Rank | Gene Set | Z-score |
---|---|---|
1 | heterochromatin organization (GO:0070828) | 4.11929732 |
2 | positive regulation of histone deacetylation (GO:0031065) | 4.08356263 |
3 | convergent extension (GO:0060026) | 4.03123547 |
4 | negative regulation of cell size (GO:0045792) | 3.98974651 |
5 | cell migration in hindbrain (GO:0021535) | 3.94882406 |
6 | pre-miRNA processing (GO:0031054) | 3.87724574 |
7 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.86416141 |
8 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.84801674 |
9 | histone arginine methylation (GO:0034969) | 3.60666100 |
10 | paraxial mesoderm development (GO:0048339) | 3.52615614 |
11 | positive regulation of synapse maturation (GO:0090129) | 3.41731398 |
12 | regulation of hippo signaling (GO:0035330) | 3.39354208 |
13 | regulation of translational fidelity (GO:0006450) | 3.38651226 |
14 | negative regulation of mRNA processing (GO:0050686) | 3.37000341 |
15 | peptidyl-arginine N-methylation (GO:0035246) | 3.35876304 |
16 | peptidyl-arginine methylation (GO:0018216) | 3.35876304 |
17 | L-serine metabolic process (GO:0006563) | 3.26998277 |
18 | maternal placenta development (GO:0001893) | 3.23259232 |
19 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.23159824 |
20 | mitochondrion transport along microtubule (GO:0047497) | 3.23159824 |
21 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.22686396 |
22 | NLS-bearing protein import into nucleus (GO:0006607) | 3.21352693 |
23 | mitotic chromosome condensation (GO:0007076) | 3.20674564 |
24 | negative regulation of mRNA metabolic process (GO:1903312) | 3.19919548 |
25 | establishment of apical/basal cell polarity (GO:0035089) | 3.19756784 |
26 | establishment of mitochondrion localization (GO:0051654) | 3.17882940 |
27 | adherens junction assembly (GO:0034333) | 3.14534530 |
28 | glial cell proliferation (GO:0014009) | 3.13897922 |
29 | layer formation in cerebral cortex (GO:0021819) | 3.11995800 |
30 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.11884055 |
31 | regulation of translational termination (GO:0006449) | 3.10978755 |
32 | regulation of ARF GTPase activity (GO:0032312) | 3.06298313 |
33 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.05775042 |
34 | DNA replication initiation (GO:0006270) | 3.03450321 |
35 | stress fiber assembly (GO:0043149) | 3.02469087 |
36 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 3.00893832 |
37 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.00880140 |
38 | apoptotic cell clearance (GO:0043277) | 3.00660268 |
39 | neural tube development (GO:0021915) | 2.98839819 |
40 | mRNA stabilization (GO:0048255) | 2.98511148 |
41 | RNA stabilization (GO:0043489) | 2.98511148 |
42 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.97825991 |
43 | nuclear pore complex assembly (GO:0051292) | 2.94901814 |
44 | DNA strand elongation (GO:0022616) | 2.93683438 |
45 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.93422036 |
46 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.93300036 |
47 | DNA topological change (GO:0006265) | 2.93261717 |
48 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.92899118 |
49 | gene silencing (GO:0016458) | 2.92431877 |
50 | positive regulation of nuclease activity (GO:0032075) | 2.91929587 |
51 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.91466858 |
52 | negative regulation of histone methylation (GO:0031061) | 2.90612155 |
53 | RNA localization (GO:0006403) | 2.89910593 |
54 | protein complex localization (GO:0031503) | 2.89497466 |
55 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.89385343 |
56 | DNA duplex unwinding (GO:0032508) | 2.88508272 |
57 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.87573297 |
58 | mannose metabolic process (GO:0006013) | 2.85513861 |
59 | semaphorin-plexin signaling pathway (GO:0071526) | 2.81606497 |
60 | chromatin silencing (GO:0006342) | 2.81085569 |
61 | polarized epithelial cell differentiation (GO:0030859) | 2.80630821 |
62 | gene silencing by RNA (GO:0031047) | 2.79870679 |
63 | mitotic sister chromatid segregation (GO:0000070) | 2.78196126 |
64 | establishment of integrated proviral latency (GO:0075713) | 2.77619507 |
65 | cell-cell junction maintenance (GO:0045217) | 2.77317936 |
66 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.75714826 |
67 | chromosome condensation (GO:0030261) | 2.75351255 |
68 | chromatin assembly (GO:0031497) | 2.74015365 |
69 | negative regulation of RNA splicing (GO:0033119) | 2.73036621 |
70 | embryonic foregut morphogenesis (GO:0048617) | 2.72395819 |
71 | nucleosome disassembly (GO:0006337) | 2.72355943 |
72 | protein-DNA complex disassembly (GO:0032986) | 2.72355943 |
73 | regulation of establishment of planar polarity (GO:0090175) | 2.71960620 |
74 | protein localization to endosome (GO:0036010) | 2.71118018 |
75 | negative regulation of fatty acid transport (GO:2000192) | 2.70731181 |
76 | Golgi transport vesicle coating (GO:0048200) | 2.70618448 |
77 | COPI coating of Golgi vesicle (GO:0048205) | 2.70618448 |
78 | focal adhesion assembly (GO:0048041) | 2.70080038 |
79 | cell-substrate adherens junction assembly (GO:0007045) | 2.70080038 |
80 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.69947772 |
81 | DNA geometric change (GO:0032392) | 2.69812808 |
82 | regulation of early endosome to late endosome transport (GO:2000641) | 2.68057741 |
83 | nuclear pore organization (GO:0006999) | 2.67580782 |
84 | receptor catabolic process (GO:0032801) | 2.67225105 |
85 | regulation of chromatin binding (GO:0035561) | 2.67083899 |
86 | sister chromatid segregation (GO:0000819) | 2.66749657 |
87 | positive regulation of RNA splicing (GO:0033120) | 2.66397842 |
88 | sodium ion export (GO:0071436) | 2.66171486 |
89 | protein heterotrimerization (GO:0070208) | 2.65262827 |
90 | positive regulation of protein deacetylation (GO:0090312) | 2.64611414 |
91 | rRNA transcription (GO:0009303) | 2.63147723 |
92 | establishment of monopolar cell polarity (GO:0061162) | 2.62648388 |
93 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.62648388 |
94 | regulation of nuclease activity (GO:0032069) | 2.61849423 |
95 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.61467616 |
96 | ATP-dependent chromatin remodeling (GO:0043044) | 2.60788301 |
97 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.59746930 |
