

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 6.06512915 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.99634813 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.60794330 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.60794330 |
| 5 | viral transcription (GO:0019083) | 5.53213518 |
| 6 | translational termination (GO:0006415) | 5.49768628 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.90957307 |
| 8 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.86888256 |
| 9 | ribosomal large subunit biogenesis (GO:0042273) | 4.86204544 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 4.85083103 |
| 11 | protein targeting to ER (GO:0045047) | 4.74409806 |
| 12 | translational elongation (GO:0006414) | 4.71938971 |
| 13 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.57369967 |
| 14 | protein localization to endoplasmic reticulum (GO:0070972) | 4.49606693 |
| 15 | translational initiation (GO:0006413) | 4.36046410 |
| 16 | DNA deamination (GO:0045006) | 4.34262475 |
| 17 | respiratory electron transport chain (GO:0022904) | 4.32041542 |
| 18 | cellular protein complex disassembly (GO:0043624) | 4.27738481 |
| 19 | electron transport chain (GO:0022900) | 4.23545594 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.18237185 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.18237185 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 4.18237185 |
| 23 | regulation of mitochondrial translation (GO:0070129) | 4.08569894 |
| 24 | maturation of SSU-rRNA (GO:0030490) | 4.03834371 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.02543283 |
| 26 | viral life cycle (GO:0019058) | 4.02363378 |
| 27 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.97801934 |
| 28 | ribosomal small subunit biogenesis (GO:0042274) | 3.83032370 |
| 29 | protein complex biogenesis (GO:0070271) | 3.81747099 |
| 30 | regulation of penile erection (GO:0060405) | 3.80168850 |
| 31 | oxidative phosphorylation (GO:0006119) | 3.77326614 |
| 32 | positive regulation of prostaglandin secretion (GO:0032308) | 3.66740084 |
| 33 | translation (GO:0006412) | 3.62853905 |
| 34 | protein complex disassembly (GO:0043241) | 3.60755127 |
| 35 | rRNA modification (GO:0000154) | 3.57358641 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46611063 |
| 37 | macromolecular complex disassembly (GO:0032984) | 3.45001271 |
| 38 | rRNA methylation (GO:0031167) | 3.38800858 |
| 39 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.37487133 |
| 40 | seminiferous tubule development (GO:0072520) | 3.36142405 |
| 41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.30126724 |
| 42 | purine nucleotide salvage (GO:0032261) | 3.27109059 |
| 43 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.26841253 |
| 44 | purine nucleobase biosynthetic process (GO:0009113) | 3.21193125 |
| 45 | CENP-A containing nucleosome assembly (GO:0034080) | 3.19773198 |
| 46 | cellular component biogenesis (GO:0044085) | 3.15887636 |
| 47 | chromatin remodeling at centromere (GO:0031055) | 3.15067141 |
| 48 | formation of translation preinitiation complex (GO:0001731) | 3.12041328 |
| 49 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.10146556 |
| 50 | protein K6-linked ubiquitination (GO:0085020) | 3.09650073 |
| 51 | chaperone-mediated protein transport (GO:0072321) | 3.08681973 |
| 52 | mRNA catabolic process (GO:0006402) | 3.06168504 |
| 53 | protein targeting to mitochondrion (GO:0006626) | 3.04034833 |
| 54 | nucleobase biosynthetic process (GO:0046112) | 3.03153731 |
| 55 | peptidyl-histidine modification (GO:0018202) | 3.01611097 |
| 56 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.01489829 |
| 57 | ATP biosynthetic process (GO:0006754) | 3.00688955 |
| 58 | sequestering of actin monomers (GO:0042989) | 3.00397585 |
| 59 | mismatch repair (GO:0006298) | 2.99745018 |
| 60 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.98450771 |
| 61 | protein targeting to membrane (GO:0006612) | 2.97174918 |
| 62 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.96209417 |
| 63 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.95734271 |
| 64 | negative regulation of ligase activity (GO:0051352) | 2.94048944 |
| 65 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.94048944 |
| 66 | spliceosomal snRNP assembly (GO:0000387) | 2.92867603 |
| 67 | negative regulation of B cell apoptotic process (GO:0002903) | 2.92691011 |
| 68 | purine-containing compound salvage (GO:0043101) | 2.91675782 |
| 69 | maturation of 5.8S rRNA (GO:0000460) | 2.90389383 |
| 70 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.86827954 |
| 71 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.84959740 |
| 72 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.83755610 |
| 73 | negative regulation by host of viral transcription (GO:0043922) | 2.83108219 |
| 74 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.82105881 |
