Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 5.32585061 |
2 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 5.32585061 |
3 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 5.32585061 |
4 | regulation of sister chromatid cohesion (GO:0007063) | 5.20075288 |
5 | positive regulation of chromosome segregation (GO:0051984) | 4.93441905 |
6 | DNA unwinding involved in DNA replication (GO:0006268) | 4.78618444 |
7 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.75924305 |
8 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.61614706 |
9 | DNA strand elongation (GO:0022616) | 4.53169887 |
10 | DNA replication initiation (GO:0006270) | 4.51410956 |
11 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.46889401 |
12 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 4.36356125 |
13 | kinetochore organization (GO:0051383) | 4.19474940 |
14 | DNA replication checkpoint (GO:0000076) | 4.07568197 |
15 | telomere maintenance via recombination (GO:0000722) | 4.01058913 |
16 | CENP-A containing nucleosome assembly (GO:0034080) | 4.00604262 |
17 | chromatin remodeling at centromere (GO:0031055) | 3.98735533 |
18 | mitotic recombination (GO:0006312) | 3.94476004 |
19 | positive regulation of cell size (GO:0045793) | 3.92666025 |
20 | nuclear pore complex assembly (GO:0051292) | 3.90488125 |
21 | protein localization to kinetochore (GO:0034501) | 3.90109133 |
22 | nuclear pore organization (GO:0006999) | 3.89978112 |
23 | heterochromatin organization (GO:0070828) | 3.80457889 |
24 | peptidyl-lysine dimethylation (GO:0018027) | 3.79892864 |
25 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.78115909 |
26 | non-recombinational repair (GO:0000726) | 3.76228693 |
27 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.76228693 |
28 | kinetochore assembly (GO:0051382) | 3.72423454 |
29 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.70218309 |
30 | mitotic metaphase plate congression (GO:0007080) | 3.70010071 |
31 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.69214751 |
32 | telomere maintenance via telomere lengthening (GO:0010833) | 3.68842523 |
33 | mitotic nuclear envelope disassembly (GO:0007077) | 3.68542926 |
34 | cellular protein complex localization (GO:0034629) | 3.68386548 |
35 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.67186146 |
36 | ribosomal small subunit assembly (GO:0000028) | 3.66326154 |
37 | DNA replication-independent nucleosome organization (GO:0034724) | 3.65536162 |
38 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.65536162 |
39 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.58387909 |
40 | IMP biosynthetic process (GO:0006188) | 3.58000652 |
41 | protein complex localization (GO:0031503) | 3.56691498 |
42 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.55000880 |
43 | protein localization to chromosome, centromeric region (GO:0071459) | 3.53879203 |
44 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.53518634 |
45 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.52281677 |
46 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.52281677 |
47 | negative regulation of Ras GTPase activity (GO:0034261) | 3.45791876 |
48 | DNA deamination (GO:0045006) | 3.43086190 |
49 | membrane disassembly (GO:0030397) | 3.40634604 |
50 | nuclear envelope disassembly (GO:0051081) | 3.40634604 |
51 | formation of translation preinitiation complex (GO:0001731) | 3.38719755 |
52 | nucleobase biosynthetic process (GO:0046112) | 3.38653412 |
53 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.37800486 |
54 | establishment of mitotic spindle localization (GO:0040001) | 3.34707919 |
55 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 3.33853402 |
56 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.31771703 |
57 | metaphase plate congression (GO:0051310) | 3.30578559 |
58 | chromatin assembly (GO:0031497) | 3.28955424 |
59 | histone exchange (GO:0043486) | 3.28477834 |
60 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.27663290 |
61 | maturation of SSU-rRNA (GO:0030490) | 3.27168571 |
62 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.25451805 |
63 | mitotic chromosome condensation (GO:0007076) | 3.25390277 |
64 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.24683851 |
65 | regulation of mitochondrial translation (GO:0070129) | 3.23441139 |
66 | purine nucleobase biosynthetic process (GO:0009113) | 3.23299093 |
67 | mitochondrial RNA metabolic process (GO:0000959) | 3.22106169 |
68 | establishment of chromosome localization (GO:0051303) | 3.20791572 |
69 | ribosomal small subunit biogenesis (GO:0042274) | 3.20705735 |
70 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.16643615 |
71 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.14965470 |
72 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.13845602 |
73 | diaphragm development (GO:0060539) | 3.12711157 |
74 | protein-DNA complex disassembly (GO:0032986) | 3.12197278 |
75 | nucleosome disassembly (GO:0006337) | 3.12197278 |
76 | DNA topological change (GO:0006265) | 3.12036553 |
77 | L-serine metabolic process (GO:0006563) | 3.11962103 |
78 | establishment of mitotic spindle orientation (GO:0000132) | 3.10233196 |
79 | ATP-dependent chromatin remodeling (GO:0043044) | 3.08647919 |
80 | viral mRNA export from host cell nucleus (GO:0046784) | 3.08554173 |
81 | CTP metabolic process (GO:0046036) | 3.07901353 |
82 | CTP biosynthetic process (GO:0006241) | 3.07901353 |
83 | IMP metabolic process (GO:0046040) | 3.06730819 |
84 | regulation of translational fidelity (GO:0006450) | 3.06698635 |
85 | mitotic sister chromatid segregation (GO:0000070) | 3.06112019 |
86 | chromatin silencing (GO:0006342) | 3.05044501 |
87 | histone arginine methylation (GO:0034969) | 3.04581732 |
88 | skeletal muscle organ development (GO:0060538) | 3.04528452 |
89 | spliceosomal snRNP assembly (GO:0000387) | 3.04268662 |
90 | DNA duplex unwinding (GO:0032508) | 3.03772660 |
91 | sister chromatid segregation (GO:0000819) | 3.03555034 |
92 | DNA geometric change (GO:0032392) | 3.03554832 |
93 | pore complex assembly (GO:0046931) | 3.03040727 |
94 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 3.02239962 |
95 | translesion synthesis (GO:0019985) | 3.01522846 |
96 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.99755994 |
