EID2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)6.18237068
2axon ensheathment in central nervous system (GO:0032291)5.69429674
3central nervous system myelination (GO:0022010)5.69429674
4histone H2B ubiquitination (GO:0033523)5.44232188
5neuron cell-cell adhesion (GO:0007158)5.03890307
6regulation of short-term neuronal synaptic plasticity (GO:0048172)5.01321208
7viral transcription (GO:0019083)4.95719542
8vocalization behavior (GO:0071625)4.95389245
9protein localization to synapse (GO:0035418)4.88923529
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.87785805
11synaptic vesicle exocytosis (GO:0016079)4.84451741
12translational termination (GO:0006415)4.76127088
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.70481648
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.40996805
15synaptic vesicle maturation (GO:0016188)4.38078051
16layer formation in cerebral cortex (GO:0021819)4.37587357
17neuron recognition (GO:0008038)4.32995170
18negative regulation of oligodendrocyte differentiation (GO:0048715)4.31174821
19maturation of SSU-rRNA (GO:0030490)4.28988225
20locomotory exploration behavior (GO:0035641)4.26768299
21regulation of glutamate receptor signaling pathway (GO:1900449)4.20486763
22dendritic spine morphogenesis (GO:0060997)4.15227408
23glutamate secretion (GO:0014047)4.08861042
24neuronal action potential propagation (GO:0019227)4.05341482
25regulation of synaptic vesicle exocytosis (GO:2000300)4.02568639
26axonal fasciculation (GO:0007413)4.00817838
27ionotropic glutamate receptor signaling pathway (GO:0035235)3.98625717
28translational elongation (GO:0006414)3.98526663
29exploration behavior (GO:0035640)3.89235349
30substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.87541862
31substrate-independent telencephalic tangential migration (GO:0021826)3.87541862
32SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.83974048
33cotranslational protein targeting to membrane (GO:0006613)3.82533865
34protein targeting to ER (GO:0045047)3.81786395
35viral life cycle (GO:0019058)3.80739883
36cellular protein complex disassembly (GO:0043624)3.74190225
37establishment of protein localization to endoplasmic reticulum (GO:0072599)3.73924967
38regulation of long-term neuronal synaptic plasticity (GO:0048169)3.72040147
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.71667792
40neurotransmitter secretion (GO:0007269)3.71181560
41nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65013118
42glutamate receptor signaling pathway (GO:0007215)3.64656089
43negative regulation of astrocyte differentiation (GO:0048712)3.63450776
44cell migration in hindbrain (GO:0021535)3.60696624
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.56503956
46protein localization to endoplasmic reticulum (GO:0070972)3.54646077
47regulation of neuronal synaptic plasticity (GO:0048168)3.49725792
48synaptic transmission, glutamatergic (GO:0035249)3.43726157
49heterochromatin organization (GO:0070828)3.42766879
50neuron-neuron synaptic transmission (GO:0007270)3.42718835
51transmission of nerve impulse (GO:0019226)3.41896287
52cerebral cortex neuron differentiation (GO:0021895)3.41714599
53regulation of synaptic vesicle transport (GO:1902803)3.39849731
54positive regulation of synapse maturation (GO:0090129)3.37215331
55energy coupled proton transport, down electrochemical gradient (GO:0015985)3.37198581
56ATP synthesis coupled proton transport (GO:0015986)3.37198581
57proline transport (GO:0015824)3.37013534
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.34868282
59negative regulation of microtubule polymerization (GO:0031115)3.34717219
60protein complex disassembly (GO:0043241)3.31945555
61regulation of synapse structural plasticity (GO:0051823)3.27552592
62postsynaptic membrane organization (GO:0001941)3.26443343
63chaperone-mediated protein complex assembly (GO:0051131)3.23340370
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.22561082
65mating behavior (GO:0007617)3.21775440
66regulation of dendritic spine morphogenesis (GO:0061001)3.21775430
67mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.19712780
68innervation (GO:0060384)3.18612616
69positive regulation of synapse assembly (GO:0051965)3.18497535
70positive regulation of dendritic spine morphogenesis (GO:0061003)3.18373222
71long-term memory (GO:0007616)3.18238034
72neuroblast proliferation (GO:0007405)3.17769234
73macromolecular complex disassembly (GO:0032984)3.16948361
74cellular potassium ion homeostasis (GO:0030007)3.15534418
75synaptic vesicle docking involved in exocytosis (GO:0016081)3.15485149
76regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.14805348
77gamma-aminobutyric acid transport (GO:0015812)3.14229423
78regulation of excitatory postsynaptic membrane potential (GO:0060079)3.12321515
79translational initiation (GO:0006413)3.11305732
80response to histamine (GO:0034776)3.10891744
81behavioral response to nicotine (GO:0035095)3.09959534
82chaperone-mediated protein transport (GO:0072321)3.09631911
83ribosomal large subunit biogenesis (GO:0042273)3.09047284
84neurotransmitter transport (GO:0006836)3.07665993
85regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.07621129
86synaptic vesicle endocytosis (GO:0048488)3.07596819
87presynaptic membrane assembly (GO:0097105)3.03347314
88regulation of postsynaptic membrane potential (GO:0060078)3.02760033
89ribosomal small subunit assembly (GO:0000028)3.01811224
90neuromuscular process controlling posture (GO:0050884)3.01592789
91negative regulation of glial cell differentiation (GO:0045686)2.99407919
92membrane repolarization (GO:0086009)2.97959833
93positive regulation of membrane potential (GO:0045838)2.97838726
