EID2B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.34366276
2synaptic vesicle maturation (GO:0016188)5.29794662
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.29455274
4behavioral response to nicotine (GO:0035095)5.25346219
5synaptic vesicle exocytosis (GO:0016079)5.00707325
6neuron recognition (GO:0008038)4.90325017
7locomotory exploration behavior (GO:0035641)4.84613855
8neuron cell-cell adhesion (GO:0007158)4.82636981
9protein localization to synapse (GO:0035418)4.75537435
10vocalization behavior (GO:0071625)4.66485523
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.64585861
12layer formation in cerebral cortex (GO:0021819)4.47787241
13glutamate secretion (GO:0014047)4.43959706
14dendritic spine morphogenesis (GO:0060997)4.43827114
15pyrimidine nucleobase catabolic process (GO:0006208)4.40132369
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.29771982
17regulation of glutamate receptor signaling pathway (GO:1900449)4.27677078
18axonal fasciculation (GO:0007413)4.25549420
19DNA deamination (GO:0045006)4.23920198
20regulation of synaptic vesicle exocytosis (GO:2000300)4.22896670
21exploration behavior (GO:0035640)4.18770976
22response to pheromone (GO:0019236)4.07378155
23respiratory chain complex IV assembly (GO:0008535)4.07325772
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.04192356
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.04192356
26NADH dehydrogenase complex assembly (GO:0010257)4.04192356
27protein complex biogenesis (GO:0070271)3.99258399
28negative regulation of microtubule polymerization (GO:0031115)3.98703378
29negative regulation of mast cell activation (GO:0033004)3.95460538
30regulation of synapse structural plasticity (GO:0051823)3.92354525
31ionotropic glutamate receptor signaling pathway (GO:0035235)3.90038636
32regulation of long-term neuronal synaptic plasticity (GO:0048169)3.89316919
33neurotransmitter secretion (GO:0007269)3.87207359
34regulation of synaptic vesicle transport (GO:1902803)3.82591592
35mitochondrial respiratory chain complex assembly (GO:0033108)3.70678935
36dendrite morphogenesis (GO:0048813)3.70636899
37regulation of neuronal synaptic plasticity (GO:0048168)3.67660986
38protein polyglutamylation (GO:0018095)3.67458049
39activation of protein kinase A activity (GO:0034199)3.66511800
40neuronal action potential propagation (GO:0019227)3.55390401
41protein-cofactor linkage (GO:0018065)3.55256603
42cytochrome complex assembly (GO:0017004)3.54490818
43synaptic vesicle docking involved in exocytosis (GO:0016081)3.53001047
44mating behavior (GO:0007617)3.51908475
45fucose catabolic process (GO:0019317)3.51703456
46L-fucose metabolic process (GO:0042354)3.51703456
47L-fucose catabolic process (GO:0042355)3.51703456
48glutamate receptor signaling pathway (GO:0007215)3.50791384
49negative regulation of transcription regulatory region DNA binding (GO:2000678)3.50748990
50nucleobase catabolic process (GO:0046113)3.45350343
51positive regulation of synapse maturation (GO:0090129)3.39075824
52central nervous system projection neuron axonogenesis (GO:0021952)3.38486035
53regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.38030245
54positive regulation of dendritic spine development (GO:0060999)3.36329318
55preassembly of GPI anchor in ER membrane (GO:0016254)3.35955072
56behavioral defense response (GO:0002209)3.34994582
57behavioral fear response (GO:0001662)3.34994582
58cell migration in hindbrain (GO:0021535)3.34606580
59neurotransmitter-gated ion channel clustering (GO:0072578)3.34214371
60water-soluble vitamin biosynthetic process (GO:0042364)3.32365811
61synaptic transmission, glutamatergic (GO:0035249)3.27686814
62long-term memory (GO:0007616)3.26009293
63magnesium ion transport (GO:0015693)3.21750532
64regulation of cilium movement (GO:0003352)3.21653872
65axoneme assembly (GO:0035082)3.17588212
66positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.16488107
67adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.15984618
68dopamine receptor signaling pathway (GO:0007212)3.15060869
69neuron-neuron synaptic transmission (GO:0007270)3.14316604
70positive regulation of membrane potential (GO:0045838)3.13244992
71positive regulation of cell fate commitment (GO:0010455)3.13196537
72auditory behavior (GO:0031223)3.13142096
73neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.12725191
74fear response (GO:0042596)3.10849596
75ubiquinone biosynthetic process (GO:0006744)3.09977665
76regulation of vesicle fusion (GO:0031338)3.09656502
77regulation of excitatory postsynaptic membrane potential (GO:0060079)3.07962472
78positive regulation of synapse assembly (GO:0051965)3.07478741
79regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.06298434
80neurotransmitter transport (GO:0006836)3.04207148
81detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.03048673
82regulation of postsynaptic membrane potential (GO:0060078)3.02794529
83negative regulation of telomere maintenance (GO:0032205)3.00735477
84negative regulation of calcium ion transport into cytosol (GO:0010523)3.00709557
85ubiquinone metabolic process (GO:0006743)2.99380100
86positive regulation of dendritic spine morphogenesis (GO:0061003)2.98831843
87mannosylation (GO:0097502)2.98603234
88epithelial cilium movement (GO:0003351)2.97981687
89regulation of dendritic spine morphogenesis (GO:0061001)2.97286428
90dendritic spine organization (GO:0097061)2.94462661
91proline transport (GO:0015824)2.92912794
92synapse assembly (GO:0007416)2.92244580
93intra-S DNA damage checkpoint (GO:0031573)2.92089383
94positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.92077963
95transmission of nerve impulse (GO:0019226)2.91681525
96nonmotile primary cilium assembly (GO:0035058)2.90257153
97mechanosensory behavior (GO:0007638)2.89400313
98cerebellum development (GO:0021549)2.88698296
99cerebellar Purkinje cell layer development (GO:0021680)2.88053794
