Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.56435266 |
2 | positive regulation by symbiont of host defense response (GO:0052509) | 5.26133105 |
3 | modulation by symbiont of host defense response (GO:0052031) | 5.26133105 |
4 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.26133105 |
5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.26133105 |
6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.26133105 |
7 | modulation by symbiont of host immune response (GO:0052553) | 5.26133105 |
8 | positive regulation of interferon-alpha production (GO:0032727) | 5.19203625 |
9 | regulation of interferon-alpha production (GO:0032647) | 4.89185153 |
10 | response to type I interferon (GO:0034340) | 4.81553135 |
11 | cellular response to type I interferon (GO:0071357) | 4.76131783 |
12 | type I interferon signaling pathway (GO:0060337) | 4.76131783 |
13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.23687923 |
14 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.23687923 |
15 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.07851659 |
16 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.07131642 |
17 | * response to interferon-alpha (GO:0035455) | 4.04069187 |
18 | neutrophil activation involved in immune response (GO:0002283) | 3.97120572 |
19 | * regulation of viral genome replication (GO:0045069) | 3.94305308 |
20 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.90901793 |
21 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.89817231 |
22 | positive regulation of interferon-beta production (GO:0032728) | 3.89314461 |
23 | response to peptidoglycan (GO:0032494) | 3.89231221 |
24 | cellular response to interferon-beta (GO:0035458) | 3.81708172 |
25 | cellular response to exogenous dsRNA (GO:0071360) | 3.76699774 |
26 | * negative regulation of viral genome replication (GO:0045071) | 3.73587221 |
27 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.72009071 |
28 | cellular response to ethanol (GO:0071361) | 3.66317112 |
29 | * negative regulation of viral process (GO:0048525) | 3.65859903 |
30 | cellular response to interferon-alpha (GO:0035457) | 3.62363159 |
31 | superoxide anion generation (GO:0042554) | 3.60888041 |
32 | response to interferon-beta (GO:0035456) | 3.51982853 |
33 | macrophage activation involved in immune response (GO:0002281) | 3.49329282 |
34 | positive regulation of antigen processing and presentation (GO:0002579) | 3.47571656 |
35 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.43188574 |
36 | nuclear pore complex assembly (GO:0051292) | 3.39774692 |
37 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.37916207 |
38 | regulation of RIG-I signaling pathway (GO:0039535) | 3.36376317 |
39 | response to exogenous dsRNA (GO:0043330) | 3.35599437 |
40 | detection of other organism (GO:0098543) | 3.33771495 |
41 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.32894921 |
42 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.31988428 |
43 | mitotic sister chromatid cohesion (GO:0007064) | 3.31428906 |
44 | detection of molecule of bacterial origin (GO:0032490) | 3.31030887 |
45 | immunoglobulin mediated immune response (GO:0016064) | 3.29713311 |
46 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.28941510 |
47 | I-kappaB phosphorylation (GO:0007252) | 3.28759288 |
48 | neutrophil activation (GO:0042119) | 3.28012558 |
49 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.27158010 |
50 | * response to host immune response (GO:0052572) | 3.25160242 |
51 | * response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.25160242 |
52 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 3.24888929 |
53 | natural killer cell mediated cytotoxicity (GO:0042267) | 3.19080291 |
54 | natural killer cell mediated immunity (GO:0002228) | 3.19080291 |
55 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.17938483 |
56 | T-helper 1 type immune response (GO:0042088) | 3.17924490 |
57 | granulocyte activation (GO:0036230) | 3.17176250 |
58 | microglial cell activation (GO:0001774) | 3.16192317 |
59 | cellular response to virus (GO:0098586) | 3.14985720 |
60 | negative regulation of interleukin-12 production (GO:0032695) | 3.13627781 |
61 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.12858229 |
62 | regulation of antigen processing and presentation (GO:0002577) | 3.08975412 |
63 | positive regulation of interleukin-12 production (GO:0032735) | 3.08138558 |
64 | negative regulation of T cell mediated immunity (GO:0002710) | 3.07982193 |
65 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.04654360 |
66 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.04654360 |
67 | regulation of protein polyubiquitination (GO:1902914) | 3.00567984 |
68 | positive regulation of defense response to virus by host (GO:0002230) | 3.00342201 |
69 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.00326024 |
70 | response to dsRNA (GO:0043331) | 2.96280321 |
71 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.94870981 |
72 | negative regulation of B cell proliferation (GO:0030889) | 2.94849158 |
73 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.92556468 |
74 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.90233432 |
75 | * defense response to virus (GO:0051607) | 2.90187629 |
76 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.89350931 |
77 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.87674174 |
78 | * response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.85353335 |
79 | * response to host (GO:0075136) | 2.85353335 |
80 | * response to host defenses (GO:0052200) | 2.85353335 |
81 | detection of bacterium (GO:0016045) | 2.85294991 |
82 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.84777167 |
83 | detection of external biotic stimulus (GO:0098581) | 2.84678747 |
84 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.84319080 |
