EIF1P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell wall macromolecule metabolic process (GO:0044036)9.12796558
2proteasome assembly (GO:0043248)6.14304449
3negative regulation of cytosolic calcium ion concentration (GO:0051481)5.72858136
4negative regulation of T cell differentiation in thymus (GO:0033085)5.51598858
5regulation of immunoglobulin secretion (GO:0051023)5.50606744
6regulation of chronic inflammatory response (GO:0002676)5.30542378
7response to xenobiotic stimulus (GO:0009410)5.25507265
8cysteine metabolic process (GO:0006534)5.07091476
9negative regulation of nitric oxide biosynthetic process (GO:0045019)5.06876354
10opioid receptor signaling pathway (GO:0038003)4.79429114
11response to nitrosative stress (GO:0051409)4.51444215
12CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)4.24109777
13ether lipid metabolic process (GO:0046485)4.21045323
14regulation of isotype switching to IgG isotypes (GO:0048302)4.19551857
15piRNA metabolic process (GO:0034587)4.09185183
16regulation of acrosome reaction (GO:0060046)4.05395052
17sphingosine metabolic process (GO:0006670)4.00636176
18DNA deamination (GO:0045006)3.99285060
19RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.88935437
20regulation of gamma-delta T cell differentiation (GO:0045586)3.88783042
21mucosal-associated lymphoid tissue development (GO:0048537)3.87025337
22Peyers patch development (GO:0048541)3.87025337
23positive regulation of chemokine secretion (GO:0090197)3.83349589
24diol metabolic process (GO:0034311)3.64476982
25rRNA methylation (GO:0031167)3.64046747
26rRNA modification (GO:0000154)3.57537826
27production of molecular mediator involved in inflammatory response (GO:0002532)3.56902698
28cell wall macromolecule catabolic process (GO:0016998)3.56132013
29nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.55503030
30behavioral response to ethanol (GO:0048149)3.53153133
31regulation of translational termination (GO:0006449)3.50985060
32adult feeding behavior (GO:0008343)3.48661916
33positive regulation of T cell differentiation in thymus (GO:0033089)3.47749213
34viral mRNA export from host cell nucleus (GO:0046784)3.46627042
35protein import into peroxisome matrix (GO:0016558)3.45643046
36negative regulation of cAMP-mediated signaling (GO:0043951)3.43961346
37thrombin receptor signaling pathway (GO:0070493)3.41219723
38positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.40483066
39regulation of gamma-delta T cell activation (GO:0046643)3.40246427
40glucosamine-containing compound catabolic process (GO:1901072)3.38507037
41fucose catabolic process (GO:0019317)3.38431740
42L-fucose metabolic process (GO:0042354)3.38431740
43L-fucose catabolic process (GO:0042355)3.38431740
44positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.36812467
45intracellular protein transmembrane import (GO:0044743)3.36547514
46regulation of chemokine secretion (GO:0090196)3.32168978
47regulation of rhodopsin mediated signaling pathway (GO:0022400)3.31938366
48L-ascorbic acid metabolic process (GO:0019852)3.30015810
49regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.25864007
50regulation of T cell differentiation in thymus (GO:0033081)3.25724735
51regulation of interleukin-12 biosynthetic process (GO:0045075)3.25629167
52sphingoid metabolic process (GO:0046519)3.25520767
53positive regulation of interleukin-12 production (GO:0032735)3.24426612
54cellular response to interleukin-15 (GO:0071350)3.20243754
55detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.17795053
56regulation of immunoglobulin production (GO:0002637)3.17015086
57glutathione biosynthetic process (GO:0006750)3.14788546
