

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | opsonization (GO:0008228) | 9.89002725 |
| 2 | regulation of interleukin-8 secretion (GO:2000482) | 9.29179529 |
| 3 | response to lead ion (GO:0010288) | 8.21017153 |
| 4 | limb bud formation (GO:0060174) | 7.76663048 |
| 5 | positive regulation of T cell differentiation in thymus (GO:0033089) | 7.44511451 |
| 6 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 7.14903596 |
| 7 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 7.01166532 |
| 8 | gonadal mesoderm development (GO:0007506) | 6.71316891 |
| 9 | somite development (GO:0061053) | 6.06451599 |
| 10 | embryonic foregut morphogenesis (GO:0048617) | 5.65381370 |
| 11 | positive regulation of meiosis (GO:0045836) | 5.60807826 |
| 12 | cell proliferation involved in metanephros development (GO:0072203) | 5.53332850 |
| 13 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 5.50318320 |
| 14 | regulation of meiosis I (GO:0060631) | 5.48249966 |
| 15 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 5.42433980 |
| 16 | artery development (GO:0060840) | 5.38841280 |
| 17 | negative regulation of lipid storage (GO:0010888) | 5.29341251 |
| 18 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 5.21119638 |
| 19 | positive regulation of meiotic cell cycle (GO:0051446) | 5.20115259 |
| 20 | negative regulation of axon guidance (GO:1902668) | 5.16132823 |
| 21 | positive regulation of glomerulus development (GO:0090193) | 5.02209480 |
| 22 | chondrocyte proliferation (GO:0035988) | 4.94983842 |
| 23 | lung lobe morphogenesis (GO:0060463) | 4.90554348 |
| 24 | regulation of cardiac muscle cell contraction (GO:0086004) | 4.56521158 |
| 25 | lymphoid progenitor cell differentiation (GO:0002320) | 4.51478295 |
| 26 | pantothenate metabolic process (GO:0015939) | 4.49381608 |
| 27 | lung epithelium development (GO:0060428) | 4.45855858 |
| 28 | prostate gland growth (GO:0060736) | 4.29510371 |
| 29 | negative regulation of leukocyte chemotaxis (GO:0002689) | 4.29289265 |
| 30 | male sex determination (GO:0030238) | 4.28432495 |
| 31 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.27850947 |
| 32 | proteasome assembly (GO:0043248) | 4.27826568 |
| 33 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 4.22560646 |
| 34 | regulation of transforming growth factor beta1 production (GO:0032908) | 4.20744045 |
| 35 | regulation of chronic inflammatory response (GO:0002676) | 4.15427424 |
| 36 | thalamus development (GO:0021794) | 4.10504783 |
| 37 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 4.02028386 |
| 38 | axon extension involved in axon guidance (GO:0048846) | 4.02028386 |
| 39 | cell proliferation involved in kidney development (GO:0072111) | 4.00318308 |
| 40 | renal system development (GO:0072001) | 3.94970976 |
| 41 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.92205613 |
| 42 | positive regulation of male gonad development (GO:2000020) | 3.89520437 |
| 43 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 3.81254387 |
| 44 | regulation of mesoderm development (GO:2000380) | 3.80097142 |
| 45 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 3.77429389 |
| 46 | regulation of T cell differentiation in thymus (GO:0033081) | 3.76133719 |
| 47 | T cell lineage commitment (GO:0002360) | 3.64374303 |
| 48 | transepithelial transport (GO:0070633) | 3.63807693 |
| 49 | lung-associated mesenchyme development (GO:0060484) | 3.63400957 |
| 50 | regulation of glomerulus development (GO:0090192) | 3.62438267 |
| 51 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 3.61389007 |
| 52 | dorsal/ventral neural tube patterning (GO:0021904) | 3.54775773 |
| 53 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.52617586 |
| 54 | regulation of smooth muscle cell differentiation (GO:0051150) | 3.49753995 |
| 55 | branch elongation of an epithelium (GO:0060602) | 3.44107974 |
| 56 | regulation of actin filament-based movement (GO:1903115) | 3.43200138 |
| 57 | regulation of axon guidance (GO:1902667) | 3.42851103 |
| 58 | regulation of male gonad development (GO:2000018) | 3.42657812 |
| 59 | hindbrain development (GO:0030902) | 3.40597646 |
| 60 | chronic inflammatory response (GO:0002544) | 3.34450913 |
| 61 | acute inflammatory response (GO:0002526) | 3.33832060 |
| 62 | positive regulation of calcium ion import (GO:0090280) | 3.33146843 |
