

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 5.82753347 |
| 2 | cytidine metabolic process (GO:0046087) | 5.82753347 |
| 3 | cytidine catabolic process (GO:0006216) | 5.82753347 |
| 4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.43709552 |
| 5 | proteasome assembly (GO:0043248) | 5.06191792 |
| 6 | DNA deamination (GO:0045006) | 4.92070458 |
| 7 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.84416126 |
| 8 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.84416126 |
| 9 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.82346391 |
| 10 | regulation of memory T cell differentiation (GO:0043380) | 4.67693322 |
| 11 | ubiquinone biosynthetic process (GO:0006744) | 4.14167899 |
| 12 | positive regulation of defense response to virus by host (GO:0002230) | 4.01228724 |
| 13 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.95547447 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.94381102 |
| 15 | rRNA modification (GO:0000154) | 3.93767407 |
| 16 | positive T cell selection (GO:0043368) | 3.77410359 |
| 17 | positive thymic T cell selection (GO:0045059) | 3.76453187 |
| 18 | positive regulation of B cell differentiation (GO:0045579) | 3.73968942 |
| 19 | purine nucleotide salvage (GO:0032261) | 3.72747552 |
| 20 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.70113761 |
| 21 | protein complex biogenesis (GO:0070271) | 3.65620790 |
| 22 | ubiquinone metabolic process (GO:0006743) | 3.65433403 |
| 23 | negative T cell selection (GO:0043383) | 3.63621319 |
| 24 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.63463075 |
| 25 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.63463075 |
| 26 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.63463075 |
| 27 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.62586020 |
| 28 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.61873728 |
| 29 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.59381208 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.59381208 |
| 31 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.59226964 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.59226964 |
| 33 | rRNA catabolic process (GO:0016075) | 3.58710191 |
| 34 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.57831616 |
| 35 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.57831616 |
| 36 | regulation of chronic inflammatory response (GO:0002676) | 3.57084426 |
| 37 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.50243380 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.49131626 |
| 39 | NADH dehydrogenase complex assembly (GO:0010257) | 3.49131626 |
| 40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.49131626 |
| 41 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.48825896 |
| 42 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.46959385 |
| 43 | piRNA metabolic process (GO:0034587) | 3.45594948 |
| 44 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.38312031 |
| 45 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.34391738 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.33895208 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.33895208 |
| 48 | regulation of regulatory T cell differentiation (GO:0045589) | 3.31586420 |
| 49 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.27287993 |
| 50 | pseudouridine synthesis (GO:0001522) | 3.23815514 |
| 51 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.23076125 |
| 52 | quinone biosynthetic process (GO:1901663) | 3.21274509 |
| 53 | adenosine metabolic process (GO:0046085) | 3.20937382 |
| 54 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.16436382 |
| 55 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.15945072 |
| 56 | GPI anchor biosynthetic process (GO:0006506) | 3.13770147 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.12982080 |
| 58 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.12968427 |
| 59 | positive regulation of cell killing (GO:0031343) | 3.03170097 |
| 60 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.01848819 |
| 61 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.01292406 |
| 62 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.99525338 |
| 63 | viral mRNA export from host cell nucleus (GO:0046784) | 2.97341926 |
| 64 | nucleotide salvage (GO:0043173) | 2.95421421 |