58S-adenosylmethionine metabolic process (GO:0046500)3.12397069
59negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.10755035
60rhodopsin mediated signaling pathway (GO:0016056)3.06421582
61establishment of protein localization to mitochondrial membrane (GO:0090151)3.02930874
62protein-cofactor linkage (GO:0018065)3.00830647
63transcription elongation from RNA polymerase III promoter (GO:0006385)2.94332878
64termination of RNA polymerase III transcription (GO:0006386)2.94332878
65somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.92943549
66isotype switching (GO:0045190)2.92943549
67somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.92943549
68exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.90331805
69positive regulation of isotype switching (GO:0045830)2.89580364
70signal complex assembly (GO:0007172)2.89276618
71intra-S DNA damage checkpoint (GO:0031573)2.87962974
72nonribosomal peptide biosynthetic process (GO:0019184)2.86112990
73positive regulation of tolerance induction (GO:0002645)2.85010330
74water-soluble vitamin biosynthetic process (GO:0042364)2.84233810
75positive regulation of immunoglobulin production (GO:0002639)2.80953706
76positive regulation of DNA recombination (GO:0045911)2.80553938
77positive regulation of chemokine biosynthetic process (GO:0045080)2.78752839
78adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.78693899
79positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.75090752
80auditory receptor cell stereocilium organization (GO:0060088)2.74608423
81interferon-gamma production (GO:0032609)2.70273907
82positive regulation of T cell apoptotic process (GO:0070234)2.67513069
83preassembly of GPI anchor in ER membrane (GO:0016254)2.67359341
84regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.67169731
85behavioral response to nicotine (GO:0035095)2.65391633
86negative T cell selection (GO:0043383)2.63028646
87mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.61335536
88mitochondrial respiratory chain complex I assembly (GO:0032981)2.61335536
89NADH dehydrogenase complex assembly (GO:0010257)2.61335536
90regulation of mitochondrial depolarization (GO:0051900)2.58456173
91glycerol ether metabolic process (GO:0006662)2.56411962
92T cell lineage commitment (GO:0002360)2.55398430
93protein targeting to peroxisome (GO:0006625)2.55170162
94establishment of protein localization to peroxisome (GO:0072663)2.55170162
95protein localization to peroxisome (GO:0072662)2.55170162
96natural killer cell differentiation (GO:0001779)2.54970534
97platelet dense granule organization (GO:0060155)2.54664291
98regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.54018330
99regulation of podosome assembly (GO:0071801)2.52944354
100negative regulation of synaptic transmission, GABAergic (GO:0032229)2.52730161

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.61829700
2VDR_22108803_ChIP-Seq_LS180_Human3.21043130
3GABP_17652178_ChIP-ChIP_JURKAT_Human2.97785354
4EST1_17652178_ChIP-ChIP_JURKAT_Human2.70918610
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.56018312
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.48058340
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.47932258
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.37759083
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.34283304
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29845202
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.14446397
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.06813367
13PCGF2_27294783_Chip-Seq_ESCs_Mouse2.06521710
14VDR_23849224_ChIP-Seq_CD4+_Human2.00737329
15RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.96853639
