

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of 5.8S rRNA (GO:0000460) | 6.02775763 |
| 2 | histone H2A acetylation (GO:0043968) | 5.91226342 |
| 3 | behavioral response to nicotine (GO:0035095) | 5.66858401 |
| 4 | phosphate ion transport (GO:0006817) | 5.01380036 |
| 5 | ubiquinone biosynthetic process (GO:0006744) | 4.77740018 |
| 6 | quinone biosynthetic process (GO:1901663) | 4.65252302 |
| 7 | kidney morphogenesis (GO:0060993) | 4.55240385 |
| 8 | ubiquinone metabolic process (GO:0006743) | 4.50170767 |
| 9 | urate metabolic process (GO:0046415) | 4.36570348 |
| 10 | regulation of meiosis I (GO:0060631) | 4.35761361 |
| 11 | trivalent inorganic anion homeostasis (GO:0072506) | 4.34147587 |
| 12 | phosphate ion homeostasis (GO:0055062) | 4.34147587 |
| 13 | proteasome assembly (GO:0043248) | 4.26106715 |
| 14 | phosphate ion transmembrane transport (GO:0035435) | 4.06901381 |
| 15 | negative regulation of T-helper cell differentiation (GO:0045623) | 4.04050258 |
| 16 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 4.04050258 |
| 17 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.96114889 |
| 18 | response to mercury ion (GO:0046689) | 3.95312721 |
| 19 | regulation of hippo signaling (GO:0035330) | 3.91420854 |
| 20 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.73337178 |
| 21 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.64936184 |
| 22 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.64936184 |
| 23 | negative regulation of meiosis (GO:0045835) | 3.48767149 |
| 24 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.48439030 |
| 25 | termination of RNA polymerase III transcription (GO:0006386) | 3.48439030 |
| 26 | pseudouridine synthesis (GO:0001522) | 3.47795348 |
| 27 | negative regulation of telomere maintenance (GO:0032205) | 3.45739621 |
| 28 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.39928275 |
| 29 | respiratory chain complex IV assembly (GO:0008535) | 3.36491165 |
| 30 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.32775372 |
| 31 | DNA deamination (GO:0045006) | 3.32463449 |
| 32 | growth hormone receptor signaling pathway (GO:0060396) | 3.32335791 |
| 33 | negative regulation of meiotic cell cycle (GO:0051447) | 3.30197743 |
| 34 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.23773299 |
| 35 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.20364940 |
| 36 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.20364940 |
| 37 | indole-containing compound metabolic process (GO:0042430) | 3.19994241 |
| 38 | energy homeostasis (GO:0097009) | 3.17732127 |
| 39 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.14489602 |
| 40 | tryptophan catabolic process (GO:0006569) | 3.14391825 |
| 41 | indole-containing compound catabolic process (GO:0042436) | 3.14391825 |
| 42 | indolalkylamine catabolic process (GO:0046218) | 3.14391825 |
| 43 | tachykinin receptor signaling pathway (GO:0007217) | 3.14041841 |
| 44 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.11612195 |
| 45 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.11003275 |
| 46 | regulation of immunoglobulin secretion (GO:0051023) | 3.08123553 |
| 47 | response to growth hormone (GO:0060416) | 3.03751649 |
| 48 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.03434653 |
| 49 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.01941044 |
| 50 | isotype switching (GO:0045190) | 3.01941044 |
| 51 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.01941044 |
| 52 | production of molecular mediator of immune response (GO:0002440) | 3.00401433 |
| 53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.00292450 |
| 54 | cellular response to growth hormone stimulus (GO:0071378) | 2.97962116 |
| 55 | cytokine production involved in immune response (GO:0002367) | 2.97877872 |
| 56 | regulation of podosome assembly (GO:0071801) | 2.97809998 |
| 57 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.95115127 |
| 58 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.91292253 |
| 59 | NADH dehydrogenase complex assembly (GO:0010257) | 2.91292253 |
| 60 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.91292253 |
| 61 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.90297079 |
| 62 | ATP synthesis coupled proton transport (GO:0015986) | 2.90297079 |
| 63 | regulation of chronic inflammatory response (GO:0002676) | 2.89485251 |
