EMSY

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine dimer repair (GO:0006290)4.92165421
2regulation of centriole replication (GO:0046599)4.63473280
3presynaptic membrane assembly (GO:0097105)4.41898123
4mitotic sister chromatid cohesion (GO:0007064)4.25547893
5postsynaptic membrane organization (GO:0001941)4.02464036
6neural tube formation (GO:0001841)3.92889415
7presynaptic membrane organization (GO:0097090)3.91993973
8microtubule anchoring (GO:0034453)3.77456904
9histone H3-K9 methylation (GO:0051567)3.71648260
10pre-miRNA processing (GO:0031054)3.47026430
11monoubiquitinated protein deubiquitination (GO:0035520)3.47019561
12neuron cell-cell adhesion (GO:0007158)3.45662670
13microtubule nucleation (GO:0007020)3.44645749
14sister chromatid segregation (GO:0000819)3.37234581
15regulation of centrosome duplication (GO:0010824)3.34523208
16intraciliary transport (GO:0042073)3.28814054
17negative regulation of DNA-dependent DNA replication (GO:2000104)3.28178689
18sister chromatid cohesion (GO:0007062)3.27390665
19histone H3-K9 modification (GO:0061647)3.24989438
20central nervous system myelination (GO:0022010)3.24903192
21axon ensheathment in central nervous system (GO:0032291)3.24903192
22replication fork processing (GO:0031297)3.24208179
23histone H3-K4 trimethylation (GO:0080182)3.21563177
24positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.19784850
25cytoplasmic mRNA processing body assembly (GO:0033962)3.17213931
26microtubule depolymerization (GO:0007019)3.15152336
27microtubule polymerization or depolymerization (GO:0031109)3.13943862
28nuclear pore complex assembly (GO:0051292)3.07459250
29regulation of centrosome cycle (GO:0046605)3.06986045
30resolution of meiotic recombination intermediates (GO:0000712)3.06845744
31regulation of RNA export from nucleus (GO:0046831)3.04952181
32regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.00551074
33regulation of mitotic spindle checkpoint (GO:1903504)3.00551074
34regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.99487691
35protein localization to synapse (GO:0035418)2.98881544
36ionotropic glutamate receptor signaling pathway (GO:0035235)2.98162555
37cranial nerve structural organization (GO:0021604)2.97455605
38histone lysine methylation (GO:0034968)2.97194070
39cerebral cortex radially oriented cell migration (GO:0021799)2.96823699
40mitotic sister chromatid segregation (GO:0000070)2.96664844
41histone H4-K16 acetylation (GO:0043984)2.96239728
42regulation of chromatin silencing (GO:0031935)2.94515892
43pyrimidine nucleobase catabolic process (GO:0006208)2.92994455
44cranial nerve morphogenesis (GO:0021602)2.90721155
45postreplication repair (GO:0006301)2.89520535
46facial nerve structural organization (GO:0021612)2.85687632
47glutamate receptor signaling pathway (GO:0007215)2.85266066
48central nervous system projection neuron axonogenesis (GO:0021952)2.82376840
49peptidyl-lysine methylation (GO:0018022)2.80520068
50regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.77849765
51positive regulation of dendritic spine morphogenesis (GO:0061003)2.76816986
52neuronal action potential propagation (GO:0019227)2.76613995
53attachment of spindle microtubules to kinetochore (GO:0008608)2.75737785
54meiotic chromosome segregation (GO:0045132)2.75721680
55microtubule organizing center organization (GO:0031023)2.75529551
56positive regulation by host of viral transcription (GO:0043923)2.75195920
57negative regulation of cytosolic calcium ion concentration (GO:0051481)2.74991913
58short-term memory (GO:0007614)2.74744980
59G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.73610999
60RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.73462255
61nerve growth factor signaling pathway (GO:0038180)2.73009003
62limb bud formation (GO:0060174)2.70288519
63nuclear pore organization (GO:0006999)2.70200246
64regulation of telomere maintenance (GO:0032204)2.66695819
65detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.66606323
66DNA topological change (GO:0006265)2.66500790
67regulation of pigment cell differentiation (GO:0050932)2.66468657
68snRNA processing (GO:0016180)2.62728929
69recombinational repair (GO:0000725)2.62498860
70DNA replication-dependent nucleosome organization (GO:0034723)2.62132129
71DNA replication-dependent nucleosome assembly (GO:0006335)2.62132129
72double-strand break repair via homologous recombination (GO:0000724)2.61785661
73behavioral response to ethanol (GO:0048149)2.61143677
74neuron recognition (GO:0008038)2.58989228
75radial glial cell differentiation (GO:0060019)2.58402167
76hindbrain development (GO:0030902)2.58310493
77centrosome organization (GO:0051297)2.57857346
