

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.69812133 |
| 2 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 4.76766417 |
| 3 | cytidine deamination (GO:0009972) | 4.70560380 |
| 4 | cytidine metabolic process (GO:0046087) | 4.70560380 |
| 5 | cytidine catabolic process (GO:0006216) | 4.70560380 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.57886060 |
| 7 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.55539579 |
| 8 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.49379392 |
| 9 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.49379392 |
| 10 | rRNA modification (GO:0000154) | 4.44492159 |
| 11 | rRNA methylation (GO:0031167) | 4.41847359 |
| 12 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.36061698 |
| 13 | ATP synthesis coupled proton transport (GO:0015986) | 4.36061698 |
| 14 | actin nucleation (GO:0045010) | 4.02288275 |
| 15 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.90128690 |
| 16 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.86245623 |
| 17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.86245623 |
| 18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.86245623 |
| 19 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.83947149 |
| 20 | regulation of respiratory burst (GO:0060263) | 3.81281801 |
| 21 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.77154588 |
| 22 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.67301140 |
| 23 | protein neddylation (GO:0045116) | 3.62370981 |
| 24 | protein complex biogenesis (GO:0070271) | 3.59756377 |
| 25 | respiratory electron transport chain (GO:0022904) | 3.56980694 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.53926160 |
| 27 | platelet dense granule organization (GO:0060155) | 3.52637651 |
| 28 | electron transport chain (GO:0022900) | 3.50906581 |
| 29 | proteasome assembly (GO:0043248) | 3.49240986 |
| 30 | protein-cofactor linkage (GO:0018065) | 3.43015774 |
| 31 | deoxyribose phosphate catabolic process (GO:0046386) | 3.42807836 |
| 32 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.42067129 |
| 33 | regulation of hypersensitivity (GO:0002883) | 3.37865399 |
| 34 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.35343641 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.35240599 |
| 36 | interferon-gamma production (GO:0032609) | 3.33791872 |
| 37 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.28796196 |
| 38 | deoxyribonucleotide catabolic process (GO:0009264) | 3.28476636 |
| 39 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.25886123 |
| 40 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.22749822 |
| 41 | negative T cell selection (GO:0043383) | 3.22077804 |
| 42 | ribonucleoprotein complex disassembly (GO:0032988) | 3.21216089 |
| 43 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.17948226 |
| 44 | adenosine metabolic process (GO:0046085) | 3.17644114 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.16692510 |
| 46 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.16204745 |
| 47 | purine nucleotide salvage (GO:0032261) | 3.13632895 |
| 48 | immunoglobulin mediated immune response (GO:0016064) | 3.13107239 |
| 49 | viral mRNA export from host cell nucleus (GO:0046784) | 3.07473756 |
| 50 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.07065762 |
| 51 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.07065762 |
| 52 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.07065762 |
| 53 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.05742966 |
| 54 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.05742966 |
| 55 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.04553075 |
| 56 | regulation of DNA endoreduplication (GO:0032875) | 3.02773486 |
| 57 | behavioral response to nicotine (GO:0035095) | 2.98905490 |
| 58 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.97146661 |
| 59 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.94470520 |
| 60 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.94470520 |
| 61 | negative regulation of B cell apoptotic process (GO:0002903) | 2.94435963 |
| 62 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.93303292 |
| 63 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.92312733 |
| 64 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.90686332 |
