EFR3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.98081482
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.80269480
3locomotory exploration behavior (GO:0035641)5.71745842
4pyrimidine nucleobase catabolic process (GO:0006208)5.43629898
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.36650841
6presynaptic membrane assembly (GO:0097105)5.27630889
7vocalization behavior (GO:0071625)5.23806005
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.16627487
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.04813379
10synaptic vesicle exocytosis (GO:0016079)5.02238975
11regulation of glutamate receptor signaling pathway (GO:1900449)4.86355125
12presynaptic membrane organization (GO:0097090)4.82324588
13regulation of synaptic vesicle exocytosis (GO:2000300)4.74456077
14glutamate secretion (GO:0014047)4.73362485
15layer formation in cerebral cortex (GO:0021819)4.60839580
16behavioral response to nicotine (GO:0035095)4.55587736
17neuron cell-cell adhesion (GO:0007158)4.52574573
18neurotransmitter secretion (GO:0007269)4.42312906
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.41799052
20nucleobase catabolic process (GO:0046113)4.40134659
21protein localization to synapse (GO:0035418)4.39306753
22dendritic spine morphogenesis (GO:0060997)4.37364121
23ionotropic glutamate receptor signaling pathway (GO:0035235)4.35766226
24neuronal action potential propagation (GO:0019227)4.35517954
25regulation of synaptic vesicle transport (GO:1902803)4.34586535
26regulation of synapse structural plasticity (GO:0051823)4.31753721
27positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.29373662
28regulation of neuronal synaptic plasticity (GO:0048168)4.28144677
29regulation of long-term neuronal synaptic plasticity (GO:0048169)4.21204665
30exploration behavior (GO:0035640)4.21024516
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.13107566
32neurotransmitter-gated ion channel clustering (GO:0072578)4.01031874
33proline transport (GO:0015824)3.95932573
34cellular potassium ion homeostasis (GO:0030007)3.95926865
35gamma-aminobutyric acid transport (GO:0015812)3.93175176
36membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.92246466
37long-term memory (GO:0007616)3.88444732
38synaptic transmission, glutamatergic (GO:0035249)3.85609342
39cerebellar Purkinje cell differentiation (GO:0021702)3.84468674
40glutamate receptor signaling pathway (GO:0007215)3.81605126
41limb bud formation (GO:0060174)3.73158986
42axonal fasciculation (GO:0007413)3.71953941
43sodium ion export (GO:0071436)3.68475898
44neuron-neuron synaptic transmission (GO:0007270)3.68077866
45neuron recognition (GO:0008038)3.67976237
46neurotransmitter transport (GO:0006836)3.67955612
47activation of protein kinase A activity (GO:0034199)3.62953002
48auditory behavior (GO:0031223)3.59228726
49positive regulation of membrane potential (GO:0045838)3.53611848
50dendrite morphogenesis (GO:0048813)3.52762570
51cell proliferation in forebrain (GO:0021846)3.51153797
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.50506797
53response to auditory stimulus (GO:0010996)3.49380930
54regulation of excitatory postsynaptic membrane potential (GO:0060079)3.48786050
55neuromuscular process controlling posture (GO:0050884)3.48298023
56positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.43104671
57neuromuscular process controlling balance (GO:0050885)3.41691891
58prepulse inhibition (GO:0060134)3.41564614
59transmission of nerve impulse (GO:0019226)3.40707320
60positive regulation of synapse maturation (GO:0090129)3.38766787
61cell communication by electrical coupling (GO:0010644)3.37306760
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.36324511
63glycine transport (GO:0015816)3.35550361
64central nervous system projection neuron axonogenesis (GO:0021952)3.35262043
65synaptic vesicle endocytosis (GO:0048488)3.35234841
66regulation of neurotransmitter levels (GO:0001505)3.32722553
67regulation of postsynaptic membrane potential (GO:0060078)3.31819406
68cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.30413218
69regulation of synaptic plasticity (GO:0048167)3.28681396
70startle response (GO:0001964)3.28009360
71negative regulation of synaptic transmission, GABAergic (GO:0032229)3.26673762
72neuronal ion channel clustering (GO:0045161)3.26633413
73retinal ganglion cell axon guidance (GO:0031290)3.26301041
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.25882778
75regulation of dendritic spine morphogenesis (GO:0061001)3.24496818
76membrane depolarization during action potential (GO:0086010)3.22736640
77positive regulation of neurotransmitter transport (GO:0051590)3.20179030
78regulation of neurotransmitter secretion (GO:0046928)3.19070541
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.18700728
80regulation of synaptic transmission, glutamatergic (GO:0051966)3.13735434
81long-term synaptic potentiation (GO:0060291)3.11384406
82cell migration in hindbrain (GO:0021535)3.10184711
83regulation of neurotransmitter transport (GO:0051588)3.09777127
84sulfation (GO:0051923)3.09515395
85membrane hyperpolarization (GO:0060081)3.08914210
86postsynaptic membrane organization (GO:0001941)3.08042833