| 65 | protein polyglutamylation (GO:0018095) | 2.95308204 |
| 66 | positive regulation of cell cycle arrest (GO:0071158) | 2.93062430 |
| 67 | regulation of cellular amine metabolic process (GO:0033238) | 2.89925950 |
| 68 | response to interferon-beta (GO:0035456) | 2.89889754 |
| 69 | electron transport chain (GO:0022900) | 2.88021062 |
| 70 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.87674484 |
| 71 | GPI anchor metabolic process (GO:0006505) | 2.87304495 |
| 72 | respiratory electron transport chain (GO:0022904) | 2.86517880 |
| 73 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.86460910 |
| 74 | ATP synthesis coupled proton transport (GO:0015986) | 2.86460910 |
| 75 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.85537646 |
| 76 | regulation of B cell differentiation (GO:0045577) | 2.84957670 |
| 77 | positive regulation of ligase activity (GO:0051351) | 2.84948548 |
| 78 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.83453537 |
| 79 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.82535638 |
| 80 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.82449731 |
| 81 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.77774882 |
| 82 | rRNA methylation (GO:0031167) | 2.76745052 |
| 83 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.76471610 |
| 84 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.75883163 |
| 85 | regulation of mitochondrial translation (GO:0070129) | 2.75274708 |
| 86 | negative regulation of oxidoreductase activity (GO:0051354) | 2.74805609 |
| 87 | regulation of cell killing (GO:0031341) | 2.73196981 |
| 88 | organelle disassembly (GO:1903008) | 2.72684185 |
| 89 | cytolysis (GO:0019835) | 2.72571433 |
| 90 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.72099857 |
| 91 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.72099857 |
| 92 | regulation of defense response to virus by host (GO:0050691) | 2.70945990 |
| 93 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.70504141 |
| 94 | regulation of uterine smooth muscle contraction (GO:0070472) | 2.69601606 |
| 95 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.69538452 |
| 96 | negative thymic T cell selection (GO:0045060) | 2.69301323 |
| 97 | nucleobase biosynthetic process (GO:0046112) | 2.67470519 |
| 98 | cellular response to interleukin-15 (GO:0071350) | 2.65737295 |
| 99 | DNA methylation involved in gamete generation (GO:0043046) | 2.65467093 |
| 100 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.64528236 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 7.22466207 |
| 2 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 4.73604266 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.42489884 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.41644957 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.40990129 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.35038515 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.01337321 |
| 8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.86573106 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.84336841 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.68019377 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.65293718 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.64659291 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.52458867 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.50532809 |
| 15 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.50177567 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.48991450 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.34741606 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.33804282 |
| 19 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.32263339 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.21978771 |
| 21 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.12691156 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.11998428 |
| 23 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.09607819 |
| 24 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.07169499 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06830808 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.97559277 |
| 27 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.96752704 |
