EID1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)5.22663477
2synaptic vesicle maturation (GO:0016188)4.98359628
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.89836571
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.88015423
5locomotory exploration behavior (GO:0035641)4.84095866
6neuron cell-cell adhesion (GO:0007158)4.64078680
7synaptic vesicle exocytosis (GO:0016079)4.59762279
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.54516647
9vocalization behavior (GO:0071625)4.49868427
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.40686859
11dendritic spine morphogenesis (GO:0060997)4.37251475
12neuron recognition (GO:0008038)4.37162254
13protein localization to synapse (GO:0035418)4.30333828
14exploration behavior (GO:0035640)4.28987077
15regulation of synaptic vesicle exocytosis (GO:2000300)4.23953143
16glutamate secretion (GO:0014047)4.18244149
17axonal fasciculation (GO:0007413)4.16820674
18regulation of glutamate receptor signaling pathway (GO:1900449)4.15966604
19dendrite morphogenesis (GO:0048813)3.92826166
20ionotropic glutamate receptor signaling pathway (GO:0035235)3.87303161
21regulation of synapse structural plasticity (GO:0051823)3.81944705
22regulation of long-term neuronal synaptic plasticity (GO:0048169)3.72659765
23regulation of synaptic vesicle transport (GO:1902803)3.64665437
24glutamate receptor signaling pathway (GO:0007215)3.56153480
25positive regulation of mitochondrial fission (GO:0090141)3.52978365
26regulation of neuronal synaptic plasticity (GO:0048168)3.51435094
27synaptic vesicle docking involved in exocytosis (GO:0016081)3.47361803
28neurotransmitter secretion (GO:0007269)3.47286018
29sequestering of actin monomers (GO:0042989)3.45591135
30activation of protein kinase A activity (GO:0034199)3.41089179
31proline transport (GO:0015824)3.40477530
32regulation of dendritic spine morphogenesis (GO:0061001)3.39846245
33negative regulation of synaptic transmission, GABAergic (GO:0032229)3.39236498
34cullin deneddylation (GO:0010388)3.38408677
35postsynaptic membrane organization (GO:0001941)3.36342926
36central nervous system projection neuron axonogenesis (GO:0021952)3.35345271
37negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.34435657
38cell migration in hindbrain (GO:0021535)3.32891006
39regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.27134433
40synaptic transmission, glutamatergic (GO:0035249)3.25616304
41pyrimidine nucleobase catabolic process (GO:0006208)3.21027108
42positive regulation of synapse maturation (GO:0090129)3.19454611
43presynaptic membrane assembly (GO:0097105)3.19430606
44clathrin coat assembly (GO:0048268)3.18964298
45neuronal action potential propagation (GO:0019227)3.18507702
46dendritic spine organization (GO:0097061)3.17465684
47protein deneddylation (GO:0000338)3.16341424
48neuron-neuron synaptic transmission (GO:0007270)3.11310796
49transmission of nerve impulse (GO:0019226)3.10862033
50positive regulation of dendritic spine morphogenesis (GO:0061003)3.08612180
51establishment of mitochondrion localization (GO:0051654)3.07439510
52regulation of excitatory postsynaptic membrane potential (GO:0060079)3.07151457
53negative regulation of microtubule polymerization (GO:0031115)3.06514111
54axon extension (GO:0048675)3.05979465
55protein neddylation (GO:0045116)3.02926396
56organelle transport along microtubule (GO:0072384)3.01032818
57vesicle transport along microtubule (GO:0047496)3.00590011
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.99498007
59regulation of dendritic spine development (GO:0060998)2.99324108
60synapse assembly (GO:0007416)2.97242884
61long-term memory (GO:0007616)2.96904340
62positive regulation of dendritic spine development (GO:0060999)2.95933504
63positive regulation of membrane potential (GO:0045838)2.95217290
64presynaptic membrane organization (GO:0097090)2.94745051
65neurotransmitter-gated ion channel clustering (GO:0072578)2.94256722
66regulation of postsynaptic membrane potential (GO:0060078)2.93787589
67mating behavior (GO:0007617)2.93207505
68gamma-aminobutyric acid signaling pathway (GO:0007214)2.91546889
69innervation (GO:0060384)2.89401970
70synaptic vesicle endocytosis (GO:0048488)2.89191956
71regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.87716718
72synapse organization (GO:0050808)2.87598415
73neuromuscular process controlling balance (GO:0050885)2.85773762
74regulation of vesicle fusion (GO:0031338)2.85022877
75mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.84601675
76regulation of synaptic plasticity (GO:0048167)2.84383445
77cerebellar Purkinje cell layer development (GO:0021680)2.83670678
78G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.82440202
79mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.81941731
80cerebellar granule cell differentiation (GO:0021707)2.79883117
81cellular potassium ion homeostasis (GO:0030007)2.79135017
82intraciliary transport (GO:0042073)2.79056860
83neurotransmitter transport (GO:0006836)2.78673645
84positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.78316858
85regulation of neurotransmitter secretion (GO:0046928)2.78019497
86nucleobase catabolic process (GO:0046113)2.77562407
87positive regulation of synapse assembly (GO:0051965)2.76838895
88auditory behavior (GO:0031223)2.73478169
89membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.72548741
90gamma-aminobutyric acid transport (GO:0015812)2.72261020
91central nervous system neuron axonogenesis (GO:0021955)2.72203983
92positive regulation of synaptic transmission, GABAergic (GO:0032230)2.71825248