| 64 | synapsis (GO:0007129) | 2.87594376 |
| 65 | sulfation (GO:0051923) | 2.87091157 |
| 66 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.83665588 |
| 67 | protein complex biogenesis (GO:0070271) | 2.82140165 |
| 68 | tryptophan metabolic process (GO:0006568) | 2.77302829 |
| 69 | histone mRNA metabolic process (GO:0008334) | 2.76533133 |
| 70 | negative regulation of heart rate (GO:0010459) | 2.76167849 |
| 71 | dopamine transport (GO:0015872) | 2.75827687 |
| 72 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.71701813 |
| 73 | magnesium ion transport (GO:0015693) | 2.70352892 |
| 74 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.69226967 |
| 75 | cytochrome complex assembly (GO:0017004) | 2.65570917 |
| 76 | signal peptide processing (GO:0006465) | 2.64089471 |
| 77 | regulation of dopamine metabolic process (GO:0042053) | 2.63098211 |
| 78 | regulation of catecholamine metabolic process (GO:0042069) | 2.63098211 |
| 79 | protein localization to cilium (GO:0061512) | 2.62749376 |
| 80 | transcription from RNA polymerase III promoter (GO:0006383) | 2.61801374 |
| 81 | aminoglycoside antibiotic metabolic process (GO:0030647) | 2.59680775 |
| 82 | glycerol metabolic process (GO:0006071) | 2.59336335 |
| 83 | glial cell proliferation (GO:0014009) | 2.58427744 |
| 84 | fucose catabolic process (GO:0019317) | 2.58393035 |
| 85 | L-fucose metabolic process (GO:0042354) | 2.58393035 |
| 86 | L-fucose catabolic process (GO:0042355) | 2.58393035 |
| 87 | isoprenoid biosynthetic process (GO:0008299) | 2.57252619 |
| 88 | indolalkylamine metabolic process (GO:0006586) | 2.54211887 |
| 89 | mannosylation (GO:0097502) | 2.53610033 |
| 90 | cytokine biosynthetic process (GO:0042089) | 2.53202235 |
| 91 | spliceosomal snRNP assembly (GO:0000387) | 2.52853023 |
| 92 | T-helper cell differentiation (GO:0042093) | 2.49379726 |
| 93 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.49379726 |
| 94 | branched-chain amino acid catabolic process (GO:0009083) | 2.48975438 |
| 95 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.48931398 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.48245717 |
| 97 | telomere maintenance via telomerase (GO:0007004) | 2.48062043 |
| 98 | methionine biosynthetic process (GO:0009086) | 2.47666744 |
| 99 | regulation of proton transport (GO:0010155) | 2.47188176 |
| 100 | cardiac right ventricle morphogenesis (GO:0003215) | 2.45031174 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GATA1_22025678_ChIP-Seq_K562_Human | 5.72444683 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.52334459 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.35262277 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.14746076 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.05962876 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.69135853 |
| 7 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.58961099 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.58527064 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.47508856 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.40895841 |
| 11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.35230300 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.21618565 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.17432796 |
| 14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.08420392 |
| 15 | EWS_26573619_Chip-Seq_HEK293_Human | 1.93355780 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.91778874 |
| 17 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.89108180 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.84155871 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.81706601 |
| 20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.78640393 |
| 21 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.77035457 |
| 22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.70263909 |
| 23 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.67168673 |
| 24 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.63963901 |
| 25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.63403822 |
| 26 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.62240929 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.62137453 |
| 28 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.60683500 |
