EIF4A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.20753419
2nuclear pore organization (GO:0006999)4.90116981
3DNA replication-dependent nucleosome organization (GO:0034723)4.85803088
4DNA replication-dependent nucleosome assembly (GO:0006335)4.85803088
5folic acid-containing compound biosynthetic process (GO:0009396)4.70892205
6nuclear pore complex assembly (GO:0051292)4.67921224
7protein localization to kinetochore (GO:0034501)4.58189896
8mitotic nuclear envelope disassembly (GO:0007077)4.38225208
9establishment of integrated proviral latency (GO:0075713)4.31017353
10IMP biosynthetic process (GO:0006188)4.29841819
11DNA replication initiation (GO:0006270)4.19678381
12nucleobase biosynthetic process (GO:0046112)4.15654184
13nuclear envelope disassembly (GO:0051081)4.13280899
14membrane disassembly (GO:0030397)4.13280899
15DNA strand elongation involved in DNA replication (GO:0006271)4.11645222
16ribosome assembly (GO:0042255)4.09894585
17formation of translation preinitiation complex (GO:0001731)4.01161502
18protein complex localization (GO:0031503)3.99292546
19cellular protein complex localization (GO:0034629)3.90234340
20DNA strand elongation (GO:0022616)3.88341346
21regulation of gene silencing by RNA (GO:0060966)3.87971961
22regulation of posttranscriptional gene silencing (GO:0060147)3.87971961
23regulation of gene silencing by miRNA (GO:0060964)3.87971961
24COPI coating of Golgi vesicle (GO:0048205)3.86691959
25Golgi transport vesicle coating (GO:0048200)3.86691959
26maturation of SSU-rRNA (GO:0030490)3.85317113
27viral mRNA export from host cell nucleus (GO:0046784)3.83571170
28IMP metabolic process (GO:0046040)3.81070979
29protein localization to chromosome, centromeric region (GO:0071459)3.80393929
30mitotic metaphase plate congression (GO:0007080)3.76202425
31purine nucleobase biosynthetic process (GO:0009113)3.75732376
32DNA duplex unwinding (GO:0032508)3.70800859
33DNA geometric change (GO:0032392)3.69845253
34regulation of translational termination (GO:0006449)3.66095439
35ribosomal small subunit biogenesis (GO:0042274)3.63316854
36mitotic chromosome condensation (GO:0007076)3.56085563
37regulation of translational fidelity (GO:0006450)3.55468619
38pore complex assembly (GO:0046931)3.54760783
39regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.54492402
40telomere maintenance via semi-conservative replication (GO:0032201)3.52689724
41regulation of histone H3-K9 methylation (GO:0051570)3.50768485
42establishment of viral latency (GO:0019043)3.49397416
43ribosomal small subunit assembly (GO:0000028)3.48917097
44regulation of spindle organization (GO:0090224)3.47277277
45heterochromatin organization (GO:0070828)3.45285996
46sister chromatid segregation (GO:0000819)3.40129870
47translational termination (GO:0006415)3.39803798
48viral transcription (GO:0019083)3.39733783
49mitotic sister chromatid segregation (GO:0000070)3.35242992
50pre-miRNA processing (GO:0031054)3.33817825
51nuclear envelope reassembly (GO:0031468)3.33574166
52mitotic nuclear envelope reassembly (GO:0007084)3.33574166
53ribosomal large subunit biogenesis (GO:0042273)3.30412007
54DNA replication checkpoint (GO:0000076)3.30340035
55ribosome biogenesis (GO:0042254)3.29439226
56regulation of mammary gland epithelial cell proliferation (GO:0033599)3.28556026
57negative regulation of histone methylation (GO:0031061)3.28073650
58metaphase plate congression (GO:0051310)3.28050543
59chromatin assembly (GO:0031497)3.27916630
60nuclear envelope organization (GO:0006998)3.25832438
61dosage compensation (GO:0007549)3.25443086
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.25337879
63* translational initiation (GO:0006413)3.23136933
64mitotic recombination (GO:0006312)3.21863940
65chromatin assembly or disassembly (GO:0006333)3.20227515
66chromatin remodeling at centromere (GO:0031055)3.19969333
67regulation of helicase activity (GO:0051095)3.19171116
68positive regulation of chromosome segregation (GO:0051984)3.19056630
69translational elongation (GO:0006414)3.18086944
70telomere maintenance via recombination (GO:0000722)3.15819602
71peptidyl-arginine N-methylation (GO:0035246)3.15128027
72peptidyl-arginine methylation (GO:0018216)3.15128027
73peptidyl-arginine omega-N-methylation (GO:0035247)3.14698294
74DNA replication-independent nucleosome assembly (GO:0006336)3.13616749
75DNA replication-independent nucleosome organization (GO:0034724)3.13616749
76nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.13098271
77nucleobase-containing small molecule interconversion (GO:0015949)3.11981033
78ribonucleoprotein complex biogenesis (GO:0022613)3.11834257
79CENP-A containing nucleosome assembly (GO:0034080)3.09916723
80regulation of mitotic spindle organization (GO:0060236)3.07158962
81regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.06751822
82regulation of sister chromatid cohesion (GO:0007063)3.06747199
83negative regulation of RNA splicing (GO:0033119)3.05659680
84regulation of centrosome cycle (GO:0046605)3.00605828