| 65 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.88748019 |
| 66 | negative regulation of T cell apoptotic process (GO:0070233) | 2.87176360 |
| 67 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.87155101 |
| 68 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.86414946 |
| 69 | positive regulation of interleukin-17 production (GO:0032740) | 2.84929302 |
| 70 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.84524280 |
| 71 | negative regulation by host of viral transcription (GO:0043922) | 2.82648798 |
| 72 | sequestering of actin monomers (GO:0042989) | 2.82168227 |
| 73 | regulation of T cell tolerance induction (GO:0002664) | 2.81641529 |
| 74 | mast cell activation (GO:0045576) | 2.78191061 |
| 75 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.78108226 |
| 76 | T cell migration (GO:0072678) | 2.76669584 |
| 77 | B cell mediated immunity (GO:0019724) | 2.76600062 |
| 78 | GPI anchor biosynthetic process (GO:0006506) | 2.75981908 |
| 79 | respiratory chain complex IV assembly (GO:0008535) | 2.74966921 |
| 80 | T cell costimulation (GO:0031295) | 2.73197145 |
| 81 | positive regulation of tolerance induction (GO:0002645) | 2.73087169 |
| 82 | iron-sulfur cluster assembly (GO:0016226) | 2.72375221 |
| 83 | metallo-sulfur cluster assembly (GO:0031163) | 2.72375221 |
| 84 | T cell receptor signaling pathway (GO:0050852) | 2.70609436 |
| 85 | regulation of interleukin-8 secretion (GO:2000482) | 2.70282261 |
| 86 | lymphocyte costimulation (GO:0031294) | 2.69973875 |
| 87 | positive T cell selection (GO:0043368) | 2.69906408 |
| 88 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.68690729 |
| 89 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.68096816 |
| 90 | negative regulation of ligase activity (GO:0051352) | 2.68096816 |
| 91 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 2.68032580 |
| 92 | positive thymic T cell selection (GO:0045059) | 2.64300587 |
| 93 | hydrogen ion transmembrane transport (GO:1902600) | 2.61757376 |
| 94 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.61371048 |
| 95 | ribosomal small subunit assembly (GO:0000028) | 2.60606948 |
| 96 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.60110027 |
| 97 | base-excision repair, AP site formation (GO:0006285) | 2.59606052 |
| 98 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.57052776 |
| 99 | mast cell degranulation (GO:0043303) | 2.56496526 |
| 100 | mast cell activation involved in immune response (GO:0002279) | 2.56496526 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.15472460 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.91943676 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.85565694 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66152513 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.54910526 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.94100813 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.89464439 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.75102701 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.73027694 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38932895 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.38549321 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.38050984 |
| 13 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.32137926 |
| 14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.31700937 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.28441187 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.25896194 |
| 17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.22250619 |
| 18 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.17553609 |
| 19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.17483786 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.14272143 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.11479719 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.02780013 |
| 23 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.87099661 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.83602348 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.82281575 |
| 26 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.80455244 |
| 27 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.78398941 |
| 28 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.74874725 |
