal_apoptosis | 1.64487765 |
24 | MP0000631_abnormal_neuroendocrine_gland | 1.59703128 |
25 | MP0004133_heterotaxia | 1.55585395 |
26 | MP0001485_abnormal_pinna_reflex | 1.55029816 |
27 | MP0000372_irregular_coat_pigmentation | 1.50642044 |
28 | MP0008872_abnormal_physiological_respon | 1.46493609 |
29 | MP0004233_abnormal_muscle_weight | 1.45827302 |
30 | MP0005623_abnormal_meninges_morphology | 1.45281721 |
31 | MP0005645_abnormal_hypothalamus_physiol | 1.45212984 |
32 | MP0001984_abnormal_olfaction | 1.43864638 |
33 | MP0002735_abnormal_chemical_nociception | 1.38875342 |
34 | MP0003252_abnormal_bile_duct | 1.38435105 |
35 | MP0003136_yellow_coat_color | 1.37382528 |
36 | MP0010386_abnormal_urinary_bladder | 1.33030022 |
37 | MP0002064_seizures | 1.32885986 |
38 | MP0002837_dystrophic_cardiac_calcinosis | 1.32184649 |
39 | MP0002282_abnormal_trachea_morphology | 1.29712278 |
40 | MP0008789_abnormal_olfactory_epithelium | 1.28562345 |
41 | MP0001986_abnormal_taste_sensitivity | 1.27132708 |
42 | MP0004142_abnormal_muscle_tone | 1.25422913 |
43 | MP0002938_white_spotting | 1.21892065 |
44 | MP0002557_abnormal_social/conspecific_i | 1.20597115 |
45 | MP0005310_abnormal_salivary_gland | 1.20333318 |
46 | MP0001970_abnormal_pain_threshold | 1.19737296 |
47 | MP0002638_abnormal_pupillary_reflex | 1.16997811 |
48 | MP0010094_abnormal_chromosome_stability | 1.15909898 |
49 | MP0004924_abnormal_behavior | 1.14727832 |
50 | MP0005386_behavior/neurological_phenoty | 1.14727832 |
51 | MP0004885_abnormal_endolymph | 1.10899384 |
52 | MP0009046_muscle_twitch | 1.10647844 |
53 | MP0005174_abnormal_tail_pigmentation | 1.09666812 |
54 | MP0006292_abnormal_olfactory_placode | 1.08711536 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 1.06597602 |
56 | MP0010678_abnormal_skin_adnexa | 1.05620691 |
57 | MP0008995_early_reproductive_senescence | 1.05608209 |
58 | MP0002067_abnormal_sensory_capabilities | 1.04676815 |
59 | MP0008058_abnormal_DNA_repair | 1.04436161 |
60 | MP0002733_abnormal_thermal_nociception | 1.04319339 |
61 | MP0001765_abnormal_ion_homeostasis | 1.04158576 |
62 | MP0005389_reproductive_system_phenotype | 1.02595467 |
63 | MP0005085_abnormal_gallbladder_physiolo | 0.99680137 |
64 | MP0005084_abnormal_gallbladder_morpholo | 0.97353226 |
65 | MP0001764_abnormal_homeostasis | 0.96982026 |
66 | MP0000026_abnormal_inner_ear | 0.96784014 |
67 | MP0003699_abnormal_female_reproductive | 0.96241293 |
68 | MP0000569_abnormal_digit_pigmentation | 0.96004459 |
69 | MP0005195_abnormal_posterior_eye | 0.94303360 |
70 | MP0000566_synostosis | 0.93222566 |
71 | MP0005647_abnormal_sex_gland | 0.92050740 |
72 | MP0003787_abnormal_imprinting | 0.92007352 |
73 | MP0000230_abnormal_systemic_arterial | 0.91341114 |
74 | MP0002138_abnormal_hepatobiliary_system | 0.90973087 |
75 | MP0004215_abnormal_myocardial_fiber | 0.89722559 |
76 | MP0004270_analgesia | 0.89430110 |
77 | MP0005167_abnormal_blood-brain_barrier | 0.86542623 |
78 | MP0003937_abnormal_limbs/digits/tail_de | 0.85486849 |
79 | MP0002909_abnormal_adrenal_gland | 0.84506585 |
80 | MP0001119_abnormal_female_reproductive | 0.83983391 |
81 | MP0004742_abnormal_vestibular_system | 0.82407391 |
82 | MP0003111_abnormal_nucleus_morphology | 0.81442891 |
83 | MP0002095_abnormal_skin_pigmentation | 0.81426470 |
84 | MP0005499_abnormal_olfactory_system | 0.80975341 |
85 | MP0005394_taste/olfaction_phenotype | 0.80975341 |
86 | MP0004085_abnormal_heartbeat | 0.80593235 |
87 | MP0003718_maternal_effect | 0.78630250 |
88 | MP0005451_abnormal_body_composition | 0.78312996 |
89 | MP0003329_amyloid_beta_deposits | 0.77964722 |
90 | MP0003878_abnormal_ear_physiology | 0.70889132 |
91 | MP0005377_hearing/vestibular/ear_phenot | 0.70889132 |
92 | MP0002736_abnormal_nociception_after | 0.69536737 |
93 | MP0004145_abnormal_muscle_electrophysio | 0.69424100 |
