

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.42239255 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.42239255 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.40429032 |
| 4 | sequestering of actin monomers (GO:0042989) | 5.05344242 |
| 5 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.70420081 |
| 6 | protein neddylation (GO:0045116) | 4.42064454 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.41808274 |
| 8 | DNA deamination (GO:0045006) | 4.17082190 |
| 9 | actin nucleation (GO:0045010) | 4.14409120 |
| 10 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.90502136 |
| 11 | cytidine deamination (GO:0009972) | 3.87035701 |
| 12 | cytidine metabolic process (GO:0046087) | 3.87035701 |
| 13 | cytidine catabolic process (GO:0006216) | 3.87035701 |
| 14 | respiratory electron transport chain (GO:0022904) | 3.74569120 |
| 15 | base-excision repair, AP site formation (GO:0006285) | 3.74007023 |
| 16 | electron transport chain (GO:0022900) | 3.71623569 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.69851287 |
| 18 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.68851267 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 3.66950899 |
| 20 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.63064363 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.61728835 |
| 22 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.56670064 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.52845693 |
| 24 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.50766540 |
| 25 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.50766540 |
| 26 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.50307460 |
| 27 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.50307460 |
| 28 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.50307460 |
| 29 | mast cell activation (GO:0045576) | 3.48567507 |
| 30 | proteasome assembly (GO:0043248) | 3.46721999 |
| 31 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.45687087 |
| 32 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.43736692 |
| 33 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.43085089 |
| 34 | positive regulation of lamellipodium assembly (GO:0010592) | 3.38365408 |
| 35 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.37921085 |
| 36 | protein-cofactor linkage (GO:0018065) | 3.37307296 |
| 37 | immunoglobulin mediated immune response (GO:0016064) | 3.37091125 |
| 38 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.36808371 |
| 39 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.36808371 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35343778 |
| 41 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35343778 |
| 42 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.33266047 |
| 43 | deoxyribonucleotide catabolic process (GO:0009264) | 3.32575503 |
| 44 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.32337411 |
| 45 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.32325457 |
| 46 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.29525226 |
| 47 | deoxyribose phosphate catabolic process (GO:0046386) | 3.28603119 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.27457358 |
| 49 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.22814315 |
| 50 | termination of RNA polymerase III transcription (GO:0006386) | 3.22814315 |
| 51 | autophagic vacuole fusion (GO:0000046) | 3.18507658 |
| 52 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.17376951 |
| 53 | regulation of cilium movement (GO:0003352) | 3.16584786 |
| 54 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.16283373 |
| 55 | negative regulation of ligase activity (GO:0051352) | 3.16283373 |
| 56 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.15299637 |
| 57 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.14428640 |
| 58 | ribosomal small subunit assembly (GO:0000028) | 3.10284216 |
| 59 | protein deneddylation (GO:0000338) | 3.08607082 |
| 60 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.07250542 |
| 61 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.05657894 |
| 62 | adenosine metabolic process (GO:0046085) | 3.03899105 |
| 63 | neutrophil activation involved in immune response (GO:0002283) | 3.02240560 |
| 64 | S-adenosylmethionine metabolic process (GO:0046500) | 3.02071342 |
| 65 | branched-chain amino acid catabolic process (GO:0009083) | 3.01931450 |
| 66 | cullin deneddylation (GO:0010388) | 3.01085111 |
| 67 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.99670187 |
| 68 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.99547555 |
| 69 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.95888591 |
| 70 | regulation of cellular amine metabolic process (GO:0033238) | 2.95588089 |
| 71 | cytochrome complex assembly (GO:0017004) | 2.93636694 |
| 72 | sleep (GO:0030431) | 2.93586757 |
| 73 | hydrogen ion transmembrane transport (GO:1902600) | 2.92725610 |
