

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cell wall macromolecule metabolic process (GO:0044036) | 9.12796558 |
| 2 | proteasome assembly (GO:0043248) | 6.14304449 |
| 3 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 5.72858136 |
| 4 | negative regulation of T cell differentiation in thymus (GO:0033085) | 5.51598858 |
| 5 | regulation of immunoglobulin secretion (GO:0051023) | 5.50606744 |
| 6 | regulation of chronic inflammatory response (GO:0002676) | 5.30542378 |
| 7 | response to xenobiotic stimulus (GO:0009410) | 5.25507265 |
| 8 | cysteine metabolic process (GO:0006534) | 5.07091476 |
| 9 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 5.06876354 |
| 10 | opioid receptor signaling pathway (GO:0038003) | 4.79429114 |
| 11 | response to nitrosative stress (GO:0051409) | 4.51444215 |
| 12 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.24109777 |
| 13 | ether lipid metabolic process (GO:0046485) | 4.21045323 |
| 14 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.19551857 |
| 15 | piRNA metabolic process (GO:0034587) | 4.09185183 |
| 16 | regulation of acrosome reaction (GO:0060046) | 4.05395052 |
| 17 | sphingosine metabolic process (GO:0006670) | 4.00636176 |
| 18 | DNA deamination (GO:0045006) | 3.99285060 |
| 19 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.88935437 |
| 20 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.88783042 |
| 21 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.87025337 |
| 22 | Peyers patch development (GO:0048541) | 3.87025337 |
| 23 | positive regulation of chemokine secretion (GO:0090197) | 3.83349589 |
| 24 | diol metabolic process (GO:0034311) | 3.64476982 |
| 25 | rRNA methylation (GO:0031167) | 3.64046747 |
| 26 | rRNA modification (GO:0000154) | 3.57537826 |
| 27 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.56902698 |
| 28 | cell wall macromolecule catabolic process (GO:0016998) | 3.56132013 |
| 29 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.55503030 |
| 30 | behavioral response to ethanol (GO:0048149) | 3.53153133 |
| 31 | regulation of translational termination (GO:0006449) | 3.50985060 |
| 32 | adult feeding behavior (GO:0008343) | 3.48661916 |
| 33 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.47749213 |
| 34 | viral mRNA export from host cell nucleus (GO:0046784) | 3.46627042 |
| 35 | protein import into peroxisome matrix (GO:0016558) | 3.45643046 |
| 36 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.43961346 |
| 37 | thrombin receptor signaling pathway (GO:0070493) | 3.41219723 |
| 38 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.40483066 |
| 39 | regulation of gamma-delta T cell activation (GO:0046643) | 3.40246427 |
| 40 | glucosamine-containing compound catabolic process (GO:1901072) | 3.38507037 |
| 41 | fucose catabolic process (GO:0019317) | 3.38431740 |
| 42 | L-fucose metabolic process (GO:0042354) | 3.38431740 |
| 43 | L-fucose catabolic process (GO:0042355) | 3.38431740 |
| 44 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.36812467 |
| 45 | intracellular protein transmembrane import (GO:0044743) | 3.36547514 |
| 46 | regulation of chemokine secretion (GO:0090196) | 3.32168978 |
| 47 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.31938366 |
| 48 | L-ascorbic acid metabolic process (GO:0019852) | 3.30015810 |
| 49 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.25864007 |
| 50 | regulation of T cell differentiation in thymus (GO:0033081) | 3.25724735 |
| 51 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.25629167 |
| 52 | sphingoid metabolic process (GO:0046519) | 3.25520767 |
| 53 | positive regulation of interleukin-12 production (GO:0032735) | 3.24426612 |
| 54 | cellular response to interleukin-15 (GO:0071350) | 3.20243754 |
| 55 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.17795053 |
| 56 | regulation of immunoglobulin production (GO:0002637) | 3.17015086 |
| 57 | glutathione biosynthetic process (GO:0006750) | 3.14788546 |
| 58 | S-adenosylmethionine metabolic process (GO:0046500) | 3.12397069 |
| 59 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.10755035 |
| 60 | rhodopsin mediated signaling pathway (GO:0016056) | 3.06421582 |
| 61 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.02930874 |
| 62 | protein-cofactor linkage (GO:0018065) | 3.00830647 |
