

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 5.23737711 |
| 2 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 5.09906215 |
| 3 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 4.84462890 |
| 4 | anterior/posterior axis specification, embryo (GO:0008595) | 4.82632721 |
| 5 | nodal signaling pathway (GO:0038092) | 4.74608765 |
| 6 | L-ascorbic acid metabolic process (GO:0019852) | 4.69567093 |
| 7 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.65903890 |
| 8 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.60242291 |
| 9 | regulation of sulfur metabolic process (GO:0042762) | 4.45487479 |
| 10 | regulation of coenzyme metabolic process (GO:0051196) | 4.22824991 |
| 11 | regulation of cofactor metabolic process (GO:0051193) | 4.22824991 |
| 12 | regulation of cholesterol esterification (GO:0010872) | 4.21802954 |
| 13 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 4.18336343 |
| 14 | female gonad development (GO:0008585) | 4.08143406 |
| 15 | positive regulation of cardiac muscle cell proliferation (GO:0060045) | 4.07474620 |
| 16 | embryonic foregut morphogenesis (GO:0048617) | 4.07246989 |
| 17 | phospholipid efflux (GO:0033700) | 3.98103020 |
| 18 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.88992538 |
| 19 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.80779280 |
| 20 | otic vesicle formation (GO:0030916) | 3.74614741 |
| 21 | cardiac right ventricle morphogenesis (GO:0003215) | 3.72606250 |
| 22 | cullin deneddylation (GO:0010388) | 3.67309413 |
| 23 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.67246323 |
| 24 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.67246323 |
| 25 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 3.65611262 |
| 26 | positive regulation of cardiac muscle tissue growth (GO:0055023) | 3.65257455 |
| 27 | endoderm formation (GO:0001706) | 3.64277320 |
| 28 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.63132966 |
| 29 | response to pheromone (GO:0019236) | 3.59905002 |
| 30 | somite rostral/caudal axis specification (GO:0032525) | 3.59516282 |
| 31 | kidney morphogenesis (GO:0060993) | 3.58278997 |
| 32 | negative regulation of activin receptor signaling pathway (GO:0032926) | 3.57870448 |
| 33 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.56530460 |
| 34 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.56530460 |
| 35 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.56530460 |
| 36 | negative regulation of lipase activity (GO:0060192) | 3.48353784 |
| 37 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 3.39995756 |
| 38 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 3.38439570 |
| 39 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.37810310 |
| 40 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.37810310 |
| 41 | positive regulation of glycoprotein metabolic process (GO:1903020) | 3.37252538 |
| 42 | regulation of mRNA 3-end processing (GO:0031440) | 3.36747966 |
| 43 | high-density lipoprotein particle remodeling (GO:0034375) | 3.36031717 |
| 44 | embryonic camera-type eye development (GO:0031076) | 3.34397209 |
| 45 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.30223001 |
| 46 | protein deneddylation (GO:0000338) | 3.29136938 |
| 47 | regulation of glucokinase activity (GO:0033131) | 3.28946029 |
| 48 | regulation of hexokinase activity (GO:1903299) | 3.28946029 |
| 49 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.27161025 |
| 50 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.27161025 |
| 51 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.26529066 |
| 52 | reverse cholesterol transport (GO:0043691) | 3.26180324 |
| 53 | positive regulation of heart growth (GO:0060421) | 3.25556461 |
| 54 | pericardium development (GO:0060039) | 3.25328619 |
| 55 | plasma lipoprotein particle assembly (GO:0034377) | 3.22743441 |
| 56 | positive regulation of mRNA catabolic process (GO:0061014) | 3.21497374 |
| 57 | response to gravity (GO:0009629) | 3.21482293 |
| 58 | signal transduction involved in regulation of gene expression (GO:0023019) | 3.19899961 |
| 59 | embryonic axis specification (GO:0000578) | 3.17075503 |
| 60 | protein autoprocessing (GO:0016540) | 3.16298246 |
| 61 | embryonic pattern specification (GO:0009880) | 3.16116231 |
| 62 | peptidyl-cysteine modification (GO:0018198) | 3.15923009 |