| 29 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.72417382 |
| 30 | MYB_26560356_Chip-Seq_TH2_Human | 1.70704465 |
| 31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.68868796 |
| 32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67202528 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63113769 |
| 34 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61513243 |
| 35 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.52911500 |
| 36 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.52025464 |
| 37 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.51332395 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.46570629 |
| 39 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.46549999 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.45595344 |
| 41 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.44986353 |
| 42 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.44561756 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.39406927 |
| 44 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.36904786 |
| 45 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.34802372 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32629634 |
| 47 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.32242708 |
| 48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.31178622 |
| 49 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.29926212 |
| 50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.28144029 |
| 51 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.27973135 |
| 52 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.27405068 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27353032 |
| 54 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27353032 |
| 55 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25646157 |
| 56 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.25347247 |
| 57 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.24287570 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.23238808 |
| 59 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23081940 |
| 60 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.19666395 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.19229615 |
| 62 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.18984522 |
| 63 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.18134924 |
| 64 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.17086928 |
| 65 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.16100897 |
| 66 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.13978126 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12918682 |
| 68 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.10957390 |
| 69 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10768457 |
| 70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.09380217 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.08886215 |
| 72 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.08169077 |
| 73 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.07689767 |
| 74 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.07689767 |
| 75 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.05481756 |
| 76 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.05178340 |
| 77 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.05160631 |
| 78 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.04820249 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03803363 |
| 80 | P300_27268052_Chip-Seq_Bcells_Human | 1.02516719 |
| 81 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.00555359 |
| 82 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.00375710 |
| 83 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.99814778 |
| 84 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.98488045 |
| 85 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.98408840 |
| 86 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.98360536 |
| 87 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.96763586 |
| 88 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95948040 |
| 89 | MYB_26560356_Chip-Seq_TH1_Human | 0.94888610 |
| 90 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94657064 |
| 91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.94591846 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.91131412 |