85 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.84232119 |
86 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.83042400 |
87 | nuclear pore organization (GO:0006999) | 2.82641605 |
88 | positive regulation of response to biotic stimulus (GO:0002833) | 2.82604357 |
89 | regulation of interferon-beta production (GO:0032648) | 2.82418409 |
90 | T cell migration (GO:0072678) | 2.82388368 |
91 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.81306069 |
92 | regulation of natural killer cell differentiation (GO:0032823) | 2.80754566 |
93 | response to muramyl dipeptide (GO:0032495) | 2.78975720 |
94 | regulation of response to interferon-gamma (GO:0060330) | 2.78940798 |
95 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.77948745 |
96 | positive regulation of type 2 immune response (GO:0002830) | 2.74984636 |
97 | response to interleukin-15 (GO:0070672) | 2.74520627 |
98 | myeloid cell activation involved in immune response (GO:0002275) | 2.73871294 |
99 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.73491004 |
100 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.71766020 |
101 | regulation of activation of Janus kinase activity (GO:0010533) | 2.71001432 |
102 | negative regulation of cell killing (GO:0031342) | 2.70975349 |
103 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.70975349 |
104 | response to interferon-gamma (GO:0034341) | 2.70131599 |
105 | cellular response to interferon-gamma (GO:0071346) | 2.68422132 |
106 | protein K11-linked deubiquitination (GO:0035871) | 2.67922236 |
107 | necroptotic process (GO:0070266) | 2.67819735 |
108 | dendritic cell chemotaxis (GO:0002407) | 2.67093933 |
109 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.66804569 |
110 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.66708032 |
111 | myeloid dendritic cell activation (GO:0001773) | 2.65760289 |
112 | B cell proliferation (GO:0042100) | 2.65541728 |
113 | hepatocyte apoptotic process (GO:0097284) | 2.65456870 |
114 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.65453112 |
115 | positive regulation of heat generation (GO:0031652) | 2.64110713 |
116 | cytokine secretion (GO:0050663) | 2.63474701 |
117 | macrophage activation (GO:0042116) | 2.63398670 |
118 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.63191812 |
119 | regulation of defense response to virus by host (GO:0050691) | 2.62638812 |
120 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.61076985 |
121 | negative regulation of type I interferon production (GO:0032480) | 2.60606630 |
122 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.59729850 |
123 | interferon-gamma production (GO:0032609) | 2.59381704 |
124 | pore complex assembly (GO:0046931) | 2.59306645 |
125 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.58935176 |
126 | respiratory burst (GO:0045730) | 2.58922262 |
127 | positive regulation of protein import into nucleus, translocation (GO:0033160) | 2.58558811 |
128 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.58281883 |
129 | pre-miRNA processing (GO:0031054) | 2.58145905 |
130 | positive regulation of T cell migration (GO:2000406) | 2.58052133 |
131 | dendritic cell migration (GO:0036336) | 2.58003918 |
132 | detection of biotic stimulus (GO:0009595) | 2.57721490 |
133 | B cell receptor signaling pathway (GO:0050853) | 2.57128513 |
134 | regulation of gamma-delta T cell activation (GO:0046643) | 2.56530590 |
135 | regulation of necroptotic process (GO:0060544) | 2.56214916 |
136 | myeloid dendritic cell differentiation (GO:0043011) | 2.54168241 |
137 | cellular extravasation (GO:0045123) | 2.53908669 |
138 | defense response to protozoan (GO:0042832) | 2.53218610 |
139 | germinal center formation (GO:0002467) | 2.52922553 |
140 | regulation of interleukin-1 secretion (GO:0050704) | 2.52352950 |
141 | * response to virus (GO:0009615) | 2.52164970 |
142 | cellular response to interleukin-15 (GO:0071350) | 2.51554157 |
143 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.50689263 |
144 | B cell mediated immunity (GO:0019724) | 2.50328782 |
145 | JAK-STAT cascade (GO:0007259) | 2.49041455 |
146 | natural killer cell activation involved in immune response (GO:0002323) | 2.48771841 |
147 | negative regulation of viral entry into host cell (GO:0046597) | 2.48280349 |
148 | negative regulation of DNA repair (GO:0045738) | 2.48165002 |
149 | regulation of establishment of cell polarity (GO:2000114) | 2.46914957 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.78575168 |
2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 5.53496908 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.28308096 |
4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.91589585 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.26147248 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.16254338 |
7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.47901516 |
8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.03812076 |
9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.03123770 |
10 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.87628398 |
11 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.75622090 |
12 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.66507419 |
13 | GATA1_22025678_ChIP-Seq_K562_Human | 2.34232537 |
14 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.30627854 |
15 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.25851258 |
16 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.24093910 |
17 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.09935188 |
18 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.09858057 |
19 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.08907996 |
20 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.02631449 |
