

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.70956274 |
| 2 | L-fucose catabolic process (GO:0042355) | 4.75820382 |
| 3 | fucose catabolic process (GO:0019317) | 4.75820382 |
| 4 | L-fucose metabolic process (GO:0042354) | 4.75820382 |
| 5 | proteasome assembly (GO:0043248) | 4.16223884 |
| 6 | platelet dense granule organization (GO:0060155) | 4.04614571 |
| 7 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 4.01110322 |
| 8 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 3.92983461 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 3.79452907 |
| 10 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.76316446 |
| 11 | maturation of 5.8S rRNA (GO:0000460) | 3.74956017 |
| 12 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.74360172 |
| 13 | isotype switching (GO:0045190) | 3.74360172 |
| 14 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.74360172 |
| 15 | cellular response to ATP (GO:0071318) | 3.72021653 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.70337437 |
| 17 | cullin deneddylation (GO:0010388) | 3.68409854 |
| 18 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.67229604 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.67229604 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.67229604 |
| 21 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.66071799 |
| 22 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.59810693 |
| 23 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.59070857 |
| 24 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.59070857 |
| 25 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.59070857 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.58945173 |
| 27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.54628032 |
| 28 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.54628032 |
| 29 | chaperone-mediated protein transport (GO:0072321) | 3.51865934 |
| 30 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.49056363 |
| 31 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.47581459 |
| 32 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.45846999 |
| 33 | ATP synthesis coupled proton transport (GO:0015986) | 3.45846999 |
| 34 | base-excision repair, AP site formation (GO:0006285) | 3.45618540 |
| 35 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.44842443 |
| 36 | protein deneddylation (GO:0000338) | 3.41941697 |
| 37 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.39148138 |
| 38 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.39148138 |
| 39 | regulation of immunoglobulin secretion (GO:0051023) | 3.37499368 |
| 40 | negative regulation of B cell apoptotic process (GO:0002903) | 3.37216594 |
| 41 | aldehyde catabolic process (GO:0046185) | 3.37169471 |
| 42 | protein complex biogenesis (GO:0070271) | 3.36408711 |
| 43 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.34474508 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.32952073 |
| 45 | high-density lipoprotein particle remodeling (GO:0034375) | 3.30600122 |
| 46 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.29868743 |
| 47 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.29705297 |
| 48 | response to pheromone (GO:0019236) | 3.26459662 |
| 49 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.24795085 |
| 50 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.21049012 |
| 51 | regulation of cholesterol esterification (GO:0010872) | 3.19468483 |
| 52 | dolichol-linked oligosaccharide biosynthetic process (GO:0006488) | 3.17704561 |
| 53 | rRNA catabolic process (GO:0016075) | 3.16183779 |
| 54 | plasma membrane fusion (GO:0045026) | 3.15386413 |
| 55 | cytidine metabolic process (GO:0046087) | 3.12294050 |
| 56 | cytidine catabolic process (GO:0006216) | 3.12294050 |
| 57 | cytidine deamination (GO:0009972) | 3.12294050 |
| 58 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.06104571 |
| 59 | negative regulation of ligase activity (GO:0051352) | 3.06104571 |
| 60 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.05426850 |
| 61 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.03077837 |
| 62 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.00122446 |
| 63 | regulation of regulatory T cell differentiation (GO:0045589) | 2.98448456 |
| 64 | regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) | 2.98330543 |
