Rank | Gene Set | Z-score |
---|---|---|
1 | actin-myosin filament sliding (GO:0033275) | 5.64021583 |
2 | muscle filament sliding (GO:0030049) | 5.64021583 |
3 | myofibril assembly (GO:0030239) | 5.37258902 |
4 | synaptic vesicle maturation (GO:0016188) | 5.33006697 |
5 | sarcomere organization (GO:0045214) | 5.04540001 |
6 | cell junction maintenance (GO:0034331) | 4.93985479 |
7 | cardiac myofibril assembly (GO:0055003) | 4.86723327 |
8 | cell-cell junction maintenance (GO:0045217) | 4.82451700 |
9 | actin-mediated cell contraction (GO:0070252) | 4.69203488 |
10 | cardiac chamber formation (GO:0003207) | 4.54450039 |
11 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.53560785 |
12 | regulation of the force of heart contraction (GO:0002026) | 4.45967157 |
13 | locomotory exploration behavior (GO:0035641) | 4.43655870 |
14 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.35179487 |
15 | outflow tract septum morphogenesis (GO:0003148) | 4.30832235 |
16 | cardiac muscle contraction (GO:0060048) | 4.19581822 |
17 | striated muscle contraction (GO:0006941) | 3.99434052 |
18 | regulation of cardioblast differentiation (GO:0051890) | 3.99119869 |
19 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.96185050 |
20 | cardiac muscle hypertrophy (GO:0003300) | 3.78565642 |
21 | sodium ion export (GO:0071436) | 3.77593855 |
22 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.75661985 |
23 | glutamate secretion (GO:0014047) | 3.73313273 |
24 | atrial septum morphogenesis (GO:0060413) | 3.66124976 |
25 | actomyosin structure organization (GO:0031032) | 3.65135368 |
26 | neuronal action potential propagation (GO:0019227) | 3.63114013 |
27 | synaptic vesicle exocytosis (GO:0016079) | 3.61886784 |
28 | striated muscle hypertrophy (GO:0014897) | 3.58195365 |
29 | layer formation in cerebral cortex (GO:0021819) | 3.57371759 |
30 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.57309427 |
31 | cerebellar Purkinje cell layer development (GO:0021680) | 3.54307647 |
32 | actin filament-based movement (GO:0030048) | 3.54019689 |
33 | venous blood vessel morphogenesis (GO:0048845) | 3.53375670 |
34 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.48934361 |
35 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.48604165 |
36 | activation of protein kinase A activity (GO:0034199) | 3.48453928 |
37 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.48089761 |
38 | endocardial cushion morphogenesis (GO:0003203) | 3.47326103 |
39 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.41792316 |
40 | neuromuscular process controlling posture (GO:0050884) | 3.40935728 |
41 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.37910979 |
42 | skeletal muscle contraction (GO:0003009) | 3.36480277 |
43 | epithelial cell-cell adhesion (GO:0090136) | 3.33377866 |
44 | adult heart development (GO:0007512) | 3.31604731 |
45 | regulation of actin filament-based movement (GO:1903115) | 3.30724884 |
46 | glycine transport (GO:0015816) | 3.29872478 |
47 | regulation of relaxation of muscle (GO:1901077) | 3.29864679 |
48 | muscle hypertrophy (GO:0014896) | 3.29800562 |
49 | muscle tissue morphogenesis (GO:0060415) | 3.29377287 |
50 | regulation of early endosome to late endosome transport (GO:2000641) | 3.27978754 |
51 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.27686183 |
52 | negative regulation of microtubule polymerization (GO:0031115) | 3.27091547 |
53 | cardiac right ventricle morphogenesis (GO:0003215) | 3.23901194 |
54 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.21812038 |
55 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.20186517 |
56 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.20143535 |
57 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.18480682 |
58 | cardiac ventricle formation (GO:0003211) | 3.17540258 |
59 | cardiac conduction (GO:0061337) | 3.15933341 |
60 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.14968348 |
61 | relaxation of cardiac muscle (GO:0055119) | 3.14620404 |
62 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.14171330 |
63 | regulation of synapse structural plasticity (GO:0051823) | 3.14083725 |
64 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.12826085 |
65 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.12826085 |
66 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.12728464 |
67 | muscle hypertrophy in response to stress (GO:0003299) | 3.12728464 |
68 | cardiac muscle adaptation (GO:0014887) | 3.12728464 |
69 | cardiac muscle cell development (GO:0055013) | 3.12488188 |
70 | exploration behavior (GO:0035640) | 3.11245110 |
71 | neurotransmitter secretion (GO:0007269) | 3.11085513 |
72 | regulation of synaptic vesicle transport (GO:1902803) | 3.10629185 |
73 | cellular potassium ion homeostasis (GO:0030007) | 3.08247677 |
74 | regulation of skeletal muscle contraction (GO:0014819) | 3.08014471 |
75 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.06858619 |
76 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.05000051 |
77 | cellular component maintenance (GO:0043954) | 3.03954953 |
78 | neuromuscular process controlling balance (GO:0050885) | 3.03411958 |
79 | inner ear receptor cell differentiation (GO:0060113) | 3.03296769 |
80 | cell migration in hindbrain (GO:0021535) | 3.01755717 |
81 | cell communication by electrical coupling (GO:0010644) | 3.00857699 |
82 | response to inactivity (GO:0014854) | 2.97740646 |
83 | axon ensheathment in central nervous system (GO:0032291) | 2.96988556 |
84 | central nervous system myelination (GO:0022010) | 2.96988556 |
85 | gamma-aminobutyric acid transport (GO:0015812) | 2.96577879 |
86 | muscle cell fate commitment (GO:0042693) | 2.95594141 |
87 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.94872836 |
88 | cardiac cell development (GO:0055006) | 2.93164751 |
89 | heart valve formation (GO:0003188) | 2.91558403 |
90 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.89592452 |
91 | dendritic spine morphogenesis (GO:0060997) | 2.88058798 |
92 | membrane repolarization during action potential (GO:0086011) | 2.87370749 |
93 | regulation of heart rate (GO:0002027) | 2.86430154 |
94 | establishment of mitochondrion localization (GO:0051654) | 2.84906687 |
95 | regulation of membrane repolarization (GO:0060306) | 2.84588281 |
96 | vocalization behavior (GO:0071625) | 2.84491372 |
97 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.83495008 |
98 | regulation of autophagic vacuole assembly (GO:2000785) | 2.83406426 |
99 | muscle contraction (GO:0006936) | 2.80617129 |
100 | negative regulation of myotube differentiation (GO:0010832) | 2.80423254 |
101 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 2.79434016 |
