Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 5.32239542 |
2 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.84397289 |
3 | nuclear pore organization (GO:0006999) | 4.74270258 |
4 | nuclear pore complex assembly (GO:0051292) | 4.61556205 |
5 | Golgi transport vesicle coating (GO:0048200) | 4.45126923 |
6 | COPI coating of Golgi vesicle (GO:0048205) | 4.45126923 |
7 | protein localization to kinetochore (GO:0034501) | 4.43958694 |
8 | heterochromatin organization (GO:0070828) | 4.35661228 |
9 | mitotic nuclear envelope disassembly (GO:0007077) | 4.29164106 |
10 | regulation of translational fidelity (GO:0006450) | 4.08051296 |
11 | proline biosynthetic process (GO:0006561) | 4.04655877 |
12 | membrane disassembly (GO:0030397) | 4.02681964 |
13 | nuclear envelope disassembly (GO:0051081) | 4.02681964 |
14 | IMP biosynthetic process (GO:0006188) | 4.01221028 |
15 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.92991615 |
16 | nucleobase biosynthetic process (GO:0046112) | 3.91874659 |
17 | DNA replication initiation (GO:0006270) | 3.91022247 |
18 | * formation of translation preinitiation complex (GO:0001731) | 3.87412705 |
19 | protein complex localization (GO:0031503) | 3.87007668 |
20 | maturation of SSU-rRNA (GO:0030490) | 3.76901140 |
21 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.75734482 |
22 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.75734482 |
23 | cellular protein complex localization (GO:0034629) | 3.75103622 |
24 | protein localization to chromosome, centromeric region (GO:0071459) | 3.74957605 |
25 | regulation of translational termination (GO:0006449) | 3.71589820 |
26 | DNA strand elongation (GO:0022616) | 3.70090174 |
27 | DNA duplex unwinding (GO:0032508) | 3.58368405 |
28 | IMP metabolic process (GO:0046040) | 3.57804720 |
29 | DNA geometric change (GO:0032392) | 3.55421947 |
30 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.48273241 |
31 | regulation of gene silencing by miRNA (GO:0060964) | 3.48273241 |
32 | regulation of gene silencing by RNA (GO:0060966) | 3.48273241 |
33 | pore complex assembly (GO:0046931) | 3.44939214 |
34 | pre-miRNA processing (GO:0031054) | 3.44112134 |
35 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.43391275 |
36 | viral transcription (GO:0019083) | 3.42598414 |
37 | translational termination (GO:0006415) | 3.41444543 |
38 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.37779408 |
39 | DNA topological change (GO:0006265) | 3.33145895 |
40 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.29489077 |
41 | nuclear envelope organization (GO:0006998) | 3.27164230 |
42 | * translational initiation (GO:0006413) | 3.26147240 |
43 | ribosome assembly (GO:0042255) | 3.24619127 |
44 | purine nucleobase biosynthetic process (GO:0009113) | 3.24576079 |
45 | protein export from nucleus (GO:0006611) | 3.24353888 |
46 | translational elongation (GO:0006414) | 3.23894240 |
47 | chromatin assembly (GO:0031497) | 3.23721027 |
48 | ribosomal small subunit assembly (GO:0000028) | 3.22353382 |
49 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.21618575 |
50 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.19580582 |
51 | mitotic chromosome condensation (GO:0007076) | 3.16764354 |
52 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.16469698 |
53 | mRNA stabilization (GO:0048255) | 3.15345273 |
54 | RNA stabilization (GO:0043489) | 3.15345273 |
55 | mitotic sister chromatid segregation (GO:0000070) | 3.14712933 |
56 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.14682973 |
57 | establishment of integrated proviral latency (GO:0075713) | 3.12990603 |
58 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.12896210 |
59 | mitotic metaphase plate congression (GO:0007080) | 3.12750621 |
60 | regulation of histone H3-K9 methylation (GO:0051570) | 3.09643202 |
61 | sister chromatid segregation (GO:0000819) | 3.08607674 |
62 | negative regulation of RNA splicing (GO:0033119) | 3.07807144 |
63 | pentose-phosphate shunt (GO:0006098) | 3.06834918 |
64 | dosage compensation (GO:0007549) | 3.05583297 |
65 | ribosome biogenesis (GO:0042254) | 3.05477799 |
66 | folic acid metabolic process (GO:0046655) | 3.02886542 |
67 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.02130379 |
68 | regulation of spindle organization (GO:0090224) | 3.00589141 |
69 | DNA replication checkpoint (GO:0000076) | 2.98664337 |
70 | activation of Rac GTPase activity (GO:0032863) | 2.98338095 |
71 | focal adhesion assembly (GO:0048041) | 2.97025027 |
72 | cell-substrate adherens junction assembly (GO:0007045) | 2.97025027 |
73 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.96594004 |
74 | adherens junction assembly (GO:0034333) | 2.93956339 |
75 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.93376213 |
76 | chaperone-mediated protein complex assembly (GO:0051131) | 2.91880757 |
77 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.91627789 |
78 | negative regulation of mRNA metabolic process (GO:1903312) | 2.91594477 |
79 | positive regulation of chromosome segregation (GO:0051984) | 2.91002370 |
80 | ribosomal large subunit biogenesis (GO:0042273) | 2.89905666 |
81 | negative regulation of histone methylation (GO:0031061) | 2.89324560 |
82 | DNA conformation change (GO:0071103) | 2.89308986 |
83 | negative regulation of mRNA processing (GO:0050686) | 2.89302856 |
84 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.88159295 |
85 | regulation of histone H3-K27 methylation (GO:0061085) | 2.87249404 |
86 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.86766673 |
87 | translesion synthesis (GO:0019985) | 2.84735490 |
88 | tetrahydrofolate metabolic process (GO:0046653) | 2.84278325 |