94 | MP0004859_abnormal_synaptic_plasticity | 0.62144315 |
95 | MP0002234_abnormal_pharynx_morphology | 0.61379010 |
96 | MP0003879_abnormal_hair_cell | 0.61005224 |
97 | MP0005646_abnormal_pituitary_gland | 0.58940396 |
98 | MP0003115_abnormal_respiratory_system | 0.56982107 |
99 | MP0004036_abnormal_muscle_relaxation | 0.55506786 |
100 | MP0001968_abnormal_touch/_nociception | 0.52133726 |
101 | MP0000358_abnormal_cell_content/ | 0.51503150 |
102 | MP0003786_premature_aging | 0.49712401 |
103 | MP0003861_abnormal_nervous_system | 0.49692126 |
104 | MP0003011_delayed_dark_adaptation | 0.48749289 |
105 | MP0002063_abnormal_learning/memory/cond | 0.48313771 |
106 | MP0008057_abnormal_DNA_replication | 0.48008799 |
107 | MP0003635_abnormal_synaptic_transmissio | 0.47876907 |
108 | MP0001529_abnormal_vocalization | 0.47816963 |
109 | MP0002269_muscular_atrophy | 0.47340291 |
110 | MP0005551_abnormal_eye_electrophysiolog | 0.45399407 |
111 | MP0003880_abnormal_central_pattern | 0.44499193 |
112 | MP0002572_abnormal_emotion/affect_behav | 0.43490726 |
113 | MP0005636_abnormal_mineral_homeostasis | 0.43430362 |
114 | MP0003077_abnormal_cell_cycle | 0.43221257 |
115 | MP0002152_abnormal_brain_morphology | 0.43075956 |
116 | MP0005666_abnormal_adipose_tissue | 0.40366612 |
117 | MP0004811_abnormal_neuron_physiology | 0.39725944 |
118 | MP0001730_embryonic_growth_arrest | 0.38050657 |
119 | MP0008007_abnormal_cellular_replicative | 0.37469890 |
120 | MP0002734_abnormal_mechanical_nocicepti | 0.37406995 |
121 | MP0002928_abnormal_bile_duct | 0.37371061 |
122 | MP0003950_abnormal_plasma_membrane | 0.36893818 |
123 | MP0000751_myopathy | 0.36384881 |
124 | MP0000534_abnormal_ureter_morphology | 0.35779508 |
125 | MP0005395_other_phenotype | 0.34689006 |
126 | MP0002084_abnormal_developmental_patter | 0.34643925 |
127 | MP0001324_abnormal_eye_pigmentation | 0.33541067 |
128 | MP0005423_abnormal_somatic_nervous | 0.32801919 |
129 | MP0001502_abnormal_circadian_rhythm | 0.32162940 |
130 | MP0005397_hematopoietic_system_phenotyp | 0.32001048 |
131 | MP0001545_abnormal_hematopoietic_system | 0.32001048 |
132 | MP0002971_abnormal_brown_adipose | 0.31626081 |
133 | MP0003693_abnormal_embryo_hatching | 0.31304414 |
134 | MP0000604_amyloidosis | 0.30758750 |
135 | MP0005253_abnormal_eye_physiology | 0.30521872 |
136 | MP0003631_nervous_system_phenotype | 0.29262847 |
137 | MP0001293_anophthalmia | 0.28852874 |
138 | MP0002752_abnormal_somatic_nervous | 0.28041714 |
139 | MP0002106_abnormal_muscle_physiology | 0.27646381 |
140 | MP0002085_abnormal_embryonic_tissue | 0.27400760 |
141 | MP0006036_abnormal_mitochondrial_physio | 0.27349180 |
142 | MP0001440_abnormal_grooming_behavior | 0.26768986 |
143 | MP0000955_abnormal_spinal_cord | 0.26626694 |
144 | MP0001697_abnormal_embryo_size | 0.26283900 |
145 | MP0009278_abnormal_bone_marrow | 0.25996064 |
146 | MP0002272_abnormal_nervous_system | 0.25085575 |
147 | MP0003633_abnormal_nervous_system | 0.24454110 |
148 | MP0001963_abnormal_hearing_physiology | 0.24451464 |
149 | MP0002249_abnormal_larynx_morphology | 0.24082066 |
150 | MP0009115_abnormal_fat_cell | 0.23928507 |
151 | MP0001851_eye_inflammation | 0.23668148 |
152 | MP0001486_abnormal_startle_reflex | 0.23570248 |
153 | MP0002882_abnormal_neuron_morphology | 0.23563536 |
154 | MP0002169_no_abnormal_phenotype | 0.23535920 |
155 | MP0002229_neurodegeneration | 0.23522252 |
156 | MP0002873_normal_phenotype | 0.23391614 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal respiratory motile cilium physiology (HP:0012261) | 9.25326731 |
2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 8.75769901 |
3 | Abnormal respiratory epithelium morphology (HP:0012253) | 8.75769901 |
4 | Rhinitis (HP:0012384) | 7.71961898 |
5 | Abnormal ciliary motility (HP:0012262) | 7.30328693 |