| 63 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.14456527 |
| 64 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.12160694 |
| 65 | lactate metabolic process (GO:0006089) | 3.09067067 |
| 66 | embryonic cranial skeleton morphogenesis (GO:0048701) | 3.08433595 |
| 67 | positive regulation of mRNA 3-end processing (GO:0031442) | 3.06559378 |
| 68 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.06475307 |
| 69 | regulation of activin receptor signaling pathway (GO:0032925) | 3.06332418 |
| 70 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.05773900 |
| 71 | primitive streak formation (GO:0090009) | 3.05447230 |
| 72 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.04697749 |
| 73 | branched-chain amino acid catabolic process (GO:0009083) | 3.01199807 |
| 74 | SMAD protein signal transduction (GO:0060395) | 3.00719074 |
| 75 | photoreceptor cell maintenance (GO:0045494) | 2.95181274 |
| 76 | embryonic digestive tract morphogenesis (GO:0048557) | 2.93910707 |
| 77 | protein-lipid complex assembly (GO:0065005) | 2.90782496 |
| 78 | regulation of cardiac muscle cell proliferation (GO:0060043) | 2.88113753 |
| 79 | sensory perception of smell (GO:0007608) | 2.83850086 |
| 80 | dopamine transport (GO:0015872) | 2.83509778 |
| 81 | regulation of cardioblast differentiation (GO:0051890) | 2.83506365 |
| 82 | DNA double-strand break processing (GO:0000729) | 2.81829875 |
| 83 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.80371403 |
| 84 | negative regulation of cholesterol transport (GO:0032375) | 2.74757997 |
| 85 | negative regulation of sterol transport (GO:0032372) | 2.74757997 |
| 86 | positive regulation of cardiac muscle tissue development (GO:0055025) | 2.74437389 |
| 87 | regulation of mRNA catabolic process (GO:0061013) | 2.70557409 |
| 88 | mRNA cleavage (GO:0006379) | 2.68177071 |
| 89 | cellular ketone body metabolic process (GO:0046950) | 2.66009735 |
| 90 | anterior/posterior axis specification (GO:0009948) | 2.64500239 |
| 91 | tricarboxylic acid cycle (GO:0006099) | 2.64047941 |
| 92 | regulation of mesoderm development (GO:2000380) | 2.63504810 |
| 93 | ventricular cardiac muscle cell development (GO:0055015) | 2.63342995 |
| 94 | regulation of tight junction assembly (GO:2000810) | 2.61411194 |
| 95 | positive regulation of gastrulation (GO:2000543) | 2.61004561 |
| 96 | GPI anchor metabolic process (GO:0006505) | 2.56303387 |
| 97 | peptidyl-histidine modification (GO:0018202) | 2.55430985 |
| 98 | regulation of acrosome reaction (GO:0060046) | 2.55262639 |
| 99 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.53194338 |
| 100 | proteasome assembly (GO:0043248) | 2.53122733 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.43038277 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.74351391 |
| 3 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.55896019 |
| 4 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.52181761 |
| 5 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.46774268 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.40254887 |
| 7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.31379055 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.22951244 |
| 9 | P300_19829295_ChIP-Seq_ESCs_Human | 2.13509472 |
| 10 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 2.04435048 |
| 11 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.01390530 |
| 12 | FUS_26573619_Chip-Seq_HEK293_Human | 1.99646648 |
| 13 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.95992364 |
| 14 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.95696846 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.94504735 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.92623119 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 1.88670109 |
| 18 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.82829182 |
| 19 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.80240107 |
| 20 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.79920051 |
| 21 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.76187904 |
| 22 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.66283552 |
| 23 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.63362805 |
| 24 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.60399231 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.60280121 |
| 26 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.59500862 |
