

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | growth hormone secretion (GO:0030252) | 9.64380109 |
| 2 | negative regulation of interleukin-1 beta production (GO:0032691) | 9.03562686 |
| 3 | adult feeding behavior (GO:0008343) | 9.00359546 |
| 4 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 7.63631145 |
| 5 | negative regulation of interleukin-1 production (GO:0032692) | 7.59012661 |
| 6 | regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) | 7.46091780 |
| 7 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 6.79374637 |
| 8 | regulation of response to food (GO:0032095) | 6.69770076 |
| 9 | response to food (GO:0032094) | 5.67770113 |
| 10 | one-carbon compound transport (GO:0019755) | 5.65131108 |
| 11 | regulation of appetite (GO:0032098) | 5.54246110 |
| 12 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 5.44612704 |
| 13 | hindbrain development (GO:0030902) | 5.26417460 |
| 14 | protein import into peroxisome matrix (GO:0016558) | 4.96223369 |
| 15 | negative regulation of peptidyl-serine phosphorylation (GO:0033137) | 4.92338637 |
| 16 | striated muscle atrophy (GO:0014891) | 4.82160294 |
| 17 | auditory receptor cell stereocilium organization (GO:0060088) | 4.68244113 |
| 18 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 4.62264477 |
| 19 | sperm capacitation (GO:0048240) | 4.39403482 |
| 20 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 4.38031079 |
| 21 | adaptation of signaling pathway (GO:0023058) | 4.33764470 |
| 22 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 4.24977802 |
| 23 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.21132535 |
| 24 | muscle atrophy (GO:0014889) | 4.16887892 |
| 25 | behavioral response to nicotine (GO:0035095) | 4.12009145 |
| 26 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 4.01863961 |
| 27 | skeletal muscle adaptation (GO:0043501) | 4.00383057 |
| 28 | positive regulation of gluconeogenesis (GO:0045722) | 3.95344276 |
| 29 | multicellular organism reproduction (GO:0032504) | 3.87808100 |
| 30 | positive thymic T cell selection (GO:0045059) | 3.87246184 |
| 31 | spinal cord development (GO:0021510) | 3.76956662 |
| 32 | positive regulation of sodium ion transport (GO:0010765) | 3.76622607 |
| 33 | protein kinase B signaling (GO:0043491) | 3.73475979 |
| 34 | inner ear receptor stereocilium organization (GO:0060122) | 3.63514133 |
| 35 | NAD biosynthetic process (GO:0009435) | 3.62034892 |
| 36 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.60082780 |
| 37 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.50539816 |
| 38 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.50539816 |
| 39 | cysteine metabolic process (GO:0006534) | 3.43308396 |
| 40 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 3.41036630 |
| 41 | decidualization (GO:0046697) | 3.37522981 |
| 42 | cornea development in camera-type eye (GO:0061303) | 3.37397094 |
| 43 | protein targeting to peroxisome (GO:0006625) | 3.35722251 |
| 44 | establishment of protein localization to peroxisome (GO:0072663) | 3.35722251 |
| 45 | protein localization to peroxisome (GO:0072662) | 3.35722251 |
| 46 | cellular response to pH (GO:0071467) | 3.27791724 |
| 47 | nephron tubule morphogenesis (GO:0072078) | 3.26307571 |
| 48 | nephron epithelium morphogenesis (GO:0072088) | 3.26307571 |
| 49 | regulation of mitochondrial membrane permeability (GO:0046902) | 3.23191186 |
| 50 | 2-oxoglutarate metabolic process (GO:0006103) | 3.22671980 |
| 51 | ovulation cycle (GO:0042698) | 3.21787185 |
| 52 | mannosylation (GO:0097502) | 3.21455365 |
| 53 | regulation of membrane permeability (GO:0090559) | 3.19981502 |
| 54 | male sex determination (GO:0030238) | 3.19025616 |
| 55 | positive regulation of fatty acid metabolic process (GO:0045923) | 3.18291774 |
| 56 | negative regulation of ERK1 and ERK2 cascade (GO:0070373) | 3.17890370 |
| 57 | urate metabolic process (GO:0046415) | 3.16959954 |
| 58 | ubiquinone biosynthetic process (GO:0006744) | 3.14923921 |
| 59 | protein refolding (GO:0042026) | 3.14727033 |
| 60 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.11019852 |
| 61 | intracellular protein transmembrane import (GO:0044743) | 3.10874071 |
| 62 | indolalkylamine metabolic process (GO:0006586) | 3.02953210 |
| 63 | positive T cell selection (GO:0043368) | 3.02287390 |