100neuronal action potential (GO:0019228)2.87919897
101epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.87484679
102regulation of neurotransmitter levels (GO:0001505)2.85913072
103ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.84693524
104dendrite development (GO:0016358)2.84096616
105cornea development in camera-type eye (GO:0061303)2.83474954
106membrane hyperpolarization (GO:0060081)2.83038425
107response to auditory stimulus (GO:0010996)2.82849894
108gamma-aminobutyric acid transport (GO:0015812)2.82667889
109regulation of synaptic plasticity (GO:0048167)2.82206032
110iron-sulfur cluster assembly (GO:0016226)2.81947830
111metallo-sulfur cluster assembly (GO:0031163)2.81947830
112postsynaptic membrane organization (GO:0001941)2.81941251
113regulation of cAMP-dependent protein kinase activity (GO:2000479)2.80970051
114negative regulation of synaptic transmission, GABAergic (GO:0032229)2.80854284
115hippocampus development (GO:0021766)2.79883322
116mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.79219003
117cerebral cortex neuron differentiation (GO:0021895)2.78036053
118cellular response to glucagon stimulus (GO:0071377)2.76436640
119mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.75566664
120positive regulation of synaptic transmission, GABAergic (GO:0032230)2.75160722
121membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.74285420
122somatic hypermutation of immunoglobulin genes (GO:0016446)2.73780420
123somatic diversification of immune receptors via somatic mutation (GO:0002566)2.73780420
124synapse organization (GO:0050808)2.73095403
125axon extension (GO:0048675)2.72723399
126long-term synaptic potentiation (GO:0060291)2.70147294
127vesicle transport along microtubule (GO:0047496)2.70128489
128G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.69895401
129sulfation (GO:0051923)2.68631671
130organelle transport along microtubule (GO:0072384)2.68239900
131regulation of memory T cell differentiation (GO:0043380)2.68223910
132regulation of dendritic spine development (GO:0060998)2.67686699
133negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.67580160
134regulation of microtubule-based movement (GO:0060632)2.67483275
135innervation (GO:0060384)2.67192639
136axon cargo transport (GO:0008088)2.66934745
137regulation of synaptic transmission, glutamatergic (GO:0051966)2.66929478
138energy coupled proton transport, down electrochemical gradient (GO:0015985)2.66067714
139ATP synthesis coupled proton transport (GO:0015986)2.66067714
140regulation of neurotransmitter secretion (GO:0046928)2.66015394
141detection of calcium ion (GO:0005513)2.65851064
142cerebral cortex radially oriented cell migration (GO:0021799)2.65317839
143membrane depolarization (GO:0051899)2.65011504
144piRNA metabolic process (GO:0034587)2.62489914
145regulation of nuclear cell cycle DNA replication (GO:0033262)2.61355733
146retinal ganglion cell axon guidance (GO:0031290)2.60818544
147synaptic transmission, cholinergic (GO:0007271)2.60521017
148hindbrain development (GO:0030902)2.59727454
149pseudouridine synthesis (GO:0001522)2.58893203
150cellular ketone body metabolic process (GO:0046950)2.56278475
151GPI anchor metabolic process (GO:0006505)2.56082735
152regulation of mesoderm development (GO:2000380)2.55890241
153indolalkylamine metabolic process (GO:0006586)2.54831680
154positive regulation of mitochondrial fission (GO:0090141)2.54805343
155positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.54753602
156nephron tubule morphogenesis (GO:0072078)2.54179995
157nephron epithelium morphogenesis (GO:0072088)2.54179995
158protein localization to cilium (GO:0061512)2.53964092
159regulation of respiratory system process (GO:0044065)2.53859436
160rhodopsin mediated signaling pathway (GO:0016056)2.50770552
161L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.50313595
162neuron fate determination (GO:0048664)2.49571556
163regulation of neurotransmitter uptake (GO:0051580)2.48774701
164regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.48341495
165tRNA modification (GO:0006400)2.47330071
166DNA methylation involved in gamete generation (GO:0043046)2.46807629
167behavioral response to ethanol (GO:0048149)2.46069563
168primary amino compound metabolic process (GO:1901160)2.45649616
169mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.44748498
170regulation of rhodopsin mediated signaling pathway (GO:0022400)2.44234288
171regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.43965369
172negative regulation of membrane potential (GO:0045837)2.43318594
173regulation of action potential (GO:0098900)2.42437649
174regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.42122301
175positive regulation of prostaglandin secretion (GO:0032308)2.40012126
176platelet dense granule organization (GO:0060155)2.39368573
177cilium organization (GO:0044782)2.37520073
178membrane depolarization during action potential (GO:0086010)2.37152117
179tRNA processing (GO:0008033)2.35948189
180reciprocal DNA recombination (GO:0035825)2.34250036
181reciprocal meiotic recombination (GO:0007131)2.34250036
182positive regulation of defense response to virus by host (GO:0002230)2.34079597
183ketone body metabolic process (GO:1902224)2.33320648
184kynurenine metabolic process (GO:0070189)2.33069503
185ATP biosynthetic process (GO:0006754)2.32297557
186cilium morphogenesis (GO:0060271)2.31944870

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.78367233
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.20823217
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.05692827
4REST_21632747_ChIP-Seq_MESCs_Mouse3.02688714
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.99358261
6NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.98215731
7GBX2_23144817_ChIP-Seq_PC3_Human2.90793086
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.88253432
9* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.85052955