| 63 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.94332878 |
| 64 | termination of RNA polymerase III transcription (GO:0006386) | 2.94332878 |
| 65 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.92943549 |
| 66 | isotype switching (GO:0045190) | 2.92943549 |
| 67 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.92943549 |
| 68 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.90331805 |
| 69 | positive regulation of isotype switching (GO:0045830) | 2.89580364 |
| 70 | signal complex assembly (GO:0007172) | 2.89276618 |
| 71 | intra-S DNA damage checkpoint (GO:0031573) | 2.87962974 |
| 72 | nonribosomal peptide biosynthetic process (GO:0019184) | 2.86112990 |
| 73 | positive regulation of tolerance induction (GO:0002645) | 2.85010330 |
| 74 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.84233810 |
| 75 | positive regulation of immunoglobulin production (GO:0002639) | 2.80953706 |
| 76 | positive regulation of DNA recombination (GO:0045911) | 2.80553938 |
| 77 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.78752839 |
| 78 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.78693899 |
| 79 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.75090752 |
| 80 | auditory receptor cell stereocilium organization (GO:0060088) | 2.74608423 |
| 81 | interferon-gamma production (GO:0032609) | 2.70273907 |
| 82 | positive regulation of T cell apoptotic process (GO:0070234) | 2.67513069 |
| 83 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.67359341 |
| 84 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.67169731 |
| 85 | behavioral response to nicotine (GO:0035095) | 2.65391633 |
| 86 | negative T cell selection (GO:0043383) | 2.63028646 |
| 87 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.61335536 |
| 88 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.61335536 |
| 89 | NADH dehydrogenase complex assembly (GO:0010257) | 2.61335536 |
| 90 | regulation of mitochondrial depolarization (GO:0051900) | 2.58456173 |
| 91 | glycerol ether metabolic process (GO:0006662) | 2.56411962 |
| 92 | T cell lineage commitment (GO:0002360) | 2.55398430 |
| 93 | protein targeting to peroxisome (GO:0006625) | 2.55170162 |
| 94 | establishment of protein localization to peroxisome (GO:0072663) | 2.55170162 |
| 95 | protein localization to peroxisome (GO:0072662) | 2.55170162 |
| 96 | natural killer cell differentiation (GO:0001779) | 2.54970534 |
| 97 | platelet dense granule organization (GO:0060155) | 2.54664291 |
| 98 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.54018330 |
| 99 | regulation of podosome assembly (GO:0071801) | 2.52944354 |
| 100 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.52730161 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.61829700 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.21043130 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.97785354 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.70918610 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.56018312 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.48058340 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.47932258 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.37759083 |
| 9 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.34283304 |
| 10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.29845202 |
| 11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.14446397 |
| 12 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.06813367 |
| 13 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.06521710 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.00737329 |
| 15 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.96853639 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.93429852 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.91557748 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.87732207 |
| 19 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.85896583 |
| 20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.84807599 |
| 21 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.76146674 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.72954350 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.66649921 |
| 24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.66564351 |
| 25 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.65772523 |