| 29 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.58179060 |
| 30 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.51692020 |
| 31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.50378758 |
| 32 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.47025597 |
| 33 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45421723 |
| 34 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.43499069 |
| 35 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.42853241 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42194918 |
| 37 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.39393417 |
| 38 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.38910165 |
| 39 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.38597233 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.37927773 |
| 41 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.37239084 |
| 42 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36296314 |
| 43 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.35364681 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34326127 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.34171499 |
| 46 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.32689004 |
| 47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29250445 |
| 48 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29250445 |
| 49 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.28214344 |
| 50 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.28127285 |
| 51 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27812605 |
| 52 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.25049595 |
| 53 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.24259822 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.22833213 |
| 55 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.18477909 |
| 56 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.18281780 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16346851 |
| 58 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.16127260 |
| 59 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.15330138 |
| 60 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.13918451 |
| 61 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.12587884 |
| 62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.12514304 |
| 63 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.11700696 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.11065608 |
| 65 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10829929 |
| 66 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10195982 |
| 67 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09609240 |
| 68 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.08126464 |
| 69 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.07816751 |
| 70 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.07299835 |
| 71 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.07066372 |
| 72 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05585003 |
| 73 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.05443670 |
| 74 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.04964504 |
| 75 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04916716 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04916716 |
| 77 | STAT3_23295773_ChIP-Seq_U87_Human | 1.04167244 |
| 78 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.04108568 |
| 79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03187347 |
| 80 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.02857274 |
| 81 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02198770 |
| 82 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00810126 |
| 83 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.00566692 |
| 84 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.97819135 |
| 85 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.97659712 |
| 86 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.96873207 |
| 87 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.96142930 |
| 88 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.96125424 |
| 89 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.96123227 |
| 90 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.95277188 |
| 91 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95063611 |
| 92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94833082 |