| 74 | positive regulation of ligase activity (GO:0051351) | 2.91485871 |
| 75 | negative regulation of T cell apoptotic process (GO:0070233) | 2.91403670 |
| 76 | ATP biosynthetic process (GO:0006754) | 2.90833261 |
| 77 | mast cell activation involved in immune response (GO:0002279) | 2.90549866 |
| 78 | mast cell degranulation (GO:0043303) | 2.90549866 |
| 79 | negative regulation of heart rate (GO:0010459) | 2.89798581 |
| 80 | protein prenylation (GO:0018342) | 2.86284487 |
| 81 | prenylation (GO:0097354) | 2.86284487 |
| 82 | B cell mediated immunity (GO:0019724) | 2.85256826 |
| 83 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.81762664 |
| 84 | protein complex biogenesis (GO:0070271) | 2.79144078 |
| 85 | deoxyribose phosphate metabolic process (GO:0019692) | 2.77375365 |
| 86 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.75555606 |
| 87 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.75192798 |
| 88 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.75176709 |
| 89 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.73637325 |
| 90 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.73290150 |
| 91 | organic cation transport (GO:0015695) | 2.71302623 |
| 92 | proton transport (GO:0015992) | 2.70861940 |
| 93 | hydrogen transport (GO:0006818) | 2.68786515 |
| 94 | positive thymic T cell selection (GO:0045059) | 2.66783299 |
| 95 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.66213066 |
| 96 | respiratory chain complex IV assembly (GO:0008535) | 2.65973553 |
| 97 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.65363492 |
| 98 | metallo-sulfur cluster assembly (GO:0031163) | 2.65329697 |
| 99 | iron-sulfur cluster assembly (GO:0016226) | 2.65329697 |
| 100 | positive regulation of cell cycle arrest (GO:0071158) | 2.64327853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.16606953 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.34617703 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.27943521 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.15648131 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.09135066 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.00754096 |
| 7 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.76499022 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.50751558 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.09804817 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.95088150 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.90218112 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.80996157 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78317844 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.48108902 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.41211981 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.36378154 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.33671094 |
| 18 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.33241580 |
| 19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.29472799 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.26892198 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.07733129 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.04674262 |
| 23 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.94807767 |
| 24 | VDR_22108803_ChIP-Seq_LS180_Human | 1.87981188 |
| 25 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.85705500 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.84973908 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.81857730 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.79374682 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.76200097 |
| 30 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.75969959 |
| 31 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.75894423 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.73747652 |
| 33 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67894476 |
| 34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66795505 |
| 35 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.65277669 |
| 36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.61827588 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.59931709 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.50176546 |
| 39 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.48668073 |
| 40 | MYB_26560356_Chip-Seq_TH2_Human | 1.47788374 |
| 41 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.46742833 |
| 42 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.42749337 |
| 43 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.37293282 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.35979836 |
| 45 | GATA3_26560356_Chip-Seq_TH2_Human | 1.30858670 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.29999146 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27644255 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.27534560 |
