Rank | Gene Set | Z-score |
---|---|---|
1 | sarcomere organization (GO:0045214) | 7.41554424 |
2 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 7.27069977 |
3 | cardiac myofibril assembly (GO:0055003) | 7.11123455 |
4 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 6.47564706 |
5 | myofibril assembly (GO:0030239) | 6.38060169 |
6 | actin-myosin filament sliding (GO:0033275) | 5.96548242 |
7 | muscle filament sliding (GO:0030049) | 5.96548242 |
8 | tricarboxylic acid cycle (GO:0006099) | 5.92626913 |
9 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.87630379 |
10 | plasma membrane repair (GO:0001778) | 5.74926127 |
11 | cardiac muscle contraction (GO:0060048) | 5.48606731 |
12 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 5.40308184 |
13 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 5.32491042 |
14 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.30991171 |
15 | cardiac muscle cell development (GO:0055013) | 5.13762350 |
16 | regulation of skeletal muscle contraction (GO:0014819) | 5.12812095 |
17 | carnitine shuttle (GO:0006853) | 5.09828545 |
18 | regulation of actin filament-based movement (GO:1903115) | 5.04884427 |
19 | actin-mediated cell contraction (GO:0070252) | 4.93154251 |
20 | actomyosin structure organization (GO:0031032) | 4.85607329 |
21 | cardiac cell development (GO:0055006) | 4.81831837 |
22 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.79970511 |
23 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.76291117 |
24 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.75647483 |
25 | ventricular cardiac muscle cell action potential (GO:0086005) | 4.66610567 |
26 | regulation of relaxation of muscle (GO:1901077) | 4.62522222 |
27 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.62287775 |
28 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.60438134 |
29 | creatine metabolic process (GO:0006600) | 4.58341822 |
30 | regulation of cofactor metabolic process (GO:0051193) | 4.51328095 |
31 | regulation of coenzyme metabolic process (GO:0051196) | 4.51328095 |
32 | fatty acid transmembrane transport (GO:1902001) | 4.49314964 |
33 | striated muscle contraction (GO:0006941) | 4.45119546 |
34 | adult heart development (GO:0007512) | 4.42719315 |
35 | cardiac muscle hypertrophy (GO:0003300) | 4.42688436 |
36 | striated muscle hypertrophy (GO:0014897) | 4.25099428 |
37 | regulation of cell communication by electrical coupling (GO:0010649) | 4.20575819 |
38 | regulation of sequestering of triglyceride (GO:0010889) | 4.14787626 |
39 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.14680214 |
40 | * cardiac muscle tissue morphogenesis (GO:0055008) | 4.08703461 |
41 | * heart trabecula formation (GO:0060347) | 4.08054157 |
42 | regulation of membrane repolarization (GO:0060306) | 4.06742078 |
43 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.05642686 |
44 | regulation of cardioblast differentiation (GO:0051890) | 4.03544580 |
45 | regulation of sarcomere organization (GO:0060297) | 3.99919459 |
46 | cell communication involved in cardiac conduction (GO:0086065) | 3.95234300 |
47 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.93511657 |
48 | actin filament-based movement (GO:0030048) | 3.92400107 |
49 | regulation of striated muscle contraction (GO:0006942) | 3.91888357 |
50 | NADH metabolic process (GO:0006734) | 3.91053404 |
51 | regulation of the force of heart contraction (GO:0002026) | 3.80210729 |
52 | carnitine transmembrane transport (GO:1902603) | 3.76812326 |
53 | 2-oxoglutarate metabolic process (GO:0006103) | 3.74619171 |
54 | negative regulation of potassium ion transport (GO:0043267) | 3.73983602 |
55 | regulation of fatty acid oxidation (GO:0046320) | 3.70778505 |
56 | * muscle tissue morphogenesis (GO:0060415) | 3.70209827 |
57 | muscle hypertrophy (GO:0014896) | 3.65553442 |
58 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.63243602 |
59 | regulation of sulfur metabolic process (GO:0042762) | 3.61079159 |
60 | cell communication by electrical coupling (GO:0010644) | 3.56335832 |
61 | detection of molecule of bacterial origin (GO:0032490) | 3.51990857 |
62 | cardiac muscle adaptation (GO:0014887) | 3.51253526 |
63 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.51253526 |
64 | muscle hypertrophy in response to stress (GO:0003299) | 3.51253526 |
65 | amino-acid betaine transport (GO:0015838) | 3.49419906 |
66 | carnitine transport (GO:0015879) | 3.49419906 |
67 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.48622556 |
68 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.45897076 |
69 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.41232744 |
70 | macroautophagy (GO:0016236) | 3.34141112 |
71 | relaxation of cardiac muscle (GO:0055119) | 3.29862488 |
72 | heart process (GO:0003015) | 3.28549421 |
73 | heart contraction (GO:0060047) | 3.28549421 |
74 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.28522558 |
75 | cardiac muscle cell action potential (GO:0086001) | 3.21549593 |
76 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.21499361 |
77 | fatty acid beta-oxidation (GO:0006635) | 3.19651141 |
78 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 3.19532556 |
79 | regulation of cardiac muscle contraction (GO:0055117) | 3.17545141 |
80 | cellular response to epinephrine stimulus (GO:0071872) | 3.17216165 |
81 | negative regulation of protein localization to cell surface (GO:2000009) | 3.16623632 |
82 | muscle contraction (GO:0006936) | 3.16219905 |
83 | striated muscle cell development (GO:0055002) | 3.12345807 |
84 | skeletal muscle contraction (GO:0003009) | 3.11954335 |
85 | regulation of heart rate (GO:0002027) | 3.10412899 |
86 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.09575585 |
87 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.09575585 |
88 | striated muscle adaptation (GO:0014888) | 3.05652244 |
89 | respiratory electron transport chain (GO:0022904) | 3.04343033 |
90 | succinate metabolic process (GO:0006105) | 3.03076936 |
91 | positive regulation of cation channel activity (GO:2001259) | 3.02222917 |
92 | glucan catabolic process (GO:0009251) | 3.01517409 |
93 | skeletal muscle adaptation (GO:0043501) | 3.00117158 |