| 65 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.96056086 |
| 66 | positive regulation of interleukin-17 production (GO:0032740) | 2.95118480 |
| 67 | reverse cholesterol transport (GO:0043691) | 2.92273249 |
| 68 | phospholipid homeostasis (GO:0055091) | 2.90999759 |
| 69 | regulation of heterotypic cell-cell adhesion (GO:0034114) | 2.90915110 |
| 70 | electron transport chain (GO:0022900) | 2.89205795 |
| 71 | respiratory electron transport chain (GO:0022904) | 2.88317533 |
| 72 | negative regulation of interleukin-1 beta production (GO:0032691) | 2.87915489 |
| 73 | pseudouridine synthesis (GO:0001522) | 2.86924658 |
| 74 | amine catabolic process (GO:0009310) | 2.84645914 |
| 75 | cellular biogenic amine catabolic process (GO:0042402) | 2.84645914 |
| 76 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.84343822 |
| 77 | signal peptide processing (GO:0006465) | 2.83448091 |
| 78 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.83290298 |
| 79 | termination of RNA polymerase III transcription (GO:0006386) | 2.79875790 |
| 80 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.79875790 |
| 81 | mannosylation (GO:0097502) | 2.79197566 |
| 82 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.78988888 |
| 83 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.75808914 |
| 84 | positive regulation of cell cycle arrest (GO:0071158) | 2.75791051 |
| 85 | nucleotide transmembrane transport (GO:1901679) | 2.70992228 |
| 86 | protein neddylation (GO:0045116) | 2.69978513 |
| 87 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.68761327 |
| 88 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.68126994 |
| 89 | rRNA modification (GO:0000154) | 2.65969786 |
| 90 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.65448172 |
| 91 | GDP-mannose metabolic process (GO:0019673) | 2.64384926 |
| 92 | xenobiotic catabolic process (GO:0042178) | 2.62982054 |
| 93 | positive regulation of ligase activity (GO:0051351) | 2.61356522 |
| 94 | detection of light stimulus involved in visual perception (GO:0050908) | 2.60353763 |
| 95 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.60353763 |
| 96 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.54250495 |
| 97 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.53767714 |
| 98 | regulation of cellular amine metabolic process (GO:0033238) | 2.53699322 |
| 99 | ADP metabolic process (GO:0046031) | 2.52087136 |
| 100 | positive regulation of isotype switching (GO:0045830) | 2.50158961 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.69780718 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.89567693 |
| 3 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.38219590 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.18285633 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.18220648 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.78175913 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.75488308 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.53977053 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.44040498 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.41341759 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.37163153 |
| 12 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.31257927 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.26884739 |
| 14 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.25485933 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.22437061 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21559057 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.19602870 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.08931173 |
| 19 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.08373049 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07744306 |
| 21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.06181066 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.04142367 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.97807872 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.94308527 |
| 25 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.94273237 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.91355329 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.88096102 |
| 28 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.84952654 |