6 | Chronic bronchitis (HP:0004469) | 7.26212250 |
7 | Infertility (HP:0000789) | 6.79712079 |
8 | Nasal polyposis (HP:0100582) | 5.91734767 |
9 | Male infertility (HP:0003251) | 4.90830674 |
10 | Abnormality of the nasal mucosa (HP:0000433) | 4.79409529 |
11 | Bronchiectasis (HP:0002110) | 4.56026642 |
12 | Nephronophthisis (HP:0000090) | 4.46597456 |
13 | Bronchitis (HP:0012387) | 4.33119840 |
14 | Chronic hepatic failure (HP:0100626) | 4.15907300 |
15 | Abnormality of the renal medulla (HP:0100957) | 3.45600986 |
16 | Abnormal spermatogenesis (HP:0008669) | 3.25855621 |
17 | Hyperventilation (HP:0002883) | 3.19300306 |
18 | Recurrent otitis media (HP:0000403) | 3.18878237 |
19 | Congenital stationary night blindness (HP:0007642) | 3.18363521 |
20 | Attenuation of retinal blood vessels (HP:0007843) | 3.17542788 |
21 | Gaze-evoked nystagmus (HP:0000640) | 3.04976718 |
22 | Recurrent sinusitis (HP:0011108) | 2.96796040 |
23 | Progressive cerebellar ataxia (HP:0002073) | 2.93255346 |
24 | Tubulointerstitial nephritis (HP:0001970) | 2.83772973 |
25 | Genetic anticipation (HP:0003743) | 2.83231249 |
26 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.78910538 |
27 | Intestinal atresia (HP:0011100) | 2.76100319 |
28 | Molar tooth sign on MRI (HP:0002419) | 2.73226948 |
29 | Abnormality of midbrain morphology (HP:0002418) | 2.73226948 |
30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.69218999 |
31 | Occipital encephalocele (HP:0002085) | 2.67900030 |
32 | Medial flaring of the eyebrow (HP:0010747) | 2.63001409 |
33 | Impulsivity (HP:0100710) | 2.62551204 |
34 | Sclerocornea (HP:0000647) | 2.62423039 |
35 | Anencephaly (HP:0002323) | 2.60682368 |
36 | Absent speech (HP:0001344) | 2.57309801 |
37 | Abolished electroretinogram (ERG) (HP:0000550) | 2.56894821 |
38 | Severe visual impairment (HP:0001141) | 2.53600643 |
39 | Abnormality of macular pigmentation (HP:0008002) | 2.46975553 |
40 | Tubular atrophy (HP:0000092) | 2.44815904 |
41 | Tubulointerstitial abnormality (HP:0001969) | 2.39736318 |
42 | Recurrent bronchitis (HP:0002837) | 2.37724900 |
43 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.35079985 |
44 | Male pseudohermaphroditism (HP:0000037) | 2.34453836 |
45 | Gonadotropin excess (HP:0000837) | 2.33658508 |
46 | Azoospermia (HP:0000027) | 2.33268322 |
47 | Type II lissencephaly (HP:0007260) | 2.32176996 |
48 | Congenital sensorineural hearing impairment (HP:0008527) | 2.29170994 |
49 | Furrowed tongue (HP:0000221) | 2.28378705 |
50 | Abnormality of the lower motor neuron (HP:0002366) | 2.28026588 |
51 | Increased corneal curvature (HP:0100692) | 2.25286212 |
52 | Keratoconus (HP:0000563) | 2.25286212 |
53 | Pendular nystagmus (HP:0012043) | 2.18377799 |
54 | Febrile seizures (HP:0002373) | 2.17967689 |
55 | Renal cortical cysts (HP:0000803) | 2.17610176 |
56 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.17012515 |
57 | Focal seizures (HP:0007359) | 2.11960335 |
58 | Broad-based gait (HP:0002136) | 2.11831023 |
59 | Cholecystitis (HP:0001082) | 2.11795490 |
60 | Abnormal gallbladder physiology (HP:0012438) | 2.11795490 |
61 | Preaxial hand polydactyly (HP:0001177) | 2.07685170 |
62 | Widely spaced teeth (HP:0000687) | 2.07090848 |
63 | Postaxial foot polydactyly (HP:0001830) | 2.03491216 |
64 | Central scotoma (HP:0000603) | 2.03473394 |
65 | Retinitis pigmentosa (HP:0000510) | 2.02812295 |
66 | Decreased circulating renin level (HP:0003351) | 2.01498179 |
67 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 13.3097473 |
68 | Absent/shortened dynein arms (HP:0200106) | 12.3821014 |
69 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 12.3821014 |
70 | Fair hair (HP:0002286) | 1.98068452 |
71 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.93161800 |
72 | Polyuria (HP:0000103) | 1.92624625 |
73 | Constricted visual fields (HP:0001133) | 1.91124822 |