94pyrimidine nucleobase catabolic process (GO:0006208)2.94490951
95dendrite morphogenesis (GO:0048813)2.94188790
96synapse assembly (GO:0007416)2.94127444
97regulation of glycogen (starch) synthase activity (GO:2000465)2.93898819
98positive regulation of dendritic spine development (GO:0060999)2.91832584
99regulation of vesicle fusion (GO:0031338)2.90144365
100central nervous system projection neuron axonogenesis (GO:0021952)2.88886078
101neuromuscular process controlling balance (GO:0050885)2.88090466
102positive regulation of synaptic transmission, GABAergic (GO:0032230)2.88070448
103activation of protein kinase A activity (GO:0034199)2.87616394
104auditory behavior (GO:0031223)2.86587145
105behavioral response to cocaine (GO:0048148)2.86457488
106behavioral fear response (GO:0001662)2.84941973
107behavioral defense response (GO:0002209)2.84941973
108prepulse inhibition (GO:0060134)2.83704824
109regulation of synaptic plasticity (GO:0048167)2.83337613
110presynaptic membrane organization (GO:0097090)2.82959480
111synapse organization (GO:0050808)2.81664796
112regulation of protein kinase A signaling (GO:0010738)2.81258099
113regulation of neurotransmitter levels (GO:0001505)2.80239404
114cerebellar Purkinje cell differentiation (GO:0021702)2.79244567
115neurotransmitter-gated ion channel clustering (GO:0072578)2.78394045
116regulation of autophagic vacuole assembly (GO:2000785)2.78192752
117protein targeting to membrane (GO:0006612)2.77560922
118regulation of respiratory system process (GO:0044065)2.77319991
119intraspecies interaction between organisms (GO:0051703)2.76783013
120social behavior (GO:0035176)2.76783013
121left/right pattern formation (GO:0060972)2.75511516
122cerebellum development (GO:0021549)2.75174285
123dendrite development (GO:0016358)2.75014815
124regulation of synaptic transmission, GABAergic (GO:0032228)2.74935076
125positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74764572
126fear response (GO:0042596)2.74613930
127regulation of dendritic spine development (GO:0060998)2.73235198
128long-term synaptic potentiation (GO:0060291)2.72975701
129planar cell polarity pathway involved in neural tube closure (GO:0090179)2.71442769
130negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.71150239
131cardiac left ventricle morphogenesis (GO:0003214)2.70553286
132learning (GO:0007612)2.70191413
133negative regulation of synaptic transmission, GABAergic (GO:0032229)2.69580573
134regulation of neurotransmitter secretion (GO:0046928)2.69087123
135urinary tract smooth muscle contraction (GO:0014848)2.69049743
136neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.68694696
137negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.66089606
138regulation of synapse assembly (GO:0051963)2.64865494
139regulation of cAMP-dependent protein kinase activity (GO:2000479)2.64611138
140organelle transport along microtubule (GO:0072384)2.64149675
141regulation of glutamate secretion (GO:0014048)2.64071113
142regulation of synapse maturation (GO:0090128)2.63680232
143regulation of synapse organization (GO:0050807)2.62877136
144G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.62602573
145membrane depolarization (GO:0051899)2.62407013
146dendritic spine organization (GO:0097061)2.61483916
147vesicle transport along microtubule (GO:0047496)2.61234499
148G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.60346821
149axon extension (GO:0048675)2.60275295
150peptidyl-arginine methylation (GO:0018216)2.60187507
151negative regulation of striated muscle cell apoptotic process (GO:0010664)2.58123901
152ribonucleoprotein complex biogenesis (GO:0022613)2.57844582
153regulation of astrocyte differentiation (GO:0048710)2.53751029
154heart valve formation (GO:0003188)2.52747125
155histone H4-K12 acetylation (GO:0043983)2.51766876
156cell fate commitment involved in formation of primary germ layer (GO:0060795)2.51013777
157histone monoubiquitination (GO:0010390)2.50423570
158regulation of translational fidelity (GO:0006450)2.48354633
159atrial septum morphogenesis (GO:0060413)2.48213274
160forebrain neuron differentiation (GO:0021879)2.47889602
161neural precursor cell proliferation (GO:0061351)2.47865299
162mitochondrial respiratory chain complex assembly (GO:0033108)2.47235276
163mechanosensory behavior (GO:0007638)2.45275420
164axonemal dynein complex assembly (GO:0070286)2.43440602
165epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.42591217
166translation (GO:0006412)2.41616638
167cellular component biogenesis (GO:0044085)2.41564279
168apical protein localization (GO:0045176)2.41019763
169intraciliary transport (GO:0042073)2.40460151
170positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.39233190
171protein complex biogenesis (GO:0070271)2.38499862
172nuclear-transcribed mRNA catabolic process (GO:0000956)2.37463455
173positive regulation of potassium ion transmembrane transport (GO:1901381)2.34750317
174pattern specification involved in kidney development (GO:0061004)2.34182453
175regulation of vacuole organization (GO:0044088)2.31535409
176detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.29543594
177detection of temperature stimulus involved in sensory perception (GO:0050961)2.29543594
178cochlea development (GO:0090102)2.28561487
179mRNA catabolic process (GO:0006402)2.27998221
180regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.26078354
181DNA damage response, detection of DNA damage (GO:0042769)2.25716567
182protein localization to cilium (GO:0061512)2.24473021
183response to auditory stimulus (GO:0010996)2.22190645
184positive regulation of T cell apoptotic process (GO:0070234)2.22175118

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.15418367