| 29 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.82349023 |
| 30 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.79051931 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.75397725 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71383297 |
| 33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.70957402 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.66163727 |
| 35 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.60298492 |
| 36 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.55619047 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55311646 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.54099997 |
| 39 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.48944855 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44401963 |
| 41 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43482760 |
| 42 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.38534409 |
| 43 | AR_20517297_ChIP-Seq_VCAP_Human | 1.37427826 |
| 44 | GATA3_26560356_Chip-Seq_TH2_Human | 1.37389036 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.36352552 |
| 46 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.36103980 |
| 47 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33668338 |
| 48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.33179076 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.32061006 |
| 50 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.30114170 |
| 51 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29431958 |
| 52 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29431958 |
| 53 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.29199441 |
| 54 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.28339988 |
| 55 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27658374 |
| 56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27658374 |
| 57 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26238009 |
| 58 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23000338 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.22393766 |
| 60 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.22000230 |
| 61 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.21030961 |
| 62 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18926479 |
| 63 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.17181866 |
| 64 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.17090552 |
| 65 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.17079817 |
| 66 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.16084278 |
| 67 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.15076919 |
| 68 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.12512646 |
| 69 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.12278123 |
| 70 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.11813277 |
| 71 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.08743729 |
| 72 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08110220 |
| 73 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.04725576 |
| 74 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04090250 |
| 75 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.03268819 |
| 76 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.03030511 |
| 77 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.02879059 |
| 78 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01223577 |
| 79 | * ER_23166858_ChIP-Seq_MCF-7_Human | 0.99855322 |
| 80 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99274126 |
| 81 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.98593817 |
| 82 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.97096138 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96955667 |
| 84 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96423436 |
| 85 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96364724 |
| 86 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.96129935 |
| 87 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95184338 |
| 88 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.94122098 |
| 89 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.94034633 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.93310667 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93310667 |
| 92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91434824 |
| 93 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.90659601 |