| 27 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.56831172 |
| 28 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.56831172 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55624615 |
| 30 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.55429461 |
| 31 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.54355568 |
| 32 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.53381115 |
| 33 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.49273020 |
| 34 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.45563565 |
| 35 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.45252474 |
| 36 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.45252474 |
| 37 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.44261139 |
| 38 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.44182879 |
| 39 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.43929313 |
| 40 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.43718720 |
| 41 | STAT3_23295773_ChIP-Seq_U87_Human | 1.42832623 |
| 42 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.42772155 |
| 43 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.41800302 |
| 44 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.38646315 |
| 45 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.36868474 |
| 46 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.35718794 |
| 47 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.35407137 |
| 48 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.34401198 |
| 49 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.34385848 |
| 50 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.33098214 |
| 51 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.32640186 |
| 52 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.31524374 |
| 53 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.30185426 |
| 54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.30050245 |
| 55 | TP53_16413492_ChIP-PET_HCT116_Human | 1.29788338 |
| 56 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.29631656 |
| 57 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.29502578 |
| 58 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.26635464 |
| 59 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.25757872 |
| 60 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.25317630 |
| 61 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.24646701 |
| 62 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.24325550 |
| 63 | TCF4_23295773_ChIP-Seq_U87_Human | 1.22454304 |
| 64 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.22236787 |
| 65 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.21516751 |
| 66 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.21466888 |
| 67 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.20492965 |
| 68 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19902912 |
| 69 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.19062237 |
| 70 | EOMES_21245162_ChIP-Seq_HESCs_Human | 1.18146457 |
| 71 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.17887795 |
| 72 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.17887795 |
| 73 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.17887795 |
| 74 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.17697206 |
| 75 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16195476 |
| 76 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.16000941 |
| 77 | AR_25329375_ChIP-Seq_VCAP_Human | 1.14957571 |
| 78 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.13935910 |
| 79 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13428244 |
| 80 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.13006259 |
| 81 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.12637150 |
| 82 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.12597962 |
| 83 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.12346165 |
| 84 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.11645159 |
| 85 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.10121329 |
| 86 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.09271439 |
| 87 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.08027461 |
| 88 | CJUN_26792858_Chip-Seq_BT549_Human | 1.07952952 |
| 89 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.07798712 |