89 | protein retention in ER lumen (GO:0006621) | 2.83064919 |
90 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.82340019 |
91 | rRNA transcription (GO:0009303) | 2.79533925 |
92 | telomere maintenance via recombination (GO:0000722) | 2.78085537 |
93 | mitotic sister chromatid cohesion (GO:0007064) | 2.77076264 |
94 | mitotic recombination (GO:0006312) | 2.76455438 |
95 | peptidyl-lysine dimethylation (GO:0018027) | 2.76368278 |
96 | DNA synthesis involved in DNA repair (GO:0000731) | 2.76149990 |
97 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.76002380 |
98 | chromatin assembly or disassembly (GO:0006333) | 2.75297313 |
99 | protein-DNA complex disassembly (GO:0032986) | 2.74413080 |
100 | nucleosome disassembly (GO:0006337) | 2.74413080 |
101 | gene silencing by RNA (GO:0031047) | 2.73958747 |
102 | maternal placenta development (GO:0001893) | 2.73899809 |
103 | protein localization to chromosome (GO:0034502) | 2.73796511 |
104 | regulation of RNA export from nucleus (GO:0046831) | 2.73113651 |
105 | histone arginine methylation (GO:0034969) | 2.72592384 |
106 | DNA packaging (GO:0006323) | 2.72113773 |
107 | chromosome condensation (GO:0030261) | 2.71575919 |
108 | NADPH regeneration (GO:0006740) | 2.69380071 |
109 | peptidyl-arginine methylation (GO:0018216) | 2.69225529 |
110 | peptidyl-arginine N-methylation (GO:0035246) | 2.69225529 |
111 | regulation of hippo signaling (GO:0035330) | 2.68971145 |
112 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.68633126 |
113 | cellular protein complex disassembly (GO:0043624) | 2.68377764 |
114 | metaphase plate congression (GO:0051310) | 2.68287250 |
115 | ribosomal small subunit biogenesis (GO:0042274) | 2.65573606 |
116 | protein complex disassembly (GO:0043241) | 2.65355578 |
117 | regulation of mitotic spindle organization (GO:0060236) | 2.65199201 |
118 | apoptotic process involved in morphogenesis (GO:0060561) | 2.65075847 |
119 | viral life cycle (GO:0019058) | 2.64351905 |
120 | mRNA splicing, via spliceosome (GO:0000398) | 2.63854850 |
121 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.63854850 |
122 | regulation of sister chromatid cohesion (GO:0007063) | 2.63572483 |
123 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.63411979 |
124 | RNA splicing, via transesterification reactions (GO:0000375) | 2.62516303 |
125 | mRNA transport (GO:0051028) | 2.62098011 |
126 | telomere maintenance via telomere lengthening (GO:0010833) | 2.61014016 |
127 | protein targeting to ER (GO:0045047) | 2.60959173 |
128 | gene silencing (GO:0016458) | 2.59131249 |
129 | regulation of translational elongation (GO:0006448) | 2.58999329 |
130 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.58701297 |
131 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.58528149 |
132 | viral mRNA export from host cell nucleus (GO:0046784) | 2.57598834 |
133 | glucose catabolic process (GO:0006007) | 2.56574708 |
134 | proline metabolic process (GO:0006560) | 2.56066797 |
135 | mitochondrial DNA metabolic process (GO:0032042) | 2.52967088 |
136 | cell-substrate junction assembly (GO:0007044) | 2.52395297 |
137 | negative regulation of cell size (GO:0045792) | 2.51051152 |
138 | regulation of early endosome to late endosome transport (GO:2000641) | 2.47133966 |
139 | positive regulation of nuclease activity (GO:0032075) | 2.46896206 |
140 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.45040328 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.81126491 |
2 | * FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.96106312 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.73267188 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.72546481 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.95378782 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.84673926 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.80247070 |
8 | MYC_22102868_ChIP-Seq_BL_Human | 2.73446137 |
9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.65644239 |
10 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.33249717 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.22569865 |
12 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.20243060 |
13 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.05335470 |
14 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.05041787 |
15 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.02138272 |
16 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.94292456 |
17 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.82036091 |
18 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.81729487 |
19 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.70907433 |
20 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.70615518 |
21 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.67650721 |
22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.64675345 |
23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.64167527 |
24 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.58837747 |
25 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.54202211 |
26 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.53817396 |
27 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.51945001 |
28 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.51106352 |
29 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51083968 |
30 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.49993308 |
31 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.49790971 |
32 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.48296224 |
33 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.47939646 |