| 63 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.28209021 |
| 64 | astrocyte differentiation (GO:0048708) | 3.21349057 |
| 65 | protein-cofactor linkage (GO:0018065) | 3.20582562 |
| 66 | branching involved in salivary gland morphogenesis (GO:0060445) | 3.19178019 |
| 67 | otic vesicle formation (GO:0030916) | 3.18394186 |
| 68 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.17336398 |
| 69 | DNA integration (GO:0015074) | 3.15529350 |
| 70 | mesenchymal cell proliferation (GO:0010463) | 3.14880696 |
| 71 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.14321066 |
| 72 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.11708327 |
| 73 | cullin deneddylation (GO:0010388) | 3.11445113 |
| 74 | reproductive system development (GO:0061458) | 3.07881927 |
| 75 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.03967559 |
| 76 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.99381494 |
| 77 | acute-phase response (GO:0006953) | 2.96801707 |
| 78 | protein K11-linked deubiquitination (GO:0035871) | 2.96552591 |
| 79 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.96068736 |
| 80 | embryonic digestive tract morphogenesis (GO:0048557) | 2.94840764 |
| 81 | regulation of cellular extravasation (GO:0002691) | 2.92905027 |
| 82 | myotube differentiation (GO:0014902) | 2.92818943 |
| 83 | regulation of activin receptor signaling pathway (GO:0032925) | 2.92443646 |
| 84 | protein deneddylation (GO:0000338) | 2.89834794 |
| 85 | negative regulation of kidney development (GO:0090185) | 2.88781904 |
| 86 | negative chemotaxis (GO:0050919) | 2.88237398 |
| 87 | endothelial cell morphogenesis (GO:0001886) | 2.87497497 |
| 88 | male genitalia development (GO:0030539) | 2.87322253 |
| 89 | positive regulation of transforming growth factor beta production (GO:0071636) | 2.86853219 |
| 90 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.84998730 |
| 91 | regulation of mononuclear cell migration (GO:0071675) | 2.84407781 |
| 92 | pancreas development (GO:0031016) | 2.82355592 |
| 93 | Sertoli cell development (GO:0060009) | 2.77724449 |
| 94 | ectoderm development (GO:0007398) | 2.74393077 |
| 95 | negative thymic T cell selection (GO:0045060) | 2.71229849 |
| 96 | spinal cord motor neuron differentiation (GO:0021522) | 2.64866771 |
| 97 | negative T cell selection (GO:0043383) | 2.63151149 |
| 98 | chaperone-mediated protein transport (GO:0072321) | 2.63045152 |
| 99 | thyroid gland development (GO:0030878) | 2.61739186 |
| 100 | organ formation (GO:0048645) | 2.58065537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.25536988 |
| 2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.97578301 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.86661768 |
| 4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.84542677 |
| 5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.77865904 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.75106508 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64933379 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.63835035 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.62174411 |
| 10 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.54481670 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.52189729 |
| 12 | EWS_26573619_Chip-Seq_HEK293_Human | 2.38841655 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.34158990 |
| 14 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.29931764 |
| 15 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.21043780 |
| 16 | P300_19829295_ChIP-Seq_ESCs_Human | 2.20186618 |
| 17 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.16789376 |
| 18 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.15851314 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.14646017 |
| 20 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.02182806 |
| 21 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.95253258 |
| 22 | FUS_26573619_Chip-Seq_HEK293_Human | 1.94597179 |
| 23 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.93936401 |
| 24 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.93014222 |
| 25 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.82006803 |
| 26 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.79744301 |
| 27 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.76087713 |
| 28 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.72864052 |