85somatic diversification of immune receptors via somatic mutation (GO:0002566)3.00088218
86somatic hypermutation of immunoglobulin genes (GO:0016446)3.00088218
87regulation of chromosome segregation (GO:0051983)2.97546870
88translesion synthesis (GO:0019985)2.95249313
89telomere maintenance via telomere lengthening (GO:0010833)2.93886525
90spliceosomal tri-snRNP complex assembly (GO:0000244)2.93245381
91DNA conformation change (GO:0071103)2.91871664
92establishment of chromosome localization (GO:0051303)2.91418303
93regulation of DNA damage checkpoint (GO:2000001)2.90945953
94positive regulation of SMAD protein import into nucleus (GO:0060391)2.89895308
95negative regulation of chromosome segregation (GO:0051985)2.89761056
96paraxial mesoderm development (GO:0048339)2.89571551
97mitotic sister chromatid cohesion (GO:0007064)2.89418880
98spindle checkpoint (GO:0031577)2.87324308
99rRNA transcription (GO:0009303)2.87267368
100folic acid metabolic process (GO:0046655)2.85986829
101histone H2A monoubiquitination (GO:0035518)2.85676248
102keratinization (GO:0031424)2.85669126
103spindle assembly checkpoint (GO:0071173)2.84984569
104proline biosynthetic process (GO:0006561)2.84607547
105mitotic spindle assembly checkpoint (GO:0007094)2.83946798
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.83915628
107negative regulation of sister chromatid segregation (GO:0033046)2.83915628
108negative regulation of mitotic sister chromatid separation (GO:2000816)2.83915628
109negative regulation of mitotic sister chromatid segregation (GO:0033048)2.83915628
110regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.83257161
111mitotic spindle checkpoint (GO:0071174)2.83241298
112negative regulation of DNA repair (GO:0045738)2.82768506
113protein localization to chromosome (GO:0034502)2.82240140
114chaperone-mediated protein complex assembly (GO:0051131)2.82125440
115postreplication repair (GO:0006301)2.82099614
116histone arginine methylation (GO:0034969)2.80956702
117negative regulation of mRNA processing (GO:0050686)2.80790301
118spliceosomal snRNP assembly (GO:0000387)2.80748043
119nucleotide-excision repair, DNA gap filling (GO:0006297)2.80731352
120negative regulation of mRNA metabolic process (GO:1903312)2.71779977
121DNA topological change (GO:0006265)2.66054911
122chromosome condensation (GO:0030261)2.65374981
123protein export from nucleus (GO:0006611)2.63899920
124rRNA processing (GO:0006364)2.60531193
125regulation of RNA export from nucleus (GO:0046831)2.58811603
126regulation of translational elongation (GO:0006448)2.57622447
127viral life cycle (GO:0019058)2.55090848
128mitochondrial fusion (GO:0008053)2.54711375
129L-serine metabolic process (GO:0006563)2.54421614
130tRNA aminoacylation for protein translation (GO:0006418)2.53457386
131positive regulation of DNA-templated transcription, elongation (GO:0032786)2.53083054
132mitochondrial DNA metabolic process (GO:0032042)2.51517124
133RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.51451643
134mRNA splicing, via spliceosome (GO:0000398)2.51451643
135maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.47023549
136SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.46769792
137tRNA aminoacylation (GO:0043039)2.46706340
138amino acid activation (GO:0043038)2.46706340
139rRNA metabolic process (GO:0016072)2.43998813
140non-recombinational repair (GO:0000726)2.43912499
141double-strand break repair via nonhomologous end joining (GO:0006303)2.43912499
142retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.43689213

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.67014612
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.41759411
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.10116806
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.57490931
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.41764573
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.05587595
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.94912875
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.91847687
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.84865263
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.66981251
11* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41681611
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.38214375
13* XRN2_22483619_ChIP-Seq_HELA_Human2.16475249
14AR_21909140_ChIP-Seq_LNCAP_Human2.16456556
15KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.09680828
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.05466619
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.03211623
18E2F1_21310950_ChIP-Seq_MCF-7_Human2.01828571
19* MYC_22102868_ChIP-Seq_BL_Human1.99536784
20CREB1_15753290_ChIP-ChIP_HEK293T_Human1.96444910
21* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94761271
22POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.92208391
23* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.91281125
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.82970635