| 26 | GATA3_26560356_Chip-Seq_TH2_Human | 1.60220043 |
| 27 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.58683053 |
| 28 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58094631 |
| 29 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.57839296 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.57733960 |
| 31 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.57631766 |
| 32 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.57306573 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55097403 |
| 34 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.50277773 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.49319173 |
| 36 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.47914933 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.47914933 |
| 38 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.46840347 |
| 39 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.46469073 |
| 40 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.43902732 |
| 41 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.42927019 |
| 42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.42927019 |
| 43 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.42570071 |
| 44 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40910917 |
| 45 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.40910917 |
| 46 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40833914 |
| 47 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.37697296 |
| 48 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.37697296 |
| 49 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.36894813 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.36418835 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.31883074 |
| 52 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29836333 |
| 53 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.29743074 |
| 54 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.29199073 |
| 55 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.26999719 |
| 56 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.24296592 |
| 57 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.24005713 |
| 58 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.23958085 |
| 59 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.22765535 |
| 60 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.22107598 |
| 61 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.21871807 |
| 62 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.20036219 |
| 63 | TCF4_23295773_ChIP-Seq_U87_Human | 1.19763344 |
| 64 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19692794 |
| 65 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.19578548 |
| 66 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.18510096 |
| 67 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18231921 |
| 68 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.17899201 |
| 69 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.17098476 |
| 70 | RXR_22108803_ChIP-Seq_LS180_Human | 1.16957156 |
| 71 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.16449025 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.15563422 |
| 73 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.15377744 |
| 74 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.14976786 |
| 75 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.14942477 |
| 76 | NCOR_22424771_ChIP-Seq_293T_Human | 1.14103801 |
| 77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.13914524 |
| 78 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13703776 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.12036781 |
| 80 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.11640269 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.11437460 |
| 82 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.09995753 |
| 83 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.09735420 |
| 84 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.09581532 |
| 85 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.08307760 |
| 86 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07965053 |
| 87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.07740228 |
| 88 | AR_20517297_ChIP-Seq_VCAP_Human | 1.07685008 |
| 89 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.07015317 |