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.93429852
17ETS1_20019798_ChIP-Seq_JURKAT_Human1.91557748
18EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.87732207
19BCAT_22108803_ChIP-Seq_LS180_Human1.85896583
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.84807599
21EGR1_23403033_ChIP-Seq_LIVER_Mouse1.76146674
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.72954350
23EWS_26573619_Chip-Seq_HEK293_Human1.66649921
24PCGF2_27294783_Chip-Seq_NPCs_Mouse1.66564351
25TP53_22573176_ChIP-Seq_HFKS_Human1.65772523
26GATA3_26560356_Chip-Seq_TH2_Human1.60220043
27STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.58683053
28POU3F2_20337985_ChIP-ChIP_501MEL_Human1.58094631
29EGR1_19032775_ChIP-ChIP_M12_Human1.57839296
30P300_19829295_ChIP-Seq_ESCs_Human1.57733960
31GATA3_21878914_ChIP-Seq_MCF-7_Human1.57631766
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.57306573
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.55097403
34PRDM14_20953172_ChIP-Seq_ESCs_Human1.50277773
35IRF8_22096565_ChIP-ChIP_GC-B_Human1.49319173
36FOXA1_27270436_Chip-Seq_PROSTATE_Human1.47914933
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.47914933
38CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.46840347
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46469073
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43902732
41IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42927019
42CBP_20019798_ChIP-Seq_JUKART_Human1.42927019
43PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.42570071
44TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40910917
45POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.40910917
46LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40833914
47NANOG_19829295_ChIP-Seq_ESCs_Human1.37697296
48SOX2_19829295_ChIP-Seq_ESCs_Human1.37697296
49GBX2_23144817_ChIP-Seq_PC3_Human1.36894813
50FUS_26573619_Chip-Seq_HEK293_Human1.36418835
51NANOG_20526341_ChIP-Seq_ESCs_Human1.31883074
52MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.29836333
53FOXA1_21572438_ChIP-Seq_LNCaP_Human1.29743074
54MYC_18940864_ChIP-ChIP_HL60_Human1.29199073
55TCF4_22108803_ChIP-Seq_LS180_Human1.26999719
56ER_23166858_ChIP-Seq_MCF-7_Human1.24296592
57CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.24005713
58ELK1_19687146_ChIP-ChIP_HELA_Human1.23958085
59FOXP3_21729870_ChIP-Seq_TREG_Human1.22765535
60TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.22107598
61PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.21871807
62RUNX_20019798_ChIP-Seq_JUKART_Human1.20036219
63TCF4_23295773_ChIP-Seq_U87_Human1.19763344
64SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19692794
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.19578548
66IGF1R_20145208_ChIP-Seq_DFB_Human1.18510096
67TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.18231921
68HOXB7_26014856_ChIP-Seq_BT474_Human1.17899201
69IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.17098476
70RXR_22108803_ChIP-Seq_LS180_Human1.16957156
71SMRT_27268052_Chip-Seq_Bcells_Human1.16449025
72ERG_20517297_ChIP-Seq_VCAP_Human1.15563422
73KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15377744
74TDRD3_21172665_ChIP-Seq_MCF-7_Human1.14976786
75ELK1_22589737_ChIP-Seq_MCF10A_Human1.14942477
76NCOR_22424771_ChIP-Seq_293T_Human1.14103801
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.13914524
78GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.13703776
79FOXH1_21741376_ChIP-Seq_EPCs_Human1.12036781
80MYC_18555785_ChIP-Seq_MESCs_Mouse1.11640269
81EZH2_27294783_Chip-Seq_NPCs_Mouse1.11437460
82EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.09995753