| 75 | RNA catabolic process (GO:0006401) | 2.81983673 |
| 76 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.81820951 |
| 77 | regulation of prostaglandin secretion (GO:0032306) | 2.80766339 |
| 78 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.80482829 |
| 79 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.80482829 |
| 80 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.80482829 |
| 81 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.80336762 |
| 82 | proteasome assembly (GO:0043248) | 2.79539432 |
| 83 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.78642069 |
| 84 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.78642069 |
| 85 | meiosis I (GO:0007127) | 2.77394037 |
| 86 | sleep (GO:0030431) | 2.77076059 |
| 87 | establishment of protein localization to mitochondrion (GO:0072655) | 2.76514458 |
| 88 | rRNA processing (GO:0006364) | 2.76167811 |
| 89 | rRNA metabolic process (GO:0016072) | 2.75438681 |
| 90 | male meiosis I (GO:0007141) | 2.74396154 |
| 91 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.74366470 |
| 92 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.74366470 |
| 93 | inner mitochondrial membrane organization (GO:0007007) | 2.72822426 |
| 94 | histone exchange (GO:0043486) | 2.72084642 |
| 95 | adenosine metabolic process (GO:0046085) | 2.70488753 |
| 96 | grooming behavior (GO:0007625) | 2.69252816 |
| 97 | nucleoside transmembrane transport (GO:1901642) | 2.68439975 |
| 98 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.66912361 |
| 99 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.66912361 |
| 100 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.66505553 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.84703564 |
| 2 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.32250395 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.15613337 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.01341074 |
| 5 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.38622973 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.35218697 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.31269320 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.26365280 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.25043531 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 3.18705926 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.06984182 |
| 12 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.94603855 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.87861743 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80152684 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.73592638 |
| 16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.56955556 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.51235666 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.48299269 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.44502780 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.44250159 |
| 21 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.41311681 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.34501817 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.30396130 |
| 24 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.16838711 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.16217359 |
| 26 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.13959785 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.11284894 |
| 28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.05139528 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.02998263 |
| 30 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.99206405 |
| 31 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.95005798 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.91583472 |
| 33 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.90925438 |
| 34 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.83375986 |
| 35 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.80730002 |
| 36 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.70647955 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.65159658 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.62099824 |
| 39 | EWS_26573619_Chip-Seq_HEK293_Human | 1.60723592 |
| 40 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.60392820 |
| 41 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.58379983 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.57330077 |
| 43 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.56708700 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.55738132 |
| 45 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.46316522 |
| 46 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.45291308 |
| 47 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.45103433 |
| 48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.44721069 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.43995935 |