| 28 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.90159969 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.89139640 |
| 30 | VDR_22108803_ChIP-Seq_LS180_Human | 1.88698749 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.87831890 |
| 32 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.81076286 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.75215029 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.74194526 |
| 35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.67576395 |
| 36 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.67075093 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64567116 |
| 38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.64456191 |
| 39 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.62845993 |
| 40 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62740260 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.62263754 |
| 42 | MYB_26560356_Chip-Seq_TH2_Human | 1.61645221 |
| 43 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.59996778 |
| 44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.56999163 |
| 45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.55488374 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.54188435 |
| 47 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.53603187 |
| 48 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.51795039 |
| 49 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.50749782 |
| 50 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.47310543 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.46117031 |
| 52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.42265574 |
| 53 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.41927547 |
| 54 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.41081364 |
| 55 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.40783419 |
| 56 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.39669194 |
| 57 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.38905840 |
| 58 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.37782088 |
| 59 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36952629 |
| 60 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.30561382 |
| 61 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.29470487 |
| 62 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.28299918 |
| 63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27101794 |
| 64 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.23063803 |
| 65 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.20574865 |
| 66 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.19636072 |
| 67 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.19182916 |
| 68 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.17506062 |
| 69 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.16381532 |
| 70 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.13924868 |
| 71 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12518827 |
| 72 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.10114272 |
| 73 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.08752620 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04197959 |
| 75 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.03481163 |
| 76 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.03420446 |
| 77 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.00610948 |
| 78 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99894191 |
| 79 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.99152213 |
| 80 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.99063209 |
| 81 | MYB_26560356_Chip-Seq_TH1_Human | 0.98819023 |
| 82 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.98697468 |
| 83 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.98393577 |
| 84 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97074514 |
| 85 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96986624 |
| 86 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95794065 |
| 87 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.94821054 |
| 88 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.93273008 |
| 89 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.91613761 |
| 90 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.89761718 |
| 91 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.89410986 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.89284763 |