78lymphoid progenitor cell differentiation (GO:0002320)2.57173288
79positive regulation of synapse assembly (GO:0051965)2.56890322
80melanin biosynthetic process (GO:0042438)2.54894412
81synapsis (GO:0007129)2.54463655
82positive regulation of megakaryocyte differentiation (GO:0045654)2.53780790
83maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.53712246
84secondary metabolite biosynthetic process (GO:0044550)2.53041331
85cilium morphogenesis (GO:0060271)2.52681598
86centrosome duplication (GO:0051298)2.52656468
87protein K11-linked deubiquitination (GO:0035871)2.52428130
88central nervous system neuron axonogenesis (GO:0021955)2.52389860
89DNA double-strand break processing (GO:0000729)2.52329470
90protein localization to cilium (GO:0061512)2.52288862
91regulation of gene silencing (GO:0060968)2.51618719
92artery development (GO:0060840)2.51171300
93histone methylation (GO:0016571)2.51136182
94regulation of histone H3-K9 methylation (GO:0051570)2.49470787
95positive regulation of dendritic spine development (GO:0060999)2.49216025
96regulation of nuclear cell cycle DNA replication (GO:0033262)2.49213397
97mechanosensory behavior (GO:0007638)2.48648832
98positive regulation of gene expression, epigenetic (GO:0045815)2.48597454
99regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.48585276
100phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.48034442
101melanin metabolic process (GO:0006582)2.47754308
102lateral sprouting from an epithelium (GO:0060601)2.46498404
103centriole replication (GO:0007099)2.46323836
104regulation of histone H3-K4 methylation (GO:0051569)2.45691927
105retinal cone cell development (GO:0046549)2.45130403
106regulation of timing of cell differentiation (GO:0048505)2.44954481
107negative regulation of translation, ncRNA-mediated (GO:0040033)2.44954091
108regulation of translation, ncRNA-mediated (GO:0045974)2.44954091
109negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.44954091
110negative regulation of organelle assembly (GO:1902116)2.44927472
111positive regulation of meiosis (GO:0045836)2.44394308
112startle response (GO:0001964)2.44358557
113dorsal/ventral axis specification (GO:0009950)2.44275630
114genitalia morphogenesis (GO:0035112)2.44119488
115positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.44078107
116positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.44078107
117positive regulation of mitotic sister chromatid separation (GO:1901970)2.44078107
118regulation of histone methylation (GO:0031060)2.43987454
119regulation of respiratory system process (GO:0044065)2.43622647
120negative regulation of histone methylation (GO:0031061)2.43507293
121cell proliferation in forebrain (GO:0021846)2.43462231
122positive regulation of developmental pigmentation (GO:0048087)2.43271031
123regulation of cilium movement (GO:0003352)2.42792754
124reciprocal meiotic recombination (GO:0007131)2.42226819
125reciprocal DNA recombination (GO:0035825)2.42226819
126cilium movement (GO:0003341)2.41450396
127DNA synthesis involved in DNA repair (GO:0000731)2.41338160
128regulation of DNA endoreduplication (GO:0032875)2.40434390
129righting reflex (GO:0060013)2.40419265
130interkinetic nuclear migration (GO:0022027)2.38741767
131regulation of glutamate receptor signaling pathway (GO:1900449)2.36541398
132neurotransmitter-gated ion channel clustering (GO:0072578)2.35289216
133gamma-aminobutyric acid signaling pathway (GO:0007214)2.35247624
134regulation of development, heterochronic (GO:0040034)2.35065709
135regulation of excitatory postsynaptic membrane potential (GO:0060079)2.34632609
136negative regulation of synaptic transmission, GABAergic (GO:0032229)2.34527233
137regulation of synapse assembly (GO:0051963)2.33956184
138forebrain neuron differentiation (GO:0021879)2.33631349
139specification of organ identity (GO:0010092)2.30387703
140sympathetic nervous system development (GO:0048485)2.29515558
141synaptic transmission, glutamatergic (GO:0035249)2.29355496
142axonal fasciculation (GO:0007413)2.28525352
143positive regulation of meiotic cell cycle (GO:0051446)2.28401328
144retina layer formation (GO:0010842)2.27850051
145DNA ligation (GO:0006266)2.27578325
146negative regulation of T-helper cell differentiation (GO:0045623)2.27046446
147negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.27046446
148regulation of respiratory gaseous exchange (GO:0043576)2.26245656
149nonmotile primary cilium assembly (GO:0035058)2.25408569
150head development (GO:0060322)2.25353515
151cerebellar Purkinje cell differentiation (GO:0021702)2.25056608
152vocalization behavior (GO:0071625)2.24670782