74 | Cerebellar dysplasia (HP:0007033) | 1.89990545 |
75 | Tubulointerstitial fibrosis (HP:0005576) | 1.89429076 |
76 | Inability to walk (HP:0002540) | 1.89267359 |
77 | Gastrointestinal atresia (HP:0002589) | 1.87565494 |
78 | Dialeptic seizures (HP:0011146) | 1.86936148 |
79 | Amyotrophic lateral sclerosis (HP:0007354) | 1.86387737 |
80 | Heterotopia (HP:0002282) | 1.84980502 |
81 | Spastic tetraparesis (HP:0001285) | 1.84260662 |
82 | Large for gestational age (HP:0001520) | 1.83170387 |
83 | Protruding tongue (HP:0010808) | 1.82259720 |
84 | Stage 5 chronic kidney disease (HP:0003774) | 1.81368555 |
85 | Congenital hepatic fibrosis (HP:0002612) | 1.80620825 |
86 | Hypoplasia of the fovea (HP:0007750) | 1.80430381 |
87 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.80430381 |
88 | Focal motor seizures (HP:0011153) | 1.75375734 |
89 | Hyperalaninemia (HP:0003348) | 1.75028094 |
90 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.75028094 |
91 | Abnormality of alanine metabolism (HP:0010916) | 1.75028094 |
92 | Microglossia (HP:0000171) | 1.74064948 |
93 | Pancreatic fibrosis (HP:0100732) | 1.72198404 |
94 | Supernumerary spleens (HP:0009799) | 1.70714312 |
95 | Oligodactyly (hands) (HP:0001180) | 1.70470956 |
96 | Astigmatism (HP:0000483) | 1.70351119 |
97 | Polydipsia (HP:0001959) | 1.70284497 |
98 | Abnormal drinking behavior (HP:0030082) | 1.70284497 |
99 | Abnormality of the fovea (HP:0000493) | 1.68050057 |
100 | Gait imbalance (HP:0002141) | 1.67798685 |
101 | Postaxial hand polydactyly (HP:0001162) | 1.67642066 |
102 | Clumsiness (HP:0002312) | 1.66843535 |
103 | Oculomotor apraxia (HP:0000657) | 1.66681161 |
104 | Abnormality of the dental root (HP:0006486) | 1.66364476 |
105 | Taurodontia (HP:0000679) | 1.66364476 |
106 | Abnormality of permanent molar morphology (HP:0011071) | 1.66364476 |
107 | Congenital primary aphakia (HP:0007707) | 1.65808050 |
108 | Small hand (HP:0200055) | 1.65526904 |
109 | Short ribs (HP:0000773) | 1.65114990 |
110 | Progressive inability to walk (HP:0002505) | 1.64700752 |
111 | Short foot (HP:0001773) | 1.64026160 |
112 | Abnormality of the renal cortex (HP:0011035) | 1.63707872 |
113 | Highly arched eyebrow (HP:0002553) | 1.63322193 |
114 | Dyschromatopsia (HP:0007641) | 1.61816626 |
115 | Abnormality of the labia minora (HP:0012880) | 1.61691660 |
116 | Choroideremia (HP:0001139) | 1.61443430 |
117 | Renal dysplasia (HP:0000110) | 1.61374680 |
118 | Abnormal biliary tract physiology (HP:0012439) | 1.60579990 |
119 | Bile duct proliferation (HP:0001408) | 1.60579990 |
120 | Abnormality of dentin (HP:0010299) | 1.56904397 |
121 | Cystic liver disease (HP:0006706) | 1.56271812 |
122 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.53515925 |
123 | Abnormality of molar morphology (HP:0011070) | 1.53404481 |
124 | Abnormality of molar (HP:0011077) | 1.53404481 |
125 | Fibular hypoplasia (HP:0003038) | 1.53382285 |
126 | Abnormality of the dental pulp (HP:0006479) | 1.50932892 |
127 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.50375643 |
128 | Bell-shaped thorax (HP:0001591) | 1.49207004 |
129 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.48775343 |
130 | Absent epiphyses (HP:0010577) | 1.48775343 |
131 | Abnormality of renal excretion (HP:0011036) | 1.45441759 |
132 | Decreased central vision (HP:0007663) | 1.42241548 |
133 | Nephrogenic diabetes insipidus (HP:0009806) | 1.42224930 |
134 | Impaired proprioception (HP:0010831) | 1.41391109 |
135 | Absent frontal sinuses (HP:0002688) | 1.41084126 |
136 | Bundle branch block (HP:0011710) | 1.40676681 |
137 | Poor coordination (HP:0002370) | 1.36149615 |
138 | Papillary thyroid carcinoma (HP:0002895) | 1.35640767 |
139 | True hermaphroditism (HP:0010459) | 1.33854882 |
140 | Short thorax (HP:0010306) | 1.33532361 |
141 | Chronic sinusitis (HP:0011109) | 1.31833892 |