34 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.47210834 |
35 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.46079246 |
36 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.45732566 |
37 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.45079354 |
38 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.44695363 |
39 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.43524781 |
40 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.42707969 |
41 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.42488382 |
42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.42005712 |
43 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.40066830 |
44 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39528347 |
45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.39266370 |
46 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.34665082 |
47 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.34523237 |
48 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.31742145 |
49 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.31099811 |
50 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.30728933 |
51 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.30201596 |
52 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.28981108 |
53 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.28256223 |
54 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.27622574 |
55 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.27231799 |
56 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.26609046 |
57 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.24787944 |
58 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.24536823 |
59 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.21685697 |
60 | * TFEB_21752829_ChIP-Seq_HELA_Human | 1.20402338 |
61 | * PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.20035830 |
62 | ATF3_27146783_Chip-Seq_COLON_Human | 1.19709872 |
63 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.18709612 |
64 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.15769465 |
65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.15757814 |
66 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.15541345 |
67 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.14001759 |
68 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.10296025 |
69 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.10271704 |
70 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.09902984 |
71 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.09651392 |
72 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09633760 |
73 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.08486689 |
74 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07301966 |
75 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.05802233 |
76 | MAF_26560356_Chip-Seq_TH1_Human | 1.05572132 |
77 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.05011568 |
78 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.04590950 |
79 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.04063206 |
80 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.03691380 |
81 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.03531696 |
82 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.03484770 |
83 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03450289 |
84 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03374752 |
85 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.03197167 |
86 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03098538 |
87 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.02253579 |
88 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.01078235 |
89 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.01002345 |
90 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.00383850 |
91 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.99457691 |
92 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.98545151 |
93 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.98474399 |
94 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.98250238 |
95 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.97673619 |
96 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.96458817 |
97 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.96296271 |
98 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.96106456 |
99 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.95500544 |
100 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.95213716 |
101 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.93137541 |
102 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.92936213 |
103 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.92789963 |
104 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.92541855 |
105 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.92541855 |
106 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.92541855 |
107 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.92506969 |
108 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.90186356 |
109 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.89812756 |
110 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.89644098 |
111 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.89095220 |
112 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.88813418 |
113 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.88764072 |
114 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.88520008 |
115 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.88389631 |
116 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.88338230 |
117 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.87750338 |
