EIF3I

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.46173286
2viral transcription (GO:0019083)5.82671792
3translational termination (GO:0006415)5.66971018
4ribosomal small subunit biogenesis (GO:0042274)5.59994507
5maturation of SSU-rRNA (GO:0030490)5.41148805
6translational elongation (GO:0006414)5.06170321
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.99727166
8cotranslational protein targeting to membrane (GO:0006613)4.88313938
9mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.87188130
10protein targeting to ER (GO:0045047)4.86612735
11* formation of translation preinitiation complex (GO:0001731)4.85597419
12ribosomal large subunit biogenesis (GO:0042273)4.76716785
13* translational initiation (GO:0006413)4.71046013
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.64125697
15establishment of protein localization to endoplasmic reticulum (GO:0072599)4.62487506
16protein localization to endoplasmic reticulum (GO:0070972)4.58984143
17viral life cycle (GO:0019058)4.44534236
18ribonucleoprotein complex biogenesis (GO:0022613)4.43155611
19cellular protein complex disassembly (GO:0043624)4.40070005
20establishment of integrated proviral latency (GO:0075713)4.26368861
21DNA strand elongation involved in DNA replication (GO:0006271)4.24678555
22energy coupled proton transport, down electrochemical gradient (GO:0015985)4.20484803
23ATP synthesis coupled proton transport (GO:0015986)4.20484803
24establishment of protein localization to mitochondrial membrane (GO:0090151)4.16533240
25DNA deamination (GO:0045006)4.16271907
26DNA strand elongation (GO:0022616)4.07095060
27telomere maintenance via semi-conservative replication (GO:0032201)4.06973215
28DNA replication checkpoint (GO:0000076)4.02660048
29regulation of mitochondrial translation (GO:0070129)3.98847996
30* translation (GO:0006412)3.93672065
31ribosome biogenesis (GO:0042254)3.93311799
32DNA replication initiation (GO:0006270)3.93212933
33chaperone-mediated protein transport (GO:0072321)3.92966184
34protein complex disassembly (GO:0043241)3.90880020
35protein localization to kinetochore (GO:0034501)3.89490189
36nucleobase biosynthetic process (GO:0046112)3.88696248
37proteasome assembly (GO:0043248)3.79800634
38rRNA processing (GO:0006364)3.77371160
39macromolecular complex disassembly (GO:0032984)3.68494964
40positive regulation of ligase activity (GO:0051351)3.67126964
41rRNA metabolic process (GO:0016072)3.63108779
42tRNA aminoacylation for protein translation (GO:0006418)3.62867213
43purine nucleobase biosynthetic process (GO:0009113)3.62482334
44rRNA modification (GO:0000154)3.61352113
45nucleobase-containing small molecule interconversion (GO:0015949)3.61080078
46nuclear-transcribed mRNA catabolic process (GO:0000956)3.59184842
47telomere maintenance via recombination (GO:0000722)3.59039684
48protein targeting to mitochondrion (GO:0006626)3.58848427
49amino acid activation (GO:0043038)3.57734419
50tRNA aminoacylation (GO:0043039)3.57734419
51regulation of ubiquitin-protein transferase activity (GO:0051438)3.55914582
52pseudouridine synthesis (GO:0001522)3.55879542
53DNA replication-dependent nucleosome organization (GO:0034723)3.55131984
54DNA replication-dependent nucleosome assembly (GO:0006335)3.55131984
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.54238805
56establishment of viral latency (GO:0019043)3.54086771
57DNA unwinding involved in DNA replication (GO:0006268)3.52951224
58cellular component biogenesis (GO:0044085)3.48223826
59regulation of ligase activity (GO:0051340)3.43842451
60oxidative phosphorylation (GO:0006119)3.42975969
61mRNA catabolic process (GO:0006402)3.41453908
62cullin deneddylation (GO:0010388)3.40298537
63mitotic metaphase plate congression (GO:0007080)3.40157104
64protein deneddylation (GO:0000338)3.39631692
65CENP-A containing nucleosome assembly (GO:0034080)3.38284910
66mitotic recombination (GO:0006312)3.38160988
67anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.37007275
68regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.35345724
69regulation of translational fidelity (GO:0006450)3.35014970
70telomere maintenance via telomere lengthening (GO:0010833)3.33948574
71spliceosomal snRNP assembly (GO:0000387)3.33904771
72RNA catabolic process (GO:0006401)3.29562082
73establishment of protein localization to mitochondrion (GO:0072655)3.28854419
74positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.28771842
75respiratory electron transport chain (GO:0022904)3.28443747
76chromatin remodeling at centromere (GO:0031055)3.28344930
77mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.27964637
78negative regulation of ligase activity (GO:0051352)3.24380038
79negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.24380038
80transcription elongation from RNA polymerase III promoter (GO:0006385)3.23102196
81termination of RNA polymerase III transcription (GO:0006386)3.23102196
82protein localization to mitochondrion (GO:0070585)3.22351289