98 | activation of Rac GTPase activity (GO:0032863) | 2.59697483 |
99 | cell-substrate junction assembly (GO:0007044) | 2.58163329 |
100 | apoptotic process involved in morphogenesis (GO:0060561) | 2.56301375 |
101 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.53124525 |
102 | signal complex assembly (GO:0007172) | 2.52185472 |
103 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.51749146 |
104 | histone H3-K9 demethylation (GO:0033169) | 2.51666616 |
105 | regulation of synapse maturation (GO:0090128) | 2.50652817 |
106 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.49546847 |
107 | locomotory exploration behavior (GO:0035641) | 2.49448296 |
108 | notochord development (GO:0030903) | 2.49231230 |
109 | DNA conformation change (GO:0071103) | 2.49039471 |
110 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.48175665 |
111 | activation of JUN kinase activity (GO:0007257) | 2.47672451 |
112 | sexual reproduction (GO:0019953) | 2.47381130 |
113 | histone H4 deacetylation (GO:0070933) | 2.46818281 |
114 | proline biosynthetic process (GO:0006561) | 2.46403083 |
115 | regulation of histone H3-K9 methylation (GO:0051570) | 2.45478173 |
116 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.45422667 |
117 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.44979331 |
118 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.44649730 |
119 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.44018295 |
120 | generation of neurons (GO:0048699) | 2.43185038 |
121 | macroautophagy (GO:0016236) | 2.42746114 |
122 | cortical actin cytoskeleton organization (GO:0030866) | 2.42253276 |
123 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.41269008 |
124 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.40704578 |
125 | negative regulation of organelle assembly (GO:1902116) | 2.40567722 |
126 | negative regulation of microtubule polymerization (GO:0031115) | 2.39451045 |
127 | stress granule assembly (GO:0034063) | 2.38362805 |
128 | mitotic G1/S transition checkpoint (GO:0044819) | 2.38220997 |
129 | establishment of nucleus localization (GO:0040023) | 2.38169192 |
130 | regulation of ARF protein signal transduction (GO:0032012) | 2.37955688 |
131 | negative regulation of telomerase activity (GO:0051974) | 2.37627749 |
132 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.36192004 |
133 | regulation of gene silencing by miRNA (GO:0060964) | 2.36192004 |
134 | regulation of gene silencing by RNA (GO:0060966) | 2.36192004 |
135 | gastrulation with mouth forming second (GO:0001702) | 2.35313131 |
136 | dosage compensation (GO:0007549) | 2.35167717 |
137 | synaptic vesicle endocytosis (GO:0048488) | 2.35102477 |
138 | mRNA polyadenylation (GO:0006378) | 2.34343238 |
139 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.33918437 |
140 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.33745527 |
141 | hippo signaling (GO:0035329) | 2.33205578 |
142 | * peptidyl-lysine dimethylation (GO:0018027) | 2.31476314 |
143 | histone H4-K5 acetylation (GO:0043981) | 2.30887627 |
144 | histone H4-K8 acetylation (GO:0043982) | 2.30887627 |
145 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.30767527 |
146 | morphogenesis of an endothelium (GO:0003159) | 2.30453058 |
147 | endothelial tube morphogenesis (GO:0061154) | 2.30453058 |
148 | response to epidermal growth factor (GO:0070849) | 2.30109306 |
149 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.29132821 |
150 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.29016718 |
151 | corticosteroid receptor signaling pathway (GO:0031958) | 2.28891400 |
152 | anatomical structure regression (GO:0060033) | 2.27711909 |
153 | regulation of RNA export from nucleus (GO:0046831) | 2.27604349 |
154 | negative regulation of cell fate specification (GO:0009996) | 2.27369824 |
155 | positive regulation of dendrite morphogenesis (GO:0050775) | 2.27295250 |
156 | cellular response to unfolded protein (GO:0034620) | 2.27011220 |
157 | peptidyl-threonine modification (GO:0018210) | 2.26765023 |
158 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.26743685 |
159 | postsynaptic membrane organization (GO:0001941) | 2.26645429 |
160 | chromatin remodeling (GO:0006338) | 2.26183583 |
161 | DNA unwinding involved in DNA replication (GO:0006268) | 2.26166017 |
162 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.26099961 |
163 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.26099961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.45433416 |
2 | MYC_22102868_ChIP-Seq_BL_Human | 3.42683836 |
3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.12852285 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.09682837 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.97088562 |
6 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.88952198 |
7 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.72809442 |
8 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.64568983 |
9 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.59415910 |
10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.55407413 |
11 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.42532632 |
12 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.36715097 |
13 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.36292495 |
14 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.35489553 |
15 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.33998519 |
16 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.31112707 |
17 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.16173177 |
18 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.14466959 |
19 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.14008708 |
20 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.13477378 |
21 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.07609330 |
22 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 2.05971444 |
23 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.05675168 |
24 | KDM2B_26808549_Chip-Seq_K562_Human | 2.03425357 |
25 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.93752950 |
26 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.90027428 |
27 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.88282075 |
28 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.86885645 |
29 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.82644966 |