| 90 | STAT3_23295773_ChIP-Seq_U87_Human | 1.06913920 |
| 91 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.06813299 |
| 92 | GATA1_22025678_ChIP-Seq_K562_Human | 1.06145553 |
| 93 | ERA_21632823_ChIP-Seq_H3396_Human | 1.05935706 |
| 94 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.99964512 |
| 95 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.99393212 |
| 96 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.97383403 |
| 97 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.96270596 |
| 98 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.95831346 |
| 99 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94213979 |
| 100 | NFYB_21822215_ChIP-Seq_K562_Human | 0.93871201 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000685_abnormal_immune_system | 3.95356091 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.44968583 |
| 3 | MP0005671_abnormal_response_to | 3.44450850 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.34063453 |
| 5 | MP0001968_abnormal_touch/_nociception | 3.20212088 |
| 6 | MP0001348_abnormal_lacrimal_gland | 2.96144964 |
| 7 | MP0008057_abnormal_DNA_replication | 2.94132694 |
| 8 | MP0003646_muscle_fatigue | 2.86089744 |
| 9 | MP0002876_abnormal_thyroid_physiology | 2.73945781 |
| 10 | MP0004147_increased_porphyrin_level | 2.73904630 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.58239870 |
| 12 | MP0009333_abnormal_splenocyte_physiolog | 2.52272209 |
| 13 | MP0009764_decreased_sensitivity_to | 2.25067436 |
| 14 | MP0002138_abnormal_hepatobiliary_system | 2.24585904 |
| 15 | MP0001790_abnormal_immune_system | 2.13591832 |
| 16 | MP0005387_immune_system_phenotype | 2.13591832 |
| 17 | MP0008872_abnormal_physiological_respon | 2.11902144 |
| 18 | MP0001501_abnormal_sleep_pattern | 2.09847222 |
| 19 | MP0003436_decreased_susceptibility_to | 1.95871975 |
| 20 | MP0001873_stomach_inflammation | 1.77594276 |
| 21 | MP0003195_calcinosis | 1.74422799 |
| 22 | MP0001800_abnormal_humoral_immune | 1.68100807 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.67966389 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.67350185 |
| 25 | MP0002736_abnormal_nociception_after | 1.61478240 |
| 26 | MP0005000_abnormal_immune_tolerance | 1.57100432 |
| 27 | MP0003890_abnormal_embryonic-extraembry | 1.55426225 |
| 28 | MP0001764_abnormal_homeostasis | 1.50633736 |
| 29 | MP0000750_abnormal_muscle_regeneration | 1.47867232 |
| 30 | MP0005646_abnormal_pituitary_gland | 1.47019009 |
| 31 | MP0003878_abnormal_ear_physiology | 1.41612463 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.41612463 |
| 33 | MP0006082_CNS_inflammation | 1.40169593 |
| 34 | MP0008877_abnormal_DNA_methylation | 1.36802337 |
| 35 | MP0009785_altered_susceptibility_to | 1.36007114 |
| 36 | MP0005360_urolithiasis | 1.33579284 |
| 37 | MP0005085_abnormal_gallbladder_physiolo | 1.32365749 |
| 38 | MP0005423_abnormal_somatic_nervous | 1.31770293 |
| 39 | MP0003763_abnormal_thymus_physiology | 1.29969594 |
| 40 | MP0001881_abnormal_mammary_gland | 1.27939128 |
| 41 | MP0009278_abnormal_bone_marrow | 1.22876527 |
| 42 | MP0004134_abnormal_chest_morphology | 1.22570920 |
| 43 | MP0002102_abnormal_ear_morphology | 1.22300864 |
| 44 | MP0001188_hyperpigmentation | 1.21672321 |
| 45 | MP0001986_abnormal_taste_sensitivity | 1.21214445 |
| 46 | MP0005310_abnormal_salivary_gland | 1.17615158 |
| 47 | MP0002723_abnormal_immune_serum | 1.17160880 |
| 48 | MP0009379_abnormal_foot_pigmentation | 1.17111280 |
| 49 | MP0003866_abnormal_defecation | 1.14085385 |
| 50 | MP0003724_increased_susceptibility_to | 1.10168283 |
| 51 | MP0000678_abnormal_parathyroid_gland | 1.09630766 |
| 52 | MP0002420_abnormal_adaptive_immunity | 1.09545090 |
| 53 | MP0010155_abnormal_intestine_physiology | 1.08889479 |
| 54 | MP0002006_tumorigenesis | 1.08852062 |
| 55 | MP0004142_abnormal_muscle_tone | 1.07919080 |
| 56 | MP0000569_abnormal_digit_pigmentation | 1.07520370 |
| 57 | MP0002148_abnormal_hypersensitivity_rea | 1.06980694 |
| 58 | MP0001819_abnormal_immune_cell | 1.05244676 |
| 59 | MP0003045_fibrosis | 1.04455616 |
| 60 | MP0003633_abnormal_nervous_system | 1.04316265 |
| 61 | MP0002272_abnormal_nervous_system | 1.01716732 |
| 62 | MP0002452_abnormal_antigen_presenting | 0.97811599 |
| 63 | MP0003959_abnormal_lean_body | 0.96891320 |
