| 1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.22278403 |
| 2 | Abnormal number of erythroid precursors (HP:0012131) | 4.87103634 |
| 3 | Reticulocytopenia (HP:0001896) | 4.80612284 |
| 4 | Birth length less than 3rd percentile (HP:0003561) | 3.82781701 |
| 5 | Colon cancer (HP:0003003) | 3.70379764 |
| 6 | Thrombocytosis (HP:0001894) | 3.58394209 |
| 7 | Aplastic anemia (HP:0001915) | 3.46047975 |
| 8 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.37187306 |
| 9 | Embryonal renal neoplasm (HP:0011794) | 3.21491987 |
| 10 | 11 pairs of ribs (HP:0000878) | 3.20407189 |
| 11 | Pallor (HP:0000980) | 3.13821738 |
| 12 | Abnormality of methionine metabolism (HP:0010901) | 3.11661500 |
| 13 | Macrocytic anemia (HP:0001972) | 3.05842737 |
| 14 | Abnormality of the anterior horn cell (HP:0006802) | 2.99856541 |
| 15 | Degeneration of anterior horn cells (HP:0002398) | 2.99856541 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97506532 |
| 17 | Microvesicular hepatic steatosis (HP:0001414) | 2.75850374 |
| 18 | Rhabdomyosarcoma (HP:0002859) | 2.69546901 |
| 19 | Selective tooth agenesis (HP:0001592) | 2.67093974 |
| 20 | Oral leukoplakia (HP:0002745) | 2.66901025 |
| 21 | Myelodysplasia (HP:0002863) | 2.56305027 |
| 22 | IgM deficiency (HP:0002850) | 2.53376647 |
| 23 | Breast hypoplasia (HP:0003187) | 2.49244505 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.43836958 |
| 25 | Triphalangeal thumb (HP:0001199) | 2.42704765 |
| 26 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.42398839 |
| 27 | Megaloblastic anemia (HP:0001889) | 2.38523102 |
| 28 | Abnormality of chromosome stability (HP:0003220) | 2.34794795 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.31812963 |
| 30 | Acute lymphatic leukemia (HP:0006721) | 2.29049067 |
| 31 | Medulloblastoma (HP:0002885) | 2.28187075 |
| 32 | Absent thumb (HP:0009777) | 2.27527298 |
| 33 | Abnormality of the duodenum (HP:0002246) | 2.24901294 |
| 34 | Agnosia (HP:0010524) | 2.23955606 |
| 35 | Chromsome breakage (HP:0040012) | 2.23296171 |
| 36 | Rough bone trabeculation (HP:0100670) | 2.22923078 |
| 37 | Amaurosis fugax (HP:0100576) | 2.21874857 |
| 38 | Lymphoma (HP:0002665) | 2.21696465 |
| 39 | Glossoptosis (HP:0000162) | 2.21505052 |
| 40 | Abnormality of the calcaneus (HP:0008364) | 2.20218465 |
| 41 | Trismus (HP:0000211) | 2.19276443 |
| 42 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.18513397 |
| 43 | Patellar aplasia (HP:0006443) | 2.15195490 |
| 44 | Reduced antithrombin III activity (HP:0001976) | 2.13874300 |
| 45 | Multiple enchondromatosis (HP:0005701) | 2.13854274 |
| 46 | Basal cell carcinoma (HP:0002671) | 2.12768091 |
| 47 | Abnormality of glycolysis (HP:0004366) | 2.12472384 |
| 48 | Premature graying of hair (HP:0002216) | 2.11509069 |
| 49 | Cutaneous melanoma (HP:0012056) | 2.10920752 |
| 50 | Meckel diverticulum (HP:0002245) | 2.10006771 |
| 51 | Increased serum pyruvate (HP:0003542) | 2.09178667 |
| 52 | Abnormality of the preputium (HP:0100587) | 2.09081170 |
| 53 | Carpal bone hypoplasia (HP:0001498) | 2.04455845 |
| 54 | Increased nuchal translucency (HP:0010880) | 2.04452327 |
| 55 | Muscle fiber atrophy (HP:0100295) | 2.04008332 |
| 56 | Neoplasm of the pancreas (HP:0002894) | 2.03988637 |
| 57 | Spinal cord lesions (HP:0100561) | 2.01817590 |