| 49 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26608997 |
| 50 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.24460820 |
| 51 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.24339601 |
| 52 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.23181612 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.23146208 |
| 54 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.21730751 |
| 55 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.20486936 |
| 56 | AR_20517297_ChIP-Seq_VCAP_Human | 1.20430177 |
| 57 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.19670892 |
| 58 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.17237191 |
| 59 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.16826731 |
| 60 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14994979 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14903351 |
| 62 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.13973907 |
| 63 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13942718 |
| 64 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.13709061 |
| 65 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.12645379 |
| 66 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11283905 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10503089 |
| 68 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08633618 |
| 69 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.07409617 |
| 70 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.06827136 |
| 71 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.04219929 |
| 72 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.03826443 |
| 73 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03637354 |
| 74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03637354 |
| 75 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03500567 |
| 76 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.02526015 |
| 77 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.01653312 |
| 78 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.01001488 |
| 79 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.98744789 |
| 80 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.98592713 |
| 81 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.97993778 |
| 82 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.94949787 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 0.94853840 |
| 84 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.94386978 |
| 85 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.93518796 |
| 86 | NCOR_22424771_ChIP-Seq_293T_Human | 0.93166007 |
| 87 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91729549 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.91580468 |
| 89 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.91337007 |
| 90 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.91180202 |
| 91 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.91061159 |
| 92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.90868245 |
| 93 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.90714920 |
| 94 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90644458 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.89138106 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.89138106 |
| 97 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.88917699 |
| 98 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.88417097 |
| 99 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.86174631 |
| 100 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.85827793 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.68157463 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.45738495 |
| 3 | MP0003724_increased_susceptibility_to | 3.36280987 |
| 4 | MP0003646_muscle_fatigue | 2.93410853 |
| 5 | MP0004147_increased_porphyrin_level | 2.68919872 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.65491676 |
| 7 | MP0002102_abnormal_ear_morphology | 2.64289163 |
| 8 | MP0009785_altered_susceptibility_to | 2.55212273 |
| 9 | MP0002876_abnormal_thyroid_physiology | 2.40794823 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.28637861 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.26981592 |
| 12 | MP0002148_abnormal_hypersensitivity_rea | 2.25373400 |
| 13 | MP0009764_decreased_sensitivity_to | 2.20076721 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 2.15850110 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 2.14143329 |
| 16 | MP0002166_altered_tumor_susceptibility | 2.06989408 |
| 17 | MP0005670_abnormal_white_adipose | 1.94623828 |
| 18 | MP0005075_abnormal_melanosome_morpholog | 1.89947809 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.89473768 |
| 20 | MP0001800_abnormal_humoral_immune | 1.82740095 |
| 21 | MP0003195_calcinosis | 1.74348944 |
| 22 | MP0001905_abnormal_dopamine_level | 1.72558660 |
| 23 | MP0002006_tumorigenesis | 1.67682919 |
| 24 | MP0008995_early_reproductive_senescence | 1.65926756 |