30 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.77963164 |
31 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.76829498 |
32 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.75820291 |
33 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.73630581 |
34 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.73249243 |
35 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.71346166 |
36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.67596224 |
37 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.63884148 |
38 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.63811640 |
39 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.61474614 |
40 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.60546726 |
41 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.60328963 |
42 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.59869947 |
43 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.57207033 |
44 | UTX_26944678_Chip-Seq_JUKART_Human | 1.55658495 |
45 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.51627226 |
46 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.51545584 |
47 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.49588376 |
48 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.49477108 |
49 | P68_20966046_ChIP-Seq_HELA_Human | 1.47387036 |
50 | MAF_26560356_Chip-Seq_TH1_Human | 1.45866236 |
51 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.43345312 |
52 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.43200423 |
53 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.43114889 |
54 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.42115010 |
55 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.41787227 |
56 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.40219508 |
57 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.40087903 |
58 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.39871275 |
59 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.38507629 |
60 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.38348711 |
61 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.37556189 |
62 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.35098117 |
63 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.34156991 |
64 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.33989442 |
65 | ATF3_27146783_Chip-Seq_COLON_Human | 1.33517873 |
66 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.32862066 |
67 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.32323703 |
68 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.30402065 |
69 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.29700528 |
70 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.29549501 |
71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.28591213 |
72 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.27675454 |
73 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.27260502 |
74 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.25857165 |
75 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.25213251 |
76 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.24958966 |
77 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.24289722 |
78 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.22608974 |
79 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.20686175 |
80 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.20608653 |
81 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.20269519 |
82 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.20137698 |
83 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.19943848 |
84 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.19901737 |
85 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.19462656 |
86 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.17965202 |
87 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.17204500 |
88 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.16842350 |
89 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.16442670 |
90 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.16246475 |
91 | * SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.16009051 |
92 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.15684769 |
93 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.14331850 |
94 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.13509232 |
95 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.10345021 |
96 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.09976815 |
97 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.09586605 |
98 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.09389125 |
99 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.09120436 |
100 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.08479034 |
101 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.08370791 |
102 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.08264118 |
103 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.07866488 |
104 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.07631842 |
105 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.06905023 |
106 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.06862326 |
107 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.06267288 |
108 | * ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.06260269 |
109 | SPI1_23127762_ChIP-Seq_K562_Human | 1.05855051 |
110 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.05750320 |
111 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.05746267 |
112 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.05071235 |
113 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.05050617 |
114 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.04940235 |
115 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.04723367 |
116 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.04636717 |
117 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.03214500 |
118 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.03170458 |
119 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.02760914 |
120 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.02739710 |
121 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.02549170 |
122 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 1.02458713 |
123 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01407780 |
124 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.00858384 |