93establishment of nucleus localization (GO:0040023)2.71269888
94chaperone-mediated protein transport (GO:0072321)2.70516651
95long-term synaptic potentiation (GO:0060291)2.70235816
96neuron projection extension (GO:1990138)2.69629300
97nonmotile primary cilium assembly (GO:0035058)2.67788918
98DNA double-strand break processing (GO:0000729)2.66682685
99negative regulation of axon extension (GO:0030517)2.66218957
100nerve growth factor signaling pathway (GO:0038180)2.65174668
101cerebral cortex radially oriented cell migration (GO:0021799)2.63790489
102regulation of cAMP-dependent protein kinase activity (GO:2000479)2.63195963
103neuronal ion channel clustering (GO:0045161)2.62480374
104ribonucleoprotein complex disassembly (GO:0032988)2.61413013
105cerebellum development (GO:0021549)2.61303496
106regulation of axon extension (GO:0030516)2.59858423
107behavioral fear response (GO:0001662)2.59322808
108behavioral defense response (GO:0002209)2.59322808
109positive regulation of neurotransmitter secretion (GO:0001956)2.58239677
110dendrite development (GO:0016358)2.57956093
111learning (GO:0007612)2.57869785
112intraspecies interaction between organisms (GO:0051703)2.57420362
113social behavior (GO:0035176)2.57420362
114regulation of development, heterochronic (GO:0040034)2.56940039
115regulation of synaptic transmission, glutamatergic (GO:0051966)2.56896805
116regulation of synapse organization (GO:0050807)2.55992198
117pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.54870456
118negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.50574430
119negative regulation of oligodendrocyte differentiation (GO:0048715)2.48277459
120hippocampus development (GO:0021766)2.46005609
121negative regulation of neurotransmitter transport (GO:0051589)2.43865181
122cholesterol biosynthetic process (GO:0006695)2.43386733
123calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.40148341
124establishment of integrated proviral latency (GO:0075713)2.39364958
125forebrain neuron differentiation (GO:0021879)2.38957500
126positive regulation of amino acid transport (GO:0051957)2.36705828
127pyrimidine nucleotide catabolic process (GO:0006244)2.35327066
128protein localization to cilium (GO:0061512)2.34206036
129organelle disassembly (GO:1903008)2.34122606
130epithelial cell differentiation involved in kidney development (GO:0035850)2.33878891
131DNA damage response, detection of DNA damage (GO:0042769)2.33658852
132response to pheromone (GO:0019236)2.31842724
133regulation of cell communication by electrical coupling (GO:0010649)2.31587871
134ATP synthesis coupled proton transport (GO:0015986)2.31390648
135energy coupled proton transport, down electrochemical gradient (GO:0015985)2.31390648
136mechanosensory behavior (GO:0007638)2.29835696
137L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.26110822
138regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.25125262
139respiratory electron transport chain (GO:0022904)2.23598873
140positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.22942124
141detection of calcium ion (GO:0005513)2.22610915
142branched-chain amino acid catabolic process (GO:0009083)2.21676229
143sterol biosynthetic process (GO:0016126)2.21405059
144DNA integration (GO:0015074)2.20931424
145glial cell proliferation (GO:0014009)2.20895505
146electron transport chain (GO:0022900)2.19691763
147cytoskeleton-dependent intracellular transport (GO:0030705)2.16664262
148regulation of synapse assembly (GO:0051963)2.15370893
149regulation of feeding behavior (GO:0060259)2.14914980
150establishment of viral latency (GO:0019043)2.13725413
151protein-cofactor linkage (GO:0018065)2.13375302
152glycosphingolipid biosynthetic process (GO:0006688)2.13237069
153retinal ganglion cell axon guidance (GO:0031290)2.12156429
154aldehyde catabolic process (GO:0046185)2.11087213
155spinal cord association neuron differentiation (GO:0021527)2.11044221
156negative regulation of heart rate (GO:0010459)2.10633243
157microtubule-based transport (GO:0010970)2.10518871
158cardiac ventricle formation (GO:0003211)2.09782456
159negative regulation of calcium ion transmembrane transport (GO:1903170)2.09447149

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.26432537
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.17344425
3GBX2_23144817_ChIP-Seq_PC3_Human3.16750624
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.04936638
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.02568913
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.81664962
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.81664962
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.74672925
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.66159750
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.64341909
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.61872995
12* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.59574979
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46895293
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.41725743
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.39841857
16RNF2_27304074_Chip-Seq_ESCs_Mouse2.30554577
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.27117134
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.24508861
19REST_21632747_ChIP-Seq_MESCs_Mouse2.24169825
20EWS_26573619_Chip-Seq_HEK293_Human2.22198665
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.15594885
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.15012799
23GABP_17652178_ChIP-ChIP_JURKAT_Human2.14241929
24HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08649574
25KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.08434949
26DROSHA_22980978_ChIP-Seq_HELA_Human2.07668471
27AR_21572438_ChIP-Seq_LNCaP_Human2.07263684
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.06941921
29RARB_27405468_Chip-Seq_BRAIN_Mouse2.05965322
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86165407
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85910538
32ZNF274_21170338_ChIP-Seq_K562_Hela1.81198688
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.81172559
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.77287149
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76012761
36CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.73809907
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.70171975
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.68769702
39RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.68277641
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.67700687
41ELK1_19687146_ChIP-ChIP_HELA_Human1.66598809
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.66012296
43EST1_17652178_ChIP-ChIP_JURKAT_Human1.65236955
44POU5F1_16153702_ChIP-ChIP_HESCs_Human1.62551851
45TAF15_26573619_Chip-Seq_HEK293_Human1.59666642
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.56745179
47WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.56154706
48CREB1_15753290_ChIP-ChIP_HEK293T_Human1.55281532
49TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.54902329
50SMAD4_21799915_ChIP-Seq_A2780_Human1.52513362
51* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51385501
52FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.50353437
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.49723394
54RING1B_27294783_Chip-Seq_ESCs_Mouse1.49651140
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.45594722
56* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44501545
57RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.44263347
58EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44261146
59MYC_18940864_ChIP-ChIP_HL60_Human1.43545852
60SALL1_21062744_ChIP-ChIP_HESCs_Human1.42575256
61NR3C1_23031785_ChIP-Seq_PC12_Mouse1.41454356
62ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40644261
63IGF1R_20145208_ChIP-Seq_DFB_Human1.40631128
64RING1B_27294783_Chip-Seq_NPCs_Mouse1.40079257
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39693554
66P300_19829295_ChIP-Seq_ESCs_Human1.39087327
67* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38318024
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36954208
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.35627458
70ERG_21242973_ChIP-ChIP_JURKAT_Human1.34723716
71FLI1_27457419_Chip-Seq_LIVER_Mouse1.34315817
72CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.33797027
73VDR_22108803_ChIP-Seq_LS180_Human1.33433856
74* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32314966
75SOX2_21211035_ChIP-Seq_LN229_Gbm1.31389703
76BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31155401
77MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30994776
78SOX2_16153702_ChIP-ChIP_HESCs_Human1.30420182
79SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30202549
80* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.29549997
81ZNF217_24962896_ChIP-Seq_MCF-7_Human1.27517523
82WT1_25993318_ChIP-Seq_PODOCYTE_Human1.26167741
83TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25148902
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.24444912
85ETS1_20019798_ChIP-Seq_JURKAT_Human1.24110369
86POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22208829
87FUS_26573619_Chip-Seq_HEK293_Human1.21366554
88AR_25329375_ChIP-Seq_VCAP_Human1.19482098
89PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18394304
90TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18018619
91JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.18005611
92ZFP281_18757296_ChIP-ChIP_E14_Mouse1.16896509
93RNF2_27304074_Chip-Seq_NSC_Mouse1.16711759
94AR_19668381_ChIP-Seq_PC3_Human1.16444017
95IRF1_19129219_ChIP-ChIP_H3396_Human1.15651440
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.15580775
97YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14776885
98SOX9_26525672_Chip-Seq_HEART_Mouse1.14622842
99ARNT_22903824_ChIP-Seq_MCF-7_Human1.14406182
100AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12267586
101TP53_16413492_ChIP-PET_HCT116_Human1.11615245
102WT1_19549856_ChIP-ChIP_CCG9911_Human1.11296369
103YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.11276513
104RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11042518
105TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10611519
106STAT3_23295773_ChIP-Seq_U87_Human1.10565678
107NANOG_18555785_Chip-Seq_ESCs_Mouse1.10396240
108VDR_23849224_ChIP-Seq_CD4+_Human1.10052940
109SMAD_19615063_ChIP-ChIP_OVARY_Human1.09083607
110KDM2B_26808549_Chip-Seq_K562_Human1.08657398
111AHR_22903824_ChIP-Seq_MCF-7_Human1.07697856
112EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.07336130
113EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07292621
114REST_19997604_ChIP-ChIP_NEURONS_Mouse1.06168444
115* TP53_18474530_ChIP-ChIP_U2OS_Human1.05954506
116* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.05900282
117THAP11_20581084_ChIP-Seq_MESCs_Mouse1.04689212
118PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03356979
119KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.01610241
120SMAD3_21741376_ChIP-Seq_ESCs_Human1.01371975
121* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01321695