153developmental pigmentation (GO:0048066)2.23716109
154cilium or flagellum-dependent cell motility (GO:0001539)2.23602959
155centriole assembly (GO:0098534)2.23557051
156olfactory bulb development (GO:0021772)2.22730252
157auditory behavior (GO:0031223)2.22670698
158regulation of postsynaptic membrane potential (GO:0060078)2.22214917
159epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.19238056
160regulation of non-canonical Wnt signaling pathway (GO:2000050)2.17904460
161ventricular system development (GO:0021591)2.17634017
162mesenchymal cell differentiation involved in renal system development (GO:2001012)2.17299807
163mesenchymal cell differentiation involved in kidney development (GO:0072161)2.17299807
164regulation of rhodopsin mediated signaling pathway (GO:0022400)2.16913487
165rhodopsin mediated signaling pathway (GO:0016056)2.15981584
166anatomical structure arrangement (GO:0048532)2.15657321
167positive regulation of membrane potential (GO:0045838)2.15437697
168peptidyl-lysine trimethylation (GO:0018023)2.14638963
169mesonephros development (GO:0001823)2.14447634
170L-amino acid import (GO:0043092)2.14204667
171mRNA splice site selection (GO:0006376)2.12929294
172regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.12721262
173histone H3-K4 methylation (GO:0051568)2.12103967
174protein heterotetramerization (GO:0051290)2.11813436
175neuron-neuron synaptic transmission (GO:0007270)2.11522333
176epithelial cilium movement (GO:0003351)2.11436903
177axonemal dynein complex assembly (GO:0070286)2.11178368
178transmission of nerve impulse (GO:0019226)2.10603424
179regulation of dendritic spine development (GO:0060998)2.10063148
180cell morphogenesis involved in neuron differentiation (GO:0048667)2.09744207
181long-term memory (GO:0007616)2.09442637
182dendritic spine morphogenesis (GO:0060997)2.08337981
183regulation of memory T cell differentiation (GO:0043380)2.07705470
184photoreceptor cell differentiation (GO:0046530)2.07581248

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.88951550
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.14395901
3GBX2_23144817_ChIP-Seq_PC3_Human3.48541429
4E2F7_22180533_ChIP-Seq_HELA_Human3.23150230
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.89829217
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.77461924
7ZNF274_21170338_ChIP-Seq_K562_Hela2.65251623
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.56843990
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.53881290
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.41268420
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.26316905
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.24271192
13BMI1_23680149_ChIP-Seq_NPCS_Mouse2.23505930
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.22458368
15CBX2_27304074_Chip-Seq_ESCs_Mouse2.18568891
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.18066584
17RNF2_18974828_ChIP-Seq_MESCs_Mouse2.18066584
18SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.16730031
19KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.08461084
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06174418
21JARID2_20075857_ChIP-Seq_MESCs_Mouse2.01956163
22TAF15_26573619_Chip-Seq_HEK293_Human2.00589275
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.00201748
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97162493
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.90907878
26POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88762414
27RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.88732594
28RNF2_27304074_Chip-Seq_ESCs_Mouse1.88247446
29FUS_26573619_Chip-Seq_HEK293_Human1.86679596
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.85078066
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84738806
32RNF2_27304074_Chip-Seq_NSC_Mouse1.83561559
33SMAD_19615063_ChIP-ChIP_OVARY_Human1.82601276
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.82326653
35IRF1_19129219_ChIP-ChIP_H3396_Human1.77475485
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.76699907
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.74049221
38EZH2_27294783_Chip-Seq_ESCs_Mouse1.73750142
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71929041
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.71687986
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.71486755
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69342235
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.68236956
44IGF1R_20145208_ChIP-Seq_DFB_Human1.67407191
45TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.66176185
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.65571432
47PADI4_21655091_ChIP-ChIP_MCF-7_Human1.65258778