| 93 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90908635 |
| 94 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.90477815 |
| 95 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.89295722 |
| 96 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.88922118 |
| 97 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.88452461 |
| 98 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.88219144 |
| 99 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87567838 |
| 100 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.86585234 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.22790530 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.81783692 |
| 3 | MP0009785_altered_susceptibility_to | 2.76652151 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 2.60117657 |
| 5 | MP0002166_altered_tumor_susceptibility | 2.53210218 |
| 6 | MP0001986_abnormal_taste_sensitivity | 2.43506296 |
| 7 | MP0006072_abnormal_retinal_apoptosis | 2.38650402 |
| 8 | MP0003866_abnormal_defecation | 2.29038547 |
| 9 | MP0002163_abnormal_gland_morphology | 2.25478259 |
| 10 | MP0000372_irregular_coat_pigmentation | 2.11615445 |
| 11 | MP0004147_increased_porphyrin_level | 2.09621195 |
| 12 | MP0006276_abnormal_autonomic_nervous | 2.09239357 |
| 13 | MP0003646_muscle_fatigue | 2.01589742 |
| 14 | MP0005000_abnormal_immune_tolerance | 1.96255719 |
| 15 | MP0001800_abnormal_humoral_immune | 1.96140167 |
| 16 | MP0005360_urolithiasis | 1.90400583 |
| 17 | MP0002006_tumorigenesis | 1.87591586 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 1.86378119 |
| 19 | MP0008872_abnormal_physiological_respon | 1.84593489 |
| 20 | MP0002723_abnormal_immune_serum | 1.80509637 |
| 21 | MP0001919_abnormal_reproductive_system | 1.78922860 |
| 22 | MP0005387_immune_system_phenotype | 1.78652697 |
| 23 | MP0001790_abnormal_immune_system | 1.78652697 |
| 24 | MP0003724_increased_susceptibility_to | 1.78554113 |
| 25 | MP0009697_abnormal_copulation | 1.70156821 |
| 26 | MP0003763_abnormal_thymus_physiology | 1.69930928 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.69779093 |
| 28 | MP0002420_abnormal_adaptive_immunity | 1.69379190 |
| 29 | MP0005025_abnormal_response_to | 1.68772002 |
| 30 | MP0001819_abnormal_immune_cell | 1.65934822 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.65146550 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.63741556 |
| 33 | MP0002452_abnormal_antigen_presenting | 1.60653094 |
| 34 | MP0005646_abnormal_pituitary_gland | 1.57314175 |
| 35 | MP0006036_abnormal_mitochondrial_physio | 1.56658555 |
| 36 | MP0005647_abnormal_sex_gland | 1.56402571 |
| 37 | MP0002102_abnormal_ear_morphology | 1.55549517 |
| 38 | MP0009764_decreased_sensitivity_to | 1.53750331 |
| 39 | MP0005645_abnormal_hypothalamus_physiol | 1.53364317 |
| 40 | MP0005389_reproductive_system_phenotype | 1.49739154 |
| 41 | MP0001905_abnormal_dopamine_level | 1.48389465 |
| 42 | MP0002837_dystrophic_cardiac_calcinosis | 1.45067385 |
| 43 | MP0001968_abnormal_touch/_nociception | 1.40890745 |
| 44 | MP0001661_extended_life_span | 1.40067276 |
| 45 | MP0006082_CNS_inflammation | 1.30986184 |
| 46 | MP0003252_abnormal_bile_duct | 1.30453744 |
| 47 | MP0005084_abnormal_gallbladder_morpholo | 1.30344238 |
| 48 | MP0002933_joint_inflammation | 1.27972668 |
| 49 | MP0005075_abnormal_melanosome_morpholog | 1.24979891 |
| 50 | MP0005253_abnormal_eye_physiology | 1.24840765 |
| 51 | MP0005410_abnormal_fertilization | 1.22892147 |
| 52 | MP0010155_abnormal_intestine_physiology | 1.22480343 |
| 53 | MP0000716_abnormal_immune_system | 1.22194914 |
| 54 | MP0002398_abnormal_bone_marrow | 1.21684992 |
| 55 | MP0010386_abnormal_urinary_bladder | 1.21025586 |
| 56 | MP0005379_endocrine/exocrine_gland_phen | 1.18835021 |
| 57 | MP0001873_stomach_inflammation | 1.17967516 |
| 58 | MP0005636_abnormal_mineral_homeostasis | 1.16331600 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.15047424 |
| 60 | MP0002419_abnormal_innate_immunity | 1.14887363 |
| 61 | MP0000685_abnormal_immune_system | 1.14348243 |
| 62 | MP0003787_abnormal_imprinting | 1.13864786 |
| 63 | MP0001845_abnormal_inflammatory_respons | 1.11859712 |
| 64 | MP0002735_abnormal_chemical_nociception | 1.09134883 |
| 65 | MP0003195_calcinosis | 1.08281012 |
| 66 | MP0003878_abnormal_ear_physiology | 1.08245475 |