| 29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.69159067 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.67843443 |
| 31 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.67745274 |
| 32 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.67745274 |
| 33 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.67296510 |
| 34 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.62734343 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.61877433 |
| 36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.60017581 |
| 37 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.53385212 |
| 38 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.48359000 |
| 39 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.45550256 |
| 40 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.45550256 |
| 41 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.43657219 |
| 42 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.43624993 |
| 43 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.43233640 |
| 44 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.42904676 |
| 45 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42507519 |
| 46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.39131406 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.39130767 |
| 48 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.37103698 |
| 49 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.35848535 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.34863323 |
| 51 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.32204138 |
| 52 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.31924384 |
| 53 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.29794388 |
| 54 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.29494116 |
| 55 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.29268744 |
| 56 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29217158 |
| 57 | STAT3_23295773_ChIP-Seq_U87_Human | 1.25850417 |
| 58 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24882349 |
| 59 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.24251229 |
| 60 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.24165287 |
| 61 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23624839 |
| 62 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.23524690 |
| 63 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.22596671 |
| 64 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.21273352 |
| 65 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.20526579 |
| 66 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.18652731 |
| 67 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.18006248 |
| 68 | TP53_16413492_ChIP-PET_HCT116_Human | 1.17554112 |
| 69 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.17526734 |
| 70 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.16990263 |
| 71 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.16468582 |
| 72 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.16317081 |
| 73 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.15905909 |
| 74 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.14261336 |
| 75 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.14201417 |
| 76 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.13786273 |
| 77 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.11569627 |
| 78 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08705559 |
| 79 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.06383657 |
| 80 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.06025766 |
| 81 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04294719 |
| 82 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.04208173 |
| 83 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.03571564 |
| 84 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.03563065 |
| 85 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.02281276 |
| 86 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00841011 |
| 87 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00770228 |
| 88 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.99585947 |
| 89 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98306593 |
| 90 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.97918019 |
| 91 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.97460329 |