83FOXH1_21741376_ChIP-Seq_ESCs_Human1.09735420
84DCP1A_22483619_ChIP-Seq_HELA_Human1.09581532
85CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08307760
86FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07965053
87IRF1_19129219_ChIP-ChIP_H3396_Human1.07740228
88AR_20517297_ChIP-Seq_VCAP_Human1.07685008
89TAF2_19829295_ChIP-Seq_ESCs_Human1.07015317
90STAT3_23295773_ChIP-Seq_U87_Human1.06913920
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.06813299
92GATA1_22025678_ChIP-Seq_K562_Human1.06145553
93ERA_21632823_ChIP-Seq_H3396_Human1.05935706
94ETV1_20927104_ChIP-Seq_GIST48_Human0.99964512
95P53_21459846_ChIP-Seq_SAOS-2_Human0.99393212
96TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97383403
97TTF2_22483619_ChIP-Seq_HELA_Human0.96270596
98CRX_20693478_ChIP-Seq_RETINA_Mouse0.95831346
99RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94213979
100NFYB_21822215_ChIP-Seq_K562_Human0.93871201

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000685_abnormal_immune_system3.95356091
2MP0003806_abnormal_nucleotide_metabolis3.44968583
3MP0005671_abnormal_response_to3.44450850
4MP0001835_abnormal_antigen_presentation3.34063453
5MP0001968_abnormal_touch/_nociception3.20212088
6MP0001348_abnormal_lacrimal_gland2.96144964
7MP0008057_abnormal_DNA_replication2.94132694
8MP0003646_muscle_fatigue2.86089744
9MP0002876_abnormal_thyroid_physiology2.73945781
10MP0004147_increased_porphyrin_level2.73904630
11MP0008875_abnormal_xenobiotic_pharmacok2.58239870
12MP0009333_abnormal_splenocyte_physiolog2.52272209
13MP0009764_decreased_sensitivity_to2.25067436
14MP0002138_abnormal_hepatobiliary_system2.24585904
15MP0001790_abnormal_immune_system2.13591832
16MP0005387_immune_system_phenotype2.13591832
17MP0008872_abnormal_physiological_respon2.11902144
18MP0001501_abnormal_sleep_pattern2.09847222
19MP0003436_decreased_susceptibility_to1.95871975
20MP0001873_stomach_inflammation1.77594276
21MP0003195_calcinosis1.74422799
22MP0001800_abnormal_humoral_immune1.68100807
23MP0005551_abnormal_eye_electrophysiolog1.67966389
24MP0005645_abnormal_hypothalamus_physiol1.67350185
25MP0002736_abnormal_nociception_after1.61478240
26MP0005000_abnormal_immune_tolerance1.57100432
27MP0003890_abnormal_embryonic-extraembry1.55426225
28MP0001764_abnormal_homeostasis1.50633736
29MP0000750_abnormal_muscle_regeneration1.47867232
30MP0005646_abnormal_pituitary_gland1.47019009
31MP0003878_abnormal_ear_physiology1.41612463
32MP0005377_hearing/vestibular/ear_phenot1.41612463
33MP0006082_CNS_inflammation1.40169593
34MP0008877_abnormal_DNA_methylation1.36802337
35MP0009785_altered_susceptibility_to1.36007114
36MP0005360_urolithiasis1.33579284
37MP0005085_abnormal_gallbladder_physiolo1.32365749
38MP0005423_abnormal_somatic_nervous1.31770293
39MP0003763_abnormal_thymus_physiology1.29969594
40MP0001881_abnormal_mammary_gland1.27939128
41MP0009278_abnormal_bone_marrow1.22876527
42MP0004134_abnormal_chest_morphology1.22570920
43MP0002102_abnormal_ear_morphology1.22300864
44MP0001188_hyperpigmentation1.21672321
45MP0001986_abnormal_taste_sensitivity1.21214445
46MP0005310_abnormal_salivary_gland1.17615158
47MP0002723_abnormal_immune_serum1.17160880
48MP0009379_abnormal_foot_pigmentation1.17111280
49MP0003866_abnormal_defecation1.14085385
50MP0003724_increased_susceptibility_to1.10168283
51MP0000678_abnormal_parathyroid_gland1.09630766
52MP0002420_abnormal_adaptive_immunity1.09545090
53MP0010155_abnormal_intestine_physiology1.08889479
54MP0002006_tumorigenesis1.08852062
55MP0004142_abnormal_muscle_tone1.07919080
56MP0000569_abnormal_digit_pigmentation1.07520370
57MP0002148_abnormal_hypersensitivity_rea1.06980694