94 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.97479224 |
95 | tricarboxylic acid metabolic process (GO:0072350) | 2.97069660 |
96 | cardiac conduction (GO:0061337) | 2.96814264 |
97 | aspartate family amino acid catabolic process (GO:0009068) | 2.96715456 |
98 | toxin transport (GO:1901998) | 2.96509660 |
99 | regulation of heart contraction (GO:0008016) | 2.95739478 |
100 | oxidative phosphorylation (GO:0006119) | 2.95738952 |
101 | ATP synthesis coupled proton transport (GO:0015986) | 2.94762716 |
102 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.94762716 |
103 | muscle system process (GO:0003012) | 2.93572880 |
104 | electron transport chain (GO:0022900) | 2.93039065 |
105 | ventricular cardiac muscle cell development (GO:0055015) | 2.92903756 |
106 | regulation of ATP catabolic process (GO:1903289) | 2.92858088 |
107 | regulation of ATPase activity (GO:0043462) | 2.92858088 |
108 | response to epinephrine (GO:0071871) | 2.92771771 |
109 | cellular polysaccharide catabolic process (GO:0044247) | 2.85478008 |
110 | response to mercury ion (GO:0046689) | 2.82015252 |
111 | glycogen catabolic process (GO:0005980) | 2.81089196 |
112 | negative regulation of necroptotic process (GO:0060546) | 2.80322941 |
113 | positive regulation of myotube differentiation (GO:0010831) | 2.78867717 |
114 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.77519706 |
115 | quaternary ammonium group transport (GO:0015697) | 2.73356991 |
116 | positive regulation by symbiont of host defense response (GO:0052509) | 2.69358307 |
117 | modulation by symbiont of host defense response (GO:0052031) | 2.69358307 |
118 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.69358307 |
119 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.69358307 |
120 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.69358307 |
121 | modulation by symbiont of host immune response (GO:0052553) | 2.69358307 |
122 | regulation of necroptotic process (GO:0060544) | 2.65539693 |
123 | response to muscle activity (GO:0014850) | 2.63788194 |
124 | detection of external biotic stimulus (GO:0098581) | 2.63568611 |
125 | polysaccharide catabolic process (GO:0000272) | 2.52838833 |
126 | macrophage activation involved in immune response (GO:0002281) | 2.51381650 |
127 | response to inactivity (GO:0014854) | 2.50369306 |
128 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.48633277 |
129 | cellular response to fluid shear stress (GO:0071498) | 2.48563915 |
130 | import into cell (GO:0098657) | 2.47502308 |
131 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.44992804 |
132 | negative regulation of cell killing (GO:0031342) | 2.44992804 |
133 | response to laminar fluid shear stress (GO:0034616) | 2.43881986 |
134 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.41334474 |
135 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.39706765 |
136 | relaxation of muscle (GO:0090075) | 2.39436411 |
137 | cellular response to catecholamine stimulus (GO:0071870) | 2.39412577 |
138 | cellular response to monoamine stimulus (GO:0071868) | 2.39412577 |
139 | positive regulation of myoblast differentiation (GO:0045663) | 2.38396433 |
140 | detection of other organism (GO:0098543) | 2.35807060 |
141 | fructose metabolic process (GO:0006000) | 2.35738699 |
142 | macrophage activation (GO:0042116) | 2.33512849 |
143 | glucan metabolic process (GO:0044042) | 2.32115514 |
144 | cellular glucan metabolic process (GO:0006073) | 2.32115514 |
145 | positive regulation of receptor recycling (GO:0001921) | 2.29249873 |
146 | detection of biotic stimulus (GO:0009595) | 2.28959499 |
147 | peptidyl-threonine phosphorylation (GO:0018107) | 2.24873861 |
148 | glycogen metabolic process (GO:0005977) | 2.24706875 |
149 | peptidyl-threonine modification (GO:0018210) | 2.22145188 |
150 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.21914361 |
151 | negative regulation of necrotic cell death (GO:0060547) | 2.21550506 |
152 | negative regulation of complement activation (GO:0045916) | 2.20785896 |
153 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.20344210 |
154 | hypotonic response (GO:0006971) | 2.19063228 |
155 | skeletal muscle fiber development (GO:0048741) | 2.18956868 |
156 | response to monoamine (GO:0071867) | 2.17212706 |
157 | response to catecholamine (GO:0071869) | 2.17212706 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 6.30455391 |
2 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 3.60392283 |
3 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 3.27176220 |
4 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.27139636 |
5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.21671609 |
6 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 3.17805060 |
7 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 3.11324295 |
8 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 3.11324295 |
9 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.88387877 |
10 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.63950247 |
11 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.41867350 |
12 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.28728239 |
13 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.25138856 |
14 | GATA1_22025678_ChIP-Seq_K562_Human | 2.23864359 |
15 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.21600852 |
16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.09628822 |
17 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07906311 |
18 | * MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.95247794 |
19 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.93980518 |
20 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.92808803 |
21 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.92419733 |
22 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.80548157 |
23 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.77443342 |
24 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.75395017 |
25 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.72629956 |
26 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.67847055 |
27 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.66354953 |