| 25 | MP0009379_abnormal_foot_pigmentation | 1.65025244 |
| 26 | MP0003806_abnormal_nucleotide_metabolis | 1.64461626 |
| 27 | MP0006292_abnormal_olfactory_placode | 1.64232398 |
| 28 | MP0003786_premature_aging | 1.62939271 |
| 29 | MP0002723_abnormal_immune_serum | 1.61442118 |
| 30 | MP0002420_abnormal_adaptive_immunity | 1.53579685 |
| 31 | MP0008058_abnormal_DNA_repair | 1.53277425 |
| 32 | MP0002736_abnormal_nociception_after | 1.52839985 |
| 33 | MP0001819_abnormal_immune_cell | 1.52042554 |
| 34 | MP0008872_abnormal_physiological_respon | 1.49346515 |
| 35 | MP0002452_abnormal_antigen_presenting | 1.48871292 |
| 36 | MP0010155_abnormal_intestine_physiology | 1.48797049 |
| 37 | MP0005253_abnormal_eye_physiology | 1.46811989 |
| 38 | MP0003693_abnormal_embryo_hatching | 1.41509310 |
| 39 | MP0005025_abnormal_response_to | 1.38847800 |
| 40 | MP0005551_abnormal_eye_electrophysiolog | 1.31579322 |
| 41 | MP0005645_abnormal_hypothalamus_physiol | 1.31184945 |
| 42 | MP0005367_renal/urinary_system_phenotyp | 1.28925287 |
| 43 | MP0000516_abnormal_urinary_system | 1.28925287 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.28270314 |
| 45 | MP0005464_abnormal_platelet_physiology | 1.27997632 |
| 46 | MP0001984_abnormal_olfaction | 1.26807055 |
| 47 | MP0002160_abnormal_reproductive_system | 1.22929786 |
| 48 | MP0001968_abnormal_touch/_nociception | 1.22071802 |
| 49 | MP0005646_abnormal_pituitary_gland | 1.21945148 |
| 50 | MP0001188_hyperpigmentation | 1.21691297 |
| 51 | MP0005389_reproductive_system_phenotype | 1.18163597 |
| 52 | MP0003718_maternal_effect | 1.16764838 |
| 53 | MP0008877_abnormal_DNA_methylation | 1.14974279 |
| 54 | MP0001764_abnormal_homeostasis | 1.13660420 |
| 55 | MP0001845_abnormal_inflammatory_respons | 1.12113410 |
| 56 | MP0003763_abnormal_thymus_physiology | 1.12022913 |
| 57 | MP0001919_abnormal_reproductive_system | 1.10647247 |
| 58 | MP0000689_abnormal_spleen_morphology | 1.09321410 |
| 59 | MP0002277_abnormal_respiratory_mucosa | 1.07355814 |
| 60 | MP0000716_abnormal_immune_system | 1.07011465 |
| 61 | MP0002419_abnormal_innate_immunity | 1.06754680 |
| 62 | MP0005332_abnormal_amino_acid | 1.05943396 |
| 63 | MP0002398_abnormal_bone_marrow | 1.04292162 |
| 64 | MP0003880_abnormal_central_pattern | 1.02426385 |
| 65 | MP0001542_abnormal_bone_strength | 1.02293142 |
| 66 | MP0005410_abnormal_fertilization | 1.02281170 |
| 67 | MP0002722_abnormal_immune_system | 0.99320012 |
| 68 | MP0002272_abnormal_nervous_system | 0.99257847 |
| 69 | MP0002163_abnormal_gland_morphology | 0.96373386 |
| 70 | MP0006082_CNS_inflammation | 0.96079421 |
| 71 | MP0006036_abnormal_mitochondrial_physio | 0.95964965 |
| 72 | MP0003638_abnormal_response/metabolism_ | 0.92435433 |
| 73 | MP0000372_irregular_coat_pigmentation | 0.91563265 |
| 74 | MP0003448_altered_tumor_morphology | 0.89994763 |
| 75 | MP0002429_abnormal_blood_cell | 0.89348493 |
| 76 | MP0001765_abnormal_ion_homeostasis | 0.88409249 |
| 77 | MP0000858_altered_metastatic_potential | 0.87337455 |
| 78 | MP0004885_abnormal_endolymph | 0.86465026 |
| 79 | MP0008469_abnormal_protein_level | 0.85652284 |
| 80 | MP0001661_extended_life_span | 0.85588180 |
| 81 | MP0001873_stomach_inflammation | 0.84758587 |
| 82 | MP0002138_abnormal_hepatobiliary_system | 0.84188186 |
| 83 | MP0009763_increased_sensitivity_to | 0.83645696 |
| 84 | MP0004957_abnormal_blastocyst_morpholog | 0.83308510 |
| 85 | MP0003075_altered_response_to | 0.81498336 |
| 86 | MP0004145_abnormal_muscle_electrophysio | 0.81237215 |
| 87 | MP0002019_abnormal_tumor_incidence | 0.80818381 |
| 88 | MP0000647_abnormal_sebaceous_gland | 0.79209712 |
| 89 | MP0005636_abnormal_mineral_homeostasis | 0.78952402 |
| 90 | MP0010368_abnormal_lymphatic_system | 0.78848396 |
| 91 | MP0003436_decreased_susceptibility_to | 0.78114791 |
| 92 | MP0009046_muscle_twitch | 0.77467613 |
| 93 | MP0010386_abnormal_urinary_bladder | 0.77029666 |
| 94 | MP0001970_abnormal_pain_threshold | 0.75779649 |
| 95 | MP0002938_white_spotting | 0.75682285 |
| 96 | MP0002405_respiratory_system_inflammati | 0.75678614 |
| 97 | MP0003283_abnormal_digestive_organ | 0.75015664 |
| 98 | MP0003252_abnormal_bile_duct | 0.74138688 |
| 99 | MP0003011_delayed_dark_adaptation | 0.73920038 |
| 100 | MP0001529_abnormal_vocalization | 0.73019070 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.90896474 |
| 2 | Hepatocellular necrosis (HP:0001404) | 4.47577183 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.39459368 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 4.25299152 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.01298690 |
| 6 | Hepatic necrosis (HP:0002605) | 4.00978970 |
| 7 | Decreased central vision (HP:0007663) | 3.97241617 |
| 8 | Increased CSF lactate (HP:0002490) | 3.92071763 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.85890006 |