122P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99621603
123P53_22387025_ChIP-Seq_ESCs_Mouse0.99226804
124POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98667745
125TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98667745
126PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98598245
127ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98559614
128RUNX2_22187159_ChIP-Seq_PCA_Human0.98542433
129HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.98209146
130KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97522473
131GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97309451
132TRIM28_21343339_ChIP-Seq_HEK293_Human0.97194350
133TCF4_23295773_ChIP-Seq_U87_Human0.96719378
134IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96667834
135CBP_20019798_ChIP-Seq_JUKART_Human0.96667834
136STAT6_21828071_ChIP-Seq_BEAS2B_Human0.96441056
137DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94991321
138* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93867844
139HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.93825314
140EP300_21415370_ChIP-Seq_HL-1_Mouse0.93243927
141MYC_18555785_ChIP-Seq_MESCs_Mouse0.92784681
142TP53_20018659_ChIP-ChIP_R1E_Mouse0.92470787
143TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92443780
144NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.91909187
145NRF2_20460467_ChIP-Seq_MEFs_Mouse0.91909187
146JUN_21703547_ChIP-Seq_K562_Human0.91716245
147RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.91402290
148PRDM14_20953172_ChIP-Seq_ESCs_Human0.90624740
149OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.90623967
150* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90002508
151UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.89215343

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.56402015
2MP0003880_abnormal_central_pattern4.39267680
3MP0003635_abnormal_synaptic_transmissio3.70084231
4MP0004270_analgesia3.63248695
5MP0002063_abnormal_learning/memory/cond2.99866301
6MP0009745_abnormal_behavioral_response2.74042065
7MP0000778_abnormal_nervous_system2.54911635
8MP0002064_seizures2.51160563
9MP0005423_abnormal_somatic_nervous2.47887060
10MP0009780_abnormal_chondrocyte_physiolo2.46437374
11MP0002734_abnormal_mechanical_nocicepti2.40277352
12MP0002572_abnormal_emotion/affect_behav2.36978928
13MP0001968_abnormal_touch/_nociception2.28336509
14MP0001486_abnormal_startle_reflex2.18490856
15MP0003122_maternal_imprinting2.15984061
16MP0009046_muscle_twitch2.10354942
17MP0002272_abnormal_nervous_system2.03701861
18MP0008789_abnormal_olfactory_epithelium2.02555424
19MP0002184_abnormal_innervation2.01645601
20MP0002733_abnormal_thermal_nociception1.91423399
21MP0001440_abnormal_grooming_behavior1.90324907
22MP0002909_abnormal_adrenal_gland1.83093700
23MP0003329_amyloid_beta_deposits1.81287725
24MP0006276_abnormal_autonomic_nervous1.81224801
25MP0004811_abnormal_neuron_physiology1.74045759
26MP0002638_abnormal_pupillary_reflex1.73951585
27MP0005171_absent_coat_pigmentation1.73774331
28MP0002557_abnormal_social/conspecific_i1.71803547
29MP0001970_abnormal_pain_threshold1.68741838
30MP0000569_abnormal_digit_pigmentation1.68676359
31MP0004858_abnormal_nervous_system1.68351876
32MP0000955_abnormal_spinal_cord1.67751103
33MP0002067_abnormal_sensory_capabilities1.65292800
34MP0002735_abnormal_chemical_nociception1.63615016
35MP0004885_abnormal_endolymph1.61763582
36MP0005253_abnormal_eye_physiology1.59449369
37MP0001501_abnormal_sleep_pattern1.57885273
38MP0002736_abnormal_nociception_after1.55349323
39MP0000049_abnormal_middle_ear1.54556299
40MP0005386_behavior/neurological_phenoty1.54507550
41MP0004924_abnormal_behavior1.54507550
42MP0002882_abnormal_neuron_morphology1.48918817
43MP0002653_abnormal_ependyma_morphology1.48734600
44MP0003787_abnormal_imprinting1.46210740
45MP0010234_abnormal_vibrissa_follicle1.46091961
46MP0008569_lethality_at_weaning1.44559861
47MP0001984_abnormal_olfaction1.42234351
48MP0002751_abnormal_autonomic_nervous1.37980303
49MP0004215_abnormal_myocardial_fiber1.36913091
50MP0003136_yellow_coat_color1.34615268
51MP0002066_abnormal_motor_capabilities/c1.29201444
52MP0002152_abnormal_brain_morphology1.24447833
53MP0008877_abnormal_DNA_methylation1.23369566
54MP0000372_irregular_coat_pigmentation1.22681379
55MP0000013_abnormal_adipose_tissue1.21554233
56MP0005187_abnormal_penis_morphology1.21506770
57MP0005623_abnormal_meninges_morphology1.20269610
58MP0004133_heterotaxia1.19975498
59MP0005645_abnormal_hypothalamus_physiol1.18280461
60MP0006292_abnormal_olfactory_placode1.16886122
61MP0001299_abnormal_eye_distance/1.14732333
62MP0000631_abnormal_neuroendocrine_gland1.12468779
63MP0000537_abnormal_urethra_morphology1.11245778
64MP0004742_abnormal_vestibular_system1.09941778
65MP0004145_abnormal_muscle_electrophysio1.08929792
66MP0003879_abnormal_hair_cell1.08874792
67MP0003634_abnormal_glial_cell1.06548145
68MP0000751_myopathy1.05925240
69MP0003633_abnormal_nervous_system1.04581093
70MP0001905_abnormal_dopamine_level1.02947089
71MP0009697_abnormal_copulation1.02016655
72MP0002234_abnormal_pharynx_morphology1.01029846
73MP0003283_abnormal_digestive_organ1.00904607
74MP0003121_genomic_imprinting1.00630591
75MP0001502_abnormal_circadian_rhythm1.00425466
76MP0002233_abnormal_nose_morphology0.99751842
77MP0003011_delayed_dark_adaptation0.96904934
78MP0003567_abnormal_fetal_cardiomyocyte0.96848569
79MP0005503_abnormal_tendon_morphology0.95593782
80MP0004084_abnormal_cardiac_muscle0.94195990
81MP0008058_abnormal_DNA_repair0.93124524
