

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.12380697 |
| 2 | proteasome assembly (GO:0043248) | 4.65215640 |
| 3 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 4.05407725 |
| 4 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 4.01713225 |
| 5 | cullin deneddylation (GO:0010388) | 4.00340745 |
| 6 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 3.86754259 |
| 7 | piRNA metabolic process (GO:0034587) | 3.84898864 |
| 8 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.81338198 |
| 9 | maturation of 5.8S rRNA (GO:0000460) | 3.77634829 |
| 10 | protein deneddylation (GO:0000338) | 3.74518098 |
| 11 | platelet dense granule organization (GO:0060155) | 3.71025671 |
| 12 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.69859790 |
| 13 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.59990357 |
| 14 | cytidine deamination (GO:0009972) | 3.53791391 |
| 15 | cytidine metabolic process (GO:0046087) | 3.53791391 |
| 16 | cytidine catabolic process (GO:0006216) | 3.53791391 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.52288188 |
| 18 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.48022702 |
| 19 | positive regulation of protein homodimerization activity (GO:0090073) | 3.40908655 |
| 20 | rRNA modification (GO:0000154) | 3.40179228 |
| 21 | formation of translation preinitiation complex (GO:0001731) | 3.36805452 |
| 22 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.34703663 |
| 23 | synapsis (GO:0007129) | 3.34455539 |
| 24 | skeletal muscle tissue regeneration (GO:0043403) | 3.29011374 |
| 25 | response to gravity (GO:0009629) | 3.24093325 |
| 26 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.19008666 |
| 27 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.17696499 |
| 28 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.12513276 |
| 29 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.12486848 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.12486848 |
| 31 | DNA double-strand break processing (GO:0000729) | 3.10402894 |
| 32 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.09856091 |
| 33 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.09686924 |
| 34 | termination of RNA polymerase I transcription (GO:0006363) | 3.08522638 |
| 35 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.07568690 |
| 36 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.07568690 |
| 37 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.07568690 |
| 38 | ribosomal small subunit assembly (GO:0000028) | 3.07045483 |
| 39 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.06656945 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.06656945 |
| 41 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.04890356 |
| 42 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.03974982 |
| 43 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.03974982 |
| 44 | protein neddylation (GO:0045116) | 3.03328403 |
| 45 | male meiosis (GO:0007140) | 3.02310053 |
| 46 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.94060469 |
| 47 | lactate metabolic process (GO:0006089) | 2.93646383 |
| 48 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.92283472 |
| 49 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.89789222 |
| 50 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.89789222 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.89727919 |
| 52 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.89697728 |
| 53 | serotonin receptor signaling pathway (GO:0007210) | 2.88314501 |
| 54 | CENP-A containing nucleosome assembly (GO:0034080) | 2.86954606 |
| 55 | chromatin remodeling at centromere (GO:0031055) | 2.82582914 |
| 56 | protein complex biogenesis (GO:0070271) | 2.82044701 |
| 57 | regulation of centriole replication (GO:0046599) | 2.81992181 |
| 58 | DNA methylation involved in gamete generation (GO:0043046) | 2.81771725 |
| 59 | rRNA methylation (GO:0031167) | 2.80205719 |
| 60 | histone exchange (GO:0043486) | 2.77400353 |
| 61 | aggressive behavior (GO:0002118) | 2.75977929 |
| 62 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.75736623 |
| 63 | termination of RNA polymerase III transcription (GO:0006386) | 2.75736623 |
| 64 | regulation of DNA endoreduplication (GO:0032875) | 2.75620764 |
| 65 | neural tube formation (GO:0001841) | 2.75212157 |