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.75849954
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.62624703
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.61067134
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.61067134
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58357257
15RARB_27405468_Chip-Seq_BRAIN_Mouse2.57739094
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.57631702
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.54752021
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50994371
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.50746985
20REST_18959480_ChIP-ChIP_MESCs_Mouse2.47621141
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.45733560
22GABP_17652178_ChIP-ChIP_JURKAT_Human2.31446480
23EED_16625203_ChIP-ChIP_MESCs_Mouse2.31111113
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.29455317
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.25686237
26TAF15_26573619_Chip-Seq_HEK293_Human2.25088662
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.22952487
28ZNF263_19887448_ChIP-Seq_K562_Human2.19124067
29ZNF274_21170338_ChIP-Seq_K562_Hela2.17926578
30KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.09299951
31DROSHA_22980978_ChIP-Seq_HELA_Human2.07501241
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96565096
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.93157472
34NOTCH1_21737748_ChIP-Seq_TLL_Human1.90364082
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.90334012
36EWS_26573619_Chip-Seq_HEK293_Human1.84002539
37EST1_17652178_ChIP-ChIP_JURKAT_Human1.81402642
38PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.79048610
39MYC_18940864_ChIP-ChIP_HL60_Human1.77996569
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74615324
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73942665
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73281076
43CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71541580
44ERG_21242973_ChIP-ChIP_JURKAT_Human1.70203292
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.70179583
46EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.69413161
47IRF1_19129219_ChIP-ChIP_H3396_Human1.65777540
48EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65038066
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.64487112
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.63609655
51JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.60818784
52FUS_26573619_Chip-Seq_HEK293_Human1.59511716
53TP53_22573176_ChIP-Seq_HFKS_Human1.57907535
54ZFP281_18757296_ChIP-ChIP_E14_Mouse1.57035286
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.56996539
56AR_21572438_ChIP-Seq_LNCaP_Human1.55526698
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.54950427
58ETS1_20019798_ChIP-Seq_JURKAT_Human1.54212529
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53830056
60DNAJC2_21179169_ChIP-ChIP_NT2_Human1.50887850
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.47119601
62RNF2_27304074_Chip-Seq_NSC_Mouse1.42671182
63VDR_23849224_ChIP-Seq_CD4+_Human1.42202203
64ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.42099135
65IGF1R_20145208_ChIP-Seq_DFB_Human1.40084083
66WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.38146383
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36456176
68PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.36315730
69RING1B_27294783_Chip-Seq_NPCs_Mouse1.35939671
70RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.34001076
71E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.33904782
72ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33790870
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.31900268
74RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30490368
75OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29428149
76SRF_21415370_ChIP-Seq_HL-1_Mouse1.28462660
77NCOR_22424771_ChIP-Seq_293T_Human1.25310094
78CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.23561200
79TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.22572623
80* FOXA1_25329375_ChIP-Seq_VCAP_Human1.22558928
81* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.22558928
82VDR_22108803_ChIP-Seq_LS180_Human1.21042687
83P300_19829295_ChIP-Seq_ESCs_Human1.19715608
84EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.19390244
85GATA3_21878914_ChIP-Seq_MCF-7_Human1.18553957
86CBP_20019798_ChIP-Seq_JUKART_Human1.18319809
87IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18319809
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.17749928
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17507598
90TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16873325
91POU5F1_16153702_ChIP-ChIP_HESCs_Human1.16695598
92SMAD4_21799915_ChIP-Seq_A2780_Human1.16184791
93CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14298943
94UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13419649
95STAT3_23295773_ChIP-Seq_U87_Human1.12509082
96GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09522625
97P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09482547
98OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09101577
99NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09062816
100TP53_20018659_ChIP-ChIP_R1E_Mouse1.08039630
101HOXB7_26014856_ChIP-Seq_BT474_Human1.07759055
102SALL1_21062744_ChIP-ChIP_HESCs_Human1.07678160
103PCGF2_27294783_Chip-Seq_ESCs_Mouse1.07015437
104SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04814822
105SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.04426591
106TCF4_23295773_ChIP-Seq_U87_Human1.03532428
107TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02144507
108AR_19668381_ChIP-Seq_PC3_Human1.01839507
109PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.00953702
110KDM2B_26808549_Chip-Seq_K562_Human0.99865402
111FLI1_21867929_ChIP-Seq_TH2_Mouse0.99677928
112ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99087971
113KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97673813
114NANOG_19829295_ChIP-Seq_ESCs_Human0.97547085
115SOX2_19829295_ChIP-Seq_ESCs_Human0.97547085
116FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.97194620
117ERA_21632823_ChIP-Seq_H3396_Human0.96454438
118GATA1_26923725_Chip-Seq_HPCs_Mouse0.96308435
119TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96108107
120SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96005772
121CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95540260
122SMAD3_21741376_ChIP-Seq_EPCs_Human0.94700038
123ELK1_19687146_ChIP-ChIP_HELA_Human0.94188551
124MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94183466
125GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94012293
126MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.93981320
127FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93512068
128YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93462348
129AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.93338556
130TCF4_22108803_ChIP-Seq_LS180_Human0.93133052
131WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93064049
132PIAS1_25552417_ChIP-Seq_VCAP_Human0.92856408
133PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.92654781
134AR_25329375_ChIP-Seq_VCAP_Human0.92101802
135SMAD3_21741376_ChIP-Seq_ESCs_Human0.91739807
136SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91272736
137TET1_21490601_ChIP-Seq_MESCs_Mouse0.91212926
138ZFP281_27345836_Chip-Seq_ESCs_Mouse0.90026923
139CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86295804
140BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.83692626
141PRDM14_20953172_ChIP-Seq_ESCs_Human0.81295330
142REST_19997604_ChIP-ChIP_NEURONS_Mouse0.81159081
143CTCF_27219007_Chip-Seq_Bcells_Human0.80061954
144SMAD4_21741376_ChIP-Seq_HESCs_Human0.79445804
145GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.79212468
146ER_23166858_ChIP-Seq_MCF-7_Human0.78953058
147SOX3_22085726_ChIP-Seq_NPCs_Mouse0.77130482
148ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.77005761
149FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.76149645
150TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75889929
151POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.75889929
152ELK4_26923725_Chip-Seq_MESODERM_Mouse0.75451852
153RUNX2_22187159_ChIP-Seq_PCA_Human0.75399932
154POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.74114264
155KDM2B_26808549_Chip-Seq_SUP-B15_Human0.72616731

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.52013688
2MP0003880_abnormal_central_pattern5.03316696
3MP0003635_abnormal_synaptic_transmissio3.68388469
4MP0004270_analgesia3.12471696
5MP0002063_abnormal_learning/memory/cond3.08585345
6MP0005423_abnormal_somatic_nervous2.99026200
7MP0006276_abnormal_autonomic_nervous2.88714549
8MP0002102_abnormal_ear_morphology2.72665127
9MP0008877_abnormal_DNA_methylation2.70336203
10MP0009745_abnormal_behavioral_response2.70287936
11MP0002064_seizures2.55093807
12MP0001968_abnormal_touch/_nociception2.55015618
13MP0000778_abnormal_nervous_system2.45353594
14MP0002572_abnormal_emotion/affect_behav2.43733597
15MP0004147_increased_porphyrin_level2.42042921
16MP0002734_abnormal_mechanical_nocicepti2.24686850
17MP0003122_maternal_imprinting2.22471872
18MP0003329_amyloid_beta_deposits2.19357597
19MP0006292_abnormal_olfactory_placode2.18966853
20MP0003195_calcinosis2.16723377
21MP0001486_abnormal_startle_reflex2.14882996
22MP0002184_abnormal_innervation2.14704671
23MP0002733_abnormal_thermal_nociception2.12442276
24MP0008872_abnormal_physiological_respon2.10818027
25MP0002272_abnormal_nervous_system2.04603682
26MP0008961_abnormal_basal_metabolism1.97565305
27MP0005645_abnormal_hypothalamus_physiol1.96657132
28MP0009046_muscle_twitch1.96302633
29MP0001440_abnormal_grooming_behavior1.95265071
30MP0002909_abnormal_adrenal_gland1.88512403
31MP0001529_abnormal_vocalization1.88195876
32MP0002837_dystrophic_cardiac_calcinosis1.85589503
33MP0001970_abnormal_pain_threshold1.84838166
34MP0002557_abnormal_social/conspecific_i1.84667902
35MP0004811_abnormal_neuron_physiology1.84017686
36MP0002735_abnormal_chemical_nociception1.83287313
37MP0002736_abnormal_nociception_after1.77549354
38MP0001984_abnormal_olfaction1.76427839
39MP0000955_abnormal_spinal_cord1.72370721
40MP0002822_catalepsy1.66682029
41MP0001188_hyperpigmentation1.60532867
42MP0000751_myopathy1.60008193
43MP0002067_abnormal_sensory_capabilities1.59992510
44MP0005646_abnormal_pituitary_gland1.54714569
45MP0000569_abnormal_digit_pigmentation1.52871245
46MP0005084_abnormal_gallbladder_morpholo1.52047933
47MP0002882_abnormal_neuron_morphology1.51351328
48MP0001986_abnormal_taste_sensitivity1.48108675
49MP0006072_abnormal_retinal_apoptosis1.47445053
50MP0004924_abnormal_behavior1.46546636
51MP0005386_behavior/neurological_phenoty1.46546636
52MP0002160_abnormal_reproductive_system1.44639875
53MP0004142_abnormal_muscle_tone1.42296058
54MP0001502_abnormal_circadian_rhythm1.41376668
55MP0003646_muscle_fatigue1.38553456
56MP0001905_abnormal_dopamine_level1.38228875
57MP0008569_lethality_at_weaning1.35327244
58MP0001485_abnormal_pinna_reflex1.34208484
59MP0008995_early_reproductive_senescence1.33686793
60MP0004858_abnormal_nervous_system1.31994651
61MP0002066_abnormal_motor_capabilities/c1.31168367
62MP0002089_abnormal_postnatal_growth/wei1.29269366
63MP0000013_abnormal_adipose_tissue1.28245042
64MP0008875_abnormal_xenobiotic_pharmacok1.26442050
65MP0000631_abnormal_neuroendocrine_gland1.25095873
66MP0002152_abnormal_brain_morphology1.24030690
67MP0002876_abnormal_thyroid_physiology1.23045887
68MP0005389_reproductive_system_phenotype1.19629214
69MP0002638_abnormal_pupillary_reflex1.18281105
70MP0004145_abnormal_muscle_electrophysio1.17421506
71MP0001501_abnormal_sleep_pattern1.17405871
72MP0005394_taste/olfaction_phenotype1.15021838
73MP0005499_abnormal_olfactory_system1.15021838
74MP0001919_abnormal_reproductive_system1.14947155