82MP0000920_abnormal_myelination0.92171955
83MP0005248_abnormal_Harderian_gland0.91930820
84MP0005646_abnormal_pituitary_gland0.91504833
85MP0001188_hyperpigmentation0.91470713
86MP0003861_abnormal_nervous_system0.91205244
87MP0002837_dystrophic_cardiac_calcinosis0.90352548
88MP0001293_anophthalmia0.89863535
89MP0003631_nervous_system_phenotype0.89335969
90MP0001348_abnormal_lacrimal_gland0.89092859
91MP0008995_early_reproductive_senescence0.88472411
92MP0000026_abnormal_inner_ear0.88256662
93MP0004085_abnormal_heartbeat0.86871160
94MP0002938_white_spotting0.86021772
95MP0001529_abnormal_vocalization0.84980240
96MP0002752_abnormal_somatic_nervous0.84937420
97MP0003123_paternal_imprinting0.83919715
98MP0003385_abnormal_body_wall0.83508993
99MP0005391_vision/eye_phenotype0.83498957
100MP0006072_abnormal_retinal_apoptosis0.83455198
101MP0001177_atelectasis0.83228326
102MP0008932_abnormal_embryonic_tissue0.81897621
103MP0004147_increased_porphyrin_level0.81621786
104MP0001963_abnormal_hearing_physiology0.81224134
105MP0003937_abnormal_limbs/digits/tail_de0.80647586
106MP0000534_abnormal_ureter_morphology0.80128615
107MP0002069_abnormal_eating/drinking_beha0.78836855
108MP0000604_amyloidosis0.77958189
109MP0005394_taste/olfaction_phenotype0.75382689
110MP0005499_abnormal_olfactory_system0.75382689
111MP0002822_catalepsy0.75105134
112MP0002229_neurodegeneration0.74039787
113MP0001485_abnormal_pinna_reflex0.72786845
114MP0001943_abnormal_respiration0.71032210
115MP0003632_abnormal_nervous_system0.70565103
116MP0002896_abnormal_bone_mineralization0.70174498
117MP0003938_abnormal_ear_development0.69988239
118MP0004142_abnormal_muscle_tone0.69787634
119MP0010386_abnormal_urinary_bladder0.69301657
120MP0004484_altered_response_of0.67714854
121MP0004233_abnormal_muscle_weight0.66702930
122MP0005551_abnormal_eye_electrophysiolog0.66664724
123MP0003119_abnormal_digestive_system0.66651148
124MP0002090_abnormal_vision0.66398608
125MP0002081_perinatal_lethality0.65529602
126MP0003137_abnormal_impulse_conducting0.65520771
127MP0003942_abnormal_urinary_system0.65509029
128MP0009250_abnormal_appendicular_skeleto0.62883955
129MP0002102_abnormal_ear_morphology0.61542724

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.69944911
2Visual hallucinations (HP:0002367)4.69336427
3Myokymia (HP:0002411)4.49056566
4Focal seizures (HP:0007359)4.13195426
5Papilledema (HP:0001085)3.78401883
6Supranuclear gaze palsy (HP:0000605)3.62425422
7Mutism (HP:0002300)3.54813947
8Cerebral inclusion bodies (HP:0100314)3.45122285
9Atonic seizures (HP:0010819)3.41885740
10Epileptic encephalopathy (HP:0200134)3.39456124
11Gait imbalance (HP:0002141)3.39054392
12Neurofibrillary tangles (HP:0002185)3.32218518
13Termporal pattern (HP:0011008)3.25112500
14Insidious onset (HP:0003587)3.25112500
15Medial flaring of the eyebrow (HP:0010747)3.16919077
16Congenital primary aphakia (HP:0007707)3.16041745
17Action tremor (HP:0002345)3.10920821
18Absence seizures (HP:0002121)3.08072338
19Ankle clonus (HP:0011448)3.04035639
20Broad-based gait (HP:0002136)3.01393037
21Drooling (HP:0002307)2.98093249
22Excessive salivation (HP:0003781)2.98093249
23Limb dystonia (HP:0002451)2.96902940
24Amyotrophic lateral sclerosis (HP:0007354)2.94860907
25Nephrogenic diabetes insipidus (HP:0009806)2.90261847
26Progressive cerebellar ataxia (HP:0002073)2.89988573
27Acute necrotizing encephalopathy (HP:0006965)2.88675027
28Exercise-induced muscle cramps (HP:0003710)2.82763138
29Cortical dysplasia (HP:0002539)2.79781305
30Agitation (HP:0000713)2.79433740
31Abnormality of the corticospinal tract (HP:0002492)2.78664716
32Inappropriate behavior (HP:0000719)2.75797855
33Megalencephaly (HP:0001355)2.72972218
34Generalized tonic-clonic seizures (HP:0002069)2.72646731
35Amblyopia (HP:0000646)2.72064649
36Dialeptic seizures (HP:0011146)2.70965468
37Abnormal mitochondria in muscle tissue (HP:0008316)2.68338345
38Depression (HP:0000716)2.63943157
39Apathy (HP:0000741)2.53475140
40Progressive macrocephaly (HP:0004481)2.51142151
41Febrile seizures (HP:0002373)2.48998808
42Acute encephalopathy (HP:0006846)2.45587518
43Mitochondrial inheritance (HP:0001427)2.45568097
44Failure to thrive in infancy (HP:0001531)2.44473677
45Genital tract atresia (HP:0001827)2.44124833
46Poor eye contact (HP:0000817)2.43302312
47Vaginal atresia (HP:0000148)2.43262277
48Buphthalmos (HP:0000557)2.42863912
49Truncal ataxia (HP:0002078)2.42449837
50Anxiety (HP:0000739)2.40693064
51Abnormality of the musculature of the pelvis (HP:0001469)2.40251179
52Abnormality of the hip-girdle musculature (HP:0001445)2.40251179
53Progressive inability to walk (HP:0002505)2.39785772
54Pancreatic fibrosis (HP:0100732)2.39178865
55Increased hepatocellular lipid droplets (HP:0006565)2.37184314
56Urinary urgency (HP:0000012)2.37153333
57True hermaphroditism (HP:0010459)2.36718996
58Genetic anticipation (HP:0003743)2.32714093
59Abnormality of the labia minora (HP:0012880)2.32377920
60Specific learning disability (HP:0001328)2.30185266
61Diminished motivation (HP:0000745)2.29278420
62Atrophy/Degeneration involving motor neurons (HP:0007373)2.27556529
63Akinesia (HP:0002304)2.26935593
64Myotonia (HP:0002486)2.24460469
65Insomnia (HP:0100785)2.23428210
66Hyperventilation (HP:0002883)2.22824889
67Impaired vibration sensation in the lower limbs (HP:0002166)2.21575877
68Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.21221645
69Cerebral edema (HP:0002181)2.20929047
70Abnormality of midbrain morphology (HP:0002418)2.20485419
71Molar tooth sign on MRI (HP:0002419)2.20485419
