ELOF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.59250705
2chaperone-mediated protein transport (GO:0072321)5.01265161
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.83329189
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.43011842
5ATP synthesis coupled proton transport (GO:0015986)4.43011842
6protein targeting to mitochondrion (GO:0006626)4.41879847
7establishment of protein localization to mitochondrial membrane (GO:0090151)4.40162558
8regulation of mitochondrial translation (GO:0070129)4.18622946
9establishment of protein localization to mitochondrion (GO:0072655)4.15828918
10protein localization to mitochondrion (GO:0070585)3.97390755
11proteasome assembly (GO:0043248)3.93991363
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.92027067
13establishment of viral latency (GO:0019043)3.89596736
14establishment of integrated proviral latency (GO:0075713)3.85052903
15pseudouridine synthesis (GO:0001522)3.81743478
16purine nucleobase biosynthetic process (GO:0009113)3.80118894
17DNA strand elongation involved in DNA replication (GO:0006271)3.79007417
18respiratory electron transport chain (GO:0022904)3.78442403
19mitotic metaphase plate congression (GO:0007080)3.77881351
20axonemal dynein complex assembly (GO:0070286)3.77578807
21binding of sperm to zona pellucida (GO:0007339)3.73713179
22telomere maintenance via semi-conservative replication (GO:0032201)3.72184688
23electron transport chain (GO:0022900)3.71492317
24negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.69932967
25protein complex biogenesis (GO:0070271)3.68413525
26guanosine-containing compound biosynthetic process (GO:1901070)3.68290251
27anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.67777435
28sperm-egg recognition (GO:0035036)3.66959683
29nucleobase biosynthetic process (GO:0046112)3.64596550
30regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.64497868
31GDP-mannose metabolic process (GO:0019673)3.64426497
32formation of translation preinitiation complex (GO:0001731)3.62227830
33DNA strand elongation (GO:0022616)3.62199337
34ribosomal small subunit assembly (GO:0000028)3.61499119
35mitochondrial respiratory chain complex assembly (GO:0033108)3.59133386
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.57870518
37protein maturation by protein folding (GO:0022417)3.57523357
38ribosomal small subunit biogenesis (GO:0042274)3.54784651
39protein deneddylation (GO:0000338)3.53276362
40DNA replication checkpoint (GO:0000076)3.52459182
41rRNA modification (GO:0000154)3.49693347
42deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.46550611
43regulation of cilium movement (GO:0003352)3.44277142
44telomere maintenance via recombination (GO:0000722)3.41531467
45base-excision repair, AP site formation (GO:0006285)3.40939436
46negative regulation of ligase activity (GO:0051352)3.40902577
47negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.40902577
48sperm motility (GO:0030317)3.38536126
49pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.37277349
50respiratory chain complex IV assembly (GO:0008535)3.37141579
51cullin deneddylation (GO:0010388)3.36720862
52protein localization to chromosome, centromeric region (GO:0071459)3.34372270
53DNA replication initiation (GO:0006270)3.34037626
54fusion of sperm to egg plasma membrane (GO:0007342)3.32316041
55iron-sulfur cluster assembly (GO:0016226)3.32199118
56metallo-sulfur cluster assembly (GO:0031163)3.32199118
57protein neddylation (GO:0045116)3.31578923
58mitochondrial respiratory chain complex I assembly (GO:0032981)3.31552048
59NADH dehydrogenase complex assembly (GO:0010257)3.31552048
60mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.31552048
61rRNA methylation (GO:0031167)3.31394200
62GTP biosynthetic process (GO:0006183)3.31109303
63chromatin remodeling at centromere (GO:0031055)3.30354233
64maturation of SSU-rRNA (GO:0030490)3.29049766
657-methylguanosine mRNA capping (GO:0006370)3.26921182
66CENP-A containing nucleosome assembly (GO:0034080)3.26510109
67piRNA metabolic process (GO:0034587)3.26428475
68motile cilium assembly (GO:0044458)3.26240356
69positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.25959977
70tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24520466
71RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24520466
72transcription elongation from RNA polymerase III promoter (GO:0006385)3.24405187
73termination of RNA polymerase III transcription (GO:0006386)3.24405187
74cellular component biogenesis (GO:0044085)3.23845188
75spliceosomal snRNP assembly (GO:0000387)3.23157296
76positive regulation of cell cycle arrest (GO:0071158)3.22091929
77nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.19829697
78regulation of cellular amino acid metabolic process (GO:0006521)3.19296424
79regulation of cellular amine metabolic process (GO:0033238)3.18884722
80cytochrome complex assembly (GO:0017004)3.18748062
81DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.17091520
82cell-cell recognition (GO:0009988)3.17058398
83histone exchange (GO:0043486)3.16887367
