ELF3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.65195315
2interferon-gamma secretion (GO:0072643)8.19991576
3cilium or flagellum-dependent cell motility (GO:0001539)7.77605812
4intestinal epithelial cell development (GO:0060576)7.55045812
5motile cilium assembly (GO:0044458)6.66719142
6cilium movement (GO:0003341)6.58495176
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.71511432
8bundle of His cell to Purkinje myocyte communication (GO:0086069)5.47576706
9diterpenoid biosynthetic process (GO:0016102)5.39241557
10epithelial cilium movement (GO:0003351)5.37792449
11ethanol metabolic process (GO:0006067)5.28492030
12calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.86801398
13maintenance of gastrointestinal epithelium (GO:0030277)4.76553018
14axoneme assembly (GO:0035082)4.63378319
15ethanol oxidation (GO:0006069)4.60393342
16intestinal absorption (GO:0050892)4.50287565
17hepatocyte apoptotic process (GO:0097284)4.43732845
18regulation of cell-cell adhesion mediated by cadherin (GO:2000047)4.36001515
19lung epithelium development (GO:0060428)4.15844386
20regulation of water loss via skin (GO:0033561)4.02536518
21folic acid metabolic process (GO:0046655)3.98068675
22UDP-N-acetylglucosamine metabolic process (GO:0006047)3.97693420
23folic acid transport (GO:0015884)3.93258421
24trophectodermal cell differentiation (GO:0001829)3.89152406
25nucleotide-sugar biosynthetic process (GO:0009226)3.87325967
26tight junction assembly (GO:0070830)3.87002026
27GDP-mannose metabolic process (GO:0019673)3.80846090
28hemidesmosome assembly (GO:0031581)3.78422291
29epoxygenase P450 pathway (GO:0019373)3.69857192
30negative regulation of humoral immune response (GO:0002921)3.66469306
31desmosome organization (GO:0002934)3.66312689
32oligosaccharide biosynthetic process (GO:0009312)3.64527589
33cell differentiation involved in embryonic placenta development (GO:0060706)3.59577498
34terpenoid biosynthetic process (GO:0016114)3.58390969
35epithelial structure maintenance (GO:0010669)3.57085330
36multicellular organismal water homeostasis (GO:0050891)3.56743261
37left/right pattern formation (GO:0060972)3.56723142
38primary alcohol metabolic process (GO:0034308)3.56054990
39modified amino acid transport (GO:0072337)3.55596943
40one-carbon compound transport (GO:0019755)3.52602169
41galactose catabolic process (GO:0019388)3.50939337
42xenobiotic catabolic process (GO:0042178)3.49860122
43negative regulation of keratinocyte proliferation (GO:0010839)3.42176766
44excretion (GO:0007588)3.41910624
45glutathione biosynthetic process (GO:0006750)3.41864241
46exogenous drug catabolic process (GO:0042738)3.40910535
47regulation of cardioblast differentiation (GO:0051890)3.38552026
48O-glycan processing (GO:0016266)3.35263722
49purine nucleobase biosynthetic process (GO:0009113)3.34912969
50retinoic acid metabolic process (GO:0042573)3.34858516
51intestinal cholesterol absorption (GO:0030299)3.34245580
52retinol metabolic process (GO:0042572)3.33537148
53establishment of apical/basal cell polarity (GO:0035089)3.32102226
54establishment of skin barrier (GO:0061436)3.31951614
55fructose metabolic process (GO:0006000)3.31508310
56formation of translation preinitiation complex (GO:0001731)3.30378863
57digestion (GO:0007586)3.28417318
58negative regulation of T cell differentiation in thymus (GO:0033085)3.28258124
59sulfate transmembrane transport (GO:1902358)3.26235501
60antimicrobial humoral response (GO:0019730)3.24861095
61cellular glucuronidation (GO:0052695)3.24306405
62sperm capacitation (GO:0048240)3.24151693
63sodium ion homeostasis (GO:0055078)3.23455822
64antibacterial humoral response (GO:0019731)3.22820196
65drug catabolic process (GO:0042737)3.22003315
66digestive system process (GO:0022600)3.19540165
67glutathione derivative biosynthetic process (GO:1901687)3.17788382
68glutathione derivative metabolic process (GO:1901685)3.17788382
69vitamin transmembrane transport (GO:0035461)3.17730349
70nonribosomal peptide biosynthetic process (GO:0019184)3.16005969
71phosphatidylserine acyl-chain remodeling (GO:0036150)3.15045824
72sphingomyelin metabolic process (GO:0006684)3.13291881
73phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.12402315
74keratinocyte development (GO:0003334)3.10679172
75negative regulation of epidermal cell differentiation (GO:0045605)3.10588808
76nucleobase biosynthetic process (GO:0046112)3.07911840
77positive regulation of Cdc42 GTPase activity (GO:0043089)3.07256215
78renal absorption (GO:0070293)3.06488853
79labyrinthine layer development (GO:0060711)3.05925863
80epithelial cell-cell adhesion (GO:0090136)3.01769342
81sulfate transport (GO:0008272)3.01303062
82pyrimidine-containing compound transmembrane transport (GO:0072531)2.98992178
83ventricular cardiac muscle cell action potential (GO:0086005)2.96906989
84columnar/cuboidal epithelial cell development (GO:0002066)2.96752696
85water homeostasis (GO:0030104)2.95461636
86protein O-linked glycosylation (GO:0006493)2.95304333
87regulation of guanylate cyclase activity (GO:0031282)2.94974286
88drug metabolic process (GO:0017144)2.94918994
89vitamin transport (GO:0051180)2.92655974
90branching involved in labyrinthine layer morphogenesis (GO:0060670)2.91454840
91negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.91111063
92regulation of cholesterol homeostasis (GO:2000188)2.90389961
93positive regulation of pseudopodium assembly (GO:0031274)2.86279699
94ribosome assembly (GO:0042255)2.85732092
95sulfur compound transport (GO:0072348)2.84936807
96ear development (GO:0043583)2.83919732