75MP0004885_abnormal_endolymph1.13041797
76MP0000026_abnormal_inner_ear1.11277047
77MP0004043_abnormal_pH_regulation1.09028617
78MP0003938_abnormal_ear_development1.08784075
79MP0003787_abnormal_imprinting1.08682862
80MP0005551_abnormal_eye_electrophysiolog1.08440334
81MP0003011_delayed_dark_adaptation1.07465865
82MP0002938_white_spotting1.04908674
83MP0002069_abnormal_eating/drinking_beha1.04837982
84MP0002277_abnormal_respiratory_mucosa0.98914474
85MP0003137_abnormal_impulse_conducting0.98636500
86MP0009379_abnormal_foot_pigmentation0.98226059
87MP0002928_abnormal_bile_duct0.97815683
88MP0003879_abnormal_hair_cell0.97618292
89MP0002752_abnormal_somatic_nervous0.96797174
90MP0009780_abnormal_chondrocyte_physiolo0.95962083
91MP0008789_abnormal_olfactory_epithelium0.95638755
92MP0004215_abnormal_myocardial_fiber0.94734702
93MP0005409_darkened_coat_color0.94539436
94MP0003136_yellow_coat_color0.94113869
95MP0003121_genomic_imprinting0.93566757
96MP0003861_abnormal_nervous_system0.91333671
97MP0008058_abnormal_DNA_repair0.90061424
98MP0001764_abnormal_homeostasis0.89136283
99MP0005535_abnormal_body_temperature0.88404162
100MP0002090_abnormal_vision0.88081299
101MP0005195_abnormal_posterior_eye0.87855371
102MP0004133_heterotaxia0.87748153
103MP0004085_abnormal_heartbeat0.87476908
104MP0000681_abnormal_thyroid_gland0.86087472
105MP0002751_abnormal_autonomic_nervous0.85134374
106MP0005253_abnormal_eye_physiology0.83952435
107MP0000427_abnormal_hair_cycle0.83891144
108MP0003119_abnormal_digestive_system0.81670024
109MP0000604_amyloidosis0.80206092
110MP0003698_abnormal_male_reproductive0.80095792
111MP0002229_neurodegeneration0.79127182
112MP0003634_abnormal_glial_cell0.78604295
113MP0001664_abnormal_digestion0.78069166
114MP0002653_abnormal_ependyma_morphology0.77494838
115MP0005187_abnormal_penis_morphology0.77180096
116MP0008775_abnormal_heart_ventricle0.73470667
117MP0003633_abnormal_nervous_system0.72944499
118MP0001943_abnormal_respiration0.71123858
119MP0000049_abnormal_middle_ear0.70691805
120MP0004233_abnormal_muscle_weight0.68665807
121MP0002234_abnormal_pharynx_morphology0.68320930
122MP0003631_nervous_system_phenotype0.67133937
123MP0004742_abnormal_vestibular_system0.64718823
124MP0002177_abnormal_outer_ear0.63510041
125MP0000372_irregular_coat_pigmentation0.62464542
126MP0005075_abnormal_melanosome_morpholog0.61751947
127MP0005248_abnormal_Harderian_gland0.60888131
128MP0004130_abnormal_muscle_cell0.60021416
129MP0010386_abnormal_urinary_bladder0.59817805
130MP0001963_abnormal_hearing_physiology0.56016739
131MP0002081_perinatal_lethality0.54848193

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.29041955
2Focal motor seizures (HP:0011153)5.15664020
3Visual hallucinations (HP:0002367)4.85681544
4Focal seizures (HP:0007359)4.10188339
5Mutism (HP:0002300)4.06960291
6Type II lissencephaly (HP:0007260)3.88546965
7Epileptic encephalopathy (HP:0200134)3.78313127
8Abnormality of midbrain morphology (HP:0002418)3.62840851
9Molar tooth sign on MRI (HP:0002419)3.62840851
10Ankle clonus (HP:0011448)3.62838347
11Agitation (HP:0000713)3.59380669
12Polyphagia (HP:0002591)3.49246706
13Limb dystonia (HP:0002451)3.45518830
14Pancreatic cysts (HP:0001737)3.44444782
15Progressive cerebellar ataxia (HP:0002073)3.40766295
16Nephronophthisis (HP:0000090)3.32549373
17Broad-based gait (HP:0002136)3.31211846
18Pancreatic fibrosis (HP:0100732)3.29233841
19Papilledema (HP:0001085)3.28320737
20Amyotrophic lateral sclerosis (HP:0007354)3.25330892
21Poor eye contact (HP:0000817)3.23432137
22Congenital stationary night blindness (HP:0007642)3.21387960
23Failure to thrive in infancy (HP:0001531)3.13009037
24Abnormal drinking behavior (HP:0030082)3.09671413
25Polydipsia (HP:0001959)3.09671413
26True hermaphroditism (HP:0010459)3.06456697
27Febrile seizures (HP:0002373)3.04930955
28Truncal ataxia (HP:0002078)3.01902678
29Anxiety (HP:0000739)3.01785338
30Depression (HP:0000716)3.00887715
31Supranuclear gaze palsy (HP:0000605)3.00401247
32Excessive salivation (HP:0003781)2.99909140
33Drooling (HP:0002307)2.99909140
34Mitochondrial inheritance (HP:0001427)2.99102945
35Impaired vibration sensation in the lower limbs (HP:0002166)2.97438335
36Abnormal eating behavior (HP:0100738)2.91798518
37Hyperventilation (HP:0002883)2.87937915
38Progressive inability to walk (HP:0002505)2.84824205
39Generalized tonic-clonic seizures (HP:0002069)2.83369434
40Impaired social interactions (HP:0000735)2.83357173
41Abnormal social behavior (HP:0012433)2.83357173
42Large for gestational age (HP:0001520)2.78512581
43Hepatic necrosis (HP:0002605)2.66961887
44Increased CSF lactate (HP:0002490)2.66522363
45Amblyopia (HP:0000646)2.59365516
46Urinary urgency (HP:0000012)2.57942700
47Abnormality of the renal medulla (HP:0100957)2.57873728
48Cerebellar dysplasia (HP:0007033)2.55708981
49Abnormality of the corticospinal tract (HP:0002492)2.53884430
50Spastic gait (HP:0002064)2.53142850
51Absence seizures (HP:0002121)2.52483709
52Gait imbalance (HP:0002141)2.51213980
53Hypomagnesemia (HP:0002917)2.49865757
54Retinal dysplasia (HP:0007973)2.48355246
55EEG with generalized epileptiform discharges (HP:0011198)2.48130575
56Abnormality of the labia minora (HP:0012880)2.47498453
57Absent speech (HP:0001344)2.47011235
58Insidious onset (HP:0003587)2.46039892
59Termporal pattern (HP:0011008)2.46039892
60Epileptiform EEG discharges (HP:0011182)2.45791282
61Pendular nystagmus (HP:0012043)2.45336061
62Protruding tongue (HP:0010808)2.44281557
63Neurofibrillary tangles (HP:0002185)2.43683229
64Hypsarrhythmia (HP:0002521)2.43130014
65Pheochromocytoma (HP:0002666)2.40444485
66Progressive macrocephaly (HP:0004481)2.38887526
67Acute encephalopathy (HP:0006846)2.37778199
68Cerebral inclusion bodies (HP:0100314)2.36994177
69Hypoplasia of the brainstem (HP:0002365)2.36915374
70Aplasia/Hypoplasia of the brainstem (HP:0007362)2.36915374