| 64 | MP0000716_abnormal_immune_system | 0.96317850 |
| 65 | MP0001533_abnormal_skeleton_physiology | 0.95807404 |
| 66 | MP0006035_abnormal_mitochondrial_morpho | 0.94466916 |
| 67 | MP0004742_abnormal_vestibular_system | 0.93777476 |
| 68 | MP0003567_abnormal_fetal_cardiomyocyte | 0.93278119 |
| 69 | MP0002398_abnormal_bone_marrow | 0.92151501 |
| 70 | MP0005167_abnormal_blood-brain_barrier | 0.91807088 |
| 71 | MP0001663_abnormal_digestive_system | 0.91635685 |
| 72 | MP0003329_amyloid_beta_deposits | 0.89599773 |
| 73 | MP0009745_abnormal_behavioral_response | 0.88298942 |
| 74 | MP0005025_abnormal_response_to | 0.85304762 |
| 75 | MP0002405_respiratory_system_inflammati | 0.84398149 |
| 76 | MP0002229_neurodegeneration | 0.82266628 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.82155279 |
| 78 | MP0000703_abnormal_thymus_morphology | 0.80918811 |
| 79 | MP0002163_abnormal_gland_morphology | 0.80690618 |
| 80 | MP0001970_abnormal_pain_threshold | 0.80247735 |
| 81 | MP0005075_abnormal_melanosome_morpholog | 0.79385669 |
| 82 | MP0002733_abnormal_thermal_nociception | 0.77487575 |
| 83 | MP0006036_abnormal_mitochondrial_physio | 0.76836655 |
| 84 | MP0008775_abnormal_heart_ventricle | 0.76773093 |
| 85 | MP0003191_abnormal_cellular_cholesterol | 0.74967074 |
| 86 | MP0006072_abnormal_retinal_apoptosis | 0.74925793 |
| 87 | MP0003638_abnormal_response/metabolism_ | 0.73682527 |
| 88 | MP0002234_abnormal_pharynx_morphology | 0.73088425 |
| 89 | MP0002429_abnormal_blood_cell | 0.71181709 |
| 90 | MP0001485_abnormal_pinna_reflex | 0.71090737 |
| 91 | MP0000689_abnormal_spleen_morphology | 0.70608425 |
| 92 | MP0003880_abnormal_central_pattern | 0.69557056 |
| 93 | MP0004782_abnormal_surfactant_physiolog | 0.67315326 |
| 94 | MP0005174_abnormal_tail_pigmentation | 0.67041754 |
| 95 | MP0000015_abnormal_ear_pigmentation | 0.66493636 |
| 96 | MP0004885_abnormal_endolymph | 0.66303245 |
| 97 | MP0003936_abnormal_reproductive_system | 0.66063452 |
| 98 | MP0005379_endocrine/exocrine_gland_phen | 0.65516553 |
| 99 | MP0000470_abnormal_stomach_morphology | 0.64920585 |
| 100 | MP0005253_abnormal_eye_physiology | 0.64861006 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 7.22337743 |
| 2 | Thyroid-stimulating hormone excess (HP:0002925) | 6.01484219 |
| 3 | Entropion (HP:0000621) | 5.25672409 |
| 4 | Increased IgM level (HP:0003496) | 5.08937542 |
| 5 | Attenuation of retinal blood vessels (HP:0007843) | 4.31258180 |
| 6 | Congenital, generalized hypertrichosis (HP:0004540) | 3.86349668 |
| 7 | IgG deficiency (HP:0004315) | 3.65498085 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.48795563 |
| 9 | Broad alveolar ridges (HP:0000187) | 3.46261774 |
| 10 | Type II lissencephaly (HP:0007260) | 3.39065965 |
| 11 | Intestinal atresia (HP:0011100) | 3.31177994 |
| 12 | Pancreatic cysts (HP:0001737) | 3.24865180 |
| 13 | Poikiloderma (HP:0001029) | 3.18837601 |
| 14 | Acute necrotizing encephalopathy (HP:0006965) | 3.12684221 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 3.10691147 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 3.10691147 |
| 17 | Cerebellar dysplasia (HP:0007033) | 2.98467889 |
| 18 | Pendular nystagmus (HP:0012043) | 2.94929388 |
| 19 | Cutaneous melanoma (HP:0012056) | 2.92267646 |
| 20 | Large for gestational age (HP:0001520) | 2.90837726 |
| 21 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.87633273 |
| 22 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.84082454 |
| 23 | Progressive macrocephaly (HP:0004481) | 2.75355117 |
| 24 | Acute encephalopathy (HP:0006846) | 2.71512767 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.69292347 |
| 26 | Chronic hepatic failure (HP:0100626) | 2.64191256 |
| 27 | Abnormality of DNA repair (HP:0003254) | 2.60381641 |
| 28 | Focal motor seizures (HP:0011153) | 2.59694804 |
| 29 | IgA deficiency (HP:0002720) | 2.58246913 |
| 30 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.54770053 |
| 31 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.51006854 |
| 32 | Increased CSF lactate (HP:0002490) | 2.50475026 |
| 33 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.50359403 |
| 34 | Mitochondrial inheritance (HP:0001427) | 2.41614901 |
| 35 | Submucous cleft hard palate (HP:0000176) | 2.41437482 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.40436646 |