28 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.66035146 |
29 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.65017018 |
30 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.64280198 |
31 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.62388759 |
32 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.60971846 |
33 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.60443331 |
34 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.57215699 |
35 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.55356041 |
36 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.53251525 |
37 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.52356580 |
38 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.52261327 |
39 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.50615459 |
40 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.49976073 |
41 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.48868534 |
42 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.46791879 |
43 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.45986686 |
44 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.44148989 |
45 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.42836714 |
46 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.41960191 |
47 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.41317453 |
48 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.40333543 |
49 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.39043788 |
50 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.38243235 |
51 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.38109565 |
52 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.37952511 |
53 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.34292928 |
54 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.33866143 |
55 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.33607939 |
56 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.33549419 |
57 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.30818378 |
58 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.30107895 |
59 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.28066492 |
60 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.26884976 |
61 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.25869868 |
62 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.25869868 |
63 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.25602988 |
64 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.22825211 |
65 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.22317790 |
66 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.22267220 |
67 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.22248807 |
68 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.22217200 |
69 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.21648727 |
70 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.21312432 |
71 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.19500778 |
72 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.18341232 |
73 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.17583418 |
74 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17527269 |
75 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.16905592 |
76 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.16872756 |
77 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.16019235 |
78 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.15132614 |
79 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.14618884 |
80 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.14618247 |
81 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.14569570 |
82 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14346321 |
83 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.13651956 |
84 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.11743046 |
85 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.11267915 |
86 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09308313 |
87 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.08831300 |
88 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.07758336 |
89 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.07758336 |
90 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.07165847 |
91 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.06938070 |
92 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.06446610 |
93 | * PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.05312670 |
94 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.04869053 |
95 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.04554473 |
96 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.04367053 |
97 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.04174983 |
98 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.04144510 |
99 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.03185856 |
100 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.02838216 |
101 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.02671029 |
102 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.02425028 |
103 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.01222128 |
104 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.00779693 |
105 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.00421168 |
106 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.00286976 |
107 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.99028954 |
108 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.98683850 |
109 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.98605034 |
110 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.98351938 |
111 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98318145 |
112 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.98077668 |
113 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.96899156 |
114 | GATA2_19941826_ChIP-Seq_K562_Human | 0.96667326 |
115 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.95734640 |
116 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.95435376 |
117 | CJUN_26792858_Chip-Seq_BT549_Human | 0.95274260 |
118 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.95160208 |