125 | MAF_26560356_Chip-Seq_TH2_Human | 1.00327692 |
126 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00294048 |
127 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.99522914 |
128 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.97518855 |
129 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96776349 |
130 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.96720332 |
131 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.96012725 |
132 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.95739008 |
133 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.94958485 |
134 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.93585134 |
135 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.93405837 |
136 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.92703501 |
137 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.90819148 |
138 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.89605884 |
139 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.89292887 |
140 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.89237761 |
141 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88928948 |
142 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.87439921 |
143 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.87014784 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 5.10290648 |
2 | MP0005076_abnormal_cell_differentiation | 3.41660482 |
3 | MP0010234_abnormal_vibrissa_follicle | 3.33908491 |
4 | MP0003283_abnormal_digestive_organ | 2.91500223 |
5 | MP0010352_gastrointestinal_tract_polyps | 2.84888123 |
6 | MP0003300_gastrointestinal_ulcer | 2.73696550 |
7 | MP0000569_abnormal_digit_pigmentation | 2.63801780 |
8 | MP0000566_synostosis | 2.58884582 |
9 | MP0009278_abnormal_bone_marrow | 2.54360864 |
10 | MP0008961_abnormal_basal_metabolism | 2.51119830 |
11 | MP0005623_abnormal_meninges_morphology | 2.40855952 |
12 | MP0001849_ear_inflammation | 2.23235734 |
13 | MP0008438_abnormal_cutaneous_collagen | 2.22419516 |
14 | MP0002249_abnormal_larynx_morphology | 2.18280913 |
15 | MP0003693_abnormal_embryo_hatching | 2.16814657 |
16 | MP0004858_abnormal_nervous_system | 2.12594686 |
17 | MP0003303_peritoneal_inflammation | 2.10822992 |
18 | MP0000537_abnormal_urethra_morphology | 2.10653063 |
19 | MP0010094_abnormal_chromosome_stability | 2.06982959 |
20 | MP0010307_abnormal_tumor_latency | 2.04788727 |
21 | MP0004859_abnormal_synaptic_plasticity | 1.99560380 |
22 | MP0006292_abnormal_olfactory_placode | 1.90376363 |
23 | MP0003566_abnormal_cell_adhesion | 1.82152858 |
24 | MP0000778_abnormal_nervous_system | 1.81039353 |
25 | MP0000733_abnormal_muscle_development | 1.75141029 |
26 | MP0002877_abnormal_melanocyte_morpholog | 1.67828293 |
27 | MP0005410_abnormal_fertilization | 1.67756945 |
28 | MP0004185_abnormal_adipocyte_glucose | 1.65991698 |
29 | MP0008932_abnormal_embryonic_tissue | 1.64033731 |
30 | MP0004957_abnormal_blastocyst_morpholog | 1.63485077 |
31 | MP0004197_abnormal_fetal_growth/weight/ | 1.62322045 |
32 | MP0003122_maternal_imprinting | 1.60373405 |
33 | MP0003115_abnormal_respiratory_system | 1.60209596 |
34 | MP0002653_abnormal_ependyma_morphology | 1.57105569 |
35 | MP0003123_paternal_imprinting | 1.55118520 |
36 | MP0009780_abnormal_chondrocyte_physiolo | 1.54839289 |
37 | MP0004270_analgesia | 1.54404684 |
38 | MP0002909_abnormal_adrenal_gland | 1.54399407 |
39 | MP0000049_abnormal_middle_ear | 1.52121950 |
40 | MP0004233_abnormal_muscle_weight | 1.48752068 |
41 | MP0005423_abnormal_somatic_nervous | 1.46565758 |
42 | MP0003136_yellow_coat_color | 1.43648203 |
43 | MP0003938_abnormal_ear_development | 1.42230822 |
44 | MP0003635_abnormal_synaptic_transmissio | 1.41111854 |
45 | MP0003172_abnormal_lysosome_physiology | 1.40229471 |
46 | MP0003045_fibrosis | 1.39848223 |
47 | MP0003091_abnormal_cell_migration | 1.38350345 |
48 | MP0001293_anophthalmia | 1.38131870 |
49 | MP0003119_abnormal_digestive_system | 1.35662952 |
50 | MP0002084_abnormal_developmental_patter | 1.34840803 |
51 | MP0001299_abnormal_eye_distance/ | 1.33641562 |
52 | * MP0001730_embryonic_growth_arrest | 1.33451647 |
53 | MP0004808_abnormal_hematopoietic_stem | 1.30848961 |
54 | MP0000003_abnormal_adipose_tissue | 1.29895056 |
55 | MP0005375_adipose_tissue_phenotype | 1.28783125 |
56 | MP0002152_abnormal_brain_morphology | 1.27452673 |
57 | MP0005499_abnormal_olfactory_system | 1.27254568 |
58 | MP0005394_taste/olfaction_phenotype | 1.27254568 |
59 | MP0002116_abnormal_craniofacial_bone | 1.26347482 |
60 | MP0002822_catalepsy | 1.24327381 |
61 | MP0005666_abnormal_adipose_tissue | 1.24299245 |
62 | MP0004133_heterotaxia | 1.24209618 |
63 | MP0000534_abnormal_ureter_morphology | 1.23944618 |
64 | MP0000955_abnormal_spinal_cord | 1.22895302 |
65 | MP0003937_abnormal_limbs/digits/tail_de | 1.22287500 |
66 | MP0001348_abnormal_lacrimal_gland | 1.19755755 |
67 | MP0000428_abnormal_craniofacial_morphol | 1.18221446 |
68 | MP0003111_abnormal_nucleus_morphology | 1.18085792 |
69 | MP0002089_abnormal_postnatal_growth/wei | 1.17843042 |
70 | MP0001958_emphysema | 1.17549714 |
71 | MP0008877_abnormal_DNA_methylation | 1.17537171 |
72 | MP0009672_abnormal_birth_weight | 1.17156776 |
73 | MP0005023_abnormal_wound_healing | 1.16653962 |
74 | * MP0002086_abnormal_extraembryonic_tissu | 1.15529963 |
75 | MP0005670_abnormal_white_adipose | 1.14366934 |
76 | MP0004272_abnormal_basement_membrane | 1.13969536 |
77 | * MP0002063_abnormal_learning/memory/cond | 1.13382774 |
78 | MP0000678_abnormal_parathyroid_gland | 1.11566278 |
79 | MP0003880_abnormal_central_pattern | 1.09395086 |
80 | MP0005275_abnormal_skin_tensile | 1.09206585 |
81 | MP0009053_abnormal_anal_canal | 1.07345934 |
82 | MP0001672_abnormal_embryogenesis/_devel | 1.05424123 |
83 | MP0005380_embryogenesis_phenotype | 1.05424123 |
84 | MP0003878_abnormal_ear_physiology | 1.04469989 |
85 | MP0005377_hearing/vestibular/ear_phenot | 1.04469989 |
86 | * MP0002085_abnormal_embryonic_tissue | 1.03228122 |
87 | MP0002184_abnormal_innervation | 1.03056555 |
88 | * MP0004811_abnormal_neuron_physiology | 1.02293436 |
89 | MP0001915_intracranial_hemorrhage | 1.02291084 |
90 | MP0001286_abnormal_eye_development | 1.01998916 |
91 | MP0003984_embryonic_growth_retardation | 1.01687979 |
92 | MP0002088_abnormal_embryonic_growth/wei | 1.01621221 |