| 92 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.97382982 |
| 93 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.96726358 |
| 94 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.96198241 |
| 95 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.96055790 |
| 96 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.95887198 |
| 97 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95700438 |
| 98 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.95543117 |
| 99 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.95280233 |
| 100 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.95255973 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003283_abnormal_digestive_organ | 8.24368468 |
| 2 | MP0002102_abnormal_ear_morphology | 5.15837814 |
| 3 | MP0003195_calcinosis | 4.72160738 |
| 4 | MP0002234_abnormal_pharynx_morphology | 4.14475323 |
| 5 | MP0009053_abnormal_anal_canal | 3.34511060 |
| 6 | MP0002138_abnormal_hepatobiliary_system | 3.20290780 |
| 7 | MP0002163_abnormal_gland_morphology | 2.95080147 |
| 8 | MP0000383_abnormal_hair_follicle | 2.72529335 |
| 9 | MP0000462_abnormal_digestive_system | 2.55443819 |
| 10 | MP0001873_stomach_inflammation | 2.37696948 |
| 11 | MP0002277_abnormal_respiratory_mucosa | 2.32499473 |
| 12 | MP0002282_abnormal_trachea_morphology | 2.19820062 |
| 13 | MP0010678_abnormal_skin_adnexa | 1.98911322 |
| 14 | MP0006054_spinal_hemorrhage | 1.98802263 |
| 15 | MP0004043_abnormal_pH_regulation | 1.91783585 |
| 16 | MP0010386_abnormal_urinary_bladder | 1.89575708 |
| 17 | MP0003806_abnormal_nucleotide_metabolis | 1.89527696 |
| 18 | MP0008058_abnormal_DNA_repair | 1.87062223 |
| 19 | MP0005171_absent_coat_pigmentation | 1.84699149 |
| 20 | MP0006292_abnormal_olfactory_placode | 1.84202928 |
| 21 | MP0002876_abnormal_thyroid_physiology | 1.76655635 |
| 22 | MP0002751_abnormal_autonomic_nervous | 1.74430843 |
| 23 | MP0001293_anophthalmia | 1.63337859 |
| 24 | MP0010368_abnormal_lymphatic_system | 1.63315318 |
| 25 | MP0003880_abnormal_central_pattern | 1.63008911 |
| 26 | MP0000613_abnormal_salivary_gland | 1.62928761 |
| 27 | MP0005084_abnormal_gallbladder_morpholo | 1.55129519 |
| 28 | MP0003252_abnormal_bile_duct | 1.54040823 |
| 29 | MP0003938_abnormal_ear_development | 1.53047602 |
| 30 | MP0004147_increased_porphyrin_level | 1.49640901 |
| 31 | MP0002928_abnormal_bile_duct | 1.38421110 |
| 32 | MP0005360_urolithiasis | 1.36279332 |
| 33 | MP0002233_abnormal_nose_morphology | 1.33339911 |
| 34 | MP0003950_abnormal_plasma_membrane | 1.32901472 |
| 35 | MP0003300_gastrointestinal_ulcer | 1.31484915 |
| 36 | MP0003646_muscle_fatigue | 1.31328149 |
| 37 | MP0001501_abnormal_sleep_pattern | 1.30953943 |
| 38 | MP0010030_abnormal_orbit_morphology | 1.29232961 |
| 39 | MP0005379_endocrine/exocrine_gland_phen | 1.27735835 |
| 40 | MP0008057_abnormal_DNA_replication | 1.26235672 |
| 41 | MP0003890_abnormal_embryonic-extraembry | 1.17955539 |
| 42 | MP0005365_abnormal_bile_salt | 1.14850922 |
| 43 | MP0000467_abnormal_esophagus_morphology | 1.12118645 |
| 44 | MP0000685_abnormal_immune_system | 1.12098813 |
| 45 | MP0009764_decreased_sensitivity_to | 1.11691759 |
| 46 | MP0009250_abnormal_appendicular_skeleto | 1.07186368 |
| 47 | MP0003119_abnormal_digestive_system | 1.05727655 |
| 48 | MP0003943_abnormal_hepatobiliary_system | 1.05383850 |
| 49 | MP0003937_abnormal_limbs/digits/tail_de | 1.04256860 |
| 50 | MP0004142_abnormal_muscle_tone | 1.01158795 |
| 51 | MP0002210_abnormal_sex_determination | 0.90293523 |
| 52 | MP0005410_abnormal_fertilization | 0.89592183 |
| 53 | MP0005253_abnormal_eye_physiology | 0.89499684 |
| 54 | MP0002736_abnormal_nociception_after | 0.89236396 |
| 55 | MP0001145_abnormal_male_reproductive | 0.89069042 |
| 56 | MP0000427_abnormal_hair_cycle | 0.87073953 |
| 57 | MP0008872_abnormal_physiological_respon | 0.86259538 |
| 58 | MP0009278_abnormal_bone_marrow | 0.85084567 |
| 59 | MP0001929_abnormal_gametogenesis | 0.84279523 |
| 60 | MP0005381_digestive/alimentary_phenotyp | 0.83065749 |
| 61 | MP0005220_abnormal_exocrine_pancreas | 0.82773327 |
| 62 | MP0001270_distended_abdomen | 0.82084326 |
| 63 | MP0005551_abnormal_eye_electrophysiolog | 0.81520653 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 0.81432078 |
| 65 | MP0003186_abnormal_redox_activity | 0.80652834 |