| 66 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.74581532 |
| 67 | male meiosis I (GO:0007141) | 2.72211723 |
| 68 | positive regulation of ligase activity (GO:0051351) | 2.71832293 |
| 69 | organelle disassembly (GO:1903008) | 2.68904356 |
| 70 | ribosomal large subunit biogenesis (GO:0042273) | 2.68287170 |
| 71 | chaperone-mediated protein transport (GO:0072321) | 2.68093003 |
| 72 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.66610269 |
| 73 | rRNA processing (GO:0006364) | 2.66187132 |
| 74 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.64983710 |
| 75 | pseudouridine synthesis (GO:0001522) | 2.64536176 |
| 76 | RNA phosphodiester bond hydrolysis (GO:0090501) | 2.63393215 |
| 77 | indole-containing compound catabolic process (GO:0042436) | 2.63096716 |
| 78 | indolalkylamine catabolic process (GO:0046218) | 2.63096716 |
| 79 | tryptophan catabolic process (GO:0006569) | 2.63096716 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.62718251 |
| 81 | response to pheromone (GO:0019236) | 2.61197426 |
| 82 | keratinocyte development (GO:0003334) | 2.61181858 |
| 83 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.60689282 |
| 84 | respiratory chain complex IV assembly (GO:0008535) | 2.60189889 |
| 85 | reciprocal DNA recombination (GO:0035825) | 2.59909610 |
| 86 | reciprocal meiotic recombination (GO:0007131) | 2.59909610 |
| 87 | protein K6-linked ubiquitination (GO:0085020) | 2.59674784 |
| 88 | rRNA metabolic process (GO:0016072) | 2.59213636 |
| 89 | regulation of meiosis I (GO:0060631) | 2.58297833 |
| 90 | tryptophan metabolic process (GO:0006568) | 2.57015344 |
| 91 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.55940468 |
| 92 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.55940468 |
| 93 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.55902506 |
| 94 | ribonucleoprotein complex disassembly (GO:0032988) | 2.55265840 |
| 95 | maturation of SSU-rRNA (GO:0030490) | 2.55117255 |
| 96 | kynurenine metabolic process (GO:0070189) | 2.54693706 |
| 97 | DNA damage response, detection of DNA damage (GO:0042769) | 2.54653321 |
| 98 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.54410030 |
| 99 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.53916811 |
| 100 | chromosome organization involved in meiosis (GO:0070192) | 2.52999866 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.88325817 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.80644257 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.36842328 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.27656897 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.07441771 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.78439101 |
| 7 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.57473198 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.56262356 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.48148164 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.42973405 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.41655984 |
| 12 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.38882574 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38733670 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.36923732 |
| 15 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.35172860 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.33046217 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.31303919 |
| 18 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.22706700 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.17989659 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.17319761 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 2.15235935 |
| 22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.13830103 |
| 23 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.04271243 |
| 24 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.98885637 |
| 25 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.97394328 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.90966218 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.90171400 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.89240959 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.87600332 |
| 30 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.81012800 |