118 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.85725951 |
119 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.85297071 |
120 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.85193010 |
121 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.84448926 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.71105114 |
2 | MP0010352_gastrointestinal_tract_polyps | 3.45221360 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.43530023 |
4 | MP0003111_abnormal_nucleus_morphology | 3.40201582 |
5 | MP0003705_abnormal_hypodermis_morpholog | 3.13988159 |
6 | MP0010094_abnormal_chromosome_stability | 3.09369247 |
7 | MP0003077_abnormal_cell_cycle | 2.89616584 |
8 | MP0005451_abnormal_body_composition | 2.61430223 |
9 | MP0001730_embryonic_growth_arrest | 2.47852742 |
10 | MP0008057_abnormal_DNA_replication | 2.37924695 |
11 | MP0010307_abnormal_tumor_latency | 2.19626366 |
12 | MP0005076_abnormal_cell_differentiation | 2.16746082 |
13 | MP0000350_abnormal_cell_proliferation | 2.08693688 |
14 | MP0008007_abnormal_cellular_replicative | 2.03079914 |
15 | MP0002396_abnormal_hematopoietic_system | 1.88420461 |
16 | MP0003123_paternal_imprinting | 1.86459741 |
17 | MP0004197_abnormal_fetal_growth/weight/ | 1.82544564 |
18 | MP0001672_abnormal_embryogenesis/_devel | 1.81908943 |
19 | MP0005380_embryogenesis_phenotype | 1.81908943 |
20 | MP0003566_abnormal_cell_adhesion | 1.78090499 |
21 | MP0003984_embryonic_growth_retardation | 1.72721693 |
22 | MP0001697_abnormal_embryo_size | 1.71303970 |
23 | MP0002088_abnormal_embryonic_growth/wei | 1.70250746 |
24 | MP0000537_abnormal_urethra_morphology | 1.68044884 |
25 | MP0008932_abnormal_embryonic_tissue | 1.68027451 |
26 | MP0002084_abnormal_developmental_patter | 1.66222031 |
27 | MP0000490_abnormal_crypts_of | 1.64932785 |
28 | MP0002080_prenatal_lethality | 1.64181209 |
29 | MP0002086_abnormal_extraembryonic_tissu | 1.63005872 |
30 | MP0008058_abnormal_DNA_repair | 1.62949994 |
31 | MP0002085_abnormal_embryonic_tissue | 1.57074643 |
32 | MP0009278_abnormal_bone_marrow | 1.56151110 |
33 | MP0004808_abnormal_hematopoietic_stem | 1.55029764 |
34 | MP0001849_ear_inflammation | 1.52613765 |
35 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46902762 |
36 | MP0008260_abnormal_autophagy | 1.41340942 |
37 | MP0005023_abnormal_wound_healing | 1.39851619 |
38 | MP0009053_abnormal_anal_canal | 1.38846051 |
39 | MP0002060_abnormal_skin_morphology | 1.38197556 |
40 | MP0005058_abnormal_lysosome_morphology | 1.37271580 |
41 | MP0004858_abnormal_nervous_system | 1.36303075 |
42 | MP0001661_extended_life_span | 1.35123941 |
43 | MP0010234_abnormal_vibrissa_follicle | 1.32982441 |
44 | MP0003941_abnormal_skin_development | 1.29868416 |
45 | MP0010030_abnormal_orbit_morphology | 1.29038480 |
46 | MP0004272_abnormal_basement_membrane | 1.28542513 |
47 | MP0002877_abnormal_melanocyte_morpholog | 1.27902800 |
48 | MP0005257_abnormal_intraocular_pressure | 1.27469873 |
49 | MP0008877_abnormal_DNA_methylation | 1.27435436 |
50 | MP0000678_abnormal_parathyroid_gland | 1.26892273 |
51 | MP0002019_abnormal_tumor_incidence | 1.26512884 |
52 | MP0005397_hematopoietic_system_phenotyp | 1.26053865 |
53 | MP0001545_abnormal_hematopoietic_system | 1.26053865 |
54 | MP0000733_abnormal_muscle_development | 1.24997458 |
55 | MP0006054_spinal_hemorrhage | 1.22303580 |
56 | MP0003300_gastrointestinal_ulcer | 1.22191367 |
57 | MP0000313_abnormal_cell_death | 1.20416573 |
58 | MP0001915_intracranial_hemorrhage | 1.14390996 |
59 | MP0001348_abnormal_lacrimal_gland | 1.14293931 |
60 | MP0002009_preneoplasia | 1.13412573 |
61 | MP0003806_abnormal_nucleotide_metabolis | 1.13098513 |
62 | MP0009672_abnormal_birth_weight | 1.11055900 |
63 | MP0004185_abnormal_adipocyte_glucose | 1.10828341 |
64 | MP0009333_abnormal_splenocyte_physiolog | 1.10511885 |
65 | MP0003119_abnormal_digestive_system | 1.07650465 |
66 | MP0003786_premature_aging | 1.06702072 |
67 | MP0003091_abnormal_cell_migration | 1.04522182 |
68 | MP0000003_abnormal_adipose_tissue | 1.03957511 |
69 | MP0000579_abnormal_nail_morphology | 1.03472133 |
70 | MP0000858_altered_metastatic_potential | 0.99657133 |
71 | MP0005623_abnormal_meninges_morphology | 0.97827212 |
72 | MP0003303_peritoneal_inflammation | 0.97327985 |
73 | MP0005409_darkened_coat_color | 0.97198068 |
74 | MP0000703_abnormal_thymus_morphology | 0.96651174 |
75 | MP0005375_adipose_tissue_phenotype | 0.94210424 |
76 | MP0003115_abnormal_respiratory_system | 0.93350604 |
77 | MP0005501_abnormal_skin_physiology | 0.92818180 |
78 | MP0008438_abnormal_cutaneous_collagen | 0.91192485 |
79 | MP0000747_muscle_weakness | 0.90909015 |
80 | MP0002653_abnormal_ependyma_morphology | 0.90445808 |
81 | MP0002098_abnormal_vibrissa_morphology | 0.90347783 |
82 | MP0003221_abnormal_cardiomyocyte_apopto | 0.89604064 |
83 | MP0000477_abnormal_intestine_morphology | 0.88855475 |
84 | MP0003315_abnormal_perineum_morphology | 0.88751208 |
85 | MP0001293_anophthalmia | 0.88443579 |
86 | MP0000627_abnormal_mammary_gland | 0.88440073 |
87 | MP0000428_abnormal_craniofacial_morphol | 0.88116895 |
88 | MP0000377_abnormal_hair_follicle | 0.87466528 |
89 | MP0003763_abnormal_thymus_physiology | 0.86185122 |
90 | MP0002111_abnormal_tail_morphology | 0.85917668 |
91 | MP0003890_abnormal_embryonic-extraembry | 0.85309737 |
92 | MP0001881_abnormal_mammary_gland | 0.84128272 |
93 | MP0009931_abnormal_skin_appearance | 0.84053817 |
94 | MP0002210_abnormal_sex_determination | 0.83404770 |
95 | MP0009703_decreased_birth_body | 0.83322717 |
96 | MP0000762_abnormal_tongue_morphology | 0.83284871 |
97 | MP0002722_abnormal_immune_system | 0.83135094 |