| 58 | Syringomyelia (HP:0003396) | 2.01817590 |
| 59 | Optic nerve coloboma (HP:0000588) | 2.01532296 |
| 60 | Abnormality of T cell number (HP:0011839) | 2.01263475 |
| 61 | IgG deficiency (HP:0004315) | 2.01157152 |
| 62 | Abnormality of serum amino acid levels (HP:0003112) | 2.01062600 |
| 63 | Biliary tract neoplasm (HP:0100574) | 2.00957324 |
| 64 | Dyschromatopsia (HP:0007641) | 2.00087192 |
| 65 | T lymphocytopenia (HP:0005403) | 1.99434216 |
| 66 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.99343791 |
| 67 | Breast carcinoma (HP:0003002) | 1.98010930 |
| 68 | Irregular epiphyses (HP:0010582) | 1.97716649 |
| 69 | Ependymoma (HP:0002888) | 1.96804484 |
| 70 | Abnormality of the ileum (HP:0001549) | 1.96693503 |
| 71 | Abnormality of T cells (HP:0002843) | 1.95958874 |
| 72 | Abnormality of homocysteine metabolism (HP:0010919) | 1.95915795 |
| 73 | Homocystinuria (HP:0002156) | 1.95915795 |
| 74 | Ovarian neoplasm (HP:0100615) | 1.95846391 |
| 75 | Type 2 muscle fiber atrophy (HP:0003554) | 1.95647756 |
| 76 | Microretrognathia (HP:0000308) | 1.94864737 |
| 77 | Abnormal lung lobation (HP:0002101) | 1.92937805 |
| 78 | Atresia of the external auditory canal (HP:0000413) | 1.92349364 |
| 79 | Central scotoma (HP:0000603) | 1.90918654 |
| 80 | Abnormality of DNA repair (HP:0003254) | 1.90454034 |
| 81 | Calcaneovalgus deformity (HP:0001848) | 1.89264558 |
| 82 | Microglossia (HP:0000171) | 1.88543105 |
| 83 | Small intestinal stenosis (HP:0012848) | 1.87754883 |
| 84 | Duodenal stenosis (HP:0100867) | 1.87754883 |
| 85 | Neoplasm of the colon (HP:0100273) | 1.87589174 |
| 86 | Squamous cell carcinoma (HP:0002860) | 1.87324208 |
| 87 | Congenital, generalized hypertrichosis (HP:0004540) | 1.87063273 |
| 88 | Acute myeloid leukemia (HP:0004808) | 1.86885169 |
| 89 | Entropion (HP:0000621) | 1.86295106 |
| 90 | Bone marrow hypocellularity (HP:0005528) | 1.85597447 |
| 91 | Abnormality of B cell number (HP:0010975) | 1.85419851 |
| 92 | B lymphocytopenia (HP:0010976) | 1.85419851 |
| 93 | Recurrent bronchitis (HP:0002837) | 1.84368722 |
| 94 | Missing ribs (HP:0000921) | 1.83316217 |
| 95 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.83111845 |
| 96 | Deviation of the thumb (HP:0009603) | 1.82603569 |
| 97 | Neoplasm of the small intestine (HP:0100833) | 1.81617918 |
| 98 | Hypoplastic pelvis (HP:0008839) | 1.81564536 |
| 99 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.79985674 |
| 100 | Progressive external ophthalmoplegia (HP:0000590) | 1.79461421 |
| 101 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.79381246 |
| 102 | Methylmalonic acidemia (HP:0002912) | 1.79264708 |
| 103 | Posterior subcapsular cataract (HP:0007787) | 1.78685221 |
| 104 | Choanal atresia (HP:0000453) | 1.78649313 |
| 105 | Respiratory difficulties (HP:0002880) | 1.78225045 |
| 106 | Uterine neoplasm (HP:0010784) | 1.77652648 |
| 107 | Deep philtrum (HP:0002002) | 1.77194774 |
| 108 | Poor head control (HP:0002421) | 1.76779676 |
| 109 | Type I transferrin isoform profile (HP:0003642) | 1.76421989 |
| 110 | Proximal placement of thumb (HP:0009623) | 1.76277405 |
| 111 | Cafe-au-lait spot (HP:0000957) | 1.76054198 |
| 112 | Embryonal neoplasm (HP:0002898) | 1.75771524 |