87neuromuscular synaptic transmission (GO:0007274)3.07640292
88negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.06712853
89membrane depolarization (GO:0051899)3.05657772
90regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.05518025
91negative regulation of transcription regulatory region DNA binding (GO:2000678)3.04942599
92synapse assembly (GO:0007416)3.04868009
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.04585798
94response to pheromone (GO:0019236)3.04197267
95adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.03670772
96L-amino acid import (GO:0043092)3.02684965
97regulation of vesicle fusion (GO:0031338)3.01661054
98protein polyglutamylation (GO:0018095)2.99580833
99regulation of collateral sprouting (GO:0048670)2.98972686
100regulation of glucocorticoid secretion (GO:2000849)2.96747549
101positive regulation of dendritic spine development (GO:0060999)2.96055781
102cerebellar granule cell differentiation (GO:0021707)2.95093246
103positive regulation of synaptic transmission (GO:0050806)2.94939053
104positive regulation of potassium ion transmembrane transport (GO:1901381)2.94605729
105cerebellar Purkinje cell layer development (GO:0021680)2.93330046
106G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.92449147
107spinal cord development (GO:0021510)2.92116387
108learning (GO:0007612)2.91275561
109adult walking behavior (GO:0007628)2.91099897
110establishment of nucleus localization (GO:0040023)2.89410584
111dendritic spine organization (GO:0097061)2.89365879
112mechanosensory behavior (GO:0007638)2.87300196
113dopamine receptor signaling pathway (GO:0007212)2.87294050
114regulation of synaptic transmission (GO:0050804)2.87291732
115synapse organization (GO:0050808)2.86284502
116neuromuscular process (GO:0050905)2.86037710
117negative regulation of axon guidance (GO:1902668)2.85822295
118otic vesicle formation (GO:0030916)2.84208795
119positive regulation of synapse assembly (GO:0051965)2.82168059
120central nervous system neuron axonogenesis (GO:0021955)2.80389687
121somite development (GO:0061053)2.74970716
122establishment of mitochondrion localization (GO:0051654)2.73916410
123negative regulation of axon extension (GO:0030517)2.72608839
124fear response (GO:0042596)2.65186281
125glycosphingolipid biosynthetic process (GO:0006688)2.62715297
126serotonin metabolic process (GO:0042428)2.60293581
127neuronal action potential (GO:0019228)2.59294757
128negative regulation of astrocyte differentiation (GO:0048712)2.58786549
129multicellular organismal signaling (GO:0035637)2.55698871
130cerebral cortex radially oriented cell migration (GO:0021799)2.55530196
131behavioral fear response (GO:0001662)2.55023421
132behavioral defense response (GO:0002209)2.55023421
133negative regulation of axon extension involved in axon guidance (GO:0048843)2.53794226
134positive regulation of dendritic spine morphogenesis (GO:0061003)2.53792938
135hippocampus development (GO:0021766)2.53785669
136negative chemotaxis (GO:0050919)2.49611706
137regulation of axon guidance (GO:1902667)2.47720161
138regulation of neurotransmitter uptake (GO:0051580)2.47303932
139olfactory bulb development (GO:0021772)2.44469009
140negative regulation of response to food (GO:0032096)2.44239589
141negative regulation of appetite (GO:0032099)2.44239589
142regulation of timing of cell differentiation (GO:0048505)2.43440638
143regulation of synapse assembly (GO:0051963)2.42892776
144water-soluble vitamin biosynthetic process (GO:0042364)2.42841514
145regulation of dendritic spine development (GO:0060998)2.42436050
146negative regulation of dendrite development (GO:2000171)2.42227709
147C4-dicarboxylate transport (GO:0015740)2.40455249

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.24509582
2GBX2_23144817_ChIP-Seq_PC3_Human3.23666277
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.05775491
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.93798578
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92405949
6REST_21632747_ChIP-Seq_MESCs_Mouse2.73512181
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.68448035
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.68448035
9DROSHA_22980978_ChIP-Seq_HELA_Human2.57457544
10RARB_27405468_Chip-Seq_BRAIN_Mouse2.55409866
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.52975839
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.49550213
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.49149824
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.48215935
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.45858488
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44985110
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.41447054
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.27308898
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.26080723
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.24542391
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23701027
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.21463352
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.19432725
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.12393922
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.12185962