| 64 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.02086225 |
| 65 | regulation of male gonad development (GO:2000018) | 3.01439102 |
| 66 | neuronal action potential (GO:0019228) | 2.95388372 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.95175101 |
| 68 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.95175101 |
| 69 | peroxisomal transport (GO:0043574) | 2.94811022 |
| 70 | regulation of cilium movement (GO:0003352) | 2.94059271 |
| 71 | regulation of interleukin-1 beta production (GO:0032651) | 2.93758129 |
| 72 | telencephalon development (GO:0021537) | 2.93536353 |
| 73 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.92342069 |
| 74 | termination of RNA polymerase III transcription (GO:0006386) | 2.92342069 |
| 75 | sperm motility (GO:0030317) | 2.91506018 |
| 76 | C4-dicarboxylate transport (GO:0015740) | 2.89793508 |
| 77 | fusion of sperm to egg plasma membrane (GO:0007342) | 2.88046218 |
| 78 | regulation of digestive system process (GO:0044058) | 2.87572504 |
| 79 | organelle membrane fusion (GO:0090174) | 2.81684985 |
| 80 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.78599740 |
| 81 | negative regulation of interleukin-6 production (GO:0032715) | 2.78375219 |
| 82 | regulation of somitogenesis (GO:0014807) | 2.75428709 |
| 83 | ubiquinone metabolic process (GO:0006743) | 2.74550306 |
| 84 | endocrine pancreas development (GO:0031018) | 2.71440664 |
| 85 | regulation of histone phosphorylation (GO:0033127) | 2.70517918 |
| 86 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.70075208 |
| 87 | axonemal dynein complex assembly (GO:0070286) | 2.69275514 |
| 88 | negative regulation of inclusion body assembly (GO:0090084) | 2.67903537 |
| 89 | intracellular protein transmembrane transport (GO:0065002) | 2.64339789 |
| 90 | regulation of microtubule-based movement (GO:0060632) | 2.63619624 |
| 91 | pyridine nucleotide biosynthetic process (GO:0019363) | 2.61596642 |
| 92 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 2.61596642 |
| 93 | positive regulation of ion transmembrane transporter activity (GO:0032414) | 2.60741222 |
| 94 | somite development (GO:0061053) | 2.60109161 |
| 95 | regulation of dopamine secretion (GO:0014059) | 2.59451054 |
| 96 | artery development (GO:0060840) | 2.58302016 |
| 97 | renal tubule morphogenesis (GO:0061333) | 2.57796876 |
| 98 | positive regulation of response to nutrient levels (GO:0032109) | 2.55031787 |
| 99 | positive regulation of response to extracellular stimulus (GO:0032106) | 2.55031787 |
| 100 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 10.3472730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.95051762 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.28500191 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.52950692 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.26928634 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.96259864 |
| 6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.73250592 |
| 7 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.83274886 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.76982794 |
| 9 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.47977017 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.30150395 |
| 11 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.14615492 |
| 12 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.09005486 |
| 13 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.05944092 |
| 14 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.01370138 |
| 15 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.00286097 |
| 16 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.94977164 |
| 17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.82030005 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.79129176 |
| 19 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.71201123 |
| 20 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.68587213 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.67555074 |
| 22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67139615 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.62593660 |
| 24 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.55370212 |
| 25 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.54045029 |
| 26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.52785753 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.49541434 |
