| 1 | Birth length less than 3rd percentile (HP:0003561) | 4.70438542 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.46879471 |
| 3 | Abnormal number of erythroid precursors (HP:0012131) | 4.44540420 |
| 4 | Reticulocytopenia (HP:0001896) | 4.13458711 |
| 5 | Oral leukoplakia (HP:0002745) | 3.93883546 |
| 6 | Breast hypoplasia (HP:0003187) | 3.84196176 |
| 7 | Degeneration of anterior horn cells (HP:0002398) | 3.73114483 |
| 8 | Abnormality of the anterior horn cell (HP:0006802) | 3.73114483 |
| 9 | Carpal bone hypoplasia (HP:0001498) | 3.55389136 |
| 10 | Aplastic anemia (HP:0001915) | 3.50269130 |
| 11 | Rough bone trabeculation (HP:0100670) | 3.45868526 |
| 12 | Selective tooth agenesis (HP:0001592) | 3.45208259 |
| 13 | Hyperacusis (HP:0010780) | 3.40005861 |
| 14 | Cerebral hypomyelination (HP:0006808) | 3.25789996 |
| 15 | Premature rupture of membranes (HP:0001788) | 3.24778882 |
| 16 | Microvesicular hepatic steatosis (HP:0001414) | 3.21652354 |
| 17 | Achilles tendon contracture (HP:0001771) | 3.11820182 |
| 18 | Microretrognathia (HP:0000308) | 3.05533839 |
| 19 | Colon cancer (HP:0003003) | 3.05307731 |
| 20 | Macrocytic anemia (HP:0001972) | 3.03267030 |
| 21 | Trismus (HP:0000211) | 3.02673107 |
| 22 | Multiple enchondromatosis (HP:0005701) | 2.95780402 |
| 23 | Thrombocytosis (HP:0001894) | 2.88319742 |
| 24 | Ragged-red muscle fibers (HP:0003200) | 2.87036195 |
| 25 | Patellar aplasia (HP:0006443) | 2.86800968 |
| 26 | Insomnia (HP:0100785) | 2.79648644 |
| 27 | Vertebral compression fractures (HP:0002953) | 2.78041961 |
| 28 | Pallor (HP:0000980) | 2.77786561 |
| 29 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.77618629 |
| 30 | Abnormality of the Achilles tendon (HP:0005109) | 2.67916016 |
| 31 | Ependymoma (HP:0002888) | 2.63708633 |
| 32 | Neoplasm of the pancreas (HP:0002894) | 2.62022558 |
| 33 | Cholecystitis (HP:0001082) | 2.58835326 |
| 34 | Abnormal gallbladder physiology (HP:0012438) | 2.58835326 |
| 35 | 11 pairs of ribs (HP:0000878) | 2.57209602 |
| 36 | Distal lower limb amyotrophy (HP:0008944) | 2.56454894 |
| 37 | Premature graying of hair (HP:0002216) | 2.51383938 |
| 38 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.49166587 |
| 39 | Agnosia (HP:0010524) | 2.46178456 |
| 40 | Progressive muscle weakness (HP:0003323) | 2.45138294 |
| 41 | Absent thumb (HP:0009777) | 2.43526488 |
| 42 | Abnormality of glycolysis (HP:0004366) | 2.43404936 |
| 43 | Premature ovarian failure (HP:0008209) | 2.42758873 |
| 44 | Long palpebral fissure (HP:0000637) | 2.40304031 |
| 45 | Abnormal trabecular bone morphology (HP:0100671) | 2.39912844 |
| 46 | Medulloblastoma (HP:0002885) | 2.38081411 |
| 47 | IgM deficiency (HP:0002850) | 2.35246684 |
| 48 | Meckel diverticulum (HP:0002245) | 2.34317919 |
| 49 | Secondary amenorrhea (HP:0000869) | 2.33552742 |
| 50 | Ulnar bowing (HP:0003031) | 2.31324751 |
| 51 | Bone marrow hypocellularity (HP:0005528) | 2.29002077 |
| 52 | Megaloblastic anemia (HP:0001889) | 2.27752705 |
| 53 | Abnormality of the preputium (HP:0100587) | 2.27591302 |
| 54 | Myelodysplasia (HP:0002863) | 2.27517555 |
| 55 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.26492739 |
| 56 | Poor head control (HP:0002421) | 2.24676274 |
| 57 | Cellular immunodeficiency (HP:0005374) | 2.23911525 |