| 93 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.93286833 |
| 94 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.92676944 |
| 95 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92372755 |
| 96 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.92313936 |
| 97 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91734688 |
| 98 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.89947420 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89780066 |
| 100 | GATA3_26560356_Chip-Seq_TH2_Human | 0.89625482 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005360_urolithiasis | 7.71597937 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 6.92468967 |
| 3 | MP0000538_abnormal_urinary_bladder | 2.75887685 |
| 4 | MP0001348_abnormal_lacrimal_gland | 2.58849608 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.49894018 |
| 6 | MP0003195_calcinosis | 2.33051785 |
| 7 | MP0003878_abnormal_ear_physiology | 2.19783813 |
| 8 | MP0005377_hearing/vestibular/ear_phenot | 2.19783813 |
| 9 | MP0008872_abnormal_physiological_respon | 2.12252525 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.08594412 |
| 11 | MP0003252_abnormal_bile_duct | 2.01911192 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 1.88936136 |
| 13 | MP0001968_abnormal_touch/_nociception | 1.88469858 |
| 14 | MP0008058_abnormal_DNA_repair | 1.88192150 |
| 15 | MP0005645_abnormal_hypothalamus_physiol | 1.83831722 |
| 16 | MP0004147_increased_porphyrin_level | 1.81176902 |
| 17 | MP0009333_abnormal_splenocyte_physiolog | 1.80284747 |
| 18 | MP0000372_irregular_coat_pigmentation | 1.78398720 |
| 19 | MP0001984_abnormal_olfaction | 1.76190294 |
| 20 | MP0008877_abnormal_DNA_methylation | 1.72373141 |
| 21 | MP0003693_abnormal_embryo_hatching | 1.68289091 |
| 22 | MP0005551_abnormal_eye_electrophysiolog | 1.61910172 |
| 23 | MP0004043_abnormal_pH_regulation | 1.56910641 |
| 24 | MP0005332_abnormal_amino_acid | 1.55045307 |
| 25 | MP0004215_abnormal_myocardial_fiber | 1.54839736 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.52433968 |
| 27 | MP0002733_abnormal_thermal_nociception | 1.46509988 |
| 28 | MP0010386_abnormal_urinary_bladder | 1.44712464 |
| 29 | MP0002160_abnormal_reproductive_system | 1.40298668 |
| 30 | MP0010329_abnormal_lipoprotein_level | 1.38529115 |
| 31 | MP0005310_abnormal_salivary_gland | 1.31548061 |
| 32 | MP0000569_abnormal_digit_pigmentation | 1.30489538 |
| 33 | MP0001756_abnormal_urination | 1.30266763 |
| 34 | MP0004019_abnormal_vitamin_homeostasis | 1.28770983 |
| 35 | MP0002234_abnormal_pharynx_morphology | 1.26718207 |
| 36 | MP0005319_abnormal_enzyme/_coenzyme | 1.24755831 |
| 37 | MP0004145_abnormal_muscle_electrophysio | 1.22370752 |
| 38 | MP0002638_abnormal_pupillary_reflex | 1.21416663 |
| 39 | MP0005389_reproductive_system_phenotype | 1.21110505 |
| 40 | MP0003646_muscle_fatigue | 1.20470406 |
| 41 | MP0001873_stomach_inflammation | 1.20075193 |
| 42 | MP0005084_abnormal_gallbladder_morpholo | 1.18674538 |
| 43 | MP0005253_abnormal_eye_physiology | 1.18641839 |
| 44 | MP0004133_heterotaxia | 1.16864304 |
| 45 | MP0010234_abnormal_vibrissa_follicle | 1.15051507 |
| 46 | MP0003718_maternal_effect | 1.13752031 |
| 47 | MP0005220_abnormal_exocrine_pancreas | 1.13537368 |
| 48 | MP0001970_abnormal_pain_threshold | 1.13218294 |
| 49 | MP0006292_abnormal_olfactory_placode | 1.13172187 |
| 50 | MP0002736_abnormal_nociception_after | 1.11640223 |
| 51 | MP0001765_abnormal_ion_homeostasis | 1.09938087 |
| 52 | MP0002734_abnormal_mechanical_nocicepti | 1.09808537 |
| 53 | MP0000427_abnormal_hair_cycle | 1.03385993 |
| 54 | MP0005636_abnormal_mineral_homeostasis | 1.01352637 |
| 55 | MP0010678_abnormal_skin_adnexa | 0.99229798 |
| 56 | MP0010094_abnormal_chromosome_stability | 0.99197191 |
| 57 | MP0009643_abnormal_urine_homeostasis | 0.98165023 |
| 58 | MP0009765_abnormal_xenobiotic_induced | 0.95295427 |
| 59 | MP0000613_abnormal_salivary_gland | 0.94989830 |
| 60 | MP0005085_abnormal_gallbladder_physiolo | 0.93671056 |
| 61 | MP0002735_abnormal_chemical_nociception | 0.93223559 |
| 62 | MP0004085_abnormal_heartbeat | 0.93215336 |
| 63 | MP0001486_abnormal_startle_reflex | 0.93124185 |
| 64 | MP0003137_abnormal_impulse_conducting | 0.89444589 |
| 65 | MP0000631_abnormal_neuroendocrine_gland | 0.89329817 |