| 28 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.49539616 |
| 29 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.46466547 |
| 30 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.44193976 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.42333723 |
| 32 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40430732 |
| 33 | FUS_26573619_Chip-Seq_HEK293_Human | 1.34457555 |
| 34 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.33871794 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.31838352 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.31507065 |
| 37 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.31198503 |
| 38 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27872760 |
| 39 | GATA3_26560356_Chip-Seq_TH2_Human | 1.25538013 |
| 40 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.21322164 |
| 41 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.20271361 |
| 42 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.19367237 |
| 43 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.18440402 |
| 44 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.17656991 |
| 45 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.17353720 |
| 46 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.14634678 |
| 47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.13849416 |
| 48 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.13584679 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12898712 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12898712 |
| 51 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.10875110 |
| 52 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.09027816 |
| 53 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.08627452 |
| 54 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08511046 |
| 55 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.08088768 |
| 56 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.07705037 |
| 57 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06234800 |
| 58 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.04253734 |
| 59 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.03402516 |
| 60 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.02907839 |
| 61 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.02546221 |
| 62 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.02526657 |
| 63 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.01634958 |
| 64 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.01578756 |
| 65 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.01209749 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.01085156 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98683612 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98683612 |
| 69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97994861 |
| 70 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.97347385 |
| 71 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.96545474 |
| 72 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.95935630 |
| 73 | STAT3_23295773_ChIP-Seq_U87_Human | 0.95844583 |
| 74 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.95611593 |
| 75 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94862590 |
| 76 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.93478984 |
| 77 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.92988699 |
| 78 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.91807706 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 0.91528111 |
| 80 | AR_25329375_ChIP-Seq_VCAP_Human | 0.91387164 |
| 81 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.89701029 |
| 82 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.89585884 |
| 83 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.86700394 |
| 84 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.86363689 |
| 85 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.86028990 |
| 86 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.84100443 |
| 87 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.82835059 |
| 88 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.82625908 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.81736906 |
| 90 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.81670872 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.81376228 |