71Abnormality of the renal cortex (HP:0011035)2.36704123
72Lissencephaly (HP:0001339)2.36389405
733-Methylglutaconic aciduria (HP:0003535)2.34533334
74Atonic seizures (HP:0010819)2.34507738
75Inability to walk (HP:0002540)2.33647668
76Tetany (HP:0001281)2.32982942
77Apathy (HP:0000741)2.29151690
78Genetic anticipation (HP:0003743)2.28629775
79Urinary bladder sphincter dysfunction (HP:0002839)2.28619529
80Specific learning disability (HP:0001328)2.26804068
81Dialeptic seizures (HP:0011146)2.26733986
82Brushfield spots (HP:0001088)2.26616515
83Shoulder girdle muscle weakness (HP:0003547)2.24437698
84Renal cortical cysts (HP:0000803)2.23928100
85Lower limb muscle weakness (HP:0007340)2.23925664
86Diminished motivation (HP:0000745)2.22643089
87Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.21695610
88Gaze-evoked nystagmus (HP:0000640)2.20733547
89Hypoventilation (HP:0002791)2.18942288
90Hemiparesis (HP:0001269)2.18541036
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.17840845
92Abnormality of alanine metabolism (HP:0010916)2.17840845
93Hyperalaninemia (HP:0003348)2.17840845
94Polyuria (HP:0000103)2.17743873
95Abnormality of the pons (HP:0007361)2.17324385
96Abnormal mitochondria in muscle tissue (HP:0008316)2.15516653
97Dysdiadochokinesis (HP:0002075)2.15447671
98Action tremor (HP:0002345)2.14650872
99Hypoplasia of the pons (HP:0012110)2.14559453
100Neuroendocrine neoplasm (HP:0100634)2.14320734
101Patellar aplasia (HP:0006443)2.12785388
102Aplasia/Hypoplasia of the patella (HP:0006498)2.11578852
103Stereotypic behavior (HP:0000733)2.11478883
104Nephrogenic diabetes insipidus (HP:0009806)2.11262194
105Dysmetria (HP:0001310)2.11177401
106Pachygyria (HP:0001302)2.11106695
107Decreased activity of mitochondrial respiratory chain (HP:0008972)2.09590518
108Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.09590518
109Sclerocornea (HP:0000647)2.07443140
110Sacral dimple (HP:0000960)2.07186142
111Psychosis (HP:0000709)2.07105314
112Medial flaring of the eyebrow (HP:0010747)2.06949834
113Increased serum lactate (HP:0002151)2.04696992
114Diplopia (HP:0000651)2.04138921
115Abnormality of binocular vision (HP:0011514)2.04138921
116Sleep apnea (HP:0010535)2.03477799
117Chronic hepatic failure (HP:0100626)2.02557658
118Esotropia (HP:0000565)2.01549293
119Severe muscular hypotonia (HP:0006829)1.99729211
120Inappropriate behavior (HP:0000719)1.99667378
121Morphological abnormality of the pyramidal tract (HP:0002062)1.99549457
122Acute necrotizing encephalopathy (HP:0006965)1.99473220
123Generalized hypotonia (HP:0001290)1.99015815
124Restlessness (HP:0000711)1.97323654
125Poor suck (HP:0002033)1.96683907
126Aplasia/hypoplasia of the uterus (HP:0008684)1.95446819
127Bony spicule pigmentary retinopathy (HP:0007737)1.94921732
128Birth length less than 3rd percentile (HP:0003561)1.93736730
129Delusions (HP:0000746)1.93463275
130Exotropia (HP:0000577)1.93191544
131Degeneration of the lateral corticospinal tracts (HP:0002314)1.92521585
132Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.92521585
133Hypothermia (HP:0002045)1.90290826
134Cystic liver disease (HP:0006706)1.90130794
135Abnormal rod and cone electroretinograms (HP:0008323)1.90113296
136Abnormal EKG (HP:0003115)1.89263351
137Clonus (HP:0002169)1.89225866
138Impaired smooth pursuit (HP:0007772)1.88237794
139Sporadic (HP:0003745)1.87820888
140Focal dystonia (HP:0004373)1.86893605
141Torticollis (HP:0000473)1.86858698
142Abnormality of salivation (HP:0100755)1.86323274
143Congenital primary aphakia (HP:0007707)1.86142534
144Aplasia/Hypoplasia of the tibia (HP:0005772)1.86030394
145Gait ataxia (HP:0002066)1.85671623
146Neuronal loss in central nervous system (HP:0002529)1.85485374
147Humeroradial synostosis (HP:0003041)1.83398382
148Synostosis involving the elbow (HP:0003938)1.83398382
149Tubular atrophy (HP:0000092)1.81889618
150Thyroid-stimulating hormone excess (HP:0002925)1.81581257
151Decreased electroretinogram (ERG) amplitude (HP:0000654)1.81288198
152Methylmalonic acidemia (HP:0002912)1.81127801
153Hepatocellular necrosis (HP:0001404)1.80807548
154Abolished electroretinogram (ERG) (HP:0000550)1.80689461
155Lactic acidosis (HP:0003128)1.80078936
156Optic disc pallor (HP:0000543)1.79283027
157Abnormal biliary tract physiology (HP:0012439)1.78952074
158Bile duct proliferation (HP:0001408)1.78952074
159Increased corneal curvature (HP:0100692)1.77754170
160Keratoconus (HP:0000563)1.77754170
161Attenuation of retinal blood vessels (HP:0007843)1.77546715
162Progressive microcephaly (HP:0000253)1.77462971
163Short tibia (HP:0005736)1.75772685
164Duplicated collecting system (HP:0000081)1.75224627
165Abnormality of the renal collecting system (HP:0004742)1.74396401
166Decreased central vision (HP:0007663)1.72597784
167Aplasia/Hypoplasia of the tongue (HP:0010295)1.72322229
168Abnormality of magnesium homeostasis (HP:0004921)1.71850577
169Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.71082881
170Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.70602781
171Optic nerve hypoplasia (HP:0000609)1.69091242
172Genital tract atresia (HP:0001827)1.68706663
173Abnormal respiratory motile cilium morphology (HP:0005938)1.68082409
174Abnormal respiratory epithelium morphology (HP:0012253)1.68082409

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.19862955
2MAP3K94.07661472
3MAP4K23.79601718
4MINK13.12246554
5NTRK23.06059862
6UHMK12.95952182
7NTRK32.84535200
8ADRBK22.75533843
9EPHA32.67221770
10EPHA42.64437947
11FRK2.62434970
12MAP2K72.47770883
13ZAK2.44454568
14GRK12.41685319
15TAOK32.34239796
16SIK32.26438033
17MAP3K42.18398512
18SIK22.13156056
19TRIM282.10884304
20KSR12.01006172
21MAP3K121.99766727
22CDK191.95160040
23MAP2K41.86895396
24MAPK131.86006049
25TYRO31.66894404
26WNK41.61351183
27VRK11.57729209
28PHKG11.56344167
29PHKG21.56344167
30PAK61.54566437
31OXSR11.54374391
32DYRK21.52365869
33CDK51.51706768
34BCR1.50073793
35PINK11.47791752
36BCKDK1.44118141