93 | MP0002081_perinatal_lethality | 1.01455619 |
94 | MP0000432_abnormal_head_morphology | 0.99928206 |
95 | MP0009703_decreased_birth_body | 0.99760859 |
96 | MP0000350_abnormal_cell_proliferation | 0.99687872 |
97 | MP0003890_abnormal_embryonic-extraembry | 0.99684811 |
98 | MP0002233_abnormal_nose_morphology | 0.98902007 |
99 | MP0002234_abnormal_pharynx_morphology | 0.97324836 |
100 | MP0002896_abnormal_bone_mineralization | 0.96920871 |
101 | * MP0002080_prenatal_lethality | 0.96034848 |
102 | MP0008770_decreased_survivor_rate | 0.95711921 |
103 | MP0003315_abnormal_perineum_morphology | 0.95351231 |
104 | MP0005397_hematopoietic_system_phenotyp | 0.94497775 |
105 | MP0001545_abnormal_hematopoietic_system | 0.94497775 |
106 | MP0001346_abnormal_lacrimal_gland | 0.94344064 |
107 | MP0006054_spinal_hemorrhage | 0.94126557 |
108 | MP0002882_abnormal_neuron_morphology | 0.93950958 |
109 | MP0004130_abnormal_muscle_cell | 0.93823968 |
110 | MP0002925_abnormal_cardiovascular_devel | 0.93603541 |
111 | MP0005167_abnormal_blood-brain_barrier | 0.93074321 |
112 | MP0002734_abnormal_mechanical_nocicepti | 0.90942130 |
113 | MP0002114_abnormal_axial_skeleton | 0.88422031 |
114 | MP0002254_reproductive_system_inflammat | 0.88284585 |
115 | MP0003755_abnormal_palate_morphology | 0.87535771 |
116 | * MP0001697_abnormal_embryo_size | 0.86967128 |
117 | MP0000631_abnormal_neuroendocrine_gland | 0.86002401 |
118 | MP0002697_abnormal_eye_size | 0.84076843 |
119 | MP0002092_abnormal_eye_morphology | 0.82954554 |
120 | MP0010030_abnormal_orbit_morphology | 0.82798900 |
121 | MP0002735_abnormal_chemical_nociception | 0.81985858 |
122 | MP0001502_abnormal_circadian_rhythm | 0.80945323 |
123 | MP0003698_abnormal_male_reproductive | 0.80663748 |
124 | MP0002557_abnormal_social/conspecific_i | 0.80264503 |
125 | MP0003942_abnormal_urinary_system | 0.80216513 |
126 | MP0005171_absent_coat_pigmentation | 0.77720976 |
127 | MP0002064_seizures | 0.77662891 |
128 | MP0003935_abnormal_craniofacial_develop | 0.77629289 |
129 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77410056 |
130 | MP0008058_abnormal_DNA_repair | 0.77151757 |
131 | MP0002938_white_spotting | 0.76941004 |
132 | MP0001929_abnormal_gametogenesis | 0.76724358 |
133 | MP0002751_abnormal_autonomic_nervous | 0.76706434 |
134 | MP0004264_abnormal_extraembryonic_tissu | 0.76111355 |
135 | MP0010630_abnormal_cardiac_muscle | 0.75931362 |
136 | MP0002932_abnormal_joint_morphology | 0.75786794 |
137 | MP0001340_abnormal_eyelid_morphology | 0.75705612 |
138 | MP0000013_abnormal_adipose_tissue | 0.75305996 |
139 | MP0005187_abnormal_penis_morphology | 0.74622025 |
140 | MP0000371_diluted_coat_color | 0.73816690 |
141 | MP0004947_skin_inflammation | 0.73213624 |
142 | MP0004885_abnormal_endolymph | 0.72048878 |
143 | MP0003279_aneurysm | 0.71292233 |
144 | MP0005257_abnormal_intraocular_pressure | 0.71008427 |
145 | MP0009840_abnormal_foam_cell | 0.68095655 |
146 | MP0000266_abnormal_heart_morphology | 0.67687468 |
147 | MP0004087_abnormal_muscle_fiber | 0.67437647 |
148 | * MP0003861_abnormal_nervous_system | 0.66896216 |
149 | MP0002928_abnormal_bile_duct | 0.66438751 |
150 | MP0001784_abnormal_fluid_regulation | 0.62441423 |
151 | MP0004510_myositis | 0.61855036 |
152 | MP0000751_myopathy | 0.61811816 |
153 | MP0002111_abnormal_tail_morphology | 0.61708757 |
154 | MP0003385_abnormal_body_wall | 0.60990369 |
155 | MP0001145_abnormal_male_reproductive | 0.60957529 |
156 | MP0003077_abnormal_cell_cycle | 0.59707233 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 4.31953947 |
2 | Cerebral aneurysm (HP:0004944) | 4.01264103 |
3 | Abnormality of the lower motor neuron (HP:0002366) | 3.35305564 |
4 | Renovascular hypertension (HP:0100817) | 3.25134488 |
5 | Distal upper limb amyotrophy (HP:0007149) | 3.24812325 |
6 | Upper limb amyotrophy (HP:0009129) | 3.24812325 |
7 | Elfin facies (HP:0004428) | 3.23074485 |
8 | Hand muscle atrophy (HP:0009130) | 3.20234531 |
9 | High anterior hairline (HP:0009890) | 3.13533354 |
10 | Insomnia (HP:0100785) | 3.08154804 |
11 | Shallow orbits (HP:0000586) | 3.06343866 |
12 | Renal duplication (HP:0000075) | 3.03829977 |
13 | Bronchomalacia (HP:0002780) | 2.90537455 |
14 | Protrusio acetabuli (HP:0003179) | 2.88120948 |
15 | Bladder diverticulum (HP:0000015) | 2.77622284 |
16 | Overriding aorta (HP:0002623) | 2.71420132 |
17 | Bowel diverticulosis (HP:0005222) | 2.71360663 |
18 | Trigonocephaly (HP:0000243) | 2.69033086 |
19 | Ankle contracture (HP:0006466) | 2.68334775 |
20 | Pointed chin (HP:0000307) | 2.62165281 |
21 | Broad distal phalanx of finger (HP:0009836) | 2.60019783 |
22 | Short 4th metacarpal (HP:0010044) | 2.54640217 |
23 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.54640217 |
24 | Macroorchidism (HP:0000053) | 2.49939533 |
25 | Obstructive sleep apnea (HP:0002870) | 2.46071068 |
26 | Astrocytoma (HP:0009592) | 2.38902217 |
27 | Abnormality of the astrocytes (HP:0100707) | 2.38902217 |
28 | Abnormality of the aortic arch (HP:0012303) | 2.36315310 |
29 | Flat cornea (HP:0007720) | 2.35674636 |
30 | Genu recurvatum (HP:0002816) | 2.34329881 |
31 | Subacute progressive viral hepatitis (HP:0006572) | 2.34219945 |
32 | Ependymoma (HP:0002888) | 2.32481681 |
33 | Enlarged penis (HP:0000040) | 2.31643496 |
34 | Mitral valve prolapse (HP:0001634) | 2.31365822 |
35 | Lymphangioma (HP:0100764) | 2.29953316 |
36 | Choanal stenosis (HP:0000452) | 2.28437460 |
37 | Neoplasm of the heart (HP:0100544) | 2.28070325 |
38 | Morphological abnormality of the inner ear (HP:0011390) | 2.25033403 |
39 | Ulnar bowing (HP:0003031) | 2.24328644 |
40 | Aneurysm (HP:0002617) | 2.23201715 |
41 | Spina bifida occulta (HP:0003298) | 2.19085475 |
42 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.18931604 |
43 | Absent epiphyses (HP:0010577) | 2.18931604 |
44 | Generalized hypotonia (HP:0001290) | 2.17626751 |
45 | Abnormality of the 4th metacarpal (HP:0010012) | 2.15716053 |
46 | Heterotopia (HP:0002282) | 2.15654961 |
47 | Abnormality of cochlea (HP:0000375) | 2.15203287 |
48 | Hallux valgus (HP:0001822) | 2.13295640 |
49 | Ankyloglossia (HP:0010296) | 2.12380879 |
50 | Increased nuchal translucency (HP:0010880) | 2.11819645 |
51 | Deviation of the hallux (HP:0010051) | 2.11418321 |
52 | Dilatation of the ascending aorta (HP:0005111) | 2.10816710 |
53 | Vitreoretinal degeneration (HP:0000655) | 2.10481632 |