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82927464
26* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80845703
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80581133
28POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78712383
29KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.78445400
30GABP_17652178_ChIP-ChIP_JURKAT_Human1.76948168
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.74594786
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74576036
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70486742
34* VDR_23849224_ChIP-Seq_CD4+_Human1.67734691
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.62361291
36ZFX_18555785_ChIP-Seq_MESCs_Mouse1.60588428
37* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.57681876
38DCP1A_22483619_ChIP-Seq_HELA_Human1.54635608
39* TTF2_22483619_ChIP-Seq_HELA_Human1.54391805
40CIITA_25753668_ChIP-Seq_RAJI_Human1.51105933
41FOXP3_21729870_ChIP-Seq_TREG_Human1.47226721
42GABP_19822575_ChIP-Seq_HepG2_Human1.45976264
43TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.43528345
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43142365
45KDM5A_27292631_Chip-Seq_BREAST_Human1.42020538
46* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.40775139
47SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39941652
48SALL1_21062744_ChIP-ChIP_HESCs_Human1.38162212
49* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37541148
50ELK3_25401928_ChIP-Seq_HUVEC_Human1.36844679
51* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.35996463
52CLOCK_20551151_ChIP-Seq_293T_Human1.35118802
53* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.34366542
54ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33225090
55TCF3_18692474_ChIP-Seq_MEFs_Mouse1.32809223
56ELK1_19687146_ChIP-ChIP_HELA_Human1.32737144
57THAP11_20581084_ChIP-Seq_MESCs_Mouse1.31911714
58* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30517607
59KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.30310261
60KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.29263740
61KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.29263740
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.29263740
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.28753327
64TFEB_21752829_ChIP-Seq_HELA_Human1.27727945
65* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.27001739
66ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.26699694
67ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.25923114
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.25750623
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24979900
70TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24924183
71SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22572206
72NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22368062
73PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.19248015
74* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.18384115
75* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.18153551
76CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.17619414
77ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.16040821
78ELF1_17652178_ChIP-ChIP_JURKAT_Human1.15846432
79TP63_17297297_ChIP-ChIP_HaCaT_Human1.15838972
80VDR_21846776_ChIP-Seq_THP-1_Human1.13041089
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.12665692
82HOXB4_20404135_ChIP-ChIP_EML_Mouse1.12327498
83NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.11703653
84* RACK7_27058665_Chip-Seq_MCF-7_Human1.10978404
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.10012248
86TP63_19390658_ChIP-ChIP_HaCaT_Human1.09317111
87RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08862623
88RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08732723
89SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.07968129
90ZNF263_19887448_ChIP-Seq_K562_Human1.07733139
91NANOG_21062744_ChIP-ChIP_HESCs_Human1.07247135
92* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06627702
93NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06412751
94TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.03891813
95CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.03615743
96SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03591691
97TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03207844
98TCF3_18692474_ChIP-Seq_MESCs_Mouse1.02968649
99FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02543772
100E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02124053
101PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99328214
102* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98848573
103SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.98734242
104SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98648005
105KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98020889
106YY1_21170310_ChIP-Seq_MESCs_Mouse0.97441510
107SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96948561
108PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95817218
109* UBF1/2_26484160_Chip-Seq_HMECs_Human0.94929388
110ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94923944
111STAT6_21828071_ChIP-Seq_BEAS2B_Human0.94803504
112* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.94265103
113* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93974751
114* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.93785143
115HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.92981580
116* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.92843439
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90615643
118SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.89683350
119CHD1_26751641_Chip-Seq_LNCaP_Human0.89557716
120* SOX17_20123909_ChIP-Seq_XEN_Mouse0.89407290
121ATF3_27146783_Chip-Seq_COLON_Human0.89026185

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.39904388
2MP0003111_abnormal_nucleus_morphology3.91057767
3MP0004957_abnormal_blastocyst_morpholog3.90423403
4MP0010094_abnormal_chromosome_stability3.81100027
5MP0003077_abnormal_cell_cycle3.47460931
6MP0010352_gastrointestinal_tract_polyps3.27477251
7MP0008057_abnormal_DNA_replication2.78499745
8MP0001730_embryonic_growth_arrest2.56937704
9MP0002796_impaired_skin_barrier2.54458924
10MP0003123_paternal_imprinting2.54094147
11MP0003705_abnormal_hypodermis_morpholog2.53090965
12MP0010307_abnormal_tumor_latency2.52327290
13MP0008007_abnormal_cellular_replicative2.48658268
14MP0000350_abnormal_cell_proliferation2.34403426
15MP0008058_abnormal_DNA_repair2.28676733
16MP0008932_abnormal_embryonic_tissue2.27558427
17MP0005076_abnormal_cell_differentiation2.17084332
18MP0000537_abnormal_urethra_morphology2.05859202
19MP0001672_abnormal_embryogenesis/_devel1.95812034
20MP0005380_embryogenesis_phenotype1.95812034
21MP0004197_abnormal_fetal_growth/weight/1.92001898
22MP0001697_abnormal_embryo_size1.88540009
23MP0002084_abnormal_developmental_patter1.86889113
24MP0002085_abnormal_embryonic_tissue1.81096103
25MP0004272_abnormal_basement_membrane1.80853744
26MP0003984_embryonic_growth_retardation1.77716687
27MP0002088_abnormal_embryonic_growth/wei1.76012025
28MP0010234_abnormal_vibrissa_follicle1.75001138
29MP0002086_abnormal_extraembryonic_tissu1.74517865
30MP0005451_abnormal_body_composition1.73485583
31MP0002080_prenatal_lethality1.73348133
32MP0010030_abnormal_orbit_morphology1.63853304
33MP0009053_abnormal_anal_canal1.62922634
34MP0003567_abnormal_fetal_cardiomyocyte1.62596927
35MP0002396_abnormal_hematopoietic_system1.54385134
36MP0003566_abnormal_cell_adhesion1.52050565
37MP0000579_abnormal_nail_morphology1.50510152
38MP0000490_abnormal_crypts_of1.46433723
39MP0001216_abnormal_epidermal_layer1.45047120
40MP0002060_abnormal_skin_morphology1.44122402
41MP0003806_abnormal_nucleotide_metabolis1.38200933
42MP0003786_premature_aging1.38126285
43MP0004808_abnormal_hematopoietic_stem1.37738829
44MP0005058_abnormal_lysosome_morphology1.35573534
45MP0001293_anophthalmia1.34013302
46MP0003890_abnormal_embryonic-extraembry1.33174080
47MP0003121_genomic_imprinting1.32408701
48MP0001849_ear_inflammation1.31754891
49MP0008260_abnormal_autophagy1.31381154
50MP0003119_abnormal_digestive_system1.29798694
51MP0000313_abnormal_cell_death1.26654821
52MP0002009_preneoplasia1.24587339
53MP0002019_abnormal_tumor_incidence1.24222231
54MP0005023_abnormal_wound_healing1.22261726
55MP0006054_spinal_hemorrhage1.19954702
56MP0005257_abnormal_intraocular_pressure1.18052305
57MP0000733_abnormal_muscle_development1.18051240
58MP0003191_abnormal_cellular_cholesterol1.16212987
59MP0008877_abnormal_DNA_methylation1.12786586
60MP0009278_abnormal_bone_marrow1.08656196
61MP0004947_skin_inflammation1.08243116
62MP0002111_abnormal_tail_morphology1.08161453
63MP0001915_intracranial_hemorrhage1.08043758
64MP0000428_abnormal_craniofacial_morphol1.06035856
65MP0002098_abnormal_vibrissa_morphology1.05728557
66MP0009672_abnormal_birth_weight1.05105626
67MP0002653_abnormal_ependyma_morphology1.03472138
68MP0000762_abnormal_tongue_morphology1.02687408
69MP0005623_abnormal_meninges_morphology1.01656169
70MP0000003_abnormal_adipose_tissue1.00972941
71MP0003937_abnormal_limbs/digits/tail_de1.00549882
72MP0003941_abnormal_skin_development0.99414865
73MP0002092_abnormal_eye_morphology0.99295028
74MP0003315_abnormal_perineum_morphology0.98333130
75MP0003091_abnormal_cell_migration0.97136586
76MP0003718_maternal_effect0.96478101
77MP0009840_abnormal_foam_cell0.94906773
78MP0002877_abnormal_melanocyte_morpholog0.93969488
79MP0002697_abnormal_eye_size0.93737324
80MP0010771_integument_phenotype0.92979153
81MP0000858_altered_metastatic_potential0.91322055
82MP0009703_decreased_birth_body0.90885814
83MP0004858_abnormal_nervous_system0.89089383
84MP0001661_extended_life_span0.89060252
85MP0009697_abnormal_copulation0.88618921
86MP0004133_heterotaxia0.88550572
87MP0003385_abnormal_body_wall0.87832932
88MP0000377_abnormal_hair_follicle0.86631126
89MP0005397_hematopoietic_system_phenotyp0.86474203
90MP0001545_abnormal_hematopoietic_system0.86474203
91MP0001243_abnormal_dermal_layer0.86401491
92MP0000467_abnormal_esophagus_morphology0.86031907