102 | detection of temperature stimulus (GO:0016048) | 2.78955214 |
103 | mesenchyme morphogenesis (GO:0072132) | 2.78832777 |
104 | neuronal ion channel clustering (GO:0045161) | 2.76926176 |
105 | regulation of striated muscle contraction (GO:0006942) | 2.76479216 |
106 | striated muscle adaptation (GO:0014888) | 2.75135334 |
107 | regulation of ARF GTPase activity (GO:0032312) | 2.73476393 |
108 | negative regulation of cell size (GO:0045792) | 2.71520011 |
109 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.71087511 |
110 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.70747010 |
111 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.69543799 |
112 | proline transport (GO:0015824) | 2.69176811 |
113 | positive regulation of sodium ion transport (GO:0010765) | 2.68817929 |
114 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 2.67964969 |
115 | regulation of heart contraction (GO:0008016) | 2.67735155 |
116 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.67517387 |
117 | muscle system process (GO:0003012) | 2.65743882 |
118 | regulation of ARF protein signal transduction (GO:0032012) | 2.65409423 |
119 | negative regulation of hormone biosynthetic process (GO:0032353) | 2.64443054 |
120 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.64351804 |
121 | mitochondrion transport along microtubule (GO:0047497) | 2.64351804 |
122 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.62407445 |
123 | creatine metabolic process (GO:0006600) | 2.61745957 |
124 | plasma membrane repair (GO:0001778) | 2.60703059 |
125 | atrioventricular valve morphogenesis (GO:0003181) | 2.60357720 |
126 | response to parathyroid hormone (GO:0071107) | 2.58935024 |
127 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.58913949 |
128 | protein retention in ER lumen (GO:0006621) | 2.58610980 |
129 | mating behavior (GO:0007617) | 2.57387224 |
130 | cellular response to glucagon stimulus (GO:0071377) | 2.57077814 |
131 | regulation of ATPase activity (GO:0043462) | 2.57069323 |
132 | regulation of ATP catabolic process (GO:1903289) | 2.57069323 |
133 | regulation of cardioblast proliferation (GO:0003264) | 2.56114041 |
134 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.56114041 |
135 | protein localization to synapse (GO:0035418) | 2.55941030 |
136 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.55579219 |
137 | calcium ion-dependent exocytosis (GO:0017156) | 2.55204199 |
138 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.54829151 |
139 | positive regulation of membrane potential (GO:0045838) | 2.53797658 |
140 | L-phenylalanine metabolic process (GO:0006558) | 2.51896678 |
141 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.51896678 |
142 | potassium ion import (GO:0010107) | 2.49000477 |
143 | dendrite morphogenesis (GO:0048813) | 2.48152160 |
144 | localization within membrane (GO:0051668) | 2.47784165 |
145 | neuron cell-cell adhesion (GO:0007158) | 2.46219884 |
146 | axon cargo transport (GO:0008088) | 2.46053294 |
147 | dopamine receptor signaling pathway (GO:0007212) | 2.45392581 |
148 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.45375816 |
149 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.45052931 |
150 | response to dietary excess (GO:0002021) | 2.43861298 |
151 | cardiac muscle tissue development (GO:0048738) | 2.43727919 |
152 | neurotransmitter transport (GO:0006836) | 2.42483833 |
153 | muscle fiber development (GO:0048747) | 2.42036462 |
154 | protein maturation by protein folding (GO:0022417) | 2.41461843 |
155 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.41236256 |
156 | glycogen catabolic process (GO:0005980) | 2.40395950 |
157 | response to methylmercury (GO:0051597) | 2.39071108 |
158 | potassium ion homeostasis (GO:0055075) | 2.38777385 |
159 | long-term memory (GO:0007616) | 2.38624996 |
160 | muscle adaptation (GO:0043500) | 2.37856140 |
161 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.37504960 |
162 | growth hormone secretion (GO:0030252) | 2.36978127 |
163 | camera-type eye morphogenesis (GO:0048593) | 2.36481843 |
164 | regulation of synaptic plasticity (GO:0048167) | 2.36030525 |
165 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.35717613 |
166 | axon ensheathment (GO:0008366) | 2.35465295 |
167 | ensheathment of neurons (GO:0007272) | 2.35465295 |
168 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.34646220 |
169 | suckling behavior (GO:0001967) | 2.34636867 |
170 | cellular sodium ion homeostasis (GO:0006883) | 2.34104714 |
171 | heart valve morphogenesis (GO:0003179) | 2.33781437 |
172 | adrenergic receptor signaling pathway (GO:0071875) | 2.33745737 |
173 | nerve growth factor signaling pathway (GO:0038180) | 2.33355214 |
174 | multicellular organismal signaling (GO:0035637) | 2.33278322 |
175 | positive regulation of synapse maturation (GO:0090129) | 2.33250531 |
176 | regulation of neurotransmitter levels (GO:0001505) | 2.32872315 |
177 | urinary tract smooth muscle contraction (GO:0014848) | 2.32468677 |
178 | positive regulation of fatty acid oxidation (GO:0046321) | 2.31925302 |
179 | positive regulation of myotube differentiation (GO:0010831) | 2.31105265 |
180 | mannose metabolic process (GO:0006013) | 2.31053560 |
181 | organelle transport along microtubule (GO:0072384) | 2.30896506 |
182 | myelination (GO:0042552) | 2.30498578 |
183 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.29999263 |
184 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.29969301 |
185 | membrane repolarization (GO:0086009) | 2.28811244 |
186 | negative regulation of axonogenesis (GO:0050771) | 2.27488486 |
187 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.27137136 |
188 | adenosine receptor signaling pathway (GO:0001973) | 2.26254717 |
189 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.26152425 |
190 | dendritic spine organization (GO:0097061) | 2.25344804 |
191 | cell communication involved in cardiac conduction (GO:0086065) | 2.24893189 |
192 | negative regulation of nucleotide catabolic process (GO:0030812) | 2.24748215 |
193 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.23761619 |
194 | alanine transport (GO:0032328) | 2.23070092 |
195 | CDP-diacylglycerol metabolic process (GO:0046341) | 2.22988750 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 3.01093763 |
2 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.81719488 |
3 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.71463516 |
4 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.71255548 |
5 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.51722113 |
6 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.41703129 |
7 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.38752118 |