54 | Deep palmar crease (HP:0006191) | 2.10243446 |
55 | Turricephaly (HP:0000262) | 2.08257970 |
56 | Disproportionate tall stature (HP:0001519) | 2.07035588 |
57 | Thin bony cortex (HP:0002753) | 2.04315723 |
58 | Broad phalanges of the hand (HP:0009768) | 2.04032068 |
59 | Hepatoblastoma (HP:0002884) | 2.01493696 |
60 | Abnormality of oral frenula (HP:0000190) | 1.98724252 |
61 | Long palpebral fissure (HP:0000637) | 1.98274306 |
62 | Nasal polyposis (HP:0100582) | 1.96687927 |
63 | Male infertility (HP:0003251) | 1.96032457 |
64 | Rectal prolapse (HP:0002035) | 1.95683345 |
65 | Broad finger (HP:0001500) | 1.95235207 |
66 | Broad metatarsal (HP:0001783) | 1.93853058 |
67 | Precocious puberty (HP:0000826) | 1.92920237 |
68 | Achilles tendon contracture (HP:0001771) | 1.91685525 |
69 | Fibroma (HP:0010614) | 1.91281917 |
70 | Cortical dysplasia (HP:0002539) | 1.90785363 |
71 | Patellar aplasia (HP:0006443) | 1.89827697 |
72 | Long toe (HP:0010511) | 1.89318016 |
73 | Pseudobulbar signs (HP:0002200) | 1.86834211 |
74 | Resting tremor (HP:0002322) | 1.86390605 |
75 | Premature rupture of membranes (HP:0001788) | 1.85900779 |
76 | Patellar dislocation (HP:0002999) | 1.84615802 |
77 | Fibrous tissue neoplasm (HP:0012316) | 1.84520414 |
78 | Myokymia (HP:0002411) | 1.84453555 |
79 | Tracheomalacia (HP:0002779) | 1.84272654 |
80 | Aortic aneurysm (HP:0004942) | 1.84109043 |
81 | Peripheral hypomyelination (HP:0007182) | 1.84083846 |
82 | Selective tooth agenesis (HP:0001592) | 1.83230849 |
83 | Coronal craniosynostosis (HP:0004440) | 1.82370023 |
84 | Abnormality of the fingertips (HP:0001211) | 1.81630678 |
85 | Buphthalmos (HP:0000557) | 1.80507890 |
86 | Back pain (HP:0003418) | 1.80416638 |
87 | Broad palm (HP:0001169) | 1.79437493 |
88 | Broad face (HP:0000283) | 1.78794370 |
89 | Megalocornea (HP:0000485) | 1.77290979 |
90 | High pitched voice (HP:0001620) | 1.76050313 |
91 | Abnormality of the Achilles tendon (HP:0005109) | 1.75917597 |
92 | Obsessive-compulsive behavior (HP:0000722) | 1.75881624 |
93 | Germ cell neoplasia (HP:0100728) | 1.75582959 |
94 | Abnormality of the nasal mucosa (HP:0000433) | 1.75001686 |
95 | Hemiplegia (HP:0002301) | 1.74951568 |
96 | Skull defect (HP:0001362) | 1.74905707 |
97 | Aplasia involving bones of the extremities (HP:0009825) | 1.74473553 |
98 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.74473553 |
99 | Aplasia of the phalanges of the hand (HP:0009802) | 1.74473553 |
100 | Attention deficit hyperactivity disorder (HP:0007018) | 1.74176632 |
101 | Difficulty climbing stairs (HP:0003551) | 1.73681327 |
102 | Glossoptosis (HP:0000162) | 1.73118049 |
103 | Annular pancreas (HP:0001734) | 1.72738856 |
104 | Striae distensae (HP:0001065) | 1.72281531 |
105 | Increased density of long bones (HP:0006392) | 1.71438411 |
106 | Biconcave vertebral bodies (HP:0004586) | 1.70637858 |
107 | Abnormality of the diencephalon (HP:0010662) | 1.70294440 |
108 | Asymmetry of the thorax (HP:0001555) | 1.70029999 |
109 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.69341063 |
110 | Thin ribs (HP:0000883) | 1.69099068 |
111 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.68658293 |
112 | Impulsivity (HP:0100710) | 1.68642014 |
113 | Truncus arteriosus (HP:0001660) | 1.67971236 |
114 | Partial duplication of thumb phalanx (HP:0009944) | 1.67721465 |
115 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.67286908 |
116 | Abnormal number of incisors (HP:0011064) | 1.66444495 |
117 | Hypercortisolism (HP:0001578) | 1.66276106 |
118 | Dysmetric saccades (HP:0000641) | 1.65708018 |
119 | Broad phalanx (HP:0006009) | 1.65579967 |
120 | Increased connective tissue (HP:0009025) | 1.65304435 |
121 | Breast hypoplasia (HP:0003187) | 1.65160315 |
122 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.64767873 |
123 | Preauricular skin tag (HP:0000384) | 1.64235391 |
124 | Arnold-Chiari malformation (HP:0002308) | 1.63644744 |
125 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.62767053 |
126 | Short phalanx of the thumb (HP:0009660) | 1.62360742 |
127 | Atresia of the external auditory canal (HP:0000413) | 1.61720198 |
128 | Atrophic scars (HP:0001075) | 1.61518506 |
129 | Cervical subluxation (HP:0003308) | 1.61391367 |
130 | Midface retrusion (HP:0011800) | 1.61134478 |
131 | Gastrointestinal carcinoma (HP:0002672) | 1.61096293 |
132 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.61096293 |
133 | Broad thumb (HP:0011304) | 1.60879792 |
134 | Apathy (HP:0000741) | 1.59065565 |
135 | Vertebral arch anomaly (HP:0008438) | 1.58825333 |
136 | Cutaneous melanoma (HP:0012056) | 1.58572947 |
137 | Absent frontal sinuses (HP:0002688) | 1.58221858 |
138 | Global brain atrophy (HP:0002283) | 1.57985262 |
139 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.57756777 |
140 | Abnormally folded helix (HP:0008544) | 1.57065951 |
141 | Abnormality of the intervertebral disk (HP:0005108) | 1.56757224 |
142 | Hypopigmentation of the fundus (HP:0007894) | 1.56698203 |
143 | Polygenic inheritance (HP:0010982) | 1.55765364 |
144 | Glioma (HP:0009733) | 1.55703062 |
145 | Radial bowing (HP:0002986) | 1.55677825 |
146 | Missing ribs (HP:0000921) | 1.55581472 |
147 | Broad long bones (HP:0005622) | 1.54909870 |
148 | Neoplasm of the adrenal cortex (HP:0100641) | 1.54706476 |
149 | Difficulty running (HP:0009046) | 1.54332354 |
150 | Metaphyseal cupping (HP:0003021) | 1.54294386 |
151 | Milia (HP:0001056) | 1.54284364 |
152 | Bowing of the arm (HP:0006488) | 1.53655496 |
153 | Bowed forearm bones (HP:0003956) | 1.53655496 |
154 | Broad forehead (HP:0000337) | 1.53330522 |
155 | Adducted thumb (HP:0001181) | 1.53003100 |
156 | Proximal placement of thumb (HP:0009623) | 1.52378243 |
157 | Bowel incontinence (HP:0002607) | 1.52361237 |
158 | Spastic diplegia (HP:0001264) | 1.51188477 |
159 | Urethral obstruction (HP:0000796) | 1.51114667 |
160 | Skin tags (HP:0010609) | 1.50714184 |
161 | Premature skin wrinkling (HP:0100678) | 1.50483606 |
162 | Diminished motivation (HP:0000745) | 1.48123390 |
163 | Frequent falls (HP:0002359) | 1.47567606 |
164 | Spinal muscular atrophy (HP:0007269) | 1.46763551 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 5.00571644 |
2 | SMG1 | 3.99682489 |
3 | EEF2K | 3.95551246 |
4 | PKN2 | 3.95073813 |
5 | MAP3K10 | 3.26887567 |
6 | PRKD3 | 2.87373129 |
7 | ICK | 2.77440566 |