93MP0008438_abnormal_cutaneous_collagen0.85440994
94MP0005621_abnormal_cell_physiology0.85250269
95MP0004264_abnormal_extraembryonic_tissu0.85174039
96MP0005384_cellular_phenotype0.84739128
97MP0003115_abnormal_respiratory_system0.84726699
98MP0003950_abnormal_plasma_membrane0.84597513
99MP0000358_abnormal_cell_content/0.84248316
100MP0009931_abnormal_skin_appearance0.83885551
101MP0010678_abnormal_skin_adnexa0.82797634
102MP0002210_abnormal_sex_determination0.82736762
103MP0000703_abnormal_thymus_morphology0.82333705
104MP0009333_abnormal_splenocyte_physiolog0.81167689
105MP0004782_abnormal_surfactant_physiolog0.79406754
106MP0001145_abnormal_male_reproductive0.79372483
107MP0000477_abnormal_intestine_morphology0.78124191
108MP0001881_abnormal_mammary_gland0.78092089
109MP0004185_abnormal_adipocyte_glucose0.75734520
110MP0003283_abnormal_digestive_organ0.75553816
111MP0001727_abnormal_embryo_implantation0.75275033
112MP0002925_abnormal_cardiovascular_devel0.74954242
113MP0000432_abnormal_head_morphology0.73227979
114MP0001286_abnormal_eye_development0.73225659
115MP0003221_abnormal_cardiomyocyte_apopto0.73164984
116MP0001853_heart_inflammation0.73009824
117MP0005501_abnormal_skin_physiology0.72719952
118MP0002089_abnormal_postnatal_growth/wei0.72244401
119MP0003935_abnormal_craniofacial_develop0.71436864
120MP0003448_altered_tumor_morphology0.70601113
121MP0006035_abnormal_mitochondrial_morpho0.69836552
122MP0000750_abnormal_muscle_regeneration0.66439703
123MP0001340_abnormal_eyelid_morphology0.66115449
124MP0008770_decreased_survivor_rate0.65902191
125MP0002722_abnormal_immune_system0.63615264
126MP0000371_diluted_coat_color0.63362594
127MP0002282_abnormal_trachea_morphology0.60811184
128MP0003861_abnormal_nervous_system0.60776484
129MP0000653_abnormal_sex_gland0.60400384
130MP0003453_abnormal_keratinocyte_physiol0.57686550
131MP0004233_abnormal_muscle_weight0.57392141
132MP0005367_renal/urinary_system_phenotyp0.57244172
133MP0000516_abnormal_urinary_system0.57244172
134MP0002398_abnormal_bone_marrow0.57095821
135MP0005187_abnormal_penis_morphology0.56747129
136MP0000627_abnormal_mammary_gland0.56734478

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.35545295
2Selective tooth agenesis (HP:0001592)3.71275934
3Colon cancer (HP:0003003)3.64050119
4Birth length less than 3rd percentile (HP:0003561)3.44585896
5Abnormality of nail color (HP:0100643)3.38288717
6Reticulocytopenia (HP:0001896)3.32857918
7Medulloblastoma (HP:0002885)3.32028405
8Abnormality of the astrocytes (HP:0100707)3.23643077
9Astrocytoma (HP:0009592)3.23643077
10Progressive muscle weakness (HP:0003323)3.15318753
11Agnosia (HP:0010524)3.07215843
12Microvesicular hepatic steatosis (HP:0001414)2.93084004
13Breast hypoplasia (HP:0003187)2.86088265
14Abnormality of the anterior horn cell (HP:0006802)2.79098998
15Degeneration of anterior horn cells (HP:0002398)2.79098998
16Rhabdomyosarcoma (HP:0002859)2.75881089
17Glioma (HP:0009733)2.72296695
18Deviation of the thumb (HP:0009603)2.68469320
19Proximal placement of thumb (HP:0009623)2.66483283
20Premature rupture of membranes (HP:0001788)2.61717847
21Biliary tract neoplasm (HP:0100574)2.58913989
22Entropion (HP:0000621)2.58801760
23Neoplasm of the pancreas (HP:0002894)2.55800118
24Oral leukoplakia (HP:0002745)2.51951954
25Abnormality of the labia minora (HP:0012880)2.50999610
26Missing ribs (HP:0000921)2.50174984
27Short 4th metacarpal (HP:0010044)2.50089013
28Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.50089013
29Patellar aplasia (HP:0006443)2.49911528
30Basal cell carcinoma (HP:0002671)2.47584504
31Neoplasm of the oral cavity (HP:0100649)2.47039778
32Abnormality of cells of the erythroid lineage (HP:0012130)2.44199071
33Achilles tendon contracture (HP:0001771)2.42723721
34Sparse lateral eyebrow (HP:0005338)2.40504352
35Aplasia/Hypoplasia of the patella (HP:0006498)2.39898580
36Vertebral compression fractures (HP:0002953)2.39371693
37Increased nuchal translucency (HP:0010880)2.37988652
38Chromsome breakage (HP:0040012)2.35279199
39Progressive external ophthalmoplegia (HP:0000590)2.35046261
40Poikiloderma (HP:0001029)2.33484892
41Short nail (HP:0001799)2.32977376
42Gastrointestinal carcinoma (HP:0002672)2.32662975
43Malignant gastrointestinal tract tumors (HP:0006749)2.32662975
44Abnormal trabecular bone morphology (HP:0100671)2.29606166
45Abnormality of the distal phalanges of the toes (HP:0010182)2.29569622
46Ulnar bowing (HP:0003031)2.29440594
47Syringomyelia (HP:0003396)2.29064274
48Spinal cord lesions (HP:0100561)2.29064274
49Absent radius (HP:0003974)2.28584822
50Neoplasm of striated muscle (HP:0009728)2.23909320
51Trismus (HP:0000211)2.20341248
52Insomnia (HP:0100785)2.20296547
53Carpal bone hypoplasia (HP:0001498)2.20162084
54Chromosomal breakage induced by crosslinking agents (HP:0003221)2.18953518
55Abnormality of the calcaneus (HP:0008364)2.17910241
56Distal lower limb amyotrophy (HP:0008944)2.16043960
57Natal tooth (HP:0000695)2.15588261