48AR_21572438_ChIP-Seq_LNCaP_Human1.65223984
49P300_19829295_ChIP-Seq_ESCs_Human1.63474579
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.62671607
51CTBP2_25329375_ChIP-Seq_LNCAP_Human1.61219661
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.59705744
53CBP_20019798_ChIP-Seq_JUKART_Human1.59705744
54TP63_19390658_ChIP-ChIP_HaCaT_Human1.59676135
55POU5F1_16153702_ChIP-ChIP_HESCs_Human1.56970247
56FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.55038447
57SMAD3_21741376_ChIP-Seq_EPCs_Human1.54181414
58MTF2_20144788_ChIP-Seq_MESCs_Mouse1.53568030
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.51723454
60NANOG_18555785_Chip-Seq_ESCs_Mouse1.51192218
61SMAD4_21799915_ChIP-Seq_A2780_Human1.50813037
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49479837
63PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42871206
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.42585370
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.41635113
66SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.40403406
67EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.40125373
68TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39719782
69POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39719782
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.39230158
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39062995
72BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.38641128
73E2F1_18555785_Chip-Seq_ESCs_Mouse1.38150482
74DROSHA_22980978_ChIP-Seq_HELA_Human1.36615727
75EWS_26573619_Chip-Seq_HEK293_Human1.34301462
76CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34100015
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.32635247
78ELK1_19687146_ChIP-ChIP_HELA_Human1.31879107
79REST_21632747_ChIP-Seq_MESCs_Mouse1.30120445
80P53_22387025_ChIP-Seq_ESCs_Mouse1.29570069
81E2F1_21310950_ChIP-Seq_MCF-7_Human1.29534737
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29386960
83SUZ12_18555785_Chip-Seq_ESCs_Mouse1.26617841
84NR3C1_21868756_ChIP-Seq_MCF10A_Human1.24562752
85CMYC_18555785_Chip-Seq_ESCs_Mouse1.24056825
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22954995
87EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.21813065
88P300_18555785_Chip-Seq_ESCs_Mouse1.21494821
89ER_23166858_ChIP-Seq_MCF-7_Human1.21207665
90RING1B_27294783_Chip-Seq_NPCs_Mouse1.20957786
91FLI1_21867929_ChIP-Seq_TH2_Mouse1.20673256
92STAT3_23295773_ChIP-Seq_U87_Human1.20522206
93SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.19310716
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.18938653
95OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18641907
96NOTCH1_21737748_ChIP-Seq_TLL_Human1.18599453
97TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17942671
98HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17473099
99MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.17209153
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.16686221
101SOX9_26525672_Chip-Seq_HEART_Mouse1.16549861
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15655659
103TCF4_23295773_ChIP-Seq_U87_Human1.15415075
104VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14364429
105FOXM1_26456572_ChIP-Seq_MCF-7_Human1.13325685
106TP53_16413492_ChIP-PET_HCT116_Human1.12304421
107AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11389993
108FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.11317149
109STAT3_18555785_Chip-Seq_ESCs_Mouse1.11287370
110CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.11201832
111NMYC_18555785_Chip-Seq_ESCs_Mouse1.10197850
112VDR_22108803_ChIP-Seq_LS180_Human1.09969086
113SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09965811
114IKZF1_21737484_ChIP-ChIP_HCT116_Human1.09871012
115SOX2_21211035_ChIP-Seq_LN229_Gbm1.09615213
116TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08855196
117RUNX2_22187159_ChIP-Seq_PCA_Human1.08013580
118TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07828010
119PKCTHETA_26484144_Chip-Seq_BREAST_Human1.07350114
120TCF4_18268006_ChIP-ChIP_LS174T_Human1.07041429
121SOX2_18555785_Chip-Seq_ESCs_Mouse1.06285764
122OCT4_18555785_Chip-Seq_ESCs_Mouse1.05334524
123STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.05124070
124LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05001792
125RUNX1_27457419_Chip-Seq_LIVER_Mouse1.04624879
126TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03538531
127CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03346127
128BCAT_22108803_ChIP-Seq_LS180_Human1.03294927
129TCF4_22108803_ChIP-Seq_LS180_Human1.02911647
130CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02531292