| 90 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.07377748 |
| 91 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.07375756 |
| 92 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.07315199 |
| 93 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.07006425 |
| 94 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.06630963 |
| 95 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.06497710 |
| 96 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.04284557 |
| 97 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.03742723 |
| 98 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.03036208 |
| 99 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.02486390 |
| 100 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.02040934 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 5.29038310 |
| 2 | MP0004264_abnormal_extraembryonic_tissu | 4.30381684 |
| 3 | MP0010030_abnormal_orbit_morphology | 3.91312481 |
| 4 | MP0003890_abnormal_embryonic-extraembry | 3.66620603 |
| 5 | MP0002938_white_spotting | 3.51579365 |
| 6 | MP0003136_yellow_coat_color | 3.00600148 |
| 7 | MP0008004_abnormal_stomach_pH | 2.90621977 |
| 8 | MP0004145_abnormal_muscle_electrophysio | 2.73281635 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.38736240 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.38447264 |
| 11 | MP0000516_abnormal_urinary_system | 2.17930200 |
| 12 | MP0005367_renal/urinary_system_phenotyp | 2.17930200 |
| 13 | MP0003191_abnormal_cellular_cholesterol | 2.09731628 |
| 14 | MP0004270_analgesia | 2.02037578 |
| 15 | MP0001299_abnormal_eye_distance/ | 1.91586312 |
| 16 | MP0000569_abnormal_digit_pigmentation | 1.88949789 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.84744979 |
| 18 | MP0003119_abnormal_digestive_system | 1.84587388 |
| 19 | MP0003950_abnormal_plasma_membrane | 1.81824429 |
| 20 | MP0009697_abnormal_copulation | 1.76924665 |
| 21 | MP0004133_heterotaxia | 1.75138530 |
| 22 | MP0002876_abnormal_thyroid_physiology | 1.74151162 |
| 23 | MP0005171_absent_coat_pigmentation | 1.68173890 |
| 24 | MP0000427_abnormal_hair_cycle | 1.67553024 |
| 25 | MP0008058_abnormal_DNA_repair | 1.66946703 |
| 26 | MP0002277_abnormal_respiratory_mucosa | 1.66711149 |
| 27 | MP0008057_abnormal_DNA_replication | 1.58912390 |
| 28 | MP0000749_muscle_degeneration | 1.56840329 |
| 29 | MP0003137_abnormal_impulse_conducting | 1.54251970 |
| 30 | MP0003195_calcinosis | 1.52844874 |
| 31 | MP0002234_abnormal_pharynx_morphology | 1.50151258 |
| 32 | MP0003943_abnormal_hepatobiliary_system | 1.47547188 |
| 33 | MP0005408_hypopigmentation | 1.43217879 |
| 34 | MP0010094_abnormal_chromosome_stability | 1.35348559 |
| 35 | MP0008260_abnormal_autophagy | 1.32618641 |
| 36 | MP0004215_abnormal_myocardial_fiber | 1.27615515 |
| 37 | MP0000015_abnormal_ear_pigmentation | 1.25540555 |
| 38 | MP0001986_abnormal_taste_sensitivity | 1.25408815 |
| 39 | MP0008872_abnormal_physiological_respon | 1.23268012 |
| 40 | MP0005174_abnormal_tail_pigmentation | 1.19153625 |
| 41 | MP0004381_abnormal_hair_follicle | 1.14855620 |
| 42 | MP0008789_abnormal_olfactory_epithelium | 1.12856494 |
| 43 | MP0009780_abnormal_chondrocyte_physiolo | 1.12331247 |
| 44 | MP0000647_abnormal_sebaceous_gland | 1.11048441 |
| 45 | MP0005075_abnormal_melanosome_morpholog | 1.08195096 |
| 46 | MP0003121_genomic_imprinting | 1.07447629 |
| 47 | MP0001764_abnormal_homeostasis | 1.07433876 |
| 48 | MP0004147_increased_porphyrin_level | 1.06682132 |
| 49 | MP0004142_abnormal_muscle_tone | 1.06420465 |
| 50 | MP0010329_abnormal_lipoprotein_level | 1.04362007 |
| 51 | MP0002254_reproductive_system_inflammat | 1.04353792 |
| 52 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01203942 |
| 53 | MP0003122_maternal_imprinting | 1.00424122 |
| 54 | MP0002233_abnormal_nose_morphology | 0.98598783 |
| 55 | MP0001486_abnormal_startle_reflex | 0.98301209 |
| 56 | MP0002168_other_aberrant_phenotype | 0.95021342 |
| 57 | MP0005248_abnormal_Harderian_gland | 0.93508356 |
| 58 | MP0006035_abnormal_mitochondrial_morpho | 0.91520048 |
| 59 | MP0005253_abnormal_eye_physiology | 0.88962538 |
| 60 | MP0002933_joint_inflammation | 0.86420319 |
| 61 | MP0006036_abnormal_mitochondrial_physio | 0.86344210 |
| 62 | MP0005499_abnormal_olfactory_system | 0.84858317 |
| 63 | MP0005394_taste/olfaction_phenotype | 0.84858317 |
| 64 | MP0008995_early_reproductive_senescence | 0.84646048 |