83protein maturation by protein folding (GO:0022417)3.21597545
84IMP biosynthetic process (GO:0006188)3.20828063
85protein localization to chromosome, centromeric region (GO:0071459)3.20481727
86electron transport chain (GO:0022900)3.19706763
87DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.17275690
88ribosome assembly (GO:0042255)3.16669923
89pteridine-containing compound biosynthetic process (GO:0042559)3.14141459
90protein targeting to membrane (GO:0006612)3.13692019
91intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.12085772
92signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.12085772
93folic acid-containing compound biosynthetic process (GO:0009396)3.11998503
94nucleotide-excision repair, DNA gap filling (GO:0006297)3.11394845
95mitotic nuclear envelope disassembly (GO:0007077)3.10789866
96IMP metabolic process (GO:0046040)3.09998023
97signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.09039266
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.09039266
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.09039266
100positive regulation of cell cycle arrest (GO:0071158)3.08876283
101transcription-coupled nucleotide-excision repair (GO:0006283)3.07997317
102rRNA methylation (GO:0031167)3.05425908
103signal transduction involved in DNA integrity checkpoint (GO:0072401)3.04956471
104signal transduction involved in DNA damage checkpoint (GO:0072422)3.04956471
105protein complex biogenesis (GO:0070271)3.04897088
106guanosine-containing compound biosynthetic process (GO:1901070)3.04833643
107mitochondrial respiratory chain complex assembly (GO:0033108)3.04688868
108negative regulation of protein ubiquitination (GO:0031397)3.03659816
109DNA replication-independent nucleosome organization (GO:0034724)3.03266370
110DNA replication-independent nucleosome assembly (GO:0006336)3.03266370
111deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.03038391
112pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.01615251
113L-serine metabolic process (GO:0006563)3.01073783
114regulation of cellular amine metabolic process (GO:0033238)3.00871745
115antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.00682437
116signal transduction involved in cell cycle checkpoint (GO:0072395)3.00275786
117regulation of nuclear cell cycle DNA replication (GO:0033262)2.96488389
118maturation of 5.8S rRNA (GO:0000460)2.93106452
119mitotic sister chromatid segregation (GO:0000070)2.92075591
1207-methylguanosine mRNA capping (GO:0006370)2.91853504
121transcription from RNA polymerase I promoter (GO:0006360)2.90718780
122positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.90607428
123cell cycle G1/S phase transition (GO:0044843)2.89838479
124G1/S transition of mitotic cell cycle (GO:0000082)2.89838479
125viral mRNA export from host cell nucleus (GO:0046784)2.88828145
126attachment of spindle microtubules to kinetochore (GO:0008608)2.88441955
127metaphase plate congression (GO:0051310)2.88257358
128regulation of translation in response to stress (GO:0043555)2.87816565
129exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.87463605
130regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.87049565
131RNA capping (GO:0036260)2.86722762
1327-methylguanosine RNA capping (GO:0009452)2.86722762
133regulation of cellular amino acid metabolic process (GO:0006521)2.86205867
134spliceosomal complex assembly (GO:0000245)2.86147142
135ncRNA processing (GO:0034470)2.84683200

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.68744179
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.52652158
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.95982471
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.47645309
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.28618684
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.23717661
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.15175797
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.12355396
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.08698133
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.08268932
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.01655121
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.01452498
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.93920391
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.92165785
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.80503728
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.79215258
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.57916324
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.52365702
19XRN2_22483619_ChIP-Seq_HELA_Human2.43851862
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.35032244
21VDR_23849224_ChIP-Seq_CD4+_Human2.31350791
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.26551463
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18394670
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.13703045
25DCP1A_22483619_ChIP-Seq_HELA_Human2.08393967
26FOXP3_21729870_ChIP-Seq_TREG_Human2.06962641
27HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.03089252
28TTF2_22483619_ChIP-Seq_HELA_Human1.94580109
29GABP_19822575_ChIP-Seq_HepG2_Human1.94055803
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88174664
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87323364
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85549085
33POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.84610686
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.82501610
35YY1_21170310_ChIP-Seq_MESCs_Mouse1.80592186
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.73132295
37E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.72268931
38ELK1_19687146_ChIP-ChIP_HELA_Human1.68785440
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.66450059
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64230070
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63441816
42AR_21909140_ChIP-Seq_LNCAP_Human1.62162532
43SRF_21415370_ChIP-Seq_HL-1_Mouse1.60912358
44TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.59557982
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58789724
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.58185033
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51478407
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.50976108
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.50693279
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48840762
51CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.45516698
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.42520352
53CIITA_25753668_ChIP-Seq_RAJI_Human1.42273688
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.40914213
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.40070045
56YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39329309
57KDM5A_27292631_Chip-Seq_BREAST_Human1.39039312
58MYC_22102868_ChIP-Seq_BL_Human1.38729002
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.36029381
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.32828173
61PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32759302
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.31163431
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25258447
64CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25091433
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.24509512
66CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.23858603
67DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.20061113
68HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.19508136
69ELK1_22589737_ChIP-Seq_MCF10A_Human1.19278143
70SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.19206934
71KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.18160655
72KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.18160655
73KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.18160655
74KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.17439882
75ZNF263_19887448_ChIP-Seq_K562_Human1.17068850
76CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.15030966
77SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.11892647
78MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11300260
79KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10762576
80SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10583405
81BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09046888
82KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.07591305
83TFEB_21752829_ChIP-Seq_HELA_Human1.05255033
84KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04930536
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03761494
86ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02991108
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.02642460
88SOX17_20123909_ChIP-Seq_XEN_Mouse1.01672131
89EGR1_19374776_ChIP-ChIP_THP-1_Human1.01666394
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00094728
91MYC_18940864_ChIP-ChIP_HL60_Human0.99841789
92CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98961429
93PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.97763156
94DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97536171
95PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97062899
96SPI1_23547873_ChIP-Seq_NB4_Human0.96641840
97ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96619516
98CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.95855489
99CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94569813
100TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94442808
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93892539
102OCT4_18692474_ChIP-Seq_MEFs_Mouse0.93282286
103SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.92434709
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.89101792
105SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.88073145
106SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86232501
107TBX5_21415370_ChIP-Seq_HL-1_Mouse0.85664651
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85569487
109HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.84669158
110SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.84598734
111NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84491704
112* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84050426
113TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83057671
114VDR_21846776_ChIP-Seq_THP-1_Human0.82822948
115IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.80888902
116TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.80300261
117NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.80211281
118CTCF_18555785_ChIP-Seq_MESCs_Mouse0.78530640
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.78317580
120FOXP1_21924763_ChIP-Seq_HESCs_Human0.77985671
121ESR1_15608294_ChIP-ChIP_MCF-7_Human0.77701684

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.12593836
2MP0004957_abnormal_blastocyst_morpholog4.54815438
3MP0010094_abnormal_chromosome_stability3.90955435
4MP0003111_abnormal_nucleus_morphology3.76561261
5MP0008057_abnormal_DNA_replication3.71655012
6MP0003077_abnormal_cell_cycle3.66571367
7MP0008058_abnormal_DNA_repair3.00069127
8MP0002396_abnormal_hematopoietic_system2.55791984
9MP0008932_abnormal_embryonic_tissue2.54946031
10MP0008007_abnormal_cellular_replicative2.53479341
11MP0003123_paternal_imprinting2.51088421
12MP0003786_premature_aging2.10721845
13MP0009697_abnormal_copulation2.06251692
14MP0009379_abnormal_foot_pigmentation2.05022298
15MP0005408_hypopigmentation2.04869792
16MP0000490_abnormal_crypts_of2.01325765
17MP0001730_embryonic_growth_arrest1.94583430
18MP0000350_abnormal_cell_proliferation1.92647282
19MP0010352_gastrointestinal_tract_polyps1.90375961
20MP0009333_abnormal_splenocyte_physiolog1.73557026
21MP0003806_abnormal_nucleotide_metabolis1.64879834
22MP0003718_maternal_effect1.61346522
23MP0005075_abnormal_melanosome_morpholog1.59084411
24MP0002132_abnormal_respiratory_system1.57180075
25MP0003186_abnormal_redox_activity1.55261040
26MP0006292_abnormal_olfactory_placode1.55239797
27MP0001672_abnormal_embryogenesis/_devel1.54749017
28MP0005380_embryogenesis_phenotype1.54749017
29MP0005171_absent_coat_pigmentation1.51844758
30MP0001661_extended_life_span1.50117787
31MP0001697_abnormal_embryo_size1.47802332
32MP0010030_abnormal_orbit_morphology1.46357853
33MP0004808_abnormal_hematopoietic_stem1.45287224
34MP0003763_abnormal_thymus_physiology1.45076430
35MP0002877_abnormal_melanocyte_morpholog1.42733087
36MP0000313_abnormal_cell_death1.41140849
37MP0003984_embryonic_growth_retardation1.40273295
38MP0002019_abnormal_tumor_incidence1.39991404
39MP0002080_prenatal_lethality1.39233523
40MP0002088_abnormal_embryonic_growth/wei1.37790215
41MP0003121_genomic_imprinting1.32563990
42MP0003315_abnormal_perineum_morphology1.30189615
43MP0002085_abnormal_embryonic_tissue1.22475704
44MP0008877_abnormal_DNA_methylation1.19807380
45MP0002086_abnormal_extraembryonic_tissu1.17546497
46MP0003567_abnormal_fetal_cardiomyocyte1.14639430
47MP0005397_hematopoietic_system_phenotyp1.14521099
48MP0001545_abnormal_hematopoietic_system1.14521099
49MP0006035_abnormal_mitochondrial_morpho1.14378890
50MP0002234_abnormal_pharynx_morphology1.11601845
51MP0004233_abnormal_muscle_weight1.11466684
52MP0004147_increased_porphyrin_level1.10074492
53MP0006036_abnormal_mitochondrial_physio1.10034009
54MP0003890_abnormal_embryonic-extraembry1.09469589
55MP0003950_abnormal_plasma_membrane1.08753121
56MP0002722_abnormal_immune_system1.08574804
57MP0002398_abnormal_bone_marrow1.08060173
58MP0002084_abnormal_developmental_patter1.08050586
59MP0004197_abnormal_fetal_growth/weight/1.07739400
60MP0000689_abnormal_spleen_morphology1.05078492
61MP0006054_spinal_hemorrhage1.04197464
62MP0000358_abnormal_cell_content/1.04166921
63MP0001293_anophthalmia1.03916643
64MP0000703_abnormal_thymus_morphology1.03196280
65MP0004264_abnormal_extraembryonic_tissu1.00661750
66MP0001853_heart_inflammation0.97770782
67MP0001764_abnormal_homeostasis0.97356132
68MP0001881_abnormal_mammary_gland0.96554048
69MP0003937_abnormal_limbs/digits/tail_de0.96467046
70MP0000858_altered_metastatic_potential0.96041069
71MP0008995_early_reproductive_senescence0.95301384
72MP0000749_muscle_degeneration0.94977992
73MP0010307_abnormal_tumor_latency0.94347572
74MP0002429_abnormal_blood_cell0.93119465
75MP0003011_delayed_dark_adaptation0.93065265
76MP0001529_abnormal_vocalization0.91534152
77MP0002938_white_spotting0.88220481
78MP0001727_abnormal_embryo_implantation0.86561732
79MP0002210_abnormal_sex_determination0.85341882
80MP0005257_abnormal_intraocular_pressure0.83845482
81MP0008438_abnormal_cutaneous_collagen0.83360333
82MP0000750_abnormal_muscle_regeneration0.82425702
83MP0004272_abnormal_basement_membrane0.81845552
84MP0003941_abnormal_skin_development0.81406131
85MP0001145_abnormal_male_reproductive0.81210539
86MP0002102_abnormal_ear_morphology0.81157266
87MP0005023_abnormal_wound_healing0.81152066
88MP0001929_abnormal_gametogenesis0.79037666
89MP0005332_abnormal_amino_acid0.78826008