131RING1B_27294783_Chip-Seq_ESCs_Mouse1.02248093
132PRDM14_20953172_ChIP-Seq_ESCs_Human1.02102545
133P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01807621
134AR_25329375_ChIP-Seq_VCAP_Human1.01233839
135KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01060948
136MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99243343
137MYC_18940864_ChIP-ChIP_HL60_Human0.98962486
138UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98584411
139AHR_22903824_ChIP-Seq_MCF-7_Human0.98554514
140TP53_22573176_ChIP-Seq_HFKS_Human0.97781360
141TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97647382
142STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97336957
143ESR1_20079471_ChIP-ChIP_T-47D_Human0.97236559

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.48585297
2MP0003880_abnormal_central_pattern4.16338519
3MP0003136_yellow_coat_color3.51244105
4MP0005409_darkened_coat_color3.33124368
5MP0006292_abnormal_olfactory_placode3.27483135
6MP0001188_hyperpigmentation3.14037250
7MP0005187_abnormal_penis_morphology2.80391532
8MP0000566_synostosis2.35765947
9MP0003787_abnormal_imprinting2.29450982
10MP0004381_abnormal_hair_follicle2.08810454
11MP0002102_abnormal_ear_morphology2.05006249
12MP0004859_abnormal_synaptic_plasticity1.97532530
13MP0000778_abnormal_nervous_system1.90238189
14MP0001486_abnormal_startle_reflex1.89875496
15MP0005171_absent_coat_pigmentation1.89436657
16MP0004742_abnormal_vestibular_system1.86824879
17MP0005423_abnormal_somatic_nervous1.80033609
18MP0000049_abnormal_middle_ear1.78220099
19MP0005551_abnormal_eye_electrophysiolog1.75852512
20MP0005174_abnormal_tail_pigmentation1.74969894
21MP0003938_abnormal_ear_development1.72721407
22MP0003635_abnormal_synaptic_transmissio1.71800289
23MP0003890_abnormal_embryonic-extraembry1.69603683
24MP0006072_abnormal_retinal_apoptosis1.68975403
25MP0008877_abnormal_DNA_methylation1.66295734
26MP0000015_abnormal_ear_pigmentation1.65639132
27MP0000427_abnormal_hair_cycle1.62862611
28MP0002009_preneoplasia1.60383479
29MP0003077_abnormal_cell_cycle1.58767482
30MP0009745_abnormal_behavioral_response1.57011809
31MP0003943_abnormal_hepatobiliary_system1.55746529
32MP0005408_hypopigmentation1.51339956
33MP0005248_abnormal_Harderian_gland1.49269421
34MP0002736_abnormal_nociception_after1.48980832
35MP0009379_abnormal_foot_pigmentation1.47890393
36MP0004270_analgesia1.43834604
37MP0000631_abnormal_neuroendocrine_gland1.43118288
38MP0004145_abnormal_muscle_electrophysio1.42765378
39MP0002249_abnormal_larynx_morphology1.41506001
40MP0001324_abnormal_eye_pigmentation1.41431598
41MP0002272_abnormal_nervous_system1.40453759
42MP0001346_abnormal_lacrimal_gland1.37950942
43MP0002184_abnormal_innervation1.37906181
44MP0002067_abnormal_sensory_capabilities1.34943258
45MP0001968_abnormal_touch/_nociception1.34736781
46MP0000647_abnormal_sebaceous_gland1.30891983
47MP0001485_abnormal_pinna_reflex1.29441527
48MP0005075_abnormal_melanosome_morpholog1.28872514
49MP0009046_muscle_twitch1.28635487
50MP0002751_abnormal_autonomic_nervous1.28297314
51MP0003121_genomic_imprinting1.27725639
52MP0005253_abnormal_eye_physiology1.26894078
53MP0002572_abnormal_emotion/affect_behav1.26754695
54MP0000026_abnormal_inner_ear1.26478393
55MP0002064_seizures1.26110300
56MP0008932_abnormal_embryonic_tissue1.24782636
57MP0000569_abnormal_digit_pigmentation1.23097315
58MP0003111_abnormal_nucleus_morphology1.23012100
59MP0002557_abnormal_social/conspecific_i1.22494928
60MP0004133_heterotaxia1.22381655
61MP0001293_anophthalmia1.21171028
62MP0002177_abnormal_outer_ear1.20798976
63MP0003937_abnormal_limbs/digits/tail_de1.20385470
64MP0002752_abnormal_somatic_nervous1.15991647
65MP0002938_white_spotting1.15011908
66MP0003119_abnormal_digestive_system1.14148833
67MP0009703_decreased_birth_body1.14135680
68MP0002063_abnormal_learning/memory/cond1.13981284
69MP0008569_lethality_at_weaning1.13097149
70MP0008995_early_reproductive_senescence1.10044986
71MP0002396_abnormal_hematopoietic_system1.09874385
72MP0001963_abnormal_hearing_physiology1.09514677
73MP0002638_abnormal_pupillary_reflex1.09481642
74MP0001919_abnormal_reproductive_system1.09151561
75MP0002697_abnormal_eye_size1.07080895
76MP0002882_abnormal_neuron_morphology1.06612093
77MP0005646_abnormal_pituitary_gland1.04706772
78MP0003315_abnormal_perineum_morphology1.04616254
79MP0004885_abnormal_endolymph1.04037831
80MP0005386_behavior/neurological_phenoty1.02275920
81MP0004924_abnormal_behavior1.02275920
82MP0009250_abnormal_appendicular_skeleto1.02070918
83MP0004197_abnormal_fetal_growth/weight/1.00696110
84MP0002095_abnormal_skin_pigmentation1.00406325
85MP0004957_abnormal_blastocyst_morpholog1.00250695