| 66 | MP0005423_abnormal_somatic_nervous | 0.79543586 |
| 67 | MP0002089_abnormal_postnatal_growth/wei | 0.78233239 |
| 68 | MP0000653_abnormal_sex_gland | 0.77944859 |
| 69 | MP0000538_abnormal_urinary_bladder | 0.76005891 |
| 70 | MP0005332_abnormal_amino_acid | 0.74901504 |
| 71 | MP0005085_abnormal_gallbladder_physiolo | 0.74217640 |
| 72 | MP0001119_abnormal_female_reproductive | 0.69676308 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.69671625 |
| 74 | MP0002095_abnormal_skin_pigmentation | 0.69112909 |
| 75 | MP0005671_abnormal_response_to | 0.68161443 |
| 76 | MP0001984_abnormal_olfaction | 0.66937975 |
| 77 | MP0000428_abnormal_craniofacial_morphol | 0.66344838 |
| 78 | MP0000026_abnormal_inner_ear | 0.66171575 |
| 79 | MP0001944_abnormal_pancreas_morphology | 0.65836403 |
| 80 | MP0001663_abnormal_digestive_system | 0.65529098 |
| 81 | MP0005408_hypopigmentation | 0.63882527 |
| 82 | MP0004272_abnormal_basement_membrane | 0.63555737 |
| 83 | MP0002132_abnormal_respiratory_system | 0.63155146 |
| 84 | MP0001764_abnormal_homeostasis | 0.61586447 |
| 85 | MP0001486_abnormal_startle_reflex | 0.61566721 |
| 86 | MP0002098_abnormal_vibrissa_morphology | 0.61311559 |
| 87 | MP0000049_abnormal_middle_ear | 0.60037982 |
| 88 | MP0001324_abnormal_eye_pigmentation | 0.59550048 |
| 89 | MP0006036_abnormal_mitochondrial_physio | 0.59428818 |
| 90 | MP0002938_white_spotting | 0.59159438 |
| 91 | MP0009785_altered_susceptibility_to | 0.58057870 |
| 92 | MP0001286_abnormal_eye_development | 0.56060225 |
| 93 | MP0001986_abnormal_taste_sensitivity | 0.53947873 |
| 94 | MP0001879_abnormal_lymphatic_vessel | 0.53716770 |
| 95 | MP0002254_reproductive_system_inflammat | 0.53053653 |
| 96 | MP0005310_abnormal_salivary_gland | 0.52222936 |
| 97 | MP0005174_abnormal_tail_pigmentation | 0.50190536 |
| 98 | MP0003698_abnormal_male_reproductive | 0.47840491 |
| 99 | MP0001485_abnormal_pinna_reflex | 0.47510809 |
| 100 | MP0003755_abnormal_palate_morphology | 0.46104922 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bilateral microphthalmos (HP:0007633) | 4.63869936 |
| 2 | Dyschromatopsia (HP:0007641) | 4.13540890 |
| 3 | Abnormal number of incisors (HP:0011064) | 4.11078210 |
| 4 | True hermaphroditism (HP:0010459) | 3.66936184 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.63495734 |
| 6 | Pancreatic cysts (HP:0001737) | 3.62622694 |
| 7 | Anophthalmia (HP:0000528) | 3.54773487 |
| 8 | Maternal diabetes (HP:0009800) | 3.41477885 |
| 9 | Abnormality of chromosome segregation (HP:0002916) | 3.35257461 |
| 10 | Central scotoma (HP:0000603) | 3.32558494 |
| 11 | Cerebral edema (HP:0002181) | 3.32071571 |
| 12 | Acute encephalopathy (HP:0006846) | 3.32053979 |
| 13 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.17607032 |
| 14 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.17607032 |
| 15 | Abnormality of the anterior horn cell (HP:0006802) | 3.15216692 |
| 16 | Degeneration of anterior horn cells (HP:0002398) | 3.15216692 |
| 17 | Oligodactyly (hands) (HP:0001180) | 3.14427834 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.09523177 |
| 19 | Gonadotropin excess (HP:0000837) | 3.06354518 |
| 20 | Male pseudohermaphroditism (HP:0000037) | 3.02855980 |
| 21 | 11 pairs of ribs (HP:0000878) | 2.98751032 |
| 22 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.96577033 |
| 23 | Ileus (HP:0002595) | 2.89087262 |
| 24 | Narrow nasal bridge (HP:0000446) | 2.88257421 |
| 25 | Colon cancer (HP:0003003) | 2.87843459 |
| 26 | Tented upper lip vermilion (HP:0010804) | 2.84030030 |
| 27 | Abnormality of the renal cortex (HP:0011035) | 2.71069501 |
| 28 | Tubular atrophy (HP:0000092) | 2.66996682 |
| 29 | Duodenal stenosis (HP:0100867) | 2.64263825 |
| 30 | Small intestinal stenosis (HP:0012848) | 2.64263825 |
| 31 | Abnormality of the corticospinal tract (HP:0002492) | 2.64085046 |
| 32 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.61908303 |
| 33 | Single umbilical artery (HP:0001195) | 2.61908303 |
| 34 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.61908303 |
| 35 | Pancreatic fibrosis (HP:0100732) | 2.59732259 |
| 36 | Hyperglycinemia (HP:0002154) | 2.54560056 |
| 37 | Septo-optic dysplasia (HP:0100842) | 2.52812284 |
| 38 | Abnormality of the renal medulla (HP:0100957) | 2.52244246 |
| 39 | Abnormality of the duodenum (HP:0002246) | 2.47128179 |