84DNA damage response, detection of DNA damage (GO:0042769)3.16619167
85UTP biosynthetic process (GO:0006228)3.16153431
86RNA capping (GO:0036260)3.15919655
877-methylguanosine RNA capping (GO:0009452)3.15919655
88DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.15759434
89cilium or flagellum-dependent cell motility (GO:0001539)3.12079671
90positive regulation of ligase activity (GO:0051351)3.11418084
91DNA replication-dependent nucleosome assembly (GO:0006335)3.11180856
92DNA replication-dependent nucleosome organization (GO:0034723)3.11180856
93negative regulation of protein ubiquitination (GO:0031397)3.10525647
94signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.09859528
95intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.09859528
96exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.09789608
97signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.09756617
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.09756617
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.09756617
100protein localization to kinetochore (GO:0034501)3.09451765
101viral transcription (GO:0019083)3.08608772
102transcription-coupled nucleotide-excision repair (GO:0006283)3.07964121
103pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.07072118
104ribosome biogenesis (GO:0042254)3.06633276
105pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.06145887
106spermatid development (GO:0007286)3.05334236
107mitotic recombination (GO:0006312)3.04990122
108peptidyl-histidine modification (GO:0018202)3.04496119
109metaphase plate congression (GO:0051310)3.04484471
110synaptonemal complex organization (GO:0070193)3.04409814
111synaptonemal complex assembly (GO:0007130)3.03290262
112antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.02855442
113regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.02002939
114signal transduction involved in DNA damage checkpoint (GO:0072422)3.01582299
115signal transduction involved in DNA integrity checkpoint (GO:0072401)3.01582299
116pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.99731806
117regulation of ubiquitin-protein transferase activity (GO:0051438)2.99669503
118L-serine metabolic process (GO:0006563)2.99043108
119negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.98870687
120ribosomal large subunit biogenesis (GO:0042273)2.98419968
121signal transduction involved in cell cycle checkpoint (GO:0072395)2.98415489
122pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.97317078
123DNA replication-independent nucleosome organization (GO:0034724)2.93901829
124DNA replication-independent nucleosome assembly (GO:0006336)2.93901829
125attachment of spindle microtubules to kinetochore (GO:0008608)2.91292363
126nucleotide-excision repair, DNA gap filling (GO:0006297)2.90662145
127epithelial cilium movement (GO:0003351)2.89134686
128ribonucleoprotein complex biogenesis (GO:0022613)2.88940958
129regulation of ligase activity (GO:0051340)2.88562729
130transcription elongation from RNA polymerase II promoter (GO:0006368)2.88551716
131SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.86559220
132antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.86420303
133UTP metabolic process (GO:0046051)2.85169213
134L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.85099847
135establishment of chromosome localization (GO:0051303)2.85000514
136ribosome assembly (GO:0042255)2.84201249
137CTP biosynthetic process (GO:0006241)2.83172920
138CTP metabolic process (GO:0046036)2.83172920
139telomere maintenance via telomere lengthening (GO:0010833)2.83030947
140rRNA processing (GO:0006364)2.81976301
141cell cycle G1/S phase transition (GO:0044843)2.80859343
142G1/S transition of mitotic cell cycle (GO:0000082)2.80859343
143multicellular organism reproduction (GO:0032504)2.80845712
144microtubule depolymerization (GO:0007019)2.80582048
145chromosome condensation (GO:0030261)2.80449974
146deoxyribonucleotide biosynthetic process (GO:0009263)2.79839219
147translation (GO:0006412)2.78380191

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.16389228
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.91446466
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.78357928
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.55180610
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.54799905
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.54471961
7* GABP_17652178_ChIP-ChIP_JURKAT_Human3.41667019
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.23320670
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.07433480
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.00476003
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.98808875
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.85753751
13FOXM1_23109430_ChIP-Seq_U2OS_Human2.81967519
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.81613084
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.60388271
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.47437049
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.38147581