973-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.83617081
98purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.83617081
99regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.83204937
100phosphatidylserine metabolic process (GO:0006658)2.80579285
101galactose metabolic process (GO:0006012)2.80432929
102progesterone metabolic process (GO:0042448)2.79561410
103proline biosynthetic process (GO:0006561)2.79461433
104hormone catabolic process (GO:0042447)2.79395970
105left/right axis specification (GO:0070986)2.79138056
106regulation of interleukin-5 production (GO:0032674)2.79134338
107alditol phosphate metabolic process (GO:0052646)2.78137447
108surfactant homeostasis (GO:0043129)2.76281499
109daunorubicin metabolic process (GO:0044597)2.76098442
110polyketide metabolic process (GO:0030638)2.76098442
111doxorubicin metabolic process (GO:0044598)2.76098442
112regulation of chemokine secretion (GO:0090196)2.76032334
113cyclooxygenase pathway (GO:0019371)2.75295499
114angiotensin maturation (GO:0002003)2.75092298
115regulation of pseudopodium assembly (GO:0031272)2.72801855
116regulation of respiratory burst (GO:0060263)2.71895800
117bicarbonate transport (GO:0015701)2.70836118
118L-ascorbic acid metabolic process (GO:0019852)2.70329914
119regulation of keratinocyte differentiation (GO:0045616)2.70111527
120proteasome assembly (GO:0043248)2.70079908
121regulation of metalloenzyme activity (GO:0048552)2.69764314
122auditory receptor cell differentiation (GO:0042491)2.68964871
123regulation of cilium movement (GO:0003352)2.68879921
124protein autoprocessing (GO:0016540)2.68289487
125regulation of proton transport (GO:0010155)2.68183353
126mitotic metaphase plate congression (GO:0007080)2.67561748
127microtubule bundle formation (GO:0001578)2.67544253
128glucuronate metabolic process (GO:0019585)2.67059555
129uronic acid metabolic process (GO:0006063)2.67059555
130positive regulation of epidermal cell differentiation (GO:0045606)2.66991460
131positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.66978310
132regulation of keratinocyte proliferation (GO:0010837)2.66828013
133ribosomal large subunit biogenesis (GO:0042273)2.66565769
134regulation of bile acid biosynthetic process (GO:0070857)2.65112264
135regulation of viral release from host cell (GO:1902186)2.64284516
136glandular epithelial cell differentiation (GO:0002067)2.62959374
137regulation of cellular amino acid metabolic process (GO:0006521)2.62247022
138phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.61881170
139maturation of SSU-rRNA (GO:0030490)2.61471407
140copper ion transport (GO:0006825)2.61266956
141primary alcohol catabolic process (GO:0034310)2.61149881
142response to nitrosative stress (GO:0051409)2.61044725
143pyrimidine nucleoside salvage (GO:0043097)2.59445699
144pyrimidine-containing compound salvage (GO:0008655)2.59445699
145regulation of translation in response to stress (GO:0043555)2.59226218
146phosphatidylcholine biosynthetic process (GO:0006656)2.59183302
147lung secretory cell differentiation (GO:0061140)2.59144834
148glomerular epithelial cell development (GO:0072310)2.58612069
149establishment of monopolar cell polarity (GO:0061162)2.58569984
150establishment or maintenance of monopolar cell polarity (GO:0061339)2.58569984
151transcytosis (GO:0045056)2.58142516
152negative regulation of complement activation (GO:0045916)2.56955133
153regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)2.56377248
154endocrine process (GO:0050886)2.56377248
155regulation of systemic arterial blood pressure by hormone (GO:0001990)2.56377248
156sulfur amino acid catabolic process (GO:0000098)2.56201253
157peptide catabolic process (GO:0043171)2.55718419
158phenylpropanoid metabolic process (GO:0009698)2.55058303
159glutathione metabolic process (GO:0006749)2.54743576
160negative regulation of epidermis development (GO:0045683)2.54451182
161transepithelial transport (GO:0070633)2.52686818
162nucleoside diphosphate biosynthetic process (GO:0009133)2.52643167
163flavonoid metabolic process (GO:0009812)2.52222587
164N-acetylneuraminate metabolic process (GO:0006054)2.52182748
165nucleotide-sugar metabolic process (GO:0009225)2.51140358
166retinal metabolic process (GO:0042574)2.50988790
167rRNA modification (GO:0000154)2.48747294
168positive regulation of respiratory burst (GO:0060267)2.48607191
169bile acid and bile salt transport (GO:0015721)2.47380304

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.10719422
2* TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.06478648
3NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.70605110
4E2F7_22180533_ChIP-Seq_HELA_Human2.66709395
5* TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.66404755
6* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.65039961
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.61722823
8ESR1_20079471_ChIP-ChIP_T-47D_Human2.55315719
9* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.54539132
10AR_21909140_ChIP-Seq_LNCAP_Human2.51733698
11* CDX2_20551321_ChIP-Seq_CACO-2_Human2.50287552
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.49824836
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.26679566
14SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.22984354
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.22256207
16* KLF4_18358816_ChIP-ChIP_MESCs_Mouse2.17206144
17STAT3_1855785_ChIP-Seq_MESCs_Mouse2.16774715
18NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.12966285
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.11886426
20TCF3_18692474_ChIP-Seq_MEFs_Mouse2.09729647
21* GATA6_25053715_ChIP-Seq_YYC3_Human2.07847949