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.18791714
3GBX2_23144817_ChIP-Seq_PC3_Human2.94510489
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.87294573
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.81408390
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.78843876
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.78811725
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.66296887
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.61527079
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.61009399
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.61009399
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.59539889
13MYC_18555785_ChIP-Seq_MESCs_Mouse2.58999465
14TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.40417726
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37116603
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35349715
17CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.33686058
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.33033825
19XRN2_22483619_ChIP-Seq_HELA_Human2.28507574
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.27644493
21* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22491038
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.21544136
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.17610624
24SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.14972121
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.14878720
26SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10621170
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.05180401
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.93602396
29THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92306884
30BMI1_23680149_ChIP-Seq_NPCS_Mouse1.90020592
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88508432
32POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88072154
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.86263011
34KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.84480782
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.82163702
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.81017547
37TAF15_26573619_Chip-Seq_HEK293_Human1.78597183
38SOX2_18555785_ChIP-Seq_MESCs_Mouse1.76055880
39TTF2_22483619_ChIP-Seq_HELA_Human1.75494094
40CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.73814941
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.73783457
42RNF2_27304074_Chip-Seq_NSC_Mouse1.70636131
43MYC_19079543_ChIP-ChIP_MESCs_Mouse1.69022191
44DROSHA_22980978_ChIP-Seq_HELA_Human1.68174832
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.67974909
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.66036168
47GATA1_26923725_Chip-Seq_HPCs_Mouse1.65104875
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.63747856
49ETS1_20019798_ChIP-Seq_JURKAT_Human1.63431770
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.63239683
51ZNF274_21170338_ChIP-Seq_K562_Hela1.62649981
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.62439003
53MYC_18358816_ChIP-ChIP_MESCs_Mouse1.58203850
54E2F7_22180533_ChIP-Seq_HELA_Human1.54650576
55* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.53877830
56AR_21572438_ChIP-Seq_LNCaP_Human1.52927787
57EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52793174
58MYC_19030024_ChIP-ChIP_MESCs_Mouse1.51504065
59TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.49731364
60RING1B_27294783_Chip-Seq_NPCs_Mouse1.47895806
61RING1B_27294783_Chip-Seq_ESCs_Mouse1.47520684
62ZFP281_18757296_ChIP-ChIP_E14_Mouse1.45214512
63JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.44655231
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.42902520
65* FUS_26573619_Chip-Seq_HEK293_Human1.42271955
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.41566420
67SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.38814012
68FOXM1_23109430_ChIP-Seq_U2OS_Human1.38129780
69RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.36957018
70* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.36301297
71CREB1_15753290_ChIP-ChIP_HEK293T_Human1.35877413
72SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.32940797
73SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.32622384
74YY1_21170310_ChIP-Seq_MESCs_Mouse1.32534219
75ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31194127
76* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29131946
77* VDR_22108803_ChIP-Seq_LS180_Human1.28199075
78SMAD4_21799915_ChIP-Seq_A2780_Human1.27295452
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25941977
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25477887
81MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25159680
82CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.24915183
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24577089
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.23755713
85NANOG_18555785_ChIP-Seq_MESCs_Mouse1.23537708
86* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.23155394
87TET1_21451524_ChIP-Seq_MESCs_Mouse1.22775733
88WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22730453
89SOX2_16153702_ChIP-ChIP_HESCs_Human1.21609717
90DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21380700
91P300_19829295_ChIP-Seq_ESCs_Human1.20826438
92OCT4_18692474_ChIP-Seq_MEFs_Mouse1.20212565
93SMAD3_21741376_ChIP-Seq_EPCs_Human1.19557671
94ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.19442231
95E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.16458798
96CTCF_27219007_Chip-Seq_Bcells_Human1.16280541
97TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.16105253
98POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.15583087
99SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15466624