| 65 | MP0005332_abnormal_amino_acid | 0.83636326 |
| 66 | MP0002837_dystrophic_cardiac_calcinosis | 0.82995189 |
| 67 | MP0001485_abnormal_pinna_reflex | 0.82246216 |
| 68 | MP0003880_abnormal_central_pattern | 0.81668291 |
| 69 | MP0001324_abnormal_eye_pigmentation | 0.81108702 |
| 70 | MP0002139_abnormal_hepatobiliary_system | 0.80902779 |
| 71 | MP0001881_abnormal_mammary_gland | 0.80224739 |
| 72 | MP0006072_abnormal_retinal_apoptosis | 0.79383772 |
| 73 | MP0005330_cardiomyopathy | 0.79145804 |
| 74 | MP0000639_abnormal_adrenal_gland | 0.78713441 |
| 75 | MP0003186_abnormal_redox_activity | 0.78582435 |
| 76 | MP0000428_abnormal_craniofacial_morphol | 0.77988570 |
| 77 | MP0003828_pulmonary_edema | 0.77838924 |
| 78 | MP0000538_abnormal_urinary_bladder | 0.75928961 |
| 79 | MP0002736_abnormal_nociception_after | 0.74878198 |
| 80 | MP0006276_abnormal_autonomic_nervous | 0.74771819 |
| 81 | MP0009250_abnormal_appendicular_skeleto | 0.74185962 |
| 82 | MP0000383_abnormal_hair_follicle | 0.73677167 |
| 83 | MP0002160_abnormal_reproductive_system | 0.73095190 |
| 84 | MP0002734_abnormal_mechanical_nocicepti | 0.72937615 |
| 85 | MP0005084_abnormal_gallbladder_morpholo | 0.71885200 |
| 86 | MP0001929_abnormal_gametogenesis | 0.71843648 |
| 87 | MP0003786_premature_aging | 0.71541621 |
| 88 | MP0009703_decreased_birth_body | 0.71261947 |
| 89 | MP0008875_abnormal_xenobiotic_pharmacok | 0.69879328 |
| 90 | MP0002638_abnormal_pupillary_reflex | 0.69836295 |
| 91 | MP0002972_abnormal_cardiac_muscle | 0.68689188 |
| 92 | MP0005395_other_phenotype | 0.67641570 |
| 93 | MP0001286_abnormal_eye_development | 0.66943412 |
| 94 | MP0002282_abnormal_trachea_morphology | 0.64823805 |
| 95 | MP0004272_abnormal_basement_membrane | 0.64814064 |
| 96 | MP0009672_abnormal_birth_weight | 0.64493143 |
| 97 | MP0003936_abnormal_reproductive_system | 0.63779915 |
| 98 | MP0005023_abnormal_wound_healing | 0.63607385 |
| 99 | MP0009384_cardiac_valve_regurgitation | 0.62880879 |
| 100 | MP0003077_abnormal_cell_cycle | 0.62427708 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type 2 muscle fiber atrophy (HP:0003554) | 5.37941319 |
| 2 | Progressive inability to walk (HP:0002505) | 4.69096877 |
| 3 | Muscle fiber atrophy (HP:0100295) | 4.29333140 |
| 4 | Abnormality of the ischium (HP:0003174) | 3.99164293 |
| 5 | Congenital malformation of the right heart (HP:0011723) | 3.61143036 |
| 6 | Double outlet right ventricle (HP:0001719) | 3.61143036 |
| 7 | Abnormality of alanine metabolism (HP:0010916) | 3.54019055 |
| 8 | Hyperalaninemia (HP:0003348) | 3.54019055 |
| 9 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.54019055 |
| 10 | Hypoplastic ischia (HP:0003175) | 3.31195778 |
| 11 | Intestinal atresia (HP:0011100) | 3.20082074 |
| 12 | Aqueductal stenosis (HP:0002410) | 3.16324893 |
| 13 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 3.12024545 |
| 14 | Popliteal pterygium (HP:0009756) | 3.11606399 |
| 15 | Abnormality of the parathyroid morphology (HP:0011766) | 3.09219548 |
| 16 | Weak cry (HP:0001612) | 3.08639796 |
| 17 | Long clavicles (HP:0000890) | 3.08147353 |
| 18 | Abnormality of the neuromuscular junction (HP:0003398) | 3.00546709 |
| 19 | Fatigable weakness (HP:0003473) | 3.00546709 |
| 20 | Abnormality of the pubic bones (HP:0003172) | 2.85706079 |
| 21 | Decreased muscle mass (HP:0003199) | 2.71074963 |
| 22 | Pancreatic cysts (HP:0001737) | 2.70396604 |
| 23 | Anal stenosis (HP:0002025) | 2.70130956 |
| 24 | Abnormality of the renal cortex (HP:0011035) | 2.60213198 |
| 25 | Abdominal situs inversus (HP:0003363) | 2.59783255 |
| 26 | Abnormality of abdominal situs (HP:0011620) | 2.59783255 |
| 27 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.57172847 |
| 28 | Renal cortical cysts (HP:0000803) | 2.55903245 |
| 29 | Molar tooth sign on MRI (HP:0002419) | 2.52783457 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.52783457 |
| 31 | Easy fatigability (HP:0003388) | 2.50483829 |
| 32 | Bell-shaped thorax (HP:0001591) | 2.49101684 |
| 33 | Microglossia (HP:0000171) | 2.44645705 |
| 34 | Abnormal pancreas size (HP:0012094) | 2.38132887 |
| 35 | Neoplasm of the adrenal gland (HP:0100631) | 2.38037072 |
| 36 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.36525716 |
| 37 | True hermaphroditism (HP:0010459) | 2.35599528 |
| 38 | Hypoplastic iliac wings (HP:0002866) | 2.34584743 |