18VDR_23849224_ChIP-Seq_CD4+_Human2.35839788
19* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33629952
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.28445476
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.22970127
22XRN2_22483619_ChIP-Seq_HELA_Human2.18559455
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.14912937
24* GABP_19822575_ChIP-Seq_HepG2_Human2.14117125
25DCP1A_22483619_ChIP-Seq_HELA_Human2.12387098
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06667980
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.00006942
28E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99043194
29FOXP3_21729870_ChIP-Seq_TREG_Human1.94860084
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.89525393
31SRF_21415370_ChIP-Seq_HL-1_Mouse1.88820579
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.86531462
33SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.81437901
34PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.76310030
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75638148
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73554940
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69688079
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.67737488
39ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.66207733
40E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65700912
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64939425
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.64858183
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64593397
44TTF2_22483619_ChIP-Seq_HELA_Human1.61935354
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.60021421
46AR_21909140_ChIP-Seq_LNCAP_Human1.56962626
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52639655
48ELK1_19687146_ChIP-ChIP_HELA_Human1.49201743
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45422240
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.42445471
51* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.42378891
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41117297
53HOXB4_20404135_ChIP-ChIP_EML_Mouse1.41036953
54CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36287404
55CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.33847753
56KDM5A_27292631_Chip-Seq_BREAST_Human1.33676512
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29101508
58CIITA_25753668_ChIP-Seq_RAJI_Human1.26493620
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26088895
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25128982
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.22293748
62ELF1_20517297_ChIP-Seq_JURKAT_Human1.22018131
63* FOXP1_21924763_ChIP-Seq_HESCs_Human1.21423764
64SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.20422778
65TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18909384
66SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.17011085
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.15800512
68KLF4_18555785_ChIP-Seq_MESCs_Mouse1.14030404
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.13882273
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13496910
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.12131581
72YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08718844
73HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07436408
74E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06933223
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.05529144
76PADI4_21655091_ChIP-ChIP_MCF-7_Human1.04186816
77ELK1_22589737_ChIP-Seq_MCF10A_Human1.03551378
78ZNF263_19887448_ChIP-Seq_K562_Human1.03215771
79KAP1_22055183_ChIP-Seq_ESCs_Mouse1.01320125
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.01038934
81* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98369947
82BCL6_27268052_Chip-Seq_Bcells_Human0.97766755
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96614788
84DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96217945
85CTCF_18555785_ChIP-Seq_MESCs_Mouse0.95767992
86TFEB_21752829_ChIP-Seq_HELA_Human0.95446588
87YY1_22570637_ChIP-Seq_MALME-3M_Human0.95191362
88CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.95155990
89CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93868104
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93344648
91P68_20966046_ChIP-Seq_HELA_Human0.92229700
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91835786
93RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91670142
94NOTCH1_21737748_ChIP-Seq_TLL_Human0.91168444
95TBX5_21415370_ChIP-Seq_HL-1_Mouse0.91055413
96ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90208545
97RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88258727
98TET1_21451524_ChIP-Seq_MESCs_Mouse0.88234777
99TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.88022701
100SPI1_23547873_ChIP-Seq_NB4_Human0.87567325
101BCOR_27268052_Chip-Seq_Bcells_Human0.87063121
102PU.1_20513432_ChIP-Seq_Bcells_Mouse0.86955975
103MYC_18940864_ChIP-ChIP_HL60_Human0.84201660
104CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84019237
105EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.83693409
106GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82217536
107CTCF_26484167_Chip-Seq_Bcells_Mouse0.81945142
108SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.81052011
109CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.80962899
110SRY_22984422_ChIP-ChIP_TESTIS_Rat0.80612320
111* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80110744
112SOX2_18555785_ChIP-Seq_MESCs_Mouse0.78856193

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.90882811
2MP0005410_abnormal_fertilization4.22682600
3MP0004957_abnormal_blastocyst_morpholog4.02487825
4MP0003111_abnormal_nucleus_morphology3.79187229
5MP0010094_abnormal_chromosome_stability3.56942187
6MP0003077_abnormal_cell_cycle3.37386683
7MP0008058_abnormal_DNA_repair3.03692423
8MP0008877_abnormal_DNA_methylation2.86068502
9MP0008007_abnormal_cellular_replicative2.59405536
10MP0001929_abnormal_gametogenesis2.54671975
11MP0003718_maternal_effect2.47388732
12MP0008932_abnormal_embryonic_tissue2.41750456
13MP0008057_abnormal_DNA_replication2.34548806
14MP0003786_premature_aging2.32823100
15MP0004147_increased_porphyrin_level2.21851023
16MP0005083_abnormal_biliary_tract2.20600831
17MP0005499_abnormal_olfactory_system2.18674198
18MP0005394_taste/olfaction_phenotype2.18674198
19MP0002210_abnormal_sex_determination2.06601776
20MP0001529_abnormal_vocalization2.02470952
21MP0002653_abnormal_ependyma_morphology1.97715075
22MP0003698_abnormal_male_reproductive1.93326556
23MP0003186_abnormal_redox_activity1.93252253
24MP0002132_abnormal_respiratory_system1.88744104
25MP0000372_irregular_coat_pigmentation1.80202961
26MP0001730_embryonic_growth_arrest1.76567289
27MP0003123_paternal_imprinting1.75661151
28MP0001145_abnormal_male_reproductive1.73619607
29MP0002160_abnormal_reproductive_system1.68913057
30MP0009333_abnormal_splenocyte_physiolog1.68704954
31MP0003011_delayed_dark_adaptation1.62012569
32MP0000653_abnormal_sex_gland1.60466822
33MP0008260_abnormal_autophagy1.57752934
34MP0003806_abnormal_nucleotide_metabolis1.56446663
35MP0006036_abnormal_mitochondrial_physio1.55788098
36MP0002736_abnormal_nociception_after1.52722538
37MP0001905_abnormal_dopamine_level1.51651860
38MP0000350_abnormal_cell_proliferation1.50408205
39MP0000490_abnormal_crypts_of1.47523398
40MP0003646_muscle_fatigue1.40836528
41MP0005397_hematopoietic_system_phenotyp1.36020588
42MP0001545_abnormal_hematopoietic_system1.36020588
43MP0002161_abnormal_fertility/fecundity1.35143316
44MP0005389_reproductive_system_phenotype1.33160023
45MP0005501_abnormal_skin_physiology1.32814619
46MP0000313_abnormal_cell_death1.32402203
47MP0000358_abnormal_cell_content/1.30819143
48MP0002019_abnormal_tumor_incidence1.30446636
49MP0004142_abnormal_muscle_tone1.29346561
50MP0005075_abnormal_melanosome_morpholog1.25897332
51MP0010307_abnormal_tumor_latency1.20126284
52MP0002080_prenatal_lethality1.19805013
53MP0001697_abnormal_embryo_size1.17636560
54MP0006054_spinal_hemorrhage1.12770008
55MP0001764_abnormal_homeostasis1.12276177
56MP0002277_abnormal_respiratory_mucosa1.11094006
57MP0001672_abnormal_embryogenesis/_devel1.09606224
58MP0005380_embryogenesis_phenotype1.09606224
59MP0001119_abnormal_female_reproductive1.08892291
60MP0002163_abnormal_gland_morphology1.06260202
61MP0006276_abnormal_autonomic_nervous1.05743834
62MP0003880_abnormal_central_pattern1.04922994
63MP0005636_abnormal_mineral_homeostasis1.04054388
64MP0002396_abnormal_hematopoietic_system1.03412327
65MP0000049_abnormal_middle_ear1.02442380
66MP0004133_heterotaxia1.01873429
67MP0003315_abnormal_perineum_morphology1.01336241
68MP0005408_hypopigmentation0.99486855
69MP0000678_abnormal_parathyroid_gland0.97092177
70MP0005220_abnormal_exocrine_pancreas0.96236735
71MP0008789_abnormal_olfactory_epithelium0.95514329
72MP0002102_abnormal_ear_morphology0.94093289
73MP0000858_altered_metastatic_potential0.92898917
74MP0003656_abnormal_erythrocyte_physiolo0.92896946
75MP0004808_abnormal_hematopoietic_stem0.92783486
76MP0004782_abnormal_surfactant_physiolog0.92494125
77MP0001968_abnormal_touch/_nociception0.92456680
78MP0003984_embryonic_growth_retardation0.92394648
79MP0001919_abnormal_reproductive_system0.92075551
80MP0002085_abnormal_embryonic_tissue0.90303703
81MP0001542_abnormal_bone_strength0.90184544
82MP0005058_abnormal_lysosome_morphology0.89477939
83MP0001835_abnormal_antigen_presentation0.87874599
84MP0002088_abnormal_embryonic_growth/wei0.87679697
85MP0002938_white_spotting0.87306580
86MP0002822_catalepsy0.85833896
87MP0006035_abnormal_mitochondrial_morpho0.84843689
88MP0008995_early_reproductive_senescence0.84673956
89MP0005395_other_phenotype0.84214978
90MP0002693_abnormal_pancreas_physiology0.83665900
91MP0009785_altered_susceptibility_to0.82656384
92MP0000689_abnormal_spleen_morphology0.81931502
93MP0002398_abnormal_bone_marrow0.81374915
94MP0002751_abnormal_autonomic_nervous0.80999551
95MP0008873_increased_physiological_sensi0.78927306
96MP0002722_abnormal_immune_system0.78291376
97MP0006292_abnormal_olfactory_placode0.77377067