58Atresia of the external auditory canal (HP:0000413)2.14216226
59Ragged-red muscle fibers (HP:0003200)2.13845135
60Aplasia/hypoplasia of the humerus (HP:0006507)2.13595953
61Angiofibromas (HP:0010615)2.13501652
62Adenoma sebaceum (HP:0009720)2.13501652
63Ankle contracture (HP:0006466)2.13132586
64Spastic diplegia (HP:0001264)2.12111214
65Absent forearm bone (HP:0003953)2.11530701
66Aplasia involving forearm bones (HP:0009822)2.11530701
67Abnormality of chromosome stability (HP:0003220)2.10516120
68Abnormality of the distal phalanx of the thumb (HP:0009617)2.10291287
69Absent thumb (HP:0009777)2.09987601
70Pelvic girdle muscle weakness (HP:0003749)2.09924126
71Amaurosis fugax (HP:0100576)2.09709537
72Multiple enchondromatosis (HP:0005701)2.08301843
73Abnormal number of erythroid precursors (HP:0012131)2.06145752
7411 pairs of ribs (HP:0000878)2.05821274
75Aplasia/Hypoplasia of the sacrum (HP:0008517)2.04166771
76Impulsivity (HP:0100710)2.03978125
77Ovarian neoplasm (HP:0100615)2.01686058
78Rough bone trabeculation (HP:0100670)2.00830324
79Abnormal number of incisors (HP:0011064)1.99311365
80Abnormality of the Achilles tendon (HP:0005109)1.99095438
81Meckel diverticulum (HP:0002245)1.99090082
82Cortical dysplasia (HP:0002539)1.93991761
83Short humerus (HP:0005792)1.93932547
84Abnormality of the umbilical cord (HP:0010881)1.93164332
85High pitched voice (HP:0001620)1.93066790
86Hyperacusis (HP:0010780)1.92910641
87Abnormality of the 4th metacarpal (HP:0010012)1.92882896
88Long palpebral fissure (HP:0000637)1.92854384
89Cutaneous melanoma (HP:0012056)1.90836491
90Cafe-au-lait spot (HP:0000957)1.90668249
91Ankyloglossia (HP:0010296)1.89705730
92Renal duplication (HP:0000075)1.89350073
93Abnormality of oral frenula (HP:0000190)1.88672170
94High anterior hairline (HP:0009890)1.88594938
95Abnormality of the ileum (HP:0001549)1.88336226
96Myelodysplasia (HP:0002863)1.87667487
97Prominent nose (HP:0000448)1.87338078
98Overriding aorta (HP:0002623)1.85447585
99Tracheoesophageal fistula (HP:0002575)1.85291831
100Pallor (HP:0000980)1.84914007
101Orthostatic hypotension (HP:0001278)1.84674627
102Uterine neoplasm (HP:0010784)1.84534801
103Neoplasm of the colon (HP:0100273)1.84208757
104Slender long bone (HP:0003100)1.83798178
105Flat acetabular roof (HP:0003180)1.83714936
106Osteolytic defects of the hand bones (HP:0009699)1.83140470
107Osteolytic defects of the phalanges of the hand (HP:0009771)1.83140470
108Protrusio acetabuli (HP:0003179)1.82700916
109Overlapping toe (HP:0001845)1.82454062
110Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.82339321
111Spinal muscular atrophy (HP:0007269)1.81772241
112Pseudobulbar signs (HP:0002200)1.80810631
113Increased density of long bones (HP:0006392)1.80742101
114Esophageal atresia (HP:0002032)1.80739032
115Premature ovarian failure (HP:0008209)1.80621924
116Macrocytic anemia (HP:0001972)1.80000665
117Shallow orbits (HP:0000586)1.79949827
118Ridged nail (HP:0001807)1.79356562
119Ectopic kidney (HP:0000086)1.78753208
120Abnormality of the preputium (HP:0100587)1.78544859
121Intestinal polyp (HP:0005266)1.77995714
122Abnormality of abdominal situs (HP:0011620)1.77900152
123Abdominal situs inversus (HP:0003363)1.77900152
124Elbow flexion contracture (HP:0002987)1.77559346
125Shoulder girdle muscle weakness (HP:0003547)1.77374304
126Duodenal stenosis (HP:0100867)1.75965693
127Small intestinal stenosis (HP:0012848)1.75965693
128Freckling (HP:0001480)1.75656178
129Upper limb muscle weakness (HP:0003484)1.75318048
130Squamous cell carcinoma (HP:0002860)1.75125996
131Atrophy/Degeneration involving motor neurons (HP:0007373)1.75084962
132Metaphyseal cupping (HP:0003021)1.74829945
133Glossoptosis (HP:0000162)1.74656853
134Neoplasm of the rectum (HP:0100743)1.74279412
135Facial hemangioma (HP:0000329)1.74187497
136Aplasia/Hypoplasia of the uvula (HP:0010293)1.74001661
137Asymmetry of the thorax (HP:0001555)1.73877001
138Deep philtrum (HP:0002002)1.73640955
139Facial cleft (HP:0002006)1.73502020
140Intestinal polyposis (HP:0200008)1.73188638
141Broad distal phalanx of finger (HP:0009836)1.71455917
142Aplasia/Hypoplasia of the sternum (HP:0006714)1.69545559
143Nail dystrophy (HP:0008404)1.68923766
144Reduced subcutaneous adipose tissue (HP:0003758)1.68605110
145Insidious onset (HP:0003587)1.67773876
146Termporal pattern (HP:0011008)1.67773876
147Ureteral duplication (HP:0000073)1.63981960
148Upper motor neuron abnormality (HP:0002127)1.63200292
149Thick nail (HP:0001805)1.63107272
150Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.62773959
151Broad face (HP:0000283)1.62038011
152Duplication of thumb phalanx (HP:0009942)1.59818303
153Fasciculations (HP:0002380)1.58619304
154Abnormalities of placenta or umbilical cord (HP:0001194)1.56609328
155Abnormality of the fetal cardiovascular system (HP:0010948)1.54371634
156Abnormal umbilical cord blood vessels (HP:0011403)1.54371634
157Single umbilical artery (HP:0001195)1.54371634
158Abnormality of reticulocytes (HP:0004312)1.54237313
159Advanced eruption of teeth (HP:0006288)1.53862316