100GABP_17652178_ChIP-ChIP_JURKAT_Human1.14904903
101SRY_22984422_ChIP-ChIP_TESTIS_Rat1.14459719
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14416179
103SOX2_18692474_ChIP-Seq_MEFs_Mouse1.14283492
104TP53_20018659_ChIP-ChIP_R1E_Mouse1.14125426
105SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.13682802
106E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10381932
107IGF1R_20145208_ChIP-Seq_DFB_Human1.10262453
108* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08930538
109GABP_19822575_ChIP-Seq_HepG2_Human1.08769636
110SOX2_21211035_ChIP-Seq_LN229_Gbm1.08730932
111TCF3_18692474_ChIP-Seq_MEFs_Mouse1.08701978
112THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08122496
113EST1_17652178_ChIP-ChIP_JURKAT_Human1.07507742
114SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07110989
115NELFA_20434984_ChIP-Seq_ESCs_Mouse1.05746754
116OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05307482
117PIAS1_25552417_ChIP-Seq_VCAP_Human1.04345697
118ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.04291138
119NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03244176
120CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.02697013
121POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01818388
122CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01713481
123KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.00994337
124AR_19668381_ChIP-Seq_PC3_Human1.00862913
125TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00366360
126POU5F1_16153702_ChIP-ChIP_HESCs_Human0.99182645
127SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98199303
128ZFP281_27345836_Chip-Seq_ESCs_Mouse0.97718218
129YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96684145
130OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96313373
131AR_25329375_ChIP-Seq_VCAP_Human0.96278711
132STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.95175378
133TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95124481
134POU3F2_20337985_ChIP-ChIP_501MEL_Human0.95107884
135NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.92376696
136P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91629725
137CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.91617604
138MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91131864
139POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90874095
140TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90874095
141KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.90613298
142KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.90613298
143KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.90613298
144JUN_21703547_ChIP-Seq_K562_Human0.90612799
145STAT3_23295773_ChIP-Seq_U87_Human0.89200559
146SMAD3_21741376_ChIP-Seq_ESCs_Human0.89178525
147RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.88652933
148CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88315280
149WT1_25993318_ChIP-Seq_PODOCYTE_Human0.87439217
150* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87209434
151KDM2B_26808549_Chip-Seq_K562_Human0.86156126
152POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.86035503
153DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85204361
154GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.83922572

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.78996347
2MP0003880_abnormal_central_pattern4.28405816
3MP0003635_abnormal_synaptic_transmissio3.49639131
4MP0004270_analgesia3.22108473
5MP0002063_abnormal_learning/memory/cond2.80240701
6MP0009745_abnormal_behavioral_response2.72550671
7MP0001968_abnormal_touch/_nociception2.57419344
8MP0005423_abnormal_somatic_nervous2.57139054
9MP0002064_seizures2.55149183
10MP0002734_abnormal_mechanical_nocicepti2.45418884
11MP0009046_muscle_twitch2.43338796
12MP0002572_abnormal_emotion/affect_behav2.38726929
13MP0003122_maternal_imprinting2.35723512
14MP0000778_abnormal_nervous_system2.34512008
15MP0006276_abnormal_autonomic_nervous2.31774070
16MP0001440_abnormal_grooming_behavior2.26859913
17MP0002272_abnormal_nervous_system2.21320436
18MP0002184_abnormal_innervation2.14253586
19MP0001486_abnormal_startle_reflex2.12811249
20MP0002733_abnormal_thermal_nociception2.03558609
21MP0002736_abnormal_nociception_after2.00614471
22MP0001501_abnormal_sleep_pattern1.82984698
23MP0001970_abnormal_pain_threshold1.81041053
24MP0002735_abnormal_chemical_nociception1.76725203
25MP0002067_abnormal_sensory_capabilities1.70438972
26MP0002557_abnormal_social/conspecific_i1.66140424
27MP0000955_abnormal_spinal_cord1.65603032
28MP0004924_abnormal_behavior1.62106990
29MP0005386_behavior/neurological_phenoty1.62106990
30MP0004185_abnormal_adipocyte_glucose1.62065181
31MP0001529_abnormal_vocalization1.61846866
32MP0004811_abnormal_neuron_physiology1.60141903
33MP0001188_hyperpigmentation1.59779957
34MP0003890_abnormal_embryonic-extraembry1.52051337
35MP0001984_abnormal_olfaction1.51907131
36MP0009053_abnormal_anal_canal1.51222672
37MP0002882_abnormal_neuron_morphology1.48622010
38MP0004145_abnormal_muscle_electrophysio1.46022191
39MP0001293_anophthalmia1.45639140
40MP0002909_abnormal_adrenal_gland1.40419002
41MP0001905_abnormal_dopamine_level1.40246468
42MP0002249_abnormal_larynx_morphology1.38930852
43MP0004858_abnormal_nervous_system1.37827071
44MP0004142_abnormal_muscle_tone1.37525425
45MP0002697_abnormal_eye_size1.34973363
46MP0002160_abnormal_reproductive_system1.33894817
47MP0002152_abnormal_brain_morphology1.33563191
48MP0002066_abnormal_motor_capabilities/c1.33473066
49MP0003937_abnormal_limbs/digits/tail_de1.33431604
50MP0005645_abnormal_hypothalamus_physiol1.32541349
51MP0006072_abnormal_retinal_apoptosis1.30594414