| 66 | MP0005167_abnormal_blood-brain_barrier | 0.88404623 |
| 67 | MP0000383_abnormal_hair_follicle | 0.88285390 |
| 68 | MP0009745_abnormal_behavioral_response | 0.88039768 |
| 69 | MP0006054_spinal_hemorrhage | 0.86278681 |
| 70 | MP0006035_abnormal_mitochondrial_morpho | 0.84589798 |
| 71 | MP0001545_abnormal_hematopoietic_system | 0.84496897 |
| 72 | MP0005397_hematopoietic_system_phenotyp | 0.84496897 |
| 73 | MP0002928_abnormal_bile_duct | 0.84458644 |
| 74 | MP0003111_abnormal_nucleus_morphology | 0.84056192 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.82354887 |
| 76 | MP0001764_abnormal_homeostasis | 0.80442159 |
| 77 | MP0003787_abnormal_imprinting | 0.80328974 |
| 78 | MP0001293_anophthalmia | 0.79313266 |
| 79 | MP0003283_abnormal_digestive_organ | 0.79145390 |
| 80 | MP0004134_abnormal_chest_morphology | 0.78618843 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.78551730 |
| 82 | MP0005646_abnormal_pituitary_gland | 0.76327976 |
| 83 | MP0002272_abnormal_nervous_system | 0.75253947 |
| 84 | MP0003806_abnormal_nucleotide_metabolis | 0.72276488 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.72085265 |
| 86 | MP0005671_abnormal_response_to | 0.71509988 |
| 87 | MP0006082_CNS_inflammation | 0.71371286 |
| 88 | MP0003880_abnormal_central_pattern | 0.69502826 |
| 89 | MP0005075_abnormal_melanosome_morpholog | 0.69045899 |
| 90 | MP0004885_abnormal_endolymph | 0.68908440 |
| 91 | MP0001501_abnormal_sleep_pattern | 0.68449065 |
| 92 | MP0009046_muscle_twitch | 0.68421115 |
| 93 | MP0001835_abnormal_antigen_presentation | 0.66176534 |
| 94 | MP0001790_abnormal_immune_system | 0.65700059 |
| 95 | MP0005387_immune_system_phenotype | 0.65700059 |
| 96 | MP0002166_altered_tumor_susceptibility | 0.61403211 |
| 97 | MP0009672_abnormal_birth_weight | 0.59573295 |
| 98 | MP0006036_abnormal_mitochondrial_physio | 0.59421418 |
| 99 | MP0004510_myositis | 0.58968212 |
| 100 | MP0001177_atelectasis | 0.58373196 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized aminoaciduria (HP:0002909) | 6.35079010 |
| 2 | Pendular nystagmus (HP:0012043) | 4.95137989 |
| 3 | Congenital stationary night blindness (HP:0007642) | 4.80080673 |
| 4 | Congenital, generalized hypertrichosis (HP:0004540) | 4.61188737 |
| 5 | Proximal tubulopathy (HP:0000114) | 4.45267783 |
| 6 | Pancreatic fibrosis (HP:0100732) | 4.14551846 |
| 7 | Type I transferrin isoform profile (HP:0003642) | 4.07166878 |
| 8 | Pancreatic cysts (HP:0001737) | 3.94390649 |
| 9 | Oral leukoplakia (HP:0002745) | 3.78921104 |
| 10 | True hermaphroditism (HP:0010459) | 3.74496232 |
| 11 | Severe visual impairment (HP:0001141) | 3.73956554 |
| 12 | Reduced antithrombin III activity (HP:0001976) | 3.72242497 |
| 13 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.30493586 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.26026760 |
| 15 | Renal cortical cysts (HP:0000803) | 3.24044953 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.22854092 |
| 17 | Abolished electroretinogram (ERG) (HP:0000550) | 3.05394145 |
| 18 | Dry hair (HP:0011359) | 3.04768333 |
| 19 | Agnosia (HP:0010524) | 3.01535541 |
| 20 | Increased corneal curvature (HP:0100692) | 3.01106537 |
| 21 | Keratoconus (HP:0000563) | 3.01106537 |
| 22 | Severe muscular hypotonia (HP:0006829) | 2.99809565 |
| 23 | Hepatic necrosis (HP:0002605) | 2.97439196 |
| 24 | Abnormality of secondary sexual hair (HP:0009888) | 2.93412748 |
| 25 | Abnormality of the axillary hair (HP:0100134) | 2.93412748 |
| 26 | Hypoglycemic coma (HP:0001325) | 2.92802498 |
| 27 | Cystic liver disease (HP:0006706) | 2.91683494 |
| 28 | Abnormality of the pons (HP:0007361) | 2.89252728 |
| 29 | Abnormal biliary tract physiology (HP:0012439) | 2.83724554 |
| 30 | Bile duct proliferation (HP:0001408) | 2.83724554 |
| 31 | Large for gestational age (HP:0001520) | 2.82463761 |
| 32 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.73528485 |
| 33 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.73528485 |
| 34 | Abnormal protein glycosylation (HP:0012346) | 2.73528485 |
| 35 | Abnormal glycosylation (HP:0012345) | 2.73528485 |
| 36 | Type II lissencephaly (HP:0007260) | 2.68235820 |
| 37 | Abnormality of the renal cortex (HP:0011035) | 2.66756412 |
| 38 | Nephronophthisis (HP:0000090) | 2.62731348 |
| 39 | Tongue fasciculations (HP:0001308) | 2.59291132 |