86MP0002734_abnormal_mechanical_nocicepti1.00009665
87MP0006276_abnormal_autonomic_nervous0.99678412
88MP0003385_abnormal_body_wall0.98972862
89MP0005394_taste/olfaction_phenotype0.98489688
90MP0005499_abnormal_olfactory_system0.98489688
91MP0002277_abnormal_respiratory_mucosa0.97336448
92MP0008789_abnormal_olfactory_epithelium0.96299505
93MP0002084_abnormal_developmental_patter0.95251148
94MP0003861_abnormal_nervous_system0.94238941
95MP0004808_abnormal_hematopoietic_stem0.92354067
96MP0001929_abnormal_gametogenesis0.89600669
97MP0001697_abnormal_embryo_size0.89058421
98MP0000371_diluted_coat_color0.88865445
99MP0003122_maternal_imprinting0.88541749
100MP0004142_abnormal_muscle_tone0.88270706
101MP0004043_abnormal_pH_regulation0.88077643
102MP0003693_abnormal_embryo_hatching0.87859886
103MP0002152_abnormal_brain_morphology0.87635319
104MP0003755_abnormal_palate_morphology0.87237883
105MP0002233_abnormal_nose_morphology0.87107745
106MP0002735_abnormal_chemical_nociception0.85839822
107MP0005195_abnormal_posterior_eye0.85534883
108MP0003935_abnormal_craniofacial_develop0.85350838
109MP0002163_abnormal_gland_morphology0.85211831
110MP0005391_vision/eye_phenotype0.84925518
111MP0002116_abnormal_craniofacial_bone0.84813110
112MP0000955_abnormal_spinal_cord0.84750163
113MP0002928_abnormal_bile_duct0.84645246
114MP0003567_abnormal_fetal_cardiomyocyte0.83687595
115MP0002088_abnormal_embryonic_growth/wei0.83635518
116MP0005645_abnormal_hypothalamus_physiol0.83518839
117MP0005379_endocrine/exocrine_gland_phen0.82797935
118MP0001984_abnormal_olfaction0.82429948
119MP0003950_abnormal_plasma_membrane0.82279381
120MP0003984_embryonic_growth_retardation0.82158142
121MP0000383_abnormal_hair_follicle0.81355155
122MP0000653_abnormal_sex_gland0.79185898
123MP0005076_abnormal_cell_differentiation0.78388613
124MP0002822_catalepsy0.78006437
125MP0001672_abnormal_embryogenesis/_devel0.77856823
126MP0005380_embryogenesis_phenotype0.77856823
127MP0002085_abnormal_embryonic_tissue0.77847536
128MP0005647_abnormal_sex_gland0.77306038
129MP0003646_muscle_fatigue0.77041106
130MP0003878_abnormal_ear_physiology0.75591462
131MP0005377_hearing/vestibular/ear_phenot0.75591462
132MP0001986_abnormal_taste_sensitivity0.75555021
133MP0002210_abnormal_sex_determination0.75554669
134MP0008007_abnormal_cellular_replicative0.75536847
135MP0003763_abnormal_thymus_physiology0.74590718
136MP0001502_abnormal_circadian_rhythm0.74550059
137MP0001286_abnormal_eye_development0.74518658
138MP0001501_abnormal_sleep_pattern0.73918259
139MP0000432_abnormal_head_morphology0.72939053
140MP0001970_abnormal_pain_threshold0.69843794
141MP0010030_abnormal_orbit_morphology0.68354501
142MP0001440_abnormal_grooming_behavior0.67727014
143MP0010094_abnormal_chromosome_stability0.66747450
144MP0005623_abnormal_meninges_morphology0.66691054
145MP0008058_abnormal_DNA_repair0.66455886
146MP0001905_abnormal_dopamine_level0.65543415
147MP0001529_abnormal_vocalization0.64782089
148MP0002081_perinatal_lethality0.64731938
149MP0000372_irregular_coat_pigmentation0.64439491
150MP0003698_abnormal_male_reproductive0.63717253

Predicted human phenotypes

RankGene SetZ-score
1Peripheral hypomyelination (HP:0007182)3.55596828
2Focal motor seizures (HP:0011153)3.55155561
3Pancreatic cysts (HP:0001737)3.02321388
4Ulnar claw (HP:0001178)2.99104074
5Abnormality of chromosome stability (HP:0003220)2.93633950
6Abnormal ciliary motility (HP:0012262)2.91518313
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.88626100
8Dynein arm defect of respiratory motile cilia (HP:0012255)2.78693594
9Absent/shortened dynein arms (HP:0200106)2.78693594
10Febrile seizures (HP:0002373)2.77954817
11Genetic anticipation (HP:0003743)2.73729577
12Broad-based gait (HP:0002136)2.72424494
13Chromosomal breakage induced by crosslinking agents (HP:0003221)2.71209738
14Abnormal respiratory motile cilium physiology (HP:0012261)2.65836355
15Aplasia/Hypoplasia of the sternum (HP:0006714)2.64035199
16Intestinal atresia (HP:0011100)2.60611563
17Aqueductal stenosis (HP:0002410)2.59582762
18Chromsome breakage (HP:0040012)2.58982667
19Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.56996356
20Congenital stationary night blindness (HP:0007642)2.53155028
21Astigmatism (HP:0000483)2.49535579
22Abnormal respiratory motile cilium morphology (HP:0005938)2.46415695
23Abnormal respiratory epithelium morphology (HP:0012253)2.46415695
24Abnormality of the renal cortex (HP:0011035)2.40438173
25Supernumerary spleens (HP:0009799)2.39697202
26Progressive inability to walk (HP:0002505)2.38432039
27Fibular hypoplasia (HP:0003038)2.33953316
28Chronic hepatic failure (HP:0100626)2.33105820