| 67 | MP0005377_hearing/vestibular/ear_phenot | 1.08245475 |
| 68 | MP0003075_altered_response_to | 1.07731003 |
| 69 | MP0002009_preneoplasia | 1.05533588 |
| 70 | MP0008469_abnormal_protein_level | 1.04931412 |
| 71 | MP0002160_abnormal_reproductive_system | 1.04901941 |
| 72 | MP0009379_abnormal_foot_pigmentation | 1.02391455 |
| 73 | MP0001756_abnormal_urination | 1.00336425 |
| 74 | MP0000689_abnormal_spleen_morphology | 0.99652927 |
| 75 | MP0001764_abnormal_homeostasis | 0.99214587 |
| 76 | MP0003436_decreased_susceptibility_to | 0.98862688 |
| 77 | MP0002429_abnormal_blood_cell | 0.98815913 |
| 78 | MP0001765_abnormal_ion_homeostasis | 0.98506338 |
| 79 | MP0003186_abnormal_redox_activity | 0.97125066 |
| 80 | MP0001727_abnormal_embryo_implantation | 0.95313969 |
| 81 | MP0009763_increased_sensitivity_to | 0.94239075 |
| 82 | MP0005464_abnormal_platelet_physiology | 0.93604023 |
| 83 | MP0004142_abnormal_muscle_tone | 0.92451103 |
| 84 | MP0002736_abnormal_nociception_after | 0.92298813 |
| 85 | MP0002733_abnormal_thermal_nociception | 0.90085136 |
| 86 | MP0002722_abnormal_immune_system | 0.87623984 |
| 87 | MP0003880_abnormal_central_pattern | 0.87248373 |
| 88 | MP0008058_abnormal_DNA_repair | 0.83832172 |
| 89 | MP0005165_increased_susceptibility_to | 0.81985528 |
| 90 | MP0003315_abnormal_perineum_morphology | 0.81949892 |
| 91 | MP0003786_premature_aging | 0.81749821 |
| 92 | MP0001542_abnormal_bone_strength | 0.79315370 |
| 93 | MP0006035_abnormal_mitochondrial_morpho | 0.77892424 |
| 94 | MP0003718_maternal_effect | 0.77032202 |
| 95 | MP0009643_abnormal_urine_homeostasis | 0.75776684 |
| 96 | MP0005166_decreased_susceptibility_to | 0.73551443 |
| 97 | MP0000639_abnormal_adrenal_gland | 0.72501139 |
| 98 | MP0008995_early_reproductive_senescence | 0.72497504 |
| 99 | MP0005332_abnormal_amino_acid | 0.71831417 |
| 100 | MP0002019_abnormal_tumor_incidence | 0.71640176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.53164645 |
| 2 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.63358670 |
| 3 | Abnormality of alanine metabolism (HP:0010916) | 4.63358670 |
| 4 | Hyperalaninemia (HP:0003348) | 4.63358670 |
| 5 | Chronic sinusitis (HP:0011109) | 4.36730532 |
| 6 | Hepatocellular necrosis (HP:0001404) | 4.00660381 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.98308662 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.87765825 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.87245044 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.70659593 |
| 11 | Hepatic necrosis (HP:0002605) | 3.49512343 |
| 12 | Chronic otitis media (HP:0000389) | 3.39385977 |
| 13 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.33998305 |
| 14 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.33998305 |
| 15 | Increased CSF lactate (HP:0002490) | 3.28324442 |
| 16 | Increased intramyocellular lipid droplets (HP:0012240) | 3.17817511 |
| 17 | Acute encephalopathy (HP:0006846) | 3.06315108 |
| 18 | Increased muscle lipid content (HP:0009058) | 3.01703853 |
| 19 | Severe combined immunodeficiency (HP:0004430) | 3.01066346 |
| 20 | Hypoproteinemia (HP:0003075) | 2.96382986 |
| 21 | Congenital stationary night blindness (HP:0007642) | 2.90760575 |
| 22 | Progressive macrocephaly (HP:0004481) | 2.85889474 |
| 23 | Renal Fanconi syndrome (HP:0001994) | 2.84103573 |
| 24 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.76957349 |
| 25 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.76957349 |
| 26 | Agammaglobulinemia (HP:0004432) | 2.75406354 |
| 27 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.72167202 |
| 28 | Lipid accumulation in hepatocytes (HP:0006561) | 2.68184002 |
| 29 | 3-Methylglutaconic aciduria (HP:0003535) | 2.68045017 |
| 30 | Cerebral edema (HP:0002181) | 2.66217985 |
| 31 | Increased serum lactate (HP:0002151) | 2.60422857 |
| 32 | Lactic acidosis (HP:0003128) | 2.56759596 |
| 33 | Type I transferrin isoform profile (HP:0003642) | 2.53779568 |
| 34 | Polydipsia (HP:0001959) | 2.52371464 |
| 35 | Abnormal drinking behavior (HP:0030082) | 2.52371464 |
| 36 | Increased hepatocellular lipid droplets (HP:0006565) | 2.46112582 |
| 37 | Constricted visual fields (HP:0001133) | 2.44244432 |
| 38 | Renal cortical cysts (HP:0000803) | 2.42417109 |