| 40 | Glycosuria (HP:0003076) | 2.54025280 |
| 41 | Abnormality of urine glucose concentration (HP:0011016) | 2.54025280 |
| 42 | Fair hair (HP:0002286) | 2.41972183 |
| 43 | Decreased central vision (HP:0007663) | 2.38834901 |
| 44 | Furrowed tongue (HP:0000221) | 2.32120333 |
| 45 | Abnormality of the renal medulla (HP:0100957) | 2.28459988 |
| 46 | Colon cancer (HP:0003003) | 2.27881862 |
| 47 | Sclerocornea (HP:0000647) | 2.27072070 |
| 48 | Ependymoma (HP:0002888) | 2.25856962 |
| 49 | Ridged nail (HP:0001807) | 2.24491204 |
| 50 | Increased CSF lactate (HP:0002490) | 2.16675295 |
| 51 | Sparse eyelashes (HP:0000653) | 2.15811339 |
| 52 | Muscle fibrillation (HP:0010546) | 2.15411886 |
| 53 | Hypoproteinemia (HP:0003075) | 2.13886284 |
| 54 | Attenuation of retinal blood vessels (HP:0007843) | 2.13652509 |
| 55 | Male pseudohermaphroditism (HP:0000037) | 2.11910788 |
| 56 | Homocystinuria (HP:0002156) | 2.11881567 |
| 57 | Abnormality of homocysteine metabolism (HP:0010919) | 2.11881567 |
| 58 | Hepatocellular necrosis (HP:0001404) | 2.11217962 |
| 59 | Parakeratosis (HP:0001036) | 2.10060007 |
| 60 | Mitochondrial inheritance (HP:0001427) | 2.08208249 |
| 61 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.03346211 |
| 62 | Congenital hepatic fibrosis (HP:0002612) | 2.02540254 |
| 63 | Neonatal respiratory distress (HP:0002643) | 2.02182766 |
| 64 | Acute necrotizing encephalopathy (HP:0006965) | 2.00450004 |
| 65 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.99656162 |
| 66 | Chorioretinal atrophy (HP:0000533) | 1.97599632 |
| 67 | Pachygyria (HP:0001302) | 1.95730789 |
| 68 | Hemiparesis (HP:0001269) | 1.95681463 |
| 69 | Abnormality of the renal collecting system (HP:0004742) | 1.95564754 |
| 70 | Nausea (HP:0002018) | 1.95420212 |
| 71 | Generalized hypopigmentation of hair (HP:0011358) | 1.94682823 |
| 72 | Hydroxyprolinuria (HP:0003080) | 1.94626371 |
| 73 | Abnormality of proline metabolism (HP:0010907) | 1.94626371 |
| 74 | Increased serum lactate (HP:0002151) | 1.94051325 |
| 75 | Prostate neoplasm (HP:0100787) | 1.91106029 |
| 76 | Aplastic anemia (HP:0001915) | 1.90287821 |
| 77 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.89853619 |
| 78 | Dicarboxylic aciduria (HP:0003215) | 1.89853619 |
| 79 | Abnormal pupillary function (HP:0007686) | 1.89709805 |
| 80 | Optic nerve hypoplasia (HP:0000609) | 1.89459463 |
| 81 | Congenital sensorineural hearing impairment (HP:0008527) | 1.88023937 |
| 82 | Type 2 muscle fiber atrophy (HP:0003554) | 1.84780364 |
| 83 | Hypoplasia of the pons (HP:0012110) | 1.84034546 |
| 84 | Progressive macrocephaly (HP:0004481) | 1.83681457 |
| 85 | Anencephaly (HP:0002323) | 1.83607609 |
| 86 | Progressive muscle weakness (HP:0003323) | 1.82905711 |
| 87 | Abnormality of vitamin B metabolism (HP:0004340) | 1.82667869 |
| 88 | Abnormality of placental membranes (HP:0011409) | 1.82126769 |
| 89 | Amniotic constriction ring (HP:0009775) | 1.82126769 |
| 90 | Lethargy (HP:0001254) | 1.82085011 |
| 91 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.82045563 |
| 92 | Decreased circulating renin level (HP:0003351) | 1.80825930 |
| 93 | Abnormality of methionine metabolism (HP:0010901) | 1.80403996 |
| 94 | Lactic acidosis (HP:0003128) | 1.80395874 |
| 95 | Hyperphosphaturia (HP:0003109) | 1.75365191 |
| 96 | Polydipsia (HP:0001959) | 1.74391938 |
| 97 | Abnormal drinking behavior (HP:0030082) | 1.74391938 |
| 98 | IgG deficiency (HP:0004315) | 1.74246653 |
| 99 | Stomach cancer (HP:0012126) | 1.72480744 |
| 100 | Abnormality of midbrain morphology (HP:0002418) | 1.71159006 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MKNK2 | 4.17747023 |
| 2 | BMPR1B | 4.13408055 |
| 3 | FRK | 3.54121879 |
| 4 | PBK | 3.03347536 |
| 5 | EIF2AK1 | 3.00409351 |
| 6 | TNIK | 2.99337669 |
| 7 | ADRBK2 | 2.96656727 |
| 8 | TRIM28 | 2.80051935 |
| 9 | TLK1 | 2.41994961 |
| 10 | MKNK1 | 2.38977849 |
| 11 | EPHA4 | 2.30340796 |
| 12 | SRPK1 | 2.27643634 |
| 13 | ZAK | 2.22222061 |
| 14 | TSSK6 | 1.98797688 |
| 15 | TGFBR1 | 1.96554660 |
| 16 | GRK1 | 1.92733809 |
| 17 | EIF2AK3 | 1.81050080 |
| 18 | BCKDK | 1.68863351 |
| 19 | OXSR1 | 1.67032000 |
| 20 | STK39 | 1.64286616 |
| 21 | MAP4K2 | 1.59614040 |
| 22 | MST4 | 1.58171380 |
| 23 | BUB1 | 1.49713419 |
| 24 | TXK | 1.48897297 |
| 25 | VRK1 | 1.46986389 |
| 26 | PLK3 | 1.46302186 |