| 50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.41685514 |
| 51 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41164158 |
| 52 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.39806245 |
| 53 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.34733029 |
| 54 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31890796 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31204844 |
| 56 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.29371022 |
| 57 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.27932058 |
| 58 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.26696285 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26519752 |
| 60 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.25906393 |
| 61 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.21075419 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21064880 |
| 63 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.19394576 |
| 64 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.18159903 |
| 65 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.13114438 |
| 66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.12972046 |
| 67 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.12798589 |
| 68 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.09452315 |
| 69 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.03188138 |
| 70 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01989131 |
| 71 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.97975883 |
| 72 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.97838685 |
| 73 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.97234414 |
| 74 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.94066800 |
| 75 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.93444287 |
| 76 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.92195979 |
| 77 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.91573632 |
| 78 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.90951504 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90470674 |
| 80 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.88485024 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.88087157 |
| 82 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.88087157 |
| 83 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.87641646 |
| 84 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.86533804 |
| 85 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.86331664 |
| 86 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.85844204 |
| 87 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.85166307 |
| 88 | AR_20517297_ChIP-Seq_VCAP_Human | 0.84153293 |
| 89 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.83491554 |
| 90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83275408 |
| 91 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.82044255 |
| 92 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.80448557 |
| 93 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.80448557 |
| 94 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.79336404 |
| 95 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.78780270 |
| 96 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.78285946 |
| 97 | P300_19829295_ChIP-Seq_ESCs_Human | 0.77764583 |
| 98 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.77085610 |
| 99 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.75451005 |
| 100 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.75367039 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.41933496 |
| 2 | MP0000372_irregular_coat_pigmentation | 4.36536027 |
| 3 | MP0008058_abnormal_DNA_repair | 3.45388448 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.34801976 |
| 5 | MP0009697_abnormal_copulation | 3.03996655 |
| 6 | MP0005075_abnormal_melanosome_morpholog | 2.83697736 |
| 7 | MP0003718_maternal_effect | 2.80903914 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.69881102 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.54280778 |
| 10 | MP0002822_catalepsy | 2.43800184 |
| 11 | MP0003646_muscle_fatigue | 2.25451276 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.11897674 |
| 13 | MP0003186_abnormal_redox_activity | 2.07918428 |
| 14 | MP0002102_abnormal_ear_morphology | 2.06096846 |
| 15 | MP0003786_premature_aging | 1.95807458 |
| 16 | MP0003136_yellow_coat_color | 1.94803532 |
| 17 | MP0005646_abnormal_pituitary_gland | 1.87869829 |
| 18 | MP0005645_abnormal_hypothalamus_physiol | 1.78775820 |
| 19 | MP0005410_abnormal_fertilization | 1.78186717 |
| 20 | MP0004957_abnormal_blastocyst_morpholog | 1.78037330 |
| 21 | MP0002938_white_spotting | 1.71042017 |
| 22 | MP0005408_hypopigmentation | 1.67366205 |
| 23 | MP0002928_abnormal_bile_duct | 1.64095754 |
| 24 | MP0002095_abnormal_skin_pigmentation | 1.63299633 |
| 25 | MP0002160_abnormal_reproductive_system | 1.53447464 |
| 26 | MP0003693_abnormal_embryo_hatching | 1.53069660 |