97 | negative regulation of sister chromatid segregation (GO:0033046) | 2.99755994 |
98 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.99755994 |
99 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.99755994 |
100 | mismatch repair (GO:0006298) | 2.99308828 |
101 | negative regulation of RNA splicing (GO:0033119) | 2.98139976 |
102 | meiotic chromosome segregation (GO:0045132) | 2.97986106 |
103 | negative regulation of chromosome segregation (GO:0051985) | 2.97532845 |
104 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.95141330 |
105 | histone H2A acetylation (GO:0043968) | 2.94206825 |
106 | spindle checkpoint (GO:0031577) | 2.94030816 |
107 | RNA splicing, via transesterification reactions (GO:0000375) | 2.93882143 |
108 | spindle assembly checkpoint (GO:0071173) | 2.92899528 |
109 | chromatin assembly or disassembly (GO:0006333) | 2.92879929 |
110 | ribosome biogenesis (GO:0042254) | 2.92757941 |
111 | termination of RNA polymerase II transcription (GO:0006369) | 2.92533552 |
112 | telomere maintenance (GO:0000723) | 2.92217996 |
113 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.92091682 |
114 | mRNA splicing, via spliceosome (GO:0000398) | 2.92091682 |
115 | dosage compensation (GO:0007549) | 2.91454252 |
116 | telomere organization (GO:0032200) | 2.91245778 |
117 | mitotic spindle assembly checkpoint (GO:0007094) | 2.90317624 |
118 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.89664027 |
119 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.89455939 |
120 | regulation of helicase activity (GO:0051095) | 2.89362247 |
121 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.88994750 |
122 | ncRNA 3-end processing (GO:0043628) | 2.88648349 |
123 | positive regulation of receptor biosynthetic process (GO:0010870) | 2.88300252 |
124 | regulation of spindle organization (GO:0090224) | 2.87607813 |
125 | establishment of integrated proviral latency (GO:0075713) | 2.84644275 |
126 | tetrahydrofolate metabolic process (GO:0046653) | 2.84443857 |
127 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.84397292 |
128 | UMP biosynthetic process (GO:0006222) | 2.84397292 |
129 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.84397292 |
130 | UMP metabolic process (GO:0046049) | 2.84397292 |
131 | mitotic spindle checkpoint (GO:0071174) | 2.84346707 |
132 | histone mRNA metabolic process (GO:0008334) | 2.83356928 |
133 | spliceosomal complex assembly (GO:0000245) | 2.82905330 |
134 | peptidyl-arginine N-methylation (GO:0035246) | 2.82596693 |
135 | peptidyl-arginine methylation (GO:0018216) | 2.82596693 |
136 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.82346717 |
137 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.81577884 |
138 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 2.81502468 |
139 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.80706579 |
140 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.80706579 |
141 | postreplication repair (GO:0006301) | 2.80599414 |
142 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.79476431 |
143 | regulation of chromosome segregation (GO:0051983) | 2.79443038 |
144 | negative regulation of mRNA processing (GO:0050686) | 2.76718928 |
145 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.76354534 |
146 | protein prenylation (GO:0018342) | 2.76265838 |
147 | prenylation (GO:0097354) | 2.76265838 |
148 | intra-S DNA damage checkpoint (GO:0031573) | 2.76034456 |
149 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.75189498 |
150 | DNA ligation (GO:0006266) | 2.74386943 |
151 | regulation of sister chromatid segregation (GO:0033045) | 2.73804180 |
152 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.73804180 |
153 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.73804180 |
154 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.73303107 |
155 | rRNA processing (GO:0006364) | 2.71237320 |
156 | organ growth (GO:0035265) | 2.69529427 |
157 | pyrimidine nucleotide biosynthetic process (GO:0006221) | 2.67270796 |
158 | establishment of spindle localization (GO:0051293) | 2.66216124 |
159 | histone H3-K9 methylation (GO:0051567) | 2.66026070 |
160 | establishment of spindle orientation (GO:0051294) | 2.65625635 |
161 | adenine nucleotide transport (GO:0051503) | 2.63121805 |
162 | coenzyme A biosynthetic process (GO:0015937) | 2.60422597 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.31479501 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.26304653 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.17455343 |
4 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.47108430 |
5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.34977550 |
6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.96824162 |
7 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.86804855 |
8 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.86747547 |
9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.70560889 |
10 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.62917867 |
11 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.62426983 |
12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.50847714 |
13 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.49600149 |
14 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.49462134 |
15 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.36149756 |
16 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.35660610 |
17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.33099568 |
18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.32289375 |
19 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.30354409 |
20 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.28911064 |
21 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.28335585 |
22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.28133170 |
23 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.15975855 |
24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.14632970 |
25 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.14109574 |
26 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.13233802 |
27 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.09056481 |
28 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.0771205 |