119 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.95011598 |
120 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.94834658 |
121 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.94161404 |
122 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.94056836 |
123 | GATA1_19941826_ChIP-Seq_K562_Human | 0.93614224 |
124 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.93569455 |
125 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.93352231 |
126 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.91203804 |
127 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.90980977 |
128 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.90451055 |
129 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.89539262 |
130 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.88909167 |
131 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.88737966 |
132 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.87538841 |
133 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.87342049 |
134 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 0.87247491 |
135 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.87104921 |
136 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.86746711 |
137 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.86595360 |
138 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.86468560 |
139 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.86258562 |
140 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.85936452 |
141 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.85619200 |
142 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.85253873 |
143 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84852078 |
144 | SPI1_23127762_ChIP-Seq_K562_Human | 0.83351588 |
145 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.82052291 |
146 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.82046420 |
147 | TP53_16413492_ChIP-PET_HCT116_Human | 0.80653569 |
148 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.80129122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003646_muscle_fatigue | 5.66084712 |
2 | MP0002837_dystrophic_cardiac_calcinosis | 5.64538514 |
3 | MP0004084_abnormal_cardiac_muscle | 5.03343054 |
4 | MP0000751_myopathy | 4.78586436 |
5 | MP0004215_abnormal_myocardial_fiber | 3.97872432 |
6 | MP0004036_abnormal_muscle_relaxation | 3.88951391 |
7 | MP0000749_muscle_degeneration | 3.50800911 |
8 | * MP0005330_cardiomyopathy | 3.30518613 |
9 | MP0004130_abnormal_muscle_cell | 3.08554136 |
10 | * MP0004087_abnormal_muscle_fiber | 3.06107981 |
11 | MP0002972_abnormal_cardiac_muscle | 2.83745713 |
12 | MP0000750_abnormal_muscle_regeneration | 2.73896207 |
13 | MP0005620_abnormal_muscle_contractility | 2.66294052 |
14 | MP0008775_abnormal_heart_ventricle | 2.66280541 |
15 | MP0002106_abnormal_muscle_physiology | 2.53954456 |
16 | MP0004145_abnormal_muscle_electrophysio | 2.51494177 |
17 | * MP0005385_cardiovascular_system_phenoty | 2.43019776 |
18 | * MP0001544_abnormal_cardiovascular_syste | 2.43019776 |
19 | MP0000747_muscle_weakness | 2.41982280 |
20 | * MP0004484_altered_response_of | 2.40457310 |
21 | * MP0010630_abnormal_cardiac_muscle | 2.39742629 |
22 | MP0006138_congestive_heart_failure | 2.37229036 |
23 | MP0003137_abnormal_impulse_conducting | 2.28901908 |
24 | MP0002269_muscular_atrophy | 2.22265260 |
25 | MP0003724_increased_susceptibility_to | 2.20983545 |
26 | MP0005409_darkened_coat_color | 2.17746832 |
27 | MP0000759_abnormal_skeletal_muscle | 2.13883727 |
28 | MP0005666_abnormal_adipose_tissue | 2.12290946 |
29 | MP0005369_muscle_phenotype | 2.10193679 |
30 | MP0003221_abnormal_cardiomyocyte_apopto | 2.03833092 |
31 | MP0004185_abnormal_adipocyte_glucose | 1.98500428 |
32 | MP0003828_pulmonary_edema | 1.97959796 |
33 | MP0003705_abnormal_hypodermis_morpholog | 1.96925802 |
34 | MP0004233_abnormal_muscle_weight | 1.82737229 |
35 | MP0004085_abnormal_heartbeat | 1.80019885 |
36 | MP0003191_abnormal_cellular_cholesterol | 1.71703826 |
37 | MP0003300_gastrointestinal_ulcer | 1.65104170 |
38 | MP0005375_adipose_tissue_phenotype | 1.57784480 |
39 | MP0003303_peritoneal_inflammation | 1.54308724 |
40 | MP0004510_myositis | 1.49616580 |
41 | MP0003690_abnormal_glial_cell | 1.48636391 |
42 | MP0006036_abnormal_mitochondrial_physio | 1.48101131 |
43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46769070 |
44 | MP0002009_preneoplasia | 1.43512191 |
45 | MP0003950_abnormal_plasma_membrane | 1.42300225 |
46 | MP0005670_abnormal_white_adipose | 1.39369167 |
47 | MP0005623_abnormal_meninges_morphology | 1.37267632 |
48 | MP0001661_extended_life_span | 1.33827052 |
49 | MP0002127_abnormal_cardiovascular_syste | 1.31931291 |
50 | MP0003091_abnormal_cell_migration | 1.31042969 |
51 | MP0008260_abnormal_autophagy | 1.29832762 |
52 | MP0002332_abnormal_exercise_endurance | 1.28708247 |
53 | MP0005085_abnormal_gallbladder_physiolo | 1.27869600 |
54 | MP0008438_abnormal_cutaneous_collagen | 1.26741732 |
55 | MP0002234_abnormal_pharynx_morphology | 1.25964264 |
56 | MP0000003_abnormal_adipose_tissue | 1.16600465 |
57 | MP0003252_abnormal_bile_duct | 1.15889257 |
58 | MP0000013_abnormal_adipose_tissue | 1.14149655 |
59 | MP0002132_abnormal_respiratory_system | 1.12364944 |
60 | MP0000733_abnormal_muscle_development | 1.10895753 |
61 | MP0005076_abnormal_cell_differentiation | 1.09331634 |
62 | MP0005083_abnormal_biliary_tract | 1.07794517 |
63 | * MP0000266_abnormal_heart_morphology | 1.07623456 |
64 | MP0004272_abnormal_basement_membrane | 1.06909049 |
65 | MP0003183_abnormal_peptide_metabolism | 1.06337839 |
66 | MP0000569_abnormal_digit_pigmentation | 1.05868963 |
67 | MP0000920_abnormal_myelination | 1.05765467 |
68 | MP0002108_abnormal_muscle_morphology | 1.05341045 |
69 | MP0003868_abnormal_feces_composition | 1.02194034 |
70 | MP0005275_abnormal_skin_tensile | 1.01300574 |
71 | MP0002971_abnormal_brown_adipose | 0.99787924 |
72 | MP0002139_abnormal_hepatobiliary_system | 0.97594082 |
73 | MP0002909_abnormal_adrenal_gland | 0.97078124 |
74 | MP0004270_analgesia | 0.96172328 |
75 | MP0005248_abnormal_Harderian_gland | 0.95941105 |
76 | MP0000343_altered_response_to | 0.95047098 |