98MP0001756_abnormal_urination0.75306390
99MP0002429_abnormal_blood_cell0.74722703
100MP0001944_abnormal_pancreas_morphology0.73942008
101MP0003763_abnormal_thymus_physiology0.73342163
102MP0009840_abnormal_foam_cell0.73056413
103MP0002405_respiratory_system_inflammati0.71909971
104MP0003699_abnormal_female_reproductive0.71802649
105MP0001873_stomach_inflammation0.70220284
106MP0001346_abnormal_lacrimal_gland0.69591138
107MP0005451_abnormal_body_composition0.68316534
108MP0000685_abnormal_immune_system0.68025365
109MP0005671_abnormal_response_to0.67942630
110MP0009643_abnormal_urine_homeostasis0.67766803
111MP0002084_abnormal_developmental_patter0.66907230
112MP0000703_abnormal_thymus_morphology0.66101102
113MP0010030_abnormal_orbit_morphology0.66081293
114MP0005384_cellular_phenotype0.66054971
115MP0005084_abnormal_gallbladder_morpholo0.64839529
116MP0000716_abnormal_immune_system0.63476947
117MP0009764_decreased_sensitivity_to0.62804701
118MP0008875_abnormal_xenobiotic_pharmacok0.61546698
119MP0005367_renal/urinary_system_phenotyp0.61201058
120MP0000516_abnormal_urinary_system0.61201058
121MP0001727_abnormal_embryo_implantation0.60961762
122MP0002234_abnormal_pharynx_morphology0.60798121
123MP0004264_abnormal_extraembryonic_tissu0.60681575
124MP0001293_anophthalmia0.60595485
125MP0000750_abnormal_muscle_regeneration0.60404471
126MP0002148_abnormal_hypersensitivity_rea0.60178716
127MP0009379_abnormal_foot_pigmentation0.60139933
128MP0002638_abnormal_pupillary_reflex0.59749194
129MP0001881_abnormal_mammary_gland0.59574200
130MP0005423_abnormal_somatic_nervous0.59485223
131MP0009765_abnormal_xenobiotic_induced0.58410542
132MP0003436_decreased_susceptibility_to0.58217032
133MP0001853_heart_inflammation0.58068611
134MP0001986_abnormal_taste_sensitivity0.57698964
135MP0005379_endocrine/exocrine_gland_phen0.56991204
136MP0005319_abnormal_enzyme/_coenzyme0.56927587
137MP0000343_altered_response_to0.55471196

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.40170582
2Chronic bronchitis (HP:0004469)4.83973774
3Abnormal respiratory motile cilium physiology (HP:0012261)4.05802313
4Increased hepatocellular lipid droplets (HP:0006565)3.97779256
5Rhinitis (HP:0012384)3.97672053
6Progressive macrocephaly (HP:0004481)3.93918188
7Increased intramyocellular lipid droplets (HP:0012240)3.91751560
8Abnormal respiratory motile cilium morphology (HP:0005938)3.89330142
9Abnormal respiratory epithelium morphology (HP:0012253)3.89330142
10Renal Fanconi syndrome (HP:0001994)3.86702584
11Absent/shortened dynein arms (HP:0200106)3.84032951
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.84032951
13Lipid accumulation in hepatocytes (HP:0006561)3.73109681
14Birth length less than 3rd percentile (HP:0003561)3.68999081
15Abnormal gallbladder physiology (HP:0012438)3.54279055
16Cholecystitis (HP:0001082)3.54279055
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.45744697
18Increased muscle lipid content (HP:0009058)3.42838810
19Abnormality of the anterior horn cell (HP:0006802)3.36253128
20Degeneration of anterior horn cells (HP:0002398)3.36253128
21Abnormal number of erythroid precursors (HP:0012131)3.32767339
22Oral leukoplakia (HP:0002745)3.29990488
23Abnormality of cells of the erythroid lineage (HP:0012130)3.29073108
24Lactic acidosis (HP:0003128)3.28052367
25Infertility (HP:0000789)3.16260403
26Microvesicular hepatic steatosis (HP:0001414)3.15051247
27Aplastic anemia (HP:0001915)3.13555658
28Rough bone trabeculation (HP:0100670)3.13288439
29Nasal polyposis (HP:0100582)3.11874362
303-Methylglutaconic aciduria (HP:0003535)3.11833725
31Carpal bone hypoplasia (HP:0001498)3.10612867
32Bronchitis (HP:0012387)3.09913685
33Cerebral edema (HP:0002181)3.03493700
34Abnormal ciliary motility (HP:0012262)3.02996382
35Breast hypoplasia (HP:0003187)2.98962036
36Bronchiectasis (HP:0002110)2.94769550
37Microretrognathia (HP:0000308)2.93920837
38Male infertility (HP:0003251)2.93909057
39Exercise intolerance (HP:0003546)2.93556098
40Pancreatic fibrosis (HP:0100732)2.90847265
41Impulsivity (HP:0100710)2.86697401
42Abnormal spermatogenesis (HP:0008669)2.82427638
43Patellar aplasia (HP:0006443)2.82304972
44Respiratory failure (HP:0002878)2.79050664
45Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.77158809
46Decreased activity of mitochondrial respiratory chain (HP:0008972)2.77158809
47Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.75792500
48Reticulocytopenia (HP:0001896)2.73998000
49Aplasia/Hypoplasia of the patella (HP:0006498)2.70684106
50Increased serum pyruvate (HP:0003542)2.70264981
51Secondary amenorrhea (HP:0000869)2.69497381
52Pancreatic cysts (HP:0001737)2.67643260
53Emotional lability (HP:0000712)2.64235789
54Cerebral hypomyelination (HP:0006808)2.63876247
55Respiratory difficulties (HP:0002880)2.63294843
56Hypoplasia of the capital femoral epiphysis (HP:0003090)2.62740482
57Progressive microcephaly (HP:0000253)2.60608962
58Abnormality of glycolysis (HP:0004366)2.59110746
59Abnormality of the nasal mucosa (HP:0000433)2.54689509