58MP0001819_abnormal_immune_cell1.05244676
59MP0003045_fibrosis1.04455616
60MP0003633_abnormal_nervous_system1.04316265
61MP0002272_abnormal_nervous_system1.01716732
62MP0002452_abnormal_antigen_presenting0.97811599
63MP0003959_abnormal_lean_body0.96891320
64MP0000716_abnormal_immune_system0.96317850
65MP0001533_abnormal_skeleton_physiology0.95807404
66MP0006035_abnormal_mitochondrial_morpho0.94466916
67MP0004742_abnormal_vestibular_system0.93777476
68MP0003567_abnormal_fetal_cardiomyocyte0.93278119
69MP0002398_abnormal_bone_marrow0.92151501
70MP0005167_abnormal_blood-brain_barrier0.91807088
71MP0001663_abnormal_digestive_system0.91635685
72MP0003329_amyloid_beta_deposits0.89599773
73MP0009745_abnormal_behavioral_response0.88298942
74MP0005025_abnormal_response_to0.85304762
75MP0002405_respiratory_system_inflammati0.84398149
76MP0002229_neurodegeneration0.82266628
77MP0002693_abnormal_pancreas_physiology0.82155279
78MP0000703_abnormal_thymus_morphology0.80918811
79MP0002163_abnormal_gland_morphology0.80690618
80MP0001970_abnormal_pain_threshold0.80247735
81MP0005075_abnormal_melanosome_morpholog0.79385669
82MP0002733_abnormal_thermal_nociception0.77487575
83MP0006036_abnormal_mitochondrial_physio0.76836655
84MP0008775_abnormal_heart_ventricle0.76773093
85MP0003191_abnormal_cellular_cholesterol0.74967074
86MP0006072_abnormal_retinal_apoptosis0.74925793
87MP0003638_abnormal_response/metabolism_0.73682527
88MP0002234_abnormal_pharynx_morphology0.73088425
89MP0002429_abnormal_blood_cell0.71181709
90MP0001485_abnormal_pinna_reflex0.71090737
91MP0000689_abnormal_spleen_morphology0.70608425
92MP0003880_abnormal_central_pattern0.69557056
93MP0004782_abnormal_surfactant_physiolog0.67315326
94MP0005174_abnormal_tail_pigmentation0.67041754
95MP0000015_abnormal_ear_pigmentation0.66493636
96MP0004885_abnormal_endolymph0.66303245
97MP0003936_abnormal_reproductive_system0.66063452
98MP0005379_endocrine/exocrine_gland_phen0.65516553
99MP0000470_abnormal_stomach_morphology0.64920585
100MP0005253_abnormal_eye_physiology0.64861006

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)7.22337743
2Thyroid-stimulating hormone excess (HP:0002925)6.01484219
3Entropion (HP:0000621)5.25672409
4Increased IgM level (HP:0003496)5.08937542
5Attenuation of retinal blood vessels (HP:0007843)4.31258180
6Congenital, generalized hypertrichosis (HP:0004540)3.86349668
7IgG deficiency (HP:0004315)3.65498085
83-Methylglutaconic aciduria (HP:0003535)3.48795563
9Broad alveolar ridges (HP:0000187)3.46261774
10Type II lissencephaly (HP:0007260)3.39065965
11Intestinal atresia (HP:0011100)3.31177994
12Pancreatic cysts (HP:0001737)3.24865180
13Poikiloderma (HP:0001029)3.18837601
14Acute necrotizing encephalopathy (HP:0006965)3.12684221
15Molar tooth sign on MRI (HP:0002419)3.10691147
16Abnormality of midbrain morphology (HP:0002418)3.10691147
17Cerebellar dysplasia (HP:0007033)2.98467889
18Pendular nystagmus (HP:0012043)2.94929388
19Cutaneous melanoma (HP:0012056)2.92267646
20Large for gestational age (HP:0001520)2.90837726
21Absent rod-and cone-mediated responses on ERG (HP:0007688)2.87633273
22Abnormal rod and cone electroretinograms (HP:0008323)2.84082454
23Progressive macrocephaly (HP:0004481)2.75355117
24Acute encephalopathy (HP:0006846)2.71512767
25Congenital stationary night blindness (HP:0007642)2.69292347
26Chronic hepatic failure (HP:0100626)2.64191256
27Abnormality of DNA repair (HP:0003254)2.60381641
28Focal motor seizures (HP:0011153)2.59694804
29IgA deficiency (HP:0002720)2.58246913
30Elevated erythrocyte sedimentation rate (HP:0003565)2.54770053
31Abnormal mitochondria in muscle tissue (HP:0008316)2.51006854
32Increased CSF lactate (HP:0002490)2.50475026