| 93 | P300_27268052_Chip-Seq_Bcells_Human | 0.88921106 |
| 94 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.87784211 |
| 95 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.87784211 |
| 96 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.87431506 |
| 97 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.87293738 |
| 98 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.87198772 |
| 99 | AR_20517297_ChIP-Seq_VCAP_Human | 0.84818396 |
| 100 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84754316 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.51896896 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.64292972 |
| 3 | MP0009785_altered_susceptibility_to | 2.99615306 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.81141196 |
| 5 | MP0002254_reproductive_system_inflammat | 2.68056940 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.61178933 |
| 7 | MP0009333_abnormal_splenocyte_physiolog | 2.53423837 |
| 8 | MP0005646_abnormal_pituitary_gland | 2.52583390 |
| 9 | MP0003693_abnormal_embryo_hatching | 2.51405569 |
| 10 | MP0002822_catalepsy | 2.32041065 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.29186994 |
| 12 | MP0000685_abnormal_immune_system | 2.27362311 |
| 13 | MP0005389_reproductive_system_phenotype | 2.26105252 |
| 14 | MP0002160_abnormal_reproductive_system | 2.22483325 |
| 15 | MP0003763_abnormal_thymus_physiology | 2.15931290 |
| 16 | MP0004147_increased_porphyrin_level | 2.15023633 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 2.12209298 |
| 18 | MP0002006_tumorigenesis | 2.11384137 |
| 19 | MP0000372_irregular_coat_pigmentation | 2.05945336 |
| 20 | MP0010155_abnormal_intestine_physiology | 2.04950202 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 2.02718263 |
| 22 | MP0002166_altered_tumor_susceptibility | 2.02353900 |
| 23 | MP0005025_abnormal_response_to | 1.97680332 |
| 24 | MP0001919_abnormal_reproductive_system | 1.94967562 |
| 25 | MP0001800_abnormal_humoral_immune | 1.88971930 |
| 26 | MP0003436_decreased_susceptibility_to | 1.88382329 |
| 27 | MP0009764_decreased_sensitivity_to | 1.81931432 |
| 28 | MP0002723_abnormal_immune_serum | 1.79780588 |
| 29 | MP0000678_abnormal_parathyroid_gland | 1.75414531 |
| 30 | MP0005083_abnormal_biliary_tract | 1.67337523 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.66576628 |
| 32 | MP0002420_abnormal_adaptive_immunity | 1.63101460 |
| 33 | MP0001819_abnormal_immune_cell | 1.58938862 |
| 34 | MP0002736_abnormal_nociception_after | 1.58415760 |
| 35 | MP0000703_abnormal_thymus_morphology | 1.56614037 |
| 36 | MP0003724_increased_susceptibility_to | 1.47102480 |
| 37 | MP0002452_abnormal_antigen_presenting | 1.47072691 |
| 38 | MP0003123_paternal_imprinting | 1.47043839 |
| 39 | MP0002132_abnormal_respiratory_system | 1.44825926 |
| 40 | MP0000716_abnormal_immune_system | 1.43806237 |
| 41 | MP0001790_abnormal_immune_system | 1.43653044 |
| 42 | MP0005387_immune_system_phenotype | 1.43653044 |
| 43 | MP0002398_abnormal_bone_marrow | 1.39612942 |
| 44 | MP0001873_stomach_inflammation | 1.39237685 |
| 45 | MP0008875_abnormal_xenobiotic_pharmacok | 1.31981781 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.30501708 |
| 47 | MP0006082_CNS_inflammation | 1.30272896 |
| 48 | MP0008872_abnormal_physiological_respon | 1.28524644 |
| 49 | MP0002722_abnormal_immune_system | 1.28252000 |
| 50 | MP0006072_abnormal_retinal_apoptosis | 1.27824945 |
| 51 | MP0008469_abnormal_protein_level | 1.24725854 |
| 52 | MP0001845_abnormal_inflammatory_respons | 1.24362517 |
| 53 | MP0002405_respiratory_system_inflammati | 1.24058316 |
| 54 | MP0000689_abnormal_spleen_morphology | 1.23460436 |
| 55 | MP0000490_abnormal_crypts_of | 1.23017958 |
| 56 | MP0002429_abnormal_blood_cell | 1.21546426 |
| 57 | MP0002876_abnormal_thyroid_physiology | 1.20681392 |
| 58 | MP0002419_abnormal_innate_immunity | 1.18770704 |
| 59 | MP0003866_abnormal_defecation | 1.16465439 |
| 60 | MP0009765_abnormal_xenobiotic_induced | 1.15892119 |
| 61 | MP0005075_abnormal_melanosome_morpholog | 1.14375825 |
| 62 | MP0010094_abnormal_chromosome_stability | 1.10976165 |
| 63 | MP0001881_abnormal_mammary_gland | 1.10843135 |
| 64 | MP0003880_abnormal_central_pattern | 1.10400944 |