72Urinary bladder sphincter dysfunction (HP:0002839)2.19712617
73Increased intramyocellular lipid droplets (HP:0012240)2.19642344
74Lipid accumulation in hepatocytes (HP:0006561)2.19053726
75Hepatoblastoma (HP:0002884)2.17298088
76Broad foot (HP:0001769)2.16628332
77Abnormal eating behavior (HP:0100738)2.16493018
78Nephronophthisis (HP:0000090)2.16293307
79Torticollis (HP:0000473)2.15175888
80Pheochromocytoma (HP:0002666)2.15027844
81Spastic gait (HP:0002064)2.14307762
82Stereotypic behavior (HP:0000733)2.13313076
83Dysmetria (HP:0001310)2.13154437
84Abnormal social behavior (HP:0012433)2.11676731
85Impaired social interactions (HP:0000735)2.11676731
86Hemiparesis (HP:0001269)2.10773593
87Hypoventilation (HP:0002791)2.10773394
88EEG with generalized epileptiform discharges (HP:0011198)2.09758161
89Epileptiform EEG discharges (HP:0011182)2.09749608
90Diplopia (HP:0000651)2.09586951
91Abnormality of binocular vision (HP:0011514)2.09586951
92Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.09232791
93Degeneration of the lateral corticospinal tracts (HP:0002314)2.09232791
94Rimmed vacuoles (HP:0003805)2.08953298
95Obstructive sleep apnea (HP:0002870)2.08216877
96Ankyloglossia (HP:0010296)2.06710416
97Disinhibition (HP:0000734)2.05991743
98Increased CSF lactate (HP:0002490)2.05019462
99Split foot (HP:0001839)2.04652256
100Postaxial hand polydactyly (HP:0001162)2.04576803
101Hypsarrhythmia (HP:0002521)2.02071735
102Dysdiadochokinesis (HP:0002075)2.01683234
103Macroorchidism (HP:0000053)1.99671483
104Hepatic necrosis (HP:0002605)1.99519481
105Hepatocellular necrosis (HP:0001404)1.99009126
106Sporadic (HP:0003745)1.98538192
107Absent speech (HP:0001344)1.98495452
108Polyphagia (HP:0002591)1.98148056
109Poor suck (HP:0002033)1.98138373
110Renal Fanconi syndrome (HP:0001994)1.96805919
111Intention tremor (HP:0002080)1.96697013
112Aplasia/Hypoplasia of the brainstem (HP:0007362)1.95231520
113Hypoplasia of the brainstem (HP:0002365)1.95231520
114Abnormality of salivation (HP:0100755)1.94897173
115Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94175372
116Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94175372
117Overgrowth (HP:0001548)1.92778131
118Limb-girdle muscle atrophy (HP:0003797)1.91632692
1193-Methylglutaconic aciduria (HP:0003535)1.91036515
120Lower limb muscle weakness (HP:0007340)1.89857618
121Decreased testicular size (HP:0008734)1.89680471
122Focal dystonia (HP:0004373)1.87770245
123Heterochromia iridis (HP:0001100)1.87728156
124Pancreatic cysts (HP:0001737)1.86627567
125Methylmalonic acidemia (HP:0002912)1.85359359
126Lower limb asymmetry (HP:0100559)1.85328432
127Increased serum pyruvate (HP:0003542)1.85085280
128Bronchomalacia (HP:0002780)1.82666261
129Pointed chin (HP:0000307)1.82599908
130Degeneration of anterior horn cells (HP:0002398)1.81494259
131Abnormality of the anterior horn cell (HP:0006802)1.81494259
132Poor coordination (HP:0002370)1.80934769
133Cerebral hypomyelination (HP:0006808)1.80858970
134Renal cortical cysts (HP:0000803)1.80356326
135Gaze-evoked nystagmus (HP:0000640)1.78361106
136Rapidly progressive (HP:0003678)1.78295228
137Optic nerve hypoplasia (HP:0000609)1.77561655
138Abnormality of the lower motor neuron (HP:0002366)1.77439052
139Retinal dysplasia (HP:0007973)1.76207177
140Abnormality of glycolysis (HP:0004366)1.76008679
141Pelvic girdle muscle weakness (HP:0003749)1.75656355
142Aqueductal stenosis (HP:0002410)1.74513703
143Shoulder girdle muscle weakness (HP:0003547)1.74395751
144Hyperthyroidism (HP:0000836)1.73937880
145Exotropia (HP:0000577)1.73518318
146Postural instability (HP:0002172)1.72960734
147Lactic acidosis (HP:0003128)1.72791119
148Lissencephaly (HP:0001339)1.72705908
149Increased muscle lipid content (HP:0009058)1.72642172
150Neuronal loss in central nervous system (HP:0002529)1.72042864
151Neuroendocrine neoplasm (HP:0100634)1.71651590
152Craniofacial dystonia (HP:0012179)1.71309513
153Neoplasm of the peripheral nervous system (HP:0100007)1.70214486
154Aplasia/Hypoplasia of the lens (HP:0008063)1.69751451
155Postaxial foot polydactyly (HP:0001830)1.68831488
156Fetal akinesia sequence (HP:0001989)1.68728254
157Congenital glaucoma (HP:0001087)1.67628586
158Pachygyria (HP:0001302)1.67598356
159Impaired smooth pursuit (HP:0007772)1.66379774
160Sacral dimple (HP:0000960)1.66333513
161Delayed gross motor development (HP:0002194)1.64395874
162Thyroid-stimulating hormone excess (HP:0002925)1.64143529
163Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.63932805
164Limb-girdle muscle weakness (HP:0003325)1.63642164
165Left ventricular hypertrophy (HP:0001712)1.63040646
166Intestinal atresia (HP:0011100)1.62796677
167Morphological abnormality of the pyramidal tract (HP:0002062)1.62459190
168Exercise intolerance (HP:0003546)1.62432014
169Hyperglycinemia (HP:0002154)1.61488426
170Postnatal microcephaly (HP:0005484)1.61429218

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.42716400
2NTRK33.43916654
3MAP3K93.39933764
4BCKDK3.11931147
5EPHA42.95021337
6MAP3K42.66086444
7MINK12.65279258
8MAP4K22.27941893
9PAK62.04111366
10NTRK22.04049913
11TRIM282.02578984
12MAP2K71.95368158
13NTRK11.92812166
14DAPK21.86844072
15KSR21.85487116
16KSR11.83632958
17MAPK131.78980118
18SRPK11.77925631
19PLK21.75441042
20PINK11.73603827
21TESK11.70197011
22PNCK1.66543811
23PHKG11.64831804
24PHKG21.64831804
25CAMKK11.59320673
26SIK21.58951676
27CASK1.57079835
28UHMK11.53782595
29CDK51.52188731
30MAP2K41.50408315
31MAP3K121.50061589
32LATS21.47988836
33MKNK11.45120327
34PRKD31.42834154
35CSNK1G21.42143588
36MAP3K21.36748422
37ERBB31.35266222
