EMILIN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1anatomical structure regression (GO:0060033)6.27245999
2positive regulation of male gonad development (GO:2000020)5.79959609
3protein heterotrimerization (GO:0070208)5.69897869
4sex determination (GO:0007530)5.48286721
5regulation of male gonad development (GO:2000018)5.16158620
6planar cell polarity pathway involved in neural tube closure (GO:0090179)4.86196532
7somite development (GO:0061053)4.70422751
8cell proliferation involved in metanephros development (GO:0072203)4.65277422
9regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.56660170
10bone trabecula formation (GO:0060346)4.40808973
11embryonic foregut morphogenesis (GO:0048617)4.31603868
12G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071994.27003648
13head development (GO:0060322)4.22241353
14midgut development (GO:0007494)4.16950736
15sex differentiation (GO:0007548)4.12421659
16male genitalia development (GO:0030539)4.04112594
17axon extension involved in axon guidance (GO:0048846)4.00952377
18neuron projection extension involved in neuron projection guidance (GO:1902284)4.00952377
19regulation of gonadotropin secretion (GO:0032276)3.94440637
20generation of neurons (GO:0048699)3.90569750
21lateral sprouting from an epithelium (GO:0060601)3.89885089
22positive regulation of gastrulation (GO:2000543)3.86233728
23tongue development (GO:0043586)3.86098836
24urogenital system development (GO:0001655)3.83860556
25outer ear morphogenesis (GO:0042473)3.73853771
26mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.71458377
27cranial nerve morphogenesis (GO:0021602)3.70581109
28organ induction (GO:0001759)3.66528095
29peripheral nervous system neuron development (GO:0048935)3.61592387
30polarized epithelial cell differentiation (GO:0030859)3.60619603
31paraxial mesoderm development (GO:0048339)3.57598805
32glomerular basement membrane development (GO:0032836)3.57557180
33Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.52362669
34regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.51253118
35positive regulation of hormone biosynthetic process (GO:0046886)3.50392524
36hindlimb morphogenesis (GO:0035137)3.44909271
37mesenchyme development (GO:0060485)3.44029869
38collagen fibril organization (GO:0030199)3.43515720
39positive regulation of chondrocyte differentiation (GO:0032332)3.43456728
40proximal/distal pattern formation (GO:0009954)3.42137178
41establishment of apical/basal cell polarity (GO:0035089)3.41895450
42regulation of establishment of planar polarity (GO:0090175)3.40202877
43atrial septum morphogenesis (GO:0060413)3.39122529
44segment specification (GO:0007379)3.37820844
45collagen catabolic process (GO:0030574)3.36632620
46collagen metabolic process (GO:0032963)3.36261868
47cell proliferation involved in kidney development (GO:0072111)3.35092835
48lung-associated mesenchyme development (GO:0060484)3.34848538
49muscle cell fate commitment (GO:0042693)3.34006959
50mesenchyme morphogenesis (GO:0072132)3.31856634
51epithelial cell fate commitment (GO:0072148)3.31097963
52convergent extension (GO:0060026)3.27839261
53cochlea morphogenesis (GO:0090103)3.27110455
54regulation of cardioblast proliferation (GO:0003264)3.26413096
55regulation of secondary heart field cardioblast proliferation (GO:0003266)3.26413096
56Leydig cell differentiation (GO:0033327)3.26262963
57myoblast migration (GO:0051451)3.24529557
58establishment of monopolar cell polarity (GO:0061162)3.23259094
59establishment or maintenance of monopolar cell polarity (GO:0061339)3.23259094
60endocardial cushion development (GO:0003197)3.22827279
61prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060523.22751459
62adrenal gland development (GO:0030325)3.21923343
63negative regulation of chondrocyte differentiation (GO:0032331)3.21307500
64mesenchymal cell proliferation (GO:0010463)3.20758284
65glomerular filtration (GO:0003094)3.16729092
66embryonic skeletal joint morphogenesis (GO:0060272)3.16210718
67male sex determination (GO:0030238)3.16107044
68non-canonical Wnt signaling pathway (GO:0035567)3.15888816
69embryonic camera-type eye development (GO:0031076)3.15437217
70multicellular organismal macromolecule metabolic process (GO:0044259)3.15182426
71androgen biosynthetic process (GO:0006702)3.14494164
72dorsal/ventral axis specification (GO:0009950)3.14059466
73embryonic hindlimb morphogenesis (GO:0035116)3.13903821
74endocardial cushion morphogenesis (GO:0003203)3.13107084
75negative regulation of axon extension involved in axon guidance (GO:0048843)3.11356151
76body morphogenesis (GO:0010171)3.08664351
77multicellular organismal catabolic process (GO:0044243)3.06756540
78eye morphogenesis (GO:0048592)3.06539534
79hippo signaling (GO:0035329)3.04879704
80embryonic eye morphogenesis (GO:0048048)3.03741316
81negative regulation of cartilage development (GO:0061037)3.03061266
82reproductive system development (GO:0061458)3.02432202
83metanephric mesenchyme development (GO:0072075)3.01630083
84ribosomal small subunit biogenesis (GO:0042274)3.01323770
85gastrulation with mouth forming second (GO:0001702)3.01282639
86regulation of heart morphogenesis (GO:2000826)2.98367835
87genitalia development (GO:0048806)2.93785197
88embryonic skeletal system morphogenesis (GO:0048704)2.93599631
89multicellular organismal metabolic process (GO:0044236)2.93322129