21 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.95828516 |
22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.90856755 |
23 | TP53_16413492_ChIP-PET_HCT116_Human | 1.68947234 |
24 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.67389116 |
25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.65135510 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.64220953 |
27 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.64071537 |
28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.60168093 |
29 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.58193000 |
30 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.54791865 |
31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53694165 |
32 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.52842686 |
33 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.52255821 |
34 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.51558093 |
35 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.51098202 |
36 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.50109365 |
37 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.47869727 |
38 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.47721900 |
39 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.46937434 |
40 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46755688 |
41 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.44398092 |
42 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.43221101 |
43 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.39205886 |
44 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.37437811 |
45 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36640714 |
46 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.36568047 |
47 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.36493764 |
48 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.36121926 |
49 | MYB_26560356_Chip-Seq_TH2_Human | 1.35387467 |
50 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.30176777 |
51 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.28233151 |
52 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26034014 |
53 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.25239123 |
54 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22965677 |
55 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.21532754 |
56 | MYB_26560356_Chip-Seq_TH1_Human | 1.21361897 |
57 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.21000544 |
58 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20824158 |
59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.20756764 |
60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.20323253 |
61 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.19707357 |
62 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.19209582 |
63 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.17618260 |
64 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.15689787 |
65 | CJUN_26792858_Chip-Seq_BT549_Human | 1.15484313 |
66 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.15466637 |
67 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.13404836 |
68 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.13372085 |
69 | FUS_26573619_Chip-Seq_HEK293_Human | 1.12720219 |
70 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11939943 |
71 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.11906701 |
72 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.11422708 |
73 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.11089971 |
74 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.10733006 |
75 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.10604311 |
76 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.10557410 |
77 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.10432581 |
78 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.09976755 |
79 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.08523136 |
80 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.08523136 |
81 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.07510669 |
82 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.07305488 |
83 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.07189541 |
84 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.07078222 |
85 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.07018335 |
86 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.06275569 |
87 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.06275569 |
88 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.05720877 |
89 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.05623500 |
90 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.05219359 |
91 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.04485517 |
92 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.02582164 |
93 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01953626 |
94 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.01788502 |
95 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.01473867 |
96 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.01415352 |
97 | P300_19829295_ChIP-Seq_ESCs_Human | 1.00717874 |
98 | SPI1_23127762_ChIP-Seq_K562_Human | 1.00111911 |
99 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.00002933 |
100 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.99929118 |
101 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.99805839 |
102 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.99568008 |
103 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98303580 |
104 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.97766878 |
105 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97519147 |
106 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.97445357 |
107 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.96329451 |
108 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.96221097 |