22* GATA4_25053715_ChIP-Seq_YYC3_Human2.07385385
23NANOG_18555785_ChIP-Seq_MESCs_Mouse2.07237332
24* FOXO3_23340844_ChIP-Seq_DLD1_Human2.06023307
25HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.05505740
26ZNF263_19887448_ChIP-Seq_K562_Human2.05284281
27RXR_22158963_ChIP-Seq_LIVER_Mouse2.01538019
28* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.00318359
29FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.99231170
30* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.98245218
31* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.96592946
32FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.89945134
33SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.88701664
34NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.87493184
35P63_26484246_Chip-Seq_KERATINOCYTES_Human1.84954930
36SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.83108249
37KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.82319094
38KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.82319094
39KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.82319094
40FOXM1_23109430_ChIP-Seq_U2OS_Human1.81980733
41* ESR1_21235772_ChIP-Seq_MCF-7_Human1.80698756
42ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.80569234
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.79126203
44LXR_22158963_ChIP-Seq_LIVER_Mouse1.75194419
45MYC_18358816_ChIP-ChIP_MESCs_Mouse1.72185673
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.71776819
47FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.70755474
48SRY_22984422_ChIP-ChIP_TESTIS_Rat1.67693287
49* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.66736920
50ATF3_27146783_Chip-Seq_COLON_Human1.66187947
51JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.65271347
52* AHR_22903824_ChIP-Seq_MCF-7_Human1.62585204
53* SOX2_20726797_ChIP-Seq_SW620_Human1.62453426
54AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.62077793
55ETS1_20019798_ChIP-Seq_JURKAT_Human1.60243060
56* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.59620343
57* ESR2_21235772_ChIP-Seq_MCF-7_Human1.58618670
58KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.58129423
59* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.56649382
60ESR1_15608294_ChIP-ChIP_MCF-7_Human1.56145076
61NELFA_20434984_ChIP-Seq_ESCs_Mouse1.54145649
62* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.52954115
63EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.52195757
64RARG_19884340_ChIP-ChIP_MEFs_Mouse1.49873760
65SOX2_18692474_ChIP-Seq_MEFs_Mouse1.49386132
66* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.48667319
67TRIM28_21343339_ChIP-Seq_HEK293_Human1.46741961
68NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.46437336
69LXR_22292898_ChIP-Seq_THP-1_Human1.45823715
70* RACK7_27058665_Chip-Seq_MCF-7_Human1.44311366
71NANOG_18692474_ChIP-Seq_MEFs_Mouse1.43146098
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42820144
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.41795532
74CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.41590262
75EST1_17652178_ChIP-ChIP_JURKAT_Human1.39891640
76TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.38124257
77NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.38077411
78TCF3_18692474_ChIP-Seq_MESCs_Mouse1.37318550
79CLOCK_20551151_ChIP-Seq_293T_Human1.36149217
80* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.35485868
81FOXA1_25552417_ChIP-Seq_VCAP_Human1.35252596
82EGR1_23403033_ChIP-Seq_LIVER_Mouse1.34961549
83DROSHA_22980978_ChIP-Seq_HELA_Human1.34824373
84SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.34762269
85GABP_17652178_ChIP-ChIP_JURKAT_Human1.33867014
86* CREB1_26743006_Chip-Seq_LNCaP_Human1.33488472
87YY1_21170310_ChIP-Seq_MESCs_Mouse1.33320499
88* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.33145533
89PPARA_22158963_ChIP-Seq_LIVER_Mouse1.31331758
90KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31156579
91FOXA2_19822575_ChIP-Seq_HepG2_Human1.30505558
92CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.27837045
93SMC4_20622854_ChIP-Seq_HELA_Human1.26820043
94POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24165671
95XRN2_22483619_ChIP-Seq_HELA_Human1.23839021
96SOX9_24532713_ChIP-Seq_HFSC_Mouse1.23475721
97* TP63_22573176_ChIP-Seq_HFKS_Human1.23145189
98PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.23106014
99CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.22446763
100* RUNX1_27514584_Chip-Seq_MCF-7_Human1.21991250
101ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.19617441
102* ARNT_22903824_ChIP-Seq_MCF-7_Human1.16861321
103SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.16769598
104SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.16769598
105PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16620728
106ELK1_22589737_ChIP-Seq_MCF10A_Human1.16500695
107CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.15616454
108IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.14638093
109SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11721007
110STAT1_20625510_ChIP-Seq_HELA_Human1.10503390
111NANOG_18692474_ChIP-Seq_MESCs_Mouse1.09882422
112* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.08317468
113* PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06977923
114CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06727090
115* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.05453949
116ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.05377977
117SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.05249883
118* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.04776567