90negative regulation of T cell differentiation in thymus (GO:0033085)2.93304259
91establishment of planar polarity (GO:0001736)2.93261263
92establishment of tissue polarity (GO:0007164)2.93261263
93middle ear morphogenesis (GO:0042474)2.92513320
94renal system development (GO:0072001)2.92334537
95aorta morphogenesis (GO:0035909)2.91578977
96oocyte development (GO:0048599)2.87156650
97mesenchymal to epithelial transition (GO:0060231)2.85841198
98forelimb morphogenesis (GO:0035136)2.85036421
99cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.84637951
100chondrocyte proliferation (GO:0035988)2.84095976
101basement membrane organization (GO:0071711)2.83355697
102regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.83246903
103face development (GO:0060324)2.82474937
104kidney mesenchyme development (GO:0072074)2.79499911
105regulation of transforming growth factor beta2 production (GO:0032909)2.79297540
106renal filtration (GO:0097205)2.79207293
107sequestering of extracellular ligand from receptor (GO:0035581)2.78930949
108negative regulation of fatty acid transport (GO:2000192)2.78900006
109positive regulation of cartilage development (GO:0061036)2.78412127
110negative regulation of axon guidance (GO:1902668)2.76010487
111embryonic skeletal system development (GO:0048706)2.75787238
112negative regulation of catenin import into nucleus (GO:0035414)2.75149574
113mesonephros development (GO:0001823)2.75108115
114lymph vessel development (GO:0001945)2.73242666
115morphogenesis of an epithelial fold (GO:0060571)2.72622297
116positive regulation of smoothened signaling pathway (GO:0045880)2.71653141
117embryonic organ morphogenesis (GO:0048562)2.71411607
118establishment of nucleus localization (GO:0040023)2.70994488
119regulation of organ formation (GO:0003156)2.68588563
120branching involved in ureteric bud morphogenesis (GO:0001658)2.68464559
121negative regulation of embryonic development (GO:0045992)2.68192540
122negative regulation of DNA repair (GO:0045738)2.67995569
123developmental induction (GO:0031128)2.67899609
124regulation of non-canonical Wnt signaling pathway (GO:2000050)2.67838810
125dorsal/ventral neural tube patterning (GO:0021904)2.65937630
126skeletal muscle organ development (GO:0060538)2.65439449
127regulation of cardioblast differentiation (GO:0051890)2.65364295
128heart valve formation (GO:0003188)2.65144676
129viral transcription (GO:0019083)2.64283660
130embryonic digestive tract morphogenesis (GO:0048557)2.62671761
131craniofacial suture morphogenesis (GO:0097094)2.62212423
132embryonic camera-type eye morphogenesis (GO:0048596)2.61758936
133cardiac muscle tissue development (GO:0048738)2.61265162
134cell-cell signaling involved in cell fate commitment (GO:0045168)2.59793910
135outflow tract septum morphogenesis (GO:0003148)2.59517659
136embryonic forelimb morphogenesis (GO:0035115)2.59253540
137neuron fate specification (GO:0048665)2.56807523
138camera-type eye morphogenesis (GO:0048593)2.54235808
139notochord development (GO:0030903)2.53381632
140positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)2.53326686
141positive regulation of mesenchymal cell proliferation (GO:0002053)2.52685363
142translational termination (GO:0006415)2.51697887
143embryonic digestive tract development (GO:0048566)2.50307844
144epithelial cell-cell adhesion (GO:0090136)2.49803357
145atrioventricular valve morphogenesis (GO:0003181)2.49098331
146positive regulation of embryonic development (GO:0040019)2.48345392
147cellular response to gonadotropin stimulus (GO:0071371)2.48259987
148skeletal system morphogenesis (GO:0048705)2.47198224
149diaphragm development (GO:0060539)2.46590818
150cardiac muscle adaptation (GO:0014887)2.43910860
151cardiac muscle hypertrophy in response to stress (GO:0014898)2.43910860
152muscle hypertrophy in response to stress (GO:0003299)2.43910860
153regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.42702856
154regulation of hair follicle development (GO:0051797)2.41700472
155neurogenesis (GO:0022008)2.40860670
156nephron tubule formation (GO:0072079)2.39063399
157positive regulation of neuroblast proliferation (GO:0002052)2.36484875
158cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.36250841
159gonadal mesoderm development (GO:0007506)14.9136032

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_21828071_ChIP-Seq_BEAS2B_Human4.45759794
2ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.93398803
3WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.73792268
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.63018253
5TP63_17297297_ChIP-ChIP_HaCaT_Human2.61648742
6EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.61499845
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.55901646
8ZFP281_18757296_ChIP-ChIP_E14_Mouse2.46174632
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.37200940
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.32633015
11E2F7_22180533_ChIP-Seq_HELA_Human2.32312660
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.28854436
13DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.27532238
14* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.20174535
15* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.20174535
16CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.15156240
17ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.10516112
18ZFP281_27345836_Chip-Seq_ESCs_Mouse2.09973376