| 31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.66984157 |
| 32 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.65940730 |
| 33 | P300_19829295_ChIP-Seq_ESCs_Human | 1.65401926 |
| 34 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.65305298 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.62006388 |
| 36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58826708 |
| 37 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.57818141 |
| 38 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.56016608 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.55869663 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.54996533 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51885380 |
| 42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.48925030 |
| 43 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.47803437 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.46745041 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.45203195 |
| 46 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.41438420 |
| 47 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.39958728 |
| 48 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.37631766 |
| 49 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.37539612 |
| 50 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.36116258 |
| 51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.33660858 |
| 52 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.33264236 |
| 53 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31748508 |
| 54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.30180651 |
| 55 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27472968 |
| 56 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.25574241 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.23506888 |
| 58 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.23399470 |
| 59 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.22929850 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21645555 |
| 61 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.21317098 |
| 62 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.20898892 |
| 63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.18314529 |
| 64 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.18314529 |
| 65 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.18284616 |
| 66 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17717290 |
| 67 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.15145280 |
| 68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.14640686 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14210964 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14210964 |
| 71 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13829221 |
| 72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.12182943 |
| 73 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.09850939 |
| 74 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.08978775 |
| 75 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.08815691 |
| 76 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08102192 |
| 77 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.06480768 |
| 78 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06131663 |
| 79 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05441367 |
| 80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.05214435 |
| 81 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.04549443 |
| 82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04267761 |
| 83 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.02486686 |
| 84 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.01112176 |
| 85 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.01034734 |
| 86 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.00197584 |
| 87 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.99506456 |
| 88 | STAT3_23295773_ChIP-Seq_U87_Human | 0.98017124 |
| 89 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.96115468 |
| 90 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95095090 |
| 91 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.94969985 |
| 92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94734818 |
| 93 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.94591628 |