8 | CDK12 | 2.51799916 |
9 | RIPK1 | 2.41408429 |
10 | PDGFRA | 2.16866346 |
11 | PTK6 | 2.09926486 |
12 | ERN1 | 1.89312655 |
13 | TYRO3 | 1.82363249 |
14 | SCYL2 | 1.68335185 |
15 | NEK2 | 1.62349166 |
16 | ALK | 1.62123356 |
17 | TTN | 1.58124712 |
18 | BMX | 1.50041648 |
19 | SIK2 | 1.49758499 |
20 | EPHA4 | 1.46213367 |
21 | MAP3K9 | 1.44678954 |
22 | KSR2 | 1.40046066 |
23 | DDR2 | 1.39732156 |
24 | TTK | 1.39324810 |
25 | SIK1 | 1.36112440 |
26 | VRK2 | 1.34387403 |
27 | CDK19 | 1.33456524 |
28 | TESK1 | 1.31561251 |
29 | CAMKK1 | 1.29204647 |
30 | CAMK1G | 1.25819621 |
31 | BUB1 | 1.22995860 |
32 | TAOK1 | 1.20494152 |
33 | PAK4 | 1.19033033 |
34 | * MTOR | 1.18846709 |
35 | UHMK1 | 1.18584195 |
36 | CAMK1D | 1.17502744 |
37 | LRRK2 | 1.15191876 |
38 | PAK6 | 1.14108543 |
39 | CDK7 | 1.12998276 |
40 | DAPK2 | 1.08160012 |
41 | DYRK2 | 1.05155548 |
42 | MARK1 | 1.04096300 |
43 | TSSK6 | 1.01886934 |
44 | STK38 | 1.01824041 |
45 | PAK2 | 0.97944216 |
46 | RET | 0.97194548 |
47 | CHEK2 | 0.97005386 |
48 | PASK | 0.94214420 |
49 | MAP4K1 | 0.93190047 |
50 | CDK4 | 0.92120608 |
51 | PRPF4B | 0.91246607 |
52 | ATR | 0.90737564 |
53 | SRPK1 | 0.89181309 |
54 | CDK6 | 0.88270240 |
55 | TAF1 | 0.88130240 |
56 | PTK2 | 0.86656403 |
57 | PRKCH | 0.86369437 |
58 | LATS2 | 0.86045388 |
59 | DYRK1B | 0.85077674 |
60 | PDGFRB | 0.83817096 |
61 | LATS1 | 0.82877169 |
62 | PDK3 | 0.81255920 |
63 | PDK4 | 0.81255920 |
64 | FGFR4 | 0.80760405 |
65 | BRSK1 | 0.80245252 |
66 | CDC7 | 0.77006520 |
67 | MAP3K7 | 0.74965737 |
68 | BRAF | 0.73720360 |
69 | LMTK2 | 0.73464097 |
70 | CDK11A | 0.73030500 |
71 | CDK1 | 0.72724601 |
72 | MAP3K2 | 0.72411452 |
73 | AURKA | 0.72328033 |
74 | NEK1 | 0.72203331 |
75 | GRK6 | 0.71889799 |
76 | MKNK1 | 0.71079917 |
77 | MAP3K8 | 0.65590676 |
78 | BRD4 | 0.65060899 |
79 | CDK15 | 0.64701397 |
80 | NTRK3 | 0.63934662 |
81 | CDC42BPA | 0.62634397 |
82 | RPS6KA2 | 0.62081828 |
83 | FGFR1 | 0.60410967 |
84 | DMPK | 0.60343939 |
85 | RPS6KB2 | 0.58627875 |
86 | CDK18 | 0.58569038 |
87 | RPS6KL1 | 0.58144503 |
88 | RPS6KC1 | 0.58144503 |
89 | NTRK1 | 0.58055009 |
90 | NME2 | 0.58017267 |
91 | KSR1 | 0.57074603 |
92 | PRKD2 | 0.55953577 |
93 | PDK1 | 0.55766403 |
94 | MARK2 | 0.55641329 |
95 | GSK3B | 0.55502823 |
96 | MAPK10 | 0.52129267 |
97 | MINK1 | 0.49772286 |
98 | STK11 | 0.49491875 |
99 | EPHA2 | 0.48451083 |
100 | PLK1 | 0.48400381 |
101 | CDK14 | 0.47942770 |
102 | NTRK2 | 0.47498293 |
103 | HCK | 0.47463531 |
104 | FLT3 | 0.47122858 |
105 | PTK2B | 0.47105775 |
106 | RPS6KA1 | 0.47086082 |
107 | FGFR3 | 0.46891268 |
108 | STK10 | 0.46544537 |
109 | FGFR2 | 0.46215700 |
110 | AURKB | 0.45884179 |
111 | CSNK1E | 0.45538683 |
112 | NME1 | 0.44691774 |
113 | EPHB1 | 0.44201362 |
114 | CHEK1 | 0.43807054 |
115 | STK3 | 0.43754183 |
116 | RPS6KA6 | 0.43649312 |
117 | PDPK1 | 0.43426048 |
118 | MAPK14 | 0.43095160 |
119 | AKT1 | 0.42624227 |
120 | HIPK2 | 0.42332845 |
121 | TESK2 | 0.41368709 |
122 | TNK2 | 0.40968260 |
123 | ATM | 0.40365574 |
124 | CDK9 | 0.40152166 |
125 | CDK2 | 0.39266653 |
126 | JAK1 | 0.38982904 |
127 | DAPK1 | 0.38334499 |
128 | CSF1R | 0.38044847 |
129 | JAK2 | 0.37386461 |
130 | SGK3 | 0.37049016 |
131 | MAP3K1 | 0.36407627 |
132 | DAPK3 | 0.35980678 |
133 | MAPK9 | 0.35571651 |
134 | CDK5 | 0.35524323 |
135 | PRKD1 | 0.34816767 |
136 | RPS6KA4 | 0.34678006 |
137 | MAP2K2 | 0.34641765 |
138 | ILK | 0.33632691 |
139 | MAPK15 | 0.33318507 |
140 | ERBB2 | 0.33034215 |
141 | MAPK8 | 0.32669093 |
142 | EPHB2 | 0.30966747 |
143 | AKT2 | 0.29702868 |
144 | CSNK1D | 0.29115682 |
145 | SRC | 0.29038090 |
146 | PRKDC | 0.28296770 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 2.98131720 |
2 | Base excision repair_Homo sapiens_hsa03410 | 2.42415283 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.06926145 |
4 | Spliceosome_Homo sapiens_hsa03040 | 2.00495683 |
5 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.96596191 |
6 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.89779539 |
7 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.83730802 |
8 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.81407029 |
9 | Mismatch repair_Homo sapiens_hsa03430 | 1.67548792 |
10 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.65387453 |
11 | Glioma_Homo sapiens_hsa05214 | 1.63366871 |
12 | Cell cycle_Homo sapiens_hsa04110 | 1.59881008 |
13 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.55209825 |
14 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.51813798 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.50872238 |
16 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.45948689 |
17 | Endometrial cancer_Homo sapiens_hsa05213 | 1.42492815 |
18 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.40097509 |
19 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.39403406 |
20 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.39215298 |
21 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.38234956 |
22 | RNA transport_Homo sapiens_hsa03013 | 1.38191164 |
23 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.36681249 |
24 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.36448921 |
25 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.34827405 |
26 | Axon guidance_Homo sapiens_hsa04360 | 1.34062552 |
27 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.32488260 |
28 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.28958036 |
29 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.25850908 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.24201643 |
31 | Focal adhesion_Homo sapiens_hsa04510 | 1.24044271 |
32 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.22735484 |
33 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.19253809 |
34 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.17036850 |
35 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.16993294 |
36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.14459029 |
37 | Insulin resistance_Homo sapiens_hsa04931 | 1.13753673 |
38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.11863383 |
39 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.09662530 |
40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.09646432 |
41 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.09230152 |
42 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.08884117 |