119* GATA3_24758297_ChIP-Seq_MCF-7_Human1.03632771
120* CTCF_27219007_Chip-Seq_Bcells_Human1.03320473
121* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.03252887
122TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01115133
123FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.00764586
124P68_20966046_ChIP-Seq_HELA_Human1.00424419
125* KLF5_25053715_ChIP-Seq_YYC3_Human0.99859984
126SOX2_18692474_ChIP-Seq_MESCs_Mouse0.99733284
127TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99479428
128SOX17_20123909_ChIP-Seq_XEN_Mouse0.98588648
129KAP1_27257070_Chip-Seq_ESCs_Mouse0.98449235
130BCOR_27268052_Chip-Seq_Bcells_Human0.98372769
131EGR1_19374776_ChIP-ChIP_THP-1_Human0.98327790
132KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97661010
133POU5F1_16518401_ChIP-PET_MESCs_Mouse0.97263842
134CTNNB1_20460455_ChIP-Seq_HCT116_Human0.97099275
135E2F4_17652178_ChIP-ChIP_JURKAT_Human0.96630347
136CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96597855
137KDM5A_27292631_Chip-Seq_BREAST_Human0.96286098
138MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.95711524
139TP63_23658742_ChIP-Seq_EP156T_Human0.94399799
140NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.94287155
141* HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93620560
142BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.93513251
143IRF8_22096565_ChIP-ChIP_GC-B_Human0.93400791
144FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.92634964
145RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90864941
146HNF4A_19822575_ChIP-Seq_HepG2_Human0.88160313
147THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87923911
148TCF4_18268006_ChIP-ChIP_LS174T_Human0.85923272
149ELF5_23300383_ChIP-Seq_T47D_Human0.85471079
150PHF8_20622854_ChIP-Seq_HELA_Human0.83219168
151* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.83153773
152SA1_27219007_Chip-Seq_Bcells_Human0.82606466
153UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.81643496
154BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80684240
155GATA2_21666600_ChIP-Seq_HMVEC_Human0.78859753
156ELK3_25401928_ChIP-Seq_HUVEC_Human0.78151982
157SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.77510348
158CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.77487996
159SA1_27219007_Chip-Seq_ERYTHROID_Human0.77473154
160CEBPB_22108803_ChIP-Seq_LS180_Human0.77271823
161E2F1_20622854_ChIP-Seq_HELA_Human0.77111882

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle5.96786750
2MP0004264_abnormal_extraembryonic_tissu4.11885112
3MP0003693_abnormal_embryo_hatching3.97038433
4MP0000462_abnormal_digestive_system3.21826213
5MP0000537_abnormal_urethra_morphology3.12227992
6MP0010352_gastrointestinal_tract_polyps2.99056494
7MP0008004_abnormal_stomach_pH2.99007931
8MP0009840_abnormal_foam_cell2.94157299
9MP0005083_abnormal_biliary_tract2.89125464
10MP0009780_abnormal_chondrocyte_physiolo2.78659847
11MP0001666_abnormal_nutrient_absorption2.68292307
12MP0004957_abnormal_blastocyst_morpholog2.58174842
13MP0003806_abnormal_nucleotide_metabolis2.42352656
14MP0005377_hearing/vestibular/ear_phenot2.35219376
15MP0003878_abnormal_ear_physiology2.35219376
16MP0004019_abnormal_vitamin_homeostasis2.18647735
17MP0000490_abnormal_crypts_of2.10037614
18MP0010678_abnormal_skin_adnexa1.93817981
19MP0002796_impaired_skin_barrier1.90659844
20MP0003941_abnormal_skin_development1.86293245
21MP0003718_maternal_effect1.82966018
22MP0003111_abnormal_nucleus_morphology1.81872878
23MP0002098_abnormal_vibrissa_morphology1.81536714
24MP0003315_abnormal_perineum_morphology1.80774680
25MP0001873_stomach_inflammation1.77453865
26MP0002132_abnormal_respiratory_system1.74489823
27MP0003183_abnormal_peptide_metabolism1.73052549
28* MP0003866_abnormal_defecation1.72576863
29MP0002876_abnormal_thyroid_physiology1.70312622
30MP0002277_abnormal_respiratory_mucosa1.69371883
31MP0005360_urolithiasis1.66786914
32* MP0000477_abnormal_intestine_morphology1.59870246
33MP0001756_abnormal_urination1.57306201
34MP0005381_digestive/alimentary_phenotyp1.56406288
35MP0008875_abnormal_xenobiotic_pharmacok1.56294172
36MP0001664_abnormal_digestion1.55469880
37MP0001663_abnormal_digestive_system1.55075131
38MP0009643_abnormal_urine_homeostasis1.50803908
39MP0000613_abnormal_salivary_gland1.49033600
40MP0010155_abnormal_intestine_physiology1.45818676
41MP0002909_abnormal_adrenal_gland1.42855785
42MP0005670_abnormal_white_adipose1.41800767
43MP0001849_ear_inflammation1.41682001
44MP0005085_abnormal_gallbladder_physiolo1.41188056
45MP0003453_abnormal_keratinocyte_physiol1.40271519
46MP0004885_abnormal_endolymph1.35899850
47MP0002254_reproductive_system_inflammat1.32818871
48MP0010030_abnormal_orbit_morphology1.29883163
49MP0000383_abnormal_hair_follicle1.29334002
50MP0003119_abnormal_digestive_system1.26690362
51MP0003186_abnormal_redox_activity1.26511252
52MP0003300_gastrointestinal_ulcer1.22419095
53MP0004782_abnormal_surfactant_physiolog1.21382060
54MP0001216_abnormal_epidermal_layer1.20966417
55MP0002138_abnormal_hepatobiliary_system1.20866174
56MP0001485_abnormal_pinna_reflex1.20660154
57MP0003077_abnormal_cell_cycle1.20464966
58MP0004043_abnormal_pH_regulation1.20311118
59MP0003566_abnormal_cell_adhesion1.19178050
60MP0001730_embryonic_growth_arrest1.19170051
61MP0000678_abnormal_parathyroid_gland1.18799753
62MP0005501_abnormal_skin_physiology1.18065702
63MP0003705_abnormal_hypodermis_morpholog1.17682635
64MP0000470_abnormal_stomach_morphology1.15511718
65MP0005409_darkened_coat_color1.14978813
66MP0005367_renal/urinary_system_phenotyp1.14663220
67MP0000516_abnormal_urinary_system1.14663220