29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98643309 |
30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.92753262 |
31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.91519410 |
32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.91504948 |
33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.90008777 |
34 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.88704118 |
35 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.88351239 |
36 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.87972208 |
37 | GATA1_22025678_ChIP-Seq_K562_Human | 1.86496953 |
38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.85778860 |
39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84268548 |
40 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.82669625 |
41 | MYC_22102868_ChIP-Seq_BL_Human | 1.79611082 |
42 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.75174560 |
43 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.71182461 |
44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.69944914 |
45 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.69861466 |
46 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.69202551 |
47 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.63483017 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.62945698 |
49 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.62811776 |
50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.62323600 |
51 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.59069045 |
52 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.57821297 |
53 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55903579 |
54 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.54516864 |
55 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.53984248 |
56 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.46825763 |
57 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.46086377 |
58 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.42545642 |
59 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.42537369 |
60 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.40884037 |
61 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.35642665 |
62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35451151 |
63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.29867283 |
64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.28726914 |
65 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.27450847 |
66 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.27268323 |
67 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.26899819 |
68 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.25134376 |
69 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.23850014 |
70 | * YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.21449958 |
71 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20736487 |
72 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.19454701 |
73 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.18864911 |
74 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.18109498 |
75 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.17892657 |
76 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.16185069 |
77 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 1.16086178 |
78 | P68_20966046_ChIP-Seq_HELA_Human | 1.15906655 |
79 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.14638516 |
80 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.14163028 |
81 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12697651 |
82 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.12451652 |
83 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.11584931 |
84 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.09502032 |
85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.08824569 |
86 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.08164777 |
87 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.07468463 |
88 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.07468463 |
89 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.07468463 |
90 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.06803974 |
91 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.02944934 |
92 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.02898306 |
93 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02616667 |
94 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.01596183 |
95 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.99402068 |
96 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.98815167 |
97 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.98354916 |
98 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.97018705 |
99 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.96513823 |
100 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.96323959 |
101 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.95977896 |
102 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.94994135 |
103 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.94606905 |
104 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.93005932 |
105 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.92896206 |
106 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.92689254 |
107 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.90715764 |
108 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.90183191 |
109 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89205364 |
110 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.89169427 |
111 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.89022690 |
112 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.88306250 |
113 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.85772745 |
114 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.84593546 |
115 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.84530803 |
116 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.84035521 |
117 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.83408387 |
118 | KAP1_27257070_Chip-Seq_ESCs_Mouse | 0.83002654 |
119 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.82497169 |
120 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.82308753 |
121 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.81562227 |