| 58 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.23763336 |
| 59 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.23640775 |
| 60 | Testicular atrophy (HP:0000029) | 2.21969016 |
| 61 | Chromsome breakage (HP:0040012) | 2.21563027 |
| 62 | Abnormality of the ileum (HP:0001549) | 2.21450458 |
| 63 | Basal cell carcinoma (HP:0002671) | 2.21043927 |
| 64 | Protrusio acetabuli (HP:0003179) | 2.18905753 |
| 65 | Slender long bone (HP:0003100) | 2.18503252 |
| 66 | Abnormality of chromosome stability (HP:0003220) | 2.18203808 |
| 67 | Abnormality of the umbilical cord (HP:0010881) | 2.12600263 |
| 68 | Absent radius (HP:0003974) | 2.11299517 |
| 69 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.10310393 |
| 70 | Single umbilical artery (HP:0001195) | 2.10310393 |
| 71 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.10310393 |
| 72 | Pancytopenia (HP:0001876) | 2.09832699 |
| 73 | Spastic diplegia (HP:0001264) | 2.09148351 |
| 74 | Abnormality of the calcaneus (HP:0008364) | 2.08930672 |
| 75 | Increased connective tissue (HP:0009025) | 2.08731697 |
| 76 | Broad distal phalanx of finger (HP:0009836) | 2.08549494 |
| 77 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.08122075 |
| 78 | Elbow flexion contracture (HP:0002987) | 2.04423478 |
| 79 | Distal lower limb muscle weakness (HP:0009053) | 2.03568357 |
| 80 | Sparse eyelashes (HP:0000653) | 2.03510412 |
| 81 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.03020666 |
| 82 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.03020666 |
| 83 | Overriding aorta (HP:0002623) | 2.02390654 |
| 84 | Increased serum pyruvate (HP:0003542) | 2.02369496 |
| 85 | Petechiae (HP:0000967) | 2.02274512 |
| 86 | Personality changes (HP:0000751) | 2.01998294 |
| 87 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.00700527 |
| 88 | Type I transferrin isoform profile (HP:0003642) | 2.00340298 |
| 89 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.98938986 |
| 90 | Abnormality of reticulocytes (HP:0004312) | 1.98405719 |
| 91 | Orthostatic hypotension (HP:0001278) | 1.98401419 |
| 92 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.98153418 |
| 93 | Glossoptosis (HP:0000162) | 1.98126723 |
| 94 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.96344494 |
| 95 | Back pain (HP:0003418) | 1.95051623 |
| 96 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.94815661 |
| 97 | Amaurosis fugax (HP:0100576) | 1.94706489 |
| 98 | Lymphoma (HP:0002665) | 1.94643044 |
| 99 | Fasciculations (HP:0002380) | 1.93446929 |
| 100 | Fragile skin (HP:0001030) | 1.93056009 |
| 101 | CNS hypomyelination (HP:0003429) | 1.92372729 |
| 102 | Aplasia involving forearm bones (HP:0009822) | 1.92297669 |
| 103 | Absent forearm bone (HP:0003953) | 1.92297669 |
| 104 | Generalized amyotrophy (HP:0003700) | 1.92280206 |
| 105 | Entropion (HP:0000621) | 1.91329865 |
| 106 | Tracheoesophageal fistula (HP:0002575) | 1.90424138 |
| 107 | Small intestinal stenosis (HP:0012848) | 1.90319910 |
| 108 | Duodenal stenosis (HP:0100867) | 1.90319910 |
| 109 | Increased serum lactate (HP:0002151) | 1.90191579 |
| 110 | Horseshoe kidney (HP:0000085) | 1.90119572 |
| 111 | Squamous cell carcinoma (HP:0002860) | 1.89841163 |
| 112 | Short nail (HP:0001799) | 1.89165297 |
| 113 | Nonimmune hydrops fetalis (HP:0001790) | 1.88993346 |