8 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.26374358 |
9 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 2.24297139 |
10 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.19514775 |
11 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.08401470 |
12 | KDM2B_26808549_Chip-Seq_K562_Human | 2.03981103 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.02608830 |
14 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.00587151 |
15 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.99446773 |
16 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.99446773 |
17 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.98880105 |
18 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.98654259 |
19 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.97333906 |
20 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.97016810 |
21 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.96137708 |
22 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.90420045 |
23 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.89798505 |
24 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.89229020 |
25 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.87269502 |
26 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.87147112 |
27 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.86912766 |
28 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.85824180 |
29 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.83982972 |
30 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.83497354 |
31 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.80459686 |
32 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.80401354 |
33 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.78466585 |
34 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.74770206 |
35 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.72765076 |
36 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.67469840 |
37 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.64528303 |
38 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.63385832 |
39 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.63281947 |
40 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.60385165 |
41 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.59832426 |
42 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.58348742 |
43 | P68_20966046_ChIP-Seq_HELA_Human | 1.58287340 |
44 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.56245447 |
45 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.55783289 |
46 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.54372773 |
47 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.53936334 |
48 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.53831155 |
49 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.52869375 |
50 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.51428406 |
51 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.50610196 |
52 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.46830412 |
53 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.46333255 |
54 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.46087079 |
55 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.45617537 |
56 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.44775074 |
57 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.44003711 |
58 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.42453641 |
59 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.40788995 |
60 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.39402563 |
61 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.37638752 |
62 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.36762244 |
63 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.36272838 |
64 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.36047262 |
65 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.35152507 |
66 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.34932582 |
67 | MYC_22102868_ChIP-Seq_BL_Human | 1.34190970 |
68 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.34041867 |
69 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.33374244 |
70 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.31801201 |
71 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.31455813 |
72 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.30003491 |
73 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.29906024 |
74 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28325207 |
75 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.27869269 |
76 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.27706070 |
77 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.27635022 |
78 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.27283686 |
79 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.25996199 |
80 | SA1_27219007_Chip-Seq_Bcells_Human | 1.25816326 |
81 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.25650389 |
82 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.24174822 |
83 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.23722450 |
84 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.22727722 |
85 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.21750282 |
86 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.20817010 |
87 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.19728884 |
88 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.19152076 |
89 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.17688898 |
90 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.17301856 |
91 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.16814342 |
92 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.16206947 |
93 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.14782298 |
94 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.13353305 |
95 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.13024750 |
96 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.13024750 |
97 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.12125645 |
98 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.11220196 |
99 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.11111009 |
100 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.11029849 |
101 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.09558331 |
102 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 1.08720617 |
103 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 1.08375788 |
104 | GATA1_19941826_ChIP-Seq_K562_Human | 1.08216098 |
105 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.07671899 |
106 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.06728315 |