122 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.81231173 |
123 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.80620321 |
124 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.80119879 |
125 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.79424845 |
126 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.78184640 |
127 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.77874502 |
128 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.77602505 |
129 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.76584450 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.41577945 |
2 | MP0010094_abnormal_chromosome_stability | 4.29247361 |
3 | MP0003111_abnormal_nucleus_morphology | 3.82400240 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.75137436 |
5 | MP0008057_abnormal_DNA_replication | 3.66375751 |
6 | MP0003077_abnormal_cell_cycle | 3.59674878 |
7 | MP0008007_abnormal_cellular_replicative | 3.19102936 |
8 | MP0003123_paternal_imprinting | 3.13422601 |
9 | MP0002234_abnormal_pharynx_morphology | 3.12061712 |
10 | MP0008058_abnormal_DNA_repair | 2.86451714 |
11 | MP0004858_abnormal_nervous_system | 2.74528313 |
12 | MP0008932_abnormal_embryonic_tissue | 2.46453489 |
13 | MP0004233_abnormal_muscle_weight | 2.44597343 |
14 | MP0000467_abnormal_esophagus_morphology | 2.25942089 |
15 | MP0002396_abnormal_hematopoietic_system | 2.24534165 |
16 | MP0001919_abnormal_reproductive_system | 2.21155637 |
17 | MP0002009_preneoplasia | 2.13914697 |
18 | * MP0000350_abnormal_cell_proliferation | 2.12920848 |
19 | MP0003646_muscle_fatigue | 2.06910152 |
20 | MP0005645_abnormal_hypothalamus_physiol | 2.03961492 |
21 | MP0010352_gastrointestinal_tract_polyps | 2.03557583 |
22 | MP0001730_embryonic_growth_arrest | 2.03287152 |
23 | MP0003121_genomic_imprinting | 1.94563854 |
24 | MP0010030_abnormal_orbit_morphology | 1.77306376 |
25 | MP0008877_abnormal_DNA_methylation | 1.73362282 |
26 | MP0004197_abnormal_fetal_growth/weight/ | 1.66328154 |
27 | MP0001697_abnormal_embryo_size | 1.64628420 |
28 | MP0000534_abnormal_ureter_morphology | 1.64343887 |
29 | * MP0001672_abnormal_embryogenesis/_devel | 1.61641286 |
30 | * MP0005380_embryogenesis_phenotype | 1.61641286 |
31 | * MP0000490_abnormal_crypts_of | 1.60704357 |
32 | MP0003567_abnormal_fetal_cardiomyocyte | 1.58699696 |
33 | MP0003890_abnormal_embryonic-extraembry | 1.57452381 |
34 | MP0003315_abnormal_perineum_morphology | 1.54372089 |
35 | MP0004808_abnormal_hematopoietic_stem | 1.51103383 |
36 | MP0003786_premature_aging | 1.50693563 |
37 | * MP0002085_abnormal_embryonic_tissue | 1.49985342 |
38 | MP0001346_abnormal_lacrimal_gland | 1.48333239 |
39 | * MP0003984_embryonic_growth_retardation | 1.47342603 |
40 | * MP0002088_abnormal_embryonic_growth/wei | 1.44882751 |
41 | MP0002084_abnormal_developmental_patter | 1.42246106 |
42 | * MP0002080_prenatal_lethality | 1.37134797 |
43 | MP0000537_abnormal_urethra_morphology | 1.36760786 |
44 | MP0002249_abnormal_larynx_morphology | 1.34057336 |
45 | MP0005076_abnormal_cell_differentiation | 1.33712011 |
46 | * MP0000313_abnormal_cell_death | 1.33678407 |
47 | MP0009053_abnormal_anal_canal | 1.31484401 |
48 | MP0001293_anophthalmia | 1.30846350 |
49 | MP0003941_abnormal_skin_development | 1.30831630 |
50 | * MP0002086_abnormal_extraembryonic_tissu | 1.28650163 |
51 | MP0003119_abnormal_digestive_system | 1.27571938 |
52 | MP0002877_abnormal_melanocyte_morpholog | 1.26545320 |
53 | MP0010307_abnormal_tumor_latency | 1.25578114 |
54 | MP0004185_abnormal_adipocyte_glucose | 1.24578939 |
55 | MP0006054_spinal_hemorrhage | 1.23148627 |
56 | MP0002019_abnormal_tumor_incidence | 1.21928768 |
57 | MP0003283_abnormal_digestive_organ | 1.18056133 |
58 | MP0002938_white_spotting | 1.15746621 |
59 | MP0003303_peritoneal_inflammation | 1.14769518 |
60 | MP0000631_abnormal_neuroendocrine_gland | 1.14275855 |
61 | * MP0000703_abnormal_thymus_morphology | 1.12117900 |
62 | * MP0003763_abnormal_thymus_physiology | 1.11642441 |
63 | MP0000049_abnormal_middle_ear | 1.11414941 |
64 | MP0009250_abnormal_appendicular_skeleto | 1.07854196 |
65 | * MP0002398_abnormal_bone_marrow | 1.07354380 |
66 | MP0002653_abnormal_ependyma_morphology | 1.07286631 |
67 | MP0004133_heterotaxia | 1.07121840 |
68 | MP0002233_abnormal_nose_morphology | 1.06140642 |
69 | MP0009333_abnormal_splenocyte_physiolog | 1.05524644 |
70 | MP0002697_abnormal_eye_size | 1.03077872 |
71 | * MP0002116_abnormal_craniofacial_bone | 1.02673361 |
72 | MP0009697_abnormal_copulation | 1.02231125 |
73 | MP0005499_abnormal_olfactory_system | 1.02190519 |
74 | MP0002210_abnormal_sex_determination | 1.02133519 |
75 | MP0010368_abnormal_lymphatic_system | 1.00940716 |
76 | MP0000858_altered_metastatic_potential | 1.00690261 |
77 | MP0008789_abnormal_olfactory_epithelium | 0.99797429 |
78 | MP0005197_abnormal_uvea_morphology | 0.99355653 |
79 | MP0001348_abnormal_lacrimal_gland | 0.95985576 |
80 | MP0006292_abnormal_olfactory_placode | 0.94619724 |
81 | MP0005623_abnormal_meninges_morphology | 0.93580881 |
82 | * MP0002722_abnormal_immune_system | 0.91615235 |
83 | MP0002163_abnormal_gland_morphology | 0.90953150 |
84 | MP0001661_extended_life_span | 0.90602675 |
85 | MP0001663_abnormal_digestive_system | 0.88895796 |
86 | MP0002111_abnormal_tail_morphology | 0.88863982 |
87 | MP0002160_abnormal_reproductive_system | 0.87059514 |
88 | MP0000428_abnormal_craniofacial_morphol | 0.86720136 |
89 | MP0001286_abnormal_eye_development | 0.86661036 |
90 | MP0003942_abnormal_urinary_system | 0.86420508 |
91 | MP0001545_abnormal_hematopoietic_system | 0.86386289 |
92 | MP0005397_hematopoietic_system_phenotyp | 0.86386289 |
93 | MP0000358_abnormal_cell_content/ | 0.85307750 |
94 | * MP0003115_abnormal_respiratory_system | 0.85122513 |
95 | MP0002089_abnormal_postnatal_growth/wei | 0.85098529 |
96 | MP0001145_abnormal_male_reproductive | 0.84601162 |
97 | MP0003122_maternal_imprinting | 0.84544517 |
98 | * MP0001119_abnormal_female_reproductive | 0.84328678 |
99 | MP0003705_abnormal_hypodermis_morpholog | 0.82563363 |
100 | MP0000955_abnormal_spinal_cord | 0.82520794 |
101 | * MP0000689_abnormal_spleen_morphology | 0.82239416 |
102 | * MP0002429_abnormal_blood_cell | 0.81707556 |
103 | MP0003385_abnormal_body_wall | 0.81156917 |