| 27 | MP0001984_abnormal_olfaction | 1.50542994 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.49224559 |
| 29 | MP0005083_abnormal_biliary_tract | 1.47622650 |
| 30 | MP0001764_abnormal_homeostasis | 1.47510395 |
| 31 | MP0005253_abnormal_eye_physiology | 1.42151443 |
| 32 | MP0003880_abnormal_central_pattern | 1.41194908 |
| 33 | MP0003077_abnormal_cell_cycle | 1.40057525 |
| 34 | MP0001293_anophthalmia | 1.38230612 |
| 35 | MP0005174_abnormal_tail_pigmentation | 1.32267490 |
| 36 | MP0005084_abnormal_gallbladder_morpholo | 1.28813871 |
| 37 | MP0005171_absent_coat_pigmentation | 1.26705575 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.26061235 |
| 39 | MP0006054_spinal_hemorrhage | 1.24387727 |
| 40 | MP0004133_heterotaxia | 1.23627407 |
| 41 | MP0001835_abnormal_antigen_presentation | 1.21979602 |
| 42 | MP0003252_abnormal_bile_duct | 1.21071589 |
| 43 | MP0003111_abnormal_nucleus_morphology | 1.19582822 |
| 44 | MP0000465_gastrointestinal_hemorrhage | 1.19223707 |
| 45 | MP0005551_abnormal_eye_electrophysiolog | 1.19025559 |
| 46 | MP0005389_reproductive_system_phenotype | 1.14522806 |
| 47 | MP0005085_abnormal_gallbladder_physiolo | 1.14395125 |
| 48 | MP0002736_abnormal_nociception_after | 1.13589993 |
| 49 | MP0001929_abnormal_gametogenesis | 1.12047706 |
| 50 | MP0002090_abnormal_vision | 1.06884176 |
| 51 | MP0002148_abnormal_hypersensitivity_rea | 1.06052931 |
| 52 | MP0004142_abnormal_muscle_tone | 1.05311294 |
| 53 | MP0005377_hearing/vestibular/ear_phenot | 1.03512120 |
| 54 | MP0003878_abnormal_ear_physiology | 1.03512120 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 1.03004915 |
| 56 | MP0005671_abnormal_response_to | 1.02958624 |
| 57 | MP0002234_abnormal_pharynx_morphology | 1.02890519 |
| 58 | MP0005395_other_phenotype | 1.02268086 |
| 59 | MP0000613_abnormal_salivary_gland | 1.01034900 |
| 60 | MP0002006_tumorigenesis | 0.99473666 |
| 61 | MP0002210_abnormal_sex_determination | 0.98934975 |
| 62 | MP0002019_abnormal_tumor_incidence | 0.94845578 |
| 63 | MP0001881_abnormal_mammary_gland | 0.94173660 |
| 64 | MP0004145_abnormal_muscle_electrophysio | 0.93602738 |
| 65 | MP0006276_abnormal_autonomic_nervous | 0.92648112 |
| 66 | MP0010368_abnormal_lymphatic_system | 0.91217787 |
| 67 | MP0010386_abnormal_urinary_bladder | 0.90844455 |
| 68 | MP0006035_abnormal_mitochondrial_morpho | 0.90740565 |
| 69 | MP0002653_abnormal_ependyma_morphology | 0.90656567 |
| 70 | MP0004134_abnormal_chest_morphology | 0.89419960 |
| 71 | MP0010030_abnormal_orbit_morphology | 0.88399024 |
| 72 | MP0001119_abnormal_female_reproductive | 0.88212398 |
| 73 | MP0000631_abnormal_neuroendocrine_gland | 0.87560399 |
| 74 | MP0005319_abnormal_enzyme/_coenzyme | 0.86600955 |
| 75 | MP0004147_increased_porphyrin_level | 0.84386874 |
| 76 | MP0008875_abnormal_xenobiotic_pharmacok | 0.82855242 |
| 77 | MP0008932_abnormal_embryonic_tissue | 0.82570732 |
| 78 | MP0000653_abnormal_sex_gland | 0.81573313 |
| 79 | MP0008007_abnormal_cellular_replicative | 0.80646846 |
| 80 | MP0004808_abnormal_hematopoietic_stem | 0.79601012 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.79437590 |
| 82 | MP0002751_abnormal_autonomic_nervous | 0.79102528 |
| 83 | MP0001501_abnormal_sleep_pattern | 0.78762723 |
| 84 | MP0005391_vision/eye_phenotype | 0.77324115 |
| 85 | MP0009278_abnormal_bone_marrow | 0.76401777 |
| 86 | MP0001145_abnormal_male_reproductive | 0.74036021 |
| 87 | MP0008995_early_reproductive_senescence | 0.72932513 |
| 88 | MP0003567_abnormal_fetal_cardiomyocyte | 0.72901796 |
| 89 | MP0000516_abnormal_urinary_system | 0.72406432 |
| 90 | MP0005367_renal/urinary_system_phenotyp | 0.72406432 |
| 91 | MP0003698_abnormal_male_reproductive | 0.72256158 |
| 92 | MP0008872_abnormal_physiological_respon | 0.71672320 |
| 93 | MP0003763_abnormal_thymus_physiology | 0.69656626 |
| 94 | MP0001879_abnormal_lymphatic_vessel | 0.69626601 |
| 95 | MP0000627_abnormal_mammary_gland | 0.68622034 |
| 96 | MP0009765_abnormal_xenobiotic_induced | 0.67066280 |
| 97 | MP0002398_abnormal_bone_marrow | 0.66633329 |
| 98 | MP0000689_abnormal_spleen_morphology | 0.65612815 |
| 99 | MP0001968_abnormal_touch/_nociception | 0.62857425 |
| 100 | MP0000538_abnormal_urinary_bladder | 0.62726412 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.69985972 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.58885603 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.49698823 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.41138992 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 4.35974551 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.34442676 |
| 7 | Increased CSF lactate (HP:0002490) | 4.25161219 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 4.23450338 |
| 9 | Acute encephalopathy (HP:0006846) | 3.99110548 |
| 10 | Reticulocytopenia (HP:0001896) | 3.97720498 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.82713777 |