| 94 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.90213219 |
| 95 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.88932344 |
| 96 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88212151 |
| 97 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.87785692 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.85719385 |
| 99 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.84807619 |
| 100 | * TAF2_19829295_ChIP-Seq_ESCs_Human | 0.84625326 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008004_abnormal_stomach_pH | 3.68367561 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 3.51973530 |
| 3 | MP0004147_increased_porphyrin_level | 3.49176871 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.99301069 |
| 5 | MP0002736_abnormal_nociception_after | 2.94738041 |
| 6 | MP0008872_abnormal_physiological_respon | 2.86226062 |
| 7 | MP0005085_abnormal_gallbladder_physiolo | 2.72150516 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.66765762 |
| 9 | MP0005671_abnormal_response_to | 2.66581211 |
| 10 | MP0006054_spinal_hemorrhage | 2.60184401 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.47725076 |
| 12 | MP0002006_tumorigenesis | 2.31079665 |
| 13 | MP0009840_abnormal_foam_cell | 2.23902472 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.22389808 |
| 15 | MP0003300_gastrointestinal_ulcer | 2.21929890 |
| 16 | MP0001968_abnormal_touch/_nociception | 2.16439757 |
| 17 | MP0000465_gastrointestinal_hemorrhage | 2.13292338 |
| 18 | MP0003693_abnormal_embryo_hatching | 2.07081455 |
| 19 | MP0001986_abnormal_taste_sensitivity | 1.98452841 |
| 20 | MP0005365_abnormal_bile_salt | 1.91545150 |
| 21 | MP0004142_abnormal_muscle_tone | 1.88627128 |
| 22 | MP0002166_altered_tumor_susceptibility | 1.86131881 |
| 23 | MP0003045_fibrosis | 1.81710197 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 1.81193588 |
| 25 | MP0004885_abnormal_endolymph | 1.80776844 |
| 26 | MP0005464_abnormal_platelet_physiology | 1.78009658 |
| 27 | MP0003186_abnormal_redox_activity | 1.77850769 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.74473819 |
| 29 | MP0009785_altered_susceptibility_to | 1.73817044 |
| 30 | MP0003252_abnormal_bile_duct | 1.70077602 |
| 31 | MP0002102_abnormal_ear_morphology | 1.65655959 |
| 32 | MP0006036_abnormal_mitochondrial_physio | 1.63314565 |
| 33 | MP0003195_calcinosis | 1.54151599 |
| 34 | MP0001790_abnormal_immune_system | 1.53534100 |
| 35 | MP0005387_immune_system_phenotype | 1.53534100 |
| 36 | MP0010329_abnormal_lipoprotein_level | 1.51444017 |
| 37 | MP0006072_abnormal_retinal_apoptosis | 1.48155430 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.43792712 |
| 39 | MP0005075_abnormal_melanosome_morpholog | 1.41556808 |
| 40 | MP0005636_abnormal_mineral_homeostasis | 1.41259220 |
| 41 | MP0003724_increased_susceptibility_to | 1.38806268 |
| 42 | MP0002139_abnormal_hepatobiliary_system | 1.36674741 |
| 43 | MP0001800_abnormal_humoral_immune | 1.36317563 |
| 44 | MP0009764_decreased_sensitivity_to | 1.34240819 |
| 45 | MP0001853_heart_inflammation | 1.32467303 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.31681013 |
| 47 | MP0000685_abnormal_immune_system | 1.29527488 |
| 48 | MP0003011_delayed_dark_adaptation | 1.27100297 |
| 49 | MP0001666_abnormal_nutrient_absorption | 1.25764684 |
| 50 | MP0001664_abnormal_digestion | 1.25000791 |
| 51 | MP0003191_abnormal_cellular_cholesterol | 1.24503916 |
| 52 | MP0005084_abnormal_gallbladder_morpholo | 1.22895452 |
| 53 | MP0005000_abnormal_immune_tolerance | 1.22643675 |
| 54 | MP0001529_abnormal_vocalization | 1.20268356 |
| 55 | MP0003718_maternal_effect | 1.16841262 |
| 56 | MP0001764_abnormal_homeostasis | 1.14337681 |
| 57 | MP0005332_abnormal_amino_acid | 1.12866732 |
| 58 | MP0009333_abnormal_splenocyte_physiolog | 1.12496994 |
| 59 | MP0005410_abnormal_fertilization | 1.11519855 |
| 60 | MP0005083_abnormal_biliary_tract | 1.11459789 |
| 61 | MP0008058_abnormal_DNA_repair | 1.09122726 |
| 62 | MP0009697_abnormal_copulation | 1.08354996 |
| 63 | MP0002837_dystrophic_cardiac_calcinosis | 1.07054135 |
| 64 | MP0002452_abnormal_antigen_presenting | 1.06592558 |
| 65 | MP0002876_abnormal_thyroid_physiology | 1.02898680 |
| 66 | MP0002723_abnormal_immune_serum | 1.02447480 |
| 67 | MP0005253_abnormal_eye_physiology | 0.98701812 |