| 10 | Acute encephalopathy (HP:0006846) | 3.69112783 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.54886053 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.51307224 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.45427138 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.44581009 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.13785631 |
| 16 | Severe combined immunodeficiency (HP:0004430) | 3.06960627 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.05328777 |
| 18 | Abnormality of the prostate (HP:0008775) | 3.05111683 |
| 19 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.97565746 |
| 20 | IgG deficiency (HP:0004315) | 2.96780996 |
| 21 | Cerebral edema (HP:0002181) | 2.93347150 |
| 22 | Lactic acidosis (HP:0003128) | 2.87756570 |
| 23 | Hyperglycinemia (HP:0002154) | 2.83876860 |
| 24 | Exertional dyspnea (HP:0002875) | 2.82728825 |
| 25 | Hypoproteinemia (HP:0003075) | 2.71627735 |
| 26 | Increased serum lactate (HP:0002151) | 2.70585809 |
| 27 | Pancytopenia (HP:0001876) | 2.68138104 |
| 28 | Type I transferrin isoform profile (HP:0003642) | 2.65382512 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.55356010 |
| 30 | Prostate neoplasm (HP:0100787) | 2.54898191 |
| 31 | Optic disc pallor (HP:0000543) | 2.51507548 |
| 32 | Methylmalonic acidemia (HP:0002912) | 2.51332119 |
| 33 | Autoimmune hemolytic anemia (HP:0001890) | 2.51161795 |
| 34 | Microretrognathia (HP:0000308) | 2.48833704 |
| 35 | Attenuation of retinal blood vessels (HP:0007843) | 2.47625113 |
| 36 | Abnormal protein glycosylation (HP:0012346) | 2.42117886 |
| 37 | Abnormal glycosylation (HP:0012345) | 2.42117886 |
| 38 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.42117886 |
| 39 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.42117886 |
| 40 | Tinnitus (HP:0000360) | 2.40017059 |
| 41 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.38435578 |
| 42 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.37289638 |
| 43 | Respiratory failure (HP:0002878) | 2.36844833 |
| 44 | Abnormal number of erythroid precursors (HP:0012131) | 2.35238895 |
| 45 | Combined immunodeficiency (HP:0005387) | 2.32398236 |
| 46 | Chronic sinusitis (HP:0011109) | 2.31613779 |
| 47 | Erythema (HP:0010783) | 2.30623294 |
| 48 | Congenital stationary night blindness (HP:0007642) | 2.30424733 |
| 49 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.25495485 |
| 50 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.25495485 |
| 51 | Pancreatic cysts (HP:0001737) | 2.25484249 |
| 52 | Abnormality of serum amino acid levels (HP:0003112) | 2.23934255 |
| 53 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.23574142 |
| 54 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.23496438 |
| 55 | Abnormality of glycine metabolism (HP:0010895) | 2.22128775 |
| 56 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.22128775 |
| 57 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.20775524 |
| 58 | Congenital, generalized hypertrichosis (HP:0004540) | 2.18536718 |
| 59 | Generalized aminoaciduria (HP:0002909) | 2.16449595 |
| 60 | Renal cortical cysts (HP:0000803) | 2.15272202 |
| 61 | Abolished electroretinogram (ERG) (HP:0000550) | 2.14745470 |
| 62 | Hyperammonemia (HP:0001987) | 2.14558150 |
| 63 | Abnormality of alanine metabolism (HP:0010916) | 2.14468989 |
| 64 | Hyperalaninemia (HP:0003348) | 2.14468989 |
| 65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.14468989 |
| 66 | True hermaphroditism (HP:0010459) | 2.12019327 |
| 67 | Lethargy (HP:0001254) | 2.11503240 |
| 68 | Leukodystrophy (HP:0002415) | 2.10713009 |
| 69 | Oral leukoplakia (HP:0002745) | 2.07922677 |
| 70 | Stenosis of the external auditory canal (HP:0000402) | 2.07540832 |
| 71 | Rectovaginal fistula (HP:0000143) | 2.07068986 |
| 72 | Rectal fistula (HP:0100590) | 2.07068986 |
| 73 | Short tibia (HP:0005736) | 2.06993889 |
| 74 | Thyroiditis (HP:0100646) | 2.04577736 |
| 75 | Alveolar cell carcinoma (HP:0006519) | 2.01715611 |
| 76 | Facial diplegia (HP:0001349) | 2.00122911 |
| 77 | Respiratory difficulties (HP:0002880) | 1.97565903 |
| 78 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.95604022 |
| 79 | Absent/shortened dynein arms (HP:0200106) | 1.95604022 |
| 80 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.95231219 |
| 81 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.95231219 |
| 82 | Agitation (HP:0000713) | 1.95083007 |
| 83 | CNS demyelination (HP:0007305) | 1.94894201 |
| 84 | Methylmalonic aciduria (HP:0012120) | 1.91902891 |
| 85 | Type 2 muscle fiber atrophy (HP:0003554) | 1.90863550 |
| 86 | Abnormality of eosinophils (HP:0001879) | 1.87055246 |
| 87 | Cerebral palsy (HP:0100021) | 1.86788130 |
| 88 | Type II lissencephaly (HP:0007260) | 1.86464867 |
| 89 | Abnormality of renal resorption (HP:0011038) | 1.85661984 |
| 90 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.85281313 |
| 91 | Exercise intolerance (HP:0003546) | 1.85041715 |