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.07105080
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04205610
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.02160781
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.00189833
30FUS_26573619_Chip-Seq_HEK293_Human1.99185067
31EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.93488430
32HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.89844652
33POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84955443
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.78355115
35AR_21572438_ChIP-Seq_LNCaP_Human1.76475683
36EWS_26573619_Chip-Seq_HEK293_Human1.65613735
37CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62492041
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.60090200
39SMAD4_21799915_ChIP-Seq_A2780_Human1.53221579
40VDR_22108803_ChIP-Seq_LS180_Human1.52246823
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.50728545
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.49518988
43ZNF274_21170338_ChIP-Seq_K562_Hela1.49011614
44POU5F1_16153702_ChIP-ChIP_HESCs_Human1.43826708
45TAF15_26573619_Chip-Seq_HEK293_Human1.43249468
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42871197
47MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39468688
48* RING1B_27294783_Chip-Seq_ESCs_Mouse1.36278163
49UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.35116824
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34067253
51IGF1R_20145208_ChIP-Seq_DFB_Human1.32089958
52* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.31438649
53SOX2_21211035_ChIP-Seq_LN229_Gbm1.30413499
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.29875695
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.28963892
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28073539
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27913716
58RBPJ_22232070_ChIP-Seq_NCS_Mouse1.27800990
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27687048
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27687048
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.25760694
62AR_19668381_ChIP-Seq_PC3_Human1.24747140
63ZFP57_27257070_Chip-Seq_ESCs_Mouse1.24456816
64P300_19829295_ChIP-Seq_ESCs_Human1.23502135
65* CBP_20019798_ChIP-Seq_JUKART_Human1.23336392
66* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23336392
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21856103
68MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21536745
69STAT3_23295773_ChIP-Seq_U87_Human1.21036422
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.20034663
71DNAJC2_21179169_ChIP-ChIP_NT2_Human1.17965019
72* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17385080
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.16554666
74BMI1_23680149_ChIP-Seq_NPCS_Mouse1.16052304
75* AR_25329375_ChIP-Seq_VCAP_Human1.15724376
76IRF1_19129219_ChIP-ChIP_H3396_Human1.15647172
77SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14748949
78FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.14681448
79KDM2B_26808549_Chip-Seq_K562_Human1.14407815
80OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14298227
81BCAT_22108803_ChIP-Seq_LS180_Human1.13689365
82ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13224630
83RNF2_27304074_Chip-Seq_NSC_Mouse1.12438323
84SOX9_26525672_Chip-Seq_HEART_Mouse1.10427452
85HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09872046
86TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09569956
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09420034
88TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.09128248
89SMAD_19615063_ChIP-ChIP_OVARY_Human1.08941299
90ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08726148
91P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08464467
92CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07050274
93WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06479927
94TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05990825
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.05919105
96EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05633397
97TCF4_23295773_ChIP-Seq_U87_Human1.05517354
98PIAS1_25552417_ChIP-Seq_VCAP_Human1.04903601
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04832072
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04377369
101NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04354917
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04289934
103KDM2B_26808549_Chip-Seq_REH_Human1.04080150
104RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03182772
105YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03083815
106SMAD4_21741376_ChIP-Seq_HESCs_Human1.02405736
107BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02154942
108RUNX2_22187159_ChIP-Seq_PCA_Human1.01807406
109* ARNT_22903824_ChIP-Seq_MCF-7_Human1.01119771
110TAL1_26923725_Chip-Seq_HPCs_Mouse1.00995162
111CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00968227
112JUN_21703547_ChIP-Seq_K562_Human1.00650280
113* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00392386
114* AHR_22903824_ChIP-Seq_MCF-7_Human0.99292778
115SMAD3_21741376_ChIP-Seq_ESCs_Human0.99167455
116FLI1_21867929_ChIP-Seq_TH2_Mouse0.97900121