| 68 | MP0001919_abnormal_reproductive_system | 0.97756130 |
| 69 | MP0000230_abnormal_systemic_arterial | 0.92122083 |
| 70 | MP0005646_abnormal_pituitary_gland | 0.91434409 |
| 71 | MP0005551_abnormal_eye_electrophysiolog | 0.91216822 |
| 72 | MP0006276_abnormal_autonomic_nervous | 0.91206181 |
| 73 | MP0002420_abnormal_adaptive_immunity | 0.88055350 |
| 74 | MP0003646_muscle_fatigue | 0.87617203 |
| 75 | MP0010155_abnormal_intestine_physiology | 0.87609274 |
| 76 | MP0001819_abnormal_immune_cell | 0.86278453 |
| 77 | MP0001440_abnormal_grooming_behavior | 0.85786439 |
| 78 | MP0003763_abnormal_thymus_physiology | 0.85551357 |
| 79 | MP0000639_abnormal_adrenal_gland | 0.85143657 |
| 80 | MP0009046_muscle_twitch | 0.82468549 |
| 81 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.82464879 |
| 82 | MP0004957_abnormal_blastocyst_morpholog | 0.82313887 |
| 83 | MP0001873_stomach_inflammation | 0.82277383 |
| 84 | MP0004019_abnormal_vitamin_homeostasis | 0.80751767 |
| 85 | MP0001845_abnormal_inflammatory_respons | 0.80311879 |
| 86 | MP0005379_endocrine/exocrine_gland_phen | 0.80117926 |
| 87 | MP0001663_abnormal_digestive_system | 0.77677679 |
| 88 | MP0003436_decreased_susceptibility_to | 0.76338802 |
| 89 | MP0005025_abnormal_response_to | 0.75575794 |
| 90 | MP0002405_respiratory_system_inflammati | 0.75523576 |
| 91 | MP0002272_abnormal_nervous_system | 0.74439179 |
| 92 | MP0001970_abnormal_pain_threshold | 0.74048422 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.71988808 |
| 94 | MP0005389_reproductive_system_phenotype | 0.71593177 |
| 95 | MP0008877_abnormal_DNA_methylation | 0.71559059 |
| 96 | MP0000689_abnormal_spleen_morphology | 0.70399752 |
| 97 | MP0005535_abnormal_body_temperature | 0.69394143 |
| 98 | MP0000470_abnormal_stomach_morphology | 0.68748009 |
| 99 | MP0005395_other_phenotype | 0.67420695 |
| 100 | MP0001765_abnormal_ion_homeostasis | 0.67101448 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.00036450 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.67904438 |
| 3 | Acute encephalopathy (HP:0006846) | 4.62871113 |
| 4 | Type I transferrin isoform profile (HP:0003642) | 4.38371714 |
| 5 | Hypoproteinemia (HP:0003075) | 4.36333453 |
| 6 | Reduced antithrombin III activity (HP:0001976) | 4.26285301 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.19777277 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.80533510 |
| 9 | Increased CSF lactate (HP:0002490) | 3.70579245 |
| 10 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.47906547 |
| 11 | Abnormal protein glycosylation (HP:0012346) | 3.47906547 |
| 12 | Abnormal glycosylation (HP:0012345) | 3.47906547 |
| 13 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.47906547 |
| 14 | Stomatitis (HP:0010280) | 3.43396551 |
| 15 | Cerebral edema (HP:0002181) | 3.42075127 |
| 16 | Hepatocellular necrosis (HP:0001404) | 3.41173642 |
| 17 | Hepatic necrosis (HP:0002605) | 3.29435838 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.23082335 |
| 19 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.23082335 |
| 20 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.22877504 |
| 21 | Hypomagnesemia (HP:0002917) | 3.11813930 |
| 22 | Increased serum lactate (HP:0002151) | 2.97529062 |
| 23 | Spontaneous abortion (HP:0005268) | 2.78781799 |
| 24 | Abnormality of the pons (HP:0007361) | 2.68945645 |
| 25 | Hypoplasia of the pons (HP:0012110) | 2.64780100 |
| 26 | Decreased central vision (HP:0007663) | 2.63363422 |
| 27 | Increased intramyocellular lipid droplets (HP:0012240) | 2.63094475 |
| 28 | 3-Methylglutaconic aciduria (HP:0003535) | 2.62342463 |
| 29 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.55390243 |
| 30 | Lactic acidosis (HP:0003128) | 2.55165446 |
| 31 | Chronic hepatic failure (HP:0100626) | 2.53047546 |
| 32 | Abnormality of magnesium homeostasis (HP:0004921) | 2.52715524 |
| 33 | Exercise intolerance (HP:0003546) | 2.52379327 |
| 34 | Abnormality of DNA repair (HP:0003254) | 2.49128967 |
| 35 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.44935498 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.42182303 |
| 37 | Petechiae (HP:0000967) | 2.42134176 |
| 38 | Respiratory failure (HP:0002878) | 2.40417499 |
| 39 | Delayed CNS myelination (HP:0002188) | 2.37880908 |