104 | MP0000778_abnormal_nervous_system | 0.80928380 |
105 | MP0002184_abnormal_innervation | 0.80710557 |
106 | MP0001915_intracranial_hemorrhage | 0.80560512 |
107 | * MP0003937_abnormal_limbs/digits/tail_de | 0.80001452 |
108 | MP0000516_abnormal_urinary_system | 0.79523859 |
109 | MP0005367_renal/urinary_system_phenotyp | 0.79523859 |
110 | MP0002081_perinatal_lethality | 0.79247855 |
111 | * MP0002109_abnormal_limb_morphology | 0.78450975 |
112 | MP0002006_tumorigenesis | 0.77286569 |
113 | MP0002751_abnormal_autonomic_nervous | 0.76524983 |
114 | MP0009672_abnormal_birth_weight | 0.76282471 |
115 | MP0000733_abnormal_muscle_development | 0.75573454 |
116 | MP0000678_abnormal_parathyroid_gland | 0.73690508 |
117 | MP0009278_abnormal_bone_marrow | 0.73621857 |
118 | MP0002161_abnormal_fertility/fecundity | 0.72804953 |
119 | MP0002282_abnormal_trachea_morphology | 0.72568077 |
120 | * MP0000716_abnormal_immune_system | 0.72378738 |
121 | MP0003943_abnormal_hepatobiliary_system | 0.72135867 |
122 | MP0003755_abnormal_palate_morphology | 0.71271870 |
123 | MP0003935_abnormal_craniofacial_develop | 0.71158496 |
124 | MP0005075_abnormal_melanosome_morpholog | 0.70117320 |
125 | MP0002925_abnormal_cardiovascular_devel | 0.70060393 |
126 | MP0002932_abnormal_joint_morphology | 0.69476832 |
127 | MP0005671_abnormal_response_to | 0.68863215 |
128 | MP0002095_abnormal_skin_pigmentation | 0.68300669 |
129 | MP0000653_abnormal_sex_gland | 0.67876924 |
130 | MP0003861_abnormal_nervous_system | 0.67595574 |
131 | * MP0000432_abnormal_head_morphology | 0.66321550 |
132 | MP0003448_altered_tumor_morphology | 0.65242250 |
133 | MP0003718_maternal_effect | 0.64257467 |
134 | MP0001929_abnormal_gametogenesis | 0.64131402 |
135 | MP0005389_reproductive_system_phenotype | 0.63992873 |
136 | MP0002405_respiratory_system_inflammati | 0.63724946 |
137 | MP0002092_abnormal_eye_morphology | 0.63645276 |
138 | MP0005384_cellular_phenotype | 0.63291706 |
139 | MP0001835_abnormal_antigen_presentation | 0.62580442 |
140 | MP0005394_taste/olfaction_phenotype | 0.62511693 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.14008484 |
2 | Abnormality of the anterior horn cell (HP:0006802) | 3.86235835 |
3 | Degeneration of anterior horn cells (HP:0002398) | 3.86235835 |
4 | Progressive muscle weakness (HP:0003323) | 3.83198257 |
5 | Ureteral stenosis (HP:0000071) | 3.81039285 |
6 | Abnormality of the renal collecting system (HP:0004742) | 3.50046258 |
7 | Hyperacusis (HP:0010780) | 3.34260714 |
8 | Ureteral obstruction (HP:0006000) | 3.33134577 |
9 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.26599879 |
10 | Acute lymphatic leukemia (HP:0006721) | 3.25533179 |
11 | Chromsome breakage (HP:0040012) | 3.16030144 |
12 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 3.15595732 |
13 | Reticulocytopenia (HP:0001896) | 3.15451445 |
14 | 11 pairs of ribs (HP:0000878) | 3.11791407 |
15 | Patellar aplasia (HP:0006443) | 3.06856638 |
16 | Short 5th finger (HP:0009237) | 3.05236155 |
17 | Colon cancer (HP:0003003) | 3.04087993 |
18 | Meckel diverticulum (HP:0002245) | 3.01721175 |
19 | Selective tooth agenesis (HP:0001592) | 3.00900510 |
20 | Sparse lateral eyebrow (HP:0005338) | 2.94718544 |
21 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.94601301 |
22 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.92034784 |
23 | Abnormality of the ileum (HP:0001549) | 2.91190493 |
24 | Abnormality of chromosome stability (HP:0003220) | 2.85165230 |
25 | Insomnia (HP:0100785) | 2.81623396 |
26 | Anal stenosis (HP:0002025) | 2.79644368 |
27 | Long foot (HP:0001833) | 2.79356029 |
28 | Abnormality of cochlea (HP:0000375) | 2.79347326 |
29 | Short 4th metacarpal (HP:0010044) | 2.78301915 |
30 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.78301915 |
31 | Medulloblastoma (HP:0002885) | 2.73335820 |
32 | Abnormality of the fingertips (HP:0001211) | 2.71373518 |
33 | Lip pit (HP:0100267) | 2.70190198 |
34 | Abnormality of the preputium (HP:0100587) | 2.64651613 |
35 | Hypoplastic pelvis (HP:0008839) | 2.64439742 |
36 | Oral leukoplakia (HP:0002745) | 2.62716865 |
37 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.62672061 |
38 | Abnormal number of incisors (HP:0011064) | 2.61587653 |
39 | Ectopic kidney (HP:0000086) | 2.59309338 |
40 | Carpal bone hypoplasia (HP:0001498) | 2.58558014 |
41 | Aplastic anemia (HP:0001915) | 2.54747666 |
42 | Absent radius (HP:0003974) | 2.50790238 |
43 | Breast hypoplasia (HP:0003187) | 2.49951023 |
44 | Overriding aorta (HP:0002623) | 2.47324382 |
45 | Morphological abnormality of the inner ear (HP:0011390) | 2.44055746 |
46 | Absent thumb (HP:0009777) | 2.44047823 |
47 | Abnormal lung lobation (HP:0002101) | 2.43000237 |
48 | Transposition of the great arteries (HP:0001669) | 2.40779576 |
49 | Abnormal connection of the cardiac segments (HP:0011545) | 2.40779576 |
50 | Abnormal ventriculo-arterial connection (HP:0011563) | 2.40779576 |
51 | Elfin facies (HP:0004428) | 2.40115508 |
52 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.37208994 |
53 | Small intestinal stenosis (HP:0012848) | 2.37069492 |
54 | Duodenal stenosis (HP:0100867) | 2.37069492 |
55 | Optic nerve coloboma (HP:0000588) | 2.36328767 |
56 | Premature graying of hair (HP:0002216) | 2.36173596 |
57 | Aplasia involving forearm bones (HP:0009822) | 2.31015826 |
58 | Absent forearm bone (HP:0003953) | 2.31015826 |
59 | Abnormality of alanine metabolism (HP:0010916) | 2.29537145 |
60 | Hyperalaninemia (HP:0003348) | 2.29537145 |
61 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.29537145 |
62 | Ureteral duplication (HP:0000073) | 2.27495642 |
63 | Spinal cord lesions (HP:0100561) | 2.26643371 |
64 | Syringomyelia (HP:0003396) | 2.26643371 |
65 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.25196000 |
66 | Trismus (HP:0000211) | 2.25107737 |
67 | Missing ribs (HP:0000921) | 2.25035157 |
68 | Embryonal renal neoplasm (HP:0011794) | 2.24255861 |
69 | Triphalangeal thumb (HP:0001199) | 2.23994219 |
70 | Self-mutilation (HP:0000742) | 2.21173911 |
71 | Myelodysplasia (HP:0002863) | 2.20467268 |
72 | Ependymoma (HP:0002888) | 2.17647687 |
73 | Autoimmune thrombocytopenia (HP:0001973) | 2.15507635 |
74 | Bone marrow hypocellularity (HP:0005528) | 2.15393788 |