| 94 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.94573871 |
| 95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.92923063 |
| 96 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92012645 |
| 97 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91022316 |
| 98 | AR_25329375_ChIP-Seq_VCAP_Human | 0.90129972 |
| 99 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.89217294 |
| 100 | GATA3_26560356_Chip-Seq_TH2_Human | 0.88906506 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 3.53738511 |
| 2 | MP0008057_abnormal_DNA_replication | 2.73293569 |
| 3 | MP0002102_abnormal_ear_morphology | 2.70177306 |
| 4 | MP0000372_irregular_coat_pigmentation | 2.66983171 |
| 5 | MP0008995_early_reproductive_senescence | 2.59307157 |
| 6 | MP0003786_premature_aging | 2.53745030 |
| 7 | MP0010094_abnormal_chromosome_stability | 2.52466835 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.52168521 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.48030629 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.42099625 |
| 11 | MP0004147_increased_porphyrin_level | 2.41121885 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.36250611 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 2.27996813 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 2.23413629 |
| 15 | MP0000427_abnormal_hair_cycle | 2.04636521 |
| 16 | MP0003567_abnormal_fetal_cardiomyocyte | 1.89829115 |
| 17 | MP0005075_abnormal_melanosome_morpholog | 1.87089025 |
| 18 | MP0006036_abnormal_mitochondrial_physio | 1.78006894 |
| 19 | MP0002095_abnormal_skin_pigmentation | 1.64882275 |
| 20 | MP0005253_abnormal_eye_physiology | 1.64404213 |
| 21 | MP0001529_abnormal_vocalization | 1.61023200 |
| 22 | MP0009697_abnormal_copulation | 1.55147644 |
| 23 | MP0003950_abnormal_plasma_membrane | 1.54276853 |
| 24 | MP0005084_abnormal_gallbladder_morpholo | 1.53359597 |
| 25 | MP0001986_abnormal_taste_sensitivity | 1.52494584 |
| 26 | MP0006035_abnormal_mitochondrial_morpho | 1.48899502 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.48470068 |
| 28 | MP0002736_abnormal_nociception_after | 1.47253013 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.46740776 |
| 30 | MP0002006_tumorigenesis | 1.45144901 |
| 31 | MP0003195_calcinosis | 1.43888604 |
| 32 | MP0002166_altered_tumor_susceptibility | 1.41995668 |
| 33 | MP0004043_abnormal_pH_regulation | 1.39873971 |
| 34 | MP0005646_abnormal_pituitary_gland | 1.39582807 |
| 35 | MP0003880_abnormal_central_pattern | 1.39222042 |
| 36 | MP0005394_taste/olfaction_phenotype | 1.36254703 |
| 37 | MP0005499_abnormal_olfactory_system | 1.36254703 |
| 38 | MP0002210_abnormal_sex_determination | 1.31503957 |
| 39 | MP0002233_abnormal_nose_morphology | 1.30185763 |
| 40 | MP0003718_maternal_effect | 1.27317576 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.26280026 |
| 42 | MP0002277_abnormal_respiratory_mucosa | 1.24958572 |
| 43 | MP0001486_abnormal_startle_reflex | 1.24244084 |
| 44 | MP0009046_muscle_twitch | 1.23779099 |
| 45 | MP0003937_abnormal_limbs/digits/tail_de | 1.20839789 |
| 46 | MP0004145_abnormal_muscle_electrophysio | 1.20455392 |
| 47 | MP0004957_abnormal_blastocyst_morpholog | 1.20065524 |
| 48 | MP0001984_abnormal_olfaction | 1.19378351 |
| 49 | MP0009379_abnormal_foot_pigmentation | 1.18867901 |
| 50 | MP0001873_stomach_inflammation | 1.18624428 |
| 51 | MP0003077_abnormal_cell_cycle | 1.18144697 |
| 52 | MP0002876_abnormal_thyroid_physiology | 1.17725822 |
| 53 | MP0003111_abnormal_nucleus_morphology | 1.17339252 |
| 54 | MP0001929_abnormal_gametogenesis | 1.17094154 |
| 55 | MP0002160_abnormal_reproductive_system | 1.15748871 |
| 56 | MP0003787_abnormal_imprinting | 1.15027928 |
| 57 | MP0001835_abnormal_antigen_presentation | 1.14130480 |
| 58 | MP0001188_hyperpigmentation | 1.13825812 |
| 59 | MP0005171_absent_coat_pigmentation | 1.13195772 |
| 60 | MP0004142_abnormal_muscle_tone | 1.12288178 |
| 61 | MP0001119_abnormal_female_reproductive | 1.12247944 |
| 62 | MP0000383_abnormal_hair_follicle | 1.12148821 |
| 63 | MP0000631_abnormal_neuroendocrine_gland | 1.12121115 |
| 64 | MP0000653_abnormal_sex_gland | 1.12101074 |
| 65 | MP0001905_abnormal_dopamine_level | 1.11930338 |
| 66 | MP0002751_abnormal_autonomic_nervous | 1.11043798 |
| 67 | MP0008872_abnormal_physiological_respon | 1.08099581 |