19ISL1_27105846_Chip-Seq_CPCs_Mouse2.08487145
20EZH2_27304074_Chip-Seq_ESCs_Mouse2.06938147
21HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.05781661
22TRIM28_21343339_ChIP-Seq_HEK293_Human2.04998544
23TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.04154609
24KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.03896982
25KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.03896982
26KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.03896982
27RNF2_27304074_Chip-Seq_ESCs_Mouse1.96296852
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.94196196
29* EED_16625203_ChIP-ChIP_MESCs_Mouse1.93147485
30PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.90993064
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.84100273
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.79940870
33CLOCK_20551151_ChIP-Seq_293T_Human1.79791087
34* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.79716620
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.76103860
36* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.74801462
37* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.69983745
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.69351140
39TP53_20018659_ChIP-ChIP_R1E_Mouse1.69223438
40CTCF_27219007_Chip-Seq_Bcells_Human1.67765148
41AR_21909140_ChIP-Seq_LNCAP_Human1.66223820
42* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.65920658
43KDM2B_26808549_Chip-Seq_K562_Human1.65791209
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.65567959
45RING1B_27294783_Chip-Seq_NPCs_Mouse1.64822603
46NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.64815506
47PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.63425085
48TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.60691431
49* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.58988329
50SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.57459694
51SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.56015066
52XRN2_22483619_ChIP-Seq_HELA_Human1.55160266
53* SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.53913532
54SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.51757625
55MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.50566858
56POU5F1_16153702_ChIP-ChIP_HESCs_Human1.50506044
57* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.48781631
58ERG_21242973_ChIP-ChIP_JURKAT_Human1.46673267
59WT1_25993318_ChIP-Seq_PODOCYTE_Human1.43847379
60EP300_21415370_ChIP-Seq_HL-1_Mouse1.43397216
61POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.42446445
62ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.42019150
63ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.41908913
64RNF2_27304074_Chip-Seq_NSC_Mouse1.41404522
65RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.40370855
66EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40163854
67GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.39741021
68* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.38951045
69PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.38204509
70WT1_19549856_ChIP-ChIP_CCG9911_Human1.38167039
71* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.36768678
72MYC_18555785_ChIP-Seq_MESCs_Mouse1.34769852
73TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34385042
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.34313585
75KDM2B_26808549_Chip-Seq_DND41_Human1.34239449
76NFIB_24661679_ChIP-Seq_LUNG_Mouse1.32883393
77* LXR_22292898_ChIP-Seq_THP-1_Human1.31307878
78STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.30364890
79EGR1_19374776_ChIP-ChIP_THP-1_Human1.30002641
80RING1B_27294783_Chip-Seq_ESCs_Mouse1.26911651
81* SA1_27219007_Chip-Seq_ERYTHROID_Human1.25413869
82KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25063130
83KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.24624177
84RARG_19884340_ChIP-ChIP_MEFs_Mouse1.22814689
85TP53_22127205_ChIP-Seq_IMR90_Human1.20101193
86* EZH2_27294783_Chip-Seq_ESCs_Mouse1.19788674
87TCF3_18692474_ChIP-Seq_MEFs_Mouse1.17891958
88KDM2B_26808549_Chip-Seq_JURKAT_Human1.17040172
89P300_27058665_Chip-Seq_ZR-75-30cells_Human1.15669745
90TBX3_20139965_ChIP-Seq_ESCs_Mouse1.15049765
91TET1_21451524_ChIP-Seq_MESCs_Mouse1.14920007
92DROSHA_22980978_ChIP-Seq_HELA_Human1.13827184
93TBX3_20139965_ChIP-Seq_MESCs_Mouse1.13697675
94ELK3_25401928_ChIP-Seq_HUVEC_Human1.13503881
95CREB1_26743006_Chip-Seq_LNCaP_Human1.13417754
96THAP11_20581084_ChIP-Seq_MESCs_Mouse1.13032905
97* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.12817894
98BRD4_25478319_ChIP-Seq_HGPS_Human1.10919226
99TCF7_22412390_ChIP-Seq_EML_Mouse1.10413010
100* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.10272361
101TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.09451168
102* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.08903624
103* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.08301425
104SOX2_16153702_ChIP-ChIP_HESCs_Human1.08040802
105MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.05722295
106P68_20966046_ChIP-Seq_HELA_Human1.05600461
107CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04888885
108DNAJC2_21179169_ChIP-ChIP_NT2_Human1.04362060
109* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.04310765
110MYC_22102868_ChIP-Seq_BL_Human1.01480543
111* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01383644
112* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.00855170
113SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.00786310
114TTF2_22483619_ChIP-Seq_HELA_Human0.99378481
115POU5F1_16518401_ChIP-PET_MESCs_Mouse0.98626506
116MYC_19079543_ChIP-ChIP_MESCs_Mouse0.98008369
117ESR1_15608294_ChIP-ChIP_MCF-7_Human0.97590939
118DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.97245988
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.97006984
120RACK7_27058665_Chip-Seq_MCF-7_Human0.96943765
121FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.96275263
122SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95860046
123RUNX1_27514584_Chip-Seq_MCF-7_Human0.95727753
124KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.95396843
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.94581817
126HIF1A_21447827_ChIP-Seq_MCF-7_Human0.94349427
127ESR1_21235772_ChIP-Seq_MCF-7_Human0.94227559
128SMC4_20622854_ChIP-Seq_HELA_Human0.92758344
129CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92287889
130ZNF274_21170338_ChIP-Seq_K562_Hela0.91590651
131EZH2_22144423_ChIP-Seq_EOC_Human0.91185418
132MYC_18358816_ChIP-ChIP_MESCs_Mouse0.90064084
133CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.88919280
134BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.88881335
135FOXP1_21924763_ChIP-Seq_HESCs_Human0.88734289
136MYC_27129775_Chip-Seq_CORNEA_Mouse0.88159030
137SOX3_22085726_ChIP-Seq_NPCs_Mouse0.86384400
138NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.86017159
139SMC3_22415368_ChIP-Seq_MEFs_Mouse0.85292205
140CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84893750
141* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.83755678
142MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.82767630
143SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.82638975
144NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.82547708

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005503_abnormal_tendon_morphology3.55453609
2MP0008438_abnormal_cutaneous_collagen3.52699399
3MP0003122_maternal_imprinting3.47699648
4MP0010030_abnormal_orbit_morphology3.41049971
5MP0009053_abnormal_anal_canal3.25415024
6MP0003123_paternal_imprinting3.13249104
7MP0006292_abnormal_olfactory_placode3.08053226
8MP0004272_abnormal_basement_membrane2.59973889
9MP0005623_abnormal_meninges_morphology2.56219759
10MP0008789_abnormal_olfactory_epithelium2.40613795
11MP0003942_abnormal_urinary_system2.40517147
12MP0000537_abnormal_urethra_morphology2.37484486
13MP0001346_abnormal_lacrimal_gland2.36993054
14MP0008995_early_reproductive_senescence2.28295199
15MP0003283_abnormal_digestive_organ2.27818754
16MP0001958_emphysema2.27058654
17MP0003385_abnormal_body_wall2.25545485
18MP0003115_abnormal_respiratory_system2.23629072
19MP0009379_abnormal_foot_pigmentation2.19783592
20MP0000049_abnormal_middle_ear2.13916453
21MP0006054_spinal_hemorrhage2.09994464
22MP0000534_abnormal_ureter_morphology2.07054991
23MP0003121_genomic_imprinting2.04666638
24MP0003705_abnormal_hypodermis_morpholog1.98780717
25MP0000428_abnormal_craniofacial_morphol1.97254161
26MP0002282_abnormal_trachea_morphology1.93316698
27MP0002249_abnormal_larynx_morphology1.93271184
28MP0005248_abnormal_Harderian_gland1.88288202
29MP0002938_white_spotting1.88174153
30MP0005275_abnormal_skin_tensile1.87925026
31MP0003941_abnormal_skin_development1.87018793
32MP0004858_abnormal_nervous_system1.83555797
33MP0005377_hearing/vestibular/ear_phenot1.79776237
34MP0003878_abnormal_ear_physiology1.79776237
35MP0003119_abnormal_digestive_system1.79055524
36MP0009384_cardiac_valve_regurgitation1.78716187
37MP0002932_abnormal_joint_morphology1.75885103
38MP0009250_abnormal_appendicular_skeleto1.74654682
39MP0000566_synostosis1.70196665
40MP0003315_abnormal_perineum_morphology1.68143692
41MP0005508_abnormal_skeleton_morphology1.60001920
42MP0004134_abnormal_chest_morphology1.57685329
43MP0005076_abnormal_cell_differentiation1.54872920
44MP0000569_abnormal_digit_pigmentation1.54266070
45MP0002233_abnormal_nose_morphology1.51886981
46MP0003935_abnormal_craniofacial_develop1.51723235
47MP0003136_yellow_coat_color1.51219827
48MP0005499_abnormal_olfactory_system1.50403373
49MP0005394_taste/olfaction_phenotype1.50403373
50MP0002697_abnormal_eye_size1.50121613
51MP0003755_abnormal_palate_morphology1.48549271
52MP0002116_abnormal_craniofacial_bone1.43073636
53MP0001293_anophthalmia1.41969163
54MP0005257_abnormal_intraocular_pressure1.41136909
55MP0002234_abnormal_pharynx_morphology1.38924264
56MP0002102_abnormal_ear_morphology1.38077556
57MP0003937_abnormal_limbs/digits/tail_de1.36724635
58MP0000733_abnormal_muscle_development1.36390096
59MP0002108_abnormal_muscle_morphology1.35947280
60MP0000762_abnormal_tongue_morphology1.26975429
61MP0004197_abnormal_fetal_growth/weight/1.24886952
62MP0002109_abnormal_limb_morphology1.24448597
63MP0002092_abnormal_eye_morphology1.23657904
64MP0009780_abnormal_chondrocyte_physiolo1.23474345
65MP0000678_abnormal_parathyroid_gland1.21644066
66MP0000462_abnormal_digestive_system1.21239396
67MP0002115_abnormal_skeleton_extremities1.16841813
68MP0008877_abnormal_DNA_methylation1.15737199
69MP0000432_abnormal_head_morphology1.15722335
70MP0000751_myopathy1.15436275
71MP0010368_abnormal_lymphatic_system1.15359745
72MP0003567_abnormal_fetal_cardiomyocyte1.13540607
73MP0000163_abnormal_cartilage_morphology1.10813854
74MP0001286_abnormal_eye_development1.10132712
75MP0001661_extended_life_span1.08939810