109 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.96145015 |
110 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.95644567 |
111 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.95611958 |
112 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.95536715 |
113 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.95499334 |
114 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.95189954 |
115 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.94398250 |
116 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.94102553 |
117 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.94098119 |
118 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.93722801 |
119 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.92416433 |
120 | GATA3_26560356_Chip-Seq_TH2_Human | 0.92235446 |
121 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.91293178 |
122 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.90490156 |
123 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.90403952 |
124 | * CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.89576397 |
125 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.89403658 |
126 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.88237045 |
127 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.88114227 |
128 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.87880235 |
129 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.86169896 |
130 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.85698605 |
131 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85590445 |
132 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.85284689 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.41792374 |
2 | MP0008057_abnormal_DNA_replication | 4.00402816 |
3 | MP0009785_altered_susceptibility_to | 3.54341310 |
4 | MP0003724_increased_susceptibility_to | 3.13413239 |
5 | MP0003436_decreased_susceptibility_to | 2.80376588 |
6 | MP0005387_immune_system_phenotype | 2.75368532 |
7 | MP0001790_abnormal_immune_system | 2.75368532 |
8 | * MP0002148_abnormal_hypersensitivity_rea | 2.72963646 |
9 | MP0008438_abnormal_cutaneous_collagen | 2.58544966 |
10 | MP0005000_abnormal_immune_tolerance | 2.53696287 |
11 | MP0000569_abnormal_digit_pigmentation | 2.52753919 |
12 | MP0002419_abnormal_innate_immunity | 2.52744873 |
13 | * MP0005025_abnormal_response_to | 2.51621323 |
14 | MP0000685_abnormal_immune_system | 2.44641460 |
15 | MP0005671_abnormal_response_to | 2.40499272 |
16 | MP0002452_abnormal_antigen_presenting | 2.33610148 |
17 | MP0001800_abnormal_humoral_immune | 2.31699255 |
18 | MP0002009_preneoplasia | 2.25453254 |
19 | MP0006054_spinal_hemorrhage | 2.15720269 |
20 | * MP0002723_abnormal_immune_serum | 2.14842223 |
21 | MP0006082_CNS_inflammation | 2.10070730 |
22 | MP0002166_altered_tumor_susceptibility | 2.05659504 |
23 | MP0002006_tumorigenesis | 2.00644450 |
24 | MP0009764_decreased_sensitivity_to | 1.94547623 |
25 | * MP0001819_abnormal_immune_cell | 1.91023139 |
26 | * MP0002420_abnormal_adaptive_immunity | 1.86678443 |
27 | MP0002877_abnormal_melanocyte_morpholog | 1.78510373 |
28 | MP0010155_abnormal_intestine_physiology | 1.73589447 |
29 | MP0001533_abnormal_skeleton_physiology | 1.72175188 |
30 | MP0005464_abnormal_platelet_physiology | 1.69009962 |
31 | MP0003300_gastrointestinal_ulcer | 1.65442265 |
32 | MP0004510_myositis | 1.63218281 |
33 | MP0005076_abnormal_cell_differentiation | 1.58456355 |
34 | MP0004808_abnormal_hematopoietic_stem | 1.56688361 |
35 | MP0001845_abnormal_inflammatory_respons | 1.54306592 |
36 | MP0004947_skin_inflammation | 1.53880147 |
37 | MP0002405_respiratory_system_inflammati | 1.47324714 |
38 | MP0002277_abnormal_respiratory_mucosa | 1.46650767 |
39 | MP0003448_altered_tumor_morphology | 1.46063356 |
40 | MP0001853_heart_inflammation | 1.45409735 |
41 | MP0003303_peritoneal_inflammation | 1.43224180 |
42 | * MP0000716_abnormal_immune_system | 1.40035053 |
43 | MP0002998_abnormal_bone_remodeling | 1.39734520 |
44 | * MP0002398_abnormal_bone_marrow | 1.37166693 |
45 | MP0008469_abnormal_protein_level | 1.35994265 |
46 | MP0010678_abnormal_skin_adnexa | 1.35719298 |
47 | MP0010307_abnormal_tumor_latency | 1.35242664 |
48 | MP0009278_abnormal_bone_marrow | 1.34721871 |
49 | MP0005503_abnormal_tendon_morphology | 1.34512333 |
50 | MP0005174_abnormal_tail_pigmentation | 1.33075757 |
51 | MP0004782_abnormal_surfactant_physiolog | 1.32846144 |
52 | MP0005397_hematopoietic_system_phenotyp | 1.29519616 |
53 | MP0001545_abnormal_hematopoietic_system | 1.29519616 |
54 | MP0002396_abnormal_hematopoietic_system | 1.29025060 |
55 | MP0005275_abnormal_skin_tensile | 1.28188016 |
56 | MP0000015_abnormal_ear_pigmentation | 1.26490457 |
57 | MP0005058_abnormal_lysosome_morphology | 1.26312917 |
58 | MP0003656_abnormal_erythrocyte_physiolo | 1.24924958 |
59 | MP0000858_altered_metastatic_potential | 1.23523552 |
60 | MP0005257_abnormal_intraocular_pressure | 1.21686173 |
61 | MP0010094_abnormal_chromosome_stability | 1.21645502 |
62 | MP0003566_abnormal_cell_adhesion | 1.21376846 |
63 | MP0003045_fibrosis | 1.20989544 |
64 | MP0003221_abnormal_cardiomyocyte_apopto | 1.20431119 |
65 | MP0000343_altered_response_to | 1.18709518 |
66 | MP0004883_abnormal_blood_vessel | 1.17041194 |
67 | MP0003091_abnormal_cell_migration | 1.15650672 |
68 | MP0003941_abnormal_skin_development | 1.13859841 |
69 | MP0002138_abnormal_hepatobiliary_system | 1.13201053 |
70 | MP0005390_skeleton_phenotype | 1.11984962 |
71 | MP0003943_abnormal_hepatobiliary_system | 1.11930302 |
72 | * MP0002429_abnormal_blood_cell | 1.11714524 |
73 | MP0005621_abnormal_cell_physiology | 1.10465778 |
74 | MP0001873_stomach_inflammation | 1.07169894 |
75 | MP0005171_absent_coat_pigmentation | 1.06739247 |
76 | MP0005310_abnormal_salivary_gland | 1.06672122 |