77 | MP0003566_abnormal_cell_adhesion | 0.92168223 |
78 | MP0010368_abnormal_lymphatic_system | 0.91785797 |
79 | MP0009780_abnormal_chondrocyte_physiolo | 0.91020097 |
80 | MP0005165_increased_susceptibility_to | 0.89214356 |
81 | MP0004043_abnormal_pH_regulation | 0.88818433 |
82 | MP0004883_abnormal_blood_vessel | 0.87494887 |
83 | MP0001915_intracranial_hemorrhage | 0.84194078 |
84 | MP0001958_emphysema | 0.79877730 |
85 | MP0004381_abnormal_hair_follicle | 0.78721676 |
86 | MP0002138_abnormal_hepatobiliary_system | 0.77999908 |
87 | MP0008874_decreased_physiological_sensi | 0.77411320 |
88 | MP0005166_decreased_susceptibility_to | 0.76714756 |
89 | MP0005164_abnormal_response_to | 0.75780082 |
90 | MP0008961_abnormal_basal_metabolism | 0.75119357 |
91 | * MP0002128_abnormal_blood_circulation | 0.74434710 |
92 | MP0009840_abnormal_foam_cell | 0.71568423 |
93 | MP0003279_aneurysm | 0.71565890 |
94 | MP0000230_abnormal_systemic_arterial | 0.70434742 |
95 | MP0002166_altered_tumor_susceptibility | 0.68408043 |
96 | MP0001851_eye_inflammation | 0.68103247 |
97 | MP0003656_abnormal_erythrocyte_physiolo | 0.67936817 |
98 | MP0001879_abnormal_lymphatic_vessel | 0.67687752 |
99 | MP0010678_abnormal_skin_adnexa | 0.67015897 |
100 | MP0005187_abnormal_penis_morphology | 0.66228046 |
101 | MP0003634_abnormal_glial_cell | 0.65695883 |
102 | MP0006035_abnormal_mitochondrial_morpho | 0.64926099 |
103 | MP0005058_abnormal_lysosome_morphology | 0.64538602 |
104 | MP0003879_abnormal_hair_cell | 0.63248231 |
105 | MP0002877_abnormal_melanocyte_morpholog | 0.62322801 |
106 | MP0009384_cardiac_valve_regurgitation | 0.59000341 |
107 | MP0003632_abnormal_nervous_system | 0.58464967 |
108 | MP0002998_abnormal_bone_remodeling | 0.57607063 |
109 | MP0005365_abnormal_bile_salt | 0.56993759 |
110 | MP0000465_gastrointestinal_hemorrhage | 0.56895981 |
111 | MP0005451_abnormal_body_composition | 0.56502615 |
112 | MP0002419_abnormal_innate_immunity | 0.56048043 |
113 | MP0002078_abnormal_glucose_homeostasis | 0.55986851 |
114 | * MP0002925_abnormal_cardiovascular_devel | 0.54294781 |
115 | MP0003045_fibrosis | 0.50677257 |
116 | MP0005266_abnormal_metabolism | 0.49779491 |
117 | MP0005334_abnormal_fat_pad | 0.48997467 |
118 | MP0004858_abnormal_nervous_system | 0.47690864 |
119 | MP0000767_abnormal_smooth_muscle | 0.47480388 |
120 | MP0005535_abnormal_body_temperature | 0.44574398 |
121 | MP0003195_calcinosis | 0.44564034 |
122 | MP0001784_abnormal_fluid_regulation | 0.44500646 |
123 | * MP0001614_abnormal_blood_vessel | 0.43369082 |
124 | MP0002088_abnormal_embryonic_growth/wei | 0.43117581 |
125 | MP0003984_embryonic_growth_retardation | 0.42845618 |
126 | MP0002118_abnormal_lipid_homeostasis | 0.42684008 |
127 | MP0002295_abnormal_pulmonary_circulatio | 0.42403920 |
128 | MP0003329_amyloid_beta_deposits | 0.40048991 |
129 | MP0005167_abnormal_blood-brain_barrier | 0.37532466 |
130 | MP0009115_abnormal_fat_cell | 0.37506120 |
131 | MP0010234_abnormal_vibrissa_follicle | 0.36971289 |
132 | MP0003948_abnormal_gas_homeostasis | 0.36809320 |
133 | MP0002970_abnormal_white_adipose | 0.36690432 |
134 | MP0002896_abnormal_bone_mineralization | 0.36098016 |
135 | MP0005595_abnormal_vascular_smooth | 0.35861587 |
136 | MP0010352_gastrointestinal_tract_polyps | 0.35555904 |
137 | MP0001299_abnormal_eye_distance/ | 0.35207918 |
138 | MP0001727_abnormal_embryo_implantation | 0.34763352 |
139 | MP0008569_lethality_at_weaning | 0.34283014 |
140 | MP0005332_abnormal_amino_acid | 0.34121307 |
141 | MP0002090_abnormal_vision | 0.32797239 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 6.70386572 |
2 | Exercise-induced muscle cramps (HP:0003710) | 6.45029927 |
3 | Exercise-induced myalgia (HP:0003738) | 5.90603694 |
4 | Calf muscle hypertrophy (HP:0008981) | 5.72821658 |
5 | Ventricular tachycardia (HP:0004756) | 5.54696579 |
6 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.45233247 |
7 | Muscle fiber splitting (HP:0003555) | 5.40963993 |
8 | Myoglobinuria (HP:0002913) | 5.35201021 |
9 | Hyporeflexia of lower limbs (HP:0002600) | 4.83304087 |
10 | Atrial fibrillation (HP:0005110) | 4.81020492 |
11 | Abnormality of the calf musculature (HP:0001430) | 4.63273916 |
12 | Primary atrial arrhythmia (HP:0001692) | 4.50982523 |
13 | Bundle branch block (HP:0011710) | 4.36701142 |
14 | Supraventricular tachycardia (HP:0004755) | 4.30710821 |
15 | Lipoatrophy (HP:0100578) | 4.27350669 |
16 | Right ventricular cardiomyopathy (HP:0011663) | 4.24564979 |
17 | Supraventricular arrhythmia (HP:0005115) | 4.24389945 |
18 | Difficulty running (HP:0009046) | 4.23528925 |
19 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.23297374 |
20 | Subaortic stenosis (HP:0001682) | 4.23297374 |
21 | Rhabdomyolysis (HP:0003201) | 4.09151127 |
22 | Increased connective tissue (HP:0009025) | 3.91950489 |
23 | EMG: myopathic abnormalities (HP:0003458) | 3.91281896 |
24 | Syncope (HP:0001279) | 3.89911399 |
25 | Asymmetric septal hypertrophy (HP:0001670) | 3.65371666 |
26 | Dilated cardiomyopathy (HP:0001644) | 3.56772034 |
27 | Palpitations (HP:0001962) | 3.52061820 |
28 | Distal arthrogryposis (HP:0005684) | 3.49283376 |
29 | Prolonged QT interval (HP:0001657) | 3.49220597 |
30 | Heart block (HP:0012722) | 3.41600552 |
31 | Ventricular arrhythmia (HP:0004308) | 3.41127221 |
32 | Atrioventricular block (HP:0001678) | 3.36214038 |
33 | Ventricular fibrillation (HP:0001663) | 3.31876600 |
34 | Muscle fiber inclusion bodies (HP:0100299) | 3.31045037 |
35 | Abnormal atrioventricular conduction (HP:0005150) | 3.25571999 |
36 | Myotonia (HP:0002486) | 3.23253394 |
37 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.21977782 |
38 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.20577717 |
39 | Difficulty climbing stairs (HP:0003551) | 3.18076396 |
40 | Type 1 muscle fiber predominance (HP:0003803) | 3.16452975 |
41 | Muscle stiffness (HP:0003552) | 3.00279650 |
42 | Increased variability in muscle fiber diameter (HP:0003557) | 2.95786798 |
43 | Conjunctival hamartoma (HP:0100780) | 2.76105984 |
44 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.72289440 |
45 | Hypoglycemic coma (HP:0001325) | 2.69972958 |
46 | Ketoacidosis (HP:0001993) | 2.68981256 |