| 92 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.80940047 |
| 93 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.80786906 |
| 94 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.80384728 |
| 95 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.80167820 |
| 96 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.80144621 |
| 97 | P300_27268052_Chip-Seq_Bcells_Human | 0.79944756 |
| 98 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.79732247 |
| 99 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.79381223 |
| 100 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.79013958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.22589312 |
| 2 | MP0008872_abnormal_physiological_respon | 4.03182894 |
| 3 | MP0003868_abnormal_feces_composition | 3.76044867 |
| 4 | MP0005220_abnormal_exocrine_pancreas | 3.65163843 |
| 5 | MP0001984_abnormal_olfaction | 3.00064912 |
| 6 | MP0002653_abnormal_ependyma_morphology | 2.85458069 |
| 7 | MP0001986_abnormal_taste_sensitivity | 2.76420912 |
| 8 | MP0003303_peritoneal_inflammation | 2.76412131 |
| 9 | MP0009278_abnormal_bone_marrow | 2.47990396 |
| 10 | MP0003119_abnormal_digestive_system | 2.45382409 |
| 11 | MP0005499_abnormal_olfactory_system | 2.36373600 |
| 12 | MP0005394_taste/olfaction_phenotype | 2.36373600 |
| 13 | MP0004147_increased_porphyrin_level | 2.32880118 |
| 14 | MP0002736_abnormal_nociception_after | 2.27923725 |
| 15 | MP0001664_abnormal_digestion | 2.21926383 |
| 16 | MP0008877_abnormal_DNA_methylation | 2.13986349 |
| 17 | MP0000538_abnormal_urinary_bladder | 2.13171379 |
| 18 | MP0001663_abnormal_digestive_system | 1.96947166 |
| 19 | MP0004130_abnormal_muscle_cell | 1.93096362 |
| 20 | MP0003646_muscle_fatigue | 1.91014416 |
| 21 | MP0003880_abnormal_central_pattern | 1.86432377 |
| 22 | MP0001666_abnormal_nutrient_absorption | 1.86042721 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.82008138 |
| 24 | MP0010030_abnormal_orbit_morphology | 1.74868518 |
| 25 | MP0003638_abnormal_response/metabolism_ | 1.74133204 |
| 26 | MP0002876_abnormal_thyroid_physiology | 1.74070443 |
| 27 | MP0003959_abnormal_lean_body | 1.68356655 |
| 28 | MP0002102_abnormal_ear_morphology | 1.66991288 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.66192532 |
| 30 | MP0001919_abnormal_reproductive_system | 1.62157488 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.61305248 |
| 32 | MP0001501_abnormal_sleep_pattern | 1.61260030 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.61003507 |
| 34 | MP0003806_abnormal_nucleotide_metabolis | 1.59835535 |
| 35 | MP0006292_abnormal_olfactory_placode | 1.58490628 |
| 36 | MP0000427_abnormal_hair_cycle | 1.51239151 |
| 37 | MP0005448_abnormal_energy_balance | 1.51200868 |
| 38 | MP0004142_abnormal_muscle_tone | 1.48510856 |
| 39 | MP0003693_abnormal_embryo_hatching | 1.48478442 |
| 40 | MP0000383_abnormal_hair_follicle | 1.48118524 |
| 41 | MP0000470_abnormal_stomach_morphology | 1.47013799 |
| 42 | MP0005381_digestive/alimentary_phenotyp | 1.45993569 |
| 43 | MP0002928_abnormal_bile_duct | 1.43679375 |
| 44 | MP0003283_abnormal_digestive_organ | 1.43174383 |
| 45 | MP0006072_abnormal_retinal_apoptosis | 1.42531616 |
| 46 | MP0003195_calcinosis | 1.40760774 |
| 47 | MP0000015_abnormal_ear_pigmentation | 1.37658536 |
| 48 | MP0002234_abnormal_pharynx_morphology | 1.36952232 |
| 49 | MP0002160_abnormal_reproductive_system | 1.34433954 |
| 50 | MP0001486_abnormal_startle_reflex | 1.28584853 |
| 51 | MP0003172_abnormal_lysosome_physiology | 1.20835882 |
| 52 | MP0009046_muscle_twitch | 1.19358111 |
| 53 | MP0005423_abnormal_somatic_nervous | 1.18375988 |
| 54 | MP0000566_synostosis | 1.17237793 |
| 55 | MP0009384_cardiac_valve_regurgitation | 1.15662791 |
| 56 | MP0002095_abnormal_skin_pigmentation | 1.15217345 |
| 57 | MP0002272_abnormal_nervous_system | 1.11204278 |
| 58 | MP0002282_abnormal_trachea_morphology | 1.11052881 |
| 59 | MP0005076_abnormal_cell_differentiation | 1.10652815 |
| 60 | MP0003866_abnormal_defecation | 1.08672495 |
| 61 | MP0003011_delayed_dark_adaptation | 1.08493717 |
| 62 | MP0009745_abnormal_behavioral_response | 1.06870348 |
| 63 | MP0003183_abnormal_peptide_metabolism | 1.06089128 |
| 64 | MP0001502_abnormal_circadian_rhythm | 1.05089641 |
| 65 | MP0000569_abnormal_digit_pigmentation | 1.02799102 |
| 66 | MP0005397_hematopoietic_system_phenotyp | 1.01922732 |