98 | MP0000358_abnormal_cell_content/ | 0.83012067 |
99 | MP0002398_abnormal_bone_marrow | 0.81902155 |
100 | MP0000467_abnormal_esophagus_morphology | 0.81506500 |
101 | MP0004233_abnormal_muscle_weight | 0.80955185 |
102 | MP0001145_abnormal_male_reproductive | 0.80812112 |
103 | MP0002092_abnormal_eye_morphology | 0.80785479 |
104 | MP0002697_abnormal_eye_size | 0.80430773 |
105 | MP0000750_abnormal_muscle_regeneration | 0.80274305 |
106 | MP0004264_abnormal_extraembryonic_tissu | 0.79526882 |
107 | MP0002925_abnormal_cardiovascular_devel | 0.78389404 |
108 | MP0005621_abnormal_cell_physiology | 0.77636549 |
109 | MP0004782_abnormal_surfactant_physiolog | 0.76938803 |
110 | MP0008770_decreased_survivor_rate | 0.76436038 |
111 | MP0000689_abnormal_spleen_morphology | 0.74423404 |
112 | MP0001727_abnormal_embryo_implantation | 0.74190686 |
113 | MP0001346_abnormal_lacrimal_gland | 0.73533825 |
114 | MP0000759_abnormal_skeletal_muscle | 0.73330150 |
115 | MP0004087_abnormal_muscle_fiber | 0.72315914 |
116 | MP0004947_skin_inflammation | 0.72062906 |
117 | MP0005384_cellular_phenotype | 0.72017830 |
118 | MP0001929_abnormal_gametogenesis | 0.71232845 |
119 | MP0003283_abnormal_digestive_organ | 0.70527270 |
120 | MP0010630_abnormal_cardiac_muscle | 0.70260693 |
121 | MP0005666_abnormal_adipose_tissue | 0.69013552 |
122 | MP0002796_impaired_skin_barrier | 0.68984342 |
123 | MP0003448_altered_tumor_morphology | 0.68123606 |
124 | MP0003453_abnormal_keratinocyte_physiol | 0.67776949 |
125 | MP0009840_abnormal_foam_cell | 0.67720396 |
126 | MP0000598_abnormal_liver_morphology | 0.65241084 |
127 | MP0000266_abnormal_heart_morphology | 0.63859781 |
128 | MP0002089_abnormal_postnatal_growth/wei | 0.63664037 |
129 | MP0002429_abnormal_blood_cell | 0.62962483 |
130 | MP0001216_abnormal_epidermal_layer | 0.61530211 |
131 | MP0003121_genomic_imprinting | 0.60969622 |
132 | MP0005275_abnormal_skin_tensile | 0.60685864 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 3.79953515 |
2 | Selective tooth agenesis (HP:0001592) | 3.57894799 |
3 | Insomnia (HP:0100785) | 3.04818761 |
4 | Progressive muscle weakness (HP:0003323) | 2.96097164 |
5 | Multiple enchondromatosis (HP:0005701) | 2.78283862 |
6 | Colon cancer (HP:0003003) | 2.78012774 |
7 | Asymmetry of the thorax (HP:0001555) | 2.77849515 |
8 | Premature rupture of membranes (HP:0001788) | 2.77160195 |
9 | Reticulocytopenia (HP:0001896) | 2.75248185 |
10 | Astrocytoma (HP:0009592) | 2.71817161 |
11 | Abnormality of the astrocytes (HP:0100707) | 2.71817161 |
12 | Ankyloglossia (HP:0010296) | 2.71756146 |
13 | Degeneration of anterior horn cells (HP:0002398) | 2.70687107 |
14 | Abnormality of the anterior horn cell (HP:0006802) | 2.70687107 |
15 | Trismus (HP:0000211) | 2.68647749 |
16 | Basal cell carcinoma (HP:0002671) | 2.68572951 |
17 | Deviation of the thumb (HP:0009603) | 2.66642759 |
18 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.66447361 |
19 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.62881342 |
20 | Distal lower limb amyotrophy (HP:0008944) | 2.62492430 |
21 | Proximal placement of thumb (HP:0009623) | 2.62084393 |
22 | Protrusio acetabuli (HP:0003179) | 2.61949800 |
23 | Hyperacusis (HP:0010780) | 2.55592788 |
24 | Medulloblastoma (HP:0002885) | 2.50969221 |
25 | Ankle contracture (HP:0006466) | 2.48213469 |
26 | Increased density of long bones (HP:0006392) | 2.47011044 |
27 | Hand muscle atrophy (HP:0009130) | 2.46838891 |
28 | Abnormality of the Achilles tendon (HP:0005109) | 2.41469591 |
29 | Abnormality of oral frenula (HP:0000190) | 2.41041504 |
30 | Abnormality of the calcaneus (HP:0008364) | 2.41015570 |
31 | Chromsome breakage (HP:0040012) | 2.40582764 |
32 | Progressive external ophthalmoplegia (HP:0000590) | 2.39148535 |
33 | Abnormal number of erythroid precursors (HP:0012131) | 2.37481005 |
34 | Dysmetric saccades (HP:0000641) | 2.33839754 |
35 | Missing ribs (HP:0000921) | 2.30809411 |
36 | Increased nuchal translucency (HP:0010880) | 2.30760801 |
37 | Cerebral aneurysm (HP:0004944) | 2.30759244 |
38 | Overriding aorta (HP:0002623) | 2.30241537 |
39 | Angiofibromas (HP:0010615) | 2.28786589 |
40 | Adenoma sebaceum (HP:0009720) | 2.28786589 |
41 | Rhabdomyosarcoma (HP:0002859) | 2.27962892 |
42 | Vertebral compression fractures (HP:0002953) | 2.26746622 |
43 | Upper limb amyotrophy (HP:0009129) | 2.26231716 |
44 | Distal upper limb amyotrophy (HP:0007149) | 2.26231716 |
45 | High pitched voice (HP:0001620) | 2.26151851 |
46 | Sparse lateral eyebrow (HP:0005338) | 2.25645712 |
47 | Spastic diplegia (HP:0001264) | 2.23108172 |
48 | Microvesicular hepatic steatosis (HP:0001414) | 2.22462182 |
49 | Ulnar bowing (HP:0003031) | 2.20850009 |
50 | Insidious onset (HP:0003587) | 2.19529385 |
51 | Termporal pattern (HP:0011008) | 2.19529385 |
52 | Elfin facies (HP:0004428) | 2.18066198 |
53 | Short 4th metacarpal (HP:0010044) | 2.17982724 |
54 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.17982724 |
55 | Rectal prolapse (HP:0002035) | 2.15565278 |
56 | Flat acetabular roof (HP:0003180) | 2.15328193 |
57 | Thrombocytosis (HP:0001894) | 2.15206341 |
58 | Biliary tract neoplasm (HP:0100574) | 2.14648031 |
59 | Squamous cell carcinoma (HP:0002860) | 2.13783971 |
60 | Ragged-red muscle fibers (HP:0003200) | 2.13279030 |
61 | Long palpebral fissure (HP:0000637) | 2.12748251 |
62 | Genu recurvatum (HP:0002816) | 2.10959002 |
63 | Birth length less than 3rd percentile (HP:0003561) | 2.09928353 |
64 | Neoplasm of the pancreas (HP:0002894) | 2.09788340 |
65 | Patellar dislocation (HP:0002999) | 2.09329099 |
66 | Abnormal gallbladder physiology (HP:0012438) | 2.09306485 |