| 39 | Concave nail (HP:0001598) | 2.32997475 |
| 40 | Periauricular skin pits (HP:0100277) | 2.32166293 |
| 41 | Preauricular pit (HP:0004467) | 2.32166293 |
| 42 | Inability to walk (HP:0002540) | 2.29930990 |
| 43 | Anencephaly (HP:0002323) | 2.27487967 |
| 44 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.27279195 |
| 45 | Septo-optic dysplasia (HP:0100842) | 2.24633242 |
| 46 | Poikiloderma (HP:0001029) | 2.23706236 |
| 47 | Medial flaring of the eyebrow (HP:0010747) | 2.23065701 |
| 48 | Abnormal ventriculo-arterial connection (HP:0011563) | 2.21716320 |
| 49 | Transposition of the great arteries (HP:0001669) | 2.21716320 |
| 50 | Abnormal connection of the cardiac segments (HP:0011545) | 2.21716320 |
| 51 | Entropion (HP:0000621) | 2.21367348 |
| 52 | Short tibia (HP:0005736) | 2.20865018 |
| 53 | Hypoplasia of the iris (HP:0007676) | 2.19756576 |
| 54 | Ependymoma (HP:0002888) | 2.19139776 |
| 55 | Depressed nasal tip (HP:0000437) | 2.19007038 |
| 56 | Hypomagnesemia (HP:0002917) | 2.18979061 |
| 57 | Posterior subcapsular cataract (HP:0007787) | 2.18785031 |
| 58 | Nonprogressive disorder (HP:0003680) | 2.16002803 |
| 59 | Oligodactyly (hands) (HP:0001180) | 2.13598679 |
| 60 | Breast carcinoma (HP:0003002) | 2.12773214 |
| 61 | Pancreatic fibrosis (HP:0100732) | 2.12715028 |
| 62 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.10302953 |
| 63 | Single umbilical artery (HP:0001195) | 2.10302953 |
| 64 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.10302953 |
| 65 | Attenuation of retinal blood vessels (HP:0007843) | 2.07904556 |
| 66 | Neurodegeneration (HP:0002180) | 2.06591988 |
| 67 | Congenital primary aphakia (HP:0007707) | 2.04652787 |
| 68 | Nephronophthisis (HP:0000090) | 2.04418734 |
| 69 | Increased corneal curvature (HP:0100692) | 2.04132147 |
| 70 | Keratoconus (HP:0000563) | 2.04132147 |
| 71 | Stomach cancer (HP:0012126) | 2.02510724 |
| 72 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 2.00753709 |
| 73 | Hypoplastic scapulae (HP:0000882) | 2.00753709 |
| 74 | Absent septum pellucidum (HP:0001331) | 2.00489668 |
| 75 | Abnormality of DNA repair (HP:0003254) | 2.00279007 |
| 76 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.97997827 |
| 77 | Fibular aplasia (HP:0002990) | 1.97886022 |
| 78 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.97226742 |
| 79 | Patchy hypopigmentation of hair (HP:0011365) | 1.95562658 |
| 80 | Vaginal atresia (HP:0000148) | 1.94374443 |
| 81 | Genital tract atresia (HP:0001827) | 1.92927568 |
| 82 | Glioma (HP:0009733) | 1.90880629 |
| 83 | Neoplasm of the adrenal cortex (HP:0100641) | 1.90142770 |
| 84 | Gait imbalance (HP:0002141) | 1.90028079 |
| 85 | Ectropion (HP:0000656) | 1.88923784 |
| 86 | CNS demyelination (HP:0007305) | 1.87986997 |
| 87 | Neonatal respiratory distress (HP:0002643) | 1.87318332 |
| 88 | Amelogenesis imperfecta (HP:0000705) | 1.84661505 |
| 89 | Bifid tongue (HP:0010297) | 1.83182126 |
| 90 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.81887180 |
| 91 | Hypoplasia of the fovea (HP:0007750) | 1.81887180 |
| 92 | Proximal tubulopathy (HP:0000114) | 1.81277607 |
| 93 | Abnormality of the renal medulla (HP:0100957) | 1.79578319 |
| 94 | Esophageal atresia (HP:0002032) | 1.79068267 |
| 95 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.78486072 |
| 96 | Mesomelia (HP:0003027) | 1.78353519 |
| 97 | Hypoplasia of the pons (HP:0012110) | 1.77975252 |
| 98 | Chronic hepatic failure (HP:0100626) | 1.77382294 |
| 99 | Anteriorly placed anus (HP:0001545) | 1.76362557 |
| 100 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.75638515 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MUSK | 8.45099079 |
| 2 | PDK2 | 6.64238537 |
| 3 | FRK | 3.75251025 |
| 4 | ERBB4 | 3.65331298 |
| 5 | ACVR1B | 3.31585688 |
| 6 | MST4 | 3.22084929 |
| 7 | TNIK | 3.09915501 |
| 8 | PBK | 2.97227020 |
| 9 | TRIM28 | 2.86575163 |
| 10 | BMPR1B | 2.85726830 |
| 11 | ZAK | 2.26315673 |
| 12 | MAP3K12 | 1.94884481 |
| 13 | EIF2AK3 | 1.91109163 |
| 14 | SIK3 | 1.69402018 |
| 15 | TGFBR1 | 1.58340911 |
| 16 | MAP4K2 | 1.57869507 |
| 17 | FGFR2 | 1.54352817 |
| 18 | NLK | 1.42218285 |
| 19 | STK39 | 1.37174638 |
| 20 | WNK3 | 1.28108420 |
| 21 | MKNK2 | 1.27268021 |
| 22 | GRK1 | 1.20917222 |
| 23 | BRD4 | 1.18970329 |
| 24 | PLK3 | 1.13248821 |
| 25 | EPHA2 | 1.07755976 |