90MP0001835_abnormal_antigen_presentation0.78334530
91MP0009672_abnormal_birth_weight0.78063408
92MP0005330_cardiomyopathy0.77854665
93MP0000678_abnormal_parathyroid_gland0.77584464
94MP0005379_endocrine/exocrine_gland_phen0.76724556
95MP0000716_abnormal_immune_system0.76612032
96MP0002160_abnormal_reproductive_system0.76485444
97MP0004133_heterotaxia0.74899270
98MP0002277_abnormal_respiratory_mucosa0.74882322
99MP0000762_abnormal_tongue_morphology0.74381969
100MP0002697_abnormal_eye_size0.71938939
101MP0002163_abnormal_gland_morphology0.71813847
102MP0002060_abnormal_skin_morphology0.71342368
103MP0000537_abnormal_urethra_morphology0.71276966
104MP0002405_respiratory_system_inflammati0.70400267
105MP0001800_abnormal_humoral_immune0.69538539
106MP0005384_cellular_phenotype0.68733282
107MP0002111_abnormal_tail_morphology0.68648666
108MP0006072_abnormal_retinal_apoptosis0.68312705
109MP0001346_abnormal_lacrimal_gland0.68178630
110MP0000049_abnormal_middle_ear0.67890863
111MP0005266_abnormal_metabolism0.67546239
112MP0003119_abnormal_digestive_system0.67293850
113MP0003136_yellow_coat_color0.67164954
114MP0000647_abnormal_sebaceous_gland0.67080603
115MP0005501_abnormal_skin_physiology0.67012451
116MP0001119_abnormal_female_reproductive0.66599433
117MP0005671_abnormal_response_to0.66418917
118MP0003122_maternal_imprinting0.66270197
119MP0004381_abnormal_hair_follicle0.65382263
120MP0003755_abnormal_palate_morphology0.65046778
121MP0005394_taste/olfaction_phenotype0.64567167
122MP0005499_abnormal_olfactory_system0.64567167
123MP0009785_altered_susceptibility_to0.64025925
124MP0001186_pigmentation_phenotype0.63642234
125MP0000372_irregular_coat_pigmentation0.63199035
126MP0002233_abnormal_nose_morphology0.63188126
127MP0005395_other_phenotype0.62930761
128MP0005389_reproductive_system_phenotype0.62707375
129MP0000653_abnormal_sex_gland0.62522974
130MP0000477_abnormal_intestine_morphology0.62132783
131MP0008789_abnormal_olfactory_epithelium0.62100063
132MP0002177_abnormal_outer_ear0.61734408
133MP0002420_abnormal_adaptive_immunity0.61713136
134MP0002282_abnormal_trachea_morphology0.61522141
135MP0001243_abnormal_dermal_layer0.60537090
136MP0003436_decreased_susceptibility_to0.60326912
137MP0001819_abnormal_immune_cell0.60289326
138MP0002090_abnormal_vision0.59517853
139MP0002095_abnormal_skin_pigmentation0.59189529
140MP0002932_abnormal_joint_morphology0.59025959
141MP0001286_abnormal_eye_development0.58193714
142MP0003705_abnormal_hypodermis_morpholog0.57158579

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.36018522
2Abnormal number of erythroid precursors (HP:0012131)5.90487922
3Reticulocytopenia (HP:0001896)5.29281774
4Abnormal mitochondria in muscle tissue (HP:0008316)4.75411199
5Acute encephalopathy (HP:0006846)4.64224679
6Birth length less than 3rd percentile (HP:0003561)4.16353302
7Multiple enchondromatosis (HP:0005701)4.06434137
8Progressive macrocephaly (HP:0004481)3.94092372
9Macrocytic anemia (HP:0001972)3.90263920
10Pallor (HP:0000980)3.71709045
11Aplastic anemia (HP:0001915)3.55451955
12Oral leukoplakia (HP:0002745)3.53417012
13Cerebral edema (HP:0002181)3.52272403
14Cholecystitis (HP:0001082)3.32025346
15Abnormal gallbladder physiology (HP:0012438)3.32025346
16Trismus (HP:0000211)3.31610735
17Rough bone trabeculation (HP:0100670)3.17340131
18Aplasia/Hypoplasia of the sacrum (HP:0008517)3.13564973
19Breast hypoplasia (HP:0003187)3.12974437
20Selective tooth agenesis (HP:0001592)3.11766409
21Lactic acidosis (HP:0003128)3.11192174
22Microretrognathia (HP:0000308)3.05090515
23Chromsome breakage (HP:0040012)2.96395427
24Exercise intolerance (HP:0003546)2.89649879
25Colon cancer (HP:0003003)2.87606177
26Chromosomal breakage induced by crosslinking agents (HP:0003221)2.85747283
27Renal Fanconi syndrome (HP:0001994)2.80243103
28Respiratory failure (HP:0002878)2.80043025
29Carpal bone hypoplasia (HP:0001498)2.76651139
3011 pairs of ribs (HP:0000878)2.71814983
31Microvesicular hepatic steatosis (HP:0001414)2.70618164
32Thrombocytosis (HP:0001894)2.66950630
33Glossoptosis (HP:0000162)2.65948274
34Cerebral hypomyelination (HP:0006808)2.64285287
35Type I transferrin isoform profile (HP:0003642)2.63908551
36Degeneration of anterior horn cells (HP:0002398)2.63613365
37Abnormality of the anterior horn cell (HP:0006802)2.63613365
38Patellar aplasia (HP:0006443)2.61218963
39Abnormality of methionine metabolism (HP:0010901)2.61113751
40Increased intramyocellular lipid droplets (HP:0012240)2.60760525
41Abnormal lung lobation (HP:0002101)2.59949814
42Meckel diverticulum (HP:0002245)2.58677185
43Abnormal protein N-linked glycosylation (HP:0012347)2.56424032
44Abnormal protein glycosylation (HP:0012346)2.56424032
45Abnormal glycosylation (HP:0012345)2.56424032
46Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.56424032
473-Methylglutaconic aciduria (HP:0003535)2.55662048
48Abnormality of the preputium (HP:0100587)2.55041174
49Absent thumb (HP:0009777)2.53163008