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.51107861
61Type I transferrin isoform profile (HP:0003642)2.49296908
62Exertional dyspnea (HP:0002875)2.48105915
63Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.48004907
64Multiple enchondromatosis (HP:0005701)2.42596012
6511 pairs of ribs (HP:0000878)2.41340257
66Facial cleft (HP:0002006)2.34665940
67Poor head control (HP:0002421)2.33461351
68Testicular atrophy (HP:0000029)2.32549207
69Opisthotonus (HP:0002179)2.31537046
70Premature ovarian failure (HP:0008209)2.31370239
71Hypoplastic pelvis (HP:0008839)2.28017271
72True hermaphroditism (HP:0010459)2.27430438
73Optic disc pallor (HP:0000543)2.26952454
74Abnormal trabecular bone morphology (HP:0100671)2.26313519
75Acute necrotizing encephalopathy (HP:0006965)2.23013200
76Retinal dysplasia (HP:0007973)2.22859748
77Meckel diverticulum (HP:0002245)2.18686215
78Ragged-red muscle fibers (HP:0003200)2.17174889
79Cleft eyelid (HP:0000625)2.16452914
80Aplasia/hypoplasia of the uterus (HP:0008684)2.16396856
81Abnormality of the preputium (HP:0100587)2.16173375
82CNS demyelination (HP:0007305)2.16003436
83Abnormal mitochondria in muscle tissue (HP:0008316)2.15320506
84Hepatic necrosis (HP:0002605)2.14659924
85Increased IgM level (HP:0003496)2.14236791
86Bone marrow hypocellularity (HP:0005528)2.12185188
87Abnormal protein glycosylation (HP:0012346)2.10881761
88Abnormal glycosylation (HP:0012345)2.10881761
89Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.10881761
90Abnormal protein N-linked glycosylation (HP:0012347)2.10881761
91Abnormality of the heme biosynthetic pathway (HP:0010472)2.10553772
92Macrocytic anemia (HP:0001972)2.09735070
93Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.09432590
94Abnormality of the ileum (HP:0001549)2.07325742
95Trismus (HP:0000211)2.07135093
96Leukodystrophy (HP:0002415)2.06692484
97Gout (HP:0001997)2.02980522
98Hepatocellular necrosis (HP:0001404)2.01845758
99Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.01014520
100Absent epiphyses (HP:0010577)2.01014520
101Mitochondrial inheritance (HP:0001427)2.00687969
102Lethargy (HP:0001254)1.99855641
103Death in infancy (HP:0001522)1.99706886
104CNS hypomyelination (HP:0003429)1.97219276
105Cellular immunodeficiency (HP:0005374)1.96706536
106Premature graying of hair (HP:0002216)1.96422150
107Severe visual impairment (HP:0001141)1.95926694
108Recurrent bronchitis (HP:0002837)1.93873625
109Methylmalonic aciduria (HP:0012120)1.93060528
110Congenital ichthyosiform erythroderma (HP:0007431)1.92611510
111Increased CSF lactate (HP:0002490)1.92540529
112Pallor (HP:0000980)1.90514021
113Abnormality of renal resorption (HP:0011038)1.90463631
114Delusions (HP:0000746)1.90320521
115Hypoplasia of the pons (HP:0012110)1.90290176
116Molar tooth sign on MRI (HP:0002419)1.90195297
117Abnormality of midbrain morphology (HP:0002418)1.90195297
118Increased serum lactate (HP:0002151)1.89948326
119Muscle fiber atrophy (HP:0100295)1.89260796
120Cholelithiasis (HP:0001081)1.89210418
121Sparse eyelashes (HP:0000653)1.88960764
122Aplasia/Hypoplasia of the uvula (HP:0010293)1.88916435
123Hypokinesia (HP:0002375)1.88606736
124Pancytopenia (HP:0001876)1.86831985
125Sloping forehead (HP:0000340)1.86656169
126Acute encephalopathy (HP:0006846)1.86492393
127Nephronophthisis (HP:0000090)1.86268334
128Irregular epiphyses (HP:0010582)1.85346983
129Selective tooth agenesis (HP:0001592)1.84184820
130X-linked dominant inheritance (HP:0001423)1.84067421
131Hyperalaninemia (HP:0003348)1.84046931
132Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.84046931
133Abnormality of alanine metabolism (HP:0010916)1.84046931
134Reduced antithrombin III activity (HP:0001976)1.83942890
135Horseshoe kidney (HP:0000085)1.83449884
136Recurrent otitis media (HP:0000403)1.83197807
137Absent thumb (HP:0009777)1.83177713
138Thrombocytosis (HP:0001894)1.82771159
139Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.82732492
140Abnormality of the pons (HP:0007361)1.82552334
141Azoospermia (HP:0000027)1.80544350
142Poor suck (HP:0002033)1.79840127
143Personality changes (HP:0000751)1.79058654
144Postnatal microcephaly (HP:0005484)1.78105510
145Type 2 muscle fiber atrophy (HP:0003554)1.78000988
146Abnormality of chromosome stability (HP:0003220)1.77175296
147Myelodysplasia (HP:0002863)1.76709935
148Flat capital femoral epiphysis (HP:0003370)1.76429692
149Atrophy/Degeneration involving motor neurons (HP:0007373)1.76105358
150Gliosis (HP:0002171)1.75091314
151Optic nerve coloboma (HP:0000588)1.74085207
152Neoplasm of the pancreas (HP:0002894)1.73769635
153Upper limb muscle weakness (HP:0003484)1.73383146
154Recurrent sinusitis (HP:0011108)1.73342185
155Progressive muscle weakness (HP:0003323)1.72147959
156Supernumerary spleens (HP:0009799)1.71515060
157Abnormality of the labia minora (HP:0012880)1.70618418
158Pulmonary fibrosis (HP:0002206)1.69783243
159Spastic paraparesis (HP:0002313)1.68212631
160Hypertensive crisis (HP:0100735)1.67382977
161Abnormal gallbladder morphology (HP:0012437)1.66287737