| 12 | Cerebral edema (HP:0002181) | 3.72950183 |
| 13 | Hepatic necrosis (HP:0002605) | 3.71926845 |
| 14 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.65431579 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.25796533 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.06053051 |
| 17 | Abnormal number of erythroid precursors (HP:0012131) | 3.04000882 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 3.03479131 |
| 19 | Exertional dyspnea (HP:0002875) | 2.93035906 |
| 20 | Type I transferrin isoform profile (HP:0003642) | 2.90727551 |
| 21 | Macrocytic anemia (HP:0001972) | 2.86654426 |
| 22 | Increased muscle lipid content (HP:0009058) | 2.85858547 |
| 23 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.79202051 |
| 24 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.78147115 |
| 25 | Oral leukoplakia (HP:0002745) | 2.71892211 |
| 26 | Respiratory failure (HP:0002878) | 2.70531421 |
| 27 | Hypochromic microcytic anemia (HP:0004840) | 2.63159043 |
| 28 | Pancreatic cysts (HP:0001737) | 2.62838900 |
| 29 | Lethargy (HP:0001254) | 2.61200939 |
| 30 | Medial flaring of the eyebrow (HP:0010747) | 2.59248317 |
| 31 | Degeneration of anterior horn cells (HP:0002398) | 2.58978367 |
| 32 | Abnormality of the anterior horn cell (HP:0006802) | 2.58978367 |
| 33 | Reduced antithrombin III activity (HP:0001976) | 2.54704486 |
| 34 | Hyperglycinemia (HP:0002154) | 2.52914755 |
| 35 | Increased serum lactate (HP:0002151) | 2.52853390 |
| 36 | Pancytopenia (HP:0001876) | 2.51243479 |
| 37 | Lactic acidosis (HP:0003128) | 2.50670592 |
| 38 | Methylmalonic acidemia (HP:0002912) | 2.49531108 |
| 39 | Pallor (HP:0000980) | 2.44360980 |
| 40 | Exercise intolerance (HP:0003546) | 2.42386947 |
| 41 | Respiratory difficulties (HP:0002880) | 2.39444676 |
| 42 | Pancreatic fibrosis (HP:0100732) | 2.37676792 |
| 43 | Abnormal protein glycosylation (HP:0012346) | 2.33933265 |
| 44 | Abnormal glycosylation (HP:0012345) | 2.33933265 |
| 45 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.33933265 |
| 46 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.33933265 |
| 47 | Type II lissencephaly (HP:0007260) | 2.33302368 |
| 48 | Septo-optic dysplasia (HP:0100842) | 2.25896851 |
| 49 | Optic disc pallor (HP:0000543) | 2.23768411 |
| 50 | CNS demyelination (HP:0007305) | 2.21062491 |
| 51 | Congenital stationary night blindness (HP:0007642) | 2.16685944 |
| 52 | Congenital, generalized hypertrichosis (HP:0004540) | 2.15422433 |
| 53 | Abnormality of methionine metabolism (HP:0010901) | 2.13733725 |
| 54 | Absent thumb (HP:0009777) | 2.13163657 |
| 55 | Hyperglycinuria (HP:0003108) | 2.10153460 |
| 56 | Abnormal biliary tract physiology (HP:0012439) | 2.09958656 |
| 57 | Bile duct proliferation (HP:0001408) | 2.09958656 |
| 58 | Methylmalonic aciduria (HP:0012120) | 2.07775358 |
| 59 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.06790737 |
| 60 | 3-Methylglutaconic aciduria (HP:0003535) | 2.06336500 |
| 61 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.06143365 |
| 62 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.05889565 |
| 63 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.05889565 |
| 64 | Type 2 muscle fiber atrophy (HP:0003554) | 2.04989910 |
| 65 | Progressive muscle weakness (HP:0003323) | 2.04959192 |
| 66 | Abnormality of the renal cortex (HP:0011035) | 2.03482985 |
| 67 | Cerebellar dysplasia (HP:0007033) | 2.02001289 |
| 68 | Severe combined immunodeficiency (HP:0004430) | 2.01266618 |
| 69 | Leukodystrophy (HP:0002415) | 1.98695523 |
| 70 | Abnormality of B cell number (HP:0010975) | 1.95655636 |
| 71 | Abnormality of serum amino acid levels (HP:0003112) | 1.90853550 |
| 72 | Homocystinuria (HP:0002156) | 1.90086352 |
| 73 | Abnormality of homocysteine metabolism (HP:0010919) | 1.90086352 |
| 74 | Attenuation of retinal blood vessels (HP:0007843) | 1.89446180 |
| 75 | Ketosis (HP:0001946) | 1.88826529 |
| 76 | IgM deficiency (HP:0002850) | 1.87686708 |
| 77 | Hypothermia (HP:0002045) | 1.86254105 |
| 78 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.86043847 |
| 79 | Dicarboxylic aciduria (HP:0003215) | 1.86043847 |
| 80 | Congenital primary aphakia (HP:0007707) | 1.84414826 |
| 81 | Rib fusion (HP:0000902) | 1.81531365 |
| 82 | Chromsome breakage (HP:0040012) | 1.79742909 |
| 83 | Triphalangeal thumb (HP:0001199) | 1.78404144 |
| 84 | B lymphocytopenia (HP:0010976) | 1.77077053 |
| 85 | Hypoplasia of the pons (HP:0012110) | 1.75188298 |
| 86 | Emotional lability (HP:0000712) | 1.74719370 |
| 87 | Supernumerary spleens (HP:0009799) | 1.74243634 |
| 88 | Hypoalbuminemia (HP:0003073) | 1.73961394 |
| 89 | Abnormal albumin level (HP:0012116) | 1.73961394 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.72979543 |
| 91 | Hyperalaninemia (HP:0003348) | 1.72979543 |
| 92 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.72979543 |