| 113 | Abnormality of T cell physiology (HP:0011840) | 1.75733940 |
| 114 | Abnormal number of incisors (HP:0011064) | 1.75669550 |
| 115 | Bifid tongue (HP:0010297) | 1.75262560 |
| 116 | Horseshoe kidney (HP:0000085) | 1.75252250 |
| 117 | Poikiloderma (HP:0001029) | 1.74944234 |
| 118 | Gonadotropin excess (HP:0000837) | 1.74871207 |
| 119 | Stenosis of the external auditory canal (HP:0000402) | 1.74099581 |
| 120 | Cellular immunodeficiency (HP:0005374) | 1.73933552 |
| 121 | Increased density of long bones (HP:0006392) | 1.73927782 |
| 122 | Neoplasm of the adrenal cortex (HP:0100641) | 1.73032703 |
| 123 | Clubbing of toes (HP:0100760) | 1.72326500 |
| 124 | Neoplasm of the adrenal gland (HP:0100631) | 1.71842097 |
| 125 | Volvulus (HP:0002580) | 1.71558905 |
| 126 | Deformed tarsal bones (HP:0008119) | 1.71390886 |
| 127 | Short middle phalanx of the 5th finger (HP:0004220) | 1.70893843 |
| 128 | Cystic hygroma (HP:0000476) | 1.70350672 |
| 129 | Papillary thyroid carcinoma (HP:0002895) | 1.69554363 |
| 130 | Sloping forehead (HP:0000340) | 1.69443583 |
| 131 | Petechiae (HP:0000967) | 1.69183722 |
| 132 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.68715346 |
| 133 | Postnatal microcephaly (HP:0005484) | 1.67539499 |
| 134 | Thyroid carcinoma (HP:0002890) | 1.66188025 |
| 135 | Arteriovenous malformation (HP:0100026) | 1.65945106 |
| 136 | Pancytopenia (HP:0001876) | 1.65842899 |
| 137 | Depressed nasal ridge (HP:0000457) | 1.65031825 |
| 138 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.64644030 |
| 139 | Glioma (HP:0009733) | 1.64502168 |
| 140 | Cleft eyelid (HP:0000625) | 1.63957973 |
| 141 | Acute encephalopathy (HP:0006846) | 1.63696341 |
| 142 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.63369309 |
| 143 | Abnormal trabecular bone morphology (HP:0100671) | 1.63155608 |
| 144 | Asymmetry of the thorax (HP:0001555) | 1.62811117 |
| 145 | Hypoglycemic seizures (HP:0002173) | 1.62586652 |
| 146 | Hyperglycinemia (HP:0002154) | 1.62260006 |
| 147 | Recurrent viral infections (HP:0004429) | 1.62232823 |
| 148 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.61897945 |
| 149 | Asplenia (HP:0001746) | 1.61840751 |
| 150 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.61777979 |
| 151 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.61105796 |
| 152 | Cervical subluxation (HP:0003308) | 1.60592525 |
| 153 | Slender long bone (HP:0003100) | 1.60493483 |
| 154 | Absent radius (HP:0003974) | 1.59800152 |
| 155 | Increased CSF lactate (HP:0002490) | 1.59667035 |
| 156 | Increased serum lactate (HP:0002151) | 1.59657611 |
| 157 | Facial hemangioma (HP:0000329) | 1.59501746 |
| 158 | Adenoma sebaceum (HP:0009720) | 1.59023309 |
| 159 | Angiofibromas (HP:0010615) | 1.59023309 |
| 160 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.58974654 |
| 161 | Hypoglycemic coma (HP:0001325) | 1.58460409 |
| 162 | Curly hair (HP:0002212) | 1.58192697 |
| 163 | Abnormality of reticulocytes (HP:0004312) | 1.56244898 |
| 164 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.55798374 |
| 165 | Combined immunodeficiency (HP:0005387) | 1.55163833 |
| 166 | Facial cleft (HP:0002006) | 1.54904996 |
| 167 | Protrusio acetabuli (HP:0003179) | 1.54666799 |
| 168 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.53726694 |
EIF3E 