37CLK11.42741575
38PIK3CA1.39043243
39DAPK21.33409070
40NTRK11.29800471
41CASK1.24272302
42CDK181.22873720
43PDK21.20657697
44FES1.19874430
45CDK141.18495643
46RIPK41.15213549
47PRPF4B1.14625174
48LATS21.11964807
49FGFR21.11372864
50CDK151.10149478
51DAPK11.08152739
52ERBB31.06604339
53MAP3K61.05650862
54CSNK1G11.04977953
55PRKCG1.04906205
56ARAF1.04571618
57MKNK21.04534952
58CSNK1A1L1.01979407
59CDK11A1.00923331
60PAK31.00250816
61GRK51.00243797
62RET1.00064115
63CDK80.97629113
64DYRK1A0.91892185
65INSRR0.91836504
66PNCK0.90280385
67CAMK2A0.90015000
68MAPKAPK50.89106760
69WNK30.85627335
70ACVR1B0.84627498
71PLK20.84255101
72IRAK20.81022304
73CAMKK10.80783911
74TNIK0.80374256
75RPS6KA50.80008689
76SRPK10.79967774
77AKT30.78354892
78GRK70.75912163
79NUAK10.75320634
80CSNK1G20.74319204
81KSR20.74204962
82PRKD30.73157564
83STK110.72995478
84MAPKAPK30.72101872
85PLK30.70355259
86STK390.68775466
87PRKCZ0.64098250
88ADRBK10.63652143
89ICK0.62770727
90RPS6KA20.60144463
91CAMK2B0.59807208
92IRAK10.59437024
93MAPK90.58750234
94PRKCI0.57031468
95MAPK40.55638852
96MARK20.55404251
97MAPK150.55083775
98MUSK0.54166544
99CSNK1G30.53352753
100KIT0.53163730
101CAMK10.51948561
102TESK20.50547359
103CSNK1A10.50497694
104PRKCE0.50151305
105HIPK20.49974202
106BUB10.49249245
107CAMK2D0.48674835
108TSSK60.47354857
109MAP2K60.46968604
110MAPK100.46199267
111FGR0.45269298
112TXK0.45088146
113IRAK40.44391164
114BRAF0.43952447
115PRKACA0.43925723
116NLK0.43535336
117TRIB30.43454172
118CSNK1D0.43043830
119TLK10.42671226
120BMPR1B0.42122667
121MARK30.41942831
122SGK2230.41758611
123SGK4940.41758611
124WEE10.41328003
125MKNK10.40821288
126LIMK10.40484903
127PTK2B0.39851124
128CHUK0.38382476
129TIE10.38076180
130CDK30.37962659
131PDGFRA0.37960983
132PKN10.36938378
133SGK20.35876205
134NME10.35700180
135FYN0.35206667
136CAMK40.35172811
137FER0.34885876
138PRKAA10.34871284
139EPHB20.33914834
140PRKCH0.33029463
141BRSK20.32758095
142IKBKB0.32496120
143STK40.32388198
144STK380.32149019
145CAMKK20.32001701
146CAMK2G0.31659987
147SCYL20.30513226
148ROCK20.30492982
149MAP3K10.29352961
150DYRK1B0.29299423
151TNK20.28413431
152STK160.27742858
153MAPK120.26825032

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.31416750
2Nicotine addiction_Homo sapiens_hsa050333.25987622
3Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.96150078
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.82948969
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.79955359
6GABAergic synapse_Homo sapiens_hsa047272.68263182
7Circadian entrainment_Homo sapiens_hsa047132.65814410
8Olfactory transduction_Homo sapiens_hsa047402.64402186
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50288891
10Dopaminergic synapse_Homo sapiens_hsa047282.42275317
11Morphine addiction_Homo sapiens_hsa050322.38971717
12Glutamatergic synapse_Homo sapiens_hsa047242.38348933
13Selenocompound metabolism_Homo sapiens_hsa004502.35103854
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.25604957
15Long-term potentiation_Homo sapiens_hsa047202.15828661
16Amphetamine addiction_Homo sapiens_hsa050312.09129384
17Cholinergic synapse_Homo sapiens_hsa047252.06326658
18Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.05795134
19Insulin secretion_Homo sapiens_hsa049111.98782022
20Protein export_Homo sapiens_hsa030601.96460284
21Cocaine addiction_Homo sapiens_hsa050301.92074419
22Cardiac muscle contraction_Homo sapiens_hsa042601.90132556
23Linoleic acid metabolism_Homo sapiens_hsa005911.90042207
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.89728953
25Oxidative phosphorylation_Homo sapiens_hsa001901.86336844
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.84530850
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.83933359
28Parkinsons disease_Homo sapiens_hsa050121.81986326
29Basal transcription factors_Homo sapiens_hsa030221.80469934
30Serotonergic synapse_Homo sapiens_hsa047261.79642641
31RNA polymerase_Homo sapiens_hsa030201.73176149
32Salivary secretion_Homo sapiens_hsa049701.70835753
33Long-term depression_Homo sapiens_hsa047301.67863828
34Gap junction_Homo sapiens_hsa045401.60520914
35Axon guidance_Homo sapiens_hsa043601.58198834
36Alzheimers disease_Homo sapiens_hsa050101.58162853
37Taste transduction_Homo sapiens_hsa047421.57288290
38Oxytocin signaling pathway_Homo sapiens_hsa049211.53402538
39Aldosterone synthesis and secretion_Homo sapiens_hsa049251.52432101
40Phototransduction_Homo sapiens_hsa047441.52326827
41Fanconi anemia pathway_Homo sapiens_hsa034601.51184390
42Renin secretion_Homo sapiens_hsa049241.49310856
43Gastric acid secretion_Homo sapiens_hsa049711.47383047
44Ether lipid metabolism_Homo sapiens_hsa005651.46406242
45Nitrogen metabolism_Homo sapiens_hsa009101.46381369
46Homologous recombination_Homo sapiens_hsa034401.46378226
47Collecting duct acid secretion_Homo sapiens_hsa049661.45009638
48Regulation of autophagy_Homo sapiens_hsa041401.40620148
49GnRH signaling pathway_Homo sapiens_hsa049121.39708067
50Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.37445568
51Calcium signaling pathway_Homo sapiens_hsa040201.27189058
52Vibrio cholerae infection_Homo sapiens_hsa051101.26887740
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.24778520
54One carbon pool by folate_Homo sapiens_hsa006701.21873474
55RNA degradation_Homo sapiens_hsa030181.19903633
56Tryptophan metabolism_Homo sapiens_hsa003801.18363512
57Huntingtons disease_Homo sapiens_hsa050161.18307230
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.15731436
59Caffeine metabolism_Homo sapiens_hsa002321.15485155
60ErbB signaling pathway_Homo sapiens_hsa040121.11818553
61Oocyte meiosis_Homo sapiens_hsa041141.11509765
62Melanogenesis_Homo sapiens_hsa049161.09910545
63Peroxisome_Homo sapiens_hsa041461.08564555
64Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.07717189
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.04116540
66Estrogen signaling pathway_Homo sapiens_hsa049151.02876334