| 92 | Pancreatic fibrosis (HP:0100732) | 1.79145730 |
| 93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.79114506 |
| 94 | Spastic paraparesis (HP:0002313) | 1.78545478 |
| 95 | Glycosuria (HP:0003076) | 1.78073207 |
| 96 | Abnormality of urine glucose concentration (HP:0011016) | 1.78073207 |
| 97 | Abnormality of midbrain morphology (HP:0002418) | 1.75239362 |
| 98 | Molar tooth sign on MRI (HP:0002419) | 1.75239362 |
| 99 | IgM deficiency (HP:0002850) | 1.75173614 |
| 100 | Mesangial abnormality (HP:0001966) | 1.73617274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 3.84296662 |
| 2 | TLK1 | 3.79664052 |
| 3 | MAP4K2 | 3.42679468 |
| 4 | TIE1 | 3.38386651 |
| 5 | ZAK | 3.19873248 |
| 6 | KDR | 2.85303049 |
| 7 | NUAK1 | 2.83482338 |
| 8 | BCKDK | 2.75711618 |
| 9 | VRK2 | 2.75498579 |
| 10 | TAOK3 | 2.74559969 |
| 11 | TXK | 2.69607363 |
| 12 | CDK19 | 2.67814245 |
| 13 | BMPR2 | 2.45189810 |
| 14 | MAP3K12 | 2.39399079 |
| 15 | STK16 | 2.23034407 |
| 16 | EIF2AK3 | 1.68369902 |
| 17 | KIT | 1.66658618 |
| 18 | OXSR1 | 1.65350393 |
| 19 | GRK1 | 1.64373334 |
| 20 | VRK1 | 1.61498365 |
| 21 | BUB1 | 1.60788907 |
| 22 | SCYL2 | 1.58093576 |
| 23 | MAP4K1 | 1.55464319 |
| 24 | LIMK1 | 1.45324112 |
| 25 | CSF1R | 1.41818096 |
| 26 | TEC | 1.40425360 |
| 27 | PASK | 1.37498124 |
| 28 | TESK1 | 1.36264344 |
| 29 | ITK | 1.31992699 |
| 30 | FLT3 | 1.26675080 |
| 31 | ADRBK2 | 1.24921235 |
| 32 | IKBKE | 1.22526578 |
| 33 | DAPK1 | 1.18983112 |
| 34 | IKBKB | 1.14858204 |
| 35 | MYLK | 1.11447548 |
| 36 | CSNK1G3 | 1.08078766 |
| 37 | MST4 | 1.04387966 |
| 38 | ARAF | 0.99894440 |
| 39 | PIM2 | 0.95744276 |
| 40 | WNK4 | 0.90304691 |
| 41 | LYN | 0.89834955 |
| 42 | MAP2K7 | 0.87886754 |
| 43 | TAF1 | 0.87262396 |
| 44 | SYK | 0.87127699 |
| 45 | CSNK1G1 | 0.82272441 |
| 46 | NEK1 | 0.81667748 |
| 47 | FRK | 0.81312113 |
| 48 | CSNK1A1L | 0.81022795 |
| 49 | RPS6KA5 | 0.80431942 |
| 50 | MAP3K14 | 0.79623353 |
| 51 | PRKCQ | 0.74510477 |
| 52 | PIK3CA | 0.73531044 |
| 53 | CSNK1G2 | 0.72465055 |
| 54 | LCK | 0.71386801 |
| 55 | EPHA3 | 0.70849686 |
| 56 | DAPK3 | 0.69499863 |
| 57 | GRK6 | 0.65586975 |
| 58 | EIF2AK2 | 0.65364438 |
| 59 | BTK | 0.64563679 |
| 60 | MATK | 0.64410239 |
| 61 | MAPK13 | 0.64274678 |
| 62 | TBK1 | 0.64140646 |
| 63 | DYRK2 | 0.62195569 |
| 64 | GRK7 | 0.60915142 |
| 65 | ERBB3 | 0.60767833 |
| 66 | CAMKK2 | 0.60647139 |
| 67 | SRPK1 | 0.60071564 |
| 68 | MAP2K2 | 0.59203003 |
| 69 | ZAP70 | 0.56222537 |
| 70 | PLK4 | 0.56195887 |
| 71 | AURKA | 0.54588997 |
| 72 | LMTK2 | 0.49931150 |
| 73 | FES | 0.47716975 |
| 74 | AURKB | 0.45924340 |
| 75 | PHKG2 | 0.43927480 |
| 76 | PHKG1 | 0.43927480 |
| 77 | STK39 | 0.41956202 |
| 78 | INSRR | 0.41317986 |
| 79 | GRK5 | 0.40152650 |
| 80 | JAK3 | 0.39800957 |
| 81 | MAPKAPK5 | 0.38777582 |
| 82 | CDK8 | 0.38486546 |
| 83 | CSNK2A1 | 0.38259482 |
| 84 | PAK1 | 0.36681555 |
| 85 | ROCK1 | 0.36387497 |
| 86 | IGF1R | 0.35701280 |
| 87 | DAPK2 | 0.34900218 |
| 88 | PBK | 0.33484825 |
| 89 | TSSK6 | 0.29441413 |
| 90 | CAMKK1 | 0.27260246 |
| 91 | CCNB1 | 0.26762928 |
| 92 | ABL1 | 0.26107316 |
| 93 | STK10 | 0.25883916 |
| 94 | PLK1 | 0.25665947 |
| 95 | ADRBK1 | 0.24710597 |
| 96 | PRKCA | 0.23193805 |
| 97 | NME2 | 0.22902570 |
| 98 | MKNK1 | 0.21701674 |
| 99 | ATR | 0.20137763 |
| 100 | CSK | 0.19667514 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.41124025 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.56258089 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.30736859 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.29305495 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.26940737 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.10531720 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.88859389 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.70112945 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.61160667 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.41395114 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.22827436 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.13902564 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.10794753 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.08464082 |
| 15 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.06312492 |
| 16 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.87031832 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.80607629 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.64913486 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.64066065 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.58311005 |
| 21 | Viral myocarditis_Homo sapiens_hsa05416 | 1.55425623 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.43613296 |
| 23 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.37729986 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.34567922 |