75 | Duplication of thumb phalanx (HP:0009942) | 2.14300273 |
76 | Partial agenesis of the corpus callosum (HP:0001338) | 2.14050094 |
77 | Broad thumb (HP:0011304) | 2.10941760 |
78 | Fibular aplasia (HP:0002990) | 2.10698426 |
79 | Abnormal number of erythroid precursors (HP:0012131) | 2.10224972 |
80 | Preauricular pit (HP:0004467) | 2.09851767 |
81 | Periauricular skin pits (HP:0100277) | 2.09851767 |
82 | Agnosia (HP:0010524) | 2.09769618 |
83 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.08659031 |
84 | Deviation of the thumb (HP:0009603) | 2.08527980 |
85 | Atresia of the external auditory canal (HP:0000413) | 2.07724282 |
86 | Neoplasm of the pancreas (HP:0002894) | 2.07541059 |
87 | Rough bone trabeculation (HP:0100670) | 2.04497658 |
88 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.03911297 |
89 | Proximal placement of thumb (HP:0009623) | 2.01369481 |
90 | Supernumerary spleens (HP:0009799) | 2.01241591 |
91 | Horseshoe kidney (HP:0000085) | 2.00294938 |
92 | Cortical dysplasia (HP:0002539) | 2.00178006 |
93 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.00059618 |
94 | Tracheoesophageal fistula (HP:0002575) | 1.99552261 |
95 | Lymphoma (HP:0002665) | 1.99519779 |
96 | Cleft eyelid (HP:0000625) | 1.98955271 |
97 | Facial cleft (HP:0002006) | 1.98831425 |
98 | Abnormality of the duodenum (HP:0002246) | 1.97695001 |
99 | Increased nuchal translucency (HP:0010880) | 1.97321385 |
100 | Cellular immunodeficiency (HP:0005374) | 1.97003532 |
101 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.96634937 |
102 | Short middle phalanx of the 5th finger (HP:0004220) | 1.95275959 |
103 | Type I transferrin isoform profile (HP:0003642) | 1.95192095 |
104 | Posterior embryotoxon (HP:0000627) | 1.89116821 |
105 | Abnormality of the carotid arteries (HP:0005344) | 1.88826592 |
106 | Renal duplication (HP:0000075) | 1.87941398 |
107 | Polymicrogyria (HP:0002126) | 1.85912573 |
108 | Amaurosis fugax (HP:0100576) | 1.85586483 |
109 | Sloping forehead (HP:0000340) | 1.85030220 |
110 | Volvulus (HP:0002580) | 1.82127416 |
111 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.81295045 |
112 | Rectal fistula (HP:0100590) | 1.81096437 |
113 | Rectovaginal fistula (HP:0000143) | 1.81096437 |
114 | Abnormality of the calcaneus (HP:0008364) | 1.80233680 |
115 | Brushfield spots (HP:0001088) | 1.79513528 |
116 | Coarctation of aorta (HP:0001680) | 1.78717110 |
117 | Tetralogy of Fallot (HP:0001636) | 1.78505878 |
118 | Abnormally folded helix (HP:0008544) | 1.78434416 |
119 | Broad distal phalanx of finger (HP:0009836) | 1.78042354 |
120 | Rhabdomyosarcoma (HP:0002859) | 1.77251765 |
121 | Squamous cell carcinoma (HP:0002860) | 1.76478996 |
122 | Abdominal situs inversus (HP:0003363) | 1.76375634 |
123 | Abnormality of abdominal situs (HP:0011620) | 1.76375634 |
124 | Flat face (HP:0012368) | 1.74895806 |
125 | Overfolded helix (HP:0000396) | 1.74148035 |
126 | Preauricular skin tag (HP:0000384) | 1.74123412 |
127 | Severe muscular hypotonia (HP:0006829) | 1.74085818 |
128 | Prominent metopic ridge (HP:0005487) | 1.74045609 |
129 | Aplasia/Hypoplasia of the nipples (HP:0006709) | 1.74040929 |
130 | Renovascular hypertension (HP:0100817) | 1.73849142 |
131 | Slender long bone (HP:0003100) | 1.73289258 |
132 | Stenosis of the external auditory canal (HP:0000402) | 1.73181436 |
133 | High anterior hairline (HP:0009890) | 1.72157027 |
134 | Unilateral renal agenesis (HP:0000122) | 1.71906994 |
135 | Abnormality of the metopic suture (HP:0005556) | 1.71485245 |
136 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.71235347 |
137 | Clubbing of toes (HP:0100760) | 1.71010803 |
138 | Concave nail (HP:0001598) | 1.70855095 |
139 | IgM deficiency (HP:0002850) | 1.70784230 |
140 | Septate vagina (HP:0001153) | 1.70414595 |
141 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.69591672 |
142 | Aplasia of the phalanges of the hand (HP:0009802) | 1.69591672 |
143 | Aplasia involving bones of the extremities (HP:0009825) | 1.69591672 |
144 | Broad phalanges of the hand (HP:0009768) | 1.68469810 |
145 | Trigonocephaly (HP:0000243) | 1.68355095 |
146 | Abnormality of the 4th metacarpal (HP:0010012) | 1.68353456 |
147 | Intestinal fistula (HP:0100819) | 1.68139887 |
148 | Long eyelashes (HP:0000527) | 1.68020006 |
149 | Broad palm (HP:0001169) | 1.67296873 |
150 | Long palpebral fissure (HP:0000637) | 1.66734486 |
151 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.65973977 |
152 | Broad hallux (HP:0010055) | 1.65619558 |
153 | Thrombocytosis (HP:0001894) | 1.65588793 |
154 | Pallor (HP:0000980) | 1.65509068 |
155 | Short thumb (HP:0009778) | 1.64890098 |
156 | Basal cell carcinoma (HP:0002671) | 1.64709430 |
157 | Cerebral hypomyelination (HP:0006808) | 1.64657983 |
158 | Patellar dislocation (HP:0002999) | 1.64200687 |
159 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.63845576 |
160 | Duplicated collecting system (HP:0000081) | 1.63832998 |
161 | Abnormality of the line of Schwalbe (HP:0008048) | 1.63577077 |
162 | Abnormality of reticulocytes (HP:0004312) | 1.63247858 |
163 | Pointed chin (HP:0000307) | 1.63000689 |
164 | Microretrognathia (HP:0000308) | 1.61578841 |
165 | Diastasis recti (HP:0001540) | 1.60890146 |
166 | Impulsivity (HP:0100710) | 1.60711340 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.26719947 |
2 | BUB1 | 4.18288279 |
3 | WEE1 | 3.51326258 |
4 | EIF2AK1 | 3.43644937 |
5 | SRPK1 | 3.30845738 |
6 | EEF2K | 3.26132475 |
7 | MAP3K3 | 2.89811256 |
8 | WNK4 | 2.78354441 |
9 | MKNK1 | 2.51028879 |
10 | NEK2 | 2.49343276 |
11 | ACVR1B | 2.48200268 |
12 | SMG1 | 2.29211788 |
13 | TESK2 | 2.10827288 |
14 | BRSK2 | 2.10325832 |
15 | TAOK1 | 2.10264884 |
16 | VRK1 | 2.08225276 |
17 | PASK | 2.07671127 |
18 | NEK1 | 2.07516359 |
19 | MAP2K3 | 2.04549322 |
20 | VRK2 | 2.03263310 |
21 | TGFBR1 | 2.01630114 |
22 | EIF2AK3 | 1.96493354 |
23 | ATR | 1.94707848 |
24 | CDK12 | 1.85976847 |
25 | PLK3 | 1.85309239 |
26 | TTK | 1.84993958 |
27 | RPS6KA4 | 1.83772447 |
28 | TLK1 | 1.81478231 |
29 | PLK1 | 1.80165425 |
30 | STK39 | 1.73264563 |
31 | MKNK2 | 1.72570551 |
32 | CDK7 | 1.66844926 |
33 | TSSK6 | 1.64620137 |
34 | PLK4 | 1.63589107 |
35 | ZAK | 1.62659985 |
36 | AURKB | 1.54534308 |