107 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.05601165 |
108 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.04700616 |
109 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.03507327 |
110 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.02853003 |
111 | KLF4_19829295_ChIP-Seq_ESCs_Human | 1.02053232 |
112 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00534144 |
113 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.99586526 |
114 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.99291985 |
115 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.99047352 |
116 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.97425511 |
117 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.97127013 |
118 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.97090130 |
119 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.97006556 |
120 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.95546727 |
121 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.93129423 |
122 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91353620 |
123 | SMAD4_21741376_ChIP-Seq_ESCs_Human | 0.91236073 |
124 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.89886685 |
125 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.88394474 |
126 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.88348796 |
127 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.87700249 |
128 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.86240839 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.24673857 |
2 | MP0004084_abnormal_cardiac_muscle | 3.88070415 |
3 | MP0004036_abnormal_muscle_relaxation | 3.69123495 |
4 | MP0003329_amyloid_beta_deposits | 3.42599600 |
5 | MP0004270_analgesia | 3.36916111 |
6 | MP0004858_abnormal_nervous_system | 3.17917378 |
7 | MP0003635_abnormal_synaptic_transmissio | 3.14130699 |
8 | MP0003646_muscle_fatigue | 3.01091155 |
9 | MP0004510_myositis | 2.95210937 |
10 | MP0008775_abnormal_heart_ventricle | 2.76919786 |
11 | MP0003880_abnormal_central_pattern | 2.74418322 |
12 | MP0002909_abnormal_adrenal_gland | 2.57359073 |
13 | MP0002972_abnormal_cardiac_muscle | 2.49921007 |
14 | MP0002064_seizures | 2.46024794 |
15 | MP0004215_abnormal_myocardial_fiber | 2.41627918 |
16 | MP0005620_abnormal_muscle_contractility | 2.38645229 |
17 | MP0003283_abnormal_digestive_organ | 2.28801688 |
18 | MP0009745_abnormal_behavioral_response | 2.24245455 |
19 | MP0002063_abnormal_learning/memory/cond | 2.22926539 |
20 | MP0009840_abnormal_foam_cell | 2.20931596 |
21 | MP0002733_abnormal_thermal_nociception | 2.17478881 |
22 | MP0001968_abnormal_touch/_nociception | 2.12268426 |
23 | MP0001485_abnormal_pinna_reflex | 2.11437710 |
24 | MP0001348_abnormal_lacrimal_gland | 2.07094528 |
25 | MP0002822_catalepsy | 2.04240912 |
26 | MP0002106_abnormal_muscle_physiology | 2.01468187 |
27 | MP0002272_abnormal_nervous_system | 1.99119130 |
28 | MP0009780_abnormal_chondrocyte_physiolo | 1.97251274 |
29 | MP0004087_abnormal_muscle_fiber | 1.94628988 |
30 | MP0002734_abnormal_mechanical_nocicepti | 1.90297201 |
31 | MP0000749_muscle_degeneration | 1.89458376 |
32 | MP0005083_abnormal_biliary_tract | 1.88675442 |
33 | MP0001970_abnormal_pain_threshold | 1.86473740 |
34 | MP0000013_abnormal_adipose_tissue | 1.83381160 |
35 | MP0000920_abnormal_myelination | 1.78452212 |
36 | MP0000604_amyloidosis | 1.78145667 |
37 | MP0002572_abnormal_emotion/affect_behav | 1.78012818 |
38 | MP0005423_abnormal_somatic_nervous | 1.77991819 |
39 | MP0000750_abnormal_muscle_regeneration | 1.77976881 |
40 | MP0000955_abnormal_spinal_cord | 1.73080898 |
41 | MP0008569_lethality_at_weaning | 1.70283277 |
42 | MP0002249_abnormal_larynx_morphology | 1.69174301 |
43 | MP0005369_muscle_phenotype | 1.68592061 |
44 | MP0000751_myopathy | 1.68465525 |
45 | MP0004885_abnormal_endolymph | 1.67879140 |
46 | MP0002735_abnormal_chemical_nociception | 1.67668125 |
47 | MP0008961_abnormal_basal_metabolism | 1.66639262 |
48 | MP0009046_muscle_twitch | 1.58687519 |
49 | MP0002736_abnormal_nociception_after | 1.56819662 |
50 | MP0000759_abnormal_skeletal_muscle | 1.55697765 |
51 | MP0002127_abnormal_cardiovascular_syste | 1.55338732 |
52 | MP0004811_abnormal_neuron_physiology | 1.54538787 |
53 | MP0000747_muscle_weakness | 1.52668025 |
54 | MP0001544_abnormal_cardiovascular_syste | 1.49673892 |
55 | MP0005385_cardiovascular_system_phenoty | 1.49673892 |
56 | MP0003634_abnormal_glial_cell | 1.49364445 |
57 | MP0000003_abnormal_adipose_tissue | 1.46720419 |
58 | MP0001486_abnormal_startle_reflex | 1.45616178 |
59 | MP0010630_abnormal_cardiac_muscle | 1.43529096 |
60 | MP0003172_abnormal_lysosome_physiology | 1.43453791 |
61 | MP0003279_aneurysm | 1.41949385 |
62 | MP0003633_abnormal_nervous_system | 1.36693314 |
63 | MP0002837_dystrophic_cardiac_calcinosis | 1.36467379 |
64 | MP0004742_abnormal_vestibular_system | 1.36098881 |
65 | MP0002066_abnormal_motor_capabilities/c | 1.30136955 |
66 | MP0006138_congestive_heart_failure | 1.28852027 |
67 | MP0002067_abnormal_sensory_capabilities | 1.28851395 |
68 | MP0002254_reproductive_system_inflammat | 1.28753010 |
69 | MP0009384_cardiac_valve_regurgitation | 1.28108437 |
70 | MP0002184_abnormal_innervation | 1.26398786 |
71 | MP0004142_abnormal_muscle_tone | 1.23563132 |
72 | MP0003195_calcinosis | 1.22836274 |
73 | MP0003075_altered_response_to | 1.22045735 |
74 | MP0000733_abnormal_muscle_development | 1.21610496 |
75 | MP0005058_abnormal_lysosome_morphology | 1.21559112 |
76 | MP0003122_maternal_imprinting | 1.21038014 |
77 | MP0005623_abnormal_meninges_morphology | 1.21009351 |
78 | MP0000778_abnormal_nervous_system | 1.20795938 |
79 | MP0004043_abnormal_pH_regulation | 1.20559973 |
80 | MP0001440_abnormal_grooming_behavior | 1.18724266 |
81 | MP0002882_abnormal_neuron_morphology | 1.16378733 |
82 | MP0005645_abnormal_hypothalamus_physiol | 1.16137633 |
83 | MP0003690_abnormal_glial_cell | 1.14785756 |
84 | MP0004145_abnormal_muscle_electrophysio | 1.12471983 |
85 | MP0008874_decreased_physiological_sensi | 1.12329894 |
86 | MP0006276_abnormal_autonomic_nervous | 1.09415348 |
87 | MP0004924_abnormal_behavior | 1.07017053 |
88 | MP0005386_behavior/neurological_phenoty | 1.07017053 |
89 | MP0002557_abnormal_social/conspecific_i | 1.06344270 |
90 | MP0005451_abnormal_body_composition | 1.06049410 |
91 | MP0004233_abnormal_muscle_weight | 1.03659697 |
92 | MP0003631_nervous_system_phenotype | 1.03504230 |
93 | MP0010030_abnormal_orbit_morphology | 1.03504116 |
94 | MP0004130_abnormal_muscle_cell | 1.00805059 |
95 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.00334977 |
96 | MP0003705_abnormal_hypodermis_morpholog | 0.97939092 |
97 | MP0003137_abnormal_impulse_conducting | 0.96827982 |