38NEK11.31595073
39TYRO31.28749243
40RPS6KA41.24570785
41TNIK1.23106908
42RIPK41.21056087
43DYRK21.16389230
44EIF2AK31.13211107
45RET1.12622389
46PAK31.12493305
47GRK51.11970741
48SCYL21.09225775
49CAMKK21.04967447
50CDK141.04543554
51DYRK31.02373471
52CDK191.00260888
53PRKCG0.98241075
54DDR20.97203981
55CSNK1G30.96778388
56DYRK1A0.95584434
57CAMK2A0.92670060
58CCNB10.91928751
59GRK10.91579003
60DAPK10.91249688
61VRK10.90877923
62CDK150.90793626
63FES0.90736430
64TIE10.90725097
65CDK180.90070136
66VRK20.89101738
67LIMK10.88714040
68CSNK1A1L0.88577739
69RIPK10.87025528
70TESK20.86641178
71FGFR20.85470702
72CDC70.85171382
73CAMK1G0.83736470
74PLK30.82733354
75STK110.81853890
76CAMK2B0.80947789
77CDK11A0.78460204
78MYLK0.78405512
79PRPF4B0.78200484
80ARAF0.76941290
81DYRK1B0.76836648
82PDGFRA0.76745410
83MARK20.76728185
84FGR0.75736861
85OBSCN0.74888543
86PKN10.73567314
87EPHA30.71815403
88BMPR1B0.68934914
89STK390.66609760
90MKNK20.65997034
91ADRBK20.65969865
92PTK2B0.65110854
93PRKCH0.64736336
94OXSR10.64592612
95FER0.62863036
96PRKCZ0.62577541
97BCR0.62251934
98TSSK60.61612530
99CSNK1G10.59972537
100RAF10.59770151
101CAMK2G0.59000491
102ALK0.58527290
103PRKCE0.58387718
104ROCK20.58372037
105FYN0.58027725
106WEE10.57942953
107DMPK0.57206493
108PBK0.56866218
109EPHB20.55193900
110RPS6KA20.54292231
111MAP3K60.54240129
112FLT30.54105797
113SGK10.52475032
114KDR0.52182830
115HIPK20.51088728
116EIF2AK10.50963257
117CAMK2D0.50617026
118NUAK10.50268823
119PKN20.48488563
120WNK30.48416939
121TRIB30.47446221
122ILK0.47107932
123SGK2230.46968567
124SGK4940.46968567
125PLK40.45709367
126MAPKAPK50.44649395
127ERBB40.44230048
128INSRR0.43793889
129CDK30.43770307
130CAMK10.42887717
131CSNK1A10.42398549
132EIF2AK20.42297493
133WNK10.41837171
134PLK10.41642464
135CSNK1D0.40642280
136PRKACB0.39917272
137MAPK100.39872048
138BMPR20.39690531
139PRKACA0.38994072
140STK380.38682700
141ROCK10.38279745
142CSNK1E0.38085041
143ADRBK10.37957253
144WNK40.37838406
145RPS6KA50.37319267
146RPS6KA30.37088303
147AKT20.37049750
148TAOK10.36242981
149PRKG10.33947174

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.16073490
2Nicotine addiction_Homo sapiens_hsa050332.74451838
3Oxidative phosphorylation_Homo sapiens_hsa001902.71520832
4Parkinsons disease_Homo sapiens_hsa050122.65924151
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.54517654
6Long-term potentiation_Homo sapiens_hsa047202.41907305
7Synaptic vesicle cycle_Homo sapiens_hsa047212.41651282
8Circadian entrainment_Homo sapiens_hsa047132.36336238
9Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.35972525
10Olfactory transduction_Homo sapiens_hsa047402.30261472
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.26669262
12GABAergic synapse_Homo sapiens_hsa047272.24717965
13Glutamatergic synapse_Homo sapiens_hsa047242.22848514
14Dopaminergic synapse_Homo sapiens_hsa047282.12873685
15Amphetamine addiction_Homo sapiens_hsa050312.12372511
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.09309650
17Propanoate metabolism_Homo sapiens_hsa006402.07657492
18Morphine addiction_Homo sapiens_hsa050322.06294203
19Cholinergic synapse_Homo sapiens_hsa047251.84648176
20Renin secretion_Homo sapiens_hsa049241.80769555
21Salivary secretion_Homo sapiens_hsa049701.76978547
22Insulin secretion_Homo sapiens_hsa049111.75464922
23Axon guidance_Homo sapiens_hsa043601.74420919
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.74233364
25Long-term depression_Homo sapiens_hsa047301.73815907
26Gastric acid secretion_Homo sapiens_hsa049711.68859799
27Huntingtons disease_Homo sapiens_hsa050161.67225744
28Serotonergic synapse_Homo sapiens_hsa047261.63573941
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.63459407
30Cocaine addiction_Homo sapiens_hsa050301.62286073
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60071954
32Steroid biosynthesis_Homo sapiens_hsa001001.57352343
33Proteasome_Homo sapiens_hsa030501.57304868
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57218966
35Gap junction_Homo sapiens_hsa045401.55631329
36Fatty acid elongation_Homo sapiens_hsa000621.54792759
37Oxytocin signaling pathway_Homo sapiens_hsa049211.54259399
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.54141380
39Butanoate metabolism_Homo sapiens_hsa006501.49259255
40Taste transduction_Homo sapiens_hsa047421.48082903
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.42452953
42GnRH signaling pathway_Homo sapiens_hsa049121.41013683
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.40236764
44Estrogen signaling pathway_Homo sapiens_hsa049151.38639049
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.36098168
46Glioma_Homo sapiens_hsa052141.33620033
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.31387475
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29991085
49Spliceosome_Homo sapiens_hsa030401.27995287
50Melanogenesis_Homo sapiens_hsa049161.27502905
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26554941
52Pyruvate metabolism_Homo sapiens_hsa006201.22107821
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.21172189
54Calcium signaling pathway_Homo sapiens_hsa040201.20496256
55cAMP signaling pathway_Homo sapiens_hsa040241.16452813
56Type II diabetes mellitus_Homo sapiens_hsa049301.15732601
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.14361815
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13610231
59Base excision repair_Homo sapiens_hsa034101.12586019
60ErbB signaling pathway_Homo sapiens_hsa040121.11185945
61Non-homologous end-joining_Homo sapiens_hsa034501.09422578