67 | Cholecystitis (HP:0001082) | 2.09306485 |
68 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.09182434 |
69 | Short nail (HP:0001799) | 2.08017014 |
70 | Broad face (HP:0000283) | 2.07951475 |
71 | Cutaneous melanoma (HP:0012056) | 2.06072336 |
72 | Neoplasm of striated muscle (HP:0009728) | 2.04685763 |
73 | Disproportionate tall stature (HP:0001519) | 2.04433185 |
74 | Glioma (HP:0009733) | 2.02795899 |
75 | Overlapping toe (HP:0001845) | 2.02672765 |
76 | Reticulocytosis (HP:0001923) | 2.01965630 |
77 | Shallow orbits (HP:0000586) | 2.01303670 |
78 | Carpal bone hypoplasia (HP:0001498) | 2.00791380 |
79 | Pseudobulbar signs (HP:0002200) | 1.99986508 |
80 | Oral leukoplakia (HP:0002745) | 1.98269786 |
81 | Difficulty climbing stairs (HP:0003551) | 1.95487829 |
82 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.95153784 |
83 | Breast hypoplasia (HP:0003187) | 1.94985428 |
84 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.94481296 |
85 | Gastrointestinal carcinoma (HP:0002672) | 1.94481296 |
86 | Prominent nose (HP:0000448) | 1.93436328 |
87 | Osteolytic defects of the hand bones (HP:0009699) | 1.92473475 |
88 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.92473475 |
89 | Absent thumb (HP:0009777) | 1.92462641 |
90 | Increased connective tissue (HP:0009025) | 1.92411788 |
91 | Impulsivity (HP:0100710) | 1.91753539 |
92 | Agnosia (HP:0010524) | 1.91484486 |
93 | Syringomyelia (HP:0003396) | 1.91346192 |
94 | Spinal cord lesions (HP:0100561) | 1.91346192 |
95 | Renal duplication (HP:0000075) | 1.90896458 |
96 | Atresia of the external auditory canal (HP:0000413) | 1.90333236 |
97 | Metaphyseal cupping (HP:0003021) | 1.89240804 |
98 | Advanced eruption of teeth (HP:0006288) | 1.88139031 |
99 | Septate vagina (HP:0001153) | 1.87568055 |
100 | Skin tags (HP:0010609) | 1.85253031 |
101 | Pelvic girdle muscle weakness (HP:0003749) | 1.84074816 |
102 | Patellar aplasia (HP:0006443) | 1.83647776 |
103 | Back pain (HP:0003418) | 1.82370235 |
104 | Broad distal phalanx of finger (HP:0009836) | 1.81427165 |
105 | Deep philtrum (HP:0002002) | 1.81061177 |
106 | Abnormality of the umbilical cord (HP:0010881) | 1.80935093 |
107 | Abnormality of reticulocytes (HP:0004312) | 1.80661288 |
108 | Lower limb amyotrophy (HP:0007210) | 1.80364775 |
109 | 11 pairs of ribs (HP:0000878) | 1.79650287 |
110 | Ulnar deviation of the wrist (HP:0003049) | 1.79587427 |
111 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.79089285 |
112 | Fragile skin (HP:0001030) | 1.79028838 |
113 | Elbow flexion contracture (HP:0002987) | 1.77479377 |
114 | Fibroma (HP:0010614) | 1.77455743 |
115 | Preauricular skin tag (HP:0000384) | 1.76507363 |
116 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.75913199 |
117 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.75587554 |
118 | Achilles tendon contracture (HP:0001771) | 1.75217190 |
119 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.75125310 |
120 | Natal tooth (HP:0000695) | 1.75046452 |
121 | Orthostatic hypotension (HP:0001278) | 1.74801348 |
122 | Facial hemangioma (HP:0000329) | 1.74743312 |
123 | Cafe-au-lait spot (HP:0000957) | 1.74254100 |
124 | Bowel diverticulosis (HP:0005222) | 1.73978004 |
125 | Pointed chin (HP:0000307) | 1.72283733 |
126 | Distal lower limb muscle weakness (HP:0009053) | 1.71742593 |
127 | Micronodular cirrhosis (HP:0001413) | 1.71066610 |
128 | Abnormality of the salivary glands (HP:0010286) | 1.70389707 |
129 | Fibrous tissue neoplasm (HP:0012316) | 1.70122374 |
130 | Abnormality of the thoracic spine (HP:0100711) | 1.70013842 |
131 | Amaurosis fugax (HP:0100576) | 1.69042100 |
132 | Abnormality of the 4th metacarpal (HP:0010012) | 1.68636817 |
133 | Deep palmar crease (HP:0006191) | 1.68372746 |
134 | Cervical subluxation (HP:0003308) | 1.68175850 |
135 | Short humerus (HP:0005792) | 1.67880355 |
136 | Intestinal polyp (HP:0005266) | 1.67859217 |
137 | Slender long bone (HP:0003100) | 1.66976824 |
138 | Urethral obstruction (HP:0000796) | 1.64665374 |
139 | Abnormality of the peritoneum (HP:0002585) | 1.64423103 |
140 | Heterotopia (HP:0002282) | 1.64163130 |
141 | Biconcave vertebral bodies (HP:0004586) | 1.64020100 |
142 | Neoplasm of the oral cavity (HP:0100649) | 1.63734462 |
143 | Radial bowing (HP:0002986) | 1.63694923 |
144 | Abnormality of the lower motor neuron (HP:0002366) | 1.63458259 |
145 | Abnormal number of incisors (HP:0011064) | 1.63187471 |
146 | Flat cornea (HP:0007720) | 1.63082941 |
147 | Renovascular hypertension (HP:0100817) | 1.62816284 |
148 | Entropion (HP:0000621) | 1.62244773 |
149 | Pallor (HP:0000980) | 1.61905906 |
150 | Glossoptosis (HP:0000162) | 1.61839479 |
151 | Macrocytic anemia (HP:0001972) | 1.61833764 |
152 | Broad palm (HP:0001169) | 1.61189921 |
153 | Progressive hearing impairment (HP:0001730) | 1.61052706 |
154 | Ovarian neoplasm (HP:0100615) | 1.60909226 |
155 | Premature skin wrinkling (HP:0100678) | 1.60192650 |
156 | Abnormality of the tricuspid valve (HP:0001702) | 1.59425665 |
157 | Spinal rigidity (HP:0003306) | 1.58987465 |
158 | Subacute progressive viral hepatitis (HP:0006572) | 1.58501099 |
159 | Myelodysplasia (HP:0002863) | 1.58082217 |
160 | Spinal cord compression (HP:0002176) | 1.57767977 |
161 | Spinal muscular atrophy (HP:0007269) | 1.57556957 |
162 | Leiomyosarcoma (HP:0100243) | 1.57373499 |
163 | Uterine leiomyosarcoma (HP:0002891) | 1.57373499 |
164 | Arnold-Chiari malformation (HP:0002308) | 1.56958996 |
165 | Relative macrocephaly (HP:0004482) | 1.54604285 |
166 | Bladder diverticulum (HP:0000015) | 1.53890185 |
167 | Ridged nail (HP:0001807) | 1.53865056 |
168 | Generalized amyotrophy (HP:0003700) | 1.52330924 |