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96439009
118STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.96297630
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.96086441
120AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92844263
121GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92724518
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.91904860
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.91122801
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91105049
125RXR_22108803_ChIP-Seq_LS180_Human0.90854885
126TET1_21490601_ChIP-Seq_MESCs_Mouse0.87251411
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86392051
128OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.86256694
129ER_23166858_ChIP-Seq_MCF-7_Human0.85702168
130TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84438237
131GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83912342
132SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.83791016
133TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83779408
134* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.83488033
135PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.82340697

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.05038654
2MP0003880_abnormal_central_pattern4.33037641
3MP0003635_abnormal_synaptic_transmissio3.98852007
4MP0004270_analgesia3.51107043
5MP0001968_abnormal_touch/_nociception3.43035418
6MP0009745_abnormal_behavioral_response3.35088469
7MP0002063_abnormal_learning/memory/cond3.23342034
8MP0009046_muscle_twitch3.18236635
9MP0005423_abnormal_somatic_nervous3.10864170
10MP0002064_seizures3.03034747
11MP0006292_abnormal_olfactory_placode2.82378362
12MP0002572_abnormal_emotion/affect_behav2.76197502
13MP0001486_abnormal_startle_reflex2.62100496
14MP0002822_catalepsy2.61896452
15MP0002734_abnormal_mechanical_nocicepti2.61237986
16MP0002272_abnormal_nervous_system2.45659068
17MP0003122_maternal_imprinting2.44461742
18MP0002735_abnormal_chemical_nociception2.17737204
19MP0001440_abnormal_grooming_behavior2.11650379
20MP0002102_abnormal_ear_morphology2.09440316
21MP0002733_abnormal_thermal_nociception2.08850084
22MP0001501_abnormal_sleep_pattern2.06845923
23MP0002557_abnormal_social/conspecific_i2.04961228
24MP0001984_abnormal_olfaction2.04543099
25MP0002067_abnormal_sensory_capabilities2.03262147
26MP0002736_abnormal_nociception_after1.96926672
27MP0004924_abnormal_behavior1.96299157
28MP0005386_behavior/neurological_phenoty1.96299157
29MP0008569_lethality_at_weaning1.96003556
30MP0001970_abnormal_pain_threshold1.93393809
31MP0006276_abnormal_autonomic_nervous1.90196543
32MP0000778_abnormal_nervous_system1.89901572
33MP0005646_abnormal_pituitary_gland1.86710411
34MP0002909_abnormal_adrenal_gland1.86049711
35MP0002184_abnormal_innervation1.84270521
36MP0004811_abnormal_neuron_physiology1.79565105
37MP0005645_abnormal_hypothalamus_physiol1.74811232
38MP0003787_abnormal_imprinting1.63907773
39MP0009780_abnormal_chondrocyte_physiolo1.62132398
40MP0008789_abnormal_olfactory_epithelium1.60701629
41MP0001529_abnormal_vocalization1.55669119
42MP0000569_abnormal_digit_pigmentation1.55169963
43MP0000049_abnormal_middle_ear1.55077179
44MP0004885_abnormal_endolymph1.52609251
45MP0000955_abnormal_spinal_cord1.51985688
46MP0004858_abnormal_nervous_system1.48523633
47MP0003329_amyloid_beta_deposits1.47237484
48MP0001905_abnormal_dopamine_level1.45916707
49MP0003136_yellow_coat_color1.45819077
50MP0002882_abnormal_neuron_morphology1.42949133
51MP0008877_abnormal_DNA_methylation1.41574447
52MP0002066_abnormal_motor_capabilities/c1.41365984
53MP0004133_heterotaxia1.35192723
54MP0002751_abnormal_autonomic_nervous1.32176148
55MP0001502_abnormal_circadian_rhythm1.30165196
56MP0003633_abnormal_nervous_system1.29465388
57MP0004142_abnormal_muscle_tone1.25658710
58MP0005253_abnormal_eye_physiology1.22669118
59MP0003938_abnormal_ear_development1.22617262
60MP0003879_abnormal_hair_cell1.22334392
61MP0000026_abnormal_inner_ear1.18503893
62MP0000751_myopathy1.18127703
63MP0006072_abnormal_retinal_apoptosis1.17550055
64MP0008961_abnormal_basal_metabolism1.17391703
65MP0002152_abnormal_brain_morphology1.14864150
66MP0002938_white_spotting1.14511213
67MP0003690_abnormal_glial_cell1.14273384
68MP0004145_abnormal_muscle_electrophysio1.12742924
69MP0003121_genomic_imprinting1.12156436
70MP0003631_nervous_system_phenotype1.10585038
71MP0003119_abnormal_digestive_system1.03675111
72MP0002234_abnormal_pharynx_morphology1.01136493
73MP0002069_abnormal_eating/drinking_beha1.00090157
74MP0003937_abnormal_limbs/digits/tail_de0.99004313
75MP0004134_abnormal_chest_morphology0.97696508
76MP0003137_abnormal_impulse_conducting0.97193518
77MP0004085_abnormal_heartbeat0.96831481
78MP0005499_abnormal_olfactory_system0.95782100
79MP0005394_taste/olfaction_phenotype0.95782100
80MP0005195_abnormal_posterior_eye0.94918051
81MP0002229_neurodegeneration0.91808684
82MP0002160_abnormal_reproductive_system0.90495152
83MP0001293_anophthalmia0.90152614
84MP0001177_atelectasis0.89821126
85MP0004742_abnormal_vestibular_system0.89163782
86MP0001188_hyperpigmentation0.89086181
87MP0003283_abnormal_digestive_organ0.88940844
88MP0005171_absent_coat_pigmentation0.88311772