162Hypoplasia of the uterus (HP:0000013)1.66255439
163Type II lissencephaly (HP:0007260)1.65884387
164Entropion (HP:0000621)1.64948597

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.00370464
2BUB14.96674485
3WEE13.55280323
4TESK13.50393507
5STK163.17339768
6EIF2AK13.09260105
7PLK42.98071080
8PDK32.73050916
9PDK42.73050916
10NEK22.58448423
11BRSK22.47380920
12NME22.39061631
13EIF2AK32.11789862
14TESK22.07746410
15SRPK12.04595483
16MAP4K22.00655242
17DYRK31.98133717
18CDC71.94183516
19BRAF1.91075558
20VRK11.84453545
21PASK1.82181109
22TTK1.78842225
23BRSK11.75111433
24PLK11.69306394
25CCNB11.66540067
26PIM21.66325253
27TLK11.61599082
28PDK21.61446385
29ACVR1B1.60955399
30TRIM281.55599171
31RPS6KA41.55223546
32PRKD31.46472051
33CSNK1G31.40391399
34AURKB1.35944268
35AURKA1.30446339
36MAP2K71.29526046
37BCKDK1.28253489
38CHEK21.22237276
39STK38L1.10044449
40NEK11.09717644
41ERN11.09206684
42DAPK11.09008469
43CSNK1G21.08946244
44MAPKAPK31.08742130
45CDK191.08286052
46ARAF1.08195323
47MAP3K111.05438625
48TSSK61.04401100
49PLK31.03700280
50CSNK1A1L1.03203913
51CDK70.96952813
52EPHA20.96070794
53ATR0.95816551
54CSNK1G10.90368004
55MAPK150.90107252
56ZAK0.90099596
57NUAK10.89448698
58SIK30.83301622
59KDR0.81578323
60MAP3K80.79315330
61PIM10.76205829
62PAK40.76078490
63SCYL20.74536394
64CDK80.72932843
65PAK10.71987284
66MKNK20.71982128
67RAF10.71058429
68MAP3K120.69914539
69LIMK10.68304081
70ZAP700.67943600
71CSNK2A10.66210230
72AKT30.66040671
73IRAK30.65250786
74DYRK20.64421471
75CDK40.64140087
76EIF2AK20.63921131
77STK40.63476591
78NME10.61814913
79RPS6KB20.61709125
80DYRK1B0.61369184
81CHEK10.61204360
82MST40.58879184
83TAOK10.58385745
84STK100.58354009
85MKNK10.57666876
86ABL20.55802720
87BCR0.53926661
88EEF2K0.53535014
89STK30.53451847
90MAP3K100.53104078
91CDK140.52585579
92PRKCI0.52401057
93PINK10.52091947
94MAP3K30.51749941
95LMTK20.51316101
96PAK60.50960822
97SMG10.49880494
98LRRK20.48301926
99WNK30.46702539
100CDK11A0.46476180
101RPS6KA50.45516141
102CLK10.44557044
103PBK0.44294639
104CSNK2A20.44075393
105BLK0.43537957
106NEK90.43436511
107IKBKB0.43240011
108ATM0.36779136
109CDK180.36621707
110TAF10.36482370
111MAP3K50.36353302
112CDK20.36142402
113ILK0.36138438
114CDK150.35307889
115MAP4K10.34921172
116MAP2K20.34584292
117TYK20.34302172
118FLT30.34120316
119IRAK10.33145692
120TBK10.33011948
121AKT20.32498357
122MATK0.31513368
123TEC0.29823324
124TXK0.29587933
125DAPK30.29047052
126PIK3CG0.28361045
127IRAK20.27975769
128TAOK20.27205905
129NLK0.27035266
130LATS20.26652894
131BTK0.25447093
132IRAK40.25428710
133EPHB20.25243785
134GRK60.24389329
135MUSK0.22784441

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.23520932
2DNA replication_Homo sapiens_hsa030304.05702663
3RNA polymerase_Homo sapiens_hsa030203.71163911
4Ribosome_Homo sapiens_hsa030103.27775705
5Mismatch repair_Homo sapiens_hsa034303.19734161
6Pyrimidine metabolism_Homo sapiens_hsa002402.95980743
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.95255503
8Base excision repair_Homo sapiens_hsa034102.74242545
9RNA transport_Homo sapiens_hsa030132.60991033
10Spliceosome_Homo sapiens_hsa030402.59117994
11Homologous recombination_Homo sapiens_hsa034402.56111212
12Protein export_Homo sapiens_hsa030602.52357443
13Vitamin B6 metabolism_Homo sapiens_hsa007502.47004482
14Nucleotide excision repair_Homo sapiens_hsa034202.43245772
15Basal transcription factors_Homo sapiens_hsa030222.22893999
16Cell cycle_Homo sapiens_hsa041102.21774038
17Fatty acid elongation_Homo sapiens_hsa000621.94730012
18Fanconi anemia pathway_Homo sapiens_hsa034601.85129085
19Purine metabolism_Homo sapiens_hsa002301.74462571
20Folate biosynthesis_Homo sapiens_hsa007901.70073301
21RNA degradation_Homo sapiens_hsa030181.63174888
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.43172650
23Huntingtons disease_Homo sapiens_hsa050161.41425536
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.40821936
25One carbon pool by folate_Homo sapiens_hsa006701.40612632
26Pentose phosphate pathway_Homo sapiens_hsa000301.36762196
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32319274
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.30812029
29Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.30560236
30Selenocompound metabolism_Homo sapiens_hsa004501.27397910
31Non-homologous end-joining_Homo sapiens_hsa034501.26509048
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.26048386
33p53 signaling pathway_Homo sapiens_hsa041151.22382592
34Oxidative phosphorylation_Homo sapiens_hsa001901.20829844
35Parkinsons disease_Homo sapiens_hsa050121.16334261
36Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.14743314
37Epstein-Barr virus infection_Homo sapiens_hsa051691.12506797
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.11086032
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.11015082
40Glutathione metabolism_Homo sapiens_hsa004801.08308165
41Sulfur relay system_Homo sapiens_hsa041221.05657346
42mRNA surveillance pathway_Homo sapiens_hsa030151.04451791
43Cardiac muscle contraction_Homo sapiens_hsa042600.98675899