| 39 | Decreased circulating renin level (HP:0003351) | 2.41077232 |
| 40 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.39851727 |
| 41 | Microretrognathia (HP:0000308) | 2.34797138 |
| 42 | IgG deficiency (HP:0004315) | 2.31916044 |
| 43 | Panhypogammaglobulinemia (HP:0003139) | 2.31681211 |
| 44 | Petechiae (HP:0000967) | 2.30906198 |
| 45 | T lymphocytopenia (HP:0005403) | 2.30309777 |
| 46 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.28738184 |
| 47 | Abolished electroretinogram (ERG) (HP:0000550) | 2.26468412 |
| 48 | Radial bowing (HP:0002986) | 2.24534487 |
| 49 | Leukodystrophy (HP:0002415) | 2.24265840 |
| 50 | Exertional dyspnea (HP:0002875) | 2.24177730 |
| 51 | Type 2 muscle fiber atrophy (HP:0003554) | 2.22309180 |
| 52 | Abnormality of serum amino acid levels (HP:0003112) | 2.19060785 |
| 53 | Cerebral palsy (HP:0100021) | 2.17270830 |
| 54 | Optic disc pallor (HP:0000543) | 2.16121432 |
| 55 | Respiratory failure (HP:0002878) | 2.15529235 |
| 56 | Abnormality of the prostate (HP:0008775) | 2.15178869 |
| 57 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.14647951 |
| 58 | Short tibia (HP:0005736) | 2.13068341 |
| 59 | Combined immunodeficiency (HP:0005387) | 2.12178390 |
| 60 | Abnormality of T cell number (HP:0011839) | 2.11807768 |
| 61 | Abnormality of midbrain morphology (HP:0002418) | 2.04873147 |
| 62 | Molar tooth sign on MRI (HP:0002419) | 2.04873147 |
| 63 | Abnormality of eosinophils (HP:0001879) | 2.03029884 |
| 64 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.01270341 |
| 65 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.00445497 |
| 66 | Generalized aminoaciduria (HP:0002909) | 2.00056440 |
| 67 | Dicarboxylic aciduria (HP:0003215) | 1.99201461 |
| 68 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.99201461 |
| 69 | Amyotrophic lateral sclerosis (HP:0007354) | 1.98198241 |
| 70 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.97848226 |
| 71 | Autoimmune hemolytic anemia (HP:0001890) | 1.97762520 |
| 72 | Muscle fiber atrophy (HP:0100295) | 1.97596091 |
| 73 | Thyroiditis (HP:0100646) | 1.95811432 |
| 74 | Adrenal hypoplasia (HP:0000835) | 1.94924672 |
| 75 | Recurrent cutaneous fungal infections (HP:0011370) | 1.93777227 |
| 76 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.93777227 |
| 77 | Polyuria (HP:0000103) | 1.93489512 |
| 78 | Exercise intolerance (HP:0003546) | 1.93477982 |
| 79 | Congenital, generalized hypertrichosis (HP:0004540) | 1.92075937 |
| 80 | Nephronophthisis (HP:0000090) | 1.90002198 |
| 81 | Reduced antithrombin III activity (HP:0001976) | 1.87701710 |
| 82 | Chronic diarrhea (HP:0002028) | 1.84055577 |
| 83 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.83849457 |
| 84 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.83849457 |
| 85 | Abnormal protein glycosylation (HP:0012346) | 1.83849457 |
| 86 | Abnormal glycosylation (HP:0012345) | 1.83849457 |
| 87 | Abnormal ciliary motility (HP:0012262) | 1.82542464 |
| 88 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.81989383 |
| 89 | Pancytopenia (HP:0001876) | 1.81217625 |
| 90 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.79646159 |
| 91 | Absent/shortened dynein arms (HP:0200106) | 1.79646159 |
| 92 | CNS demyelination (HP:0007305) | 1.79213772 |
| 93 | Porencephaly (HP:0002132) | 1.79018638 |
| 94 | Pancreatic cysts (HP:0001737) | 1.78181661 |
| 95 | Abnormality of renal resorption (HP:0011038) | 1.77628737 |
| 96 | Encephalitis (HP:0002383) | 1.77121711 |
| 97 | Submucous cleft hard palate (HP:0000176) | 1.76709229 |
| 98 | Supernumerary spleens (HP:0009799) | 1.75952768 |
| 99 | Clumsiness (HP:0002312) | 1.75504089 |
| 100 | Meningitis (HP:0001287) | 1.75264590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.97898674 |
| 2 | KDR | 4.62659272 |
| 3 | MAP4K2 | 3.64530006 |
| 4 | TLK1 | 3.14521482 |
| 5 | BCKDK | 2.94601757 |
| 6 | ZAK | 2.72523654 |
| 7 | MAP3K12 | 2.41588854 |
| 8 | BMPR2 | 2.27812475 |
| 9 | MAP3K11 | 2.13668511 |
| 10 | SCYL2 | 2.05443316 |
| 11 | MAP4K1 | 2.02923525 |
| 12 | BLK | 2.00427526 |
| 13 | TXK | 1.77025053 |
| 14 | MATK | 1.55645489 |
| 15 | INSRR | 1.50822686 |
| 16 | ADRBK2 | 1.45565847 |
| 17 | ITK | 1.45301491 |
| 18 | TAOK3 | 1.43956248 |
| 19 | TESK1 | 1.43112403 |
| 20 | TEC | 1.40933568 |
| 21 | MYLK | 1.36811319 |
| 22 | GRK1 | 1.36512967 |