| 68 | MP0002928_abnormal_bile_duct | 1.05258993 |
| 69 | MP0004036_abnormal_muscle_relaxation | 1.04739296 |
| 70 | MP0003646_muscle_fatigue | 1.03358490 |
| 71 | MP0008007_abnormal_cellular_replicative | 1.02968329 |
| 72 | MP0001293_anophthalmia | 1.01601702 |
| 73 | MP0002396_abnormal_hematopoietic_system | 1.01212889 |
| 74 | MP0000516_abnormal_urinary_system | 1.00873564 |
| 75 | MP0005367_renal/urinary_system_phenotyp | 1.00873564 |
| 76 | MP0005220_abnormal_exocrine_pancreas | 1.00233072 |
| 77 | MP0008775_abnormal_heart_ventricle | 0.97938658 |
| 78 | MP0005671_abnormal_response_to | 0.97363878 |
| 79 | MP0001145_abnormal_male_reproductive | 0.95883292 |
| 80 | MP0005645_abnormal_hypothalamus_physiol | 0.95789031 |
| 81 | MP0004215_abnormal_myocardial_fiber | 0.92362836 |
| 82 | MP0009745_abnormal_behavioral_response | 0.91100713 |
| 83 | MP0004885_abnormal_endolymph | 0.90225357 |
| 84 | MP0002272_abnormal_nervous_system | 0.89074056 |
| 85 | MP0001243_abnormal_dermal_layer | 0.87883732 |
| 86 | MP0001502_abnormal_circadian_rhythm | 0.87611322 |
| 87 | MP0003252_abnormal_bile_duct | 0.87481953 |
| 88 | MP0000749_muscle_degeneration | 0.85673196 |
| 89 | MP0010678_abnormal_skin_adnexa | 0.82345368 |
| 90 | MP0008932_abnormal_embryonic_tissue | 0.82158990 |
| 91 | MP0000647_abnormal_sebaceous_gland | 0.80479985 |
| 92 | MP0003698_abnormal_male_reproductive | 0.80003026 |
| 93 | MP0002163_abnormal_gland_morphology | 0.75860033 |
| 94 | MP0002184_abnormal_innervation | 0.74740183 |
| 95 | MP0004084_abnormal_cardiac_muscle | 0.71702118 |
| 96 | MP0005389_reproductive_system_phenotype | 0.71021722 |
| 97 | MP0009250_abnormal_appendicular_skeleto | 0.70553349 |
| 98 | MP0002282_abnormal_trachea_morphology | 0.66387799 |
| 99 | MP0002109_abnormal_limb_morphology | 0.65265648 |
| 100 | MP0003763_abnormal_thymus_physiology | 0.64652592 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic cysts (HP:0001737) | 3.44256920 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 3.15651592 |
| 3 | Molar tooth sign on MRI (HP:0002419) | 3.15651592 |
| 4 | Volvulus (HP:0002580) | 3.06089455 |
| 5 | Pancreatic fibrosis (HP:0100732) | 2.96400209 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 2.91596337 |
| 7 | Hypoproteinemia (HP:0003075) | 2.91202518 |
| 8 | Methylmalonic acidemia (HP:0002912) | 2.89853491 |
| 9 | Abnormality of the renal medulla (HP:0100957) | 2.88988265 |
| 10 | Palpebral edema (HP:0100540) | 2.85368179 |
| 11 | Nephronophthisis (HP:0000090) | 2.83079363 |
| 12 | Panhypogammaglobulinemia (HP:0003139) | 2.82937268 |
| 13 | B lymphocytopenia (HP:0010976) | 2.80460364 |
| 14 | Abnormality of the renal cortex (HP:0011035) | 2.75175009 |
| 15 | Thyroiditis (HP:0100646) | 2.73744138 |
| 16 | Increased CSF lactate (HP:0002490) | 2.73721156 |
| 17 | Abnormality of B cell number (HP:0010975) | 2.70734150 |
| 18 | Severe combined immunodeficiency (HP:0004430) | 2.69025989 |
| 19 | Acute necrotizing encephalopathy (HP:0006965) | 2.67180168 |
| 20 | Mitochondrial inheritance (HP:0001427) | 2.60108690 |
| 21 | Hypoplastic pelvis (HP:0008839) | 2.56360222 |
| 22 | True hermaphroditism (HP:0010459) | 2.54122183 |
| 23 | Metaphyseal dysplasia (HP:0100255) | 2.50915654 |
| 24 | Progressive macrocephaly (HP:0004481) | 2.49753668 |
| 25 | Type 2 muscle fiber atrophy (HP:0003554) | 2.42943410 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.37177654 |
| 27 | Hepatic necrosis (HP:0002605) | 2.35655900 |
| 28 | Abnormal protein glycosylation (HP:0012346) | 2.35184274 |
| 29 | Abnormal glycosylation (HP:0012345) | 2.35184274 |
| 30 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.35184274 |
| 31 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.35184274 |
| 32 | Hypothermia (HP:0002045) | 2.33346957 |
| 33 | Supernumerary spleens (HP:0009799) | 2.30973926 |
| 34 | Abnormal finger flexion creases (HP:0006143) | 2.29378559 |
| 35 | Bile duct proliferation (HP:0001408) | 2.27563460 |
| 36 | Abnormal biliary tract physiology (HP:0012439) | 2.27563460 |
| 37 | Fibular aplasia (HP:0002990) | 2.26779221 |
| 38 | Delayed CNS myelination (HP:0002188) | 2.26126935 |
| 39 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.22372078 |
| 40 | Increased serum lactate (HP:0002151) | 2.21773533 |
| 41 | Gonadotropin excess (HP:0000837) | 2.20989577 |