76MP0002896_abnormal_bone_mineralization1.08528132
77MP0005423_abnormal_somatic_nervous1.08315097
78MP0003879_abnormal_hair_cell1.06526763
79MP0001340_abnormal_eyelid_morphology1.04985485
80MP0002114_abnormal_axial_skeleton1.04823683
81MP0001177_atelectasis1.04262920
82MP0001849_ear_inflammation1.03046344
83MP0000631_abnormal_neuroendocrine_gland1.01706777
84MP0002111_abnormal_tail_morphology1.00193730
85MP0000383_abnormal_hair_follicle0.97685233
86MP0005187_abnormal_penis_morphology0.96323630
87MP0001299_abnormal_eye_distance/0.96090400
88MP0002085_abnormal_embryonic_tissue0.95853658
89MP0000467_abnormal_esophagus_morphology0.94657567
90MP0000026_abnormal_inner_ear0.93554529
91MP0003938_abnormal_ear_development0.93060163
92MP0004145_abnormal_muscle_electrophysio0.91080945
93MP0004133_heterotaxia0.91030013
94MP0000579_abnormal_nail_morphology0.90693571
95MP0002084_abnormal_developmental_patter0.90451281
96MP0009278_abnormal_bone_marrow0.89750611
97MP0001986_abnormal_taste_sensitivity0.89003351
98MP0002210_abnormal_sex_determination0.87016341
99MP0005391_vision/eye_phenotype0.86710679
100MP0004233_abnormal_muscle_weight0.86106848
101MP0000778_abnormal_nervous_system0.84899205
102MP0000767_abnormal_smooth_muscle0.84891413
103MP0005197_abnormal_uvea_morphology0.84587849
104MP0002113_abnormal_skeleton_development0.84474906
105MP0003936_abnormal_reproductive_system0.83012992
106MP0009703_decreased_birth_body0.82628279
107MP0002160_abnormal_reproductive_system0.81496780
108MP0000516_abnormal_urinary_system0.80708004
109MP0005367_renal/urinary_system_phenotyp0.80708004
110MP0010678_abnormal_skin_adnexa0.80115976
111MP0002184_abnormal_innervation0.79135297
112MP0001243_abnormal_dermal_layer0.78886845
113MP0000759_abnormal_skeletal_muscle0.78630767
114MP0001270_distended_abdomen0.77822669
115MP0003861_abnormal_nervous_system0.77460859
116MP0001145_abnormal_male_reproductive0.77413666
117MP0003279_aneurysm0.77033435
118MP0002089_abnormal_postnatal_growth/wei0.76072130
119MP0002177_abnormal_outer_ear0.75882914
120MP0000003_abnormal_adipose_tissue0.75111817
121MP0000013_abnormal_adipose_tissue0.74469425
122MP0005193_abnormal_anterior_eye0.74313005
123MP0003787_abnormal_imprinting0.73979587
124MP0000538_abnormal_urinary_bladder0.70596199
125MP0000613_abnormal_salivary_gland0.70436871
126MP0002653_abnormal_ependyma_morphology0.70071918
127MP0002081_perinatal_lethality0.69963300
128MP0003890_abnormal_embryonic-extraembry0.68779861
129MP0006072_abnormal_retinal_apoptosis0.67438897
130MP0001188_hyperpigmentation0.66028304

Predicted human phenotypes

RankGene SetZ-score
1Ankle contracture (HP:0006466)5.23522346
2Calcaneovalgus deformity (HP:0001848)5.14826928
3Abnormality of the phalanges of the hallux (HP:0010057)4.77860714
4Short 4th metacarpal (HP:0010044)4.69185031
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.69185031
6Protrusio acetabuli (HP:0003179)4.56186170
7Deformed tarsal bones (HP:0008119)4.44279884
8Renal duplication (HP:0000075)4.21811175
9Turricephaly (HP:0000262)3.88284888
10Abnormality of the 4th metacarpal (HP:0010012)3.86424706
11Gonadal dysgenesis (HP:0000133)3.78451570
12Follicular hyperkeratosis (HP:0007502)3.72913342
13Male infertility (HP:0003251)3.69112434
14Shallow orbits (HP:0000586)3.64303351
15Absent phalangeal crease (HP:0006109)3.61508136
16Type 1 muscle fiber predominance (HP:0003803)3.59873360
17Bladder diverticulum (HP:0000015)3.56992702
18Premature rupture of membranes (HP:0001788)3.51590970
19Abnormality of the calcaneus (HP:0008364)3.34437111
20Abnormality of the middle phalanges of the toes (HP:0010183)3.32131649
21Slender build (HP:0001533)3.15408502
22Aortic dissection (HP:0002647)2.95998663
23Renovascular hypertension (HP:0100817)2.93056007
24Broad metatarsal (HP:0001783)2.92312034
25Neonatal short-limb short stature (HP:0008921)2.89397105
26Distal arthrogryposis (HP:0005684)2.87619211
27Symphalangism affecting the phalanges of the hand (HP:0009773)2.84206249
28Abnormality of the aortic arch (HP:0012303)2.81691920
29Abnormal finger flexion creases (HP:0006143)2.79029951
30Trismus (HP:0000211)2.75620009
31Soft skin (HP:0000977)2.62006445
32Rib fusion (HP:0000902)2.60898215
33Supernumerary ribs (HP:0005815)2.60353126
34Abnormality of the parietal bone (HP:0002696)2.58165724
35Male pseudohermaphroditism (HP:0000037)2.55873269
36Atrophic scars (HP:0001075)2.52942080
37Abnormality of the 1st metacarpal (HP:0010009)2.52257558
38Short middle phalanx of the 5th finger (HP:0004220)2.52122026
39Abnormality of dentin (HP:0010299)2.45134661
40Cutaneous syndactyly (HP:0012725)2.44623875
41Short 5th finger (HP:0009237)2.43516080
42Testicular neoplasm (HP:0010788)2.43072417
43Abnormal sex determination (HP:0012244)2.42915990
44Sex reversal (HP:0012245)2.42915990
45Germ cell neoplasia (HP:0100728)2.42804823
46Mesomelia (HP:0003027)2.41697151
47High anterior hairline (HP:0009890)2.40088928
48Fragile skin (HP:0001030)2.39677590
49Midline defect of the nose (HP:0004122)2.38549340
50Ulnar bowing (HP:0003031)2.38394046
51Cerebral aneurysm (HP:0004944)2.38093458
52Wide anterior fontanel (HP:0000260)2.36874797
53Mitral valve prolapse (HP:0001634)2.35562722
54Hyperacusis (HP:0010780)2.34925641
55Deviation of the hallux (HP:0010051)2.33721965
56Broad toe (HP:0001837)2.32391913
57Rectal prolapse (HP:0002035)2.30850252
58Flat cornea (HP:0007720)2.29397732
59Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.28392171