37 | NME2 | 1.50014568 |
38 | BRSK1 | 1.48806077 |
39 | MAP3K10 | 1.47651675 |
40 | TESK1 | 1.41461773 |
41 | TRIB3 | 1.34958328 |
42 | BCKDK | 1.27026278 |
43 | * CHEK2 | 1.26699973 |
44 | SCYL2 | 1.25663985 |
45 | DYRK3 | 1.22316044 |
46 | CHEK1 | 1.22044152 |
47 | BRD4 | 1.21862306 |
48 | ICK | 1.21524454 |
49 | CDK8 | 1.20833164 |
50 | CLK1 | 1.15458615 |
51 | AURKA | 1.12846134 |
52 | ERBB3 | 1.12694461 |
53 | CDK4 | 1.12014489 |
54 | RPS6KB2 | 1.11703735 |
55 | EIF2AK2 | 1.10968126 |
56 | STK4 | 1.09038447 |
57 | TAF1 | 1.01658992 |
58 | MAPKAPK5 | 1.00321287 |
59 | STK10 | 0.97558554 |
60 | MAP3K8 | 0.95691393 |
61 | PBK | 0.94782525 |
62 | STK16 | 0.93078844 |
63 | MELK | 0.91346316 |
64 | CCNB1 | 0.91023468 |
65 | ATM | 0.88571131 |
66 | ABL2 | 0.87564494 |
67 | CSNK1G3 | 0.86278276 |
68 | SIK3 | 0.86133514 |
69 | ARAF | 0.85872174 |
70 | KDR | 0.83759293 |
71 | IRAK4 | 0.82616130 |
72 | * CDK2 | 0.81973941 |
73 | PIM1 | 0.81244671 |
74 | BMPR1B | 0.79961843 |
75 | PAK4 | 0.78968568 |
76 | DYRK1A | 0.78633823 |
77 | MAP3K9 | 0.77386720 |
78 | CDK6 | 0.75712911 |
79 | TXK | 0.75112231 |
80 | PNCK | 0.73627368 |
81 | LIMK1 | 0.72948840 |
82 | CDK9 | 0.70945281 |
83 | NTRK2 | 0.70740369 |
84 | NUAK1 | 0.70692177 |
85 | CSNK1A1L | 0.69406783 |
86 | MAPK11 | 0.68397692 |
87 | PIM2 | 0.68155438 |
88 | YES1 | 0.67868085 |
89 | CSNK1G1 | 0.66368060 |
90 | LATS2 | 0.65601303 |
91 | BCR | 0.63177678 |
92 | * CDK1 | 0.62525035 |
93 | CSNK2A1 | 0.62070827 |
94 | PAK1 | 0.60524780 |
95 | TAOK2 | 0.59565267 |
96 | CAMK1D | 0.59489903 |
97 | RPS6KA6 | 0.58618964 |
98 | IRAK3 | 0.57491274 |
99 | EPHA2 | 0.56042657 |
100 | MAP4K1 | 0.55692457 |
101 | CSNK2A2 | 0.55267134 |
102 | TYRO3 | 0.55238579 |
103 | FLT3 | 0.54541902 |
104 | CHUK | 0.54414578 |
105 | WNK1 | 0.54392992 |
106 | RPS6KL1 | 0.54189043 |
107 | RPS6KC1 | 0.54189043 |
108 | PINK1 | 0.53031370 |
109 | CDK11A | 0.52999006 |
110 | PRKCQ | 0.51763666 |
111 | BTK | 0.49990579 |
112 | RPS6KA5 | 0.48600550 |
113 | CAMK1G | 0.48024986 |
114 | CDK15 | 0.47929736 |
115 | STK3 | 0.47860965 |
116 | CSNK1G2 | 0.46637661 |
117 | STK38L | 0.45206903 |
118 | BRAF | 0.45190233 |
119 | MTOR | 0.44164168 |
120 | DYRK2 | 0.43383526 |
121 | CDK18 | 0.41933143 |
122 | FGFR1 | 0.41773359 |
123 | LRRK2 | 0.41596353 |
124 | PRKCI | 0.39177425 |
125 | MAP3K11 | 0.38937461 |
126 | CAMK4 | 0.38035107 |
127 | ALK | 0.38024931 |
128 | CDK19 | 0.37751985 |
129 | NEK9 | 0.36248170 |
130 | NLK | 0.35709787 |
131 | CDK14 | 0.34878517 |
132 | TEC | 0.34563458 |
133 | NTRK1 | 0.33564292 |
134 | MAP3K2 | 0.32406031 |
135 | KSR2 | 0.30872437 |
136 | AKT1 | 0.30553813 |
137 | PRKDC | 0.29200475 |
138 | CSNK1E | 0.28627960 |
139 | MAP3K14 | 0.28530008 |
140 | MAP3K1 | 0.28082442 |
141 | MAP3K5 | 0.27023299 |
142 | ZAP70 | 0.26875879 |
143 | KSR1 | 0.26171648 |
144 | AKT2 | 0.25716311 |
145 | STK24 | 0.24656879 |
146 | KIT | 0.24542837 |
147 | * MAPK14 | 0.24167309 |
148 | ILK | 0.21640457 |
149 | AKT3 | 0.20285775 |
150 | MAPKAPK2 | 0.19328872 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.75752480 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.03374036 |
3 | Spliceosome_Homo sapiens_hsa03040 | 3.29907508 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.11677892 |
5 | Homologous recombination_Homo sapiens_hsa03440 | 3.03754671 |
6 | Base excision repair_Homo sapiens_hsa03410 | 2.95711203 |
7 | Cell cycle_Homo sapiens_hsa04110 | 2.83070124 |
8 | RNA transport_Homo sapiens_hsa03013 | 2.78480994 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.69944855 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.62160924 |
11 | Ribosome_Homo sapiens_hsa03010 | 2.58415927 |
12 | Sulfur relay system_Homo sapiens_hsa04122 | 2.47057548 |
13 | RNA polymerase_Homo sapiens_hsa03020 | 2.35821837 |
14 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.25984442 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.15570991 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.14102116 |
17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.05276247 |
18 | RNA degradation_Homo sapiens_hsa03018 | 2.03440598 |
19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.96943004 |
20 | Lysine degradation_Homo sapiens_hsa00310 | 1.96716462 |
21 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.96561681 |
22 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.91837100 |
23 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.77809927 |
24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.70433849 |
25 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.64357265 |
26 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.57511969 |
27 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.37696305 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.35009855 |
29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.29615226 |
30 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.28546348 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.22608212 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.22338762 |
33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.22126397 |
34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20371231 |
35 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.16021144 |
36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.11878557 |
37 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.11780583 |
38 | Carbon metabolism_Homo sapiens_hsa01200 | 1.10550656 |
39 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.07655203 |
40 | HTLV-I infection_Homo sapiens_hsa05166 | 1.07264584 |
41 | Purine metabolism_Homo sapiens_hsa00230 | 1.04279076 |
42 | Legionellosis_Homo sapiens_hsa05134 | 1.04039645 |
43 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.02765913 |
44 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.00334652 |
45 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.92635730 |
46 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.88136940 |
47 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.88035978 |
48 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.87512861 |
49 | Thyroid cancer_Homo sapiens_hsa05216 | 0.87178860 |
50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.85234912 |
51 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.84784711 |