| 114 | Atresia of the external auditory canal (HP:0000413) | 1.88613689 |
| 115 | Cleft eyelid (HP:0000625) | 1.88607072 |
| 116 | Hypertensive crisis (HP:0100735) | 1.86845013 |
| 117 | Progressive external ophthalmoplegia (HP:0000590) | 1.86779732 |
| 118 | Impulsivity (HP:0100710) | 1.86671875 |
| 119 | Unilateral renal agenesis (HP:0000122) | 1.85443000 |
| 120 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.85075866 |
| 121 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.82989462 |
| 122 | Proximal placement of thumb (HP:0009623) | 1.82914435 |
| 123 | Calcaneovalgus deformity (HP:0001848) | 1.81244644 |
| 124 | Difficulty climbing stairs (HP:0003551) | 1.79313666 |
| 125 | Renal duplication (HP:0000075) | 1.78996662 |
| 126 | Deviation of the thumb (HP:0009603) | 1.78872764 |
| 127 | Postnatal microcephaly (HP:0005484) | 1.78838283 |
| 128 | Muscle fiber atrophy (HP:0100295) | 1.78495414 |
| 129 | Rhabdomyosarcoma (HP:0002859) | 1.78389840 |
| 130 | Hypokinesia (HP:0002375) | 1.78143261 |
| 131 | Spinal rigidity (HP:0003306) | 1.76926817 |
| 132 | Elfin facies (HP:0004428) | 1.75302856 |
| 133 | Osteolytic defects of the hand bones (HP:0009699) | 1.74858248 |
| 134 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.74858248 |
| 135 | Patellar dislocation (HP:0002999) | 1.74584588 |
| 136 | Abnormality of oral frenula (HP:0000190) | 1.74223113 |
| 137 | Hypoplasia of the pons (HP:0012110) | 1.74218578 |
| 138 | Increased nuchal translucency (HP:0010880) | 1.73982549 |
| 139 | Abnormal number of incisors (HP:0011064) | 1.73837584 |
| 140 | Abnormality of the tricuspid valve (HP:0001702) | 1.73626593 |
| 141 | Onycholysis (HP:0001806) | 1.73567754 |
| 142 | Missing ribs (HP:0000921) | 1.73155957 |
| 143 | Lower limb amyotrophy (HP:0007210) | 1.72039827 |
| 144 | Shoulder girdle muscle weakness (HP:0003547) | 1.70322355 |
| 145 | Sloping forehead (HP:0000340) | 1.70240767 |
| 146 | High anterior hairline (HP:0009890) | 1.69296131 |
| 147 | Irregular epiphyses (HP:0010582) | 1.69027299 |
| 148 | Neoplasm of the colon (HP:0100273) | 1.68849312 |
| 149 | Abnormality of T cell physiology (HP:0011840) | 1.68718294 |
| 150 | Myopathic facies (HP:0002058) | 1.68436197 |
| 151 | Distal upper limb amyotrophy (HP:0007149) | 1.68075189 |
| 152 | Upper limb amyotrophy (HP:0009129) | 1.68075189 |
| 153 | Deformed tarsal bones (HP:0008119) | 1.67996952 |
| 154 | Adenoma sebaceum (HP:0009720) | 1.67779843 |
| 155 | Angiofibromas (HP:0010615) | 1.67779843 |
| 156 | Facial cleft (HP:0002006) | 1.67498829 |
| 157 | Upper limb muscle weakness (HP:0003484) | 1.67374999 |
| 158 | Ankle contracture (HP:0006466) | 1.67159257 |
| 159 | Disproportionate tall stature (HP:0001519) | 1.67044247 |
| 160 | Reticulocytosis (HP:0001923) | 1.64574283 |
| 161 | Nail dystrophy (HP:0008404) | 1.64355159 |
| 162 | Pelvic girdle muscle weakness (HP:0003749) | 1.64304299 |
| 163 | Premature skin wrinkling (HP:0100678) | 1.64302245 |
| 164 | Ankyloglossia (HP:0010296) | 1.63366806 |
| 165 | Abnormal neuron morphology (HP:0012757) | 1.62810160 |
| 166 | Abnormality of the motor neurons (HP:0002450) | 1.62810160 |
| 167 | Poikiloderma (HP:0001029) | 1.62720023 |
| 168 | Natal tooth (HP:0000695) | 1.61400492 |
| 169 | Insulin resistance (HP:0000855) | 1.58313824 |
| 170 | Breech presentation (HP:0001623) | 1.54507116 |
EIF5A 