| 65 | MP0001501_abnormal_sleep_pattern | 1.09656307 |
| 66 | MP0009763_increased_sensitivity_to | 1.08671736 |
| 67 | MP0004947_skin_inflammation | 1.08071140 |
| 68 | MP0008058_abnormal_DNA_repair | 1.07107636 |
| 69 | MP0001905_abnormal_dopamine_level | 1.02884470 |
| 70 | MP0005410_abnormal_fertilization | 1.01669813 |
| 71 | MP0006035_abnormal_mitochondrial_morpho | 0.97076485 |
| 72 | MP0003011_delayed_dark_adaptation | 0.96039917 |
| 73 | MP0001533_abnormal_skeleton_physiology | 0.92040962 |
| 74 | MP0005084_abnormal_gallbladder_morpholo | 0.91935279 |
| 75 | MP0003718_maternal_effect | 0.91876831 |
| 76 | MP0003638_abnormal_response/metabolism_ | 0.91213228 |
| 77 | MP0003787_abnormal_imprinting | 0.90353517 |
| 78 | MP0002102_abnormal_ear_morphology | 0.90306537 |
| 79 | MP0006036_abnormal_mitochondrial_physio | 0.89407682 |
| 80 | MP0001119_abnormal_female_reproductive | 0.88715554 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.88647121 |
| 82 | MP0008877_abnormal_DNA_methylation | 0.87167357 |
| 83 | MP0005451_abnormal_body_composition | 0.86358118 |
| 84 | MP0002019_abnormal_tumor_incidence | 0.86271689 |
| 85 | MP0003077_abnormal_cell_cycle | 0.84257226 |
| 86 | MP0001243_abnormal_dermal_layer | 0.79024595 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.78809131 |
| 88 | MP0001529_abnormal_vocalization | 0.76311219 |
| 89 | MP0009697_abnormal_copulation | 0.75374747 |
| 90 | MP0009278_abnormal_bone_marrow | 0.75266540 |
| 91 | MP0000627_abnormal_mammary_gland | 0.74944204 |
| 92 | MP0003252_abnormal_bile_duct | 0.73092871 |
| 93 | MP0002277_abnormal_respiratory_mucosa | 0.73027434 |
| 94 | MP0008932_abnormal_embryonic_tissue | 0.71883977 |
| 95 | MP0004043_abnormal_pH_regulation | 0.71869064 |
| 96 | MP0000427_abnormal_hair_cycle | 0.71791496 |
| 97 | MP0003111_abnormal_nucleus_morphology | 0.71725698 |
| 98 | MP0005167_abnormal_blood-brain_barrier | 0.68698463 |
| 99 | MP0005085_abnormal_gallbladder_physiolo | 0.68353033 |
| 100 | MP0002933_joint_inflammation | 0.68315410 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.37219902 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.05356703 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.01499257 |
| 4 | Severe combined immunodeficiency (HP:0004430) | 3.97408258 |
| 5 | T lymphocytopenia (HP:0005403) | 3.88241926 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.81752520 |
| 7 | IgG deficiency (HP:0004315) | 3.76368660 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.71579166 |
| 9 | Increased CSF lactate (HP:0002490) | 3.70787171 |
| 10 | Abnormality of T cell number (HP:0011839) | 3.54146887 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.52977633 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.52971804 |
| 13 | Acute encephalopathy (HP:0006846) | 3.40554607 |
| 14 | Combined immunodeficiency (HP:0005387) | 3.39858923 |
| 15 | Prostate neoplasm (HP:0100787) | 3.37356304 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 3.36640079 |
| 17 | Hepatic necrosis (HP:0002605) | 3.19837406 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.15222349 |
| 19 | Abnormality of T cells (HP:0002843) | 3.12712235 |
| 20 | Abnormality of the prostate (HP:0008775) | 3.09457401 |
| 21 | Increased intramyocellular lipid droplets (HP:0012240) | 3.01092290 |
| 22 | Lipid accumulation in hepatocytes (HP:0006561) | 3.00938040 |
| 23 | Testicular atrophy (HP:0000029) | 2.98086452 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.89674629 |
| 25 | Hypoplasia of the uterus (HP:0000013) | 2.82513737 |
| 26 | Pancreatic cysts (HP:0001737) | 2.73605199 |
| 27 | Attenuation of retinal blood vessels (HP:0007843) | 2.67885228 |
| 28 | Thyroiditis (HP:0100646) | 2.65340617 |
| 29 | Increased serum lactate (HP:0002151) | 2.64113988 |
| 30 | Abnormality of B cell number (HP:0010975) | 2.63883487 |
| 31 | Hypoplasia of the pons (HP:0012110) | 2.63818852 |
| 32 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.59771223 |
| 33 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.51334441 |
| 34 | Abnormality of the pons (HP:0007361) | 2.46883828 |
| 35 | Concave nail (HP:0001598) | 2.45788376 |
| 36 | Pendular nystagmus (HP:0012043) | 2.44660688 |
| 37 | Cerebral edema (HP:0002181) | 2.44483226 |
| 38 | B lymphocytopenia (HP:0010976) | 2.43485071 |