77 | MP0003763_abnormal_thymus_physiology | 1.06585636 |
78 | MP0003828_pulmonary_edema | 1.06164733 |
79 | MP0000689_abnormal_spleen_morphology | 1.05025652 |
80 | MP0003172_abnormal_lysosome_physiology | 1.04050616 |
81 | MP0000703_abnormal_thymus_morphology | 1.03830214 |
82 | MP0000490_abnormal_crypts_of | 1.03631228 |
83 | MP0002933_joint_inflammation | 1.03607020 |
84 | MP0002332_abnormal_exercise_endurance | 1.03113426 |
85 | MP0003191_abnormal_cellular_cholesterol | 1.02998807 |
86 | MP0000427_abnormal_hair_cycle | 1.01470907 |
87 | MP0003705_abnormal_hypodermis_morpholog | 1.00830634 |
88 | MP0000371_diluted_coat_color | 1.00372939 |
89 | MP0002722_abnormal_immune_system | 0.99823323 |
90 | MP0001958_emphysema | 0.99249062 |
91 | MP0000767_abnormal_smooth_muscle | 0.98000521 |
92 | MP0003890_abnormal_embryonic-extraembry | 0.97122555 |
93 | MP0009697_abnormal_copulation | 0.94924456 |
94 | MP0003252_abnormal_bile_duct | 0.94276156 |
95 | MP0001879_abnormal_lymphatic_vessel | 0.94044280 |
96 | MP0009333_abnormal_splenocyte_physiolog | 0.93973961 |
97 | MP0000383_abnormal_hair_follicle | 0.93939548 |
98 | MP0008877_abnormal_DNA_methylation | 0.93805388 |
99 | * MP0009763_increased_sensitivity_to | 0.93445167 |
100 | MP0003279_aneurysm | 0.93354895 |
101 | MP0002060_abnormal_skin_morphology | 0.92024712 |
102 | MP0001915_intracranial_hemorrhage | 0.87293526 |
103 | MP0002254_reproductive_system_inflammat | 0.86808630 |
104 | MP0003787_abnormal_imprinting | 0.86500638 |
105 | MP0005023_abnormal_wound_healing | 0.84320961 |
106 | MP0008007_abnormal_cellular_replicative | 0.81264438 |
107 | MP0003183_abnormal_peptide_metabolism | 0.78784911 |
108 | MP0003950_abnormal_plasma_membrane | 0.78584127 |
109 | MP0005623_abnormal_meninges_morphology | 0.77909533 |
110 | MP0002019_abnormal_tumor_incidence | 0.77872167 |
111 | MP0001348_abnormal_lacrimal_gland | 0.77119861 |
112 | MP0001188_hyperpigmentation | 0.75434901 |
113 | MP0009115_abnormal_fat_cell | 0.75242753 |
114 | MP0005384_cellular_phenotype | 0.74607020 |
115 | MP0001346_abnormal_lacrimal_gland | 0.74509336 |
116 | MP0002928_abnormal_bile_duct | 0.73461486 |
117 | MP0003453_abnormal_keratinocyte_physiol | 0.73043728 |
118 | MP0010352_gastrointestinal_tract_polyps | 0.71109749 |
119 | MP0001881_abnormal_mammary_gland | 0.70756181 |
120 | MP0005164_abnormal_response_to | 0.69807766 |
121 | MP0003795_abnormal_bone_structure | 0.69550401 |
122 | MP0010234_abnormal_vibrissa_follicle | 0.69535618 |
123 | MP0003868_abnormal_feces_composition | 0.69107413 |
124 | MP0000350_abnormal_cell_proliferation | 0.68379242 |
125 | MP0001851_eye_inflammation | 0.67934137 |
126 | MP0000627_abnormal_mammary_gland | 0.67848183 |
127 | MP0002132_abnormal_respiratory_system | 0.67732306 |
128 | MP0000372_irregular_coat_pigmentation | 0.66916046 |
129 | MP0000249_abnormal_blood_vessel | 0.66836694 |
130 | MP0002168_other_aberrant_phenotype | 0.66482249 |
131 | MP0005367_renal/urinary_system_phenotyp | 0.66341236 |
132 | MP0000516_abnormal_urinary_system | 0.66341236 |
133 | MP0003866_abnormal_defecation | 0.63119585 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 4.72686025 |
2 | Recurrent abscess formation (HP:0002722) | 4.67049285 |
3 | Recurrent bacterial skin infections (HP:0005406) | 4.38305734 |
4 | Prostate neoplasm (HP:0100787) | 4.36199602 |
5 | Myositis (HP:0100614) | 3.83669765 |
6 | Retrobulbar optic neuritis (HP:0100654) | 3.79183306 |
7 | Optic neuritis (HP:0100653) | 3.79183306 |
8 | Orchitis (HP:0100796) | 3.76997868 |
9 | Autoimmune thrombocytopenia (HP:0001973) | 3.58467229 |
10 | T lymphocytopenia (HP:0005403) | 3.52788294 |
11 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.52113551 |
12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.33047415 |
13 | Recurrent fungal infections (HP:0002841) | 3.26838647 |
14 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.24001126 |
15 | Mediastinal lymphadenopathy (HP:0100721) | 3.21864417 |
16 | Chronic otitis media (HP:0000389) | 3.20051895 |
17 | Vasculitis (HP:0002633) | 3.16200364 |
18 | Chromsome breakage (HP:0040012) | 3.09242121 |
19 | Gingivitis (HP:0000230) | 3.05473474 |
20 | Abnormality of macrophages (HP:0004311) | 3.04295817 |
21 | Recurrent viral infections (HP:0004429) | 3.01541894 |
22 | Periodontitis (HP:0000704) | 2.96821809 |
23 | Recurrent skin infections (HP:0001581) | 2.95209938 |
24 | Papillary thyroid carcinoma (HP:0002895) | 2.92737361 |
25 | Basal ganglia calcification (HP:0002135) | 2.90921959 |
26 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.82681584 |
27 | Recurrent cutaneous fungal infections (HP:0011370) | 2.82681584 |
28 | Volvulus (HP:0002580) | 2.82145628 |
29 | Gingival bleeding (HP:0000225) | 2.75979344 |
30 | Subacute progressive viral hepatitis (HP:0006572) | 2.72765456 |
31 | Abnormality of the prostate (HP:0008775) | 2.68380674 |
32 | Recurrent pneumonia (HP:0006532) | 2.63161957 |
33 | Arterial thrombosis (HP:0004420) | 2.61880078 |
34 | Pulmonary infiltrates (HP:0002113) | 2.50647386 |
35 | Obstructive lung disease (HP:0006536) | 2.49786743 |
36 | Chronic obstructive pulmonary disease (HP:0006510) | 2.49786743 |
37 | Viral hepatitis (HP:0006562) | 2.49679767 |
38 | Osteolytic defects of the hand bones (HP:0009699) | 2.47730862 |
39 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.47730862 |
40 | Thick nail (HP:0001805) | 2.45797318 |
41 | Tetraparesis (HP:0002273) | 2.44521117 |
42 | Chronic diarrhea (HP:0002028) | 2.42964524 |
43 | Abnormality of chromosome stability (HP:0003220) | 2.42749694 |
44 | Recurrent lower respiratory tract infections (HP:0002783) | 2.42441739 |
45 | Genetic anticipation (HP:0003743) | 2.41815242 |
46 | Deep philtrum (HP:0002002) | 2.41682202 |
47 | Increased IgM level (HP:0003496) | 2.40857813 |