68MP0005166_decreased_susceptibility_to1.13700550
69MP0000762_abnormal_tongue_morphology1.11922977
70MP0008872_abnormal_physiological_respon1.07659906
71MP0004858_abnormal_nervous_system1.06695439
72MP0002168_other_aberrant_phenotype1.03251409
73MP0003868_abnormal_feces_composition1.02789124
74MP0005023_abnormal_wound_healing1.02730555
75MP0002060_abnormal_skin_morphology1.01743248
76MP0003252_abnormal_bile_duct1.00567234
77MP0005408_hypopigmentation1.00465402
78MP0005165_increased_susceptibility_to0.97599624
79MP0008932_abnormal_embryonic_tissue0.97550237
80MP0001765_abnormal_ion_homeostasis0.95993723
81MP0008789_abnormal_olfactory_epithelium0.95315135
82MP0002086_abnormal_extraembryonic_tissu0.93171853
83MP0005395_other_phenotype0.92227404
84MP0004947_skin_inflammation0.92025851
85MP0003045_fibrosis0.91854075
86MP0009053_abnormal_anal_canal0.91408611
87MP0001881_abnormal_mammary_gland0.91056964
88MP0005380_embryogenesis_phenotype0.90813392
89MP0001672_abnormal_embryogenesis/_devel0.90813392
90MP0002136_abnormal_kidney_physiology0.88776862
91MP0000377_abnormal_hair_follicle0.88619686
92MP0009379_abnormal_foot_pigmentation0.88601765
93MP0002653_abnormal_ependyma_morphology0.86221004
94MP0005076_abnormal_cell_differentiation0.85487804
95MP0002249_abnormal_larynx_morphology0.85430818
96MP0000467_abnormal_esophagus_morphology0.84930584
97MP0002118_abnormal_lipid_homeostasis0.83930736
98MP0000627_abnormal_mammary_gland0.83231933
99MP0002139_abnormal_hepatobiliary_system0.81909572
100MP0000350_abnormal_cell_proliferation0.81759655
101MP0000465_gastrointestinal_hemorrhage0.81727195
102MP0003879_abnormal_hair_cell0.81690622
103MP0000681_abnormal_thyroid_gland0.80766346
104MP0002896_abnormal_bone_mineralization0.79900213
105MP0003283_abnormal_digestive_organ0.79475496
106MP0010771_integument_phenotype0.79313064
107MP0005636_abnormal_mineral_homeostasis0.79275814
108MP0006054_spinal_hemorrhage0.76642381
109MP0000566_synostosis0.76156191
110MP0005394_taste/olfaction_phenotype0.75923746
111MP0005499_abnormal_olfactory_system0.75923746
112MP0005332_abnormal_amino_acid0.75160291
113MP0005319_abnormal_enzyme/_coenzyme0.74650217
114MP0002166_altered_tumor_susceptibility0.74112295
115MP0003786_premature_aging0.74051193
116MP0003984_embryonic_growth_retardation0.73470784
117MP0000538_abnormal_urinary_bladder0.73333301
118MP0000013_abnormal_adipose_tissue0.72952273
119MP0002088_abnormal_embryonic_growth/wei0.72853450
120MP0002085_abnormal_embryonic_tissue0.70983463
121MP0010386_abnormal_urinary_bladder0.70521370
122MP0010329_abnormal_lipoprotein_level0.69610649
123MP0010094_abnormal_chromosome_stability0.69499886
124MP0000609_abnormal_liver_physiology0.69396977
125MP0005666_abnormal_adipose_tissue0.69218084
126MP0003638_abnormal_response/metabolism_0.68398486
127MP0001502_abnormal_circadian_rhythm0.68157347
128MP0001346_abnormal_lacrimal_gland0.67738757
129MP0005365_abnormal_bile_salt0.67446799
130MP0001697_abnormal_embryo_size0.67408382
131MP0003191_abnormal_cellular_cholesterol0.64409670
132MP0005310_abnormal_salivary_gland0.64226731
133MP0002877_abnormal_melanocyte_morpholog0.63698036
134MP0005220_abnormal_exocrine_pancreas0.63311152
135* MP0002080_prenatal_lethality0.63243718
136MP0004133_heterotaxia0.61871563
137MP0002111_abnormal_tail_morphology0.61708781
138MP0003936_abnormal_reproductive_system0.60675916

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.93585371
2Abnormal respiratory epithelium morphology (HP:0012253)7.60018576
3Abnormal respiratory motile cilium morphology (HP:0005938)7.60018576
4Abnormal respiratory motile cilium physiology (HP:0012261)7.48833849
5Absent/shortened dynein arms (HP:0200106)7.33535279
6Dynein arm defect of respiratory motile cilia (HP:0012255)7.33535279
7Abnormal ciliary motility (HP:0012262)7.14822667
8Rhinitis (HP:0012384)7.11840235
9Ileus (HP:0002595)6.74827521
10Bronchiectasis (HP:0002110)5.69056751
11Hyperactive renin-angiotensin system (HP:0000841)5.25626077
12Nasal polyposis (HP:0100582)5.24519663
13Abnormality of chloride homeostasis (HP:0011422)5.15019320
14Abnormality of cochlea (HP:0000375)4.98932781
15Right ventricular cardiomyopathy (HP:0011663)4.81232170
16Abnormality of the nasal mucosa (HP:0000433)4.57472569
17Renal salt wasting (HP:0000127)4.02971701
18Pili torti (HP:0003777)3.78769808
19Bronchitis (HP:0012387)3.77831606
20Hyperaldosteronism (HP:0000859)3.73676336
21Metabolic alkalosis (HP:0200114)3.48510770
22Onycholysis (HP:0001806)3.41910387
23Hypokalemic alkalosis (HP:0001949)3.37140185
24Abnormal biliary tract morphology (HP:0012440)3.35944757
25Micronodular cirrhosis (HP:0001413)3.33266728
26Pustule (HP:0200039)3.32914141
27Rectal prolapse (HP:0002035)3.31333889
28Morphological abnormality of the inner ear (HP:0011390)3.21735511
29Ventricular fibrillation (HP:0001663)3.17561588
30Chronic sinusitis (HP:0011109)3.12286697
31Fragile nails (HP:0001808)3.04958096
32Hyponatremia (HP:0002902)3.03177164
33Infertility (HP:0000789)2.99586668
34Abdominal distention (HP:0003270)2.99420219
35Recurrent otitis media (HP:0000403)2.95642695
36Conjugated hyperbilirubinemia (HP:0002908)2.92603058
37Recurrent sinusitis (HP:0011108)2.90886908
38Biliary tract neoplasm (HP:0100574)2.90094047
39Abnormality of small intestinal villus morphology (HP:0011472)2.89897793
40Villous atrophy (HP:0011473)2.89897793
41Cheilitis (HP:0100825)2.88645641
42Breast hypoplasia (HP:0003187)2.82876262
43Woolly hair (HP:0002224)2.80597476
44Trismus (HP:0000211)2.79387737
45Hyperkalemia (HP:0002153)2.78792706
46Lip pit (HP:0100267)2.78002505
47Alkalosis (HP:0001948)2.76963459