60Round ear (HP:0100830)2.28320697
61Supernumerary bones of the axial skeleton (HP:0009144)2.26774536
62Hypoplastic heart (HP:0001961)2.26140183
63Coronal craniosynostosis (HP:0004440)2.26134295
64Hallux valgus (HP:0001822)2.25866276
65Epiphyseal dysplasia (HP:0002656)2.24967972
66Spinal rigidity (HP:0003306)2.23791894
67Hypoventilation (HP:0002791)2.23775984
68Hepatoblastoma (HP:0002884)2.23358269
69Annular pancreas (HP:0001734)2.23339343
70Cutaneous finger syndactyly (HP:0010554)2.22414237
71Cupped ribs (HP:0000887)2.21349229
72Preaxial foot polydactyly (HP:0001841)2.21300086
73Overriding aorta (HP:0002623)2.19276611
74Mildly elevated creatine phosphokinase (HP:0008180)2.18641509
75Joint laxity (HP:0001388)2.16748265
76Broad thumb (HP:0011304)2.15655522
77Morphological abnormality of the middle ear (HP:0008609)2.14731299
78Selective tooth agenesis (HP:0001592)2.14379642
79Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.13571565
80Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.13563827
81Abnormality of the proximal phalanges of the hand (HP:0009834)2.12912526
82Increased variability in muscle fiber diameter (HP:0003557)2.12643603
83Vitreoretinal degeneration (HP:0000655)2.12403948
84Patent foramen ovale (HP:0001655)2.11993861
85Transposition of the great arteries (HP:0001669)2.11962298
86Abnormal connection of the cardiac segments (HP:0011545)2.11962298
87Abnormal ventriculo-arterial connection (HP:0011563)2.11962298
88Bowel diverticulosis (HP:0005222)2.11630436
89Neoplasm of the heart (HP:0100544)2.11592072
90Hypoplastic ischia (HP:0003175)2.11105625
91Asymmetry of the thorax (HP:0001555)2.10266377
92Facial hemangioma (HP:0000329)2.09565445
93Elfin facies (HP:0004428)2.07177420
94Blue sclerae (HP:0000592)2.04278550
95Broad long bones (HP:0005622)2.04238670
96Mild short stature (HP:0003502)2.02674065
97Limb-girdle muscle weakness (HP:0003325)2.02669556
98Infantile muscular hypotonia (HP:0008947)2.02156501
99Sprengel anomaly (HP:0000912)2.01984075
100Abnormality of the 2nd finger (HP:0004100)2.00113418
101Inguinal hernia (HP:0000023)1.99222042
102Hypoplastic left heart (HP:0004383)1.98725046
103Narrow nasal bridge (HP:0000446)1.95592334
104Broad phalanges of the hand (HP:0009768)1.94522820
105Broad distal phalanx of finger (HP:0009836)1.94382605
106Abnormal number of incisors (HP:0011064)1.94134155
107Short hallux (HP:0010109)1.92918636
108Broad finger (HP:0001500)1.92432987
109Partial duplication of the phalanx of hand (HP:0009999)1.91966143
110Abnormality of the distal phalanx of the thumb (HP:0009617)1.91350688
111Atresia of the external auditory canal (HP:0000413)1.90818156
112Mitral regurgitation (HP:0001653)1.90259783
113Breech presentation (HP:0001623)1.89955509
114Down-sloping shoulders (HP:0200021)1.87840817
115Genu recurvatum (HP:0002816)1.87757909
116Aortic aneurysm (HP:0004942)1.87107480
117Protruding ear (HP:0000411)1.85433619
118Aplasia involving bones of the upper limbs (HP:0009823)1.84643450
119Aplasia of the phalanges of the hand (HP:0009802)1.84643450
120Aplasia involving bones of the extremities (HP:0009825)1.84643450
121Buphthalmos (HP:0000557)1.84597796
122Thin ribs (HP:0000883)1.84088196
123Diastasis recti (HP:0001540)1.83847394
124Congenital diaphragmatic hernia (HP:0000776)1.83002601
125Short middle phalanx of finger (HP:0005819)1.82804244
126Broad phalanx (HP:0006009)1.82716328
127Increased nuchal translucency (HP:0010880)1.82495489
128Osteoarthritis (HP:0002758)1.81746446
129Periauricular skin pits (HP:0100277)1.81158532
130Preauricular pit (HP:0004467)1.81158532
131Dilatation of the ascending aorta (HP:0005111)1.80894289
132Abnormality of the ischium (HP:0003174)1.79921488
133Rocker bottom foot (HP:0001838)1.79788225
134Abnormality of the diencephalon (HP:0010662)1.79448568
135Ulnar deviation of the wrist (HP:0003049)1.77198309
136Abnormality of skeletal muscle fiber size (HP:0012084)1.76507070
137Camptodactyly of toe (HP:0001836)1.76255256
138Trigonocephaly (HP:0000243)1.76029145
139Testicular atrophy (HP:0000029)1.74355086
140Insomnia (HP:0100785)1.74155264
141Lymphangioma (HP:0100764)1.73753254
142Gonadotropin excess (HP:0000837)1.73235222
143Narrow palate (HP:0000189)1.72744429
144Short phalanx of the thumb (HP:0009660)1.72167236
145Rectal fistula (HP:0100590)1.72080033
146Rectovaginal fistula (HP:0000143)1.72080033
147Partial duplication of thumb phalanx (HP:0009944)1.71938535
148Broad hallux (HP:0010055)1.71354810
149Hypoplastic labia majora (HP:0000059)1.71255072
150Broad palm (HP:0001169)1.71036933
151Arachnodactyly (HP:0001166)1.70917854
152Abnormality of the radial head (HP:0003995)1.70853739
153Metatarsus adductus (HP:0001840)1.70393673
154Microglossia (HP:0000171)1.69410263
155Hypoplasia of the radius (HP:0002984)1.69159677
156Lumbar hyperlordosis (HP:0002938)1.67827655
157Pterygium (HP:0001059)1.67484886
158Renal dysplasia (HP:0000110)1.66891674
159Aplasia/Hypoplasia of the hallux (HP:0008362)1.65832721
160Abnormality of carpal bone ossification (HP:0006257)1.62182814
161Aplasia/Hypoplasia of the sacrum (HP:0008517)1.61511631

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.55074144
2TRIB34.06120522
3LATS13.78963377
4PDGFRA3.50962432
5CDK122.97183792
6RIPK12.94737484
7TYRO32.93165283
8MAP3K102.77996282
9EPHB22.67661452
10ICK2.57852744
11MAPK152.52126060
12LATS22.29274054
13PKN22.24003078
14CDK72.10643993