48 | Prominent nose (HP:0000448) | 2.39461511 |
49 | Systemic lupus erythematosus (HP:0002725) | 2.39404052 |
50 | Peritonitis (HP:0002586) | 2.36554890 |
51 | Osteomyelitis (HP:0002754) | 2.33316856 |
52 | Keratoconjunctivitis sicca (HP:0001097) | 2.32280821 |
53 | Vacuolated lymphocytes (HP:0001922) | 2.32156584 |
54 | Myocardial infarction (HP:0001658) | 2.29793494 |
55 | Autoimmune hemolytic anemia (HP:0001890) | 2.29440756 |
56 | Abnormality of T cells (HP:0002843) | 2.28950771 |
57 | Absent frontal sinuses (HP:0002688) | 2.25955726 |
58 | Meningitis (HP:0001287) | 2.24656334 |
59 | Premature loss of primary teeth (HP:0006323) | 2.22324125 |
60 | Transitional cell carcinoma of the bladder (HP:0006740) | 2.21683603 |
61 | Macroorchidism (HP:0000053) | 2.21377272 |
62 | Eosinophilia (HP:0001880) | 2.17914120 |
63 | Pustule (HP:0200039) | 2.17727292 |
64 | Joint hemorrhage (HP:0005261) | 2.16941056 |
65 | Hemoptysis (HP:0002105) | 2.15802040 |
66 | Cellulitis (HP:0100658) | 2.12983709 |
67 | Prolonged bleeding time (HP:0003010) | 2.12849962 |
68 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.12027814 |
69 | Bladder carcinoma (HP:0002862) | 2.11487439 |
70 | Bladder neoplasm (HP:0009725) | 2.11487439 |
71 | Asymmetry of the thorax (HP:0001555) | 2.11382720 |
72 | Keratoconjunctivitis (HP:0001096) | 2.11243604 |
73 | Alveolar cell carcinoma (HP:0006519) | 2.09408340 |
74 | Thyroid carcinoma (HP:0002890) | 2.09204804 |
75 | Recurrent bronchitis (HP:0002837) | 2.08170824 |
76 | Clubbing of toes (HP:0100760) | 2.07836306 |
77 | Narrow palate (HP:0000189) | 2.06516241 |
78 | Hematochezia (HP:0002573) | 2.06352583 |
79 | Hypergammaglobulinemia (HP:0010702) | 2.05278038 |
80 | Abnormality of B cell number (HP:0010975) | 2.03901181 |
81 | Stomach cancer (HP:0012126) | 2.02046140 |
82 | Bone pain (HP:0002653) | 2.01256972 |
83 | IgM deficiency (HP:0002850) | 2.00700551 |
84 | Acute lymphatic leukemia (HP:0006721) | 2.00147680 |
85 | Spinal cord lesions (HP:0100561) | 2.00144384 |
86 | Syringomyelia (HP:0003396) | 2.00144384 |
87 | Leukocytosis (HP:0001974) | 1.99730648 |
88 | IgA deficiency (HP:0002720) | 1.99540525 |
89 | Papilledema (HP:0001085) | 1.95805469 |
90 | B lymphocytopenia (HP:0010976) | 1.94213638 |
91 | Abnormality of T cell physiology (HP:0011840) | 1.93920290 |
92 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.93025115 |
93 | Abnormality of the nasal septum (HP:0000419) | 1.93007363 |
94 | Vertebral compression fractures (HP:0002953) | 1.92810017 |
95 | Gastrointestinal infarctions (HP:0005244) | 1.91837708 |
96 | Rhabdomyosarcoma (HP:0002859) | 1.89814279 |
97 | Cheilitis (HP:0100825) | 1.89475062 |
98 | Low anterior hairline (HP:0000294) | 1.89467650 |
99 | Vertebral arch anomaly (HP:0008438) | 1.89090984 |
100 | Interstitial pulmonary disease (HP:0006530) | 1.87686841 |
101 | Nephritis (HP:0000123) | 1.87418275 |
102 | Porencephaly (HP:0002132) | 1.87036714 |
103 | Stomatitis (HP:0010280) | 1.86655556 |
104 | Abnormality of incisor morphology (HP:0011063) | 1.86199769 |
105 | Anal stenosis (HP:0002025) | 1.86096724 |
106 | Plagiocephaly (HP:0001357) | 1.85292592 |
107 | Progressive inability to walk (HP:0002505) | 1.84952625 |
108 | Thrombocytosis (HP:0001894) | 1.84129792 |
109 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.83994950 |
110 | Granulocytopenia (HP:0001913) | 1.83356437 |
111 | Poikiloderma (HP:0001029) | 1.83181674 |
112 | Inflammation of the large intestine (HP:0002037) | 1.83138918 |
113 | Abnormality of the endocardium (HP:0004306) | 1.82783218 |
114 | Overgrowth (HP:0001548) | 1.82624724 |
115 | Acute myeloid leukemia (HP:0004808) | 1.82499264 |
116 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.82442290 |
117 | Renal cortical cysts (HP:0000803) | 1.81849810 |
118 | Epistaxis (HP:0000421) | 1.81848758 |
119 | Nasal polyposis (HP:0100582) | 1.81826463 |
120 | Spontaneous hematomas (HP:0007420) | 1.81801221 |
121 | Chronic sinusitis (HP:0011109) | 1.81413892 |
122 | Abnormality of the fingertips (HP:0001211) | 1.80913897 |
123 | Agammaglobulinemia (HP:0004432) | 1.80668559 |
124 | Spondylolisthesis (HP:0003302) | 1.80198233 |
125 | Abnormality of T cell number (HP:0011839) | 1.79902880 |
126 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.79881316 |
127 | Medulloblastoma (HP:0002885) | 1.79737862 |
128 | Abnormality of the pleura (HP:0002103) | 1.79436265 |
129 | Arterial tortuosity (HP:0005116) | 1.78572975 |
130 | Abnormality of the pericardium (HP:0001697) | 1.78482695 |
131 | Abnormality of the frontal sinuses (HP:0002687) | 1.77977819 |
132 | Panhypogammaglobulinemia (HP:0003139) | 1.77922082 |
133 | Encephalitis (HP:0002383) | 1.77898787 |
134 | Abnormal auditory evoked potentials (HP:0006958) | 1.77647226 |
135 | Albinism (HP:0001022) | 1.76964930 |
136 | Bronchitis (HP:0012387) | 1.76951612 |
137 | Abnormal platelet volume (HP:0011876) | 1.75267924 |
138 | Thyroiditis (HP:0100646) | 1.74337305 |
139 | Colitis (HP:0002583) | 1.74064398 |
140 | Bruising susceptibility (HP:0000978) | 1.73835455 |
141 | Thoracolumbar scoliosis (HP:0002944) | 1.73623356 |
142 | Petechiae (HP:0000967) | 1.73183938 |
143 | Menstrual irregularities (HP:0000858) | 1.72903671 |
144 | Abnormality of the peritoneum (HP:0002585) | 1.72600508 |
145 | Glomerulopathy (HP:0100820) | 1.72005583 |
146 | Gangrene (HP:0100758) | 1.71986011 |
147 | Persistence of primary teeth (HP:0006335) | 1.70154987 |
148 | Curly hair (HP:0002212) | 1.68861174 |
149 | Micronodular cirrhosis (HP:0001413) | 1.67157017 |
150 | Somatic mutation (HP:0001428) | 1.66342235 |
151 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.65505399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K14 | 4.46520378 |
2 | TYK2 | 3.22840860 |
3 | IRAK4 | 2.79355853 |
4 | IKBKE | 2.75274399 |
5 | TXK | 2.65816404 |