29Sloping forehead (HP:0000340)2.31362182
30Abnormal lung lobation (HP:0002101)2.26885241
31Attenuation of retinal blood vessels (HP:0007843)2.26654699
32Abnormality of the carotid arteries (HP:0005344)2.25748572
33Medial flaring of the eyebrow (HP:0010747)2.24114500
34Aplasia/Hypoplasia of the tibia (HP:0005772)2.22732578
35Epileptic encephalopathy (HP:0200134)2.21993386
36Gaze-evoked nystagmus (HP:0000640)2.21818790
37Nonprogressive disorder (HP:0003680)2.21008164
38Aplasia/Hypoplasia of the tongue (HP:0010295)2.20226130
39Volvulus (HP:0002580)2.20189101
40Increased nuchal translucency (HP:0010880)2.20120647
41Decreased central vision (HP:0007663)2.19933450
42Congenital primary aphakia (HP:0007707)2.19920644
43Nephrogenic diabetes insipidus (HP:0009806)2.19406745
44Gait imbalance (HP:0002141)2.17144988
45Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15320082
46Poikiloderma (HP:0001029)2.15132873
47Duodenal stenosis (HP:0100867)2.13002955
48Small intestinal stenosis (HP:0012848)2.13002955
49Postaxial foot polydactyly (HP:0001830)2.12586686
50Sex reversal (HP:0012245)2.11188307
51Abnormal sex determination (HP:0012244)2.11188307
52Poor coordination (HP:0002370)2.09531597
53Thyroid-stimulating hormone excess (HP:0002925)2.09519895
54Genital tract atresia (HP:0001827)2.08446842
55Abnormality of the preputium (HP:0100587)2.08421430
56Supernumerary ribs (HP:0005815)2.08167193
57Vaginal atresia (HP:0000148)2.08102919
58Supernumerary bones of the axial skeleton (HP:0009144)2.06070982
59Tubular atrophy (HP:0000092)2.05595973
60Absent speech (HP:0001344)2.05308798
61Abnormal auditory evoked potentials (HP:0006958)2.04628994
62Midline defect of the nose (HP:0004122)2.04296401
63Megalencephaly (HP:0001355)2.04117823
64Ectopic kidney (HP:0000086)2.03381612
65Long clavicles (HP:0000890)2.02885131
66Abnormality of the axillary hair (HP:0100134)1.99895921
67Abnormality of secondary sexual hair (HP:0009888)1.99895921
68Septo-optic dysplasia (HP:0100842)1.99060103
69Abnormal hair whorl (HP:0010721)1.97441023
70Anophthalmia (HP:0000528)1.96543317
71Cutaneous melanoma (HP:0012056)1.94737358
72True hermaphroditism (HP:0010459)1.94720250
73Clubbing of toes (HP:0100760)1.93492297
74Absent septum pellucidum (HP:0001331)1.93282625
75Hypoplastic ischia (HP:0003175)1.92234357
76Nephronophthisis (HP:0000090)1.91397885
77Progressive cerebellar ataxia (HP:0002073)1.90171611
78Chin dimple (HP:0010751)1.89330924
79Abnormality of the septum pellucidum (HP:0007375)1.89249796
80Drooling (HP:0002307)1.88397441
81Excessive salivation (HP:0003781)1.88397441
82Steppage gait (HP:0003376)1.87519571
83Duplicated collecting system (HP:0000081)1.87156133
84Abnormality of the ischium (HP:0003174)1.86959519
85Aplasia/Hypoplasia of the fibula (HP:0006492)1.86856729
86Blue irides (HP:0000635)1.85259252
87Abnormality of the fingertips (HP:0001211)1.84210409
88Hyperventilation (HP:0002883)1.83286152
89Fair hair (HP:0002286)1.82744165
90Abnormality of the nasal septum (HP:0000419)1.82705735
91Anal stenosis (HP:0002025)1.82437461
92Abnormality of the left ventricular outflow tract (HP:0011103)1.81449705
93Subaortic stenosis (HP:0001682)1.81449705
94Optic nerve hypoplasia (HP:0000609)1.81072915
95Congenital sensorineural hearing impairment (HP:0008527)1.80976987
96Abnormality of the renal collecting system (HP:0004742)1.80651492
97Bilateral microphthalmos (HP:0007633)1.80485165
98Tubulointerstitial abnormality (HP:0001969)1.80275835
99Absent radius (HP:0003974)1.79925632
100Abnormality of the duodenum (HP:0002246)1.78451453
101Postaxial hand polydactyly (HP:0001162)1.78130675
102Cystic liver disease (HP:0006706)1.77914586
103Duplication of thumb phalanx (HP:0009942)1.77884725
104Wide intermamillary distance (HP:0006610)1.77871202
105Truncal obesity (HP:0001956)1.77484962
106Adrenal hypoplasia (HP:0000835)1.75850068
107Abnormal rod and cone electroretinograms (HP:0008323)1.75525709
108Severe visual impairment (HP:0001141)1.75163932
109Abnormality of chromosome segregation (HP:0002916)1.75156652
110Abnormality of the phalanges of the hallux (HP:0010057)1.73911347
111Dyschromatopsia (HP:0007641)1.73046282
112Oligodactyly (hands) (HP:0001180)1.73021159
113Enlarged kidneys (HP:0000105)1.72880754
114Focal seizures (HP:0007359)1.72829196
115Astrocytoma (HP:0009592)1.72678196
116Abnormality of the astrocytes (HP:0100707)1.72678196
117Highly arched eyebrow (HP:0002553)1.72365441
118Widely spaced teeth (HP:0000687)1.72361617
119Hypopigmentation of the fundus (HP:0007894)1.72211316
120Absent forearm bone (HP:0003953)1.72015794
121Aplasia involving forearm bones (HP:0009822)1.72015794
122Myelodysplasia (HP:0002863)1.71657289