15PTK62.09132275
16EEF2K1.96785503
17BRD41.81919459
18PRPF4B1.78157024
19SMG11.76900911
20STK31.62316537
21FGFR11.53407481
22TTN1.52243932
23CDC71.50948888
24MUSK1.50600393
25MAP4K21.47786322
26MKNK11.46200222
27PAK21.45061800
28VRK21.42785054
29PAK41.42502259
30PASK1.38918763
31PRKD21.35206556
32NEK21.28558690
33PRKD31.28140239
34FER1.27943376
35TLK11.25720246
36FGFR21.24699024
37WNK11.23695824
38TGFBR11.21976030
39CDK41.21885679
40SIK11.18132450
41PNCK1.16029650
42PDGFRB1.14769214
43TAF11.13354049
44MYLK1.11951702
45FGFR41.10272655
46MET1.10121519
47MTOR1.08855382
48BUB11.05195026
49CSNK1A1L1.05054924
50ERBB31.03953390
51CAMK1G1.03878254
52STK38L1.02413815
53CDK11A1.01253930
54DAPK21.01236704
55MAP2K21.00873961
56DYRK20.97306941
57ERBB20.97164885
58MKNK20.96715489
59PTK20.96154823
60NTRK20.95657984
61CDK150.95379125
62CAMK1D0.95073306
63TAOK20.93369045
64EPHA30.92258796
65CDK190.88525248
66CDK180.85363201
67RPS6KA50.83694396
68SRPK10.81998962
69PHKG20.81896166
70PHKG10.81896166
71DMPK0.81871995
72RPS6KC10.81200634
73RPS6KL10.81200634
74MAPKAPK50.81186466
75CDC42BPA0.79977249
76CDK90.79609300
77RPS6KA60.77188205
78TTK0.77155040
79NME10.76183623
80NTRK30.75007760
81AURKA0.73189870
82PAK60.72407307
83KSR10.72275158
84BMX0.68201141
85BRSK10.66405886
86MARK20.65726613
87LRRK20.65534289
88CHEK10.64299931
89CDK60.64205351
90CDK30.64180682
91STK160.63695239
92CHEK20.63472012
93MELK0.60933026
94WNK40.60872999
95FGFR30.60789359
96ILK0.59402350
97CDK140.59170402
98WEE10.59159594
99ROCK20.59133949
100TRPM70.58575461
101SGK4940.57972031
102SGK2230.57972031
103CDK80.57522105
104OBSCN0.55445327
105PTK2B0.55391357
106NLK0.54974320
107AKT20.54906744
108ERBB40.53952184
109MAP3K40.53860117
110DYRK30.53232811
111STK110.51721648
112MOS0.51616272
113BRSK20.51164393
114EPHA40.51012975
115CSNK1G10.50631000
116ROCK10.48795768
117MAPK10.48584267
118CDK10.48577906
119CDK20.48107560
120LMTK20.46235039
121RET0.46229063
122RPS6KB20.46045909
123SCYL20.45934368
124INSRR0.45705120
125ATM0.45616905
126ALK0.43789017
127NTRK10.43549775
128RPS6KA40.43418257
129ATR0.41398542
130CLK10.38033625
131CHUK0.37629610
132AKT10.37296660
133ERN10.37040931
134CSNK1G30.36325127
135CSNK1G20.36156301
136MAPK140.34361741
137PRKDC0.33996790
138GSK3B0.33861192
139RPS6KA20.32641291
140PLK30.31944710
141DYRK1B0.31930026
142PLK10.31703630
143MAPK80.31437953
144STK40.31101836
145PRKCH0.30921494
146SRC0.30586344
147CASK0.30531879
148MAP3K70.29310047
149CSNK1E0.29104888
150MAPK100.28817809
151PRKCI0.27738698

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052174.79980676
2Hedgehog signaling pathway_Homo sapiens_hsa043404.76070171
3ECM-receptor interaction_Homo sapiens_hsa045123.59859552
4Protein digestion and absorption_Homo sapiens_hsa049743.30423709
5Hippo signaling pathway_Homo sapiens_hsa043902.88822784
6Ribosome_Homo sapiens_hsa030102.71622052
7TGF-beta signaling pathway_Homo sapiens_hsa043502.41005834
8Focal adhesion_Homo sapiens_hsa045102.28809167
9Wnt signaling pathway_Homo sapiens_hsa043102.17263373
10Notch signaling pathway_Homo sapiens_hsa043302.13398524
11Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045502.08382357
12Axon guidance_Homo sapiens_hsa043602.00209366
13Proteoglycans in cancer_Homo sapiens_hsa052051.97668650
14Sulfur relay system_Homo sapiens_hsa041221.90145308
15Small cell lung cancer_Homo sapiens_hsa052221.84823872
16Lysine degradation_Homo sapiens_hsa003101.77581076
17Adherens junction_Homo sapiens_hsa045201.69942868
18Melanogenesis_Homo sapiens_hsa049161.66448095
19Amoebiasis_Homo sapiens_hsa051461.59291364
20mRNA surveillance pathway_Homo sapiens_hsa030151.58675853
21Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.55987625
22Cell cycle_Homo sapiens_hsa041101.48978369
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.45515575
24Pathways in cancer_Homo sapiens_hsa052001.44422324
25MicroRNAs in cancer_Homo sapiens_hsa052061.41947185
26Ovarian steroidogenesis_Homo sapiens_hsa049131.39625250
27Vitamin B6 metabolism_Homo sapiens_hsa007501.30183060
28HTLV-I infection_Homo sapiens_hsa051661.25599511
29Colorectal cancer_Homo sapiens_hsa052101.21347624
30Spliceosome_Homo sapiens_hsa030401.20322137
31PI3K-Akt signaling pathway_Homo sapiens_hsa041511.19750273
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19704982
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.18295573
34RNA polymerase_Homo sapiens_hsa030201.18175765
35Thyroid hormone signaling pathway_Homo sapiens_hsa049191.17988467
36AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.17960836
37One carbon pool by folate_Homo sapiens_hsa006701.17147740
38Oocyte meiosis_Homo sapiens_hsa041141.16439174
39RNA transport_Homo sapiens_hsa030131.13705594
40Prostate cancer_Homo sapiens_hsa052151.13522568
41Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.13431718
42Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.12462540
43Dorso-ventral axis formation_Homo sapiens_hsa043201.10472320
44Tight junction_Homo sapiens_hsa045301.09690961
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.09086165
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.08449311
47Viral myocarditis_Homo sapiens_hsa054161.07507272
48Homologous recombination_Homo sapiens_hsa034400.99005904
49Central carbon metabolism in cancer_Homo sapiens_hsa052300.98500300
50Endometrial cancer_Homo sapiens_hsa052130.98106696
51Arginine and proline metabolism_Homo sapiens_hsa003300.95608966