160Lower limb amyotrophy (HP:0007210)1.53210910
161Abnormal autonomic nervous system physiology (HP:0012332)1.52342224
162Spina bifida occulta (HP:0003298)1.51114180
163Congenital ichthyosiform erythroderma (HP:0007431)1.50748431
164Elfin facies (HP:0004428)1.50482563
165Fragile nails (HP:0001808)1.50057492
166Difficulty climbing stairs (HP:0003551)1.49993614
167Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.49600912
168Abnormality of the hip-girdle musculature (HP:0001445)1.48422913
169Abnormality of the musculature of the pelvis (HP:0001469)1.48422913
170Abnormal ossification of hand bones (HP:0005921)1.47907350
171Premature graying of hair (HP:0002216)1.46576343
172Onycholysis (HP:0001806)1.46276703

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.71821241
2WEE13.51494956
3SMG13.35532074
4BUB13.33920906
5EEF2K2.73924719
6NEK22.62146751
7EPHA22.53433485
8IRAK32.51989263
9NEK12.48834581
10TLK12.46066385
11CDK122.42409535
12RPS6KB22.35373178
13PKN22.32012957
14SCYL22.22976698
15TSSK62.21623590
16PBK2.13730528
17TTK2.09752623
18TESK22.08548961
19PASK2.07137911
20SRPK12.04414564
21EIF2AK11.89514808
22VRK21.86297777
23MAP3K101.75586848
24ACVR1B1.65456609
25MAP3K81.64629301
26PAK41.64315953
27PLK11.58828492
28TRIB31.56741532
29TAF11.55553828
30MKNK11.54173423
31CDK71.54165184
32AURKB1.51008010
33ATR1.50168209
34TGFBR11.43198453
35CDK41.43151211
36RPS6KA41.42574758
37STK101.33769951
38PRPF4B1.31965664
39ZAK1.31508459
40ALK1.30804234
41NME21.30366325
42BRSK21.28621856
43FLT31.28445271
44PLK31.28209333
45DYRK31.27769471
46MST1R1.21927970
47PIM21.20856364
48ERBB41.20783466
49PLK41.20247367
50CDK61.18759258
51CHEK21.16683353
52CHEK11.16364054
53LRRK21.16190730
54TESK11.14948996
55LATS11.13029841
56VRK11.12581314
57EIF2AK31.10747114
58TTN1.07048711
59AURKA1.04053267
60BRD41.02886423
61STK41.01744832
62SIK10.99437026
63STK160.96174351
64PIM10.94891399
65MTOR0.92381929
66MKNK20.90305758
67PDK20.87292502
68LATS20.86240532
69CDK20.85094342
70ABL20.84975826
71MAPKAPK30.84880291
72PAK20.81915159
73ATM0.81661967
74CDK80.78329452
75PTK60.77605512
76STK30.77559137
77PDGFRA0.71276411
78PAK10.68278214
79BRSK10.66768710
80FGFR10.62784574
81MAP3K140.62678625
82NEK90.62398852
83MET0.61948719
84BRAF0.61294889
85MELK0.59526777
86PTK20.59438006
87LIMK10.58777466
88MOS0.58758792
89CDK10.58316603
90ARAF0.57074241
91CSNK2A20.55375461
92RPS6KA50.53548240
93PRKCI0.53335259
94MAP2K30.52606885
95AKT20.52566691
96CAMK1D0.51730231
97PNCK0.48519252
98EIF2AK20.47894174
99CLK10.47516681
100MAPK110.46908835
101CSNK1A1L0.46846849
102CSNK1E0.46473112
103FGFR40.44427330
104ILK0.43234259
105BMX0.41149218
106KSR20.39606525
107PRKDC0.38962560
108RPS6KL10.38469032
109RPS6KC10.38469032
110CSNK1D0.38021041
111CSNK2A10.37313246
112MAP2K70.37151011
113MAP3K30.36916778
114CDK11A0.36078556
115KDR0.34447683
116MAP3K60.34426964
117RIPK10.32527024
118MAP3K110.30723273
119CDK90.29898256
120DDR20.29570436
121ICK0.27401667
122MAPK140.26932660
123STK38L0.26581053
124MAP2K20.26523920
125KSR10.26160482
126AKT10.25736639
127RPS6KA10.25455166
128TAOK20.23529671
129GRK60.22892732
130DAPK30.22778355
131MAPK10.21485035
132DYRK1B0.20193861

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.42775809
2Mismatch repair_Homo sapiens_hsa034303.85251626
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.51245770
4Spliceosome_Homo sapiens_hsa030403.24061396
5* RNA transport_Homo sapiens_hsa030133.21649893
6One carbon pool by folate_Homo sapiens_hsa006703.16822570
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.90270678
8Cell cycle_Homo sapiens_hsa041102.74055953
9Ribosome_Homo sapiens_hsa030102.64446876
10Base excision repair_Homo sapiens_hsa034102.55266627
11Nucleotide excision repair_Homo sapiens_hsa034202.51446711
12Systemic lupus erythematosus_Homo sapiens_hsa053222.47496130
13Homologous recombination_Homo sapiens_hsa034402.18589794
14Proteasome_Homo sapiens_hsa030502.12376014
15RNA polymerase_Homo sapiens_hsa030202.10331025
16mRNA surveillance pathway_Homo sapiens_hsa030151.90518140
17p53 signaling pathway_Homo sapiens_hsa041151.77179491
18Pyrimidine metabolism_Homo sapiens_hsa002401.74657912
19Non-homologous end-joining_Homo sapiens_hsa034501.69408513
20Fanconi anemia pathway_Homo sapiens_hsa034601.68748263
21Viral carcinogenesis_Homo sapiens_hsa052031.59542220
22Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.52754353
23RNA degradation_Homo sapiens_hsa030181.50811395
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.27495402
25Selenocompound metabolism_Homo sapiens_hsa004501.23555814
26Basal transcription factors_Homo sapiens_hsa030221.22360095
27Epstein-Barr virus infection_Homo sapiens_hsa051691.20599339
28MicroRNAs in cancer_Homo sapiens_hsa052061.16618557
29Alcoholism_Homo sapiens_hsa050341.10992654
30Antigen processing and presentation_Homo sapiens_hsa046121.10559160
31Small cell lung cancer_Homo sapiens_hsa052221.10285763
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.08031329
33Biosynthesis of amino acids_Homo sapiens_hsa012301.07299865