47 | Ulnar deviation of the wrist (HP:0003049) | 2.66931140 |
48 | Nemaline bodies (HP:0003798) | 2.61001265 |
49 | Arterial tortuosity (HP:0005116) | 2.50799786 |
50 | Eczematoid dermatitis (HP:0000976) | 2.47951700 |
51 | Dysmetric saccades (HP:0000641) | 2.47085077 |
52 | Abnormal EKG (HP:0003115) | 2.45162641 |
53 | Calcaneovalgus deformity (HP:0001848) | 2.40846164 |
54 | Neck muscle weakness (HP:0000467) | 2.38750723 |
55 | Bulbar palsy (HP:0001283) | 2.37115053 |
56 | Hamartoma of the eye (HP:0010568) | 2.32939936 |
57 | Broad metatarsal (HP:0001783) | 2.32639351 |
58 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.29885800 |
59 | Pheochromocytoma (HP:0002666) | 2.29865245 |
60 | Vascular tortuosity (HP:0004948) | 2.29637384 |
61 | Limb-girdle muscle atrophy (HP:0003797) | 2.25503694 |
62 | Cerebral aneurysm (HP:0004944) | 2.20169534 |
63 | Round ear (HP:0100830) | 2.20154536 |
64 | Deep venous thrombosis (HP:0002625) | 2.19772616 |
65 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.18351535 |
66 | Dicarboxylic aciduria (HP:0003215) | 2.18351535 |
67 | Areflexia of lower limbs (HP:0002522) | 2.18295374 |
68 | Left ventricular hypertrophy (HP:0001712) | 2.16359839 |
69 | Palmoplantar keratoderma (HP:0000982) | 2.12781657 |
70 | Hepatic necrosis (HP:0002605) | 2.11112976 |
71 | Athetosis (HP:0002305) | 2.10010789 |
72 | Peritonitis (HP:0002586) | 2.09668802 |
73 | Scapular winging (HP:0003691) | 2.07754857 |
74 | Myopathic facies (HP:0002058) | 2.04932793 |
75 | Protrusio acetabuli (HP:0003179) | 2.04311122 |
76 | Hypoplastic ischia (HP:0003175) | 2.03091293 |
77 | Distal lower limb muscle weakness (HP:0009053) | 2.01931711 |
78 | Deformed tarsal bones (HP:0008119) | 1.99612241 |
79 | Rimmed vacuoles (HP:0003805) | 1.98872843 |
80 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.98126354 |
81 | Spontaneous hematomas (HP:0007420) | 1.96964052 |
82 | Absent phalangeal crease (HP:0006109) | 1.96258817 |
83 | Sudden cardiac death (HP:0001645) | 1.93873668 |
84 | Lymphangioma (HP:0100764) | 1.93066838 |
85 | Increased muscle lipid content (HP:0009058) | 1.92927808 |
86 | Ketosis (HP:0001946) | 1.90765382 |
87 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.90354402 |
88 | Distal lower limb amyotrophy (HP:0008944) | 1.89598564 |
89 | Neuroendocrine neoplasm (HP:0100634) | 1.89508446 |
90 | Testicular atrophy (HP:0000029) | 1.88817103 |
91 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.88180864 |
92 | Abnormality of the foot musculature (HP:0001436) | 1.86955120 |
93 | Hyperglycemia (HP:0003074) | 1.86533802 |
94 | Amyloidosis (HP:0011034) | 1.86129847 |
95 | Muscular dystrophy (HP:0003560) | 1.85083779 |
96 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.84852042 |
97 | Papillary thyroid carcinoma (HP:0002895) | 1.84728929 |
98 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.83768962 |
99 | Aortic aneurysm (HP:0004942) | 1.83660230 |
100 | Foot dorsiflexor weakness (HP:0009027) | 1.83618520 |
101 | Congestive heart failure (HP:0001635) | 1.82438688 |
102 | Proximal amyotrophy (HP:0007126) | 1.81529482 |
103 | Vertebral arch anomaly (HP:0008438) | 1.81320980 |
104 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.80826418 |
105 | Abnormality of alanine metabolism (HP:0010916) | 1.80826418 |
106 | Hyperalaninemia (HP:0003348) | 1.80826418 |
107 | EMG: neuropathic changes (HP:0003445) | 1.78390426 |
108 | Large for gestational age (HP:0001520) | 1.78374929 |
109 | Gowers sign (HP:0003391) | 1.77766166 |
110 | Facial diplegia (HP:0001349) | 1.77406293 |
111 | Rapidly progressive (HP:0003678) | 1.76029866 |
112 | Frequent falls (HP:0002359) | 1.74216625 |
113 | Acute necrotizing encephalopathy (HP:0006965) | 1.73627124 |
114 | Subacute progressive viral hepatitis (HP:0006572) | 1.73465487 |
115 | Limb-girdle muscle weakness (HP:0003325) | 1.73250387 |
116 | Generalized muscle weakness (HP:0003324) | 1.73051748 |
117 | Cholecystitis (HP:0001082) | 1.72128890 |
118 | Abnormal gallbladder physiology (HP:0012438) | 1.72128890 |
119 | Hyperkalemia (HP:0002153) | 1.71602292 |
120 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.71519772 |
121 | Abnormality of the ischium (HP:0003174) | 1.71261884 |
122 | Mitral stenosis (HP:0001718) | 1.71058779 |
123 | Hyperglycinuria (HP:0003108) | 1.70292215 |
124 | Hypoalphalipoproteinemia (HP:0003233) | 1.69816950 |
125 | Neoplasm of the adrenal gland (HP:0100631) | 1.69199473 |
126 | Spinal rigidity (HP:0003306) | 1.67796407 |
127 | Abnormality of the calcaneus (HP:0008364) | 1.67581987 |
128 | Abnormality of the endocardium (HP:0004306) | 1.67180722 |
129 | Orchitis (HP:0100796) | 1.66344063 |
130 | Hypoplasia of the iris (HP:0007676) | 1.65797872 |
131 | Hypercortisolism (HP:0001578) | 1.63541811 |
132 | Myositis (HP:0100614) | 1.63220338 |
133 | Increased IgE level (HP:0003212) | 1.62536147 |
134 | Lower limb amyotrophy (HP:0007210) | 1.62472455 |
135 | Gastrointestinal infarctions (HP:0005244) | 1.60731105 |
136 | Cerebral inclusion bodies (HP:0100314) | 1.60544682 |
137 | Abnormal finger flexion creases (HP:0006143) | 1.60143839 |
138 | Increased CSF protein (HP:0002922) | 1.58855826 |
139 | Fetal akinesia sequence (HP:0001989) | 1.56011695 |
140 | Malignant hyperthermia (HP:0002047) | 1.54990570 |
141 | Neurofibrillary tangles (HP:0002185) | 1.54400738 |
142 | Cubitus valgus (HP:0002967) | 1.52794237 |
143 | Onion bulb formation (HP:0003383) | 1.51119484 |
144 | Testicular neoplasm (HP:0010788) | 1.50244953 |
145 | Mitral valve prolapse (HP:0001634) | 1.49449595 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 5.53624358 |
2 | TRIB3 | 4.53329516 |
3 | PKN2 | 4.25495180 |
4 | OBSCN | 3.63190368 |
5 | PHKG2 | 3.44855879 |
6 | PHKG1 | 3.44855879 |
7 | PDK3 | 3.12092927 |
8 | PDK4 | 3.12092927 |
9 | DMPK | 2.91648129 |
10 | LMTK2 | 2.76830101 |
11 | NEK1 | 2.34262500 |
12 | MAP3K6 | 2.27376039 |
13 | PRPF4B | 2.02339221 |
14 | MYLK | 1.90127168 |
15 | MAP3K2 | 1.79958164 |
16 | BCKDK | 1.79806725 |
17 | PIK3CG | 1.74778114 |
18 | PDK2 | 1.72894617 |
19 | STK24 | 1.68448948 |
20 | MAP3K13 | 1.61929300 |
21 | MAPK7 | 1.54740127 |
22 | PIK3CA | 1.51691858 |