| 26 | TSSK6 | 1.02258298 |
| 27 | NEK1 | 0.91509989 |
| 28 | TTK | 0.88399869 |
| 29 | WEE1 | 0.88270179 |
| 30 | PAK3 | 0.85995119 |
| 31 | MAP3K9 | 0.85839278 |
| 32 | MELK | 0.83705168 |
| 33 | BCR | 0.79971364 |
| 34 | STK3 | 0.72039846 |
| 35 | AKT3 | 0.70550764 |
| 36 | BUB1 | 0.69024065 |
| 37 | PRKCE | 0.67184223 |
| 38 | OXSR1 | 0.66128597 |
| 39 | PNCK | 0.65122291 |
| 40 | MKNK1 | 0.64301561 |
| 41 | MYLK | 0.63833637 |
| 42 | ERBB3 | 0.63461156 |
| 43 | DAPK2 | 0.61123677 |
| 44 | FER | 0.60882274 |
| 45 | PLK2 | 0.56529083 |
| 46 | NUAK1 | 0.52418911 |
| 47 | STK4 | 0.51644408 |
| 48 | NEK6 | 0.50831149 |
| 49 | EIF2AK2 | 0.50327078 |
| 50 | PRKCI | 0.48839057 |
| 51 | MARK3 | 0.48477668 |
| 52 | FGFR1 | 0.48472636 |
| 53 | STK10 | 0.47074800 |
| 54 | STK38L | 0.47034938 |
| 55 | PIK3CG | 0.46477347 |
| 56 | MAP2K1 | 0.43639413 |
| 57 | BRSK2 | 0.43309695 |
| 58 | PLK1 | 0.40300503 |
| 59 | CHUK | 0.39840785 |
| 60 | TAOK3 | 0.39726169 |
| 61 | EPHA4 | 0.39127849 |
| 62 | MAP3K4 | 0.37801564 |
| 63 | INSRR | 0.35710031 |
| 64 | DAPK1 | 0.32607391 |
| 65 | CDK4 | 0.31454157 |
| 66 | PIK3CA | 0.27064671 |
| 67 | ADRBK1 | 0.26177614 |
| 68 | MAP3K2 | 0.25938246 |
| 69 | IKBKB | 0.24792460 |
| 70 | PRKCG | 0.23803838 |
| 71 | EGFR | 0.21568938 |
| 72 | CHEK2 | 0.20123478 |
| 73 | VRK1 | 0.19991989 |
| 74 | CSNK1D | 0.19205793 |
| 75 | PRKACB | 0.18881976 |
| 76 | TAF1 | 0.18693642 |
| 77 | ABL1 | 0.18221748 |
| 78 | CSNK2A1 | 0.17384341 |
| 79 | PTK2B | 0.17341545 |
| 80 | CSNK2A2 | 0.17176183 |
| 81 | AURKB | 0.16201081 |
| 82 | PDK1 | 0.15840029 |
| 83 | MST1R | 0.15384893 |
| 84 | OBSCN | 0.14921641 |
| 85 | CAMK2D | 0.14311241 |
| 86 | TEC | 0.14307848 |
| 87 | PINK1 | 0.13065856 |
| 88 | ATR | 0.12581334 |
| 89 | CSNK1G1 | 0.12178876 |
| 90 | MAPK13 | 0.12017721 |
| 91 | PRKCQ | 0.11312416 |
| 92 | PRKCA | 0.11184315 |
| 93 | LIMK1 | 0.11141213 |
| 94 | MINK1 | 0.10608606 |
| 95 | CASK | 0.10473414 |
| 96 | PASK | 0.10304322 |
| 97 | TRPM7 | 0.09878568 |
| 98 | ROCK1 | 0.09799782 |
| 99 | CSNK1E | 0.09483516 |
| 100 | LRRK2 | 0.09034222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.83566283 |
| 2 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.68139236 |
| 3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.64900489 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.58805661 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 2.47063493 |
| 6 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.26435876 |
| 7 | Olfactory transduction_Homo sapiens_hsa04740 | 2.22342055 |
| 8 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.21389865 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.18761913 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.18441525 |
| 11 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.12332182 |
| 12 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.12184633 |
| 13 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.07334700 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.06854142 |
| 15 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.06503292 |
| 16 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.94248092 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.89029852 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.82773434 |
| 19 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.81718523 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.78605097 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.74571481 |
| 22 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.71742806 |
| 23 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.66133509 |
| 24 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.59149850 |
| 25 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.56201897 |
| 26 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.55364151 |
| 27 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.51979822 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.51384084 |
| 29 | Retinol metabolism_Homo sapiens_hsa00830 | 1.50421242 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.47683943 |
| 31 | Peroxisome_Homo sapiens_hsa04146 | 1.47647216 |
| 32 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.44956003 |
| 33 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.39012016 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.33815298 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.33075695 |