33Decreased electroretinogram (ERG) amplitude (HP:0000654)2.50359403
34Mitochondrial inheritance (HP:0001427)2.41614901
35Submucous cleft hard palate (HP:0000176)2.41437482
36Abolished electroretinogram (ERG) (HP:0000550)2.40436646
37Optic disc pallor (HP:0000543)2.39840343
38Abnormality of macular pigmentation (HP:0008002)2.39081980
39Pancreatic islet-cell hyperplasia (HP:0004510)2.37669759
40Abnormality of the aortic arch (HP:0012303)2.36764095
41Stomach cancer (HP:0012126)2.33083327
42Chronic otitis media (HP:0000389)2.29232838
43Tubular atrophy (HP:0000092)2.23539884
44Decreased central vision (HP:0007663)2.21655687
45Hypoproteinemia (HP:0003075)2.21531280
46Amyotrophic lateral sclerosis (HP:0007354)2.21218313
47Microvesicular hepatic steatosis (HP:0001414)2.20854124
48Progressive inability to walk (HP:0002505)2.20546070
49Gaze-evoked nystagmus (HP:0000640)2.16745402
50Aplastic anemia (HP:0001915)2.15272037
51Mesangial abnormality (HP:0001966)2.14297861
52Fair hair (HP:0002286)2.13150179
53Agitation (HP:0000713)2.11112441
54Lipid accumulation in hepatocytes (HP:0006561)2.09394727
55Volvulus (HP:0002580)2.08390138
56Abnormality of T cells (HP:0002843)2.08175465
57Ectropion (HP:0000656)2.02846247
58Reticulocytopenia (HP:0001896)2.02440033
59Methylmalonic acidemia (HP:0002912)2.02415852
60Increased hepatocellular lipid droplets (HP:0006565)2.01943958
61Bony spicule pigmentary retinopathy (HP:0007737)2.00552911
62Sensorimotor neuropathy (HP:0007141)2.00495959
63Inability to walk (HP:0002540)2.00259184
64Severe muscular hypotonia (HP:0006829)1.99613174
65Congenital sensorineural hearing impairment (HP:0008527)1.98050709
66Abnormality of T cell physiology (HP:0011840)1.97128597
67Thyroiditis (HP:0100646)1.97053720
68Retinal dysplasia (HP:0007973)1.96552962
69Abnormality of eosinophils (HP:0001879)1.95984518
70True hermaphroditism (HP:0010459)1.93139515
71Severe combined immunodeficiency (HP:0004430)1.92129139
72Cerebral edema (HP:0002181)1.88878025
73Absent speech (HP:0001344)1.86640639
74Pancreatic fibrosis (HP:0100732)1.86169502
75Oligodontia (HP:0000677)1.82907642
76Abnormality of T cell number (HP:0011839)1.82846454
77Broad-based gait (HP:0002136)1.81746025
78Tented upper lip vermilion (HP:0010804)1.79187435
79Keratitis (HP:0000491)1.77360648
80Increased corneal curvature (HP:0100692)1.76866823
81Keratoconus (HP:0000563)1.76866823
82T lymphocytopenia (HP:0005403)1.75569824
83Epiphyseal stippling (HP:0010655)1.75035913
84Increased serum lactate (HP:0002151)1.70765911
85Methylmalonic aciduria (HP:0012120)1.69959216
86Nephronophthisis (HP:0000090)1.68306941
87Chronic sinusitis (HP:0011109)1.67825688
88Lethargy (HP:0001254)1.67697078
89Myositis (HP:0100614)1.67257264
90Generalized tonic-clonic seizures (HP:0002069)1.66726136
91Amelogenesis imperfecta (HP:0000705)1.66467577
92Exertional dyspnea (HP:0002875)1.66215558
93Progressive microcephaly (HP:0000253)1.64835756
94Arthropathy (HP:0003040)1.63904270
95Hypoplasia of the pons (HP:0012110)1.63786362
96Long nose (HP:0003189)1.63714853
97Abnormality of transition element cation homeostasis (HP:0011030)1.63559100
98Abnormality of the columella (HP:0009929)1.62253870
99Generalized hypopigmentation of hair (HP:0011358)1.59883579
100Thickened helices (HP:0000391)1.59552243

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ADRBK25.86934382
2TIE14.30486421
3TSSK63.93971820
4MAP3K123.69882569
5FRK3.12699247
6DYRK22.72700825
7GRK12.56274941
8MAP4K12.36621228
9ADRBK12.23886490
10TAOK32.08606594
11ZAK1.89317515
12TEC1.81736578
13PBK1.69703324
14NME11.65806721
15NUAK11.65614861
16MAPKAPK31.57447526
17TYRO31.53568776
18PIK3CG1.50712246