| 67 | MP0001545_abnormal_hematopoietic_system | 1.01922732 |
| 68 | MP0005389_reproductive_system_phenotype | 1.00521137 |
| 69 | MP0000631_abnormal_neuroendocrine_gland | 0.99275548 |
| 70 | MP0005083_abnormal_biliary_tract | 0.97984603 |
| 71 | MP0009672_abnormal_birth_weight | 0.96725058 |
| 72 | MP0001529_abnormal_vocalization | 0.96290432 |
| 73 | MP0002063_abnormal_learning/memory/cond | 0.94655428 |
| 74 | MP0009053_abnormal_anal_canal | 0.94187007 |
| 75 | MP0005253_abnormal_eye_physiology | 0.94059908 |
| 76 | MP0002638_abnormal_pupillary_reflex | 0.93091348 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.92675776 |
| 78 | MP0004215_abnormal_myocardial_fiber | 0.92293312 |
| 79 | MP0010329_abnormal_lipoprotein_level | 0.91992015 |
| 80 | MP0002064_seizures | 0.88747197 |
| 81 | MP0001293_anophthalmia | 0.88182569 |
| 82 | MP0005386_behavior/neurological_phenoty | 0.85847202 |
| 83 | MP0004924_abnormal_behavior | 0.85847202 |
| 84 | MP0003787_abnormal_imprinting | 0.84838738 |
| 85 | MP0006036_abnormal_mitochondrial_physio | 0.84022596 |
| 86 | MP0005452_abnormal_adipose_tissue | 0.83578832 |
| 87 | MP0001177_atelectasis | 0.82968155 |
| 88 | MP0001440_abnormal_grooming_behavior | 0.82662472 |
| 89 | MP0002572_abnormal_emotion/affect_behav | 0.82490427 |
| 90 | MP0002067_abnormal_sensory_capabilities | 0.81415948 |
| 91 | MP0001905_abnormal_dopamine_level | 0.78874552 |
| 92 | MP0000026_abnormal_inner_ear | 0.77812150 |
| 93 | MP0005646_abnormal_pituitary_gland | 0.76378750 |
| 94 | MP0000579_abnormal_nail_morphology | 0.73853279 |
| 95 | MP0004133_heterotaxia | 0.72371264 |
| 96 | MP0002557_abnormal_social/conspecific_i | 0.70065494 |
| 97 | MP0001944_abnormal_pancreas_morphology | 0.69665014 |
| 98 | MP0006276_abnormal_autonomic_nervous | 0.68885860 |
| 99 | MP0002734_abnormal_mechanical_nocicepti | 0.67925666 |
| 100 | MP0005647_abnormal_sex_gland | 0.67301793 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type II lissencephaly (HP:0007260) | 5.85837485 |
| 2 | Birth length less than 3rd percentile (HP:0003561) | 5.61568481 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 5.56881441 |
| 4 | Abnormality of alanine metabolism (HP:0010916) | 5.56881441 |
| 5 | Hyperalaninemia (HP:0003348) | 5.56881441 |
| 6 | Global brain atrophy (HP:0002283) | 5.13347363 |
| 7 | Retinal dysplasia (HP:0007973) | 4.34941702 |
| 8 | Pendular nystagmus (HP:0012043) | 3.87839104 |
| 9 | Cerebellar dysplasia (HP:0007033) | 3.74212315 |
| 10 | Neoplasm of head and neck (HP:0012288) | 3.65013426 |
| 11 | Esophageal neoplasm (HP:0100751) | 3.65013426 |
| 12 | Breast hypoplasia (HP:0003187) | 3.56204372 |
| 13 | Pancreatic fibrosis (HP:0100732) | 3.49201563 |
| 14 | Gastrointestinal infarctions (HP:0005244) | 3.48098137 |
| 15 | Nasal polyposis (HP:0100582) | 3.47781253 |
| 16 | Rectal prolapse (HP:0002035) | 3.44748947 |
| 17 | Chorioretinal atrophy (HP:0000533) | 3.33806527 |
| 18 | Spastic tetraparesis (HP:0001285) | 3.28216231 |
| 19 | Prominent supraorbital ridges (HP:0000336) | 3.13704384 |
| 20 | Pancreatic cysts (HP:0001737) | 3.12327381 |
| 21 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.02078955 |
| 22 | Absent/shortened dynein arms (HP:0200106) | 3.02078955 |
| 23 | Abnormality of the nasal mucosa (HP:0000433) | 2.97497073 |
| 24 | Attenuation of retinal blood vessels (HP:0007843) | 2.94174676 |
| 25 | Progressive inability to walk (HP:0002505) | 2.89836705 |
| 26 | Mesangial abnormality (HP:0001966) | 2.89189027 |
| 27 | Nephronophthisis (HP:0000090) | 2.88119147 |
| 28 | Gonadal dysgenesis (HP:0000133) | 2.87855761 |
| 29 | Inability to walk (HP:0002540) | 2.85525310 |
| 30 | Disproportionate short-trunk short stature (HP:0003521) | 2.82548518 |
| 31 | Brushfield spots (HP:0001088) | 2.76949293 |
| 32 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.75575995 |
| 33 | Tubular atrophy (HP:0000092) | 2.74294677 |
| 34 | Hypoplastic labia majora (HP:0000059) | 2.70999361 |
| 35 | Hyperventilation (HP:0002883) | 2.70516700 |
| 36 | Abnormality of nail color (HP:0100643) | 2.65063700 |
| 37 | Long nose (HP:0003189) | 2.61910509 |
| 38 | Congenital stationary night blindness (HP:0007642) | 2.61101145 |
| 39 | Patellar aplasia (HP:0006443) | 2.59654161 |
| 40 | Lissencephaly (HP:0001339) | 2.57399034 |
| 41 | True hermaphroditism (HP:0010459) | 2.55837212 |