6 | BLK | 2.54713673 |
7 | JAK3 | 2.52004075 |
8 | TBK1 | 2.46296081 |
9 | IRAK3 | 2.34221262 |
10 | KIT | 2.28141152 |
11 | IKBKB | 2.12058770 |
12 | * JAK1 | 2.06968217 |
13 | ZAK | 1.81854619 |
14 | NEK9 | 1.81577501 |
15 | TEC | 1.81030868 |
16 | MAP4K1 | 1.80234743 |
17 | EIF2AK3 | 1.80066096 |
18 | TRIM28 | 1.79727603 |
19 | FGFR4 | 1.74535319 |
20 | EPHA3 | 1.74138098 |
21 | MAP3K13 | 1.67566544 |
22 | FGFR3 | 1.65285444 |
23 | FRK | 1.64231021 |
24 | ACVR1B | 1.61495710 |
25 | CHUK | 1.60587686 |
26 | TRPM7 | 1.59144792 |
27 | TGFBR2 | 1.55028895 |
28 | CAMK1D | 1.53656369 |
29 | RIPK4 | 1.52199711 |
30 | NUAK1 | 1.51493862 |
31 | TAOK3 | 1.50702329 |
32 | MELK | 1.44100910 |
33 | PBK | 1.42044935 |
34 | BCR | 1.40338593 |
35 | CDK12 | 1.36662901 |
36 | SIK3 | 1.33869409 |
37 | PIM2 | 1.27892545 |
38 | YES1 | 1.27454524 |
39 | TNIK | 1.23016309 |
40 | INSRR | 1.22246162 |
41 | STK3 | 1.20514416 |
42 | CSK | 1.20163762 |
43 | HCK | 1.14090515 |
44 | CSF1R | 1.13011576 |
45 | STK38L | 1.12482260 |
46 | AKT3 | 1.11374057 |
47 | BTK | 1.05951649 |
48 | PIM1 | 1.03828741 |
49 | ZAP70 | 1.02299883 |
50 | SYK | 1.01869471 |
51 | STK4 | 0.99374739 |
52 | LYN | 0.99032375 |
53 | IRAK1 | 0.96859840 |
54 | PIK3CG | 0.94203323 |
55 | BRSK2 | 0.93138833 |
56 | * EIF2AK2 | 0.91719393 |
57 | LCK | 0.90366595 |
58 | MAP3K2 | 0.89807185 |
59 | PIK3CA | 0.89806583 |
60 | TSSK6 | 0.88825209 |
61 | TIE1 | 0.83153855 |
62 | RPS6KA4 | 0.83153807 |
63 | ERN1 | 0.82553740 |
64 | MARK3 | 0.81849707 |
65 | BMPR2 | 0.81705609 |
66 | WNK1 | 0.81682401 |
67 | SIK1 | 0.80205907 |
68 | EPHB1 | 0.75956907 |
69 | STK10 | 0.75804911 |
70 | FGFR2 | 0.74911254 |
71 | PDGFRA | 0.74106967 |
72 | CAMK1G | 0.74041748 |
73 | NLK | 0.73635841 |
74 | BRD4 | 0.71853339 |
75 | SCYL2 | 0.71698511 |
76 | JAK2 | 0.71097075 |
77 | TAF1 | 0.70098592 |
78 | MKNK2 | 0.69499597 |
79 | RPS6KB2 | 0.69092238 |
80 | TTN | 0.68767216 |
81 | ERBB3 | 0.68183948 |
82 | ITK | 0.68126819 |
83 | MAP2K3 | 0.66641540 |
84 | MST1R | 0.66059915 |
85 | STK38 | 0.64499425 |
86 | PRKAA2 | 0.63293388 |
87 | CAMKK2 | 0.62466403 |
88 | ABL1 | 0.61825445 |
89 | MATK | 0.61010353 |
90 | ATR | 0.60822471 |
91 | HIPK2 | 0.60733750 |
92 | BMX | 0.60281737 |
93 | MAP3K6 | 0.60202394 |
94 | GRK1 | 0.58828686 |
95 | PRPF4B | 0.58514061 |
96 | LATS1 | 0.58505491 |
97 | PRKCQ | 0.58428718 |
98 | MST4 | 0.57312177 |
99 | FLT3 | 0.56714058 |
100 | BMPR1B | 0.55824851 |
101 | CDC7 | 0.55026605 |
102 | ADRBK2 | 0.52794069 |
103 | FER | 0.52706773 |
104 | CDK6 | 0.52548002 |
105 | SIK2 | 0.52387955 |
106 | STK24 | 0.51684564 |
107 | RIPK1 | 0.50988419 |
108 | MAP3K3 | 0.50652185 |
109 | CLK1 | 0.50098116 |
110 | RPS6KA5 | 0.49904378 |
111 | PTK6 | 0.47312138 |
112 | STK39 | 0.47215844 |
113 | MAP3K10 | 0.46983918 |
114 | EIF2AK1 | 0.46351674 |
115 | FGR | 0.45466503 |
116 | SGK2 | 0.44535547 |
117 | GRK7 | 0.44459188 |
118 | IRAK2 | 0.41965717 |
119 | PRKG2 | 0.40867092 |
120 | EGFR | 0.40742168 |
121 | TGFBR1 | 0.40615651 |
122 | PRKCD | 0.40511327 |
123 | MAP3K5 | 0.39667286 |
124 | DDR2 | 0.39145861 |
125 | IGF1R | 0.39042588 |
126 | SGK3 | 0.38913236 |
127 | CDC42BPA | 0.38672870 |
128 | PTK2B | 0.38623466 |
129 | KSR1 | 0.38441804 |
130 | CDK4 | 0.37851972 |
131 | TNK2 | 0.37715141 |
132 | PLK4 | 0.36231738 |
133 | FGFR1 | 0.35755416 |
134 | MAPK11 | 0.34446261 |
135 | INSR | 0.33055544 |
136 | MKNK1 | 0.32368218 |
137 | PDGFRB | 0.32288508 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.86345427 |
2 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.85597513 |
3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.70730058 |
4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.64964258 |
5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.61385219 |
6 | Allograft rejection_Homo sapiens_hsa05330 | 2.59506207 |
7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.53582845 |
8 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.52180921 |
9 | * Measles_Homo sapiens_hsa05162 | 2.50254715 |
10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.30160097 |
11 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.18813294 |
12 | Malaria_Homo sapiens_hsa05144 | 2.17854005 |
13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.14769177 |
14 | * Influenza A_Homo sapiens_hsa05164 | 2.07257102 |
15 | * Herpes simplex infection_Homo sapiens_hsa05168 | 2.01395242 |
16 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.99155965 |
17 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.93586041 |
18 | Legionellosis_Homo sapiens_hsa05134 | 1.82711782 |
19 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.73797837 |
20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71305823 |
21 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.68737825 |
22 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.61353603 |
23 | Pertussis_Homo sapiens_hsa05133 | 1.60742504 |
24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.59032354 |
25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.57974782 |
26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.57797244 |
27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.53266516 |
28 | Tuberculosis_Homo sapiens_hsa05152 | 1.52948092 |
29 | Asthma_Homo sapiens_hsa05310 | 1.46964357 |
30 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.35770748 |
31 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.35319611 |
32 | Apoptosis_Homo sapiens_hsa04210 | 1.30140712 |
33 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.29203826 |
34 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.24286261 |
35 | Hepatitis B_Homo sapiens_hsa05161 | 1.22764044 |
36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.21909708 |
37 | * Hepatitis C_Homo sapiens_hsa05160 | 1.21062643 |
38 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.20064658 |