| 42 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.20553749 |
| 43 | Colon cancer (HP:0003003) | 2.19032337 |
| 44 | Renal Fanconi syndrome (HP:0001994) | 2.18645354 |
| 45 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.17442102 |
| 46 | Abnormality of the pons (HP:0007361) | 2.17168219 |
| 47 | Hepatocellular necrosis (HP:0001404) | 2.16019896 |
| 48 | Absent phalangeal crease (HP:0006109) | 2.15934616 |
| 49 | Hypoplastic iliac wings (HP:0002866) | 2.15721936 |
| 50 | Congenital stationary night blindness (HP:0007642) | 2.13602731 |
| 51 | Attenuation of retinal blood vessels (HP:0007843) | 2.13244771 |
| 52 | Asplenia (HP:0001746) | 2.12542061 |
| 53 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12429633 |
| 54 | 3-Methylglutaconic aciduria (HP:0003535) | 2.12222632 |
| 55 | Combined immunodeficiency (HP:0005387) | 2.11577489 |
| 56 | Acute encephalopathy (HP:0006846) | 2.11527174 |
| 57 | Tubulointerstitial nephritis (HP:0001970) | 2.10649871 |
| 58 | Methylmalonic aciduria (HP:0012120) | 2.10541698 |
| 59 | Renal cortical cysts (HP:0000803) | 2.08373006 |
| 60 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.08134618 |
| 61 | CNS hypomyelination (HP:0003429) | 2.03369202 |
| 62 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.99680616 |
| 63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.98949335 |
| 64 | Abnormal drinking behavior (HP:0030082) | 1.98492793 |
| 65 | Polydipsia (HP:0001959) | 1.98492793 |
| 66 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.98156645 |
| 67 | IgG deficiency (HP:0004315) | 1.94500236 |
| 68 | Abnormality of the prostate (HP:0008775) | 1.92406099 |
| 69 | Oligodactyly (hands) (HP:0001180) | 1.92141770 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.89734400 |
| 71 | Disproportionate short-trunk short stature (HP:0003521) | 1.89414476 |
| 72 | Abnormality of the metopic suture (HP:0005556) | 1.88216966 |
| 73 | Hypoplasia of the pons (HP:0012110) | 1.88166554 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.86811035 |
| 75 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.85189921 |
| 76 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.83874078 |
| 77 | Aplastic anemia (HP:0001915) | 1.81511092 |
| 78 | Carpal bone hypoplasia (HP:0001498) | 1.80258775 |
| 79 | Muscle fiber atrophy (HP:0100295) | 1.78779879 |
| 80 | Chronic hepatic failure (HP:0100626) | 1.77783528 |
| 81 | Progressive inability to walk (HP:0002505) | 1.77013658 |
| 82 | Cystic liver disease (HP:0006706) | 1.76844585 |
| 83 | Adactyly (HP:0009776) | 1.76720530 |
| 84 | Exertional dyspnea (HP:0002875) | 1.75225470 |
| 85 | Distal arthrogryposis (HP:0005684) | 1.74899350 |
| 86 | Prominent metopic ridge (HP:0005487) | 1.73914040 |
| 87 | Constricted visual fields (HP:0001133) | 1.73110779 |
| 88 | Dry hair (HP:0011359) | 1.73044513 |
| 89 | Neonatal respiratory distress (HP:0002643) | 1.72920719 |
| 90 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.71601057 |
| 91 | Pendular nystagmus (HP:0012043) | 1.71370857 |
| 92 | Optic nerve coloboma (HP:0000588) | 1.70793514 |
| 93 | Inability to walk (HP:0002540) | 1.69852962 |
| 94 | Eosinophilia (HP:0001880) | 1.69683060 |
| 95 | Optic disc pallor (HP:0000543) | 1.69438517 |
| 96 | Congenital hepatic fibrosis (HP:0002612) | 1.66760888 |
| 97 | Short middle phalanx of the 5th finger (HP:0004220) | 1.65838385 |
| 98 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.65573146 |
| 99 | Type I transferrin isoform profile (HP:0003642) | 1.61990093 |
| 100 | Abnormality of vitamin B metabolism (HP:0004340) | 1.61870271 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.01184990 |
| 2 | EIF2AK3 | 3.31513297 |
| 3 | TAOK3 | 3.01989226 |
| 4 | STK16 | 2.72667831 |
| 5 | TXK | 2.48524139 |
| 6 | SRPK1 | 2.47123796 |
| 7 | NUAK1 | 2.38211925 |
| 8 | FRK | 2.30812031 |
| 9 | TRIM28 | 2.23388539 |
| 10 | VRK2 | 2.04118419 |
| 11 | WNK3 | 1.96662511 |
| 12 | NEK1 | 1.91009336 |
| 13 | PLK4 | 1.86426573 |
| 14 | MKNK1 | 1.77559056 |
| 15 | TSSK6 | 1.75403654 |
| 16 | GRK1 | 1.74428467 |
| 17 | TIE1 | 1.70306299 |
| 18 | MKNK2 | 1.65656493 |
| 19 | ZAK | 1.62210180 |
| 20 | PLK3 | 1.56423321 |
| 21 | CDK8 | 1.56057800 |
| 22 | BUB1 | 1.53689150 |
| 23 | MST4 | 1.52632521 |
| 24 | BCR | 1.49464676 |
| 25 | BMPR1B | 1.49389038 |