142 | Neurofibrillary tangles (HP:0002185) | 1.30586845 |
143 | Deformed sella turcica (HP:0002681) | 1.29545554 |
144 | Fatigable weakness (HP:0003473) | 1.29432321 |
145 | Abnormality of the neuromuscular junction (HP:0003398) | 1.29432321 |
146 | J-shaped sella turcica (HP:0002680) | 1.28918499 |
147 | Asymmetric septal hypertrophy (HP:0001670) | 1.28916891 |
148 | Facial cleft (HP:0002006) | 1.27292195 |
149 | Genital tract atresia (HP:0001827) | 1.26406352 |
150 | Short femoral neck (HP:0100864) | 1.25527498 |
151 | Median cleft lip (HP:0000161) | 1.24455441 |
152 | Vaginal atresia (HP:0000148) | 1.23860911 |
153 | Hemiparesis (HP:0001269) | 1.23265727 |
154 | Easy fatigability (HP:0003388) | 1.21201481 |
155 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.21083969 |
156 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.20317642 |
157 | Pancreatic cysts (HP:0001737) | 1.20064434 |
158 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.16072902 |
159 | Broad distal phalanx of finger (HP:0009836) | 1.15099506 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 7.96277621 |
2 | PDK4 | 7.95373407 |
3 | PDK3 | 7.95373407 |
4 | TESK1 | 5.17257213 |
5 | PDK2 | 5.04220416 |
6 | PRKD3 | 4.99343182 |
7 | ICK | 3.66264588 |
8 | MAP4K2 | 3.50129754 |
9 | WNK3 | 2.67670009 |
10 | ADRBK2 | 2.58031512 |
11 | ACVR1B | 2.43672113 |
12 | PTK2B | 2.28523598 |
13 | INSRR | 2.26411221 |
14 | PNCK | 2.12570950 |
15 | OXSR1 | 1.95213957 |
16 | GRK1 | 1.93492716 |
17 | NUAK1 | 1.89132905 |
18 | STK38 | 1.88424701 |
19 | WNK4 | 1.87394097 |
20 | NEK2 | 1.83788009 |
21 | ZAK | 1.77311850 |
22 | STK39 | 1.71656309 |
23 | MUSK | 1.53710146 |
24 | NTRK3 | 1.50082908 |
25 | MST4 | 1.47979669 |
26 | CDK19 | 1.42109319 |
27 | TRIM28 | 1.34940549 |
28 | EEF2K | 1.33715263 |
29 | STK16 | 1.25487376 |
30 | TTK | 1.25290877 |
31 | PLK2 | 1.24104236 |
32 | TYRO3 | 1.23860864 |
33 | PLK4 | 1.20440316 |
34 | BCR | 1.20335786 |
35 | STK38L | 1.12296917 |
36 | MKNK2 | 1.11629254 |
37 | TNIK | 1.06896114 |
38 | CCNB1 | 1.04181537 |
39 | PRKCE | 1.03689325 |
40 | ERBB3 | 1.02723431 |
41 | ADRBK1 | 1.01856486 |
42 | BRAF | 0.98427297 |
43 | PDK1 | 0.97911720 |
44 | DYRK1B | 0.97724218 |
45 | STK3 | 0.95466813 |
46 | FER | 0.95402154 |
47 | MAPK15 | 0.95360106 |
48 | TXK | 0.93848894 |
49 | PAK3 | 0.89954118 |
50 | MAP3K6 | 0.89152099 |
51 | AKT3 | 0.84811197 |
52 | CHEK2 | 0.83825038 |
53 | MAP3K9 | 0.83577369 |
54 | CSNK1G2 | 0.81581530 |
55 | KSR2 | 0.81541028 |
56 | CSNK1G1 | 0.80958460 |
57 | TAOK1 | 0.80192873 |
58 | CAMKK2 | 0.79109866 |
59 | TGFBR1 | 0.79073772 |
60 | CDC7 | 0.78049669 |
61 | TNK2 | 0.78024686 |
62 | DAPK2 | 0.74111928 |
63 | ERBB4 | 0.73779988 |
64 | MAP3K7 | 0.73445480 |
65 | RIPK4 | 0.72978499 |
66 | DYRK3 | 0.72919737 |
67 | FGFR2 | 0.71869936 |
68 | PINK1 | 0.71544015 |
69 | MAP3K4 | 0.71212910 |
70 | TEC | 0.70141033 |
71 | PAK6 | 0.68497035 |
72 | CSNK1G3 | 0.66342751 |
73 | CSNK1A1L | 0.65797592 |
74 | TLK1 | 0.65175461 |
75 | LATS2 | 0.63888151 |
76 | BRSK2 | 0.62654868 |
77 | PIK3CG | 0.61973849 |
78 | LATS1 | 0.60820906 |
79 | EIF2AK3 | 0.59804925 |
80 | WNK1 | 0.57973032 |
81 | VRK1 | 0.57921108 |
82 | NTRK2 | 0.57819069 |
83 | PRKAA2 | 0.56384641 |
84 | PDPK1 | 0.51610031 |
85 | MKNK1 | 0.49694202 |
86 | MARK2 | 0.49529673 |
87 | MAPKAPK5 | 0.49339821 |
88 | BRD4 | 0.48559297 |
89 | MAPKAPK3 | 0.48268709 |
90 | PLK3 | 0.46775109 |
91 | PRKG1 | 0.46546718 |
92 | MAP2K7 | 0.46313886 |
93 | SGK2 | 0.46263717 |
94 | PIK3CA | 0.45775044 |
95 | EPHA4 | 0.44990868 |
96 | PKN1 | 0.44472708 |
97 | CHEK1 | 0.44347223 |
98 | CAMK1G | 0.43955245 |
99 | PRKACA | 0.42502649 |
100 | CHUK | 0.41754597 |
101 | CAMK1 | 0.41564495 |
102 | TIE1 | 0.41364621 |
103 | ARAF | 0.41189181 |
104 | TRPM7 | 0.40416011 |
105 | NLK | 0.39659684 |
106 | EPHA3 | 0.39652571 |