52MP0004885_abnormal_endolymph1.30195158
53MP0010030_abnormal_orbit_morphology1.29756834
54MP0001286_abnormal_eye_development1.27726820
55MP0003787_abnormal_imprinting1.27004810
56MP0003123_paternal_imprinting1.26954766
57MP0005623_abnormal_meninges_morphology1.25226913
58MP0000631_abnormal_neuroendocrine_gland1.22133628
59MP0002822_catalepsy1.19798064
60MP0000751_myopathy1.19662508
61MP0003121_genomic_imprinting1.17433885
62MP0005499_abnormal_olfactory_system1.17374813
63MP0005394_taste/olfaction_phenotype1.17374813
64MP0003329_amyloid_beta_deposits1.17063409
65MP0002163_abnormal_gland_morphology1.15709523
66MP0003878_abnormal_ear_physiology1.14595439
67MP0005377_hearing/vestibular/ear_phenot1.14595439
68MP0003861_abnormal_nervous_system1.14309328
69MP0008569_lethality_at_weaning1.14038708
70MP0001346_abnormal_lacrimal_gland1.13678679
71MP0006035_abnormal_mitochondrial_morpho1.13076039
72MP0008932_abnormal_embryonic_tissue1.10428861
73MP0002752_abnormal_somatic_nervous1.09664305
74MP0006292_abnormal_olfactory_placode1.08148459
75MP0005187_abnormal_penis_morphology1.06737908
76MP0009780_abnormal_chondrocyte_physiolo1.03111251
77MP0002638_abnormal_pupillary_reflex1.02979662
78MP0008007_abnormal_cellular_replicative1.02645015
79MP0003119_abnormal_digestive_system1.02114732
80MP0002653_abnormal_ependyma_morphology1.01499612
81MP0009250_abnormal_appendicular_skeleto1.00000066
82MP0004742_abnormal_vestibular_system0.99986365
83MP0002102_abnormal_ear_morphology0.99738017
84MP0003879_abnormal_hair_cell0.99582149
85MP0001485_abnormal_pinna_reflex0.99336708
86MP0003283_abnormal_digestive_organ0.98353502
87MP0003136_yellow_coat_color0.95721648
88MP0009379_abnormal_foot_pigmentation0.94655913
89MP0003938_abnormal_ear_development0.94295764
90MP0003755_abnormal_palate_morphology0.93239358
91MP0009672_abnormal_birth_weight0.92795570
92MP0001963_abnormal_hearing_physiology0.92635404
93MP0003385_abnormal_body_wall0.91969603
94MP0008789_abnormal_olfactory_epithelium0.91870814
95MP0002092_abnormal_eye_morphology0.91191428
96MP0003111_abnormal_nucleus_morphology0.90099446
97MP0002751_abnormal_autonomic_nervous0.89989019
98MP0002111_abnormal_tail_morphology0.89648288
99MP0004133_heterotaxia0.87978063
100MP0008877_abnormal_DNA_methylation0.87174239
101MP0005646_abnormal_pituitary_gland0.86959433
102MP0002938_white_spotting0.86830329
103MP0003693_abnormal_embryo_hatching0.85218070
104MP0001502_abnormal_circadian_rhythm0.83885816
105MP0002116_abnormal_craniofacial_bone0.83864254
106MP0003137_abnormal_impulse_conducting0.83260654
107MP0010386_abnormal_urinary_bladder0.81840865
108MP0004957_abnormal_blastocyst_morpholog0.81499606
109MP0004233_abnormal_muscle_weight0.80948530
110MP0000428_abnormal_craniofacial_morphol0.80845857
111MP0000762_abnormal_tongue_morphology0.80289146
112MP0005409_darkened_coat_color0.80218937
113MP0000537_abnormal_urethra_morphology0.79662062
114MP0002085_abnormal_embryonic_tissue0.79658140
115MP0000566_synostosis0.79197095
116MP0005551_abnormal_eye_electrophysiolog0.79051783
117MP0004085_abnormal_heartbeat0.77027398
118MP0003634_abnormal_glial_cell0.76949079
119MP0003077_abnormal_cell_cycle0.76440463
120MP0000026_abnormal_inner_ear0.76297418
121MP0002229_neurodegeneration0.76282797
122MP0002234_abnormal_pharynx_morphology0.72203588
123MP0003315_abnormal_perineum_morphology0.72200058
124MP0002837_dystrophic_cardiac_calcinosis0.70064002
125MP0002069_abnormal_eating/drinking_beha0.69866023
126MP0000534_abnormal_ureter_morphology0.68834937
127MP0001348_abnormal_lacrimal_gland0.68726939
128MP0000049_abnormal_middle_ear0.68614829
129MP0003633_abnormal_nervous_system0.68146513
130MP0003942_abnormal_urinary_system0.67689872
131MP0002081_perinatal_lethality0.66418818
132MP0001943_abnormal_respiration0.66272093
133MP0001299_abnormal_eye_distance/0.63687600

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.13311317
2Myokymia (HP:0002411)4.86958263
3Visual hallucinations (HP:0002367)4.79650774
4Focal seizures (HP:0007359)4.55823772
5Atonic seizures (HP:0010819)4.47978928
6Abnormality of cells of the erythroid lineage (HP:0012130)3.80464842
7Absence seizures (HP:0002121)3.79829821
8Epileptic encephalopathy (HP:0200134)3.74511692
9Limb dystonia (HP:0002451)3.69865659
10Reticulocytopenia (HP:0001896)3.58483885
11Abnormal number of incisors (HP:0011064)3.57845144
12Dialeptic seizures (HP:0011146)3.42793780
13Rib fusion (HP:0000902)3.36607475
14Septo-optic dysplasia (HP:0100842)3.33864370
15Febrile seizures (HP:0002373)3.32484023
16Macrocytic anemia (HP:0001972)3.30868047
17Aplasia/Hypoplasia of the sacrum (HP:0008517)3.28929670
18Amblyopia (HP:0000646)3.16293487
19Abnormal number of erythroid precursors (HP:0012131)3.05858536
20Abnormality of the labia minora (HP:0012880)3.05188501
21Broad-based gait (HP:0002136)2.96586741
22Progressive cerebellar ataxia (HP:0002073)2.95395182
23Generalized tonic-clonic seizures (HP:0002069)2.90630954
24Maternal diabetes (HP:0009800)2.82167794
25Broad distal phalanx of finger (HP:0009836)2.55274936
26Hyperventilation (HP:0002883)2.53605156
27Abnormal respiratory epithelium morphology (HP:0012253)2.52699760
28Abnormal respiratory motile cilium morphology (HP:0005938)2.52699760
29Amyotrophic lateral sclerosis (HP:0007354)2.52656153
30Missing ribs (HP:0000921)2.50912487
31Mutism (HP:0002300)2.47013205
32Termporal pattern (HP:0011008)2.44815631
33Insidious onset (HP:0003587)2.44815631
34Anophthalmia (HP:0000528)2.41512775
35Cerebral inclusion bodies (HP:0100314)2.38078588
36Sclerocornea (HP:0000647)2.35897990
37Supranuclear gaze palsy (HP:0000605)2.33666660
38Drooling (HP:0002307)2.31846163
39Excessive salivation (HP:0003781)2.31846163
40Hemiparesis (HP:0001269)2.30057931