| 26 | MAP3K4 | 1.47891417 |
| 27 | TNIK | 1.37831324 |
| 28 | SCYL2 | 1.34700784 |
| 29 | VRK1 | 1.31517054 |
| 30 | PHKG1 | 1.29869649 |
| 31 | PHKG2 | 1.29869649 |
| 32 | EIF2AK1 | 1.28563786 |
| 33 | ADRBK2 | 1.28487475 |
| 34 | OXSR1 | 1.25297381 |
| 35 | ERBB3 | 1.25107788 |
| 36 | RPS6KA4 | 1.24637237 |
| 37 | CSNK1G1 | 1.19306617 |
| 38 | STK39 | 1.18838105 |
| 39 | TLK1 | 1.15662710 |
| 40 | CSNK1G2 | 1.15401152 |
| 41 | MAPKAPK3 | 1.15207573 |
| 42 | MAP2K7 | 1.14418595 |
| 43 | CSNK1G3 | 1.13666288 |
| 44 | BRSK2 | 1.13637775 |
| 45 | PBK | 1.08220027 |
| 46 | CSNK1A1L | 1.03341794 |
| 47 | PLK2 | 1.03105056 |
| 48 | PASK | 1.01931927 |
| 49 | WNK4 | 0.99421018 |
| 50 | PINK1 | 0.98945885 |
| 51 | TEC | 0.96642243 |
| 52 | CDK19 | 0.93665855 |
| 53 | ACVR1B | 0.92914192 |
| 54 | MAPK13 | 0.91843750 |
| 55 | PIK3CG | 0.91662840 |
| 56 | TGFBR1 | 0.91450730 |
| 57 | DAPK1 | 0.90539488 |
| 58 | EIF2AK2 | 0.89241389 |
| 59 | OBSCN | 0.83640164 |
| 60 | TAF1 | 0.80909179 |
| 61 | SIK3 | 0.78188071 |
| 62 | CCNB1 | 0.70924767 |
| 63 | CLK1 | 0.70556944 |
| 64 | BCKDK | 0.70358684 |
| 65 | ATR | 0.67524761 |
| 66 | NEK2 | 0.64920384 |
| 67 | JAK3 | 0.64615503 |
| 68 | MUSK | 0.64520547 |
| 69 | CHEK2 | 0.62116946 |
| 70 | RPS6KA5 | 0.58843240 |
| 71 | PLK1 | 0.58670989 |
| 72 | AKT3 | 0.58517724 |
| 73 | PRKCE | 0.57314070 |
| 74 | STK3 | 0.55618739 |
| 75 | MINK1 | 0.52809928 |
| 76 | ATM | 0.50549298 |
| 77 | TTK | 0.48949961 |
| 78 | DYRK2 | 0.44309839 |
| 79 | ITK | 0.43528721 |
| 80 | AURKB | 0.42442414 |
| 81 | CAMKK2 | 0.41682704 |
| 82 | MAP3K14 | 0.41669271 |
| 83 | CDC7 | 0.41256045 |
| 84 | TRPM7 | 0.41081182 |
| 85 | PIK3CA | 0.40640844 |
| 86 | PAK6 | 0.39445494 |
| 87 | FLT3 | 0.38374337 |
| 88 | KDR | 0.36203345 |
| 89 | DYRK3 | 0.36049945 |
| 90 | BMPR2 | 0.33254243 |
| 91 | CSNK2A1 | 0.33096279 |
| 92 | MAP2K6 | 0.31105942 |
| 93 | PAK3 | 0.30541343 |
| 94 | WNK1 | 0.29786049 |
| 95 | CSNK1A1 | 0.28425799 |
| 96 | PRKCQ | 0.28172317 |
| 97 | GRK5 | 0.27307906 |
| 98 | KIT | 0.25907220 |
| 99 | CSNK2A2 | 0.25613035 |
| 100 | PRKG1 | 0.24568237 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.57156870 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.36112038 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.09202171 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.98161935 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.66239363 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.42848490 |
| 7 | RNA degradation_Homo sapiens_hsa03018 | 2.38609034 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.33321032 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.25114749 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.24281987 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.16412609 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.06246751 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 2.02812765 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.02477776 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.99024745 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.98679140 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.98616995 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.94651958 |
| 19 | Spliceosome_Homo sapiens_hsa03040 | 1.86637048 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.82873529 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.76505876 |
| 22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.63943267 |
| 23 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.63917198 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.61897682 |
| 25 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.47603325 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45719022 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.41577307 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.41536399 |
| 29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.38452854 |
| 30 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.37407621 |
| 31 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.36044851 |
| 32 | Base excision repair_Homo sapiens_hsa03410 | 1.32826422 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30661994 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.30302975 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25546533 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.23143239 |