| 40 | Triphalangeal thumb (HP:0001199) | 2.45524648 |
| 41 | Anosmia (HP:0000458) | 2.43635433 |
| 42 | Scotoma (HP:0000575) | 2.41168541 |
| 43 | Nephronophthisis (HP:0000090) | 2.38386740 |
| 44 | Porencephaly (HP:0002132) | 2.37697160 |
| 45 | Abnormality of midbrain morphology (HP:0002418) | 2.37384525 |
| 46 | Molar tooth sign on MRI (HP:0002419) | 2.37384525 |
| 47 | Tubulointerstitial abnormality (HP:0001969) | 2.37270132 |
| 48 | Tubulointerstitial nephritis (HP:0001970) | 2.36712279 |
| 49 | Rectal prolapse (HP:0002035) | 2.33428480 |
| 50 | Growth hormone deficiency (HP:0000824) | 2.31133338 |
| 51 | Horizontal nystagmus (HP:0000666) | 2.31113175 |
| 52 | Abnormal sex determination (HP:0012244) | 2.27709852 |
| 53 | Sex reversal (HP:0012245) | 2.27709852 |
| 54 | Spinal muscular atrophy (HP:0007269) | 2.20334815 |
| 55 | Postaxial foot polydactyly (HP:0001830) | 2.20267061 |
| 56 | Mitochondrial inheritance (HP:0001427) | 2.20206442 |
| 57 | Double outlet right ventricle (HP:0001719) | 2.19887813 |
| 58 | Congenital malformation of the right heart (HP:0011723) | 2.19887813 |
| 59 | Abolished electroretinogram (ERG) (HP:0000550) | 2.18851240 |
| 60 | Oligodactyly (HP:0012165) | 2.16876089 |
| 61 | Hyperglycinuria (HP:0003108) | 2.16410589 |
| 62 | Increased CSF lactate (HP:0002490) | 2.15466112 |
| 63 | Preaxial hand polydactyly (HP:0001177) | 2.12151786 |
| 64 | Hypoplasia of the uterus (HP:0000013) | 2.12106484 |
| 65 | Tubulointerstitial fibrosis (HP:0005576) | 2.11334814 |
| 66 | Abnormality of glycine metabolism (HP:0010895) | 2.10084798 |
| 67 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.10084798 |
| 68 | Preaxial foot polydactyly (HP:0001841) | 2.08029566 |
| 69 | Medial flaring of the eyebrow (HP:0010747) | 2.05022119 |
| 70 | Optic disc pallor (HP:0000543) | 2.04889970 |
| 71 | Gaze-evoked nystagmus (HP:0000640) | 2.01408147 |
| 72 | Abnormality of the fibula (HP:0002991) | 2.00624735 |
| 73 | Increased corneal curvature (HP:0100692) | 2.00516152 |
| 74 | Keratoconus (HP:0000563) | 2.00516152 |
| 75 | Exocrine pancreatic insufficiency (HP:0001738) | 1.98665806 |
| 76 | Congenital stationary night blindness (HP:0007642) | 1.96983755 |
| 77 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.95910640 |
| 78 | Vertebral hypoplasia (HP:0008417) | 1.95910640 |
| 79 | Pigmentary retinal degeneration (HP:0001146) | 1.95155605 |
| 80 | Methylmalonic acidemia (HP:0002912) | 1.93522427 |
| 81 | Hyperventilation (HP:0002883) | 1.92821424 |
| 82 | Vitreoretinal degeneration (HP:0000655) | 1.92719954 |
| 83 | Hypoplastic left heart (HP:0004383) | 1.92446704 |
| 84 | Abnormality of chromosome stability (HP:0003220) | 1.90647464 |
| 85 | Abnormality of the right ventricle (HP:0001707) | 1.86759841 |
| 86 | Methylmalonic aciduria (HP:0012120) | 1.85529627 |
| 87 | Chorioretinal atrophy (HP:0000533) | 1.84978678 |
| 88 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.84117363 |
| 89 | Choroideremia (HP:0001139) | 1.83434677 |
| 90 | Prenatal maternal abnormality (HP:0002686) | 1.82747773 |
| 91 | Hypothermia (HP:0002045) | 1.82361479 |
| 92 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.81937883 |
| 93 | Thyroiditis (HP:0100646) | 1.81191095 |
| 94 | Gonadal dysgenesis (HP:0000133) | 1.81175818 |
| 95 | Cystic liver disease (HP:0006706) | 1.80869168 |
| 96 | Hepatocellular necrosis (HP:0001404) | 1.80562944 |
| 97 | Abnormal biliary tract morphology (HP:0012440) | 1.80200745 |
| 98 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.79083938 |
| 99 | Respiratory failure (HP:0002878) | 1.77592913 |
| 100 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.76597112 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LMTK2 | 6.78685842 |
| 2 | STK39 | 3.83451903 |
| 3 | ACVR1B | 3.76589941 |
| 4 | TRIM28 | 3.68304331 |
| 5 | PNCK | 3.49930831 |
| 6 | CASK | 3.16521602 |
| 7 | PBK | 2.76845468 |
| 8 | TAF1 | 2.65652475 |
| 9 | INSRR | 2.55692127 |
| 10 | BMPR1B | 2.45166604 |
| 11 | FRK | 1.90986078 |
| 12 | MAPKAPK3 | 1.86528335 |
| 13 | OXSR1 | 1.85689258 |
| 14 | STK38L | 1.71309837 |
| 15 | VRK2 | 1.67265384 |
| 16 | ZAK | 1.64383510 |
| 17 | PIK3CA | 1.59739181 |
| 18 | BUB1 | 1.39170694 |
| 19 | TGFBR1 | 1.36855577 |
| 20 | PASK | 1.35088008 |
| 21 | PRKG2 | 1.28884204 |
| 22 | VRK1 | 1.25947310 |
| 23 | MAP3K4 | 1.25583290 |
| 24 | NME1 | 1.24527253 |
| 25 | MAP3K2 | 1.23550949 |