| 37 | Optic disc pallor (HP:0000543) | 2.39840343 |
| 38 | Abnormality of macular pigmentation (HP:0008002) | 2.39081980 |
| 39 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.37669759 |
| 40 | Abnormality of the aortic arch (HP:0012303) | 2.36764095 |
| 41 | Stomach cancer (HP:0012126) | 2.33083327 |
| 42 | Chronic otitis media (HP:0000389) | 2.29232838 |
| 43 | Tubular atrophy (HP:0000092) | 2.23539884 |
| 44 | Decreased central vision (HP:0007663) | 2.21655687 |
| 45 | Hypoproteinemia (HP:0003075) | 2.21531280 |
| 46 | Amyotrophic lateral sclerosis (HP:0007354) | 2.21218313 |
| 47 | Microvesicular hepatic steatosis (HP:0001414) | 2.20854124 |
| 48 | Progressive inability to walk (HP:0002505) | 2.20546070 |
| 49 | Gaze-evoked nystagmus (HP:0000640) | 2.16745402 |
| 50 | Aplastic anemia (HP:0001915) | 2.15272037 |
| 51 | Mesangial abnormality (HP:0001966) | 2.14297861 |
| 52 | Fair hair (HP:0002286) | 2.13150179 |
| 53 | Agitation (HP:0000713) | 2.11112441 |
| 54 | Lipid accumulation in hepatocytes (HP:0006561) | 2.09394727 |
| 55 | Volvulus (HP:0002580) | 2.08390138 |
| 56 | Abnormality of T cells (HP:0002843) | 2.08175465 |
| 57 | Ectropion (HP:0000656) | 2.02846247 |
| 58 | Reticulocytopenia (HP:0001896) | 2.02440033 |
| 59 | Methylmalonic acidemia (HP:0002912) | 2.02415852 |
| 60 | Increased hepatocellular lipid droplets (HP:0006565) | 2.01943958 |
| 61 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.00552911 |
| 62 | Sensorimotor neuropathy (HP:0007141) | 2.00495959 |
| 63 | Inability to walk (HP:0002540) | 2.00259184 |
| 64 | Severe muscular hypotonia (HP:0006829) | 1.99613174 |
| 65 | Congenital sensorineural hearing impairment (HP:0008527) | 1.98050709 |
| 66 | Abnormality of T cell physiology (HP:0011840) | 1.97128597 |
| 67 | Thyroiditis (HP:0100646) | 1.97053720 |
| 68 | Retinal dysplasia (HP:0007973) | 1.96552962 |
| 69 | Abnormality of eosinophils (HP:0001879) | 1.95984518 |
| 70 | True hermaphroditism (HP:0010459) | 1.93139515 |
| 71 | Severe combined immunodeficiency (HP:0004430) | 1.92129139 |
| 72 | Cerebral edema (HP:0002181) | 1.88878025 |
| 73 | Absent speech (HP:0001344) | 1.86640639 |
| 74 | Pancreatic fibrosis (HP:0100732) | 1.86169502 |
| 75 | Oligodontia (HP:0000677) | 1.82907642 |
| 76 | Abnormality of T cell number (HP:0011839) | 1.82846454 |
| 77 | Broad-based gait (HP:0002136) | 1.81746025 |
| 78 | Tented upper lip vermilion (HP:0010804) | 1.79187435 |
| 79 | Keratitis (HP:0000491) | 1.77360648 |
| 80 | Increased corneal curvature (HP:0100692) | 1.76866823 |
| 81 | Keratoconus (HP:0000563) | 1.76866823 |
| 82 | T lymphocytopenia (HP:0005403) | 1.75569824 |
| 83 | Epiphyseal stippling (HP:0010655) | 1.75035913 |
| 84 | Increased serum lactate (HP:0002151) | 1.70765911 |
| 85 | Methylmalonic aciduria (HP:0012120) | 1.69959216 |
| 86 | Nephronophthisis (HP:0000090) | 1.68306941 |
| 87 | Chronic sinusitis (HP:0011109) | 1.67825688 |
| 88 | Lethargy (HP:0001254) | 1.67697078 |
| 89 | Myositis (HP:0100614) | 1.67257264 |
| 90 | Generalized tonic-clonic seizures (HP:0002069) | 1.66726136 |
| 91 | Amelogenesis imperfecta (HP:0000705) | 1.66467577 |
| 92 | Exertional dyspnea (HP:0002875) | 1.66215558 |
| 93 | Progressive microcephaly (HP:0000253) | 1.64835756 |
| 94 | Arthropathy (HP:0003040) | 1.63904270 |
| 95 | Hypoplasia of the pons (HP:0012110) | 1.63786362 |
| 96 | Long nose (HP:0003189) | 1.63714853 |
| 97 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.63559100 |
| 98 | Abnormality of the columella (HP:0009929) | 1.62253870 |
| 99 | Generalized hypopigmentation of hair (HP:0011358) | 1.59883579 |
| 100 | Thickened helices (HP:0000391) | 1.59552243 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 5.86934382 |
| 2 | TIE1 | 4.30486421 |
| 3 | TSSK6 | 3.93971820 |
| 4 | MAP3K12 | 3.69882569 |
| 5 | FRK | 3.12699247 |
| 6 | DYRK2 | 2.72700825 |
| 7 | GRK1 | 2.56274941 |
| 8 | MAP4K1 | 2.36621228 |
| 9 | ADRBK1 | 2.23886490 |
| 10 | TAOK3 | 2.08606594 |
| 11 | ZAK | 1.89317515 |
| 12 | TEC | 1.81736578 |
| 13 | PBK | 1.69703324 |
| 14 | NME1 | 1.65806721 |
| 15 | NUAK1 | 1.65614861 |
| 16 | MAPKAPK3 | 1.57447526 |
| 17 | TYRO3 | 1.53568776 |
| 18 | PIK3CG | 1.50712246 |
| 19 | IKBKB | 1.50318625 |
| 20 | PINK1 | 1.48358683 |
| 21 | BMPR1B | 1.47486262 |
| 22 | ITK | 1.46746752 |
| 23 | MST4 | 1.45191389 |