89MP0003755_abnormal_palate_morphology0.88132041
90MP0002638_abnormal_pupillary_reflex0.86704789
91MP0003890_abnormal_embryonic-extraembry0.86579408
92MP0003634_abnormal_glial_cell0.86564843
93MP0000920_abnormal_myelination0.86190259
94MP0008872_abnormal_physiological_respon0.86100451
95MP0005551_abnormal_eye_electrophysiolog0.85202564
96MP0003123_paternal_imprinting0.82956710
97MP0003632_abnormal_nervous_system0.82721200
98MP0009250_abnormal_appendicular_skeleto0.82282154
99MP0002233_abnormal_nose_morphology0.82070518
100MP0000631_abnormal_neuroendocrine_gland0.81396623
101MP0010386_abnormal_urinary_bladder0.79966469
102MP0002752_abnormal_somatic_nervous0.78099062
103MP0004215_abnormal_myocardial_fiber0.77360872
104MP0008874_decreased_physiological_sensi0.76449835
105MP0002249_abnormal_larynx_morphology0.76238668
106MP0002837_dystrophic_cardiac_calcinosis0.76205453
107MP0001299_abnormal_eye_distance/0.75728635
108MP0000534_abnormal_ureter_morphology0.75327240
109MP0005535_abnormal_body_temperature0.74768817
110MP0001963_abnormal_hearing_physiology0.72495224
111MP0003942_abnormal_urinary_system0.72403820
112MP0005167_abnormal_blood-brain_barrier0.72252196
113MP0002653_abnormal_ependyma_morphology0.71636683
114MP0005448_abnormal_energy_balance0.70894700
115MP0005391_vision/eye_phenotype0.69721303
116MP0001986_abnormal_taste_sensitivity0.69404381
117MP0003172_abnormal_lysosome_physiology0.68708179
118MP0000013_abnormal_adipose_tissue0.68618475
119MP0003075_altered_response_to0.66455710
120MP0003861_abnormal_nervous_system0.63702975
121MP0001485_abnormal_pinna_reflex0.60585836
122MP0005409_darkened_coat_color0.57189912
123MP0005623_abnormal_meninges_morphology0.56940448
124MP0005187_abnormal_penis_morphology0.56710577
125MP0010769_abnormal_survival0.56153424
126MP0001943_abnormal_respiration0.56041575
127MP0010770_preweaning_lethality0.54923925
128MP0002082_postnatal_lethality0.54923925
129MP0000639_abnormal_adrenal_gland0.53155382
130MP0000604_amyloidosis0.52601038
131MP0010768_mortality/aging0.52423694

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.65784123
2Myokymia (HP:0002411)6.45713826
3Focal seizures (HP:0007359)5.43497687
4Visual hallucinations (HP:0002367)4.51626108
5Progressive cerebellar ataxia (HP:0002073)4.50973037
6Epileptic encephalopathy (HP:0200134)4.39454643
7Action tremor (HP:0002345)4.32342448
8Atonic seizures (HP:0010819)4.09872766
9Febrile seizures (HP:0002373)4.07715519
10Absence seizures (HP:0002121)3.93305288
11Papilledema (HP:0001085)3.83678361
12Ankle clonus (HP:0011448)3.75265282
13Supranuclear gaze palsy (HP:0000605)3.74057717
14Generalized tonic-clonic seizures (HP:0002069)3.61197103
15Broad-based gait (HP:0002136)3.55267850
16Dialeptic seizures (HP:0011146)3.51364285
17Truncal ataxia (HP:0002078)3.47854087
18True hermaphroditism (HP:0010459)3.35969378
19Pendular nystagmus (HP:0012043)3.31719487
20Poor eye contact (HP:0000817)3.28439519
21Abnormal eating behavior (HP:0100738)3.26805739
22Agitation (HP:0000713)3.24661246
23Pancreatic fibrosis (HP:0100732)3.23675265
24Depression (HP:0000716)3.22993487
25Impaired vibration sensation in the lower limbs (HP:0002166)3.16746461
26Gaze-evoked nystagmus (HP:0000640)3.16556191
27Pancreatic cysts (HP:0001737)3.12165044
28Dysdiadochokinesis (HP:0002075)3.10402764
29Urinary bladder sphincter dysfunction (HP:0002839)3.09911140
30Mutism (HP:0002300)3.08810997
31Dysmetria (HP:0001310)3.00461470
32Anxiety (HP:0000739)2.97563390
33Impaired social interactions (HP:0000735)2.95990400
34Abnormal social behavior (HP:0012433)2.95990400
35Postural instability (HP:0002172)2.95262146
36Genetic anticipation (HP:0003743)2.94816257
37Urinary urgency (HP:0000012)2.76529113
38Hemiplegia (HP:0002301)2.76052383
39Spastic gait (HP:0002064)2.73460645
40Nephronophthisis (HP:0000090)2.72076962
41Hemiparesis (HP:0001269)2.71624246
42Drooling (HP:0002307)2.67724427
43Excessive salivation (HP:0003781)2.67724427
44Septo-optic dysplasia (HP:0100842)2.67649358
45Abnormality of the corticospinal tract (HP:0002492)2.66173124
46Torticollis (HP:0000473)2.64387399
47Intention tremor (HP:0002080)2.63751876
48Progressive inability to walk (HP:0002505)2.62977167
49Impaired smooth pursuit (HP:0007772)2.58506729
50Polyphagia (HP:0002591)2.57350750
51Optic nerve hypoplasia (HP:0000609)2.55479660
52Scanning speech (HP:0002168)2.53021699
53Limb dystonia (HP:0002451)2.51579581
54Pheochromocytoma (HP:0002666)2.51080789
55Abnormality of midbrain morphology (HP:0002418)2.49910311
56Molar tooth sign on MRI (HP:0002419)2.49910311
57Lissencephaly (HP:0001339)2.48282342
58Abnormality of the labia minora (HP:0012880)2.48217183
59Termporal pattern (HP:0011008)2.47851029
60Insidious onset (HP:0003587)2.47851029
61Hyperventilation (HP:0002883)2.46690739
62Gait imbalance (HP:0002141)2.44270870
63Hypoglycemic seizures (HP:0002173)2.44231686
64Ventricular fibrillation (HP:0001663)2.41749167
65Lower limb muscle weakness (HP:0007340)2.38391616
66Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.37795212
67Amblyopia (HP:0000646)2.37694868
68Diplopia (HP:0000651)2.36336061
69Abnormality of binocular vision (HP:0011514)2.36336061
70Megalencephaly (HP:0001355)2.35982341