169 | Pili torti (HP:0003777) | 1.52062510 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 3.95259475 |
2 | EEF2K | 3.84259010 |
3 | TRIB3 | 3.48912829 |
4 | PKN2 | 3.38763341 |
5 | CDC7 | 3.34829083 |
6 | CDK12 | 3.13909201 |
7 | IRAK3 | 2.90591319 |
8 | NEK2 | 2.61492542 |
9 | MAP3K10 | 2.52424954 |
10 | WEE1 | 2.51061703 |
11 | PRPF4B | 2.18903183 |
12 | BUB1 | 2.10928198 |
13 | MST1R | 2.05822250 |
14 | SCYL2 | 1.94030269 |
15 | RPS6KB2 | 1.87675641 |
16 | PASK | 1.78819125 |
17 | NEK1 | 1.76851172 |
18 | EPHA2 | 1.72533619 |
19 | TTK | 1.70563561 |
20 | TSSK6 | 1.67278878 |
21 | PBK | 1.58867724 |
22 | STK10 | 1.58437783 |
23 | TTN | 1.57603069 |
24 | CDK4 | 1.57471685 |
25 | NME2 | 1.56156945 |
26 | RPS6KA4 | 1.54911458 |
27 | PAK4 | 1.49739048 |
28 | MAP3K8 | 1.49504487 |
29 | LRRK2 | 1.48703421 |
30 | ALK | 1.43157172 |
31 | CDK7 | 1.42090429 |
32 | TESK2 | 1.36257263 |
33 | ICK | 1.33432453 |
34 | TESK1 | 1.33087463 |
35 | PTK6 | 1.32164975 |
36 | ERN1 | 1.31630164 |
37 | MAP4K1 | 1.31407131 |
38 | EIF2AK1 | 1.29227663 |
39 | MAP2K3 | 1.26394074 |
40 | TGFBR1 | 1.20421776 |
41 | FLT3 | 1.18719186 |
42 | MTOR | 1.18002963 |
43 | PLK1 | 1.17023681 |
44 | AURKB | 1.14329392 |
45 | ATR | 1.09596434 |
46 | CDK6 | 1.07892905 |
47 | CHEK1 | 1.06417725 |
48 | PAK2 | 1.01809612 |
49 | BRSK2 | 1.01171509 |
50 | PDGFRA | 0.97148822 |
51 | KSR2 | 0.96385840 |
52 | DYRK3 | 0.94757244 |
53 | BMX | 0.93913935 |
54 | TAOK2 | 0.93021113 |
55 | BRD4 | 0.92780268 |
56 | RIPK1 | 0.90847337 |
57 | MAP3K11 | 0.89042900 |
58 | STK3 | 0.87254084 |
59 | PIM1 | 0.85903024 |
60 | PDK3 | 0.84888596 |
61 | PDK4 | 0.84888596 |
62 | CDK8 | 0.82984361 |
63 | LATS1 | 0.82339355 |
64 | AURKA | 0.81559609 |
65 | CHEK2 | 0.81109404 |
66 | SRPK1 | 0.79536721 |
67 | ZAP70 | 0.77269317 |
68 | BRAF | 0.77118352 |
69 | GRK6 | 0.75523543 |
70 | MAPK11 | 0.74818224 |
71 | MKNK1 | 0.74203247 |
72 | * CDK2 | 0.73295902 |
73 | CLK1 | 0.71948037 |
74 | ARAF | 0.71167834 |
75 | ERBB4 | 0.70327295 |
76 | MAPKAPK3 | 0.69862327 |
77 | MAP3K3 | 0.69309935 |
78 | MAP2K2 | 0.67735990 |
79 | MAP3K9 | 0.66605878 |
80 | MAP3K13 | 0.66583037 |
81 | KDR | 0.66550849 |
82 | PAK1 | 0.65851225 |
83 | ATM | 0.65047939 |
84 | ACVR1B | 0.63680757 |
85 | ILK | 0.63609489 |
86 | VRK2 | 0.63199733 |
87 | STK4 | 0.62249711 |
88 | LATS2 | 0.61747630 |
89 | PLK3 | 0.58297291 |
90 | SIK1 | 0.56793490 |
91 | LMTK2 | 0.55816481 |
92 | AKT2 | 0.55743617 |
93 | EIF2AK3 | 0.55742116 |
94 | JAK3 | 0.55255539 |
95 | CDK9 | 0.54717000 |
96 | TAOK1 | 0.54630043 |
97 | TAF1 | 0.54549606 |
98 | IRAK2 | 0.54253243 |
99 | PIM2 | 0.53011549 |
100 | FGFR1 | 0.52860738 |
101 | RAF1 | 0.52534334 |
102 | CSNK2A2 | 0.51396658 |
103 | BCKDK | 0.48165937 |
104 | MET | 0.47580047 |
105 | BRSK1 | 0.47338798 |
106 | MAP3K14 | 0.45957056 |
107 | NTRK1 | 0.45794947 |
108 | CAMK1G | 0.42533439 |
109 | CDK1 | 0.42499343 |
110 | PTK2 | 0.42449396 |
111 | TLK1 | 0.42327115 |
112 | RPS6KA1 | 0.41583163 |
113 | BTK | 0.40506448 |
114 | MAP3K1 | 0.40492180 |
115 | PDPK1 | 0.39896019 |
116 | TYRO3 | 0.39666809 |
117 | PRKD3 | 0.38463864 |
118 | * CSNK1E | 0.36891751 |
119 | PNCK | 0.36859796 |
120 | MELK | 0.36002081 |
121 | CAMK1D | 0.33614704 |
122 | DDR2 | 0.33289654 |
123 | PRKCI | 0.33159343 |
124 | PRKDC | 0.32865781 |
125 | FGFR4 | 0.32446987 |
126 | DMPK | 0.31493028 |
127 | PDGFRB | 0.30945790 |
128 | RET | 0.30399461 |
129 | RPS6KB1 | 0.27697688 |
130 | EIF2AK2 | 0.27249222 |
131 | RPS6KL1 | 0.26612769 |
132 | RPS6KC1 | 0.26612769 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.17123392 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.27695875 |
3 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.17267197 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.08159233 |
5 | * RNA transport_Homo sapiens_hsa03013 | 3.07753181 |
6 | Spliceosome_Homo sapiens_hsa03040 | 2.89564146 |
7 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.65186689 |
8 | Cell cycle_Homo sapiens_hsa04110 | 2.39137739 |
9 | Base excision repair_Homo sapiens_hsa03410 | 2.33435054 |
10 | Ribosome_Homo sapiens_hsa03010 | 2.32460468 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.07879939 |
12 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.90265873 |
13 | Homologous recombination_Homo sapiens_hsa03440 | 1.71255089 |
14 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.58245505 |
15 | Proteasome_Homo sapiens_hsa03050 | 1.56025627 |
16 | RNA polymerase_Homo sapiens_hsa03020 | 1.55953213 |
17 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.49644042 |
18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.48376859 |
19 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.40702332 |
20 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.31630390 |
21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.31432275 |
22 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.27501057 |
23 | RNA degradation_Homo sapiens_hsa03018 | 1.25864285 |
24 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.25685227 |
25 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.23235675 |
26 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.17351881 |
27 | Other glycan degradation_Homo sapiens_hsa00511 | 1.15956284 |
28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.11734891 |
29 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.10834067 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.10366297 |
31 | Thyroid cancer_Homo sapiens_hsa05216 | 1.10085241 |
32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.09826181 |
33 | Bladder cancer_Homo sapiens_hsa05219 | 1.08495567 |
34 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.08313874 |