67Vitamin B6 metabolism_Homo sapiens_hsa007500.99592898
68Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.96741039
69cAMP signaling pathway_Homo sapiens_hsa040240.96356481
70Glioma_Homo sapiens_hsa052140.96224311
71Alcoholism_Homo sapiens_hsa050340.94777151
72Propanoate metabolism_Homo sapiens_hsa006400.94534934
73Neurotrophin signaling pathway_Homo sapiens_hsa047220.88178259
74Sulfur relay system_Homo sapiens_hsa041220.87353479
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.87129989
76Type II diabetes mellitus_Homo sapiens_hsa049300.84254873
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83906175
78Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83220197
79cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79475575
80Dilated cardiomyopathy_Homo sapiens_hsa054140.77517684
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77450474
82Proteasome_Homo sapiens_hsa030500.75952417
83Mismatch repair_Homo sapiens_hsa034300.72126297
84Pyrimidine metabolism_Homo sapiens_hsa002400.71903303
85Endocytosis_Homo sapiens_hsa041440.69152708
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.68309621
87Purine metabolism_Homo sapiens_hsa002300.68098233
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.68002763
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.67419518
90VEGF signaling pathway_Homo sapiens_hsa043700.66657482
91Insulin signaling pathway_Homo sapiens_hsa049100.66391685
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.65832977
93Arachidonic acid metabolism_Homo sapiens_hsa005900.65412247
94Metabolic pathways_Homo sapiens_hsa011000.65134116
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65032525
96Choline metabolism in cancer_Homo sapiens_hsa052310.64421426
97MAPK signaling pathway_Homo sapiens_hsa040100.64263820
98Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.63807403
99Prion diseases_Homo sapiens_hsa050200.63413310
100Colorectal cancer_Homo sapiens_hsa052100.62805697
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62067586
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.62029098
103Glucagon signaling pathway_Homo sapiens_hsa049220.60239585
104Ribosome_Homo sapiens_hsa030100.59852681
105Dorso-ventral axis formation_Homo sapiens_hsa043200.58804125
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57847076
107Ras signaling pathway_Homo sapiens_hsa040140.57756239
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56686108
109Nucleotide excision repair_Homo sapiens_hsa034200.55770295
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55637883
111Wnt signaling pathway_Homo sapiens_hsa043100.55601677
112Renal cell carcinoma_Homo sapiens_hsa052110.55388608
113Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55313381
114N-Glycan biosynthesis_Homo sapiens_hsa005100.53444624
115Spliceosome_Homo sapiens_hsa030400.53075807
116Fatty acid elongation_Homo sapiens_hsa000620.52404672
117RNA transport_Homo sapiens_hsa030130.52244497
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51697936
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51611133
120Chemical carcinogenesis_Homo sapiens_hsa052040.50309410
121Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49912436
122Cysteine and methionine metabolism_Homo sapiens_hsa002700.49394675
123Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.48719868
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48178244
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.47453041
126Maturity onset diabetes of the young_Homo sapiens_hsa049500.47429950
127Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.46658438
128Circadian rhythm_Homo sapiens_hsa047100.46554861
129Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45256476
130Endometrial cancer_Homo sapiens_hsa052130.45039356
131Pancreatic secretion_Homo sapiens_hsa049720.45036500
132Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44321642
133Non-small cell lung cancer_Homo sapiens_hsa052230.43750722
134beta-Alanine metabolism_Homo sapiens_hsa004100.43556111
135Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43352182
136Thyroid hormone synthesis_Homo sapiens_hsa049180.39934200
137Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39891238
138Arginine and proline metabolism_Homo sapiens_hsa003300.39603615
139Carbohydrate digestion and absorption_Homo sapiens_hsa049730.39328098
140Rap1 signaling pathway_Homo sapiens_hsa040150.39217676
141Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39196387
142Primary bile acid biosynthesis_Homo sapiens_hsa001200.38868147
143Fat digestion and absorption_Homo sapiens_hsa049750.37461545
144Intestinal immune network for IgA production_Homo sapiens_hsa046720.37011179
145Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.36788995
146Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.36567018
147Butanoate metabolism_Homo sapiens_hsa006500.36390154
148Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.36196480
149Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34498524
150Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33611342
151Sulfur metabolism_Homo sapiens_hsa009200.33538581
152Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33338261
153Retinol metabolism_Homo sapiens_hsa008300.33040950
154Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.31863465
155Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.31695167
156Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.31428794
157AMPK signaling pathway_Homo sapiens_hsa041520.30547698
158Ovarian steroidogenesis_Homo sapiens_hsa049130.30530732
159Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29566190
160Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.27839915
161Base excision repair_Homo sapiens_hsa034100.27695538
162Folate biosynthesis_Homo sapiens_hsa007900.27165493
163Hedgehog signaling pathway_Homo sapiens_hsa043400.26866157

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