| 37 | Phototransduction_Homo sapiens_hsa04744 | 1.15292666 |
| 38 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.15207563 |
| 39 | Alzheimers disease_Homo sapiens_hsa05010 | 1.15175592 |
| 40 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.06134161 |
| 41 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.03594028 |
| 42 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.01942459 |
| 43 | Taste transduction_Homo sapiens_hsa04742 | 0.99696592 |
| 44 | Cell cycle_Homo sapiens_hsa04110 | 0.92702287 |
| 45 | Olfactory transduction_Homo sapiens_hsa04740 | 0.92628628 |
| 46 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.91796784 |
| 47 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.90478382 |
| 48 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.85417527 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.83978618 |
| 50 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.83672408 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.83407713 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.80559570 |
| 53 | Salivary secretion_Homo sapiens_hsa04970 | 0.79876801 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.77503152 |
| 55 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.76116831 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74944801 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73579788 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.72408009 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71975786 |
| 60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.66509972 |
| 61 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.61000511 |
| 62 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.60951385 |
| 63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.60705092 |
| 64 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59216342 |
| 65 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58654539 |
| 66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.55497957 |
| 67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.55090110 |
| 68 | Peroxisome_Homo sapiens_hsa04146 | 0.54800176 |
| 69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.53240334 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53040620 |
| 71 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.52582825 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50201879 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49052711 |
| 74 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48163526 |
| 75 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46509663 |
| 76 | Morphine addiction_Homo sapiens_hsa05032 | 0.44893263 |
| 77 | Nicotine addiction_Homo sapiens_hsa05033 | 0.44457184 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.43989799 |
| 79 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42263905 |
| 80 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.38545570 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.37848044 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33564958 |
| 83 | GABAergic synapse_Homo sapiens_hsa04727 | 0.33374828 |
| 84 | Long-term depression_Homo sapiens_hsa04730 | 0.33198753 |
| 85 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.32575896 |
| 86 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.32447851 |
| 87 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.31275535 |
| 88 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31133822 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26024086 |
| 90 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25665617 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.24986862 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.24976633 |
| 93 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.24527160 |
| 94 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.24298787 |
| 95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.24083240 |
| 96 | Measles_Homo sapiens_hsa05162 | 0.22874451 |
| 97 | Tight junction_Homo sapiens_hsa04530 | 0.22811734 |
| 98 | Viral myocarditis_Homo sapiens_hsa05416 | 0.20545720 |
| 99 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.19981889 |
| 100 | Alcoholism_Homo sapiens_hsa05034 | 0.18125072 |