| 24 | TXK | 1.40679105 |
| 25 | CSNK1A1L | 1.33353067 |
| 26 | CAMKK2 | 1.30325653 |
| 27 | WNK4 | 1.28241065 |
| 28 | TRIM28 | 1.26770529 |
| 29 | TGFBR2 | 1.22754558 |
| 30 | EIF2AK1 | 1.18664971 |
| 31 | NEK1 | 1.18583934 |
| 32 | TLK1 | 1.16038001 |
| 33 | BCKDK | 1.09968607 |
| 34 | EIF2AK3 | 1.07258727 |
| 35 | CSNK1G2 | 1.06531747 |
| 36 | KIT | 1.06358025 |
| 37 | VRK2 | 0.99094008 |
| 38 | PRKCE | 0.96453061 |
| 39 | ACVR1B | 0.95667702 |
| 40 | CSNK1G3 | 0.94682336 |
| 41 | CHUK | 0.94637258 |
| 42 | BCR | 0.94335868 |
| 43 | GRK7 | 0.93785650 |
| 44 | HIPK2 | 0.93057130 |
| 45 | CSF1R | 0.91422327 |
| 46 | AKT3 | 0.91407345 |
| 47 | MKNK2 | 0.89808248 |
| 48 | TGFBR1 | 0.87960895 |
| 49 | OXSR1 | 0.83728377 |
| 50 | MKNK1 | 0.80292010 |
| 51 | MAPK13 | 0.80267415 |
| 52 | VRK1 | 0.79130303 |
| 53 | TAOK2 | 0.78556648 |
| 54 | PLK3 | 0.76947069 |
| 55 | SRPK1 | 0.75671413 |
| 56 | MAP3K5 | 0.75664187 |
| 57 | BTK | 0.75118857 |
| 58 | DAPK1 | 0.74713899 |
| 59 | DAPK2 | 0.73059712 |
| 60 | ALK | 0.68631260 |
| 61 | LIMK1 | 0.67801670 |
| 62 | PLK2 | 0.66870864 |
| 63 | PRKCG | 0.66641184 |
| 64 | CSNK1G1 | 0.66039457 |
| 65 | INSRR | 0.64925979 |
| 66 | IRAK1 | 0.62788371 |
| 67 | LCK | 0.61109190 |
| 68 | STK3 | 0.57838566 |
| 69 | GRK5 | 0.55042204 |
| 70 | KDR | 0.54508869 |
| 71 | FES | 0.53791831 |
| 72 | MYLK | 0.53325517 |
| 73 | PNCK | 0.52593626 |
| 74 | SYK | 0.51213615 |
| 75 | PRKCQ | 0.47815566 |
| 76 | BRSK2 | 0.46496301 |
| 77 | MAP3K11 | 0.43394490 |
| 78 | WEE1 | 0.42980264 |
| 79 | MAP3K4 | 0.42820215 |
| 80 | PDK2 | 0.42312151 |
| 81 | STK39 | 0.40265549 |
| 82 | CAMK2A | 0.39296701 |
| 83 | HCK | 0.38166880 |
| 84 | FER | 0.37752898 |
| 85 | CDK8 | 0.37497338 |
| 86 | CAMK4 | 0.37415411 |
| 87 | PIK3CA | 0.37356862 |
| 88 | NTRK3 | 0.37284095 |
| 89 | ATR | 0.37028965 |
| 90 | PAK6 | 0.36435506 |
| 91 | PAK3 | 0.36156038 |
| 92 | CAMK1 | 0.36076078 |
| 93 | PRKCI | 0.32504846 |
| 94 | STK38L | 0.32308655 |
| 95 | PRKCA | 0.32216210 |
| 96 | IGF1R | 0.31956252 |
| 97 | CAMK1G | 0.31715885 |
| 98 | PTK2B | 0.31548190 |
| 99 | MAP3K14 | 0.30364076 |
| 100 | CAMKK1 | 0.28284438 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.01513998 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.88676194 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.55145121 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.13378807 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.03343860 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.97422643 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 2.71804620 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.53362717 |
| 9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.48978363 |
| 10 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.42607398 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.32926667 |
| 12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.21675938 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 2.01194043 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.98725458 |
| 15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.95561903 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.95516518 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.72849805 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.67645330 |
| 19 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.66993883 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.64497111 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.55991456 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.53864036 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.46220393 |
| 24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.43628601 |
| 25 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.41347776 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.35941684 |
| 27 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.28853238 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.27322730 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.20213342 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.20003550 |
| 31 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.19321399 |
| 32 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.18365112 |
| 33 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.17822451 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.16059920 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15539558 |