50Decreased activity of mitochondrial respiratory chain (HP:0008972)2.47501908
51Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.47501908
52Aplasia/Hypoplasia of the patella (HP:0006498)2.46894473
53Secondary amenorrhea (HP:0000869)2.44743927
54Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.43364445
55Myelodysplasia (HP:0002863)2.42529961
56Abnormality of the ileum (HP:0001549)2.42349517
57Premature ovarian failure (HP:0008209)2.40259679
58Amniotic constriction ring (HP:0009775)2.39660984
59Abnormality of placental membranes (HP:0011409)2.39660984
60Rhabdomyosarcoma (HP:0002859)2.37971278
61Leukodystrophy (HP:0002415)2.34689713
62Sparse eyelashes (HP:0000653)2.34549540
63Abnormality of glycolysis (HP:0004366)2.31764704
64Increased serum pyruvate (HP:0003542)2.31764704
65Cleft eyelid (HP:0000625)2.31092908
66Premature graying of hair (HP:0002216)2.30478608
67Increased serum lactate (HP:0002151)2.26508640
68Abnormal trabecular bone morphology (HP:0100671)2.26501662
69Reduced antithrombin III activity (HP:0001976)2.21377556
70Increased hepatocellular lipid droplets (HP:0006565)2.21226188
71Bone marrow hypocellularity (HP:0005528)2.20700283
72Abnormalities of placenta or umbilical cord (HP:0001194)2.19023393
73Hepatocellular necrosis (HP:0001404)2.17433368
74Atresia of the external auditory canal (HP:0000413)2.16817229
75Medulloblastoma (HP:0002885)2.16638321
76Duodenal stenosis (HP:0100867)2.15085576
77Small intestinal stenosis (HP:0012848)2.15085576
78Pancytopenia (HP:0001876)2.14198263
79Aplasia/Hypoplasia of the uvula (HP:0010293)2.14164644
80Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.12821706
81Triphalangeal thumb (HP:0001199)2.11892556
82Testicular atrophy (HP:0000029)2.09939332
83Increased CSF lactate (HP:0002490)2.09609666
84Increased muscle lipid content (HP:0009058)2.08731697
85Facial cleft (HP:0002006)2.08677002
86Progressive muscle weakness (HP:0003323)2.08106822
87CNS demyelination (HP:0007305)2.08000453
88Supernumerary spleens (HP:0009799)2.07249680
89Abnormality of the heme biosynthetic pathway (HP:0010472)2.05505222
90Lethargy (HP:0001254)2.05260812
91Abnormality of chromosome stability (HP:0003220)2.04654940
92Ependymoma (HP:0002888)2.03912919
93Hypoplastic pelvis (HP:0008839)2.02433575
94Irregular epiphyses (HP:0010582)2.01474895
95Lipid accumulation in hepatocytes (HP:0006561)2.01164760
96Mitochondrial inheritance (HP:0001427)2.00990515
97Impulsivity (HP:0100710)1.99239441
98Abnormality of reticulocytes (HP:0004312)1.97551916
99Cellular immunodeficiency (HP:0005374)1.94864894
100Abnormal number of incisors (HP:0011064)1.94779678
101Abnormality of the fetal cardiovascular system (HP:0010948)1.94162439
102Abnormal umbilical cord blood vessels (HP:0011403)1.94162439
103Single umbilical artery (HP:0001195)1.94162439
104Squamous cell carcinoma (HP:0002860)1.94063600
105Optic disc pallor (HP:0000543)1.93776554
106Hepatic necrosis (HP:0002605)1.92361091
107Emotional lability (HP:0000712)1.92348749
108Sloping forehead (HP:0000340)1.92023810
109Neoplasm of the pancreas (HP:0002894)1.91771415
110Absent radius (HP:0003974)1.91651971
111Tracheoesophageal fistula (HP:0002575)1.91608333
112Redundant skin (HP:0001582)1.90987078
113Poor head control (HP:0002421)1.90856550
114Agnosia (HP:0010524)1.89564386
115Abnormality of aspartate family amino acid metabolism (HP:0010899)1.87267539
116Respiratory difficulties (HP:0002880)1.85681501
117Abnormality of the labia minora (HP:0012880)1.85000230
118Entropion (HP:0000621)1.84807099
119Missing ribs (HP:0000921)1.84703870
120Exertional dyspnea (HP:0002875)1.84081728
121Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.83962406
122Hypoplasia of the radius (HP:0002984)1.83861432
123Nephroblastoma (Wilms tumor) (HP:0002667)1.83694570
124Abnormality of the umbilical cord (HP:0010881)1.82745443
125Ragged-red muscle fibers (HP:0003200)1.82583017
126CNS hypomyelination (HP:0003429)1.82261038
127Horseshoe kidney (HP:0000085)1.80669944
128Abnormality of the duodenum (HP:0002246)1.78417562
129Acute necrotizing encephalopathy (HP:0006965)1.78334324
130IgM deficiency (HP:0002850)1.77565201
131Muscle fiber atrophy (HP:0100295)1.77269384
132Cutaneous melanoma (HP:0012056)1.77133634
133Neoplasm of the adrenal gland (HP:0100631)1.75550570
134Hypoplasia of the capital femoral epiphysis (HP:0003090)1.75264554
135Aplasia involving forearm bones (HP:0009822)1.75208940
136Absent forearm bone (HP:0003953)1.75208940
137Asplenia (HP:0001746)1.75204798
138Depressed nasal ridge (HP:0000457)1.74845436
139Cholelithiasis (HP:0001081)1.73824859
140Hypokinesia (HP:0002375)1.73604668
141Embryonal renal neoplasm (HP:0011794)1.72561373
142Upper limb muscle weakness (HP:0003484)1.71837078
143Bilateral microphthalmos (HP:0007633)1.71540589
144Reduced subcutaneous adipose tissue (HP:0003758)1.70564024
145Abnormality of sulfur amino acid metabolism (HP:0004339)1.69973635

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.62543080
2BUB14.52642184
3NME23.93754070
4WEE13.66482655