48Chronic bronchitis (HP:0004469)2.74134804
49Milia (HP:0001056)2.70714285
50Decreased circulating renin level (HP:0003351)2.68275411
51Fat malabsorption (HP:0002630)2.61989835
52Esophageal varix (HP:0002040)2.61578948
53Abnormality of the distal phalanges of the toes (HP:0010182)2.56624809
54Male infertility (HP:0003251)2.50434028
55Chronic otitis media (HP:0000389)2.50063694
56Abnormal pancreas size (HP:0012094)2.46240997
57Dehydration (HP:0001944)2.45717124
58Tubulointerstitial nephritis (HP:0001970)2.45640957
59Abnormality of proline metabolism (HP:0010907)2.44976748
60Hydroxyprolinuria (HP:0003080)2.44976748
61Rough bone trabeculation (HP:0100670)2.43795026
62Malnutrition (HP:0004395)2.42392993
63Gastrointestinal dysmotility (HP:0002579)2.39715771
64Congenital sensorineural hearing impairment (HP:0008527)2.38088298
65Abnormality of renin-angiotensin system (HP:0000847)2.35492707
66Alopecia of scalp (HP:0002293)2.33600409
67Flat acetabular roof (HP:0003180)2.33087212
68Abnormality of sodium homeostasis (HP:0010931)2.28794963
69Atelectasis (HP:0100750)2.28033860
70Microretrognathia (HP:0000308)2.26370787
71Stenosis of the external auditory canal (HP:0000402)2.21471795
72Death in infancy (HP:0001522)2.20558582
73Hypokalemia (HP:0002900)2.20174305
74Abnormal tarsal ossification (HP:0008369)2.18080637
75Aplasia/hypoplasia of the uterus (HP:0008684)2.17869775
76Cardiovascular calcification (HP:0011915)2.17858474
77Hypoplasia of the uterus (HP:0000013)2.16698044
78Atrophic scars (HP:0001075)2.14035902
79Popliteal pterygium (HP:0009756)2.13926045
80Proximal tubulopathy (HP:0000114)2.13031144
81Plantar hyperkeratosis (HP:0007556)2.12878055
82Abnormality of urine glucose concentration (HP:0011016)2.12182627
83Glycosuria (HP:0003076)2.12182627
84Steatorrhea (HP:0002570)2.12165950
85Abnormal hemoglobin (HP:0011902)2.11394466
86Gout (HP:0001997)2.10756443
87Focal segmental glomerulosclerosis (HP:0000097)2.10036194
88Abnormality of permanent molar morphology (HP:0011071)2.09541655
89Abnormality of the dental root (HP:0006486)2.09541655
90Taurodontia (HP:0000679)2.09541655
91Megaloblastic anemia (HP:0001889)2.08880894
92Occipital encephalocele (HP:0002085)2.08547310
93Hyperuricemia (HP:0002149)2.08352292
94Increased purine levels (HP:0004368)2.08352292
95Tubular atrophy (HP:0000092)2.08123651
96Abnormality of the 1st metacarpal (HP:0010009)2.06660731
97Ureteral duplication (HP:0000073)2.06586590
98Aplasia/hypoplasia of the humerus (HP:0006507)2.06194428
99Curly hair (HP:0002212)2.04284533
100Carpal bone hypoplasia (HP:0001498)2.03452380
101Septate vagina (HP:0001153)2.03283726
102Abnormality of monocarboxylic acid metabolism (HP:0010996)2.02228252
103Hyperparathyroidism (HP:0000843)2.00717414
104Palpitations (HP:0001962)1.99084963
105Intrahepatic cholestasis (HP:0001406)1.97713673
106Hemorrhage of the eye (HP:0011885)1.97550696
107Multiple enchondromatosis (HP:0005701)1.97116641
108Hyperglycinuria (HP:0003108)1.94948102
109Bell-shaped thorax (HP:0001591)1.94703702
110Aplasia/Hypoplasia of the sacrum (HP:0008517)1.93362622
111Abnormality of molar morphology (HP:0011070)1.93241569
112Abnormality of molar (HP:0011077)1.93241569
113Hypotension (HP:0002615)1.92318521
114Spinal muscular atrophy (HP:0007269)1.92273212
115Abnormal blistering of the skin (HP:0008066)1.91820816
116Uterine neoplasm (HP:0010784)1.91545794
117Cystic liver disease (HP:0006706)1.91385534
118Adrenal overactivity (HP:0002717)1.90665319
119Abnormality of the dental pulp (HP:0006479)1.90130129
120Stridor (HP:0010307)1.88989943
121Abnormal trabecular bone morphology (HP:0100671)1.87200258
122Congenital, generalized hypertrichosis (HP:0004540)1.87106859
123Sparse eyelashes (HP:0000653)1.86437350
124Abnormality of the anterior horn cell (HP:0006802)1.86435765
125Degeneration of anterior horn cells (HP:0002398)1.86435765
126Abnormal hair laboratory examination (HP:0003328)1.85796970
127Hyperphosphatemia (HP:0002905)1.84564444
128Amelogenesis imperfecta (HP:0000705)1.84219362
129Tongue fasciculations (HP:0001308)1.83818362
130Congenital ichthyosiform erythroderma (HP:0007431)1.82039648
131Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81716892
132Abnormality of the umbilical cord (HP:0010881)1.81437569
133Abnormality of glutamine family amino acid metabolism (HP:0010902)1.80530762
134Short humerus (HP:0005792)1.80504220
135Syncope (HP:0001279)1.80085654
136Stomach cancer (HP:0012126)1.80045775
137Nail dystrophy (HP:0008404)1.79591125
138Abnormalities of placenta or umbilical cord (HP:0001194)1.79499944
139Cone-rod dystrophy (HP:0000548)1.78853947
140Pterygium (HP:0001059)1.78472240
141Widely patent fontanelles and sutures (HP:0004492)1.78451549
142Distal lower limb muscle weakness (HP:0009053)1.78190992
143Glomerulosclerosis (HP:0000096)1.76857354
144Malignant gastrointestinal tract tumors (HP:0006749)1.75978974
145Gastrointestinal carcinoma (HP:0002672)1.75978974
146Osteomalacia (HP:0002749)1.75407458
147Flattened epiphyses (HP:0003071)1.74426121
148Vascular calcification (HP:0004934)1.73751286
149Renal tubular acidosis (HP:0001947)1.73316716
150True hermaphroditism (HP:0010459)1.66224196
151Abnormality of renal excretion (HP:0011036)1.64788468
152Bifid scrotum (HP:0000048)1.64355727
153Abnormality of vitamin metabolism (HP:0100508)1.62085345
154Spinal cord compression (HP:0002176)1.59658115
155Diaphragmatic weakness (HP:0009113)1.59227788
156Bronchomalacia (HP:0002780)1.58375871
157Recurrent bronchitis (HP:0002837)1.57242244
158Interstitial pulmonary disease (HP:0006530)1.56132728
159Hypoplasia of dental enamel (HP:0006297)1.54823288