41Agitation (HP:0000713)2.27492426
42Failure to thrive in infancy (HP:0001531)2.25393663
43Progressive inability to walk (HP:0002505)2.24097394
44Depression (HP:0000716)2.23152305
45Hyperthyroidism (HP:0000836)2.22417962
46Retinal dysplasia (HP:0007973)2.20845521
47Ankle clonus (HP:0011448)2.20567535
48Action tremor (HP:0002345)2.20385007
49Hypoventilation (HP:0002791)2.20304806
50Abnormal mitochondria in muscle tissue (HP:0008316)2.18909307
51Cortical dysplasia (HP:0002539)2.15754760
52Pallor (HP:0000980)2.15685871
53Epileptiform EEG discharges (HP:0011182)2.15617407
54Anxiety (HP:0000739)2.14867903
55Partial duplication of thumb phalanx (HP:0009944)2.14319923
56Abnormality of the corticospinal tract (HP:0002492)2.12465548
57EEG with generalized epileptiform discharges (HP:0011198)2.11137637
58Polyphagia (HP:0002591)2.08472325
59Poor eye contact (HP:0000817)2.08417502
60Truncal ataxia (HP:0002078)2.07707873
61Infantile muscular hypotonia (HP:0008947)2.07698016
62Deep palmar crease (HP:0006191)2.07566640
63Abnormal ventriculo-arterial connection (HP:0011563)2.07443954
64Transposition of the great arteries (HP:0001669)2.07443954
65Abnormal connection of the cardiac segments (HP:0011545)2.07443954
66Spastic diplegia (HP:0001264)2.06088014
67Abnormal eating behavior (HP:0100738)2.04861750
68Megalencephaly (HP:0001355)2.03157907
69Acute necrotizing encephalopathy (HP:0006965)2.03081869
70Aplasia/Hypoplasia of the brainstem (HP:0007362)2.02866847
71Hypoplasia of the brainstem (HP:0002365)2.02866847
7211 pairs of ribs (HP:0000878)1.99868720
73Hypsarrhythmia (HP:0002521)1.98067059
74Concave nail (HP:0001598)1.95883396
75Partial duplication of the phalanx of hand (HP:0009999)1.95839452
76Shoulder girdle muscle weakness (HP:0003547)1.95503110
77Narrow nasal bridge (HP:0000446)1.95167122
78Impaired vibration sensation in the lower limbs (HP:0002166)1.93923809
79Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.93793804
80Short 4th metacarpal (HP:0010044)1.93793804
81Dysmetria (HP:0001310)1.89797203
82Long palpebral fissure (HP:0000637)1.89030507
83Abnormal social behavior (HP:0012433)1.88373201
84Impaired social interactions (HP:0000735)1.88373201
85Facial hemangioma (HP:0000329)1.87753035
86Delusions (HP:0000746)1.87703452
87Dysdiadochokinesis (HP:0002075)1.87518533
88Generalized myoclonic seizures (HP:0002123)1.87111647
89Gait imbalance (HP:0002141)1.86309359
90Neurofibrillary tangles (HP:0002185)1.86041272
91Absent speech (HP:0001344)1.84594335
92Impulsivity (HP:0100710)1.83961341
93Sleep apnea (HP:0010535)1.83242446
94Lissencephaly (HP:0001339)1.83089509
95Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.81743754
96Achilles tendon contracture (HP:0001771)1.80882244
97Abnormality of the 4th metacarpal (HP:0010012)1.80465624
98Specific learning disability (HP:0001328)1.80242529
99Dysphonia (HP:0001618)1.80231915
100Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.79939063
101Obstructive sleep apnea (HP:0002870)1.79563342
102Acute encephalopathy (HP:0006846)1.79507681
103Papilledema (HP:0001085)1.79100423
104Abnormality of the lower motor neuron (HP:0002366)1.78579500
105Urinary urgency (HP:0000012)1.77579716
106Inability to walk (HP:0002540)1.77346573
107Short femoral neck (HP:0100864)1.77042876
108Decreased activity of mitochondrial respiratory chain (HP:0008972)1.77009512
109Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.77009512
110Hyperglycinemia (HP:0002154)1.76533779
111Buphthalmos (HP:0000557)1.76312856
112Urinary bladder sphincter dysfunction (HP:0002839)1.75960281
113Absent septum pellucidum (HP:0001331)1.75088748
114Hypogonadotrophic hypogonadism (HP:0000044)1.74902012
115Generalized hypotonia (HP:0001290)1.74517216
116Sporadic (HP:0003745)1.73108826
117Truncus arteriosus (HP:0001660)1.72297513
118Spastic gait (HP:0002064)1.72263352
119Abnormality of binocular vision (HP:0011514)1.72029535
120Diplopia (HP:0000651)1.72029535
121Pheochromocytoma (HP:0002666)1.71299305
122Cortical visual impairment (HP:0100704)1.71058083
123Absent/shortened dynein arms (HP:0200106)1.70769417
124Dynein arm defect of respiratory motile cilia (HP:0012255)1.70769417
125Hypoplasia of the radius (HP:0002984)1.70699965
126Gaze-evoked nystagmus (HP:0000640)1.70331274
127Rapidly progressive (HP:0003678)1.69987550
128Mesomelia (HP:0003027)1.69974288
129Fetal akinesia sequence (HP:0001989)1.69294638
130Supernumerary ribs (HP:0005815)1.68849702
131Esophageal atresia (HP:0002032)1.68078881
132Impaired smooth pursuit (HP:0007772)1.67269579
133Type II lissencephaly (HP:0007260)1.67177577
134Abdominal situs inversus (HP:0003363)1.67084938
135Abnormality of abdominal situs (HP:0011620)1.67084938
136Status epilepticus (HP:0002133)1.66735685
137Microretrognathia (HP:0000308)1.66548190
138Morphological abnormality of the pyramidal tract (HP:0002062)1.64552916
139Scanning speech (HP:0002168)1.64059755
140Restlessness (HP:0000711)1.63087417
141Supernumerary spleens (HP:0009799)1.62032953
142Spastic tetraplegia (HP:0002510)1.61250911
143Degeneration of the lateral corticospinal tracts (HP:0002314)1.60400803
144Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.60400803
145Torticollis (HP:0000473)1.60346895
146Radial bowing (HP:0002986)1.59891303
147Poor suck (HP:0002033)1.59551933
148Holoprosencephaly (HP:0001360)1.59151266
149Focal dystonia (HP:0004373)1.58924678
150Postural tremor (HP:0002174)1.58855734
151Annular pancreas (HP:0001734)1.58548747
152Atrioventricular canal defect (HP:0006695)1.58343013
153Exotropia (HP:0000577)1.58125137
154Lipid accumulation in hepatocytes (HP:0006561)1.57770321
155Colon cancer (HP:0003003)1.57567308
156Abnormality of the incisor (HP:0000676)1.56835214
157Hepatoblastoma (HP:0002884)1.56301305