| 26 | EPHB2 | 1.22985911 |
| 27 | CSNK1G3 | 1.22373390 |
| 28 | WNK4 | 1.21780712 |
| 29 | BCKDK | 1.19219595 |
| 30 | TNIK | 1.18009856 |
| 31 | ARAF | 1.17119810 |
| 32 | CSNK1G2 | 1.14855736 |
| 33 | EPHA4 | 1.11222584 |
| 34 | GRK1 | 1.10116511 |
| 35 | TXK | 1.09788450 |
| 36 | CSNK1G1 | 1.02804685 |
| 37 | PLK3 | 1.01711203 |
| 38 | BCR | 0.95770781 |
| 39 | MAP3K13 | 0.94551637 |
| 40 | NEK9 | 0.94327198 |
| 41 | PTK2B | 0.90654672 |
| 42 | NUAK1 | 0.89832383 |
| 43 | SRPK1 | 0.88774492 |
| 44 | FLT3 | 0.88156757 |
| 45 | CSNK1A1L | 0.83291180 |
| 46 | BRSK2 | 0.81282961 |
| 47 | DAPK1 | 0.78028795 |
| 48 | TAOK3 | 0.73517747 |
| 49 | TSSK6 | 0.73022697 |
| 50 | ERBB3 | 0.72842673 |
| 51 | WNK3 | 0.70608303 |
| 52 | MKNK1 | 0.69787160 |
| 53 | CAMK1G | 0.68088610 |
| 54 | STK24 | 0.66719865 |
| 55 | PRKCQ | 0.66639595 |
| 56 | TTK | 0.63174973 |
| 57 | ROCK1 | 0.62461265 |
| 58 | FGFR1 | 0.58440009 |
| 59 | EIF2AK3 | 0.58312748 |
| 60 | MELK | 0.56505358 |
| 61 | CDK19 | 0.56465975 |
| 62 | STK3 | 0.55371288 |
| 63 | KSR1 | 0.54531087 |
| 64 | NTRK3 | 0.54043411 |
| 65 | NLK | 0.52776754 |
| 66 | FGFR2 | 0.52737213 |
| 67 | CCNB1 | 0.51449753 |
| 68 | CDK9 | 0.50742891 |
| 69 | MARK3 | 0.49601119 |
| 70 | TIE1 | 0.48382674 |
| 71 | MARK1 | 0.43354741 |
| 72 | MKNK2 | 0.42522536 |
| 73 | BRAF | 0.41798622 |
| 74 | FER | 0.41432521 |
| 75 | EIF2AK1 | 0.41190510 |
| 76 | MAP3K9 | 0.40007996 |
| 77 | NEK6 | 0.38640351 |
| 78 | PRKG1 | 0.38566778 |
| 79 | RAF1 | 0.38249822 |
| 80 | BRSK1 | 0.36893158 |
| 81 | ADRBK2 | 0.35957249 |
| 82 | IGF1R | 0.35523421 |
| 83 | PRKCE | 0.34343879 |
| 84 | PKN2 | 0.34232516 |
| 85 | GRK5 | 0.33059160 |
| 86 | PRKCG | 0.33024553 |
| 87 | ATR | 0.28998119 |
| 88 | CLK1 | 0.28655553 |
| 89 | PAK3 | 0.27695410 |
| 90 | KSR2 | 0.26742667 |
| 91 | CDK8 | 0.26270404 |
| 92 | ATM | 0.26138582 |
| 93 | PLK1 | 0.25842864 |
| 94 | TEC | 0.25734860 |
| 95 | CSNK2A1 | 0.24432513 |
| 96 | CHUK | 0.23208840 |
| 97 | CHEK2 | 0.22390548 |
| 98 | DYRK2 | 0.21284096 |
| 99 | ADRBK1 | 0.19679697 |
| 100 | TYRO3 | 0.19396856 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.33963991 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.21223433 |
| 3 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 3.14585303 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 2.85860048 |
| 5 | Basal transcription factors_Homo sapiens_hsa03022 | 2.51828320 |
| 6 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.41204032 |
| 7 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.28019557 |
| 8 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.20840812 |
| 9 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.00071053 |
| 10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.88765089 |
| 11 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.87525129 |
| 12 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.87114305 |
| 13 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.85060256 |
| 14 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.81567303 |
| 15 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.78419246 |
| 16 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.77161261 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.76542609 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.76071100 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.74396436 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.73314617 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.64111175 |
| 22 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.61888729 |
| 23 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.58905619 |
| 24 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.54691513 |
| 25 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.45424473 |
| 26 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.43836977 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.42293880 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.41682702 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.38791083 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34030669 |
| 31 | Homologous recombination_Homo sapiens_hsa03440 | 1.32660977 |
| 32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.30080052 |
| 33 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.27280862 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.26323333 |