39 | Viral myocarditis_Homo sapiens_hsa05416 | 1.18067158 |
40 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.12660651 |
41 | Salmonella infection_Homo sapiens_hsa05132 | 1.12070150 |
42 | Phagosome_Homo sapiens_hsa04145 | 1.12018247 |
43 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.10024833 |
44 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.06700187 |
45 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.05585286 |
46 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.05191468 |
47 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.02620362 |
48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.96798643 |
49 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.96317648 |
50 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.96264643 |
51 | Other glycan degradation_Homo sapiens_hsa00511 | 0.94180634 |
52 | Shigellosis_Homo sapiens_hsa05131 | 0.85115881 |
53 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.84394151 |
54 | Amoebiasis_Homo sapiens_hsa05146 | 0.80782905 |
55 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.80170764 |
56 | ABC transporters_Homo sapiens_hsa02010 | 0.80016680 |
57 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.79455014 |
58 | Lysosome_Homo sapiens_hsa04142 | 0.79162534 |
59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.78560587 |
60 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.78396340 |
61 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.73481390 |
62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.72067143 |
63 | Glioma_Homo sapiens_hsa05214 | 0.72043560 |
64 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.71455959 |
65 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.71344484 |
66 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.69687823 |
67 | Endometrial cancer_Homo sapiens_hsa05213 | 0.69259828 |
68 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.69015833 |
69 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.68290623 |
70 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.68182562 |
71 | Colorectal cancer_Homo sapiens_hsa05210 | 0.68004190 |
72 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.66940478 |
73 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.66448475 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.66322519 |
75 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.66284280 |
76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65367556 |
77 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.64771350 |
78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.63102062 |
79 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.63077522 |
80 | Thyroid cancer_Homo sapiens_hsa05216 | 0.62801407 |
81 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.62249160 |
82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.61151967 |
83 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.57946475 |
84 | Platelet activation_Homo sapiens_hsa04611 | 0.57850873 |
85 | Pathways in cancer_Homo sapiens_hsa05200 | 0.56009370 |
86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.55686647 |
87 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.52916372 |
88 | * Viral carcinogenesis_Homo sapiens_hsa05203 | 0.52286291 |
89 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.51440735 |
90 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.50762607 |
91 | Adherens junction_Homo sapiens_hsa04520 | 0.50341146 |
92 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50165701 |
93 | Insulin resistance_Homo sapiens_hsa04931 | 0.49496706 |
94 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.48037945 |
95 | HTLV-I infection_Homo sapiens_hsa05166 | 0.47880529 |
96 | Focal adhesion_Homo sapiens_hsa04510 | 0.46788084 |
97 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.46027327 |
98 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.44468927 |
99 | Bladder cancer_Homo sapiens_hsa05219 | 0.44266257 |
100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43924688 |
101 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.43459513 |
102 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.42521292 |
103 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.42181881 |
104 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.40934081 |
105 | Lysine degradation_Homo sapiens_hsa00310 | 0.40146674 |
106 | Cell cycle_Homo sapiens_hsa04110 | 0.39919199 |
107 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39710078 |
108 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39588161 |
109 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.39143566 |
110 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.38620571 |
111 | Prostate cancer_Homo sapiens_hsa05215 | 0.38450799 |
112 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.38386187 |
113 | * Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38360656 |
114 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37137690 |
115 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.36918114 |
116 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.36718303 |
117 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.33477643 |
118 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.33027136 |
119 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.32897459 |
120 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.31790119 |
121 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.31424876 |
122 | Melanoma_Homo sapiens_hsa05218 | 0.30761583 |
123 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.30695320 |
124 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.29835384 |
125 | Mineral absorption_Homo sapiens_hsa04978 | 0.29193183 |
126 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28751129 |
127 | Homologous recombination_Homo sapiens_hsa03440 | 0.27889867 |