62cGMP-PKG signaling pathway_Homo sapiens_hsa040221.08283898
63Mismatch repair_Homo sapiens_hsa034301.04288908
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.03575689
65Carbon metabolism_Homo sapiens_hsa012001.01057118
66Collecting duct acid secretion_Homo sapiens_hsa049660.98880509
67RNA polymerase_Homo sapiens_hsa030200.97812874
68Vibrio cholerae infection_Homo sapiens_hsa051100.96328613
69Renal cell carcinoma_Homo sapiens_hsa052110.95113581
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95091052
71Cysteine and methionine metabolism_Homo sapiens_hsa002700.93672447
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93300884
73Dorso-ventral axis formation_Homo sapiens_hsa043200.91445884
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.91408991
75Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.90893755
76Oocyte meiosis_Homo sapiens_hsa041140.90015127
77RNA degradation_Homo sapiens_hsa030180.89716009
78beta-Alanine metabolism_Homo sapiens_hsa004100.89466294
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88926968
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.88468577
81Peroxisome_Homo sapiens_hsa041460.88396214
82Biosynthesis of amino acids_Homo sapiens_hsa012300.88305912
83Cardiac muscle contraction_Homo sapiens_hsa042600.88081090
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.87483387
85Endometrial cancer_Homo sapiens_hsa052130.87266472
86VEGF signaling pathway_Homo sapiens_hsa043700.86711947
87Phototransduction_Homo sapiens_hsa047440.86469350
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85544499
89Alcoholism_Homo sapiens_hsa050340.84612635
90Circadian rhythm_Homo sapiens_hsa047100.83574378
91Nucleotide excision repair_Homo sapiens_hsa034200.82787743
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.82599205
93Dilated cardiomyopathy_Homo sapiens_hsa054140.82229091
94Basal transcription factors_Homo sapiens_hsa030220.81660750
95Wnt signaling pathway_Homo sapiens_hsa043100.81488439
96Thyroid hormone synthesis_Homo sapiens_hsa049180.81089340
97Pancreatic secretion_Homo sapiens_hsa049720.81023777
98RNA transport_Homo sapiens_hsa030130.78893750
99Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78785051
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77961935
101Colorectal cancer_Homo sapiens_hsa052100.77350469
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76786636
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.76141920
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75062788
105Ras signaling pathway_Homo sapiens_hsa040140.74613094
106MAPK signaling pathway_Homo sapiens_hsa040100.74562708
107Choline metabolism in cancer_Homo sapiens_hsa052310.74176251
108Regulation of autophagy_Homo sapiens_hsa041400.74155315
109Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73168875
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.72478037
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.72088152
112Fatty acid metabolism_Homo sapiens_hsa012120.71661521
113Fanconi anemia pathway_Homo sapiens_hsa034600.68598985
114Rap1 signaling pathway_Homo sapiens_hsa040150.68452136
115mTOR signaling pathway_Homo sapiens_hsa041500.67758533
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66114878
117Folate biosynthesis_Homo sapiens_hsa007900.65856696
118mRNA surveillance pathway_Homo sapiens_hsa030150.65416450
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64962601
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64380240
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64160288
122Endocytosis_Homo sapiens_hsa041440.63593744
123Hedgehog signaling pathway_Homo sapiens_hsa043400.63322914
124Non-small cell lung cancer_Homo sapiens_hsa052230.63054494
125Arginine and proline metabolism_Homo sapiens_hsa003300.61018581
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60384462
127Purine metabolism_Homo sapiens_hsa002300.60205534
128Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58603926
129Alzheimers disease_Homo sapiens_hsa050100.57261842
130Glucagon signaling pathway_Homo sapiens_hsa049220.55571808
131Metabolic pathways_Homo sapiens_hsa011000.53260114
132Hippo signaling pathway_Homo sapiens_hsa043900.52418939
133Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.51181331
134Insulin signaling pathway_Homo sapiens_hsa049100.50517196
135Focal adhesion_Homo sapiens_hsa045100.50361739
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50019982
137Platelet activation_Homo sapiens_hsa046110.49887236
138DNA replication_Homo sapiens_hsa030300.49615567
139Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49502233
140Prion diseases_Homo sapiens_hsa050200.49359029
141Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48069159
142Tight junction_Homo sapiens_hsa045300.47516270
143Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47492398
144Pyrimidine metabolism_Homo sapiens_hsa002400.46637309
145Sulfur relay system_Homo sapiens_hsa041220.46243684
146Chemokine signaling pathway_Homo sapiens_hsa040620.44510904
147Vitamin B6 metabolism_Homo sapiens_hsa007500.44178000
148Proteoglycans in cancer_Homo sapiens_hsa052050.44176255
149Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44004053
150Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43846531
151Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43358036
152Melanoma_Homo sapiens_hsa052180.42899348
153Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42292360
154Ovarian steroidogenesis_Homo sapiens_hsa049130.41617558
155Pancreatic cancer_Homo sapiens_hsa052120.41279235

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