5EIF2AK13.20559514
6CDC72.91352082
7STK162.72095141
8EIF2AK32.37635207
9SRPK12.36995226
10NEK22.03541627
11TSSK62.03489456
12TTK2.02354497
13TLK11.91616613
14PIM21.89340215
15RPS6KB21.85552270
16VRK11.83440250
17PLK11.82441459
18PDK21.79131055
19CDK71.71421854
20BRSK21.70847982
21PASK1.69589660
22TRIM281.64226372
23SMG11.63943107
24ACVR1B1.61145097
25AURKB1.55877643
26MKNK11.55156263
27NEK11.52976230
28CDK121.52402427
29DYRK31.52231007
30TGFBR11.49780122
31PLK41.48516186
32BCKDK1.45635054
33TAF11.40039298
34NUAK11.37779448
35MAP3K121.37297295
36TESK21.34841992
37ERN11.33124236
38RPS6KA41.30949480
39PAK41.28957668
40STK101.27132369
41ATR1.24614183
42EPHA21.22418816
43CHEK21.20543404
44AURKA1.20442615
45EEF2K1.20216933
46MKNK21.18952213
47NME11.14505784
48LIMK11.13681658
49IRAK31.13535339
50CDK41.07727809
51MAP3K81.03634808
52LRRK21.01801360
53PLK31.01264213
54MAP4K11.00497454
55GRK60.98359269
56MST40.97616602
57MAP2K30.96606470
58CDK80.96572497
59BRSK10.92314122
60CHEK10.92215205
61DAPK10.92033305
62PIM10.89251414
63EIF2AK20.87399185
64MAP3K110.85761224
65CSF1R0.84825894
66BRAF0.83279636
67FLT30.82916414
68ZAK0.80757895
69CSNK1G30.79866535
70MAP3K100.79594041
71MAP3K30.76552556
72CCNB10.76549737
73ILK0.75813385
74MST1R0.75388891
75ERBB40.74713112
76PAK10.74627090
77CSNK2A10.73385563
78STK40.72920427
79CSNK2A20.72840883
80KDR0.71685459
81CLK10.70378053
82PRKCI0.69296545
83MAPKAPK50.69282922
84ZAP700.68413427
85SCYL20.65539177
86ADRBK20.64029281
87TAOK20.63817644
88CSNK1G10.63417986
89MAP2K60.62910111
90MAPKAPK30.61750694
91ARAF0.57603894
92CDK20.57097750
93ATM0.55783987
94CSNK1A1L0.55783005
95MATK0.53901582
96PKN20.53822283
97PBK0.52849026
98BTK0.52188169
99PLK20.51931111
100STK38L0.51653420
101MOS0.51577067
102RPS6KA50.48021569
103IKBKB0.47701828
104DAPK30.46097512
105ABL20.44214638
106GRK10.42437359
107CSNK1G20.42048599
108DYRK20.41822875
109KIT0.40761021
110BCR0.40513586
111TESK10.39999717
112STK240.39071930
113PRKG20.37870755
114MUSK0.37661259
115SIK30.37579153
116MAP4K20.36647600
117AKT20.35715979
118CDK10.35601678
119PIK3CG0.35403621
120CDK190.35190571
121MYLK0.34324792
122TEC0.34172489
123BLK0.31645696
124CDK180.31171073
125LMTK20.30843319
126CSNK1E0.30453107
127ALK0.30345715
128CDK90.30155787
129FER0.29167159
130GRK50.28809309
131BMPR1B0.28440464
132CDK140.28282807
133CDK11A0.28244441
134FGFR10.26774990
135CDK150.25793472

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.27789679
2DNA replication_Homo sapiens_hsa030304.37079631
3Proteasome_Homo sapiens_hsa030503.96011502
4Mismatch repair_Homo sapiens_hsa034303.72033560
5RNA polymerase_Homo sapiens_hsa030203.57680127
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.56611032
7Spliceosome_Homo sapiens_hsa030402.94121158
8Base excision repair_Homo sapiens_hsa034102.77956572
9* RNA transport_Homo sapiens_hsa030132.73342432
10Homologous recombination_Homo sapiens_hsa034402.63727002
11Pyrimidine metabolism_Homo sapiens_hsa002402.60122048
12Nucleotide excision repair_Homo sapiens_hsa034202.56169096
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.31393100
14One carbon pool by folate_Homo sapiens_hsa006702.17839142
15Cell cycle_Homo sapiens_hsa041102.09335278
16RNA degradation_Homo sapiens_hsa030181.78970715
17Fanconi anemia pathway_Homo sapiens_hsa034601.74257790
18Basal transcription factors_Homo sapiens_hsa030221.72844703
19Non-homologous end-joining_Homo sapiens_hsa034501.71601082
20Pyruvate metabolism_Homo sapiens_hsa006201.61960040
21Fatty acid elongation_Homo sapiens_hsa000621.53177375
22Protein export_Homo sapiens_hsa030601.48986317
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42053819
24Purine metabolism_Homo sapiens_hsa002301.30890230
25Parkinsons disease_Homo sapiens_hsa050121.29639114
26mRNA surveillance pathway_Homo sapiens_hsa030151.28418239
27p53 signaling pathway_Homo sapiens_hsa041151.27630964
28Vitamin B6 metabolism_Homo sapiens_hsa007501.27009888
29Oxidative phosphorylation_Homo sapiens_hsa001901.24689391
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.21341627
31Propanoate metabolism_Homo sapiens_hsa006401.20438667
32Sulfur metabolism_Homo sapiens_hsa009201.18398303
33Folate biosynthesis_Homo sapiens_hsa007901.13145484
34Huntingtons disease_Homo sapiens_hsa050161.12762801
35Epstein-Barr virus infection_Homo sapiens_hsa051691.04413570
36Steroid biosynthesis_Homo sapiens_hsa001001.02306131
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01034116
38Pentose phosphate pathway_Homo sapiens_hsa000300.97167572
39Sulfur relay system_Homo sapiens_hsa041220.92346225
40Cysteine and methionine metabolism_Homo sapiens_hsa002700.91420127
41Drug metabolism - other enzymes_Homo sapiens_hsa009830.87346789
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87111811
43Biosynthesis of amino acids_Homo sapiens_hsa012300.85194817
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81674810
45Systemic lupus erythematosus_Homo sapiens_hsa053220.81577431
46Herpes simplex infection_Homo sapiens_hsa051680.80639792