| 36 | Sulfur relay system_Homo sapiens_hsa04122 | 1.12717114 |
| 37 | Alzheimers disease_Homo sapiens_hsa05010 | 1.11093276 |
| 38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.09814607 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.09315512 |
| 40 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.07214311 |
| 41 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.03632649 |
| 42 | Olfactory transduction_Homo sapiens_hsa04740 | 1.02546522 |
| 43 | Viral myocarditis_Homo sapiens_hsa05416 | 1.01080437 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.99137189 |
| 45 | Huntingtons disease_Homo sapiens_hsa05016 | 0.96870386 |
| 46 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.94565842 |
| 47 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.91557367 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.89639405 |
| 49 | Legionellosis_Homo sapiens_hsa05134 | 0.86955805 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.85370723 |
| 51 | ABC transporters_Homo sapiens_hsa02010 | 0.85019880 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.83664898 |
| 53 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.80139592 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.77348399 |
| 55 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76767992 |
| 56 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.74432864 |
| 57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.69025635 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.68772056 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59716383 |
| 60 | Spliceosome_Homo sapiens_hsa03040 | 0.59671295 |
| 61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59436433 |
| 62 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.59360318 |
| 63 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.57906728 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56371975 |
| 65 | Morphine addiction_Homo sapiens_hsa05032 | 0.52390283 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49730964 |
| 67 | Malaria_Homo sapiens_hsa05144 | 0.49214813 |
| 68 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.48776423 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.48738854 |
| 70 | DNA replication_Homo sapiens_hsa03030 | 0.47529397 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45282024 |
| 72 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.45214975 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45093576 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.45003342 |
| 75 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.44863684 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42319555 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.41618165 |
| 78 | Mismatch repair_Homo sapiens_hsa03430 | 0.41506723 |
| 79 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.40978149 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.39500491 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39486669 |
| 82 | Measles_Homo sapiens_hsa05162 | 0.38854190 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.38428639 |
| 84 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38108907 |
| 85 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37812694 |
| 86 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.37702352 |
| 87 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35878435 |
| 88 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.34046707 |
| 89 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.33328531 |
| 90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.32637296 |
| 91 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.30277852 |
| 92 | Homologous recombination_Homo sapiens_hsa03440 | 0.29858365 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29371984 |
| 94 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.26762722 |
| 95 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.25265545 |
| 96 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.23349429 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23188113 |
| 98 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.23066033 |
| 99 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22878576 |
| 100 | Circadian rhythm_Homo sapiens_hsa04710 | 0.21639560 |