| 42 | Abnormality of midbrain morphology (HP:0002418) | 2.51864632 |
| 43 | Molar tooth sign on MRI (HP:0002419) | 2.51864632 |
| 44 | Atonic seizures (HP:0010819) | 2.51825285 |
| 45 | Progressive microcephaly (HP:0000253) | 2.49186729 |
| 46 | Anterior segment dysgenesis (HP:0007700) | 2.46484946 |
| 47 | Abolished electroretinogram (ERG) (HP:0000550) | 2.45466203 |
| 48 | Rib fusion (HP:0000902) | 2.44817168 |
| 49 | Abnormality of the labia majora (HP:0012881) | 2.43466380 |
| 50 | Abnormal ciliary motility (HP:0012262) | 2.41970452 |
| 51 | Abnormality of the vertebral endplates (HP:0005106) | 2.39534254 |
| 52 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.39303266 |
| 53 | Ulnar claw (HP:0001178) | 2.38389761 |
| 54 | Abnormality of the renal cortex (HP:0011035) | 2.37967044 |
| 55 | Partial agenesis of the corpus callosum (HP:0001338) | 2.37008444 |
| 56 | Fair hair (HP:0002286) | 2.34777281 |
| 57 | Abnormality of the renal medulla (HP:0100957) | 2.29359995 |
| 58 | Metaphyseal dysplasia (HP:0100255) | 2.26947724 |
| 59 | Optic disc pallor (HP:0000543) | 2.25613238 |
| 60 | Increased corneal curvature (HP:0100692) | 2.24327198 |
| 61 | Keratoconus (HP:0000563) | 2.24327198 |
| 62 | Renal cortical cysts (HP:0000803) | 2.23100683 |
| 63 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.22532173 |
| 64 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.22532173 |
| 65 | Pachygyria (HP:0001302) | 2.22491283 |
| 66 | Neonatal onset (HP:0003623) | 2.19993459 |
| 67 | Biliary tract neoplasm (HP:0100574) | 2.19161708 |
| 68 | Abnormal biliary tract physiology (HP:0012439) | 2.16061011 |
| 69 | Bile duct proliferation (HP:0001408) | 2.16061011 |
| 70 | Generalized aminoaciduria (HP:0002909) | 2.16041870 |
| 71 | High pitched voice (HP:0001620) | 2.15096373 |
| 72 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.15011609 |
| 73 | Hypochromic anemia (HP:0001931) | 2.14401205 |
| 74 | Brittle hair (HP:0002299) | 2.13858564 |
| 75 | Abnormality of the fingertips (HP:0001211) | 2.13163374 |
| 76 | Abnormality of the wing of the ilium (HP:0011867) | 2.05947696 |
| 77 | Delayed CNS myelination (HP:0002188) | 2.05833271 |
| 78 | Bronchomalacia (HP:0002780) | 2.04847393 |
| 79 | Alkalosis (HP:0001948) | 2.04503135 |
| 80 | Rhinitis (HP:0012384) | 2.03556761 |
| 81 | Hypomagnesemia (HP:0002917) | 2.02549298 |
| 82 | Clumsiness (HP:0002312) | 2.02272630 |
| 83 | Abnormality of serum amino acid levels (HP:0003112) | 2.02151142 |
| 84 | Abnormality of macular pigmentation (HP:0008002) | 2.02025407 |
| 85 | Neoplasm of the rectum (HP:0100743) | 1.99295702 |
| 86 | Acute encephalopathy (HP:0006846) | 1.97051051 |
| 87 | Ulnar deviation of the wrist (HP:0003049) | 1.96092242 |
| 88 | Abnormality of the vitreous humor (HP:0004327) | 1.94912044 |
| 89 | Abnormal number of erythroid precursors (HP:0012131) | 1.94576181 |
| 90 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.93604344 |
| 91 | Intellectual disability, progressive (HP:0006887) | 1.91627564 |
| 92 | Labial hypoplasia (HP:0000066) | 1.90520818 |
| 93 | Female pseudohermaphroditism (HP:0010458) | 1.89413859 |
| 94 | Cervical subluxation (HP:0003308) | 1.87331407 |
| 95 | Hepatic necrosis (HP:0002605) | 1.86955974 |
| 96 | Medial flaring of the eyebrow (HP:0010747) | 1.84269268 |
| 97 | CNS demyelination (HP:0007305) | 1.84003108 |
| 98 | Acute necrotizing encephalopathy (HP:0006965) | 1.80138468 |
| 99 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.79194155 |
| 100 | Hypoplastic female external genitalia (HP:0012815) | 1.76915896 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PIK3CA | 2.78542813 |
| 2 | FRK | 2.64806039 |
| 3 | ERBB4 | 2.40701014 |
| 4 | WNK4 | 2.17496745 |
| 5 | BMPR1B | 2.08127688 |
| 6 | CDK8 | 2.03737534 |
| 7 | STK39 | 2.00747324 |
| 8 | INSRR | 11.7336712 |
| 9 | MAPKAPK5 | 1.99947115 |
| 10 | MAP3K11 | 1.79613150 |
| 11 | RPS6KA5 | 1.65864352 |
| 12 | BCKDK | 1.36242057 |
| 13 | CAMKK2 | 1.34536486 |
| 14 | PKN1 | 1.29867553 |
| 15 | LIMK1 | 1.27801018 |
| 16 | RPS6KA2 | 1.27507109 |
| 17 | RPS6KA6 | 1.26633131 |
| 18 | STK11 | 1.23118252 |
| 19 | ADRBK2 | 1.16221542 |
| 20 | TSSK6 | 1.15984990 |
| 21 | OXSR1 | 1.15625010 |
| 22 | GRK1 | 1.14413674 |
| 23 | ABL2 | 1.13214656 |
| 24 | VRK2 | 1.04505557 |
| 25 | RPS6KB1 | 1.04131284 |
| 26 | AKT2 | 0.98013073 |