98 | MP0002089_abnormal_postnatal_growth/wei | 0.95979586 |
99 | MP0002108_abnormal_muscle_morphology | 0.95435006 |
100 | MP0000026_abnormal_inner_ear | 0.95012260 |
101 | MP0002653_abnormal_ependyma_morphology | 0.93217963 |
102 | MP0003879_abnormal_hair_cell | 0.92819749 |
103 | MP0002069_abnormal_eating/drinking_beha | 0.92603269 |
104 | MP0001501_abnormal_sleep_pattern | 0.91599831 |
105 | MP0004484_altered_response_of | 0.90891240 |
106 | MP0002332_abnormal_exercise_endurance | 0.90759077 |
107 | MP0009379_abnormal_foot_pigmentation | 0.89739166 |
108 | MP0000767_abnormal_smooth_muscle | 0.89605295 |
109 | MP0002152_abnormal_brain_morphology | 0.88821880 |
110 | MP0002229_neurodegeneration | 0.88606544 |
111 | MP0001299_abnormal_eye_distance/ | 0.87923436 |
112 | MP0001529_abnormal_vocalization | 0.87686180 |
113 | MP0005167_abnormal_blood-brain_barrier | 0.85301585 |
114 | MP0005535_abnormal_body_temperature | 0.84788377 |
115 | MP0001502_abnormal_circadian_rhythm | 0.82586085 |
116 | MP0002118_abnormal_lipid_homeostasis | 0.82122795 |
117 | MP0001905_abnormal_dopamine_level | 0.81929072 |
118 | MP0005332_abnormal_amino_acid | 0.81127677 |
119 | MP0002269_muscular_atrophy | 0.80164774 |
120 | MP0005375_adipose_tissue_phenotype | 0.79874727 |
121 | MP0005503_abnormal_tendon_morphology | 0.79478687 |
122 | MP0001765_abnormal_ion_homeostasis | 0.79349756 |
123 | MP0000538_abnormal_urinary_bladder | 0.77256504 |
124 | MP0000230_abnormal_systemic_arterial | 0.74737409 |
125 | MP0004133_heterotaxia | 0.74722380 |
126 | MP0000534_abnormal_ureter_morphology | 0.72972736 |
127 | MP0003942_abnormal_urinary_system | 0.72972060 |
128 | MP0003656_abnormal_erythrocyte_physiolo | 0.72855636 |
129 | MP0001944_abnormal_pancreas_morphology | 0.72670514 |
130 | MP0001963_abnormal_hearing_physiology | 0.72355720 |
131 | MP0004085_abnormal_heartbeat | 0.71738081 |
132 | MP0003300_gastrointestinal_ulcer | 0.71397778 |
133 | MP0003632_abnormal_nervous_system | 0.71170949 |
134 | MP0000678_abnormal_parathyroid_gland | 0.71133042 |
135 | MP0002078_abnormal_glucose_homeostasis | 0.70369451 |
136 | MP0001664_abnormal_digestion | 0.70018423 |
137 | MP0000639_abnormal_adrenal_gland | 0.68633815 |
138 | MP0008872_abnormal_physiological_respon | 0.68595292 |
139 | MP0000266_abnormal_heart_morphology | 0.68078836 |
140 | MP0000462_abnormal_digestive_system | 0.67918299 |
141 | MP0005330_cardiomyopathy | 0.66332596 |
142 | MP0010329_abnormal_lipoprotein_level | 0.66059029 |
143 | MP0005595_abnormal_vascular_smooth | 0.65903461 |
144 | MP0002876_abnormal_thyroid_physiology | 0.65519092 |
145 | MP0009250_abnormal_appendicular_skeleto | 0.64061649 |
146 | MP0003123_paternal_imprinting | 0.62252564 |
147 | MP0003045_fibrosis | 0.60489340 |
148 | MP0005448_abnormal_energy_balance | 0.59523094 |
149 | MP0005248_abnormal_Harderian_gland | 0.58298128 |
150 | MP0005381_digestive/alimentary_phenotyp | 0.56820452 |
151 | MP0002971_abnormal_brown_adipose | 0.55724807 |
152 | MP0009053_abnormal_anal_canal | 0.54758468 |
153 | MP0000537_abnormal_urethra_morphology | 0.53637254 |
154 | MP0002933_joint_inflammation | 0.52462340 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 5.32667212 |
2 | Ventricular tachycardia (HP:0004756) | 4.80543344 |
3 | Type 1 muscle fiber predominance (HP:0003803) | 4.59480382 |
4 | Atrial fibrillation (HP:0005110) | 4.42035482 |
5 | Supranuclear gaze palsy (HP:0000605) | 4.33486624 |
6 | Patent foramen ovale (HP:0001655) | 4.16808280 |
7 | Muscle fiber inclusion bodies (HP:0100299) | 4.06459172 |
8 | Neurofibrillary tangles (HP:0002185) | 4.04436491 |
9 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.02956281 |
10 | Primary atrial arrhythmia (HP:0001692) | 4.00581672 |
11 | Supraventricular tachycardia (HP:0004755) | 3.88949424 |
12 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.82154757 |
13 | Calf muscle hypertrophy (HP:0008981) | 3.80213672 |
14 | Supraventricular arrhythmia (HP:0005115) | 3.79525597 |
15 | Exercise-induced myalgia (HP:0003738) | 3.73291847 |
16 | Syncope (HP:0001279) | 3.72516121 |
17 | Nemaline bodies (HP:0003798) | 3.68317303 |
18 | Ulnar deviation of the wrist (HP:0003049) | 3.63576175 |
19 | Cerebral inclusion bodies (HP:0100314) | 3.56190199 |
20 | Hip contracture (HP:0003273) | 3.48191389 |
21 | Round ear (HP:0100830) | 3.48057689 |
22 | Subaortic stenosis (HP:0001682) | 3.44166056 |
23 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.44166056 |
24 | Visual hallucinations (HP:0002367) | 3.40955014 |
25 | Distal arthrogryposis (HP:0005684) | 3.39043899 |
26 | Fetal akinesia sequence (HP:0001989) | 3.38320890 |
27 | Muscle fiber splitting (HP:0003555) | 3.37541567 |
28 | Ventricular arrhythmia (HP:0004308) | 3.34609940 |
29 | Abnormality of the calf musculature (HP:0001430) | 3.30893787 |
30 | Hypoplastic ischia (HP:0003175) | 3.30545667 |
31 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 3.29835044 |
32 | Hyporeflexia of lower limbs (HP:0002600) | 3.25475815 |
33 | Ankle clonus (HP:0011448) | 3.20046540 |
34 | Insomnia (HP:0100785) | 3.11244719 |
35 | Prolonged QT interval (HP:0001657) | 3.09772810 |
36 | Depression (HP:0000716) | 3.01019213 |
37 | Hypercortisolism (HP:0001578) | 2.99941262 |
38 | Lipoatrophy (HP:0100578) | 2.98188931 |
39 | Abnormal EKG (HP:0003115) | 2.97094722 |
40 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.94817671 |
41 | Pheochromocytoma (HP:0002666) | 2.88689149 |
42 | Heart block (HP:0012722) | 2.86719564 |
43 | EMG: myopathic abnormalities (HP:0003458) | 2.85322384 |
44 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.83502811 |
45 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.83502811 |
46 | Abnormality of glycolipid metabolism (HP:0010969) | 2.83502811 |
47 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.82331797 |
48 | Achilles tendon contracture (HP:0001771) | 2.82154964 |
49 | Abnormality of the ischium (HP:0003174) | 2.81551656 |
50 | Congenital malformation of the right heart (HP:0011723) | 2.80140492 |
51 | Double outlet right ventricle (HP:0001719) | 2.80140492 |
52 | Megalencephaly (HP:0001355) | 2.79922647 |
53 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.79528655 |
54 | Abnormal atrioventricular conduction (HP:0005150) | 2.77278231 |
55 | Action tremor (HP:0002345) | 2.75493959 |
56 | Abnormality of the Achilles tendon (HP:0005109) | 2.73403648 |
57 | Left ventricular hypertrophy (HP:0001712) | 2.72327046 |
58 | Distal lower limb muscle weakness (HP:0009053) | 2.70394507 |
59 | Myopathic facies (HP:0002058) | 2.68824119 |
60 | Focal motor seizures (HP:0011153) | 2.65318411 |
61 | Dilated cardiomyopathy (HP:0001644) | 2.61769991 |