| 93 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.72046378 |
| 94 | Abnormal ciliary motility (HP:0012262) | 1.71562747 |
| 95 | Asplenia (HP:0001746) | 1.71199083 |
| 96 | Thrombocytosis (HP:0001894) | 1.70904053 |
| 97 | Abnormality of renal resorption (HP:0011038) | 1.70626242 |
| 98 | Tubular atrophy (HP:0000092) | 1.70172556 |
| 99 | Abnormality of the pons (HP:0007361) | 1.70060969 |
| 100 | Gait imbalance (HP:0002141) | 1.69706766 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 4.43142060 |
| 2 | VRK2 | 3.68766777 |
| 3 | BCKDK | 3.66732343 |
| 4 | SCYL2 | 3.00616017 |
| 5 | MAP4K2 | 2.65486541 |
| 6 | TRIM28 | 2.58784468 |
| 7 | TAOK3 | 2.55720952 |
| 8 | EIF2AK1 | 2.47018126 |
| 9 | TXK | 2.41060648 |
| 10 | PDK2 | 2.37968648 |
| 11 | PBK | 2.34305938 |
| 12 | KDR | 2.27958797 |
| 13 | BUB1 | 2.15203424 |
| 14 | ZAK | 1.99778778 |
| 15 | BMPR1B | 1.96248484 |
| 16 | STK16 | 1.94718651 |
| 17 | MAP2K7 | 1.90033593 |
| 18 | FRK | 1.88588106 |
| 19 | CDC7 | 1.82344008 |
| 20 | MST4 | 1.67900394 |
| 21 | CCNB1 | 1.62889291 |
| 22 | SIK3 | 1.59344777 |
| 23 | ACVR1B | 1.52182016 |
| 24 | EIF2AK3 | 1.43989112 |
| 25 | BMPR2 | 1.41149585 |
| 26 | FLT3 | 1.36860734 |
| 27 | TAF1 | 1.36109489 |
| 28 | WEE1 | 1.33041627 |
| 29 | NUAK1 | 1.32472186 |
| 30 | VRK1 | 1.29370587 |
| 31 | NME2 | 1.17794366 |
| 32 | TEC | 1.13839007 |
| 33 | BCR | 1.11450287 |
| 34 | SRPK1 | 1.09632284 |
| 35 | OXSR1 | 1.06868400 |
| 36 | KIT | 1.02499441 |
| 37 | WNK3 | 0.99483241 |
| 38 | BRSK2 | 0.98184540 |
| 39 | PLK3 | 0.96580251 |
| 40 | FES | 0.94353901 |
| 41 | MAP4K1 | 0.91617344 |
| 42 | PASK | 0.88384296 |
| 43 | TNK2 | 0.85303010 |
| 44 | TLK1 | 0.84628431 |
| 45 | PLK4 | 0.83013755 |
| 46 | AURKB | 0.82432400 |
| 47 | GRK1 | 0.81078185 |
| 48 | ERBB3 | 0.79424437 |
| 49 | ZAP70 | 0.79120466 |
| 50 | TSSK6 | 0.78641287 |
| 51 | RPS6KA4 | 0.78419913 |
| 52 | ATR | 0.77528497 |
| 53 | PIM2 | 0.76990496 |
| 54 | PIK3CG | 0.74823479 |
| 55 | MKNK1 | 0.70613058 |
| 56 | TESK2 | 0.69557236 |
| 57 | TTK | 0.69283100 |
| 58 | RPS6KA5 | 0.68957354 |
| 59 | TNIK | 0.68742242 |
| 60 | ADRBK2 | 0.67286870 |
| 61 | PLK1 | 0.65787680 |
| 62 | GRK6 | 0.65200342 |
| 63 | CSNK2A2 | 0.63730973 |
| 64 | ILK | 0.63258106 |
| 65 | ITK | 0.61539902 |
| 66 | MAP3K4 | 0.61457587 |
| 67 | SYK | 0.59955533 |
| 68 | AURKA | 0.58885818 |
| 69 | CHEK2 | 0.58684286 |
| 70 | INSRR | 0.54458526 |
| 71 | PINK1 | 0.53432255 |
| 72 | CDK3 | 0.52805852 |
| 73 | MST1R | 0.51374869 |
| 74 | ADRBK1 | 0.50982377 |
| 75 | CSNK2A1 | 0.50308534 |
| 76 | MATK | 0.48945038 |
| 77 | MELK | 0.46210048 |
| 78 | TGFBR1 | 0.46170209 |
| 79 | MUSK | 0.43674837 |
| 80 | CDK8 | 0.40205960 |
| 81 | BTK | 0.36986959 |
| 82 | PLK2 | 0.33820536 |
| 83 | CSNK1A1 | 0.32654122 |
| 84 | ERBB4 | 0.30455541 |
| 85 | CAMK1 | 0.29636559 |
| 86 | LCK | 0.29288067 |
| 87 | IKBKB | 0.29045647 |
| 88 | LYN | 0.27932787 |
| 89 | CHEK1 | 0.27899111 |
| 90 | IGF1R | 0.27277776 |
| 91 | PAK1 | 0.26938656 |
| 92 | NME1 | 0.26422451 |
| 93 | NEK2 | 0.25826593 |
| 94 | ATM | 0.25820208 |
| 95 | MAPK13 | 0.25737770 |
| 96 | STK4 | 0.25385985 |
| 97 | CSF1R | 0.24935316 |
| 98 | TBK1 | 0.23731563 |
| 99 | EIF2AK2 | 0.23397464 |
| 100 | CDK4 | 0.22241791 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.71416414 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.11345089 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 4.01987200 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.50224697 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 2.59470284 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.59324448 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.56715609 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.45358928 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.44808162 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.44556035 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.42698403 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.39987272 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.23758336 |
| 14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.05798228 |
| 15 | Protein export_Homo sapiens_hsa03060 | 2.02633759 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 2.02507480 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.80811303 |
| 18 | RNA transport_Homo sapiens_hsa03013 | 1.76536331 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.68165876 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.63230042 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.63057474 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.60394088 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.51834821 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.50187211 |
| 25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.45035425 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.38532323 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.35949762 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.31416241 |