| 35 | Ribosome_Homo sapiens_hsa03010 | 1.25075390 |
| 36 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.20653097 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.20437148 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.18198835 |
| 39 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.11351760 |
| 40 | Histidine metabolism_Homo sapiens_hsa00340 | 1.10696318 |
| 41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.08729441 |
| 42 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.08655142 |
| 43 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.08432730 |
| 44 | Phototransduction_Homo sapiens_hsa04744 | 1.01916136 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00001934 |
| 46 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.97406581 |
| 47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.95969972 |
| 48 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.95534048 |
| 49 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.94295931 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.93557241 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.92749178 |
| 52 | ABC transporters_Homo sapiens_hsa02010 | 0.92347386 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92337917 |
| 54 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.88141977 |
| 55 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.84091930 |
| 56 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.83924068 |
| 57 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.83704985 |
| 58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.80615321 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80603931 |
| 60 | DNA replication_Homo sapiens_hsa03030 | 0.78145231 |
| 61 | Alzheimers disease_Homo sapiens_hsa05010 | 0.77971632 |
| 62 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.77621939 |
| 63 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.75837619 |
| 64 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.74670822 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.73720727 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.73384863 |
| 67 | Asthma_Homo sapiens_hsa05310 | 0.73158765 |
| 68 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.72440655 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71999018 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.70426524 |
| 71 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68101271 |
| 72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67323294 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62020093 |
| 74 | Tight junction_Homo sapiens_hsa04530 | 0.61429665 |
| 75 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.59871181 |
| 76 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.59861460 |
| 77 | Malaria_Homo sapiens_hsa05144 | 0.59353705 |
| 78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.54912910 |
| 79 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.52548500 |
| 80 | Morphine addiction_Homo sapiens_hsa05032 | 0.52450668 |
| 81 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.46715638 |
| 82 | Purine metabolism_Homo sapiens_hsa00230 | 0.46446493 |
| 83 | Cocaine addiction_Homo sapiens_hsa05030 | 0.45568789 |
| 84 | Base excision repair_Homo sapiens_hsa03410 | 0.45126438 |
| 85 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45016112 |
| 86 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.43866821 |
| 87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.43184321 |
| 88 | Bile secretion_Homo sapiens_hsa04976 | 0.41806113 |
| 89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38446178 |
| 90 | Metabolic pathways_Homo sapiens_hsa01100 | 0.37003184 |
| 91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.36949264 |
| 92 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.36573183 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.35027355 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34598758 |
| 95 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.34266710 |
| 96 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.33600163 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30164399 |
| 98 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.28867031 |
| 99 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.28856574 |
| 100 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.28783081 |