43 | Sulfur relay system_Homo sapiens_hsa04122 | 1.08229097 |
44 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.05588480 |
45 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.05340204 |
46 | Colorectal cancer_Homo sapiens_hsa05210 | 1.04758830 |
47 | * Lysine degradation_Homo sapiens_hsa00310 | 1.03318683 |
48 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.02710327 |
49 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.01764145 |
50 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.00470525 |
51 | Adherens junction_Homo sapiens_hsa04520 | 0.99288139 |
52 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.97431048 |
53 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.96199678 |
54 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.95895382 |
55 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.95748080 |
56 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.94966555 |
57 | Amoebiasis_Homo sapiens_hsa05146 | 0.94900333 |
58 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.94071783 |
59 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.93256246 |
60 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.93131928 |
61 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.92628291 |
62 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92340212 |
63 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.92273693 |
64 | Long-term potentiation_Homo sapiens_hsa04720 | 0.91960201 |
65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.89877375 |
66 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.89794514 |
67 | * Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.89504704 |
68 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.88373987 |
69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.88269394 |
70 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.87647207 |
71 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.87408352 |
72 | Alcoholism_Homo sapiens_hsa05034 | 0.87182101 |
73 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.86115238 |
74 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.85419703 |
75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.84770551 |
76 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.84257695 |
77 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.83051159 |
78 | Endocytosis_Homo sapiens_hsa04144 | 0.82151516 |
79 | HTLV-I infection_Homo sapiens_hsa05166 | 0.80826719 |
80 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.80165433 |
81 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.80115857 |
82 | Gap junction_Homo sapiens_hsa04540 | 0.80073271 |
83 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.79049388 |
84 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.78275329 |
85 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.78063455 |
86 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.77991499 |
87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.77529422 |
88 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77348160 |
89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.77040724 |
90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.76524859 |
91 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.76200322 |
92 | Thyroid cancer_Homo sapiens_hsa05216 | 0.75821151 |
93 | Platelet activation_Homo sapiens_hsa04611 | 0.75747153 |
94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.75288719 |
95 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.75198762 |
96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.73889151 |
97 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.73516295 |
98 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.73331178 |
99 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.72975376 |
100 | Melanogenesis_Homo sapiens_hsa04916 | 0.72247158 |
101 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.72167307 |
102 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.71697773 |
103 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.71357843 |
104 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70346382 |
105 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.69787590 |
106 | Bile secretion_Homo sapiens_hsa04976 | 0.69190423 |
107 | Cocaine addiction_Homo sapiens_hsa05030 | 0.68904191 |
108 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.68827574 |
109 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.68745051 |
110 | Insulin secretion_Homo sapiens_hsa04911 | 0.67905300 |
111 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.67806973 |
112 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.67514327 |
113 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.67250710 |
114 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.66918265 |
115 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.66665867 |
116 | Prostate cancer_Homo sapiens_hsa05215 | 0.66459994 |
117 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.66382950 |
118 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.62975700 |
119 | Tight junction_Homo sapiens_hsa04530 | 0.61856069 |
120 | Homologous recombination_Homo sapiens_hsa03440 | 0.61713791 |
121 | Renin secretion_Homo sapiens_hsa04924 | 0.61041287 |
122 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.60910227 |
123 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.60760293 |
124 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.60755049 |
125 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.60630273 |
126 | Circadian entrainment_Homo sapiens_hsa04713 | 0.60234770 |
127 | Pathways in cancer_Homo sapiens_hsa05200 | 0.59784596 |
128 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.59128068 |
129 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.58766795 |
130 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58347380 |
131 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.58233652 |
132 | Long-term depression_Homo sapiens_hsa04730 | 0.57755741 |
133 | Ribosome_Homo sapiens_hsa03010 | 0.56543660 |
134 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.56485195 |
135 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.55951205 |
136 | Prion diseases_Homo sapiens_hsa05020 | 0.55171672 |
137 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.54399243 |
138 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.53842571 |
139 | Melanoma_Homo sapiens_hsa05218 | 0.49404993 |