| 36 | Mismatch repair_Homo sapiens_hsa03430 | 1.26401335 |
| 37 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.24260516 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.21570885 |
| 39 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.21415070 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.19760644 |
| 41 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.15630439 |
| 42 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.12933482 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.10376463 |
| 44 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.09551438 |
| 45 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.06129608 |
| 46 | RNA transport_Homo sapiens_hsa03013 | 1.05466256 |
| 47 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.04743983 |
| 48 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.04600672 |
| 49 | RNA polymerase_Homo sapiens_hsa03020 | 1.03810007 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.01503859 |
| 51 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.01490376 |
| 52 | Lysine degradation_Homo sapiens_hsa00310 | 0.98442754 |
| 53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.96849844 |
| 54 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.95980130 |
| 55 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92729656 |
| 56 | ABC transporters_Homo sapiens_hsa02010 | 0.90380645 |
| 57 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.89759407 |
| 58 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.82140577 |
| 59 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.81926671 |
| 60 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.81654542 |
| 61 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.75731468 |
| 62 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.75597997 |
| 63 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74591707 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73131819 |
| 65 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.72996054 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.72817267 |
| 67 | Tight junction_Homo sapiens_hsa04530 | 0.71984067 |
| 68 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.71902149 |
| 69 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.70842665 |
| 70 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66598180 |
| 71 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.65084150 |
| 72 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.63266129 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63201635 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59790581 |
| 75 | Legionellosis_Homo sapiens_hsa05134 | 0.57868985 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57493077 |
| 77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.54439537 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54281676 |
| 79 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.53475781 |
| 80 | Huntingtons disease_Homo sapiens_hsa05016 | 0.53437905 |
| 81 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.53271621 |
| 82 | Purine metabolism_Homo sapiens_hsa00230 | 0.52854792 |
| 83 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.51582461 |
| 84 | Carbon metabolism_Homo sapiens_hsa01200 | 0.49756627 |
| 85 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.49585282 |
| 86 | Parkinsons disease_Homo sapiens_hsa05012 | 0.47619379 |
| 87 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44070155 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42923414 |
| 89 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41890460 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.41122010 |
| 91 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.40137969 |
| 92 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.39281134 |
| 93 | Mineral absorption_Homo sapiens_hsa04978 | 0.38069674 |
| 94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.35304898 |
| 95 | Melanogenesis_Homo sapiens_hsa04916 | 0.32459771 |
| 96 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31633923 |
| 97 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.30717771 |
| 98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.26334081 |
| 99 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.25252814 |
| 100 | Cell cycle_Homo sapiens_hsa04110 | 0.24603270 |