107 | PLK1 | 0.39276214 |
108 | PHKG2 | 0.39156542 |
109 | PHKG1 | 0.39156542 |
110 | PRKAA1 | 0.38868010 |
111 | FLT3 | 0.36945609 |
112 | MAP2K1 | 0.36735640 |
113 | CSNK1A1 | 0.36665951 |
114 | IRAK1 | 0.36560573 |
115 | RAF1 | 0.36191372 |
116 | OBSCN | 0.35649212 |
117 | MAP2K6 | 0.35081596 |
118 | ATM | 0.34474959 |
119 | PAK1 | 0.33597970 |
120 | PRKCA | 0.32357708 |
121 | MARK1 | 0.30188461 |
122 | ERBB2 | 0.30172951 |
123 | PASK | 0.28095674 |
124 | PRKCG | 0.26658631 |
125 | LMTK2 | 0.25964726 |
126 | CAMK2A | 0.25803109 |
127 | ATR | 0.24773335 |
128 | CDK3 | 0.24363586 |
129 | BMPR1B | 0.23586196 |
130 | MAPK13 | 0.23382326 |
131 | CDK9 | 0.23334670 |
132 | CDK15 | 0.20497158 |
133 | MAP2K4 | 0.20006096 |
134 | MOS | 0.19667823 |
135 | MTOR | 0.19422185 |
136 | CDK18 | 0.18330415 |
137 | STK11 | 0.18127158 |
138 | TESK2 | 0.18017526 |
139 | BRSK1 | 0.17387483 |
140 | CAMKK1 | 0.16719008 |
141 | BMPR2 | 0.16707214 |
142 | KSR1 | 0.15232446 |
143 | CDK11A | 0.14688662 |
144 | MAP3K5 | 0.14615577 |
145 | DYRK2 | 0.14437887 |
146 | PRKCZ | 0.13681843 |
147 | RPS6KB1 | 0.13452622 |
148 | NEK6 | 0.12695168 |
149 | PRKD2 | 0.11418112 |
150 | AURKA | 0.11089053 |
151 | WEE1 | 0.10809433 |
152 | CDK14 | 0.08750340 |
153 | CSNK1D | 0.08400538 |
154 | GSK3B | 0.08104154 |
155 | CASK | 0.07541161 |
156 | CDK1 | 0.06987637 |
157 | TAOK3 | 0.05553942 |
158 | CDK2 | 0.05232533 |
159 | MAP3K1 | 0.05170240 |
160 | MAPK10 | 0.03865079 |
161 | RPS6KA1 | 0.03063637 |
162 | MELK | 0.02289959 |
163 | PRKCQ | 0.01995118 |
164 | IRAK2 | 0.01794431 |
165 | RPS6KA3 | 0.01670604 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 4.10588461 |
2 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 3.60886860 |
3 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 3.44582614 |
4 | Pyruvate metabolism_Homo sapiens_hsa00620 | 3.11362489 |
5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.02742573 |
6 | Basal transcription factors_Homo sapiens_hsa03022 | 3.00479885 |
7 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.92305500 |
8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.88381082 |
9 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.81644325 |
10 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 2.62723453 |
11 | Phototransduction_Homo sapiens_hsa04744 | 2.55955960 |
12 | Oocyte meiosis_Homo sapiens_hsa04114 | 2.55785751 |
13 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.54786974 |
14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.29704131 |
15 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.29668018 |
16 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.22983477 |
17 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.12812791 |
18 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.08405009 |
19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.01431976 |
20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.00681065 |
21 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.99415866 |
22 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.97240704 |
23 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.96817262 |
24 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.86426561 |
25 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.83967249 |
26 | ABC transporters_Homo sapiens_hsa02010 | 1.82416858 |
27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.79627241 |
28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.71126064 |
29 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.70119357 |
30 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.68858354 |
31 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.67971762 |
32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.67307479 |
33 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.63813705 |
34 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.63672407 |