23 | MOS | 1.51391773 |
24 | ERN1 | 1.47210467 |
25 | PINK1 | 1.47042333 |
26 | PDGFRA | 1.37677801 |
27 | RIPK1 | 1.36228532 |
28 | FGFR3 | 1.35118828 |
29 | ILK | 1.33302348 |
30 | YES1 | 1.31641699 |
31 | TGFBR2 | 1.25675870 |
32 | LATS1 | 1.25611926 |
33 | PAK3 | 1.23814570 |
34 | PRKD1 | 1.22907345 |
35 | TAOK3 | 1.21448225 |
36 | SGK2 | 1.18480604 |
37 | ZAP70 | 1.18479980 |
38 | CSK | 1.15271408 |
39 | NEK9 | 1.11265034 |
40 | WNK4 | 1.08020598 |
41 | PRKD3 | 1.02259721 |
42 | PTK6 | 1.02095381 |
43 | TYK2 | 1.02002589 |
44 | TIE1 | 1.00367554 |
45 | MAP2K6 | 0.99669841 |
46 | MAP3K7 | 0.98545939 |
47 | BLK | 0.97390471 |
48 | PBK | 0.95810593 |
49 | TAOK1 | 0.95410409 |
50 | EPHB1 | 0.95214283 |
51 | RET | 0.95052848 |
52 | SCYL2 | 0.94658384 |
53 | KSR2 | 0.94180993 |
54 | IRAK4 | 0.93198937 |
55 | MARK1 | 0.89084796 |
56 | LRRK2 | 0.88983932 |
57 | EEF2K | 0.87651721 |
58 | MAPK12 | 0.87490484 |
59 | SGK494 | 0.86262410 |
60 | SGK223 | 0.86262410 |
61 | RIPK4 | 0.84751455 |
62 | MAP2K3 | 0.84673642 |
63 | CAMK2D | 0.84145490 |
64 | SIK1 | 0.83436835 |
65 | LATS2 | 0.83112840 |
66 | STK38 | 0.82340079 |
67 | MARK2 | 0.80964003 |
68 | PRKAA1 | 0.80942958 |
69 | NTRK1 | 0.80037535 |
70 | RAF1 | 0.79847833 |
71 | JAK2 | 0.77855561 |
72 | MAP3K5 | 0.77095293 |
73 | PDPK1 | 0.77061666 |
74 | ICK | 0.76356579 |
75 | ROCK1 | 0.76187266 |
76 | FLT3 | 0.74474735 |
77 | PAK6 | 0.73915260 |
78 | PRKAA2 | 0.70378812 |
79 | WNK1 | 0.69236317 |
80 | FGFR4 | 0.68984673 |
81 | EPHB2 | 0.67926000 |
82 | RPS6KB1 | 0.66043629 |
83 | TRPM7 | 0.65306187 |
84 | MUSK | 0.64431022 |
85 | MAP2K1 | 0.63204936 |
86 | PRKCH | 0.62657064 |
87 | STK38L | 0.62134475 |
88 | PDK1 | 0.62098953 |
89 | ROCK2 | 0.62043845 |
90 | CAMK1G | 0.61836602 |
91 | STK39 | 0.61296802 |
92 | DYRK1B | 0.60466453 |
93 | CAMK1D | 0.57938020 |
94 | CAMK4 | 0.57477092 |
95 | AKT3 | 0.55037303 |
96 | SGK3 | 0.54819582 |
97 | CDC42BPA | 0.54786835 |
98 | NTRK3 | 0.53499592 |
99 | MAP3K3 | 0.52613672 |
100 | HCK | 0.52057713 |
101 | IRAK2 | 0.51853726 |
102 | CDK6 | 0.51589670 |
103 | CAMKK1 | 0.51068846 |
104 | GRK7 | 0.51037081 |
105 | TAOK2 | 0.50985213 |
106 | MST1R | 0.50957251 |
107 | MAP3K10 | 0.50688792 |
108 | MAP2K4 | 0.49786048 |
109 | MAPK11 | 0.49421252 |
110 | FES | 0.49360925 |
111 | PDGFRB | 0.49278470 |
112 | ALK | 0.49274329 |
113 | PKN1 | 0.48061945 |
114 | FGFR1 | 0.47823498 |
115 | FER | 0.47771007 |
116 | CDK12 | 0.47240668 |
117 | MAP3K9 | 0.46078809 |
118 | STK11 | 0.46028596 |
119 | CAMK1 | 0.45244103 |
120 | MTOR | 0.44994782 |
121 | DAPK3 | 0.44021822 |
122 | PRKG2 | 0.43422937 |
123 | TBK1 | 0.43141169 |
124 | BMX | 0.40242230 |
125 | MET | 0.39699962 |
126 | ARAF | 0.39186675 |
127 | CAMK2A | 0.39042907 |
128 | STK4 | 0.38916796 |
129 | EPHA3 | 0.37919551 |
130 | BMPR2 | 0.37263073 |
131 | MAP3K1 | 0.35000750 |
132 | NME1 | 0.33950766 |
133 | FGFR2 | 0.33846535 |
134 | AKT2 | 0.33842932 |
135 | KSR1 | 0.32115430 |
136 | CAMK2G | 0.31008923 |
137 | RPS6KC1 | 0.30892821 |
138 | RPS6KL1 | 0.30892821 |
139 | MAP3K4 | 0.30840041 |
140 | PRKACB | 0.30477071 |
141 | PRKACG | 0.30347627 |
142 | PTK2B | 0.29553995 |
143 | RPS6KA1 | 0.28382778 |
144 | SGK1 | 0.27908680 |
145 | JAK1 | 0.27341949 |
146 | PRKCE | 0.27272266 |
147 | PTK2 | 0.26222672 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 5.28598493 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.83325709 |
3 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.17107405 |
4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.16295027 |
5 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.13380036 |
6 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 3.02072372 |
7 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.67426280 |
8 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.66186056 |
9 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.54540342 |
10 | Carbon metabolism_Homo sapiens_hsa01200 | 2.34824767 |
11 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.29855081 |
12 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.24295791 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.21811300 |
14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.92737524 |
15 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.71049449 |
16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.67909890 |
17 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.61742932 |
18 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.53947245 |
19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.53687524 |
20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.51667068 |
21 | Viral myocarditis_Homo sapiens_hsa05416 | 1.46929694 |
22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.42967433 |
23 | Insulin resistance_Homo sapiens_hsa04931 | 1.34366860 |
24 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.29725246 |
25 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.28811255 |
26 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.21383108 |
27 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.19998143 |
28 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.18913400 |
29 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.18786579 |
30 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.18065995 |
31 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.12899543 |
32 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.12470169 |
33 | AMPK signaling pathway_Homo sapiens_hsa04152 | 1.11956616 |
34 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.09831393 |
35 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.09007001 |
36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.07733928 |
37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.07111123 |
38 | Focal adhesion_Homo sapiens_hsa04510 | 1.05653310 |
39 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.05636454 |
40 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.04807731 |
41 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03184307 |
42 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.03019377 |
43 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.02138328 |
44 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.99269880 |