19IKBKB1.50318625
20PINK11.48358683
21BMPR1B1.47486262
22ITK1.46746752
23MST41.45191389
24TXK1.40679105
25CSNK1A1L1.33353067
26CAMKK21.30325653
27WNK41.28241065
28TRIM281.26770529
29TGFBR21.22754558
30EIF2AK11.18664971
31NEK11.18583934
32TLK11.16038001
33BCKDK1.09968607
34EIF2AK31.07258727
35CSNK1G21.06531747
36KIT1.06358025
37VRK20.99094008
38PRKCE0.96453061
39ACVR1B0.95667702
40CSNK1G30.94682336
41CHUK0.94637258
42BCR0.94335868
43GRK70.93785650
44HIPK20.93057130
45CSF1R0.91422327
46AKT30.91407345
47MKNK20.89808248
48TGFBR10.87960895
49OXSR10.83728377
50MKNK10.80292010
51MAPK130.80267415
52VRK10.79130303
53TAOK20.78556648
54PLK30.76947069
55SRPK10.75671413
56MAP3K50.75664187
57BTK0.75118857
58DAPK10.74713899
59DAPK20.73059712
60ALK0.68631260
61LIMK10.67801670
62PLK20.66870864
63PRKCG0.66641184
64CSNK1G10.66039457
65INSRR0.64925979
66IRAK10.62788371
67LCK0.61109190
68STK30.57838566
69GRK50.55042204
70KDR0.54508869
71FES0.53791831
72MYLK0.53325517
73PNCK0.52593626
74SYK0.51213615
75PRKCQ0.47815566
76BRSK20.46496301
77MAP3K110.43394490
78WEE10.42980264
79MAP3K40.42820215
80PDK20.42312151
81STK390.40265549
82CAMK2A0.39296701
83HCK0.38166880
84FER0.37752898
85CDK80.37497338
86CAMK40.37415411
87PIK3CA0.37356862
88NTRK30.37284095
89ATR0.37028965
90PAK60.36435506
91PAK30.36156038
92CAMK10.36076078
93PRKCI0.32504846
94STK38L0.32308655
95PRKCA0.32216210
96IGF1R0.31956252
97CAMK1G0.31715885
98PTK2B0.31548190
99MAP3K140.30364076
100CAMKK10.28284438

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.01513998
2Allograft rejection_Homo sapiens_hsa053303.88676194
3Autoimmune thyroid disease_Homo sapiens_hsa053203.55145121
4Primary immunodeficiency_Homo sapiens_hsa053403.13378807
5Intestinal immune network for IgA production_Homo sapiens_hsa046723.03343860
6Phototransduction_Homo sapiens_hsa047442.97422643
7Proteasome_Homo sapiens_hsa030502.71804620
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.53362717
9Nitrogen metabolism_Homo sapiens_hsa009102.48978363
10Caffeine metabolism_Homo sapiens_hsa002322.42607398
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.32926667
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.21675938
13RNA polymerase_Homo sapiens_hsa030202.01194043
14Type I diabetes mellitus_Homo sapiens_hsa049401.98725458
15Oxidative phosphorylation_Homo sapiens_hsa001901.95561903
16Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.95516518
17Graft-versus-host disease_Homo sapiens_hsa053321.72849805
18Linoleic acid metabolism_Homo sapiens_hsa005911.67645330
19Cyanoamino acid metabolism_Homo sapiens_hsa004601.66993883
20RNA degradation_Homo sapiens_hsa030181.64497111
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55991456
22Protein export_Homo sapiens_hsa030601.53864036
23Ribosome_Homo sapiens_hsa030101.46220393
24Antigen processing and presentation_Homo sapiens_hsa046121.43628601
25alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.41347776
26Parkinsons disease_Homo sapiens_hsa050121.35941684
27T cell receptor signaling pathway_Homo sapiens_hsa046601.28853238
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.27322730
29Peroxisome_Homo sapiens_hsa041461.20213342
30Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.20003550
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.19321399
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.18365112
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.17822451
34One carbon pool by folate_Homo sapiens_hsa006701.16059920
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15539558
36Sulfur relay system_Homo sapiens_hsa041221.12717114
37Alzheimers disease_Homo sapiens_hsa050101.11093276