| 27 | TAOK3 | 0.96530532 |
| 28 | PAK3 | 0.91690267 |
| 29 | TGFBR1 | 0.90916130 |
| 30 | PRKCZ | 0.88782810 |
| 31 | NME1 | 0.85933984 |
| 32 | RPS6KL1 | 0.85642736 |
| 33 | RPS6KC1 | 0.85642736 |
| 34 | IKBKB | 0.80692128 |
| 35 | ADRBK1 | 0.79717596 |
| 36 | PIK3CG | 0.79040027 |
| 37 | CAMKK1 | 0.71143027 |
| 38 | KIT | 0.71023087 |
| 39 | PNCK | 0.70723644 |
| 40 | TLK1 | 0.70536326 |
| 41 | JAK3 | 0.70383316 |
| 42 | TIE1 | 0.69243618 |
| 43 | PHKG1 | 0.68984905 |
| 44 | PHKG2 | 0.68984905 |
| 45 | PASK | 0.68638654 |
| 46 | GRK7 | 0.68140619 |
| 47 | PDK2 | 0.64412318 |
| 48 | MARK1 | 0.61768120 |
| 49 | MAPK11 | 0.61266414 |
| 50 | MAP2K6 | 0.59658796 |
| 51 | ZAK | 0.59042462 |
| 52 | NTRK3 | 0.57223563 |
| 53 | CDK3 | 0.56397756 |
| 54 | VRK1 | 0.56149205 |
| 55 | DYRK1B | 0.54450564 |
| 56 | SRPK1 | 0.54395145 |
| 57 | PINK1 | 0.54148030 |
| 58 | PLK2 | 0.52464996 |
| 59 | BUB1 | 0.51289685 |
| 60 | CAMK1D | 0.49240080 |
| 61 | TNK2 | 0.49174320 |
| 62 | PRKCG | 0.49065114 |
| 63 | TEC | 0.48188585 |
| 64 | TTK | 0.48065063 |
| 65 | DAPK2 | 0.46823229 |
| 66 | CAMK2A | 0.46765706 |
| 67 | PRKCA | 0.46749208 |
| 68 | CHUK | 0.46409024 |
| 69 | CAMK2G | 0.46096709 |
| 70 | TYRO3 | 0.42912648 |
| 71 | PDGFRB | 0.41394923 |
| 72 | ITK | 0.40805849 |
| 73 | AKT3 | 0.40793165 |
| 74 | ATR | 0.40727981 |
| 75 | PRKCE | 0.40382643 |
| 76 | CAMK1G | 0.39873470 |
| 77 | CSNK2A1 | 0.39405153 |
| 78 | CDK9 | 0.39396020 |
| 79 | WNK3 | 0.38792487 |
| 80 | MKNK1 | 0.37620985 |
| 81 | MAPK12 | 0.37016375 |
| 82 | PRKG1 | 0.35225386 |
| 83 | MUSK | 0.35099421 |
| 84 | CAMK1 | 0.34957276 |
| 85 | OBSCN | 0.33670342 |
| 86 | MKNK2 | 0.33348565 |
| 87 | MAP4K1 | 0.33233744 |
| 88 | ERBB2 | 0.32866256 |
| 89 | TRIM28 | 0.32672419 |
| 90 | PRKACA | 0.32177647 |
| 91 | TYK2 | 0.31806830 |
| 92 | ATM | 0.31385968 |
| 93 | PRKCQ | 0.30666788 |
| 94 | ABL1 | 0.28864558 |
| 95 | LCK | 0.28655859 |
| 96 | PTK2B | 0.28021327 |
| 97 | PRKDC | 0.27635544 |
| 98 | JAK2 | 0.26089367 |
| 99 | PTK6 | 0.25794050 |
| 100 | PRKACB | 0.24938867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 4.97651071 |
| 2 | Butanoate metabolism_Homo sapiens_hsa00650 | 4.16208377 |
| 3 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 4.07099648 |
| 4 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.96407426 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 3.06047543 |
| 6 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.80238696 |
| 7 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.46556168 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.44381264 |
| 9 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.39465363 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.30579761 |
| 11 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.28418041 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.28051361 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.22551072 |
| 14 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.21997189 |
| 15 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.97318360 |
| 16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.95587862 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.88507188 |
| 18 | Sulfur relay system_Homo sapiens_hsa04122 | 1.74869477 |
| 19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.74659409 |
| 20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.70503859 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.62291278 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.62050354 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.56195741 |
| 24 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.48606963 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.43882543 |
| 26 | Parkinsons disease_Homo sapiens_hsa05012 | 1.40763717 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.39818606 |
| 28 | Proteasome_Homo sapiens_hsa03050 | 1.34892077 |
| 29 | Nicotine addiction_Homo sapiens_hsa05033 | 1.25092723 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.23367536 |
| 31 | Peroxisome_Homo sapiens_hsa04146 | 1.16581731 |
| 32 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.09565924 |
| 33 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.03376429 |
| 34 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.99785163 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.96733797 |