35 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.54598121 |
36 | Retinol metabolism_Homo sapiens_hsa00830 | 1.47817826 |
37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.47797931 |
38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.47247484 |
39 | Long-term potentiation_Homo sapiens_hsa04720 | 1.45791193 |
40 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.45345441 |
41 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.41727915 |
42 | Histidine metabolism_Homo sapiens_hsa00340 | 1.37386557 |
43 | Renin secretion_Homo sapiens_hsa04924 | 1.35857952 |
44 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.29938208 |
45 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.29387383 |
46 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.28782174 |
47 | Huntingtons disease_Homo sapiens_hsa05016 | 1.21417688 |
48 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.21414524 |
49 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.21316089 |
50 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.20047964 |
51 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.20043514 |
52 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.19456703 |
53 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.17756563 |
54 | Olfactory transduction_Homo sapiens_hsa04740 | 1.15857402 |
55 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.15214893 |
56 | GABAergic synapse_Homo sapiens_hsa04727 | 1.15101883 |
57 | RNA transport_Homo sapiens_hsa03013 | 1.14095767 |
58 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.14035593 |
59 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.12742360 |
60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.11457234 |
61 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.11114657 |
62 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.08480695 |
63 | RNA degradation_Homo sapiens_hsa03018 | 1.06817362 |
64 | Peroxisome_Homo sapiens_hsa04146 | 1.05070141 |
65 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.04791801 |
66 | Mineral absorption_Homo sapiens_hsa04978 | 1.04369105 |
67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.03587311 |
68 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.03261741 |
69 | Purine metabolism_Homo sapiens_hsa00230 | 1.01943138 |
70 | Cell cycle_Homo sapiens_hsa04110 | 1.01173873 |
71 | Protein export_Homo sapiens_hsa03060 | 1.01134896 |
72 | Insulin secretion_Homo sapiens_hsa04911 | 0.99636596 |
73 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.99389774 |
74 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.97776854 |
75 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.96436013 |
76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94702742 |
77 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.92535346 |
78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.91325524 |
79 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.91101229 |
80 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.88982089 |
81 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.88428186 |
82 | RNA polymerase_Homo sapiens_hsa03020 | 0.88143530 |
83 | Circadian entrainment_Homo sapiens_hsa04713 | 0.87761753 |
84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.86000698 |
85 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.85843691 |
86 | Taste transduction_Homo sapiens_hsa04742 | 0.85237437 |
87 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.84376234 |
88 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.81537441 |
89 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.80769792 |
90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.78366231 |
91 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.77935077 |
92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.75995732 |
93 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.73228778 |