160Abnormality of potassium homeostasis (HP:0011042)1.53291691
161Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.50512102
162Abnormal glucose tolerance (HP:0001952)1.50018995
163Upper limb amyotrophy (HP:0009129)1.49993249
164Distal upper limb amyotrophy (HP:0007149)1.49993249
165Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.49237121
166Short nail (HP:0001799)1.47514439

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA28.31449863
2LMTK25.56935745
3MST43.11767137
4FRK2.79380412
5WEE12.68473181
6BUB12.64609489
7NME12.62586401
8MAP2K22.62577812
9MST1R2.51399466
10RPS6KB22.49616946
11TTK2.29787637
12ERN12.15042898
13PRKG22.12662941
14STK392.10096804
15AKT31.85748630
16MAP3K31.76193336
17EIF2AK11.59555958
18PRKCI1.56570176
19NEK11.51235702
20SMG11.47013296
21STK38L1.44814602
22TESK11.43542123
23PBK1.38186285
24TSSK61.35032813
25EPHB21.33227828
26PAK41.31035516
27OXSR11.28443710
28FGFR41.28219726
29EPHB11.27349304
30ACVR1B1.24461062
31MAP3K21.23646818
32SIK11.22276207
33MAP3K121.21966634
34MET1.19926969
35ZAK1.19398796
36MAP3K111.16814462
37EPHA31.16274353
38FER1.15922439
39STK161.11051894
40EEF2K1.09749695
41TAOK11.08646296
42IRAK31.08272174
43AURKB1.07894769
44MAP3K81.07649846
45MAPK150.98364797
46MAP2K60.95216665
47PTK20.94415684
48STK100.94256314
49MAP2K10.92808830
50NUAK10.90648770
51PNCK0.89999296
52NEK60.87848850
53RIPK10.87821528
54PLK10.86967756
55PDK20.85253031
56TBK10.75945187
57WNK40.75009842
58PTK60.73883066
59SCYL20.72267034
60NEK20.71562462
61STK380.69117741
62FGFR30.68764098
63LATS10.67818945
64AURKA0.67489433
65PLK40.66407323
66MAP3K70.65592877
67BRSK20.65389863
68MYLK0.64433407
69EIF2AK30.63916878
70ERBB20.63350106
71PASK0.62464824
72GRK60.61360510
73MUSK0.61011819
74CHUK0.60905656
75TESK20.60519076
76CDC42BPA0.59908407
77PDK40.59739737
78PDK30.59739737
79NLK0.58365965
80TAOK20.58198760
81PRKAA20.57700377
82PKN20.57112589
83TLK10.56437278
84SRPK10.51414112
85PDPK10.50621667
86PIM20.49321179
87MAPKAPK30.48867491
88IRAK10.48502157
89PLK30.48380958
90TRPM70.47946103
91CHEK20.47921475
92ICK0.47719565
93PIK3CA0.47409061
94ARAF0.47216859
95HIPK20.46402951
96CAMK2D0.45217469
97DMPK0.44887263
98BCR0.44026214
99CDK70.43386043
100MELK0.43229654
101BRAF0.42860798
102RPS6KA20.42518399
103VRK10.42185675
104LRRK20.40436953
105DYRK30.39881453
106CAMK2G0.38876116
107STK30.37748901
108CAMK2B0.37747050
109MARK20.37699118
110RPS6KA40.35692071
111TRIB30.35367664
112GRK10.34808172
113CSNK1E0.33646486
114MAP3K60.31793678
115MAPK110.31253322
116IKBKB0.29842849
117MAP3K90.29617042
118* PAK10.29412846
119MAPKAPK20.29401937
120ERBB40.28872762
121SIK30.27437777
122PRKCD0.27219368
123MAP3K140.26918387
124MAP3K10.26513491
125TYK20.26323081
126MTOR0.26184722
127CSNK2A10.26030472
128STK240.25833447
129IKBKE0.25362479
130ABL20.25267011
131SRC0.25125892
132MATK0.24755814
133DDR20.24536289
134PRKD20.24163771
135NME20.23496207
136CSK0.23413772
137ALK0.22225713
138BMX0.21855651
139STK40.21264997
140ZAP700.20658740
141CSNK1A10.19717773
142PRKCA0.19612832
143CHEK10.18984638
144PDGFRB0.18947838
145IGF1R0.18000291
146LIMK10.17691400
147ROCK10.17470496
148CDK40.17123085
149AKT20.16930337

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.30130205
2Sulfur metabolism_Homo sapiens_hsa009203.18646153
3Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.95267877
4Mineral absorption_Homo sapiens_hsa049782.81631854
5Fat digestion and absorption_Homo sapiens_hsa049752.79921423
6Proteasome_Homo sapiens_hsa030502.74627744
7Fructose and mannose metabolism_Homo sapiens_hsa000512.74171576
8Glutathione metabolism_Homo sapiens_hsa004802.48051064
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.46423844
10Galactose metabolism_Homo sapiens_hsa000522.45668326
11Folate biosynthesis_Homo sapiens_hsa007902.27129528
12Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.22942092
13Tyrosine metabolism_Homo sapiens_hsa003502.05415537
14Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.93516625
15Arginine biosynthesis_Homo sapiens_hsa002201.91734431
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.85081397
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.83079909
18Vitamin digestion and absorption_Homo sapiens_hsa049771.75737815
19Tight junction_Homo sapiens_hsa045301.72344524
20Ribosome_Homo sapiens_hsa030101.71862357
21Pentose phosphate pathway_Homo sapiens_hsa000301.70475860
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.66047157
23Histidine metabolism_Homo sapiens_hsa003401.66022932
24Renin-angiotensin system_Homo sapiens_hsa046141.63135954
25Arachidonic acid metabolism_Homo sapiens_hsa005901.53964748
26Chemical carcinogenesis_Homo sapiens_hsa052041.51143191
27Linoleic acid metabolism_Homo sapiens_hsa005911.50259010
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47491462
29RNA polymerase_Homo sapiens_hsa030201.43368434
30Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.39989438
31Sulfur relay system_Homo sapiens_hsa041221.39603428
32Drug metabolism - other enzymes_Homo sapiens_hsa009831.34103571
33Pyrimidine metabolism_Homo sapiens_hsa002401.30090609
34Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.29059067
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.26284468
36RNA transport_Homo sapiens_hsa030131.24312465
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.21325103
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.21220296
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.19291694
40Regulation of autophagy_Homo sapiens_hsa041401.17837418
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.17157953
42DNA replication_Homo sapiens_hsa030301.15040811
43Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.13077169
44Nitrogen metabolism_Homo sapiens_hsa009101.12750646
45Mismatch repair_Homo sapiens_hsa034301.12073342
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.06401202
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.02553554
48Carbon metabolism_Homo sapiens_hsa012001.02544110
49Cyanoamino acid metabolism_Homo sapiens_hsa004601.02324285
50Arginine and proline metabolism_Homo sapiens_hsa003301.02211215
51Glycerolipid metabolism_Homo sapiens_hsa005611.01595984
52Oxidative phosphorylation_Homo sapiens_hsa001901.01152599
53PPAR signaling pathway_Homo sapiens_hsa033201.00755021
54Carbohydrate digestion and absorption_Homo sapiens_hsa049730.98631307
55Starch and sucrose metabolism_Homo sapiens_hsa005000.97419621
56Glycerophospholipid metabolism_Homo sapiens_hsa005640.96649971
57Retinol metabolism_Homo sapiens_hsa008300.96486636
58beta-Alanine metabolism_Homo sapiens_hsa004100.95822337
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93268545
60Selenocompound metabolism_Homo sapiens_hsa004500.92370121
61Vibrio cholerae infection_Homo sapiens_hsa051100.92145080
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.92111987
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91470507
64Other glycan degradation_Homo sapiens_hsa005110.86529770
65Homologous recombination_Homo sapiens_hsa034400.83888883
66Base excision repair_Homo sapiens_hsa034100.78183053
67Huntingtons disease_Homo sapiens_hsa050160.75335750
68Spliceosome_Homo sapiens_hsa030400.73822586
69Protein digestion and absorption_Homo sapiens_hsa049740.72087837
70Adherens junction_Homo sapiens_hsa045200.71322843
71Parkinsons disease_Homo sapiens_hsa050120.71156547
72Cysteine and methionine metabolism_Homo sapiens_hsa002700.70258591
73Sphingolipid metabolism_Homo sapiens_hsa006000.68873075
74Bile secretion_Homo sapiens_hsa049760.68367671
75Complement and coagulation cascades_Homo sapiens_hsa046100.68354080
76Leukocyte transendothelial migration_Homo sapiens_hsa046700.67457779
77Pancreatic secretion_Homo sapiens_hsa049720.67043190
78One carbon pool by folate_Homo sapiens_hsa006700.67009827
79Metabolic pathways_Homo sapiens_hsa011000.65956905
80Fatty acid degradation_Homo sapiens_hsa000710.65941181
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.65893306
82Biosynthesis of amino acids_Homo sapiens_hsa012300.64987219
83Purine metabolism_Homo sapiens_hsa002300.64818846
84Peroxisome_Homo sapiens_hsa041460.64796723
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64382704
86Vitamin B6 metabolism_Homo sapiens_hsa007500.62724665
87p53 signaling pathway_Homo sapiens_hsa041150.62145273
88Cell cycle_Homo sapiens_hsa041100.60623241
89Hippo signaling pathway_Homo sapiens_hsa043900.59928341
90Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59115818
91Thyroid cancer_Homo sapiens_hsa052160.58549269
92Insulin resistance_Homo sapiens_hsa049310.55403067
93Tryptophan metabolism_Homo sapiens_hsa003800.54347710
94Bladder cancer_Homo sapiens_hsa052190.51992284
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51075408
96Circadian rhythm_Homo sapiens_hsa047100.49868630
97Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45368646
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.44661237
99Caffeine metabolism_Homo sapiens_hsa002320.43866410
100Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.43834063
101Hepatitis C_Homo sapiens_hsa051600.43771174
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.43074577
103Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.42427478
104Notch signaling pathway_Homo sapiens_hsa043300.40275900
105Phenylalanine metabolism_Homo sapiens_hsa003600.39618403
106Ether lipid metabolism_Homo sapiens_hsa005650.39580168
107Nucleotide excision repair_Homo sapiens_hsa034200.39217333
108Salivary secretion_Homo sapiens_hsa049700.38561031
109Alzheimers disease_Homo sapiens_hsa050100.37074842
110Steroid hormone biosynthesis_Homo sapiens_hsa001400.36150474
111Lysosome_Homo sapiens_hsa041420.35674922
112Glycosaminoglycan degradation_Homo sapiens_hsa005310.34975969
113Thyroid hormone synthesis_Homo sapiens_hsa049180.34293994
114Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.33320229
115Pyruvate metabolism_Homo sapiens_hsa006200.33032308
116Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32392538
117Legionellosis_Homo sapiens_hsa051340.31364877
118Choline metabolism in cancer_Homo sapiens_hsa052310.31218093
119Collecting duct acid secretion_Homo sapiens_hsa049660.30645530
120Butanoate metabolism_Homo sapiens_hsa006500.30149292
121Ovarian steroidogenesis_Homo sapiens_hsa049130.28783583
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28264869
123N-Glycan biosynthesis_Homo sapiens_hsa005100.26568240
124ABC transporters_Homo sapiens_hsa020100.25387470
125Small cell lung cancer_Homo sapiens_hsa052220.25381584
126Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.24050984
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.19420573
128TNF signaling pathway_Homo sapiens_hsa046680.18561292
129Amoebiasis_Homo sapiens_hsa051460.16881682
130Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.13075791
131Fatty acid biosynthesis_Homo sapiens_hsa000610.12055097
132Fatty acid metabolism_Homo sapiens_hsa012120.10029154
133Influenza A_Homo sapiens_hsa051640.09911214
134Pertussis_Homo sapiens_hsa051330.05969945
135Endocytosis_Homo sapiens_hsa041440.05872819
136Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.05797253
137Adipocytokine signaling pathway_Homo sapiens_hsa049200.05358768

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