| 25 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.34344091 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.32162743 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.31693133 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.30994319 |
| 29 | Protein export_Homo sapiens_hsa03060 | 1.29165696 |
| 30 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.25280276 |
| 31 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.24454145 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.22721272 |
| 33 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.18630330 |
| 34 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17212744 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16711470 |
| 36 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.14512769 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.12144739 |
| 38 | Leishmaniasis_Homo sapiens_hsa05140 | 1.06021639 |
| 39 | Homologous recombination_Homo sapiens_hsa03440 | 1.04267827 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.96819678 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.96167100 |
| 42 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.93908091 |
| 43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.93517178 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.92091475 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.90906136 |
| 46 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.89428125 |
| 47 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88206611 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 0.84430158 |
| 49 | DNA replication_Homo sapiens_hsa03030 | 0.82796803 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.82459031 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.81397929 |
| 52 | Mismatch repair_Homo sapiens_hsa03430 | 0.79589237 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73073608 |
| 54 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.69554909 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.66534206 |
| 56 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.66531179 |
| 57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.66367604 |
| 58 | Alcoholism_Homo sapiens_hsa05034 | 0.63342036 |
| 59 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.63254619 |
| 60 | Base excision repair_Homo sapiens_hsa03410 | 0.62177588 |
| 61 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62010124 |
| 62 | Salmonella infection_Homo sapiens_hsa05132 | 0.58975755 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.58274395 |
| 64 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.57999727 |
| 65 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56709542 |
| 66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.56014624 |
| 67 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54769770 |
| 68 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.53138036 |
| 69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52301988 |
| 70 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.51469757 |
| 71 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.50025019 |
| 72 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.49083726 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46540413 |
| 74 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.46181210 |
| 75 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46082517 |
| 76 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.45639341 |
| 77 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.44759827 |
| 78 | Phagosome_Homo sapiens_hsa04145 | 0.44590935 |
| 79 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42880593 |
| 80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.40672929 |
| 81 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.39636713 |
| 82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.39600941 |
| 83 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.39150367 |
| 84 | Legionellosis_Homo sapiens_hsa05134 | 0.38597924 |
| 85 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.37426596 |
| 86 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.36796306 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34456588 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32335866 |
| 89 | Influenza A_Homo sapiens_hsa05164 | 0.32035169 |
| 90 | Malaria_Homo sapiens_hsa05144 | 0.31588516 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.29136800 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28653707 |
| 93 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.27579573 |
| 94 | Tuberculosis_Homo sapiens_hsa05152 | 0.27225377 |
| 95 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.26732821 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.25401621 |
| 97 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.24821118 |
| 98 | Nicotine addiction_Homo sapiens_hsa05033 | 0.24664930 |
| 99 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.23684785 |
| 100 | Measles_Homo sapiens_hsa05162 | 0.22637694 |