94 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.71593896 |
95 | Salivary secretion_Homo sapiens_hsa04970 | 0.70318915 |
96 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.69901592 |
97 | Nicotine addiction_Homo sapiens_hsa05033 | 0.67984519 |
98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67830444 |
99 | Long-term depression_Homo sapiens_hsa04730 | 0.67730403 |
100 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66133667 |
101 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65865414 |
102 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.64100608 |
103 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.61260812 |
104 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.58801071 |
105 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57344951 |
106 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.57244799 |
107 | Lysine degradation_Homo sapiens_hsa00310 | 0.57045350 |
108 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.56851697 |
109 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56566921 |
110 | Endocytosis_Homo sapiens_hsa04144 | 0.55757178 |
111 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54583452 |
112 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.53691943 |
113 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.53501444 |
114 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.51019784 |
115 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.50965309 |
116 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.49050731 |
117 | Cocaine addiction_Homo sapiens_hsa05030 | 0.48464954 |
118 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.46755086 |
119 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45941017 |
120 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.45328023 |
121 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.45210435 |
122 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45147201 |
123 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.44586351 |
124 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.43410736 |
125 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.42452911 |
126 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.41644549 |
127 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41503149 |
128 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.36854420 |
129 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.36332147 |
130 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.35909920 |
131 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.35759196 |
132 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.33956377 |
133 | Morphine addiction_Homo sapiens_hsa05032 | 0.33497875 |
134 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.33172800 |
135 | Bile secretion_Homo sapiens_hsa04976 | 0.32444686 |
136 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31990235 |
137 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.31116674 |
138 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.28750659 |
139 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28436541 |
140 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.28405087 |
141 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.28297544 |
142 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.27305127 |
143 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.25959774 |
144 | Asthma_Homo sapiens_hsa05310 | 0.25551902 |
145 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.25049400 |
146 | Alcoholism_Homo sapiens_hsa05034 | 0.24057556 |
147 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.20824636 |
148 | Homologous recombination_Homo sapiens_hsa03440 | 0.19953196 |
149 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.18611778 |
150 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.16488884 |