45 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.98901783 |
46 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.98770509 |
47 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.98633218 |
48 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.97935717 |
49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.97723160 |
50 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.92879070 |
51 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.91965654 |
52 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.91118699 |
53 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.90462951 |
54 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.88665885 |
55 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.87374260 |
56 | Prion diseases_Homo sapiens_hsa05020 | 0.85207180 |
57 | Tight junction_Homo sapiens_hsa04530 | 0.85179675 |
58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.84686224 |
59 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84322565 |
60 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.83954396 |
61 | Leishmaniasis_Homo sapiens_hsa05140 | 0.82469953 |
62 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.82467185 |
63 | * HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.82024618 |
64 | Long-term depression_Homo sapiens_hsa04730 | 0.81726510 |
65 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.80541096 |
66 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.79864727 |
67 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.77631180 |
68 | Lysine degradation_Homo sapiens_hsa00310 | 0.77414834 |
69 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.75798885 |
70 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.75476050 |
71 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.75030390 |
72 | * Renal cell carcinoma_Homo sapiens_hsa05211 | 0.73554278 |
73 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.73424235 |
74 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.73198447 |
75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71080421 |
76 | Tuberculosis_Homo sapiens_hsa05152 | 0.68111649 |
77 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.67915037 |
78 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.67745279 |
79 | Renin secretion_Homo sapiens_hsa04924 | 0.67737756 |
80 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.67639608 |
81 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.66805867 |
82 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.66188085 |
83 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.65402490 |
84 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.63691560 |
85 | Adherens junction_Homo sapiens_hsa04520 | 0.62072191 |
86 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.61881885 |
87 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60654937 |
88 | Galactose metabolism_Homo sapiens_hsa00052 | 0.60533173 |
89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.59536592 |
90 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.59520998 |
91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59351447 |
92 | Thyroid cancer_Homo sapiens_hsa05216 | 0.59054605 |
93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.55746534 |
94 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.55732178 |
95 | Amoebiasis_Homo sapiens_hsa05146 | 0.54523926 |
96 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.53577187 |
97 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.51221462 |
98 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.50909972 |
99 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.49924691 |
100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.49625727 |
101 | Prostate cancer_Homo sapiens_hsa05215 | 0.49437074 |
102 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.49426391 |
103 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.49026412 |
104 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.48385241 |
105 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.48122928 |
106 | Endocytosis_Homo sapiens_hsa04144 | 0.48055647 |
107 | Circadian rhythm_Homo sapiens_hsa04710 | 0.47355806 |
108 | Glioma_Homo sapiens_hsa05214 | 0.46522221 |
109 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.46345048 |
110 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.45925199 |
111 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.43880862 |
112 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.43619150 |
113 | Insulin secretion_Homo sapiens_hsa04911 | 0.43088529 |
114 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.42550530 |
115 | Gap junction_Homo sapiens_hsa04540 | 0.41738675 |
116 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.40471845 |
117 | Endometrial cancer_Homo sapiens_hsa05213 | 0.40210431 |
118 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.40139766 |
119 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39803315 |
120 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.39486020 |
121 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.38928058 |
122 | Long-term potentiation_Homo sapiens_hsa04720 | 0.38866980 |
123 | Circadian entrainment_Homo sapiens_hsa04713 | 0.38480456 |
124 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.37833318 |
125 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.37450228 |
126 | Melanogenesis_Homo sapiens_hsa04916 | 0.34670725 |
127 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.31451175 |
128 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.30449487 |
129 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.29635106 |
130 | Platelet activation_Homo sapiens_hsa04611 | 0.29005133 |
131 | Salivary secretion_Homo sapiens_hsa04970 | 0.27639222 |
132 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.27359846 |
133 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.26512358 |
134 | Bile secretion_Homo sapiens_hsa04976 | 0.26383948 |
135 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.25811757 |
136 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.25201523 |
137 | Peroxisome_Homo sapiens_hsa04146 | 0.24291202 |
138 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.23953361 |