71Abnormal EKG (HP:0003115)2.35690868
72Focal dystonia (HP:0004373)2.33530016
73Abnormality of ocular smooth pursuit (HP:0000617)2.33341203
74Medial flaring of the eyebrow (HP:0010747)2.32148916
75Abnormality of the lower motor neuron (HP:0002366)2.30507489
76Stereotypic behavior (HP:0000733)2.30122893
77Retinal dysplasia (HP:0007973)2.29826007
78Genital tract atresia (HP:0001827)2.29776243
79Failure to thrive in infancy (HP:0001531)2.28999995
80Dysmetric saccades (HP:0000641)2.27248566
81Vaginal atresia (HP:0000148)2.26940260
82Neurofibrillary tangles (HP:0002185)2.22448773
83Hypoplastic pelvis (HP:0008839)2.22316484
84Bradykinesia (HP:0002067)2.21563699
85Keratoconus (HP:0000563)2.19973527
86Increased corneal curvature (HP:0100692)2.19973527
87Sleep apnea (HP:0010535)2.19111319
88Epileptiform EEG discharges (HP:0011182)2.16914311
89Abolished electroretinogram (ERG) (HP:0000550)2.15880479
90Cystic liver disease (HP:0006706)2.15734557
91EEG with generalized epileptiform discharges (HP:0011198)2.15093161
92Sclerocornea (HP:0000647)2.13453668
93Absent speech (HP:0001344)2.13232687
94Craniofacial dystonia (HP:0012179)2.12285569
95Pointed chin (HP:0000307)2.12239869
96Insomnia (HP:0100785)2.10979652
97Obstructive sleep apnea (HP:0002870)2.10836043
98Pachygyria (HP:0001302)2.09820067
99Short 4th metacarpal (HP:0010044)2.09811571
100Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.09811571
101Clonus (HP:0002169)2.09255488
102Prolonged QT interval (HP:0001657)2.08949606
103Methylmalonic acidemia (HP:0002912)2.07026799
104Hypsarrhythmia (HP:0002521)2.06431146
105Status epilepticus (HP:0002133)2.05497007
106Chronic hepatic failure (HP:0100626)2.04892112
107Abnormality of the renal medulla (HP:0100957)2.04692232
108Decreased central vision (HP:0007663)2.04508326
109Type II lissencephaly (HP:0007260)2.04325367
110Neuroendocrine neoplasm (HP:0100634)2.04323996
111Congenital primary aphakia (HP:0007707)2.04050170
112Fetal akinesia sequence (HP:0001989)2.03013549
113Impaired vibratory sensation (HP:0002495)2.01785567
114Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.01588141
115Nephrogenic diabetes insipidus (HP:0009806)2.01153827
116Aplasia/Hypoplasia of the tongue (HP:0010295)1.99485109
117Cerebral inclusion bodies (HP:0100314)1.98442622
118Inability to walk (HP:0002540)1.95789998
119Anencephaly (HP:0002323)1.94270345
120Congenital stationary night blindness (HP:0007642)1.93217013
121Annular pancreas (HP:0001734)1.92736992
122Blue irides (HP:0000635)1.92327398
123Incomplete penetrance (HP:0003829)1.91655507
124Aqueductal stenosis (HP:0002410)1.91564950
125Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89594135
126Postural tremor (HP:0002174)1.88050398
127Abnormality of saccadic eye movements (HP:0000570)1.87794887
128Specific learning disability (HP:0001328)1.87731910
129Aplasia involving bones of the extremities (HP:0009825)1.87690576
130Aplasia involving bones of the upper limbs (HP:0009823)1.87690576
131Aplasia of the phalanges of the hand (HP:0009802)1.87690576
132Psychosis (HP:0000709)1.87486042
133Gait ataxia (HP:0002066)1.86175254
134Aplasia/Hypoplasia of the tibia (HP:0005772)1.85648506
135Postaxial hand polydactyly (HP:0001162)1.84812557
136Macroorchidism (HP:0000053)1.84395330
137Neuronal loss in central nervous system (HP:0002529)1.83932383
138Confusion (HP:0001289)1.83216134
139Small hand (HP:0200055)1.82785204
140Bundle branch block (HP:0011710)1.81582397
141Neoplasm of the heart (HP:0100544)1.81272470
142Abnormality of salivation (HP:0100755)1.81149093
143Cutaneous finger syndactyly (HP:0010554)1.77988505
144Short tibia (HP:0005736)1.76713332
145Tented upper lip vermilion (HP:0010804)1.75707529
146Intellectual disability, moderate (HP:0002342)1.75158679
147Absent septum pellucidum (HP:0001331)1.73635233
148Intestinal atresia (HP:0011100)1.70659521
149Thyroid-stimulating hormone excess (HP:0002925)1.70257470
150Renal hypoplasia (HP:0000089)1.68872920
151Oligodactyly (hands) (HP:0001180)1.68658347
152Humeroradial synostosis (HP:0003041)1.68101527
153Synostosis involving the elbow (HP:0003938)1.68101527
154Postaxial foot polydactyly (HP:0001830)1.68007894
155Hypoplasia of the brainstem (HP:0002365)1.66946552
156Aplasia/Hypoplasia of the brainstem (HP:0007362)1.66946552
157Methylmalonic aciduria (HP:0012120)1.65591269
158Morphological abnormality of the inner ear (HP:0011390)1.65316527
159Aplasia/Hypoplasia of the sternum (HP:0006714)1.63791145
160Furrowed tongue (HP:0000221)1.63670443
161Chorioretinal atrophy (HP:0000533)1.63120371

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.40524684
2MAP3K93.70952757
3MARK13.65210720
4EPHA43.44007149
5MAP3K43.10169376
6MINK12.78827232
7NTRK22.67598458
8MAP4K22.53170590
9MAP2K72.49434871
10FRK2.35388445
11PAK62.31759729
12DAPK22.07045281
13PRKD31.93597004
14BMPR1B1.93433325
15MAP2K41.92502973
16TNIK1.90141556
17CAMKK11.89326190
18DYRK21.83825115
19KSR11.77399886
20MAP3K121.75806871
21KSR21.65228800
22GRK11.60284374
23TRIM281.59172699
24CDK51.56509525
25ADRBK21.56275616
26NTRK11.54059819
27UHMK11.53887371
28MAPK131.53793548
29SIK21.50897103
30CASK1.49347345
31STK381.48932009
32CDK191.48380596
33TYRO31.38829196
34PHKG11.36811969