158CNS hypomyelination (HP:0003429)1.55961046
159Patent foramen ovale (HP:0001655)1.55217057
160Horseshoe kidney (HP:0000085)1.54346564
161Arnold-Chiari malformation (HP:0002308)1.53948671
162Absent thumb (HP:0009777)1.53034143
163Increased intramyocellular lipid droplets (HP:0012240)1.52991379
164Hypoplastic left heart (HP:0004383)1.52376186
165Progressive macrocephaly (HP:0004481)1.52170382
166Diastasis recti (HP:0001540)1.51847015
167Supernumerary bones of the axial skeleton (HP:0009144)1.51557273
168Abnormality of the middle phalanges of the toes (HP:0010183)1.51049557
169Fibular hypoplasia (HP:0003038)1.50745323
170Humeroradial synostosis (HP:0003041)1.50458821
171Synostosis involving the elbow (HP:0003938)1.50458821

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.07664595
2MAP3K93.99599300
3PNCK3.96303307
4NTRK33.54107264
5TRIB33.33084160
6EPHA43.01869179
7MAP3K42.74574662
8MINK12.71469579
9LATS22.43922381
10STK162.39537251
11NTRK22.14675399
12MAP2K71.99177974
13CDC71.98408216
14PAK61.95116354
15CASK1.92645032
16MAP3K121.83282824
17NTRK11.81216450
18KSR21.77089653
19WEE11.72220585
20UHMK11.68410164
21VRK21.60844619
22TYRO31.59573457
23PLK21.58662535
24KSR11.57819148
25MAP2K41.57759346
26GRK51.54386666
27NME21.47378387
28DAPK21.47258778
29TAF11.40699401
30MAPK131.38874918
31IRAK21.35217616
32CDK51.33424445
33SIK21.32656488
34PHKG11.31580258
35PHKG21.31580258
36ARAF1.29480131
37CDK191.29033077
38DYRK31.27148906
39MAP3K111.18785521
40CSNK1G21.18721927
41MOS1.18419550
42DYRK21.17960588
43CAMKK21.16026106
44PAK31.15310510
45CDK141.13499362
46IRAK31.10145299
47PRKCG1.08686808
48VRK11.08225971
49PRKD31.07410048
50BRSK11.06510204
51DYRK1A1.05282545
52STK381.05189372
53DAPK11.04364272
54CAMK2A1.02233299
55BUB11.00583163
56CDK151.00335996
57NME11.00270615
58CDK180.98948063
59FGR0.98877012
60SMG10.97380111
61EIF2AK10.96738675
62CSNK1G30.93702444
63ILK0.93456712
64CDK11A0.91849201
65CAMKK10.91128695
66CHEK20.90455947
67ALK0.89900632
68PASK0.89630632
69DMPK0.88166776
70CAMK2B0.86468214
71TAOK20.85016243
72STK110.82465187
73CAMK1G0.82128692
74ICK0.81252982
75PLK10.80233130
76CAMK1D0.78890415
77WNK30.77685314
78FES0.77600424
79FER0.77188160
80DYRK1B0.76587391
81CSNK1G10.76001697
82MUSK0.71505124
83LRRK20.71122833
84DDR20.70757579
85MARK20.69418504
86RIPK40.69090012
87ABL20.68910039
88SCYL20.66384423
89PLK40.65234838
90WNK10.64239812
91CSNK1A1L0.63286595
92MAP3K60.62625343
93OXSR10.62079128
94MAP3K100.60783636
95CAMK10.60416245
96TNIK0.60273132
97CSNK1E0.60152122
98TESK20.59066844
99RET0.58958048
100BRSK20.57844819
101RAF10.56333603
102CDK30.55749982
103TTK0.55546521
104PTK2B0.55416320
105PLK30.54707050
106DAPK30.54518764
107MAPK150.54488297
108PRKCH0.54245236
109ROCK20.53148071
110MAP3K10.52883310
111AKT30.52750582
112PRPF4B0.51781697
113CAMK2D0.51457378
114MAPK100.51416736
115TSSK60.50626632
116PRKCZ0.46394487
117STK390.46078360
118LIMK10.43403635
119PRKCE0.43377918
120PKN10.43329380
121MAP3K20.42292864
122BCR0.42033496
123ADRBK10.40989083
124BRAF0.40947672
125AURKB0.39016878
126PRKCI0.38918525
127RPS6KA30.38472679
128CAMK2G0.38312644
129PIM20.37567304
130PDGFRA0.37513502
131TNK20.37072675
132RPS6KA20.36609190
133SGK10.35746982
134MAP2K10.34997612
135MKNK20.34789573
136ATR0.33923846
137EPHB20.33849164
138MAPK90.33725647
139CHEK10.32679475
140PINK10.32630398
141AURKA0.32196205
142WNK40.32175472
143CSNK2A20.31627484
144GSK3B0.31014363

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.94454370
2Nicotine addiction_Homo sapiens_hsa050333.60955950
3Synaptic vesicle cycle_Homo sapiens_hsa047212.79818127
4Sulfur relay system_Homo sapiens_hsa041222.59671518
5GABAergic synapse_Homo sapiens_hsa047272.55636911
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.47001819
7Long-term potentiation_Homo sapiens_hsa047202.41328206
8Olfactory transduction_Homo sapiens_hsa047402.40726663
9Circadian entrainment_Homo sapiens_hsa047132.31334663
10Amphetamine addiction_Homo sapiens_hsa050312.29888206
11Glutamatergic synapse_Homo sapiens_hsa047242.26147948
12Dopaminergic synapse_Homo sapiens_hsa047282.20260088
13Morphine addiction_Homo sapiens_hsa050322.18121333
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.09758372
15Taste transduction_Homo sapiens_hsa047421.84930505
16Long-term depression_Homo sapiens_hsa047301.84660755
17Serotonergic synapse_Homo sapiens_hsa047261.83670625
18Salivary secretion_Homo sapiens_hsa049701.79910632
19Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.74431717
20Cholinergic synapse_Homo sapiens_hsa047251.74370661
21Cocaine addiction_Homo sapiens_hsa050301.69649142
22Insulin secretion_Homo sapiens_hsa049111.68445198
23Gap junction_Homo sapiens_hsa045401.65973080
24Vitamin B6 metabolism_Homo sapiens_hsa007501.63822640
25Cardiac muscle contraction_Homo sapiens_hsa042601.62411810
26Oxidative phosphorylation_Homo sapiens_hsa001901.59392159
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59277280
28Renin secretion_Homo sapiens_hsa049241.56460705
29Gastric acid secretion_Homo sapiens_hsa049711.54163891
30Parkinsons disease_Homo sapiens_hsa050121.50268829
31Spliceosome_Homo sapiens_hsa030401.49276844
32Folate biosynthesis_Homo sapiens_hsa007901.49182317
33Oxytocin signaling pathway_Homo sapiens_hsa049211.48241307
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46808923
35Axon guidance_Homo sapiens_hsa043601.46633739
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.41948101
37Oocyte meiosis_Homo sapiens_hsa041141.41208800
38GnRH signaling pathway_Homo sapiens_hsa049121.40439645
39Fanconi anemia pathway_Homo sapiens_hsa034601.37665252
40Alzheimers disease_Homo sapiens_hsa050101.35211329
41Melanogenesis_Homo sapiens_hsa049161.33244114