| 39 | Type II lissencephaly (HP:0007260) | 2.42080445 |
| 40 | Autoimmune thrombocytopenia (HP:0001973) | 2.41431631 |
| 41 | Panhypogammaglobulinemia (HP:0003139) | 2.41101672 |
| 42 | Increased muscle lipid content (HP:0009058) | 2.38326178 |
| 43 | Abolished electroretinogram (ERG) (HP:0000550) | 2.35503275 |
| 44 | Pancreatic fibrosis (HP:0100732) | 2.34789909 |
| 45 | Absent thumb (HP:0009777) | 2.34283783 |
| 46 | Hypoproteinemia (HP:0003075) | 2.30439116 |
| 47 | Autoimmune hemolytic anemia (HP:0001890) | 2.30436227 |
| 48 | Lactic acidosis (HP:0003128) | 2.27780623 |
| 49 | Increased corneal curvature (HP:0100692) | 2.27466515 |
| 50 | Keratoconus (HP:0000563) | 2.27466515 |
| 51 | Oral leukoplakia (HP:0002745) | 2.27154916 |
| 52 | Abnormality of T cell physiology (HP:0011840) | 2.20738092 |
| 53 | Optic disc pallor (HP:0000543) | 2.20194258 |
| 54 | Pancytopenia (HP:0001876) | 2.19747269 |
| 55 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16674552 |
| 56 | 3-Methylglutaconic aciduria (HP:0003535) | 2.13654180 |
| 57 | Exertional dyspnea (HP:0002875) | 2.12389492 |
| 58 | Gastrointestinal infarctions (HP:0005244) | 2.10745878 |
| 59 | Aplastic anemia (HP:0001915) | 2.10725328 |
| 60 | True hermaphroditism (HP:0010459) | 2.10396105 |
| 61 | Chronic diarrhea (HP:0002028) | 2.09037248 |
| 62 | Increased serum ferritin (HP:0003281) | 2.06290141 |
| 63 | Meckel diverticulum (HP:0002245) | 2.04772162 |
| 64 | Respiratory failure (HP:0002878) | 2.04649383 |
| 65 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.03987733 |
| 66 | Hypoalbuminemia (HP:0003073) | 2.03867181 |
| 67 | Abnormal albumin level (HP:0012116) | 2.03867181 |
| 68 | Rough bone trabeculation (HP:0100670) | 2.02404166 |
| 69 | Conical tooth (HP:0000698) | 2.00547626 |
| 70 | Abnormality of eosinophils (HP:0001879) | 1.97287906 |
| 71 | Respiratory difficulties (HP:0002880) | 1.97075349 |
| 72 | Squamous cell carcinoma (HP:0002860) | 1.96178279 |
| 73 | Abnormality of the renal cortex (HP:0011035) | 1.95771021 |
| 74 | Cutaneous melanoma (HP:0012056) | 1.95329477 |
| 75 | Stomatitis (HP:0010280) | 1.94882907 |
| 76 | Recurrent viral infections (HP:0004429) | 1.94771035 |
| 77 | Abnormality of the ileum (HP:0001549) | 1.92464031 |
| 78 | Decreased central vision (HP:0007663) | 1.91012077 |
| 79 | Clubbing of toes (HP:0100760) | 1.90531646 |
| 80 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.90029041 |
| 81 | Abnormality of the preputium (HP:0100587) | 1.89457619 |
| 82 | Exercise intolerance (HP:0003546) | 1.86284832 |
| 83 | Encephalitis (HP:0002383) | 1.83605316 |
| 84 | Abnormality of male internal genitalia (HP:0000022) | 1.81429631 |
| 85 | Anorexia (HP:0002039) | 1.81267098 |
| 86 | Abnormal drinking behavior (HP:0030082) | 1.81008132 |
| 87 | Polydipsia (HP:0001959) | 1.81008132 |
| 88 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.79262751 |
| 89 | Lymphoma (HP:0002665) | 1.79218830 |
| 90 | Type I transferrin isoform profile (HP:0003642) | 1.78237103 |
| 91 | Premature graying of hair (HP:0002216) | 1.75731570 |
| 92 | Small hand (HP:0200055) | 1.74940424 |
| 93 | Abnormality of urine glucose concentration (HP:0011016) | 1.74320725 |
| 94 | Glycosuria (HP:0003076) | 1.74320725 |
| 95 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.73753687 |
| 96 | Recurrent cutaneous fungal infections (HP:0011370) | 1.73753687 |
| 97 | Bile duct proliferation (HP:0001408) | 1.73622174 |
| 98 | Abnormal biliary tract physiology (HP:0012439) | 1.73622174 |
| 99 | IgM deficiency (HP:0002850) | 1.72971076 |
| 100 | Increased serum pyruvate (HP:0003542) | 1.69779630 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 6.45737111 |
| 2 | TLK1 | 5.78686919 |
| 3 | TESK2 | 4.91415283 |
| 4 | KDR | 3.19408807 |
| 5 | VRK1 | 3.04125169 |
| 6 | VRK2 | 2.92131563 |
| 7 | SCYL2 | 2.68857565 |
| 8 | ADRBK2 | 2.16669192 |
| 9 | EIF2AK3 | 2.13983454 |
| 10 | TAOK3 | 1.80404654 |
| 11 | TXK | 1.79556152 |
| 12 | MAPKAPK3 | 1.79226777 |
| 13 | TESK1 | 1.74418609 |
| 14 | ITK | 1.72686953 |
| 15 | TEC | 1.58752951 |
| 16 | MAP4K2 | 1.48748984 |
| 17 | GRK1 | 1.47525663 |
| 18 | FRK | 1.44259933 |
| 19 | SRPK1 | 1.39294222 |
| 20 | LIMK1 | 1.38864193 |
| 21 | RPS6KA4 | 1.35843910 |
| 22 | TIE1 | 1.33779959 |
| 23 | MAP3K9 | 1.20621259 |
| 24 | EIF2AK2 | 1.18680360 |