| 27 | VRK2 | 1.44772361 |
| 28 | FLT3 | 1.43394843 |
| 29 | PKN2 | 1.42484108 |
| 30 | WNK4 | 1.42455461 |
| 31 | NME1 | 1.33893595 |
| 32 | WNK3 | 1.30468124 |
| 33 | TAOK3 | 1.25458107 |
| 34 | CDK19 | 1.24385024 |
| 35 | ACVR1B | 1.18639313 |
| 36 | PHKG2 | 1.12331668 |
| 37 | PHKG1 | 1.12331668 |
| 38 | INSRR | 1.01595357 |
| 39 | BRD4 | 0.99689567 |
| 40 | PINK1 | 0.95079043 |
| 41 | MARK3 | 0.93181617 |
| 42 | STK38L | 0.92788692 |
| 43 | CDK8 | 0.91831150 |
| 44 | FGFR2 | 0.78527830 |
| 45 | TIE1 | 0.77590695 |
| 46 | PRKCG | 0.77557612 |
| 47 | BCR | 0.75648417 |
| 48 | PLK4 | 0.73965333 |
| 49 | MAP2K6 | 0.72162040 |
| 50 | GRK5 | 0.71479772 |
| 51 | STK4 | 0.69662347 |
| 52 | DAPK2 | 0.67183602 |
| 53 | ALK | 0.66707448 |
| 54 | PRKD2 | 0.62829709 |
| 55 | NLK | 0.62420691 |
| 56 | STK3 | 0.62151483 |
| 57 | TTK | 0.61636765 |
| 58 | MAP3K14 | 0.61434832 |
| 59 | KIT | 0.60484828 |
| 60 | PIK3CA | 0.59305990 |
| 61 | ITK | 0.58192373 |
| 62 | MAP4K1 | 0.57748172 |
| 63 | GRK7 | 0.57565136 |
| 64 | PLK1 | 0.54404220 |
| 65 | PRKG2 | 0.53539813 |
| 66 | PTK2B | 0.48872293 |
| 67 | TNK2 | 0.48124748 |
| 68 | CSNK1G1 | 0.47466186 |
| 69 | CCNB1 | 0.46479785 |
| 70 | ADRBK1 | 0.46146665 |
| 71 | PLK2 | 0.46061735 |
| 72 | NEK1 | 0.44777769 |
| 73 | PNCK | 0.43735183 |
| 74 | IKBKB | 0.42454055 |
| 75 | EIF2AK2 | 0.41604542 |
| 76 | AURKA | 0.41032154 |
| 77 | CSNK1A1 | 0.40571976 |
| 78 | MAPK13 | 0.40322638 |
| 79 | CLK1 | 0.39675105 |
| 80 | ERBB3 | 0.39626055 |
| 81 | SYK | 0.37579206 |
| 82 | DYRK2 | 0.36623588 |
| 83 | RPS6KB1 | 0.36350901 |
| 84 | CSNK1G3 | 0.36132992 |
| 85 | NUAK1 | 0.35012774 |
| 86 | MAPKAPK3 | 0.34314150 |
| 87 | PRKCE | 0.34157890 |
| 88 | FGFR1 | 0.32225228 |
| 89 | IGF1R | 0.31716458 |
| 90 | KDR | 0.31630749 |
| 91 | OBSCN | 0.30290606 |
| 92 | CDC7 | 0.29281250 |
| 93 | CDK14 | 0.29109154 |
| 94 | MAP3K4 | 0.28478445 |
| 95 | PRKCA | 0.27930284 |
| 96 | STK16 | 0.26562946 |
| 97 | PRKACA | 0.26233383 |
| 98 | ATM | 0.23374498 |
| 99 | LCK | 0.22379285 |
| 100 | CDK6 | 0.22028789 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.06642246 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.37313903 |
| 3 | Asthma_Homo sapiens_hsa05310 | 2.92078533 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.77498969 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.42968416 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.31874780 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.31171297 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.27676134 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.25669575 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.09251144 |
| 11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.07056642 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.00170438 |
| 13 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.99064437 |
| 14 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.90119820 |
| 15 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.71999127 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.62963136 |
| 17 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.60511437 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.56876862 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.56296771 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.53367562 |
| 21 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.52093115 |
| 22 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.50536849 |
| 23 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.49550343 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.47710487 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.47408049 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.47178559 |
| 27 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.43181548 |
| 28 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.41161207 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.38445122 |
| 30 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.35031490 |
| 31 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.30567530 |
| 32 | Taste transduction_Homo sapiens_hsa04742 | 1.27149088 |
| 33 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.22371948 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17077396 |
| 35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.15630729 |