| 40 | Increased hepatocellular lipid droplets (HP:0006565) | 2.37040532 |
| 41 | Abnormality of the prostate (HP:0008775) | 2.36614992 |
| 42 | CNS demyelination (HP:0007305) | 2.35569967 |
| 43 | Optic disc pallor (HP:0000543) | 2.35298451 |
| 44 | Hypothermia (HP:0002045) | 2.34553259 |
| 45 | IgG deficiency (HP:0004315) | 2.28143776 |
| 46 | Congenital, generalized hypertrichosis (HP:0004540) | 2.24282722 |
| 47 | Facial diplegia (HP:0001349) | 2.24155405 |
| 48 | Leukodystrophy (HP:0002415) | 2.23055869 |
| 49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.22031594 |
| 50 | Intrahepatic cholestasis (HP:0001406) | 2.19511039 |
| 51 | Lethargy (HP:0001254) | 2.16767805 |
| 52 | Abnormality of midbrain morphology (HP:0002418) | 2.13629973 |
| 53 | Molar tooth sign on MRI (HP:0002419) | 2.13629973 |
| 54 | Increased muscle lipid content (HP:0009058) | 2.12375270 |
| 55 | Meckel diverticulum (HP:0002245) | 2.08315698 |
| 56 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.07958002 |
| 57 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.05064683 |
| 58 | Abolished electroretinogram (ERG) (HP:0000550) | 2.05058525 |
| 59 | Abnormality of the renal cortex (HP:0011035) | 2.02843400 |
| 60 | Abnormality of the ileum (HP:0001549) | 2.02663070 |
| 61 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.01918544 |
| 62 | Constricted visual fields (HP:0001133) | 1.99779393 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.97532331 |
| 64 | Testicular atrophy (HP:0000029) | 1.96897657 |
| 65 | Poor head control (HP:0002421) | 1.96138092 |
| 66 | Type 2 muscle fiber atrophy (HP:0003554) | 1.95161024 |
| 67 | Duplicated collecting system (HP:0000081) | 1.94835394 |
| 68 | Concave nail (HP:0001598) | 1.94580572 |
| 69 | Abnormality of the renal collecting system (HP:0004742) | 1.94359673 |
| 70 | Renal cortical cysts (HP:0000803) | 1.92849540 |
| 71 | Abnormality of T cell physiology (HP:0011840) | 1.92070964 |
| 72 | Prostate neoplasm (HP:0100787) | 1.91011767 |
| 73 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.89102298 |
| 74 | Progressive inability to walk (HP:0002505) | 1.88815545 |
| 75 | Microvesicular hepatic steatosis (HP:0001414) | 1.87496107 |
| 76 | Exertional dyspnea (HP:0002875) | 1.87415110 |
| 77 | Skin rash (HP:0000988) | 1.86443305 |
| 78 | Clubbing of toes (HP:0100760) | 1.85760240 |
| 79 | Methylmalonic acidemia (HP:0002912) | 1.85361002 |
| 80 | Amyloidosis (HP:0011034) | 1.85068229 |
| 81 | Methylmalonic aciduria (HP:0012120) | 1.84315227 |
| 82 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.83842023 |
| 83 | Hypoplasia of the uterus (HP:0000013) | 1.83786255 |
| 84 | Arthropathy (HP:0003040) | 1.81633940 |
| 85 | Stomach cancer (HP:0012126) | 1.80475162 |
| 86 | Pancreatic cysts (HP:0001737) | 1.79969585 |
| 87 | Autoimmune hemolytic anemia (HP:0001890) | 1.79617043 |
| 88 | Palpitations (HP:0001962) | 1.78206841 |
| 89 | Nephronophthisis (HP:0000090) | 1.76680422 |
| 90 | Congenital stationary night blindness (HP:0007642) | 1.72593351 |
| 91 | Bile duct proliferation (HP:0001408) | 1.71696379 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 1.71696379 |
| 93 | Abnormality of the renal medulla (HP:0100957) | 1.71010541 |
| 94 | Abnormality of urine glucose concentration (HP:0011016) | 1.70354858 |
| 95 | Glycosuria (HP:0003076) | 1.70354858 |
| 96 | Keratoconus (HP:0000563) | 1.69932985 |
| 97 | Increased corneal curvature (HP:0100692) | 1.69932985 |
| 98 | Abnormality of the preputium (HP:0100587) | 1.68978432 |
| 99 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.68677400 |
| 100 | Abnormality of methionine metabolism (HP:0010901) | 1.68131546 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 5.00615396 |
| 2 | EIF2AK1 | 3.95166477 |
| 3 | BCKDK | 2.81491608 |
| 4 | TSSK6 | 2.60178482 |
| 5 | NUAK1 | 2.57510223 |
| 6 | PDK2 | 2.50604908 |
| 7 | TLK1 | 2.49369621 |
| 8 | ZAK | 2.44705435 |
| 9 | VRK2 | 2.43465483 |
| 10 | GRK1 | 2.39345757 |
| 11 | FRK | 2.12392990 |
| 12 | FER | 2.06617916 |
| 13 | EIF2AK3 | 2.03671095 |
| 14 | TAOK3 | 1.99433128 |
| 15 | TEC | 1.98324633 |
| 16 | ADRBK2 | 1.89023929 |
| 17 | ITK | 1.81473221 |
| 18 | FES | 1.78714222 |
| 19 | KIT | 1.77991122 |
| 20 | NEK9 | 1.66756129 |
| 21 | PLK2 | 1.62357667 |
| 22 | MAP3K12 | 1.61722862 |
| 23 | FLT3 | 1.55034857 |
| 24 | NME1 | 1.44280529 |