62 | Torticollis (HP:0000473) | 2.58790334 |
63 | Anxiety (HP:0000739) | 2.58621246 |
64 | Limited hip movement (HP:0008800) | 2.53734187 |
65 | Bradycardia (HP:0001662) | 2.53275674 |
66 | Focal seizures (HP:0007359) | 2.53122467 |
67 | Neuroendocrine neoplasm (HP:0100634) | 2.49407198 |
68 | Dysostosis multiplex (HP:0000943) | 2.48639100 |
69 | Abnormality of the aortic arch (HP:0012303) | 2.48013169 |
70 | Exercise-induced muscle cramps (HP:0003710) | 2.47349582 |
71 | Upper limb amyotrophy (HP:0009129) | 2.47229264 |
72 | Distal upper limb amyotrophy (HP:0007149) | 2.47229264 |
73 | Spastic gait (HP:0002064) | 2.45175278 |
74 | Focal dystonia (HP:0004373) | 2.41337058 |
75 | Absent phalangeal crease (HP:0006109) | 2.39625610 |
76 | Abnormality of the pubic bones (HP:0003172) | 2.39199185 |
77 | Craniofacial dystonia (HP:0012179) | 2.38334650 |
78 | Turricephaly (HP:0000262) | 2.37864299 |
79 | Rapidly progressive (HP:0003678) | 2.33587944 |
80 | Dysmetria (HP:0001310) | 2.33487278 |
81 | Agitation (HP:0000713) | 2.32861707 |
82 | Decreased circulating renin level (HP:0003351) | 2.32387197 |
83 | Annular pancreas (HP:0001734) | 2.31961167 |
84 | Ventricular fibrillation (HP:0001663) | 2.27958853 |
85 | Urinary urgency (HP:0000012) | 2.27759088 |
86 | Hyperparathyroidism (HP:0000843) | 2.27468871 |
87 | Hyperacusis (HP:0010780) | 2.21853620 |
88 | Right ventricular cardiomyopathy (HP:0011663) | 2.17454371 |
89 | Intention tremor (HP:0002080) | 2.17307140 |
90 | Peripheral hypomyelination (HP:0007182) | 2.17050322 |
91 | Increased variability in muscle fiber diameter (HP:0003557) | 2.16774524 |
92 | Papilledema (HP:0001085) | 2.16256402 |
93 | Ketoacidosis (HP:0001993) | 2.14233712 |
94 | Abnormality of the lower motor neuron (HP:0002366) | 2.13918543 |
95 | Postural instability (HP:0002172) | 2.11467819 |
96 | Termporal pattern (HP:0011008) | 2.07788516 |
97 | Insidious onset (HP:0003587) | 2.07788516 |
98 | Neoplasm of the heart (HP:0100544) | 2.07773085 |
99 | Neuronal loss in central nervous system (HP:0002529) | 2.06676702 |
100 | Broad metatarsal (HP:0001783) | 2.06540004 |
101 | Hand muscle atrophy (HP:0009130) | 2.04957028 |
102 | EMG: neuropathic changes (HP:0003445) | 2.04787708 |
103 | Generalized muscle weakness (HP:0003324) | 2.04010671 |
104 | Bundle branch block (HP:0011710) | 2.03557224 |
105 | Abnormal eating behavior (HP:0100738) | 2.03404756 |
106 | Calcaneovalgus deformity (HP:0001848) | 2.03402459 |
107 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.03318219 |
108 | Abnormality of the corticospinal tract (HP:0002492) | 2.02841477 |
109 | Myotonia (HP:0002486) | 2.01727507 |
110 | Psychosis (HP:0000709) | 2.01560647 |
111 | Growth hormone excess (HP:0000845) | 2.00937317 |
112 | Athetosis (HP:0002305) | 2.00454529 |
113 | Scanning speech (HP:0002168) | 2.00284292 |
114 | Myoglobinuria (HP:0002913) | 1.99569930 |
115 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.99321231 |
116 | Deep palmar crease (HP:0006191) | 1.98533403 |
117 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.98499695 |
118 | Aplasia of the musculature (HP:0100854) | 1.97881289 |
119 | Rigidity (HP:0002063) | 1.95213559 |
120 | Metatarsus adductus (HP:0001840) | 1.94459433 |
121 | Diminished motivation (HP:0000745) | 1.94213171 |
122 | Hyperkalemia (HP:0002153) | 1.93879983 |
123 | Menstrual irregularities (HP:0000858) | 1.93037825 |
124 | Large for gestational age (HP:0001520) | 1.92222111 |
125 | Late onset (HP:0003584) | 1.91536115 |
126 | Bulbar palsy (HP:0001283) | 1.90904135 |
127 | Ketosis (HP:0001946) | 1.90594422 |
128 | Impaired social interactions (HP:0000735) | 1.88027079 |
129 | Abnormal social behavior (HP:0012433) | 1.88027079 |
130 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.87863548 |
131 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.87863548 |
132 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.87863548 |
133 | Cerebral hypomyelination (HP:0006808) | 1.86530692 |
134 | Clonus (HP:0002169) | 1.86298569 |
135 | Delusions (HP:0000746) | 1.86238410 |
136 | Difficulty climbing stairs (HP:0003551) | 1.86140029 |
137 | Truncus arteriosus (HP:0001660) | 1.85423206 |
138 | Progressive muscle weakness (HP:0003323) | 1.84906785 |
139 | Morphological abnormality of the middle ear (HP:0008609) | 1.84495223 |
140 | Loss of speech (HP:0002371) | 1.84278191 |
141 | Hypoventilation (HP:0002791) | 1.84237598 |
142 | Increased connective tissue (HP:0009025) | 1.84164026 |
143 | Abnormality of the neuromuscular junction (HP:0003398) | 1.84023318 |
144 | Fatigable weakness (HP:0003473) | 1.84023318 |
145 | Lymphangioma (HP:0100764) | 1.83620299 |
146 | Adrenal overactivity (HP:0002717) | 1.83136824 |
147 | Overriding aorta (HP:0002623) | 1.83105128 |
148 | Hyperthyroidism (HP:0000836) | 1.82817141 |
149 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.82236826 |
150 | Mucopolysacchariduria (HP:0008155) | 1.82236826 |
151 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.81544694 |
152 | Hammertoe (HP:0001765) | 1.80766748 |
153 | Apathy (HP:0000741) | 1.80564634 |
154 | Nonprogressive disorder (HP:0003680) | 1.78878862 |
155 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.76931902 |
156 | Asymmetric septal hypertrophy (HP:0001670) | 1.76268538 |
157 | Hypoplastic heart (HP:0001961) | 1.76213251 |
158 | Frequent falls (HP:0002359) | 1.75966113 |
159 | Obstructive sleep apnea (HP:0002870) | 1.75533688 |
160 | Bronchomalacia (HP:0002780) | 1.75438048 |
161 | Spastic paraparesis (HP:0002313) | 1.74722646 |
162 | Delayed CNS myelination (HP:0002188) | 1.74432745 |
163 | Deformed tarsal bones (HP:0008119) | 1.74407417 |
164 | Amyotrophic lateral sclerosis (HP:0007354) | 1.74395934 |
165 | Gout (HP:0001997) | 1.73313550 |
166 | Progressive neurologic deterioration (HP:0002344) | 1.73293078 |
167 | Abnormal finger flexion creases (HP:0006143) | 1.72476456 |
168 | Generalized tonic-clonic seizures (HP:0002069) | 1.72146239 |
169 | Mesangial abnormality (HP:0001966) | 1.72065119 |
170 | Sudden death (HP:0001699) | 1.71935405 |
171 | Amblyopia (HP:0000646) | 1.71165542 |
172 | Poor eye contact (HP:0000817) | 1.70828766 |
173 | Onion bulb formation (HP:0003383) | 1.70543982 |
174 | Congenital glaucoma (HP:0001087) | 1.70385798 |
175 | Bilateral microphthalmos (HP:0007633) | 1.70267176 |
176 | Weak cry (HP:0001612) | 1.69861563 |
177 | Back pain (HP:0003418) | 1.69301118 |
178 | Akinesia (HP:0002304) | 1.68989438 |
179 | Absence seizures (HP:0002121) | 1.68771352 |
180 | Pointed chin (HP:0000307) | 1.68473055 |
181 | Hypercalcemia (HP:0003072) | 1.67965565 |
182 | Restlessness (HP:0000711) | 1.67836928 |
183 | Hemiplegia (HP:0002301) | 1.67460241 |
184 | Joint stiffness (HP:0001387) | 1.67243393 |
185 | Anosmia (HP:0000458) | 1.67110808 |
186 | Lower limb muscle weakness (HP:0007340) | 1.66688497 |
187 | Rhabdomyolysis (HP:0003201) | 1.66104467 |
188 | Muscle stiffness (HP:0003552) | 1.64291741 |
189 | Stridor (HP:0010307) | 1.62420175 |
190 | Bell-shaped thorax (HP:0001591) | 1.60552665 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 4.17167714 |
2 | TRIB3 | 3.63043278 |
3 | NTRK1 | 2.74867605 |
4 | KSR2 | 2.56309433 |
5 | MAP3K9 | 2.53035449 |
6 | NTRK3 | 2.41025614 |
7 | WNK3 | 2.37486776 |
8 | ERN1 | 2.23981941 |
9 | TTN | 2.22013679 |
10 | PAK6 | 2.20555670 |
11 | PRKD3 | 2.19437092 |
12 | CDK19 | 2.17842861 |
13 | UHMK1 | 1.97319865 |
14 | ICK | 1.91915102 |
15 | PKN2 | 1.90829967 |
16 | EPHA4 | 1.86287749 |
17 | FRK | 1.84136584 |
18 | TYRO3 | 1.83916080 |
19 | DAPK2 | 1.72435268 |
20 | MINK1 | 1.69638942 |
21 | ARAF | 1.66341684 |
22 | BCKDK | 1.65043686 |
23 | NEK2 | 1.57348864 |
24 | TAOK1 | 1.54210464 |
25 | MARK1 | 1.49967454 |
26 | CAMKK1 | 1.48155163 |
27 | MAP3K11 | 1.46143982 |
28 | WNK4 | 1.43112586 |
29 | SCYL2 | 1.42507659 |
30 | PHKG2 | 1.41191906 |
31 | PHKG1 | 1.41191906 |
32 | TESK2 | 1.31392335 |
33 | NTRK2 | 1.29790128 |
34 | LIMK1 | 1.28331537 |
35 | EPHB1 | 1.28247716 |
36 | MAPK12 | 1.27458680 |
37 | CDK5 | 1.25920654 |
38 | MAP3K1 | 1.24535860 |
39 | MAP3K2 | 1.24527702 |
40 | RET | 1.22870347 |
41 | EPHB2 | 1.22489435 |
42 | STK39 | 1.19647098 |
43 | MAPKAPK3 | 1.18754035 |
44 | LMTK2 | 1.17863848 |
45 | MUSK | 1.16644893 |
46 | MAPK15 | 1.15968197 |
47 | GRK7 | 1.15804222 |
48 | CASK | 1.15082949 |
49 | PRPF4B | 1.13465060 |
50 | EEF2K | 1.09301023 |
51 | PDGFRA | 1.08538919 |
52 | FLT3 | 1.08304033 |
53 | PAK3 | 1.07683142 |
54 | DAPK3 | 1.03592003 |
55 | MAP2K2 | 1.02289823 |
56 | TRPM7 | 1.00646710 |
57 | PRKCH | 1.00550979 |
58 | ALK | 1.00217801 |
59 | CDC42BPA | 1.00072426 |
60 | BMX | 0.98780009 |
61 | MAP2K6 | 0.97025064 |
62 | CDK14 | 0.96531690 |
63 | PDPK1 | 0.96202264 |
64 | LATS2 | 0.92173936 |
65 | RPS6KA2 | 0.91786049 |
66 | HIPK2 | 0.89722834 |
67 | MAP3K10 | 0.89566816 |
68 | OXSR1 | 0.88968524 |
69 | MARK2 | 0.87485742 |
70 | PINK1 | 0.86884740 |
71 | PTK2 | 0.86744861 |
72 | TESK1 | 0.86451723 |
73 | CDK15 | 0.86267271 |
74 | EPHA2 | 0.86023705 |
75 | SIK1 | 0.85619032 |
76 | MAP2K4 | 0.84818789 |
77 | CDK11A | 0.83004774 |
78 | KSR1 | 0.82822755 |
79 | CAMK4 | 0.81323034 |
80 | CAMK1D | 0.80098300 |
81 | CDK18 | 0.79474564 |
82 | FES | 0.77291554 |
83 | DAPK1 | 0.77190545 |
84 | IRAK3 | 0.77079876 |
85 | DDR2 | 0.73434966 |
86 | PDK1 | 0.71667861 |
87 | ILK | 0.71531745 |
88 | MAPKAPK5 | 0.70756079 |
89 | GRK5 | 0.70223617 |
90 | PRKD2 | 0.70126218 |
91 | PRKD1 | 0.69683629 |
92 | MAP3K4 | 0.69611984 |
93 | DMPK | 0.69403353 |
94 | LRRK2 | 0.69005676 |
95 | PRKAA2 | 0.68743317 |
96 | SIK2 | 0.67664125 |
97 | ROCK2 | 0.66987855 |
98 | STK38 | 0.65508263 |
99 | RIPK1 | 0.64647015 |
100 | PRKCG | 0.64409402 |
101 | WNK1 | 0.64195783 |
102 | CAMK1G | 0.64077253 |
103 | MAP3K7 | 0.63071575 |
104 | RAF1 | 0.61234461 |
105 | CAMK1 | 0.60946127 |
106 | MET | 0.57929165 |
107 | RPS6KA6 | 0.57491978 |
108 | CSNK1G2 | 0.56644481 |
109 | ABL2 | 0.55435381 |
110 | CAMK2G | 0.55266275 |
111 | PIK3CA | 0.53643547 |
112 | PRKAA1 | 0.53390236 |
113 | KDR | 0.53189917 |
114 | EPHA3 | 0.52841071 |
115 | MTOR | 0.51880416 |
116 | PTK6 | 0.51605483 |
117 | GRK6 | 0.51187189 |
118 | CAMK2D | 0.51131236 |
119 | RPS6KL1 | 0.50458517 |
120 | RPS6KC1 | 0.50458517 |
121 | DYRK1B | 0.50392352 |
122 | MAPK4 | 0.49749599 |
123 | STK11 | 0.49358774 |
124 | CAMK2B | 0.48907335 |
125 | FGFR4 | 0.48902082 |
126 | ROCK1 | 0.48804830 |
127 | TNIK | 0.48067435 |
128 | PRKCZ | 0.46841047 |
129 | FYN | 0.46239062 |
130 | ACVR1B | 0.44743498 |
131 | MAP2K1 | 0.43874518 |
132 | TNK2 | 0.43741935 |
133 | PRKG2 | 0.43667189 |
134 | SMG1 | 0.43456334 |
135 | PKN1 | 0.43389702 |
136 | BRAF | 0.42441270 |
137 | GRK1 | 0.42280538 |
138 | MAPK7 | 0.41803015 |
139 | TLK1 | 0.41773681 |
140 | CSNK1G3 | 0.41713456 |
141 | MYLK | 0.41132036 |
142 | CAMK2A | 0.40394580 |
143 | ADRBK2 | 0.40048012 |
144 | INSRR | 0.36112428 |
145 | TAOK2 | 0.32858101 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.10588468 |
2 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 3.05089458 |
3 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.95517670 |
4 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.54764779 |
5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.31736846 |
6 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.22436060 |
7 | Insulin secretion_Homo sapiens_hsa04911 | 1.79751729 |
8 | GABAergic synapse_Homo sapiens_hsa04727 | 1.76742847 |
9 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.72762487 |
10 | Olfactory transduction_Homo sapiens_hsa04740 | 1.66198175 |
11 | Long-term potentiation_Homo sapiens_hsa04720 | 1.64178860 |
12 | Circadian entrainment_Homo sapiens_hsa04713 | 1.62395868 |
13 | Cocaine addiction_Homo sapiens_hsa05030 | 1.61851250 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.57470044 |
15 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.56677583 |
16 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.53409788 |
17 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.50862134 |
18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.50546742 |
19 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.48410786 |
20 | Salivary secretion_Homo sapiens_hsa04970 | 1.45952162 |
21 | Other glycan degradation_Homo sapiens_hsa00511 | 1.43741719 |
22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.38637769 |
23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.37794605 |
24 | Morphine addiction_Homo sapiens_hsa05032 | 1.33450102 |
25 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.29858168 |
26 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.27755575 |
27 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.26060768 |
28 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.25911756 |
29 | Gap junction_Homo sapiens_hsa04540 | 1.25542721 |
30 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.21421191 |
31 | Bile secretion_Homo sapiens_hsa04976 | 1.19691744 |
32 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.18783233 |
33 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.18650136 |
34 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.16984241 |
35 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.16829869 |
36 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.14508524 |
37 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.14048755 |
38 | Tight junction_Homo sapiens_hsa04530 | 1.11244726 |
39 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.11167335 |