| 23 | LIMK1 | 1.33605143 |
| 24 | DAPK1 | 1.32603284 |
| 25 | CSF1R | 1.30466372 |
| 26 | PINK1 | 1.29632432 |
| 27 | BTK | 1.29416718 |
| 28 | MST4 | 1.27124137 |
| 29 | STK16 | 1.24617213 |
| 30 | KIT | 1.23869090 |
| 31 | WNK4 | 1.20226521 |
| 32 | SYK | 1.19934176 |
| 33 | PIM2 | 1.13711372 |
| 34 | RPS6KA4 | 1.13366895 |
| 35 | IKBKB | 1.13181417 |
| 36 | PRKCQ | 1.12814146 |
| 37 | JAK3 | 1.12050218 |
| 38 | RPS6KA5 | 1.08539511 |
| 39 | PIK3CA | 1.06276891 |
| 40 | BUB1 | 1.05195556 |
| 41 | VRK1 | 0.97962209 |
| 42 | VRK2 | 0.94971148 |
| 43 | CCNB1 | 0.92388009 |
| 44 | NUAK1 | 0.91224217 |
| 45 | LCK | 0.84235383 |
| 46 | ARAF | 0.83815064 |
| 47 | DAPK3 | 0.83342361 |
| 48 | LYN | 0.82957547 |
| 49 | GRK7 | 0.81253090 |
| 50 | NME1 | 0.73795340 |
| 51 | ILK | 0.73078097 |
| 52 | PIK3CG | 0.67085740 |
| 53 | MUSK | 0.64857078 |
| 54 | OXSR1 | 0.63625504 |
| 55 | IGF1R | 0.63604411 |
| 56 | AURKA | 0.63094727 |
| 57 | LMTK2 | 0.61548955 |
| 58 | GRK6 | 0.61102330 |
| 59 | CASK | 0.60390717 |
| 60 | ADRBK1 | 0.59416136 |
| 61 | SRPK1 | 0.57561705 |
| 62 | TIE1 | 0.56761042 |
| 63 | FES | 0.56685881 |
| 64 | ERBB3 | 0.56596686 |
| 65 | PLK4 | 0.56401948 |
| 66 | FRK | 0.51992973 |
| 67 | OBSCN | 0.50295976 |
| 68 | ZAP70 | 0.49711648 |
| 69 | PRKCE | 0.48240408 |
| 70 | ROCK1 | 0.47930339 |
| 71 | MAP2K7 | 0.47614995 |
| 72 | ERBB2 | 0.47502502 |
| 73 | FLT3 | 0.47387694 |
| 74 | TBK1 | 0.46806428 |
| 75 | PIM1 | 0.46154943 |
| 76 | CSNK1G3 | 0.45208714 |
| 77 | PASK | 0.45099368 |
| 78 | TRPM7 | 0.43363471 |
| 79 | PAK1 | 0.42919307 |
| 80 | CAMK2G | 0.42036466 |
| 81 | PRKACA | 0.41343104 |
| 82 | ATR | 0.40381506 |
| 83 | CSK | 0.40330198 |
| 84 | DYRK2 | 0.40157792 |
| 85 | AURKB | 0.39994079 |
| 86 | CSNK2A1 | 0.39897494 |
| 87 | PRKCA | 0.38923883 |
| 88 | ABL2 | 0.38247546 |
| 89 | CDC7 | 0.37973226 |
| 90 | MAP3K5 | 0.37780182 |
| 91 | EGFR | 0.37679684 |
| 92 | EIF2AK3 | 0.36947605 |
| 93 | NTRK1 | 0.36626554 |
| 94 | CSNK1G2 | 0.35763078 |
| 95 | FGR | 0.35576228 |
| 96 | INSR | 0.35460040 |
| 97 | MAPKAPK3 | 0.35109326 |
| 98 | HCK | 0.32921749 |
| 99 | TNK2 | 0.31500233 |
| 100 | STK39 | 0.31305997 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.29649368 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.60533014 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.39038107 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34113269 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.12289571 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.11967153 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00605592 |
| 8 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.81028195 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.75446293 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.66510603 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.58234303 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.51111540 |
| 13 | Ribosome_Homo sapiens_hsa03010 | 2.22880876 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 2.04836303 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89281395 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.75645575 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.73964956 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.73603721 |
| 19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70323730 |
| 20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.68666698 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.62878776 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.58668326 |
| 23 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.54073148 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.44798493 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.44178832 |
| 26 | Viral myocarditis_Homo sapiens_hsa05416 | 1.43006943 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.24058744 |
| 28 | Leishmaniasis_Homo sapiens_hsa05140 | 1.20578229 |
| 29 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.13083209 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.10210953 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.06166113 |
| 32 | Sulfur relay system_Homo sapiens_hsa04122 | 1.02447361 |