| 25 | PINK1 | 1.41562384 |
| 26 | PHKG1 | 1.39551416 |
| 27 | PHKG2 | 1.39551416 |
| 28 | KDR | 1.37996049 |
| 29 | OXSR1 | 1.35910739 |
| 30 | MAP4K2 | 1.34666932 |
| 31 | PLK3 | 1.33640310 |
| 32 | STK16 | 1.30832917 |
| 33 | LMTK2 | 1.26594517 |
| 34 | TXK | 1.22359798 |
| 35 | CDK19 | 1.18413498 |
| 36 | PRKCE | 1.14605874 |
| 37 | MYLK | 1.11908154 |
| 38 | TAF1 | 1.11026222 |
| 39 | SRPK1 | 1.10378999 |
| 40 | SYK | 1.08882617 |
| 41 | ZAP70 | 1.03063520 |
| 42 | STK39 | 1.01135930 |
| 43 | WNK4 | 0.92135348 |
| 44 | ALK | 0.91971416 |
| 45 | TIE1 | 0.90321891 |
| 46 | WNK3 | 0.86654443 |
| 47 | MAP2K6 | 0.84691328 |
| 48 | VRK1 | 0.82295915 |
| 49 | GRK6 | 0.81279923 |
| 50 | IKBKE | 0.80716933 |
| 51 | BMPR2 | 0.79152193 |
| 52 | STK38L | 0.76482119 |
| 53 | INSRR | 0.76352516 |
| 54 | IKBKB | 0.75714656 |
| 55 | PIM2 | 0.73044871 |
| 56 | GRK5 | 0.72416524 |
| 57 | BUB1 | 0.71141337 |
| 58 | PRKCI | 0.71079066 |
| 59 | DYRK2 | 0.70624456 |
| 60 | DAPK1 | 0.68136470 |
| 61 | CSNK1G3 | 0.67202913 |
| 62 | NEK1 | 0.65575828 |
| 63 | MAPKAPK3 | 0.64886707 |
| 64 | CCNB1 | 0.64385062 |
| 65 | PAK4 | 0.63099028 |
| 66 | STK24 | 0.61796049 |
| 67 | CSNK1A1 | 0.61163613 |
| 68 | BMPR1B | 0.59651877 |
| 69 | LYN | 0.59218669 |
| 70 | ERBB3 | 0.56314121 |
| 71 | CSNK1G1 | 0.50777569 |
| 72 | EIF2AK2 | 0.50434835 |
| 73 | PIM1 | 0.50108783 |
| 74 | ATR | 0.48485344 |
| 75 | CDK8 | 0.48210739 |
| 76 | CSNK1G2 | 0.47260443 |
| 77 | CSF1R | 0.45796762 |
| 78 | CSNK1A1L | 0.45456662 |
| 79 | PLK1 | 0.45332453 |
| 80 | DAPK2 | 0.44505990 |
| 81 | ADRBK1 | 0.43688992 |
| 82 | ILK | 0.43675603 |
| 83 | PRKCA | 0.43603789 |
| 84 | PLK4 | 0.42404213 |
| 85 | PTK2B | 0.40113872 |
| 86 | PRKACA | 0.38562575 |
| 87 | CSNK2A1 | 0.37322281 |
| 88 | LCK | 0.37133596 |
| 89 | ABL2 | 0.36130095 |
| 90 | RPS6KA5 | 0.35635481 |
| 91 | IGF1R | 0.34551109 |
| 92 | JAK3 | 0.32590010 |
| 93 | PRKG2 | 0.31222628 |
| 94 | MAPKAPK5 | 0.30650420 |
| 95 | ACVR1B | 0.29478172 |
| 96 | PRKCG | 0.28724254 |
| 97 | OBSCN | 0.28658835 |
| 98 | MAP4K1 | 0.28541241 |
| 99 | MAPK13 | 0.27929237 |
| 100 | CAMK2A | 0.27645590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.25732120 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.83479708 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.55812774 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.34919122 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.16248681 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.12255698 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.99140491 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.55371547 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.39865275 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.16053277 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.92447512 |
| 12 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.89565308 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.73862999 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.72634385 |
| 15 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.67197178 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47829016 |
| 17 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.44769906 |
| 18 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.44266019 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.43873302 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.34128441 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.33150841 |
| 22 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.32169021 |
| 23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.28928831 |
| 24 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27186522 |
| 25 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.27048600 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.24231797 |
| 27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.20420223 |
| 28 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.18706605 |
| 29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.17906022 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.15054594 |
| 31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.14160445 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.13393063 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.08218883 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.02637542 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.02545079 |