| 25 | BRSK2 | 1.18530972 |
| 26 | KIT | 1.17010402 |
| 27 | EIF2AK1 | 1.14348904 |
| 28 | CSF1R | 1.13402503 |
| 29 | RPS6KA5 | 1.13012468 |
| 30 | NEK1 | 1.11937470 |
| 31 | PLK4 | 1.07800811 |
| 32 | WNK4 | 1.07517615 |
| 33 | FES | 1.07372958 |
| 34 | NUAK1 | 1.06305012 |
| 35 | PIM2 | 1.03374048 |
| 36 | TNK2 | 0.94364898 |
| 37 | MST4 | 0.91454178 |
| 38 | CSNK1G3 | 0.89933887 |
| 39 | GRK6 | 0.88134034 |
| 40 | AURKA | 0.86489540 |
| 41 | STK16 | 0.85350152 |
| 42 | MAP4K1 | 0.83774682 |
| 43 | PLK1 | 0.81890767 |
| 44 | ERBB3 | 0.80871172 |
| 45 | CAMKK2 | 0.79396683 |
| 46 | DAPK1 | 0.78379906 |
| 47 | CSNK1G1 | 0.77273998 |
| 48 | TAF1 | 0.77004510 |
| 49 | IKBKB | 0.74585625 |
| 50 | TRIM28 | 0.73445320 |
| 51 | PIM1 | 0.73377054 |
| 52 | BRSK1 | 0.70676022 |
| 53 | PDK2 | 0.68701884 |
| 54 | TBK1 | 0.68573803 |
| 55 | CDC7 | 0.68012944 |
| 56 | SYK | 0.65132660 |
| 57 | GRK5 | 0.64530974 |
| 58 | CDK7 | 0.64378175 |
| 59 | BMPR1B | 0.63297006 |
| 60 | CSNK1A1L | 0.58835357 |
| 61 | PRKCQ | 0.58599619 |
| 62 | PLK3 | 0.57629955 |
| 63 | BTK | 0.56611872 |
| 64 | MAP2K7 | 0.54913908 |
| 65 | CHEK2 | 0.54866966 |
| 66 | TSSK6 | 0.53756381 |
| 67 | DAPK3 | 0.52956655 |
| 68 | BCKDK | 0.52132713 |
| 69 | NME2 | 0.50600451 |
| 70 | CSNK1G2 | 0.48228429 |
| 71 | AURKB | 0.47772635 |
| 72 | LCK | 0.47573686 |
| 73 | LYN | 0.47134262 |
| 74 | ATR | 0.46531852 |
| 75 | SIK1 | 0.45918329 |
| 76 | FLT3 | 0.45558950 |
| 77 | INSRR | 0.45026938 |
| 78 | ADRBK1 | 0.43837118 |
| 79 | GRK7 | 0.43010690 |
| 80 | IKBKE | 0.39669197 |
| 81 | CHUK | 0.38389841 |
| 82 | PKN1 | 0.38067254 |
| 83 | PIK3CA | 0.33265820 |
| 84 | MAPKAPK5 | 0.32312102 |
| 85 | JAK3 | 0.32061831 |
| 86 | WEE1 | 0.30739491 |
| 87 | CSNK1D | 0.30728814 |
| 88 | CSNK2A1 | 0.30448046 |
| 89 | MAPK11 | 0.29677387 |
| 90 | BUB1 | 0.29388592 |
| 91 | OXSR1 | 0.28646755 |
| 92 | MAP3K14 | 0.28620650 |
| 93 | ZAP70 | 0.27467422 |
| 94 | CSNK1A1 | 0.27221257 |
| 95 | ROCK1 | 0.27152933 |
| 96 | PASK | 0.26061909 |
| 97 | AKT2 | 0.24002450 |
| 98 | NME1 | 0.23775154 |
| 99 | ABL2 | 0.23325825 |
| 100 | IGF1R | 0.21969320 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.13893337 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.79265472 |
| 3 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 3.28272219 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.64086193 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.61098909 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.56480111 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.50320458 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.47819400 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.37065104 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.34622033 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 2.31620257 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.24332726 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.23910211 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.20617481 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.08851496 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.05241221 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.95302406 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.94397889 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.93544909 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.77402500 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.71996925 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71344238 |
| 23 | Alcoholism_Homo sapiens_hsa05034 | 1.67302396 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.60454265 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.53591030 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.49747958 |
| 27 | Sulfur relay system_Homo sapiens_hsa04122 | 1.47500495 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.42437469 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.37893037 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.36026238 |
| 31 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.33211776 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.28383260 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.23633302 |
| 34 | Base excision repair_Homo sapiens_hsa03410 | 1.20009150 |
| 35 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19327279 |