40 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.10687463 |
41 | Sulfur relay system_Homo sapiens_hsa04122 | 1.10464119 |
42 | Prion diseases_Homo sapiens_hsa05020 | 1.10074951 |
43 | Galactose metabolism_Homo sapiens_hsa00052 | 1.05848021 |
44 | Long-term depression_Homo sapiens_hsa04730 | 1.05702396 |
45 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.05565561 |
46 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.05382443 |
47 | Glioma_Homo sapiens_hsa05214 | 1.01197666 |
48 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.00956055 |
49 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.00827776 |
50 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.00638753 |
51 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.00329435 |
52 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.00263220 |
53 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.99745693 |
54 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.99161712 |
55 | Melanogenesis_Homo sapiens_hsa04916 | 0.99095199 |
56 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.98257298 |
57 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.97229958 |
58 | Nicotine addiction_Homo sapiens_hsa05033 | 0.96445057 |
59 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.96273968 |
60 | Renin secretion_Homo sapiens_hsa04924 | 0.94678925 |
61 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.94377869 |
62 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.90961830 |
63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.89776467 |
64 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.89361957 |
65 | Lysosome_Homo sapiens_hsa04142 | 0.87768877 |
66 | Insulin resistance_Homo sapiens_hsa04931 | 0.87040601 |
67 | Axon guidance_Homo sapiens_hsa04360 | 0.86563019 |
68 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84418695 |
69 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.84028962 |
70 | Endocytosis_Homo sapiens_hsa04144 | 0.83169943 |
71 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.80811510 |
72 | Focal adhesion_Homo sapiens_hsa04510 | 0.80705402 |
73 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.80361750 |
74 | Parkinsons disease_Homo sapiens_hsa05012 | 0.79968385 |
75 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.79563372 |
76 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.79513631 |
77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.78016674 |
78 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.77952679 |
79 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.77550006 |
80 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77202906 |
81 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.77010978 |
82 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.76716638 |
83 | Mineral absorption_Homo sapiens_hsa04978 | 0.76364406 |
84 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.76259460 |
85 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.75149912 |
86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.74821886 |
87 | Bladder cancer_Homo sapiens_hsa05219 | 0.74790022 |
88 | ABC transporters_Homo sapiens_hsa02010 | 0.73955487 |
89 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.72193211 |
90 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.72082530 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.72052823 |
92 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.71849363 |
93 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71277318 |
94 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.70502912 |
95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.69698347 |
96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.68309160 |
97 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.68173059 |
98 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67575691 |
99 | Alzheimers disease_Homo sapiens_hsa05010 | 0.67383060 |
100 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.66971481 |
101 | Amoebiasis_Homo sapiens_hsa05146 | 0.66541122 |
102 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.65746073 |
103 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.64699495 |
104 | Taste transduction_Homo sapiens_hsa04742 | 0.63890778 |
105 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.63391501 |
106 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.62413960 |
107 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.62345390 |
108 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61260176 |
109 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.60936556 |
110 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60366991 |
111 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.60020000 |
112 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58449589 |
113 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.57785114 |
114 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.57308341 |
115 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.57151680 |
116 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.56988571 |
117 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.55728057 |
118 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.54570208 |
119 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.54205473 |
120 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.54127531 |
121 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.53681218 |
122 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52412341 |
123 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.52057286 |
124 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51007948 |
125 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.50101871 |
126 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.48668575 |
127 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.47857289 |
128 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47503707 |
129 | Carbon metabolism_Homo sapiens_hsa01200 | 0.46963118 |
130 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.46844428 |
131 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.46143477 |
132 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.45422531 |
133 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.44953164 |
134 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.43691638 |
135 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43578912 |
136 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.43326742 |
137 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.42452998 |
138 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.40894122 |
139 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.39442503 |
140 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.38696237 |