| 36 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.99941196 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.99602492 |
| 38 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.98297298 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.98025427 |
| 40 | Viral myocarditis_Homo sapiens_hsa05416 | 0.97163100 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.96432822 |
| 42 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.95406736 |
| 43 | Mismatch repair_Homo sapiens_hsa03430 | 0.94052389 |
| 44 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91696703 |
| 45 | Base excision repair_Homo sapiens_hsa03410 | 0.90559081 |
| 46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.88712922 |
| 47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.87291840 |
| 48 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.87240647 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85779297 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82546910 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.82514276 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.81782733 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.81495950 |
| 54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.80660670 |
| 55 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.80270033 |
| 56 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.79753641 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79426030 |
| 58 | DNA replication_Homo sapiens_hsa03030 | 0.78867452 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78606328 |
| 60 | Ribosome_Homo sapiens_hsa03010 | 0.78201779 |
| 61 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.78164685 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77869267 |
| 63 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.76576362 |
| 64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.76434476 |
| 65 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.75609024 |
| 66 | RNA transport_Homo sapiens_hsa03013 | 0.72914762 |
| 67 | Purine metabolism_Homo sapiens_hsa00230 | 0.71983245 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71939343 |
| 69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71371316 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68537672 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.66334037 |
| 72 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65597122 |
| 73 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65096365 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64776201 |
| 75 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.60915735 |
| 76 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.60536875 |
| 77 | Phototransduction_Homo sapiens_hsa04744 | 0.59411687 |
| 78 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.59153063 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57265231 |
| 80 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54576557 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.54263741 |
| 82 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.54163356 |
| 83 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.51664082 |
| 84 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.51113151 |
| 85 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.50774969 |
| 86 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50599535 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50116480 |
| 88 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.48691496 |
| 89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47044133 |
| 90 | Spliceosome_Homo sapiens_hsa03040 | 0.46851413 |
| 91 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.46846860 |
| 92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43656924 |
| 93 | ABC transporters_Homo sapiens_hsa02010 | 0.43123957 |
| 94 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.40186286 |
| 95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39056248 |
| 96 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.39001050 |
| 97 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.38082743 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36015219 |
| 99 | Histidine metabolism_Homo sapiens_hsa00340 | 0.35837283 |
| 100 | Leishmaniasis_Homo sapiens_hsa05140 | 0.35026157 |