42Estrogen signaling pathway_Homo sapiens_hsa049151.31506485
43Collecting duct acid secretion_Homo sapiens_hsa049661.30991606
44RNA polymerase_Homo sapiens_hsa030201.29329020
45Calcium signaling pathway_Homo sapiens_hsa040201.28497820
46Huntingtons disease_Homo sapiens_hsa050161.23065320
47Phototransduction_Homo sapiens_hsa047441.19023769
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15789201
49Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.11787861
50DNA replication_Homo sapiens_hsa030301.10613808
51Glioma_Homo sapiens_hsa052141.08784066
52cAMP signaling pathway_Homo sapiens_hsa040241.07943110
53ErbB signaling pathway_Homo sapiens_hsa040121.05442895
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04445965
55Hedgehog signaling pathway_Homo sapiens_hsa043401.03559216
56Vibrio cholerae infection_Homo sapiens_hsa051101.03541352
57Pyrimidine metabolism_Homo sapiens_hsa002401.02897435
58Steroid biosynthesis_Homo sapiens_hsa001000.97609380
59Notch signaling pathway_Homo sapiens_hsa043300.94446259
60Cell cycle_Homo sapiens_hsa041100.94246029
61Wnt signaling pathway_Homo sapiens_hsa043100.93569323
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92812081
63Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.92788663
64Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.92699025
65Alcoholism_Homo sapiens_hsa050340.92644118
66Dorso-ventral axis formation_Homo sapiens_hsa043200.89037584
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.88546360
68TGF-beta signaling pathway_Homo sapiens_hsa043500.87886760
69Renal cell carcinoma_Homo sapiens_hsa052110.85819580
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.85777946
71Pyruvate metabolism_Homo sapiens_hsa006200.83668311
72Choline metabolism in cancer_Homo sapiens_hsa052310.83537070
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79969015
74Selenocompound metabolism_Homo sapiens_hsa004500.79744725
75Protein export_Homo sapiens_hsa030600.79583853
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79402228
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.77994963
78RNA degradation_Homo sapiens_hsa030180.77013340
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76958031
80MAPK signaling pathway_Homo sapiens_hsa040100.74667797
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74428423
82Type II diabetes mellitus_Homo sapiens_hsa049300.72309859
83Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71168630
84Hippo signaling pathway_Homo sapiens_hsa043900.70935945
85Dilated cardiomyopathy_Homo sapiens_hsa054140.68888178
86RNA transport_Homo sapiens_hsa030130.68331523
87Ras signaling pathway_Homo sapiens_hsa040140.66707366
88One carbon pool by folate_Homo sapiens_hsa006700.66317239
89Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66267496
90mRNA surveillance pathway_Homo sapiens_hsa030150.64411252
91mTOR signaling pathway_Homo sapiens_hsa041500.62617296
92Bladder cancer_Homo sapiens_hsa052190.62512614
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62083724
94Colorectal cancer_Homo sapiens_hsa052100.61574095
95VEGF signaling pathway_Homo sapiens_hsa043700.61059384
96Thyroid hormone synthesis_Homo sapiens_hsa049180.59213063
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59140720
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.58737267
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57692359
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.57327346
101Rap1 signaling pathway_Homo sapiens_hsa040150.56833368
102Pancreatic secretion_Homo sapiens_hsa049720.56530000
103Central carbon metabolism in cancer_Homo sapiens_hsa052300.56195937
104Basal cell carcinoma_Homo sapiens_hsa052170.54997251
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54051772
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53165203
107Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53076442
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52622476
109Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52495304
110Endometrial cancer_Homo sapiens_hsa052130.51837532
111Tight junction_Homo sapiens_hsa045300.51629431
112Chronic myeloid leukemia_Homo sapiens_hsa052200.51299286
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50382630
114Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50275090
115Base excision repair_Homo sapiens_hsa034100.49688551
116Nucleotide excision repair_Homo sapiens_hsa034200.49125249
117MicroRNAs in cancer_Homo sapiens_hsa052060.48956623
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47173336
119Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.47125184
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46327813
121Glucagon signaling pathway_Homo sapiens_hsa049220.46308406
122Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45894954
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.45815733
124Prion diseases_Homo sapiens_hsa050200.45055514
125Melanoma_Homo sapiens_hsa052180.44877745
126Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.42583748
127Basal transcription factors_Homo sapiens_hsa030220.41937904
128Endocytosis_Homo sapiens_hsa041440.41861663
129Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41167962
130N-Glycan biosynthesis_Homo sapiens_hsa005100.40816183
131p53 signaling pathway_Homo sapiens_hsa041150.40236351
132Insulin signaling pathway_Homo sapiens_hsa049100.39554510
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38572907
134Ovarian steroidogenesis_Homo sapiens_hsa049130.33215635
135Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.32162396
136Non-small cell lung cancer_Homo sapiens_hsa052230.31010693
137Regulation of actin cytoskeleton_Homo sapiens_hsa048100.30132079

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