34Other glycan degradation_Homo sapiens_hsa005111.03148346
35HTLV-I infection_Homo sapiens_hsa051661.01625911
36Galactose metabolism_Homo sapiens_hsa000520.99070485
37Oocyte meiosis_Homo sapiens_hsa041140.95117704
38Hippo signaling pathway_Homo sapiens_hsa043900.92760433
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92609842
40Chronic myeloid leukemia_Homo sapiens_hsa052200.91209743
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90829782
42Herpes simplex infection_Homo sapiens_hsa051680.88994687
43Thyroid cancer_Homo sapiens_hsa052160.88766790
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.85512149
45Bladder cancer_Homo sapiens_hsa052190.84634918
46Colorectal cancer_Homo sapiens_hsa052100.83374733
47Central carbon metabolism in cancer_Homo sapiens_hsa052300.82562638
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80859741
49Legionellosis_Homo sapiens_hsa051340.80791787
50Pentose phosphate pathway_Homo sapiens_hsa000300.79484219
51Transcriptional misregulation in cancer_Homo sapiens_hsa052020.79192392
52Basal cell carcinoma_Homo sapiens_hsa052170.79014219
53Cyanoamino acid metabolism_Homo sapiens_hsa004600.76664942
54TGF-beta signaling pathway_Homo sapiens_hsa043500.76086710
55Adherens junction_Homo sapiens_hsa045200.75422797
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.74937923
57mTOR signaling pathway_Homo sapiens_hsa041500.74460293
58Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72307402
59Purine metabolism_Homo sapiens_hsa002300.71175928
602-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.70712151
61Notch signaling pathway_Homo sapiens_hsa043300.70209050
62Apoptosis_Homo sapiens_hsa042100.70131935
63Prion diseases_Homo sapiens_hsa050200.66242301
64RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64801899
65Salmonella infection_Homo sapiens_hsa051320.63252095
66Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62235890
67Proteoglycans in cancer_Homo sapiens_hsa052050.60764829
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60545921
69Carbon metabolism_Homo sapiens_hsa012000.60259349
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.59837075
71Pyruvate metabolism_Homo sapiens_hsa006200.58049585
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.58021952
73Vibrio cholerae infection_Homo sapiens_hsa051100.56956680
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55956448
75Viral myocarditis_Homo sapiens_hsa054160.55214489
76Shigellosis_Homo sapiens_hsa051310.51275915
77Hepatitis B_Homo sapiens_hsa051610.50620228
78Lysine degradation_Homo sapiens_hsa003100.50021656
79HIF-1 signaling pathway_Homo sapiens_hsa040660.49959636
80Folate biosynthesis_Homo sapiens_hsa007900.49684002
81Endometrial cancer_Homo sapiens_hsa052130.47556197
82Tight junction_Homo sapiens_hsa045300.46536897
83Sulfur relay system_Homo sapiens_hsa041220.46526963
84Hepatitis C_Homo sapiens_hsa051600.46258173
85Hedgehog signaling pathway_Homo sapiens_hsa043400.45833714
86Pathways in cancer_Homo sapiens_hsa052000.45509751
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45351178
88VEGF signaling pathway_Homo sapiens_hsa043700.44689050
89Non-small cell lung cancer_Homo sapiens_hsa052230.43966323
90ErbB signaling pathway_Homo sapiens_hsa040120.43963920
91Acute myeloid leukemia_Homo sapiens_hsa052210.42726856
92Prostate cancer_Homo sapiens_hsa052150.42337319
93Renal cell carcinoma_Homo sapiens_hsa052110.41701445
94Glioma_Homo sapiens_hsa052140.40245234
95N-Glycan biosynthesis_Homo sapiens_hsa005100.37536915
96Pancreatic cancer_Homo sapiens_hsa052120.37148890
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.36366468
98Lysosome_Homo sapiens_hsa041420.36337729
99Fatty acid elongation_Homo sapiens_hsa000620.35179209
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.34833340
101Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34737112
102Focal adhesion_Homo sapiens_hsa045100.33576938
103Renin-angiotensin system_Homo sapiens_hsa046140.32404401
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32280466
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29939732
106Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.29326434
107Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29211374
108Influenza A_Homo sapiens_hsa051640.29113885
109Melanoma_Homo sapiens_hsa052180.28579649
110Measles_Homo sapiens_hsa051620.28260032
111Glutathione metabolism_Homo sapiens_hsa004800.27865700
112NF-kappa B signaling pathway_Homo sapiens_hsa040640.26655949
113Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26349347
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.26061422
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.26057848
116ECM-receptor interaction_Homo sapiens_hsa045120.24272880
117Toxoplasmosis_Homo sapiens_hsa051450.22898296
118FoxO signaling pathway_Homo sapiens_hsa040680.22879015
119AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.22778629
120Fructose and mannose metabolism_Homo sapiens_hsa000510.21696091

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