| 29 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.28415412 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.25900060 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.21382847 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.20747393 |
| 33 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.19934783 |
| 34 | Purine metabolism_Homo sapiens_hsa00230 | 1.18706222 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.16386488 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.15798383 |
| 37 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.14383623 |
| 38 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.13477071 |
| 39 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.05087613 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.01558421 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.00094316 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.98589202 |
| 43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.98283267 |
| 44 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.97015018 |
| 45 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.82269219 |
| 46 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.80635480 |
| 47 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.79945064 |
| 48 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.77970989 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76070666 |
| 50 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.74916485 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.72215380 |
| 52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.69859897 |
| 53 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68993964 |
| 54 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.68855830 |
| 55 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.67893846 |
| 56 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.65610801 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.64076973 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.63705872 |
| 59 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.63513279 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62166609 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61165260 |
| 62 | Cell cycle_Homo sapiens_hsa04110 | 0.60116725 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.56936247 |
| 64 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.55786385 |
| 65 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53719645 |
| 66 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.53312895 |
| 67 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.53174537 |
| 68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53045568 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51362824 |
| 70 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.51228568 |
| 71 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51098569 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50576324 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47736766 |
| 74 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46770012 |
| 75 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.46769809 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.46441279 |
| 77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.44774102 |
| 78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.42400190 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41857993 |
| 80 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41325849 |
| 81 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.39519315 |
| 82 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.38758283 |
| 83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.38679877 |
| 84 | Olfactory transduction_Homo sapiens_hsa04740 | 0.37599302 |
| 85 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.37445942 |
| 86 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.34818880 |
| 87 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.34291164 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.34069981 |
| 89 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33743148 |
| 90 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.33718555 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31986401 |
| 92 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.31550444 |
| 93 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29790561 |
| 94 | Shigellosis_Homo sapiens_hsa05131 | 0.25392912 |
| 95 | Alcoholism_Homo sapiens_hsa05034 | 0.24227449 |
| 96 | ABC transporters_Homo sapiens_hsa02010 | 0.23333733 |
| 97 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.23218057 |
| 98 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.21432760 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.19768196 |
| 100 | Carbon metabolism_Homo sapiens_hsa01200 | 0.16898006 |