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.98520981
45Regulation of autophagy_Homo sapiens_hsa041400.96415727
46Systemic lupus erythematosus_Homo sapiens_hsa053220.94903660
47Antigen processing and presentation_Homo sapiens_hsa046120.93032799
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.91328953
49Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89994791
50Legionellosis_Homo sapiens_hsa051340.87548896
51Steroid biosynthesis_Homo sapiens_hsa001000.87183812
52Fructose and mannose metabolism_Homo sapiens_hsa000510.85531136
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84204441
54Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.78895343
55N-Glycan biosynthesis_Homo sapiens_hsa005100.78575862
56Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76117388
57Oocyte meiosis_Homo sapiens_hsa041140.74001272
58Biosynthesis of amino acids_Homo sapiens_hsa012300.72442002
59Carbon metabolism_Homo sapiens_hsa012000.69799543
60Pyruvate metabolism_Homo sapiens_hsa006200.67593621
61Linoleic acid metabolism_Homo sapiens_hsa005910.67185585
62Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.66903510
63Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.66254587
64Arachidonic acid metabolism_Homo sapiens_hsa005900.65480459
65Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.63077194
66Herpes simplex infection_Homo sapiens_hsa051680.61683735
67Viral carcinogenesis_Homo sapiens_hsa052030.59532553
68Metabolic pathways_Homo sapiens_hsa011000.59181419
69Galactose metabolism_Homo sapiens_hsa000520.59005651
70Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58303424
71Other glycan degradation_Homo sapiens_hsa005110.57309850
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56211555
73Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.55614961
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.54663442
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53663073
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51983179
77Synaptic vesicle cycle_Homo sapiens_hsa047210.50903422
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48457261
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.48379657
80Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.45780766
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44880515
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44811054
83Alzheimers disease_Homo sapiens_hsa050100.40016659
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39565993
85Fatty acid metabolism_Homo sapiens_hsa012120.37429784
86Propanoate metabolism_Homo sapiens_hsa006400.35966625
87Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35518612
88HTLV-I infection_Homo sapiens_hsa051660.30723626
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.28782970
90Vibrio cholerae infection_Homo sapiens_hsa051100.28688481
91Apoptosis_Homo sapiens_hsa042100.28224819
92Alcoholism_Homo sapiens_hsa050340.28080952
93Phototransduction_Homo sapiens_hsa047440.27577626
94Thyroid cancer_Homo sapiens_hsa052160.27551114
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27143576
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26559520
97Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26487343
98Glycerophospholipid metabolism_Homo sapiens_hsa005640.26405403
99Sulfur metabolism_Homo sapiens_hsa009200.25683476
100Butanoate metabolism_Homo sapiens_hsa006500.25016929
101Primary immunodeficiency_Homo sapiens_hsa053400.22325914
102Phenylalanine metabolism_Homo sapiens_hsa003600.21973754
103Renin-angiotensin system_Homo sapiens_hsa046140.21598873
104Shigellosis_Homo sapiens_hsa051310.20890941
105Glycosaminoglycan degradation_Homo sapiens_hsa005310.18800270
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.18701293
107Influenza A_Homo sapiens_hsa051640.18280914
108Arginine and proline metabolism_Homo sapiens_hsa003300.16965839
109Measles_Homo sapiens_hsa051620.16931305
110Fat digestion and absorption_Homo sapiens_hsa049750.16885920
111Vitamin digestion and absorption_Homo sapiens_hsa049770.16565753
112Lysosome_Homo sapiens_hsa041420.16395230
113Peroxisome_Homo sapiens_hsa041460.14993498
114Salmonella infection_Homo sapiens_hsa051320.14923981
115Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.14447551
116Primary bile acid biosynthesis_Homo sapiens_hsa001200.13965492
117NF-kappa B signaling pathway_Homo sapiens_hsa040640.13539363
118Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.12929013
119Bladder cancer_Homo sapiens_hsa052190.12039106
120beta-Alanine metabolism_Homo sapiens_hsa004100.11609884
121Type I diabetes mellitus_Homo sapiens_hsa049400.11059490
122Intestinal immune network for IgA production_Homo sapiens_hsa046720.11042285
123Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.10587381
124Collecting duct acid secretion_Homo sapiens_hsa049660.10509795
125Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.08524136
126Rheumatoid arthritis_Homo sapiens_hsa053230.08309532
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.06912011

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