| 36 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.15129847 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.14506327 |
| 38 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.14307706 |
| 39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13487598 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 1.12431378 |
| 41 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.11887171 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.11085484 |
| 43 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10260221 |
| 44 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.08891167 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.06823265 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 1.04712090 |
| 47 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.98050272 |
| 48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.96026974 |
| 49 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.92235703 |
| 50 | Spliceosome_Homo sapiens_hsa03040 | 0.91340752 |
| 51 | Alzheimers disease_Homo sapiens_hsa05010 | 0.89576517 |
| 52 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.87943342 |
| 53 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.86990473 |
| 54 | Ribosome_Homo sapiens_hsa03010 | 0.85585783 |
| 55 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84998526 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.79909796 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.78424193 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77635834 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77479577 |
| 60 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.77432779 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.77202532 |
| 62 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.77050970 |
| 63 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.76215452 |
| 64 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.74844116 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.74589617 |
| 66 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.74122584 |
| 67 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.73758417 |
| 68 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.71474799 |
| 69 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.69737660 |
| 70 | Huntingtons disease_Homo sapiens_hsa05016 | 0.68439035 |
| 71 | Histidine metabolism_Homo sapiens_hsa00340 | 0.66715893 |
| 72 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.65219293 |
| 73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.64767239 |
| 74 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.63493971 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61882474 |
| 76 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60952670 |
| 77 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.60553486 |
| 78 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.57953059 |
| 79 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.57916780 |
| 80 | Base excision repair_Homo sapiens_hsa03410 | 0.54612060 |
| 81 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.52546045 |
| 82 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.52123074 |
| 83 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51899611 |
| 84 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.51802289 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51234032 |
| 86 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.50438891 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49131902 |
| 88 | Basal transcription factors_Homo sapiens_hsa03022 | 0.49041412 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.48320947 |
| 90 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.48100701 |
| 91 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.47527340 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47155518 |
| 93 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.45725247 |
| 94 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43683040 |
| 95 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.41780199 |
| 96 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.40848715 |
| 97 | Salivary secretion_Homo sapiens_hsa04970 | 0.40431597 |
| 98 | DNA replication_Homo sapiens_hsa03030 | 0.40416323 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.39921642 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.35755759 |