52 | Allograft rejection_Homo sapiens_hsa05330 | 0.83932009 |
53 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.82570345 |
54 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.79309037 |
55 | Measles_Homo sapiens_hsa05162 | 0.78901121 |
56 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.78432173 |
57 | Shigellosis_Homo sapiens_hsa05131 | 0.77662065 |
58 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.77397397 |
59 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.76504648 |
60 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.75974402 |
61 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.75908460 |
62 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.74375932 |
63 | Viral myocarditis_Homo sapiens_hsa05416 | 0.74213596 |
64 | Protein export_Homo sapiens_hsa03060 | 0.73649013 |
65 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.72931709 |
66 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71334316 |
67 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.70440264 |
68 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.68541757 |
69 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.68289639 |
70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.68121651 |
71 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.67491512 |
72 | Hepatitis B_Homo sapiens_hsa05161 | 0.67441125 |
73 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.66949071 |
74 | Alcoholism_Homo sapiens_hsa05034 | 0.66729806 |
75 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.66422259 |
76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.66075327 |
77 | Apoptosis_Homo sapiens_hsa04210 | 0.62244540 |
78 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.61792799 |
79 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.61046359 |
80 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.60440905 |
81 | Huntingtons disease_Homo sapiens_hsa05016 | 0.59425984 |
82 | Adherens junction_Homo sapiens_hsa04520 | 0.58672265 |
83 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.56459438 |
84 | * AMPK signaling pathway_Homo sapiens_hsa04152 | 0.54240843 |
85 | Influenza A_Homo sapiens_hsa05164 | 0.53842962 |
86 | Leishmaniasis_Homo sapiens_hsa05140 | 0.53795711 |
87 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.52730405 |
88 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.50083197 |
89 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.49682454 |
90 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.49485404 |
91 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.48184242 |
92 | Asthma_Homo sapiens_hsa05310 | 0.47910149 |
93 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.47324633 |
94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.46498417 |
95 | Taste transduction_Homo sapiens_hsa04742 | 0.46340397 |
96 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46276148 |
97 | Pathways in cancer_Homo sapiens_hsa05200 | 0.45812824 |
98 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44405844 |
99 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.42270177 |
100 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.42069025 |
101 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41400528 |
102 | Bladder cancer_Homo sapiens_hsa05219 | 0.40051838 |
103 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.40047018 |
104 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39926171 |
105 | Prostate cancer_Homo sapiens_hsa05215 | 0.39275722 |
106 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.38685177 |
107 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.38560352 |
108 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37349275 |
109 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.36406610 |
110 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.35238253 |
111 | Parkinsons disease_Homo sapiens_hsa05012 | 0.34993536 |
112 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.34384051 |
113 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.34322452 |
114 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.34182683 |
115 | Salmonella infection_Homo sapiens_hsa05132 | 0.34149543 |
116 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33737333 |
117 | Phototransduction_Homo sapiens_hsa04744 | 0.33375096 |
118 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.31168455 |
119 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.30724560 |
120 | Metabolic pathways_Homo sapiens_hsa01100 | 0.30536657 |
121 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.30396175 |
122 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.29626022 |
123 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.29244273 |
124 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.28310372 |
125 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.26861473 |
126 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.26738067 |
127 | Melanoma_Homo sapiens_hsa05218 | 0.26717669 |
128 | Glioma_Homo sapiens_hsa05214 | 0.26589737 |
129 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26362306 |
130 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.26156955 |
131 | Prion diseases_Homo sapiens_hsa05020 | 0.26004966 |
132 | Endometrial cancer_Homo sapiens_hsa05213 | 0.25941424 |
133 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.25563647 |
134 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.25076383 |
135 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.24794342 |
136 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.23951438 |
137 | Malaria_Homo sapiens_hsa05144 | 0.23676934 |
138 | Melanogenesis_Homo sapiens_hsa04916 | 0.23515790 |
139 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.23441845 |
140 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.23185920 |
141 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.22395126 |
142 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.22219028 |
143 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.22023980 |
144 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.21367071 |
145 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.21017900 |
146 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.20456493 |
147 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.18527427 |