38Vitamin B6 metabolism_Homo sapiens_hsa007501.09814607
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.09315512
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.07214311
41Hematopoietic cell lineage_Homo sapiens_hsa046401.03632649
42Olfactory transduction_Homo sapiens_hsa047401.02546522
43Viral myocarditis_Homo sapiens_hsa054161.01080437
44Purine metabolism_Homo sapiens_hsa002300.99137189
45Huntingtons disease_Homo sapiens_hsa050160.96870386
46NOD-like receptor signaling pathway_Homo sapiens_hsa046210.94565842
47Nucleotide excision repair_Homo sapiens_hsa034200.91557367
48RNA transport_Homo sapiens_hsa030130.89639405
49Legionellosis_Homo sapiens_hsa051340.86955805
50Cardiac muscle contraction_Homo sapiens_hsa042600.85370723
51ABC transporters_Homo sapiens_hsa020100.85019880
52Pyrimidine metabolism_Homo sapiens_hsa002400.83664898
53Rheumatoid arthritis_Homo sapiens_hsa053230.80139592
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77348399
55Glutathione metabolism_Homo sapiens_hsa004800.76767992
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74432864
57Basal transcription factors_Homo sapiens_hsa030220.69025635
58Arachidonic acid metabolism_Homo sapiens_hsa005900.68772056
59Primary bile acid biosynthesis_Homo sapiens_hsa001200.59716383
60Spliceosome_Homo sapiens_hsa030400.59671295
61Ether lipid metabolism_Homo sapiens_hsa005650.59436433
62Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59360318
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57906728
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56371975
65Morphine addiction_Homo sapiens_hsa050320.52390283
66beta-Alanine metabolism_Homo sapiens_hsa004100.49730964
67Malaria_Homo sapiens_hsa051440.49214813
68Systemic lupus erythematosus_Homo sapiens_hsa053220.48776423
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48738854
70DNA replication_Homo sapiens_hsa030300.47529397
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.45282024
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.45214975
73Chemical carcinogenesis_Homo sapiens_hsa052040.45093576
74Mineral absorption_Homo sapiens_hsa049780.45003342
75Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44863684
76Metabolic pathways_Homo sapiens_hsa011000.42319555
77Taste transduction_Homo sapiens_hsa047420.41618165
78Mismatch repair_Homo sapiens_hsa034300.41506723
79Dorso-ventral axis formation_Homo sapiens_hsa043200.40978149
80Retinol metabolism_Homo sapiens_hsa008300.39500491
81Regulation of autophagy_Homo sapiens_hsa041400.39486669
82Measles_Homo sapiens_hsa051620.38854190
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38428639
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38108907
85Epstein-Barr virus infection_Homo sapiens_hsa051690.37812694
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37702352
87Nicotine addiction_Homo sapiens_hsa050330.35878435
88Butanoate metabolism_Homo sapiens_hsa006500.34046707
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.33328531
90Sulfur metabolism_Homo sapiens_hsa009200.32637296
91Propanoate metabolism_Homo sapiens_hsa006400.30277852
92Homologous recombination_Homo sapiens_hsa034400.29858365
93Ovarian steroidogenesis_Homo sapiens_hsa049130.29371984
94Glycerolipid metabolism_Homo sapiens_hsa005610.26762722
95Fanconi anemia pathway_Homo sapiens_hsa034600.25265545
96Tryptophan metabolism_Homo sapiens_hsa003800.23349429
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23188113
98Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.23066033
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.22878576
100Circadian rhythm_Homo sapiens_hsa047100.21639560

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »