EMP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)6.13421245
2cartilage development involved in endochondral bone morphogenesis (GO:0060351)5.89245031
3keratan sulfate catabolic process (GO:0042340)5.50473898
4chondrocyte proliferation (GO:0035988)5.04577301
5chondrocyte development (GO:0002063)4.98753098
6hemidesmosome assembly (GO:0031581)4.97155299
7skin morphogenesis (GO:0043589)4.76629144
8endodermal cell differentiation (GO:0035987)4.71777253
9positive regulation of extracellular matrix organization (GO:1903055)4.54495961
10cell adhesion mediated by integrin (GO:0033627)4.48138293
11endothelial cell morphogenesis (GO:0001886)4.32264909
12cartilage condensation (GO:0001502)4.24775070
13cell aggregation (GO:0098743)4.24775070
14protein heterotrimerization (GO:0070208)4.23277148
15collagen metabolic process (GO:0032963)4.22625597
16collagen catabolic process (GO:0030574)4.17408814
17multicellular organismal macromolecule metabolic process (GO:0044259)4.00035673
18notochord development (GO:0030903)3.97345977
19barbed-end actin filament capping (GO:0051016)3.94645106
20multicellular organismal catabolic process (GO:0044243)3.89784002
21multicellular organismal metabolic process (GO:0044236)3.81599567
22extracellular matrix disassembly (GO:0022617)3.80800226
23regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.64272653
24low-density lipoprotein particle clearance (GO:0034383)3.58266430
25positive regulation of osteoblast proliferation (GO:0033690)3.51981052
26negative regulation of fatty acid transport (GO:2000192)3.48315023
27positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.46406689
28negative regulation of chondrocyte differentiation (GO:0032331)3.42458559
29mesodermal cell differentiation (GO:0048333)3.42458250
30positive regulation of endothelial cell apoptotic process (GO:2000353)3.41986221
31positive regulation of p38MAPK cascade (GO:1900745)3.38542630
32wound healing, spreading of epidermal cells (GO:0035313)3.37937039
33negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.33717361
34peptidyl-proline hydroxylation (GO:0019511)3.31616007
35regulation of membrane protein ectodomain proteolysis (GO:0051043)3.30169597
36negative regulation of nitric oxide biosynthetic process (GO:0045019)3.29797818
37desmosome organization (GO:0002934)3.27619850
38regulation of mononuclear cell migration (GO:0071675)3.27208059
39iron ion import (GO:0097286)3.26851813
40adhesion of symbiont to host cell (GO:0044650)3.26797428
41virion attachment to host cell (GO:0019062)3.26797428
42endothelium development (GO:0003158)3.25014340
43retina vasculature morphogenesis in camera-type eye (GO:0061299)3.20923475
44regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.19257290
45positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.15771784
46limb bud formation (GO:0060174)3.14811168
47embryonic skeletal joint morphogenesis (GO:0060272)3.14777057
48ovulation from ovarian follicle (GO:0001542)3.13967366
49hypotonic response (GO:0006971)3.13168796
50peptide cross-linking (GO:0018149)3.12373010
51epithelial cell-cell adhesion (GO:0090136)3.11883282
52plasma membrane repair (GO:0001778)3.11376673
53regulation of extracellular matrix disassembly (GO:0010715)3.09204484
54endochondral ossification (GO:0001958)3.08037178
55replacement ossification (GO:0036075)3.08037178
56stress fiber assembly (GO:0043149)3.06930217
57extracellular fibril organization (GO:0043206)3.06364903
58fibril organization (GO:0097435)3.05638452
59positive regulation of cartilage development (GO:0061036)3.05449831
60negative regulation of cartilage development (GO:0061037)3.03952466
61regulation of integrin-mediated signaling pathway (GO:2001044)3.03126750
62basement membrane organization (GO:0071711)3.02550224
63axon extension involved in axon guidance (GO:0048846)3.02351590
64neuron projection extension involved in neuron projection guidance (GO:1902284)3.02351590
65regulation of transforming growth factor beta1 production (GO:0032908)3.02190841
66extracellular matrix organization (GO:0030198)3.01658828
67extracellular structure organization (GO:0043062)3.00459829
68bone trabecula formation (GO:0060346)2.95879174
69apoptotic cell clearance (GO:0043277)2.95825903
70negative regulation of anoikis (GO:2000811)2.95478593
71cell-substrate junction assembly (GO:0007044)2.95427030
72regulation of cartilage development (GO:0061035)2.94442429
73cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.94271177
74vascular endothelial growth factor signaling pathway (GO:0038084)2.94166975
75endothelial cell chemotaxis (GO:0035767)2.93592203
76protein hydroxylation (GO:0018126)2.91776844
77cartilage development (GO:0051216)2.90985553
78sequestering of extracellular ligand from receptor (GO:0035581)2.88262363
79hippo signaling (GO:0035329)2.87900728
80regulation of chondrocyte differentiation (GO:0032330)2.85658508
81vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.84866832
82renal filtration (GO:0097205)2.84059433
83dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.83361846
84maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.83232585
85negative regulation of focal adhesion assembly (GO:0051895)2.82609500
86negative regulation of cell junction assembly (GO:1901889)2.82609500
87negative regulation of adherens junction organization (GO:1903392)2.82609500
88regulation of vitamin D biosynthetic process (GO:0060556)2.82341586
89protein localization to endosome (GO:0036010)2.80723096
90response to progesterone (GO:0032570)2.80058382
91adhesion of symbiont to host (GO:0044406)2.78986601
92cell migration involved in heart development (GO:0060973)2.77516019
93atrioventricular valve morphogenesis (GO:0003181)2.77336451
94substrate-dependent cell migration (GO:0006929)2.76273147
95cellular response to thyroid hormone stimulus (GO:0097067)2.76270230
96positive regulation of epithelial to mesenchymal transition (GO:0010718)2.76082399
97protein retention in ER lumen (GO:0006621)2.74746703
98membrane raft organization (GO:0031579)2.74154319
99surfactant homeostasis (GO:0043129)2.72788912
100chondroitin sulfate biosynthetic process (GO:0030206)2.70241391
101keratan sulfate biosynthetic process (GO:0018146)2.69535912
102positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.68419691
103blood vessel maturation (GO:0001955)2.68245538
104proteoglycan metabolic process (GO:0006029)2.68122447
105extracellular matrix assembly (GO:0085029)2.65942712
106wound healing, spreading of cells (GO:0044319)2.64559623
107keratinization (GO:0031424)2.64322717
108positive regulation of blood vessel endothelial cell migration (GO:0043536)2.64007586
109hyaluronan catabolic process (GO:0030214)2.63681667
110protein localization to cell surface (GO:0034394)2.63181443
111regulation of extracellular matrix organization (GO:1903053)2.62866411
112cell migration involved in sprouting angiogenesis (GO:0002042)2.62556131
113negative regulation of platelet activation (GO:0010544)2.60393172
114substrate adhesion-dependent cell spreading (GO:0034446)2.58934618
115platelet-derived growth factor receptor signaling pathway (GO:0048008)2.58314286
116pinocytosis (GO:0006907)2.57560779
117epithelial to mesenchymal transition (GO:0001837)2.56875060
118regulation of macrophage chemotaxis (GO:0010758)2.56264773
119smooth muscle tissue development (GO:0048745)2.56071767
120positive regulation of chondrocyte differentiation (GO:0032332)2.55389737
121response to laminar fluid shear stress (GO:0034616)2.55347132
122regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.55346216
123cellular response to vitamin (GO:0071295)2.53762410
124dermatan sulfate biosynthetic process (GO:0030208)2.52923415
125cellular response to vitamin D (GO:0071305)2.52701373
126endocardial cushion morphogenesis (GO:0003203)2.52529587
127regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.52195600
128regulation of anoikis (GO:2000209)2.50529049
129angiogenesis involved in wound healing (GO:0060055)2.50363798
130positive regulation of astrocyte differentiation (GO:0048711)2.49361787
131lymph vessel development (GO:0001945)2.48536889
132kidney mesenchyme development (GO:0072074)2.48263154
133glomerular filtration (GO:0003094)2.46800235
134glial cell migration (GO:0008347)2.46416771
135keratinocyte differentiation (GO:0030216)2.45643529
136negative regulation of smooth muscle cell migration (GO:0014912)2.45513496
137wound healing (GO:0042060)2.45437205
138cellular response to interferon-alpha (GO:0035457)2.45218911
139regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.44709175
140heart valve morphogenesis (GO:0003179)2.44678037
141UDP-N-acetylglucosamine metabolic process (GO:0006047)2.44435014
142metanephric mesenchyme development (GO:0072075)2.44103586
143negative regulation of blood vessel endothelial cell migration (GO:0043537)2.43975157
144mesenchymal-epithelial cell signaling (GO:0060638)2.43718674
145regulation of tight junction assembly (GO:2000810)2.43596541
146regulation of p38MAPK cascade (GO:1900744)2.43263011
147negative regulation of smooth muscle cell differentiation (GO:0051151)2.43201787
148regulation of plasminogen activation (GO:0010755)2.43034044
149positive regulation of receptor recycling (GO:0001921)2.41415999
150negative regulation of homotypic cell-cell adhesion (GO:0034111)2.40376396
151regulation of smooth muscle cell migration (GO:0014910)2.39722041
152positive regulation of odontogenesis (GO:0042482)2.37663428
153regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.36849077
154negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.36635863
155keratinocyte proliferation (GO:0043616)2.36374654
156regulation of early endosome to late endosome transport (GO:2000641)2.33650130

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.75460001
2TRIM28_21343339_ChIP-Seq_HEK293_Human6.55738653
3* RARG_19884340_ChIP-ChIP_MEFs_Mouse3.79895867
4TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.78818214
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.01019595
6* SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.90526091
7CLOCK_20551151_ChIP-Seq_293T_Human2.74475601
8HIF1A_21447827_ChIP-Seq_MCF-7_Human2.70747595
9ESR1_21235772_ChIP-Seq_MCF-7_Human2.70650686
10* CJUN_26792858_Chip-Seq_BT549_Human2.61428381
11* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.38980783
12PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.38931316
13RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.37007917
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.33647823
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.30714387
16* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.29856493
17* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.29856493
18* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.14325926
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.12865456
20* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.10391179
21ESR2_21235772_ChIP-Seq_MCF-7_Human2.07832557
22WT1_19549856_ChIP-ChIP_CCG9911_Human1.97514452
23* BRD4_25478319_ChIP-Seq_HGPS_Human1.96841545
24PPAR_26484153_Chip-Seq_NCI-H1993_Human1.96683987
25NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.91630422
26SOX2_20726797_ChIP-Seq_SW620_Human1.88611887
27FOXO3_23340844_ChIP-Seq_DLD1_Human1.87282103
28JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.79869557
29RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.75156126
30ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.73916008
31* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.72743849
32* SMAD_19615063_ChIP-ChIP_OVARY_Human1.72562624
33SOX9_24532713_ChIP-Seq_HFSC_Mouse1.72190419
34NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.67518624
35NRF2_20460467_ChIP-Seq_MEFs_Mouse1.67518624
36* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.66124675
37GATA2_21666600_ChIP-Seq_HMVEC_Human1.65653770
38KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.65193997
39* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.56217188
40TP53_18474530_ChIP-ChIP_U2OS_Human1.56152696
41* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.55179910
42ATF3_27146783_Chip-Seq_COLON_Human1.51494664
43ELK3_25401928_ChIP-Seq_HUVEC_Human1.50928558
44UBF1/2_26484160_Chip-Seq_HMECs_Human1.48905747
45SALL4_18804426_ChIP-ChIP_XEN_Mouse1.46777639
46EP300_21415370_ChIP-Seq_HL-1_Mouse1.45925528
47CDX2_20551321_ChIP-Seq_CACO-2_Human1.44636548
48CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43432471
49* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.41835054
50* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.40969287
51SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39326558
52AR_21572438_ChIP-Seq_LNCaP_Human1.38391471
53FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.34784506
54TP53_16413492_ChIP-PET_HCT116_Human1.32702690
55* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32482814
56THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.29488154
57* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.27427916
58* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.27063848
59STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.26698247
60IRF8_27001747_Chip-Seq_BMDM_Mouse1.25615596
61* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.24472118
62* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.24281270
63SMC1_22415368_ChIP-Seq_MEFs_Mouse1.19909768
64ESR1_20079471_ChIP-ChIP_T-47D_Human1.19505141
65TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18552225
66HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16318694
67* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.16165808
68TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16027428
69RACK7_27058665_Chip-Seq_MCF-7_Human1.13979600
70PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.12815701
71TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.12312996
72NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.11809765
73* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.11652242
74* KLF5_25053715_ChIP-Seq_YYC3_Human1.11211814
75VDR_24787735_ChIP-Seq_THP-1_Human1.08256434
76CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07878574
77GATA3_24758297_ChIP-Seq_MCF-7_Human1.07829765
78* TBX20_22080862_ChIP-Seq_HEART_Mouse1.07800192
79* TBX20_22328084_ChIP-Seq_HEART_Mouse1.07800192
80TCF4_18268006_ChIP-ChIP_LS174T_Human1.06949425
81STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.06685180
82TP63_23658742_ChIP-Seq_EP156T_Human1.06110786
83GATA4_25053715_ChIP-Seq_YYC3_Human1.04016063
84* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03889298
85AHR_22903824_ChIP-Seq_MCF-7_Human1.02778002
86TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.01447284
87NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.00603480
88RUNX1_27514584_Chip-Seq_MCF-7_Human0.99505997
89STAT6_21828071_ChIP-Seq_BEAS2B_Human0.99095385
90LXR_22158963_ChIP-Seq_LIVER_Mouse0.99024156
91KDM2B_26808549_Chip-Seq_K562_Human0.98813751
92ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.94562415
93TP53_22127205_ChIP-Seq_IMR90_Human0.92540831
94NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.92056701
95SALL1_21062744_ChIP-ChIP_HESCs_Human0.91578788
96* RXR_22108803_ChIP-Seq_LS180_Human0.91102079
97EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89643112
98FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.89380696
99FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.88967812
100ZNF263_19887448_ChIP-Seq_K562_Human0.88585109
101* MYB_21317192_ChIP-Seq_ERMYB_Mouse0.88331447
102GATA6_25053715_ChIP-Seq_YYC3_Human0.88301691
103RXR_22158963_ChIP-Seq_LIVER_Mouse0.87306925
104* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.86633640
105ELK1_22589737_ChIP-Seq_MCF10A_Human0.86550404
106NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86418260
107SOX2_27498859_Chip-Seq_STOMACH_Mouse0.85544740
108CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.85459484
109AR_21909140_ChIP-Seq_LNCAP_Human0.84583587
110SMC3_22415368_ChIP-Seq_MEFs_Mouse0.84357982
111LXR_22292898_ChIP-Seq_THP-1_Human0.84093025
112PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.82306555
113TP53_20018659_ChIP-ChIP_R1E_Mouse0.82149696
114SA1_22415368_ChIP-Seq_MEFs_Mouse0.81804092
115TP53_23651856_ChIP-Seq_MEFs_Mouse0.81327543
116NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.80493875
117* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.80015435
118CTNNB1_20460455_ChIP-Seq_HCT116_Human0.79500863
119KDM2B_26808549_Chip-Seq_SUP-B15_Human0.78840252
120PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.78404833
121ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.77065735
122* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.77029841

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.77797182
2MP0005275_abnormal_skin_tensile4.81299918
3MP0005503_abnormal_tendon_morphology4.20607360
4MP0003705_abnormal_hypodermis_morpholog3.99976703
5MP0004272_abnormal_basement_membrane2.75280789
6MP0010352_gastrointestinal_tract_polyps2.60771636
7MP0003566_abnormal_cell_adhesion2.55448650
8MP0002282_abnormal_trachea_morphology2.52085496
9MP0003279_aneurysm2.48782901
10MP0002933_joint_inflammation2.37174439
11MP0001958_emphysema2.27683422
12MP0002060_abnormal_skin_morphology2.26457040
13MP0004134_abnormal_chest_morphology2.22357402
14MP0005623_abnormal_meninges_morphology2.21419485
15MP0006054_spinal_hemorrhage2.20260018
16MP0009384_cardiac_valve_regurgitation2.09071154
17MP0005508_abnormal_skeleton_morphology2.07110843
18MP0003191_abnormal_cellular_cholesterol2.05861497
19MP0009250_abnormal_appendicular_skeleto2.04146703
20MP0005023_abnormal_wound_healing2.00364628
21MP0000163_abnormal_cartilage_morphology1.91848328
22MP0002896_abnormal_bone_mineralization1.89828870
23MP0009840_abnormal_foam_cell1.86836637
24MP0003091_abnormal_cell_migration1.84101114
25MP0002877_abnormal_melanocyte_morpholog1.78704020
26MP0005257_abnormal_intraocular_pressure1.75617975
27MP0010234_abnormal_vibrissa_follicle1.71395132
28MP0002115_abnormal_skeleton_extremities1.67143820
29MP0005595_abnormal_vascular_smooth1.61716477
30MP0005058_abnormal_lysosome_morphology1.60718996
31MP0005390_skeleton_phenotype1.60196336
32MP0001299_abnormal_eye_distance/1.51678780
33MP0000762_abnormal_tongue_morphology1.50453999
34MP0002113_abnormal_skeleton_development1.49594891
35MP0003724_increased_susceptibility_to1.49514326
36MP0001542_abnormal_bone_strength1.48338168
37MP0005076_abnormal_cell_differentiation1.47292842
38MP0010030_abnormal_orbit_morphology1.45142675
39MP0001533_abnormal_skeleton_physiology1.44624661
40MP0002796_impaired_skin_barrier1.44391751
41MP0001243_abnormal_dermal_layer1.41614363
42MP0004510_myositis1.40241805
43MP0003941_abnormal_skin_development1.36636169
44MP0000733_abnormal_muscle_development1.36597822
45MP0003283_abnormal_digestive_organ1.33122859
46MP0004947_skin_inflammation1.32111816
47MP0002108_abnormal_muscle_morphology1.31825007
48MP0009053_abnormal_anal_canal1.29635256
49MP0005165_increased_susceptibility_to1.28046859
50MP0008004_abnormal_stomach_pH1.24333677
51MP0003300_gastrointestinal_ulcer1.22773095
52MP0010368_abnormal_lymphatic_system1.22249102
53MP0003385_abnormal_body_wall1.21880193
54MP0003075_altered_response_to1.21311934
55MP0002089_abnormal_postnatal_growth/wei1.19767913
56MP0003045_fibrosis1.19598484
57MP0000767_abnormal_smooth_muscle1.17629667
58MP0003950_abnormal_plasma_membrane1.16457456
59MP0003795_abnormal_bone_structure1.15519417
60MP0003453_abnormal_keratinocyte_physiol1.14082770
61MP0001851_eye_inflammation1.13132140
62MP0005409_darkened_coat_color1.11277158
63MP0005171_absent_coat_pigmentation1.10770538
64MP0002998_abnormal_bone_remodeling1.10117095
65MP0001853_heart_inflammation1.09249673
66MP0002109_abnormal_limb_morphology1.09245792
67MP0000751_myopathy1.08439870
68MP0003755_abnormal_palate_morphology1.08312802
69MP0005501_abnormal_skin_physiology1.07960781
70MP0000537_abnormal_urethra_morphology1.07803251
71MP0009780_abnormal_chondrocyte_physiolo1.06677775
72MP0006082_CNS_inflammation1.06025329
73MP0001216_abnormal_epidermal_layer1.05211983
74MP0005375_adipose_tissue_phenotype1.04524545
75MP0000750_abnormal_muscle_regeneration1.04400906
76MP0001879_abnormal_lymphatic_vessel1.04298285
77MP0002332_abnormal_exercise_endurance1.04145262
78MP0000858_altered_metastatic_potential1.03614840
79MP0003448_altered_tumor_morphology1.03568304
80MP0000343_altered_response_to1.03565495
81MP0005670_abnormal_white_adipose1.02999549
82MP0002295_abnormal_pulmonary_circulatio1.02371390
83MP0005666_abnormal_adipose_tissue0.99305692
84MP0000249_abnormal_blood_vessel0.96823439
85MP0000432_abnormal_head_morphology0.96745061
86MP0005167_abnormal_blood-brain_barrier0.96735205
87MP0006138_congestive_heart_failure0.95608461
88MP0010771_integument_phenotype0.95466891
89MP0004185_abnormal_adipocyte_glucose0.95383974
90MP0000604_amyloidosis0.92233302
91MP0004883_abnormal_blood_vessel0.91373817
92MP0000003_abnormal_adipose_tissue0.88667443
93MP0010678_abnormal_skin_adnexa0.87816437
94MP0002168_other_aberrant_phenotype0.86714323
95MP0004858_abnormal_nervous_system0.86598356
96MP0005164_abnormal_response_to0.86301009
97MP0001849_ear_inflammation0.85882791
98MP0002098_abnormal_vibrissa_morphology0.85654950
99MP0005367_renal/urinary_system_phenotyp0.85551595
100MP0000516_abnormal_urinary_system0.85551595
101MP0000013_abnormal_adipose_tissue0.83840506
102MP0002111_abnormal_tail_morphology0.83151070
103MP0000383_abnormal_hair_follicle0.81486712
104MP0002133_abnormal_respiratory_system0.81293810
105MP0005388_respiratory_system_phenotype0.81293810
106MP0003935_abnormal_craniofacial_develop0.80983527
107MP0002932_abnormal_joint_morphology0.80918642
108MP0000377_abnormal_hair_follicle0.80908790
109MP0002116_abnormal_craniofacial_bone0.80794749
110MP0003303_peritoneal_inflammation0.79258503
111MP0002148_abnormal_hypersensitivity_rea0.78494105
112MP0000467_abnormal_esophagus_morphology0.77652979
113MP0005166_decreased_susceptibility_to0.77471533
114MP0003690_abnormal_glial_cell0.75827581
115MP0003937_abnormal_limbs/digits/tail_de0.75308482
116MP0000647_abnormal_sebaceous_gland0.75295754
117MP0000049_abnormal_middle_ear0.75112080
118MP0000428_abnormal_craniofacial_morphol0.75039425
119MP0002419_abnormal_innate_immunity0.73668239
120MP0002971_abnormal_brown_adipose0.73656118
121MP0003436_decreased_susceptibility_to0.73520321
122MP0000465_gastrointestinal_hemorrhage0.71892802
123MP0003828_pulmonary_edema0.71153375
124MP0005197_abnormal_uvea_morphology0.70816442
125MP0009278_abnormal_bone_marrow0.69376683
126MP0001614_abnormal_blood_vessel0.69299844
127MP0002128_abnormal_blood_circulation0.69159640
128MP0004084_abnormal_cardiac_muscle0.68335121
129MP0002925_abnormal_cardiovascular_devel0.67961157
130MP0002233_abnormal_nose_morphology0.67256216
131MP0004197_abnormal_fetal_growth/weight/0.66874918
132MP0004484_altered_response_of0.66197754
133MP0003942_abnormal_urinary_system0.65968561
134MP0009115_abnormal_fat_cell0.65463729
135MP0004782_abnormal_surfactant_physiolog0.64899237
136MP0000427_abnormal_hair_cycle0.63924386

Predicted human phenotypes

RankGene SetZ-score
1Epiphyseal dysplasia (HP:0002656)5.86956366
2Irregular epiphyses (HP:0010582)4.98293609
3Premature rupture of membranes (HP:0001788)4.79326000
4Cupped ribs (HP:0000887)4.78093717
5Hypoplastic ischia (HP:0003175)4.65901698
6Vitreoretinal degeneration (HP:0000655)4.60249879
7Protrusio acetabuli (HP:0003179)4.59801446
8Neonatal short-limb short stature (HP:0008921)4.42139306
9Flat acetabular roof (HP:0003180)4.18467220
10Abnormality of the ischium (HP:0003174)4.07627987
11Cervical subluxation (HP:0003308)4.05639284
12Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.80399268
13Abnormal tarsal ossification (HP:0008369)3.66048140
14Vascular tortuosity (HP:0004948)3.54088777
15Atrophic scars (HP:0001075)3.50484776
16Small epiphyses (HP:0010585)3.48950208
17Flat capital femoral epiphysis (HP:0003370)3.42547152
18Abnormality of liposaccharide metabolism (HP:0010968)3.40196794
19Abnormality of glycosphingolipid metabolism (HP:0004343)3.40196794
20Abnormality of glycolipid metabolism (HP:0010969)3.40196794
21Abnormal foot bone ossification (HP:0010675)3.23626601
22Osteoarthritis (HP:0002758)3.21289404
23Metaphyseal cupping (HP:0003021)3.16973130
24Arterial tortuosity (HP:0005116)3.13278772
25Abnormal vertebral ossification (HP:0100569)3.02152563
26Delayed epiphyseal ossification (HP:0002663)3.01424915
27Genu varum (HP:0002970)3.00566361
28Ankle contracture (HP:0006466)3.00169467
29Coxa vara (HP:0002812)2.93398074
30Mild short stature (HP:0003502)2.92686715
31Myocardial infarction (HP:0001658)2.90820583
32Follicular hyperkeratosis (HP:0007502)2.86733584
33Reduced subcutaneous adipose tissue (HP:0003758)2.81635968
34Flattened epiphyses (HP:0003071)2.81099930
35Aortic dissection (HP:0002647)2.80591486
36Spondylolisthesis (HP:0003302)2.80203581
37Increased connective tissue (HP:0009025)2.76081524
38Bladder diverticulum (HP:0000015)2.69568614
39Platyspondyly (HP:0000926)2.68270026
40Spinal cord compression (HP:0002176)2.66794759
41Axonal loss (HP:0003447)2.65743516
42Natal tooth (HP:0000695)2.63615818
43Thick nail (HP:0001805)2.62402329
44Thoracolumbar scoliosis (HP:0002944)2.60531962
45Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.57123860
46Abnormality of femoral epiphyses (HP:0006499)2.57123860
47Shallow orbits (HP:0000586)2.57027648
48Abnormality of carpal bone ossification (HP:0006257)2.56458097
49Soft skin (HP:0000977)2.54390818
50Spinal rigidity (HP:0003306)2.53206081
51Abnormality of the acetabulum (HP:0003170)2.53022497
52Genu recurvatum (HP:0002816)2.52651161
53Fragile skin (HP:0001030)2.52419347
54Aortic aneurysm (HP:0004942)2.48373746
55Beaking of vertebral bodies (HP:0004568)2.46988208
56Absent frontal sinuses (HP:0002688)2.45967948
57Distal lower limb amyotrophy (HP:0008944)2.45421450
58Distal lower limb muscle weakness (HP:0009053)2.44033583
59Abnormality of the vertebral endplates (HP:0005106)2.43900056
60Alopecia of scalp (HP:0002293)2.40428163
61Mesomelia (HP:0003027)2.40301190
62Ulnar bowing (HP:0003031)2.40215982
63Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.39213210
64Vertebral hypoplasia (HP:0008417)2.39213210
65Increased variability in muscle fiber diameter (HP:0003557)2.38248336
66Abnormality of the 2nd finger (HP:0004100)2.37656999
67Wormian bones (HP:0002645)2.37550418
68Neurofibrillary tangles (HP:0002185)2.33961915
69Radial bowing (HP:0002986)2.33195879
70Abnormality of the proximal phalanges of the hand (HP:0009834)2.32835724
71Mitral valve prolapse (HP:0001634)2.32602873
72Limited elbow extension (HP:0001377)2.32278892
73Abnormal ossification of hand bones (HP:0005921)2.32080591
74Dilatation of the ascending aorta (HP:0005111)2.29813329
75Abnormality of the phalanges of the 2nd finger (HP:0009541)2.27843795
76Stillbirth (HP:0003826)2.26930546
77Nuclear cataract (HP:0100018)2.26391224
78Elbow flexion contracture (HP:0002987)2.24846773
79Ovoid vertebral bodies (HP:0003300)2.24583500
80Hip contracture (HP:0003273)2.24358553
81Peritonitis (HP:0002586)2.23272718
82Interstitial pulmonary disease (HP:0006530)2.23116488
83Type 1 muscle fiber predominance (HP:0003803)2.21037493
84Osteolytic defects of the phalanges of the hand (HP:0009771)2.20982715
85Osteolytic defects of the hand bones (HP:0009699)2.20982715
86Dysostosis multiplex (HP:0000943)2.19589173
87Exostoses (HP:0100777)2.18551969
88Blue sclerae (HP:0000592)2.18428663
89Limited hip movement (HP:0008800)2.18364759
90Acanthosis nigricans (HP:0000956)2.18148836
91Abnormality of the epiphysis of the femoral head (HP:0010574)2.17964262
92Protuberant abdomen (HP:0001538)2.17430504
93Lumbar hyperlordosis (HP:0002938)2.16488495
94Hypoplasia of the iris (HP:0007676)2.15592632
95Systemic lupus erythematosus (HP:0002725)2.15231455
96Thin ribs (HP:0000883)2.13259373
97Irregular vertebral endplates (HP:0003301)2.11216447
98Abnormality of skeletal muscle fiber size (HP:0012084)2.11175040
99Tetraparesis (HP:0002273)2.11071153
100Metaphyseal dysplasia (HP:0100255)2.10693541
101Hypoplasia of the odontoid process (HP:0003311)2.09724154
102Slender build (HP:0001533)2.09384084
103Aneurysm (HP:0002617)2.08949939
104Abnormal hand bone ossification (HP:0010660)2.08232868
105Achilles tendon contracture (HP:0001771)2.07968947
106Tibial bowing (HP:0002982)2.07475366
107Mildly elevated creatine phosphokinase (HP:0008180)2.07384586
108Broad long bones (HP:0005622)2.07142500
109Mitral regurgitation (HP:0001653)2.06180493
110Vertebral clefting (HP:0008428)2.06056847
111Broad metatarsal (HP:0001783)2.05751102
112Vertebral compression fractures (HP:0002953)2.05617712
113Arthropathy (HP:0003040)2.04636348
114Cerebral aneurysm (HP:0004944)2.03533158
115Short nail (HP:0001799)2.02419257
116Absent epiphyses (HP:0010577)2.01904478
117Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.01904478
118Abnormality of the distal phalanges of the toes (HP:0010182)2.01263391
119Aortic regurgitation (HP:0001659)2.00970299
120Abnormality of complement system (HP:0005339)1.99396283
121Short femoral neck (HP:0100864)1.99359882
122Abnormality of dentin (HP:0010299)1.99253259
123Abnormality of the odontoid process (HP:0003310)1.98886007
124Mitral stenosis (HP:0001718)1.98014770
125Right ventricular cardiomyopathy (HP:0011663)1.97650166
126Metaphyseal irregularity (HP:0003025)1.96978414
127Enlarged epiphyses (HP:0010580)1.95635138
128Generalized amyotrophy (HP:0003700)1.95128537
129Abnormality of the pubic bones (HP:0003172)1.94690462
130Broad phalanx (HP:0006009)1.94487402
131Ectopia lentis (HP:0001083)1.94374482
132Abnormality of the femoral head (HP:0003368)1.94108744
133Milia (HP:0001056)1.94005200
134Overgrowth (HP:0001548)1.93902232
135Joint laxity (HP:0001388)1.93667859
136Joint stiffness (HP:0001387)1.91871615
137Cerebral inclusion bodies (HP:0100314)1.90118746
138Thin bony cortex (HP:0002753)1.89002785
139Lower limb amyotrophy (HP:0007210)1.88569760
140Pulmonary artery stenosis (HP:0004415)1.86542654
141Hyperextensible skin (HP:0000974)1.83956818
142Amyloidosis (HP:0011034)1.81270367
143Advanced eruption of teeth (HP:0006288)1.80972248
144Mucopolysacchariduria (HP:0008155)1.80964675
145Urinary glycosaminoglycan excretion (HP:0003541)1.80964675
146Segmental peripheral demyelination/remyelination (HP:0003481)1.78390553
147Abnormality of mucopolysaccharide metabolism (HP:0011020)1.77543375
148Abnormality of polysaccharide metabolism (HP:0011012)1.77543375
149Abnormality of glycosaminoglycan metabolism (HP:0004371)1.77543375
150Asymmetric septal hypertrophy (HP:0001670)1.77483145
151Cardiovascular calcification (HP:0011915)1.76354847
152Syringomyelia (HP:0003396)1.75624236
153Spinal cord lesions (HP:0100561)1.75624236
154Abnormality of the Achilles tendon (HP:0005109)1.74705685
155Hematochezia (HP:0002573)1.74426059
156Aortic valve stenosis (HP:0001650)1.70839100
157Onycholysis (HP:0001806)1.70661513
158Skin nodule (HP:0200036)1.70607375
159Increased IgE level (HP:0003212)1.69445816
160Abnormality of nail color (HP:0100643)1.66670543
161Plantar hyperkeratosis (HP:0007556)1.66603763
162Polycythemia (HP:0001901)1.64599015
163Broad face (HP:0000283)1.63093208
164Venous abnormality (HP:0002624)1.61707573
165Palmoplantar hyperkeratosis (HP:0000972)1.60856262
166Striae distensae (HP:0001065)1.60583353

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR25.19261354
2MAP3K34.25076789
3LATS13.35471005
4TTN3.22931247
5IRAK33.17112161
6EPHA23.14927428
7TRIB32.87578191
8TRPM72.29121522
9EPHB22.26305595
10STK38L2.19547840
11STK32.10442328
12PDGFRA2.01701135
13RIPK11.93989445
14MYLK1.93885178
15PRKG21.91387281
16MST1R1.86001079
17MST41.81645519
18STK241.79446396
19PKN21.76874542
20FER1.73893315
21FRK1.64511545
22SIK11.64016027
23MET1.61048798
24ERBB31.57502565
25LRRK21.54768269
26PTK61.52059243
27BMX1.48115843
28ERN11.47655190
29PAK21.47106102
30CDC42BPA1.45752160
31PIM21.43152721
32PTK21.43018640
33TGFBR21.40062687
34MAP3K61.36513726
35STK101.36344131
36LATS21.32169927
37PRPF4B1.29034465
38RPS6KA41.24706324
39NUAK11.23516852
40TESK11.23391262
41GRK71.22593632
42NTRK11.18426212
43DMPK1.15011323
44PAK41.12110393
45EPHB11.09516228
46MAPK71.07471347
47NEK91.07206936
48PDGFRB1.06344286
49MOS1.06093816
50PIK3CA1.04654857
51EPHA30.98889918
52CDK60.98415472
53MAP3K130.97272909
54NME20.95159445
55NME10.94032454
56TGFBR10.92446404
57ROCK10.91087154
58FGFR10.89587676
59EEF2K0.86239774
60GSK3A0.86045774
61FGFR30.83484221
62LIMK10.83302299
63ZAP700.79494810
64MAP3K10.78641285
65TAOK10.75905138
66ICK0.74884387
67MAP2K30.74801946
68TIE10.73854064
69STK380.71261939
70MAP3K20.70764837
71PDK20.70696873
72ARAF0.70327756
73CLK10.70322064
74MAP2K10.69631147
75WNK10.69191950
76MTOR0.66743828
77PTK2B0.64796645
78TYK20.63707233
79PAK30.63634511
80CSK0.59785301
81ILK0.58405593
82RPS6KA20.58187556
83PLK20.57480494
84IRAK10.53165715
85MAPK120.51825291
86INSR0.51646543
87AKT30.51075811
88MAPKAPK30.49775346
89MAPK40.48979807
90DYRK1B0.48161276
91JAK30.46526457
92KIT0.46345680
93ROCK20.45961439
94BMPR20.45934469
95PRKAA20.45356504
96FLT30.43387415
97JAK10.42399371
98MAP3K100.42203304
99ABL10.42142637
100CHUK0.41108663
101PRKD10.40872395
102CAMK1D0.40053167
103IKBKB0.39657155
104TBK10.39250610
105MAP3K140.39088894
106PRKD20.38529530
107KDR0.38235708
108FGFR40.38194607
109SGK30.38002302
110RPS6KB20.37946319
111PDPK10.37602824
112LMTK20.37333753
113CAMKK20.36350454
114BLK0.35346617
115MAP3K80.35124747
116MAP3K110.34964497
117KSR20.34681749
118EGFR0.34035765
119BRSK20.33587734
120MAP2K20.33211366
121MAPKAPK20.33114538
122ABL20.32830402
123SCYL20.32554996
124SRC0.32348746
125IGF1R0.31330463
126TAOK20.30864325
127CDK120.30060727
128RET0.29957570
129NLK0.28464926
130PRKD30.27567383
131PIK3CG0.26061128
132ERBB40.25509204

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045125.03908126
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.31721642
3Protein digestion and absorption_Homo sapiens_hsa049743.17475034
4Focal adhesion_Homo sapiens_hsa045103.04872290
5Proteoglycans in cancer_Homo sapiens_hsa052052.31833359
6Malaria_Homo sapiens_hsa051442.29904495
7Glycosaminoglycan degradation_Homo sapiens_hsa005312.21645851
8Adherens junction_Homo sapiens_hsa045202.20172458
9TGF-beta signaling pathway_Homo sapiens_hsa043502.06695958
10Small cell lung cancer_Homo sapiens_hsa052222.06362963
11Other glycan degradation_Homo sapiens_hsa005112.04499324
12Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.92716704
13Amoebiasis_Homo sapiens_hsa051461.90789760
14AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.83168660
15Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.81721182
16Bladder cancer_Homo sapiens_hsa052191.75708259
17Hippo signaling pathway_Homo sapiens_hsa043901.67145806
18PI3K-Akt signaling pathway_Homo sapiens_hsa041511.62863633
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.60012308
20MicroRNAs in cancer_Homo sapiens_hsa052061.59444413
21Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.52831689
22Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.46400992
23Prion diseases_Homo sapiens_hsa050201.45478607
24Leukocyte transendothelial migration_Homo sapiens_hsa046701.43228751
25Dilated cardiomyopathy_Homo sapiens_hsa054141.37291587
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.35459486
27Toxoplasmosis_Homo sapiens_hsa051451.29425081
28Chronic myeloid leukemia_Homo sapiens_hsa052201.29087706
29Complement and coagulation cascades_Homo sapiens_hsa046101.26011354
30Basal cell carcinoma_Homo sapiens_hsa052171.24877976
31Regulation of actin cytoskeleton_Homo sapiens_hsa048101.24407093
32Rheumatoid arthritis_Homo sapiens_hsa053231.24265149
33PPAR signaling pathway_Homo sapiens_hsa033201.24184149
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.19573444
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.15671916
36Sphingolipid metabolism_Homo sapiens_hsa006001.15098623
37Platelet activation_Homo sapiens_hsa046111.13784934
38Shigellosis_Homo sapiens_hsa051311.11774026
39TNF signaling pathway_Homo sapiens_hsa046681.10366856
40Tight junction_Homo sapiens_hsa045301.07824542
41Phagosome_Homo sapiens_hsa041451.05005431
42Viral myocarditis_Homo sapiens_hsa054161.04666862
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.02772096
44p53 signaling pathway_Homo sapiens_hsa041151.00523749
45Pancreatic cancer_Homo sapiens_hsa052120.98805239
46Staphylococcus aureus infection_Homo sapiens_hsa051500.95867406
47Melanoma_Homo sapiens_hsa052180.94738833
48Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94004420
49Apoptosis_Homo sapiens_hsa042100.92452981
50Pathways in cancer_Homo sapiens_hsa052000.92392992
51Thyroid cancer_Homo sapiens_hsa052160.91937525
52Hedgehog signaling pathway_Homo sapiens_hsa043400.91210262
53Renin-angiotensin system_Homo sapiens_hsa046140.90679555
54Salmonella infection_Homo sapiens_hsa051320.90124039
55Rap1 signaling pathway_Homo sapiens_hsa040150.89296193
56Prostate cancer_Homo sapiens_hsa052150.87933114
57Osteoclast differentiation_Homo sapiens_hsa043800.86897820
58African trypanosomiasis_Homo sapiens_hsa051430.86869677
59HIF-1 signaling pathway_Homo sapiens_hsa040660.86368973
60Leishmaniasis_Homo sapiens_hsa051400.85644451
61Mineral absorption_Homo sapiens_hsa049780.83248906
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.82764149
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.82565058
64Influenza A_Homo sapiens_hsa051640.80426583
65HTLV-I infection_Homo sapiens_hsa051660.79326572
66Legionellosis_Homo sapiens_hsa051340.79187433
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78175692
68Vibrio cholerae infection_Homo sapiens_hsa051100.74789393
69Renal cell carcinoma_Homo sapiens_hsa052110.74438450
70Hepatitis B_Homo sapiens_hsa051610.73488405
71Sulfur metabolism_Homo sapiens_hsa009200.72490654
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71116431
73Glioma_Homo sapiens_hsa052140.70052106
74GnRH signaling pathway_Homo sapiens_hsa049120.69668271
75VEGF signaling pathway_Homo sapiens_hsa043700.69122594
76Wnt signaling pathway_Homo sapiens_hsa043100.67319537
77Colorectal cancer_Homo sapiens_hsa052100.66856186
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.66531097
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.66477683
80Pertussis_Homo sapiens_hsa051330.66096857
81Axon guidance_Homo sapiens_hsa043600.63062919
82Hematopoietic cell lineage_Homo sapiens_hsa046400.61390214
83Endometrial cancer_Homo sapiens_hsa052130.61033966
84Ovarian steroidogenesis_Homo sapiens_hsa049130.60935080
85Circadian rhythm_Homo sapiens_hsa047100.60785491
86Viral carcinogenesis_Homo sapiens_hsa052030.59243483
87Prolactin signaling pathway_Homo sapiens_hsa049170.57607881
88Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.57154968
89Starch and sucrose metabolism_Homo sapiens_hsa005000.56591877
90mTOR signaling pathway_Homo sapiens_hsa041500.56259087
91RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.54211862
92Insulin resistance_Homo sapiens_hsa049310.52204703
93Vascular smooth muscle contraction_Homo sapiens_hsa042700.51382164
94Endocytosis_Homo sapiens_hsa041440.49975995
95Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.49645258
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.48213168
97Chemokine signaling pathway_Homo sapiens_hsa040620.48169088
98Tuberculosis_Homo sapiens_hsa051520.47599034
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.47531376
100Lysosome_Homo sapiens_hsa041420.47098495
101Ras signaling pathway_Homo sapiens_hsa040140.47090990
102Acute myeloid leukemia_Homo sapiens_hsa052210.46212595
103Melanogenesis_Homo sapiens_hsa049160.46125658
104Gap junction_Homo sapiens_hsa045400.45578354
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45563183
106Dorso-ventral axis formation_Homo sapiens_hsa043200.45544036
107Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45447340
108FoxO signaling pathway_Homo sapiens_hsa040680.44605710
109Toll-like receptor signaling pathway_Homo sapiens_hsa046200.44302497
110Notch signaling pathway_Homo sapiens_hsa043300.43617435
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43566954
112Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43080158
113NF-kappa B signaling pathway_Homo sapiens_hsa040640.42484517
114Estrogen signaling pathway_Homo sapiens_hsa049150.41748348
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.41553477
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.40199778
117Steroid biosynthesis_Homo sapiens_hsa001000.39349240
118Caffeine metabolism_Homo sapiens_hsa002320.38997650
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36610351
120Hepatitis C_Homo sapiens_hsa051600.35609864

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