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80377052
48Fructose and mannose metabolism_Homo sapiens_hsa000510.77062891
49Antigen processing and presentation_Homo sapiens_hsa046120.74990369
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73176830
51Glutathione metabolism_Homo sapiens_hsa004800.71635939
52Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.69270392
53Galactose metabolism_Homo sapiens_hsa000520.65216343
54Arachidonic acid metabolism_Homo sapiens_hsa005900.64748897
55Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64493520
56Cardiac muscle contraction_Homo sapiens_hsa042600.63463901
57Cyanoamino acid metabolism_Homo sapiens_hsa004600.63406854
58Legionellosis_Homo sapiens_hsa051340.63252645
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61451175
60Carbon metabolism_Homo sapiens_hsa012000.60460576
61Thyroid cancer_Homo sapiens_hsa052160.60334727
62Viral carcinogenesis_Homo sapiens_hsa052030.59274074
632-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58524384
64Primary immunodeficiency_Homo sapiens_hsa053400.58492594
65Alzheimers disease_Homo sapiens_hsa050100.57785277
66Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56516611
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53267372
68Fatty acid metabolism_Homo sapiens_hsa012120.50570884
69HTLV-I infection_Homo sapiens_hsa051660.50471973
70Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50035200
71Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48696215
72Selenocompound metabolism_Homo sapiens_hsa004500.48675482
73Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46562693
74Vibrio cholerae infection_Homo sapiens_hsa051100.45527535
75Peroxisome_Homo sapiens_hsa041460.44564617
76Metabolic pathways_Homo sapiens_hsa011000.43192354
77Apoptosis_Homo sapiens_hsa042100.39955658
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38497271
79Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37357105
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36706404
81Oocyte meiosis_Homo sapiens_hsa041140.36260688
82N-Glycan biosynthesis_Homo sapiens_hsa005100.36084262
83Tyrosine metabolism_Homo sapiens_hsa003500.32651962
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31198495
85Measles_Homo sapiens_hsa051620.31098408
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.30736818
87Linoleic acid metabolism_Homo sapiens_hsa005910.28845915
88NF-kappa B signaling pathway_Homo sapiens_hsa040640.27991665
89Small cell lung cancer_Homo sapiens_hsa052220.27883238
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.27735687
91Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27603673
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26590716
93beta-Alanine metabolism_Homo sapiens_hsa004100.26104455
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.25779982
95Fatty acid degradation_Homo sapiens_hsa000710.25604640
96Arginine biosynthesis_Homo sapiens_hsa002200.24952186
97Butanoate metabolism_Homo sapiens_hsa006500.24750027
98Regulation of autophagy_Homo sapiens_hsa041400.24543652
99Caffeine metabolism_Homo sapiens_hsa002320.24386625
100Hematopoietic cell lineage_Homo sapiens_hsa046400.23113660
101Other glycan degradation_Homo sapiens_hsa005110.21540502
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19140638
103MicroRNAs in cancer_Homo sapiens_hsa052060.19095192
104Influenza A_Homo sapiens_hsa051640.18810960
105Bladder cancer_Homo sapiens_hsa052190.17641242
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.16857573
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.16753947
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16517199
109Basal cell carcinoma_Homo sapiens_hsa052170.16451928
110Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.16377929
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.16184068
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.15963598
113Shigellosis_Homo sapiens_hsa051310.15898063
114Allograft rejection_Homo sapiens_hsa053300.15272426
115Acute myeloid leukemia_Homo sapiens_hsa052210.15039168
116TGF-beta signaling pathway_Homo sapiens_hsa043500.14827814
117Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.14742217
118Central carbon metabolism in cancer_Homo sapiens_hsa052300.14662352
119Asthma_Homo sapiens_hsa053100.14181128
120Hepatitis B_Homo sapiens_hsa051610.14128613
121Vitamin digestion and absorption_Homo sapiens_hsa049770.13989840
122alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.13147204
123Phenylalanine metabolism_Homo sapiens_hsa003600.12868907
124HIF-1 signaling pathway_Homo sapiens_hsa040660.12234189
125Arginine and proline metabolism_Homo sapiens_hsa003300.10949856
126Collecting duct acid secretion_Homo sapiens_hsa049660.08578520
127Tryptophan metabolism_Homo sapiens_hsa003800.07943986
128Fat digestion and absorption_Homo sapiens_hsa049750.07332101
129Lysine degradation_Homo sapiens_hsa003100.06770900
130Alcoholism_Homo sapiens_hsa050340.01927255

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