| 36 | Histidine metabolism_Homo sapiens_hsa00340 | 0.95776108 |
| 37 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.92418244 |
| 38 | ABC transporters_Homo sapiens_hsa02010 | 0.92210565 |
| 39 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.88611407 |
| 40 | Ribosome_Homo sapiens_hsa03010 | 0.83249238 |
| 41 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.80655909 |
| 42 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.78032332 |
| 43 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.77714816 |
| 44 | Olfactory transduction_Homo sapiens_hsa04740 | 0.76303125 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 0.72621118 |
| 46 | Taste transduction_Homo sapiens_hsa04742 | 0.72594774 |
| 47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.72267462 |
| 48 | Insulin secretion_Homo sapiens_hsa04911 | 0.71948325 |
| 49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.69271927 |
| 50 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.68900935 |
| 51 | Alzheimers disease_Homo sapiens_hsa05010 | 0.68673023 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.68601204 |
| 53 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67309509 |
| 54 | Retinol metabolism_Homo sapiens_hsa00830 | 0.67067903 |
| 55 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.65948882 |
| 56 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.63492403 |
| 57 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63404066 |
| 58 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.63067957 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62559517 |
| 60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.61321460 |
| 61 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.60207045 |
| 62 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.56850114 |
| 63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.55132519 |
| 64 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.54573875 |
| 65 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.53029411 |
| 66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.50533730 |
| 67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.48528108 |
| 68 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.48396433 |
| 69 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.45816120 |
| 70 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44775776 |
| 71 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.44283250 |
| 72 | Cocaine addiction_Homo sapiens_hsa05030 | 0.43404630 |
| 73 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.42238037 |
| 74 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.40905494 |
| 75 | Asthma_Homo sapiens_hsa05310 | 0.38415634 |
| 76 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.38030369 |
| 77 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37787552 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.36933102 |
| 79 | Spliceosome_Homo sapiens_hsa03040 | 0.34962565 |
| 80 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34320213 |
| 81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.32125544 |
| 82 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.31458171 |
| 83 | Mineral absorption_Homo sapiens_hsa04978 | 0.30412419 |
| 84 | RNA degradation_Homo sapiens_hsa03018 | 0.29218331 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.27702356 |
| 86 | Lysosome_Homo sapiens_hsa04142 | 0.26113466 |
| 87 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.25790236 |
| 88 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.24077637 |
| 89 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.22848592 |
| 90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22239467 |
| 91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.21954637 |
| 92 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.21244487 |
| 93 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.20060590 |
| 94 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.19627003 |
| 95 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.18945945 |
| 96 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.17915487 |
| 97 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.17571713 |
| 98 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.16134329 |
| 99 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.16038964 |
| 100 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.16029293 |