| 36 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.05439512 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.02540795 |
| 38 | Protein export_Homo sapiens_hsa03060 | 1.00555621 |
| 39 | Basal transcription factors_Homo sapiens_hsa03022 | 0.98757218 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.96967408 |
| 41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94551144 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.92264217 |
| 43 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92180752 |
| 44 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.92162175 |
| 45 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.91903629 |
| 46 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.91692031 |
| 47 | Viral myocarditis_Homo sapiens_hsa05416 | 0.91612302 |
| 48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90622199 |
| 49 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.85731825 |
| 50 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.82860806 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.81625346 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.78926557 |
| 53 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.78868434 |
| 54 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78395781 |
| 55 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.74507547 |
| 56 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73370275 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71764982 |
| 58 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.70931310 |
| 59 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69939596 |
| 60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.68066006 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.67960103 |
| 62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.66217747 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.64836731 |
| 64 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.59511324 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.59379917 |
| 66 | Measles_Homo sapiens_hsa05162 | 0.57817651 |
| 67 | Apoptosis_Homo sapiens_hsa04210 | 0.55847720 |
| 68 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.55711940 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.50859814 |
| 70 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49067887 |
| 71 | Peroxisome_Homo sapiens_hsa04146 | 0.48353222 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.47090648 |
| 73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46808564 |
| 74 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.46247533 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44904264 |
| 76 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44017779 |
| 77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.43631463 |
| 78 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.43600699 |
| 79 | Legionellosis_Homo sapiens_hsa05134 | 0.40957925 |
| 80 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.40050565 |
| 81 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.39144623 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37409168 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.35980877 |
| 84 | Leishmaniasis_Homo sapiens_hsa05140 | 0.33850725 |
| 85 | HTLV-I infection_Homo sapiens_hsa05166 | 0.33467975 |
| 86 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.32880205 |
| 87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.30586549 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.25533874 |
| 89 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.25446664 |
| 90 | Malaria_Homo sapiens_hsa05144 | 0.24099511 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.23073938 |
| 92 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.23013671 |
| 93 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.22883572 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22336051 |
| 95 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.20035706 |
| 96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.20003169 |
| 97 | Shigellosis_Homo sapiens_hsa05131 | 0.19365893 |
| 98 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.18599400 |
| 99 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.17271984 |
| 100 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.17100503 |