| 33 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.02122922 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 1.01098326 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.96494713 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.95011441 |
| 37 | Homologous recombination_Homo sapiens_hsa03440 | 0.93403075 |
| 38 | Salmonella infection_Homo sapiens_hsa05132 | 0.92018247 |
| 39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.89762668 |
| 40 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.89747880 |
| 41 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.89387416 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.86829092 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.85898236 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.85505961 |
| 45 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.80421816 |
| 46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.79022103 |
| 47 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.77758110 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76853741 |
| 49 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75591950 |
| 50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.73023927 |
| 51 | Purine metabolism_Homo sapiens_hsa00230 | 0.72986923 |
| 52 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67836761 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.67748461 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.66930534 |
| 55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64439451 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64186032 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63811307 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62734576 |
| 59 | Mismatch repair_Homo sapiens_hsa03430 | 0.60970416 |
| 60 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.59508091 |
| 61 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59390992 |
| 62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57611575 |
| 63 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.55194644 |
| 64 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.54517541 |
| 65 | Base excision repair_Homo sapiens_hsa03410 | 0.54399726 |
| 66 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53878116 |
| 67 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.52505953 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52108567 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.47924103 |
| 70 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.45582939 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43969606 |
| 72 | Legionellosis_Homo sapiens_hsa05134 | 0.42839984 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41485998 |
| 74 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41347759 |
| 75 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41340459 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.40294067 |
| 77 | Shigellosis_Homo sapiens_hsa05131 | 0.39295180 |
| 78 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.36206314 |
| 79 | Tuberculosis_Homo sapiens_hsa05152 | 0.36045282 |
| 80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.35369860 |
| 81 | Phagosome_Homo sapiens_hsa04145 | 0.35223297 |
| 82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.33904955 |
| 83 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.32414200 |
| 84 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.31329254 |
| 85 | Pertussis_Homo sapiens_hsa05133 | 0.29944286 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.29421779 |
| 87 | RNA transport_Homo sapiens_hsa03013 | 0.28998110 |
| 88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28809982 |
| 89 | Taste transduction_Homo sapiens_hsa04742 | 0.28763992 |
| 90 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.28578370 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.26898633 |
| 92 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25651106 |
| 93 | Basal transcription factors_Homo sapiens_hsa03022 | 0.25410261 |
| 94 | Influenza A_Homo sapiens_hsa05164 | 0.25084166 |
| 95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.23648461 |
| 96 | Morphine addiction_Homo sapiens_hsa05032 | 0.23323460 |
| 97 | Measles_Homo sapiens_hsa05162 | 0.23163361 |
| 98 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.22875984 |
| 99 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.22505250 |
| 100 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.21719259 |