35 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.07834637 |
36 | Sulfur relay system_Homo sapiens_hsa04122 | 1.07569422 |
37 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05554380 |
38 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.04294505 |
39 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.03999304 |
40 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.03754761 |
41 | Prion diseases_Homo sapiens_hsa05020 | 1.02085429 |
42 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.01915230 |
43 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.01471792 |
44 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.00188159 |
45 | Glioma_Homo sapiens_hsa05214 | 0.99593971 |
46 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.96340094 |
47 | Carbon metabolism_Homo sapiens_hsa01200 | 0.96073782 |
48 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.92815629 |
49 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.91249534 |
50 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.90871296 |
51 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.87901049 |
52 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.87479061 |
53 | Legionellosis_Homo sapiens_hsa05134 | 0.86478425 |
54 | Basal transcription factors_Homo sapiens_hsa03022 | 0.85875108 |
55 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.85654768 |
56 | Lysine degradation_Homo sapiens_hsa00310 | 0.84686460 |
57 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.84169249 |
58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.84148845 |
59 | Adherens junction_Homo sapiens_hsa04520 | 0.80870645 |
60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.79347752 |
61 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.78745663 |
62 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75311908 |
63 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.75268445 |
64 | Apoptosis_Homo sapiens_hsa04210 | 0.73895745 |
65 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.71984441 |
66 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.71575187 |
67 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.71439108 |
68 | Viral myocarditis_Homo sapiens_hsa05416 | 0.71128946 |
69 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.69146230 |
70 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.67637657 |
71 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67358532 |
72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.67024543 |
73 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.66319806 |
74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.65386367 |
75 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.64059623 |
76 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.64014780 |
77 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.63442783 |
78 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61741472 |
79 | Shigellosis_Homo sapiens_hsa05131 | 0.61049629 |
80 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.60595324 |
81 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.57628242 |
82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.57594157 |
83 | Melanoma_Homo sapiens_hsa05218 | 0.56320609 |
84 | Hepatitis C_Homo sapiens_hsa05160 | 0.55615624 |
85 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.54876898 |
86 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.54560217 |
87 | Focal adhesion_Homo sapiens_hsa04510 | 0.54553369 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.53683375 |
89 | Hepatitis B_Homo sapiens_hsa05161 | 0.53281844 |
90 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.50827737 |
91 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.50216436 |
92 | Endometrial cancer_Homo sapiens_hsa05213 | 0.50192455 |
93 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.49794003 |
94 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49743317 |
95 | Purine metabolism_Homo sapiens_hsa00230 | 0.49001107 |
96 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.48770078 |
97 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.48614083 |
98 | Prostate cancer_Homo sapiens_hsa05215 | 0.48168380 |
99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.48158138 |
100 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.47675616 |
101 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47610321 |
102 | Alcoholism_Homo sapiens_hsa05034 | 0.46758048 |
103 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.46383535 |
104 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.44875648 |
105 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.44241946 |
106 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.43569365 |
107 | Pathways in cancer_Homo sapiens_hsa05200 | 0.43515696 |
108 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.43340527 |
109 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.43184666 |
110 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.42921262 |
111 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.42810988 |
112 | Measles_Homo sapiens_hsa05162 | 0.41700772 |
113 | Galactose metabolism_Homo sapiens_hsa00052 | 0.40952230 |
114 | Tight junction_Homo sapiens_hsa04530 | 0.40387201 |
115 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.39704700 |
116 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.39603559 |
117 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.38100262 |
118 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.36985624 |
119 | Insulin resistance_Homo sapiens_hsa04931 | 0.36348368 |
120 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.35648649 |
121 | Influenza A_Homo sapiens_hsa05164 | 0.34029290 |