52Chronic myeloid leukemia_Homo sapiens_hsa052200.95393668
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94045310
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.93953210
55Dilated cardiomyopathy_Homo sapiens_hsa054140.92574767
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.89786081
572-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89435485
58Fatty acid elongation_Homo sapiens_hsa000620.88988584
59Aldosterone synthesis and secretion_Homo sapiens_hsa049250.81916240
60Folate biosynthesis_Homo sapiens_hsa007900.81541731
61Estrogen signaling pathway_Homo sapiens_hsa049150.81056547
62Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.75901981
63cAMP signaling pathway_Homo sapiens_hsa040240.75346924
64Renin-angiotensin system_Homo sapiens_hsa046140.74916462
65Cardiac muscle contraction_Homo sapiens_hsa042600.74873063
66Biosynthesis of amino acids_Homo sapiens_hsa012300.73436888
67Galactose metabolism_Homo sapiens_hsa000520.72759284
68Glioma_Homo sapiens_hsa052140.72121155
69Cocaine addiction_Homo sapiens_hsa050300.71962374
70mTOR signaling pathway_Homo sapiens_hsa041500.71665890
71Insulin resistance_Homo sapiens_hsa049310.70278439
72Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68204091
73Renin secretion_Homo sapiens_hsa049240.67855102
74Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.67523097
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.66611311
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66276316
77Gap junction_Homo sapiens_hsa045400.65673998
78Nucleotide excision repair_Homo sapiens_hsa034200.65311633
79Vitamin digestion and absorption_Homo sapiens_hsa049770.64603743
80Insulin secretion_Homo sapiens_hsa049110.64331207
81Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.64193527
82Toxoplasmosis_Homo sapiens_hsa051450.64139458
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64096773
84Rap1 signaling pathway_Homo sapiens_hsa040150.63974970
85Fatty acid metabolism_Homo sapiens_hsa012120.63423861
86Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63248300
87DNA replication_Homo sapiens_hsa030300.62808578
88Melanoma_Homo sapiens_hsa052180.62791613
89Regulation of actin cytoskeleton_Homo sapiens_hsa048100.62382622
90Base excision repair_Homo sapiens_hsa034100.60347167
91Pancreatic cancer_Homo sapiens_hsa052120.60281273
92Vascular smooth muscle contraction_Homo sapiens_hsa042700.60278805
93Amphetamine addiction_Homo sapiens_hsa050310.60073229
94Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.59339431
95Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.57915744
96Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57301860
97N-Glycan biosynthesis_Homo sapiens_hsa005100.57229946
98Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56684433
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56372081
100Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56206406
101Fatty acid degradation_Homo sapiens_hsa000710.54740194
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54577090
103Purine metabolism_Homo sapiens_hsa002300.53032206
104Basal transcription factors_Homo sapiens_hsa030220.52507053
105Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50999084
106Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49903874
107Renal cell carcinoma_Homo sapiens_hsa052110.49680620
108AMPK signaling pathway_Homo sapiens_hsa041520.47032251
109Cyanoamino acid metabolism_Homo sapiens_hsa004600.46764524
110Platelet activation_Homo sapiens_hsa046110.46252968
111Phospholipase D signaling pathway_Homo sapiens_hsa040720.46170096
112Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.45968882
113Bladder cancer_Homo sapiens_hsa052190.45821193
114Pentose phosphate pathway_Homo sapiens_hsa000300.45492389
115Non-small cell lung cancer_Homo sapiens_hsa052230.45379212
116Circadian entrainment_Homo sapiens_hsa047130.44407897
117Fanconi anemia pathway_Homo sapiens_hsa034600.44381633
118Inositol phosphate metabolism_Homo sapiens_hsa005620.43196094
119Thyroid hormone synthesis_Homo sapiens_hsa049180.42602335
120Calcium signaling pathway_Homo sapiens_hsa040200.42313103
121Leukocyte transendothelial migration_Homo sapiens_hsa046700.41441403
122Selenocompound metabolism_Homo sapiens_hsa004500.41262212
123Viral carcinogenesis_Homo sapiens_hsa052030.41146476
124Pyrimidine metabolism_Homo sapiens_hsa002400.41042518
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40544810
126Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.39943850
127Fatty acid biosynthesis_Homo sapiens_hsa000610.38589642
128Glucagon signaling pathway_Homo sapiens_hsa049220.38287706
129ErbB signaling pathway_Homo sapiens_hsa040120.36664787
130Thyroid cancer_Homo sapiens_hsa052160.36372002
131Mismatch repair_Homo sapiens_hsa034300.36233786
132Endocytosis_Homo sapiens_hsa041440.36064565
133Choline metabolism in cancer_Homo sapiens_hsa052310.35742192
134Oxytocin signaling pathway_Homo sapiens_hsa049210.33562571
135VEGF signaling pathway_Homo sapiens_hsa043700.33210572
136Alcoholism_Homo sapiens_hsa050340.31549843
137Type II diabetes mellitus_Homo sapiens_hsa049300.31336371
138Ras signaling pathway_Homo sapiens_hsa040140.30230452
139GnRH signaling pathway_Homo sapiens_hsa049120.30020919
140Insulin signaling pathway_Homo sapiens_hsa049100.29840577
141Prolactin signaling pathway_Homo sapiens_hsa049170.29419000

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