35PHKG21.36811969
36EPHB21.27400377
37SIK31.26221414
38CSNK1G31.25484710
39INSRR1.18638339
40PRKCG1.16823517
41CSNK1A1L1.16544870
42CSNK1G11.16459774
43PNCK1.15909755
44AKT31.09609162
45WNK31.08834693
46FES1.08195883
47PRPF4B1.07473631
48SGK2231.02282579
49SGK4941.02282579
50CAMKK21.01327449
51PLK21.00490387
52GRK50.99226625
53DAPK10.97305061
54RIPK40.97045519
55CAMK10.96282169
56PRKCH0.95744408
57CDK180.94831902
58PAK30.94823600
59NUAK10.94744391
60LATS20.93747410
61RIPK10.92971368
62FGFR20.92404041
63MKNK20.91401577
64CAMK2A0.90688962
65TAOK10.89099364
66CDK150.88137482
67BCR0.87771445
68STK110.87664611
69LMTK20.85875237
70CDK140.85331521
71RET0.84991114
72PKN10.84733995
73CAMK1G0.82013181
74MAP3K20.81619801
75CSNK1G20.80709073
76OXSR10.80396435
77ARAF0.79486759
78ALK0.78178486
79MARK20.78088496
80SGK20.77241836
81PINK10.76798111
82CDK11A0.76165692
83EPHA30.74759153
84ZAK0.73918346
85DYRK1A0.71135305
86SGK30.69951317
87CAMK2B0.69769868
88STK38L0.69678707
89SGK10.67998927
90CDC42BPA0.67643502
91WNK40.67473817
92WNK10.66378295
93ACVR1B0.65517754
94STK390.63119686
95MAP3K130.61897713
96PRKCZ0.59750725
97VRK10.59495850
98PRKCE0.58332868
99CSNK1A10.57937252
100TLK10.56628709
101CAMK40.54161678
102PDPK10.54158840
103TNK20.53874800
104NEK60.53268218
105PDK10.53209943
106CSNK1D0.52251257
107RPS6KA30.52195524
108SRPK10.50972702
109MAPK100.50588380
110ERBB30.50258299
111PLK30.49958966
112MKNK10.46816550
113FYN0.46805895
114PRKACA0.45933601
115CAMK2D0.45636379
116CDK30.44852570
117CDC70.44172202
118PRKD20.43672254
119FER0.43662842
120CAMK2G0.42837250
121DYRK30.42806640
122ADRBK10.41506334
123DMPK0.41494801
124RAF10.41316305
125STK160.40687605
126MAP3K10.40594681
127CCNB10.38636978
128MAPK150.38064293
129MAP3K60.37021637
130CSNK1E0.35748566
131OBSCN0.35518357
132PRKCB0.35083142
133PDGFRA0.34461156
134MAP2K60.34151972
135PTK2B0.34071451
136TIE10.32299404
137DDR20.31711423
138PRKG10.31688618
139ROCK10.31275877
140ERBB20.31226182
141ROCK20.31047021
142PRKDC0.30848087
143PRKACB0.30837427

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.82299647
2Synaptic vesicle cycle_Homo sapiens_hsa047213.11355977
3GABAergic synapse_Homo sapiens_hsa047272.96948569
4Olfactory transduction_Homo sapiens_hsa047402.81695791
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.68021373
6Morphine addiction_Homo sapiens_hsa050322.65334861
7Circadian entrainment_Homo sapiens_hsa047132.62608381
8Glutamatergic synapse_Homo sapiens_hsa047242.53897435
9Long-term potentiation_Homo sapiens_hsa047202.26196119
10Amphetamine addiction_Homo sapiens_hsa050312.18994341
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.17576726
12Dopaminergic synapse_Homo sapiens_hsa047282.16043977
13Insulin secretion_Homo sapiens_hsa049112.04576818
14Salivary secretion_Homo sapiens_hsa049702.00150557
15Cholinergic synapse_Homo sapiens_hsa047251.89696819
16Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.85605474
17Gastric acid secretion_Homo sapiens_hsa049711.80219652
18Cocaine addiction_Homo sapiens_hsa050301.76748853
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.74694746
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.73166235
21Oxidative phosphorylation_Homo sapiens_hsa001901.73077992
22Taste transduction_Homo sapiens_hsa047421.72916236
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.70846026
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.59701254
25Serotonergic synapse_Homo sapiens_hsa047261.59551110
26Long-term depression_Homo sapiens_hsa047301.59079662
27Oxytocin signaling pathway_Homo sapiens_hsa049211.52969298
28Renin secretion_Homo sapiens_hsa049241.52733516
29Parkinsons disease_Homo sapiens_hsa050121.49577243
30Calcium signaling pathway_Homo sapiens_hsa040201.41778522
31Hedgehog signaling pathway_Homo sapiens_hsa043401.40750577
32Gap junction_Homo sapiens_hsa045401.37627125
33Type II diabetes mellitus_Homo sapiens_hsa049301.37169667
34GnRH signaling pathway_Homo sapiens_hsa049121.37004901
35Basal cell carcinoma_Homo sapiens_hsa052171.30424178
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.28172436
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.27893698
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.27773364
39cAMP signaling pathway_Homo sapiens_hsa040241.26522301
40Axon guidance_Homo sapiens_hsa043601.26152796
41Steroid biosynthesis_Homo sapiens_hsa001001.24804780
42Nitrogen metabolism_Homo sapiens_hsa009101.24770920
43Alzheimers disease_Homo sapiens_hsa050101.17224391
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.16925848
45Melanogenesis_Homo sapiens_hsa049161.16793988
46Estrogen signaling pathway_Homo sapiens_hsa049151.16293945
47Protein export_Homo sapiens_hsa030601.14430989
48Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13281856
49Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.10176838
50Collecting duct acid secretion_Homo sapiens_hsa049661.09676820
51ErbB signaling pathway_Homo sapiens_hsa040121.08842914
52Maturity onset diabetes of the young_Homo sapiens_hsa049501.07633883
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07240180
54Fanconi anemia pathway_Homo sapiens_hsa034601.06051388
55Huntingtons disease_Homo sapiens_hsa050161.02243492
56Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00864838
57Glioma_Homo sapiens_hsa052141.00723784
58Dorso-ventral axis formation_Homo sapiens_hsa043201.00080510
59cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97662092
60Cardiac muscle contraction_Homo sapiens_hsa042600.97623308
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90896791
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.89789883
63Basal transcription factors_Homo sapiens_hsa030220.89037643
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88975806
65Hippo signaling pathway_Homo sapiens_hsa043900.87375063
66Dilated cardiomyopathy_Homo sapiens_hsa054140.86183074
67Oocyte meiosis_Homo sapiens_hsa041140.82960966
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.81578096
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.81388871
70Tryptophan metabolism_Homo sapiens_hsa003800.81077329
71Pancreatic secretion_Homo sapiens_hsa049720.80330516
72Thyroid hormone synthesis_Homo sapiens_hsa049180.79300915
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79254272
74Vibrio cholerae infection_Homo sapiens_hsa051100.78091070
75Choline metabolism in cancer_Homo sapiens_hsa052310.75535357
76MAPK signaling pathway_Homo sapiens_hsa040100.73891359
77Phototransduction_Homo sapiens_hsa047440.73654835
78beta-Alanine metabolism_Homo sapiens_hsa004100.70684529
79Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.70229529
80Homologous recombination_Homo sapiens_hsa034400.70161856
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.69907734
82Type I diabetes mellitus_Homo sapiens_hsa049400.67019145
83Linoleic acid metabolism_Homo sapiens_hsa005910.66814734
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66389765
85Selenocompound metabolism_Homo sapiens_hsa004500.64406800
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63973444
87Ras signaling pathway_Homo sapiens_hsa040140.63804932
88Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62524347
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62308699
90Ether lipid metabolism_Homo sapiens_hsa005650.61946362
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61295531
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60734517
93Melanoma_Homo sapiens_hsa052180.60521736
94alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59035986
95Alcoholism_Homo sapiens_hsa050340.58523263
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58511853
97Propanoate metabolism_Homo sapiens_hsa006400.58304676
98Bile secretion_Homo sapiens_hsa049760.57713387
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57572396
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.57414484
101Renal cell carcinoma_Homo sapiens_hsa052110.57166646
102VEGF signaling pathway_Homo sapiens_hsa043700.54927766
103Rap1 signaling pathway_Homo sapiens_hsa040150.54680718
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53632674
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52903538
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52793713
107Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52013549
108Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50253511
109RNA degradation_Homo sapiens_hsa030180.49905562
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49833020
111Endocytosis_Homo sapiens_hsa041440.49394713
112Endometrial cancer_Homo sapiens_hsa052130.49183231
113Vitamin B6 metabolism_Homo sapiens_hsa007500.48490097
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48322696
115Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48236352
116Glucagon signaling pathway_Homo sapiens_hsa049220.47711512
117Inositol phosphate metabolism_Homo sapiens_hsa005620.47608663
118Regulation of autophagy_Homo sapiens_hsa041400.47201115
119Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46580165
120Circadian rhythm_Homo sapiens_hsa047100.46341862
121Wnt signaling pathway_Homo sapiens_hsa043100.45434427
122mTOR signaling pathway_Homo sapiens_hsa041500.44768145
123Insulin signaling pathway_Homo sapiens_hsa049100.44543616
124Ovarian steroidogenesis_Homo sapiens_hsa049130.43606017
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43469062
126Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42793097
127Prion diseases_Homo sapiens_hsa050200.42456697
128Peroxisome_Homo sapiens_hsa041460.40754804
129Chemical carcinogenesis_Homo sapiens_hsa052040.40369012
130Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40225747
131Glycerolipid metabolism_Homo sapiens_hsa005610.39505588
132RNA polymerase_Homo sapiens_hsa030200.38923531
133Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37376959
134Non-small cell lung cancer_Homo sapiens_hsa052230.36587647
135Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35895012
136Chemokine signaling pathway_Homo sapiens_hsa040620.35128236
137Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.33456178
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.32674194
139Butanoate metabolism_Homo sapiens_hsa006500.30888116
140Colorectal cancer_Homo sapiens_hsa052100.30370050
141Adipocytokine signaling pathway_Homo sapiens_hsa049200.29063772
142SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26229323

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