123Abnormality of the parietal bone (HP:0002696)1.71119576
124Tubulointerstitial fibrosis (HP:0005576)1.70827760
125Small hand (HP:0200055)1.70673631
126Short foot (HP:0001773)1.70592250
127Inability to walk (HP:0002540)1.70575856
128Increased corneal curvature (HP:0100692)1.70252825
129Keratoconus (HP:0000563)1.70252825
130Short tibia (HP:0005736)1.68765292
131Abnormality of the labia minora (HP:0012880)1.68721728
132Nephroblastoma (Wilms tumor) (HP:0002667)1.68597635
133Cupped ear (HP:0000378)1.68143843
134Arthropathy (HP:0003040)1.67566320
135Alacrima (HP:0000522)1.67560880
136Glioma (HP:0009733)1.67556549
137Papillary thyroid carcinoma (HP:0002895)1.67079327
138Protruding tongue (HP:0010808)1.66670600
1392-3 toe syndactyly (HP:0004691)1.65254808
140Atonic seizures (HP:0010819)1.65237453
141Abnormality of the renal medulla (HP:0100957)1.64848227
142Rhinitis (HP:0012384)1.61748914
143Preaxial hand polydactyly (HP:0001177)1.61574725
144Cutaneous finger syndactyly (HP:0010554)1.61429461
145Trigonocephaly (HP:0000243)1.61335585
146Atelectasis (HP:0100750)1.61236151
147Oligodactyly (HP:0012165)1.59890871
148Anencephaly (HP:0002323)1.59865464
149Tented upper lip vermilion (HP:0010804)1.59795740
150Aplasia/Hypoplasia of the uvula (HP:0010293)1.58417757
151Decreased lacrimation (HP:0000633)1.57768752
152Molar tooth sign on MRI (HP:0002419)1.57498469
153Abnormality of midbrain morphology (HP:0002418)1.57498469
154Renal agenesis (HP:0000104)1.57121875
155Concave nail (HP:0001598)1.56915941
156Abnormality of the columella (HP:0009929)1.56915332
157Embryonal renal neoplasm (HP:0011794)1.56331269
158Obstructive sleep apnea (HP:0002870)1.56317167
159Meckel diverticulum (HP:0002245)1.56023038
160Tubulointerstitial nephritis (HP:0001970)1.55523906
161Bony spicule pigmentary retinopathy (HP:0007737)1.55329162
162Abnormality of incisor morphology (HP:0011063)1.54031744
163Abnormality of the incisor (HP:0000676)1.53483261
164Acute lymphatic leukemia (HP:0006721)1.53192020
165Male pseudohermaphroditism (HP:0000037)1.51914187
166Lip pit (HP:0100267)1.51725776
167Median cleft lip (HP:0000161)1.51536789
168Pancreatic fibrosis (HP:0100732)1.49884456
169Abnormality of the ileum (HP:0001549)1.49601430
170Abnormality of DNA repair (HP:0003254)1.49157385
171Hemiparesis (HP:0001269)1.48996580

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK6.38956140
2TNIK4.28137817
3FRK3.84761891
4MKNK23.21800453
5PLK43.17467483
6MUSK3.08108720
7WEE12.55630785
8WNK32.43151618
9BRSK22.37290954
10LATS12.37106819
11EPHA42.33850628
12MKNK12.19838656
13PNCK2.16775290
14TLK11.95342679
15BRD41.92214625
16SRPK11.86868409
17FES1.70577621
18NTRK31.69500489
19TRIM281.63467200
20MAP2K71.61035357
21FGFR21.58104020
22MAPK131.50656054
23CDK31.48121872
24WNK41.47705063
25DYRK31.47289732
26NUAK11.41282410
27CAMK1G1.40717369
28CDK121.38381683
29TXK1.36012793
30GRK11.35117769
31SIK21.32698343
32YES11.27611513
33EIF2AK11.23860581
34MAP3K101.21695947
35CLK11.19748953
36ERBB31.18272701
37NEK61.17310067
38PRKD21.14595543
39PRPF4B1.12953784
40NLK1.12588441
41STK391.11373458
42WNK11.10966085
43NEK21.09963291
44NTRK21.07814702
45STK38L1.05983762
46CAMK11.04426188
47PKN11.01453066
48MARK30.99398727
49STK30.98842713
50MAP4K20.97043627
51SIK30.94718297
52CDC70.94574974
53CDK90.92802000
54PLK30.92654391
55UHMK10.92185780
56RIPK40.89968523
57CSNK1A1L0.88175744
58CDK190.87900262
59MAP3K40.87699185
60OXSR10.86133840
61IRAK20.86016958
62CSNK1G10.84828822
63BMPR20.81858664
64FGR0.81844483
65DMPK0.81137449
66SGK30.80967394
67INSRR0.78678620
68ADRBK20.77309585
69BRSK10.76714011
70STK110.75563337
71FER0.73793001
72GRK70.71684219
73ACVR1B0.70492103
74HIPK20.70426922
75CAMK2B0.70036564
76CDK60.70018636
77CHEK20.69987758
78PLK10.68017479
79EIF2AK30.67014849
80CAMK2A0.66879432
81MARK20.66538881
82CAMK1D0.66229939
83MARK10.65664502
84DYRK1A0.65250258
85IRAK40.64710592
86PLK20.63869907
87VRK10.62686334
88SGK20.62162413
89MAP3K130.61809743
90EIF2AK20.61269206
91SGK10.61175111
92PHKG10.60419311
93PHKG20.60419311
94CDK80.60292813
95BMPR1B0.59439044
96MAPK70.59290615
97FGFR30.59236134
98TEC0.58667716
99PRKG10.57390802
100ERBB20.57178698
101RPS6KB20.56688268
102MAPK150.56291130
103CSNK1G30.55176736
104NEK10.54282712
105ITK0.54108728
106CSNK1G20.52850321
107TAF10.52696063
108CDK70.51614347
109PRKCH0.51346943
110TAOK30.51213178
111STK380.51010268
112FGFR10.50978533
113CHEK10.50069155
114CSNK1D0.49956149
115CAMK40.49613649
116PAK30.47978278
117ADRBK10.47770207
118BCR0.47139550
119ROCK20.46988482
120CDK10.46378357
121LCK0.46339607
122SGK2230.45698850
123SGK4940.45698850
124PRKD30.45098906
125ATM0.44546081
126CDK50.44468813
127MAP3K70.43937950
128KSR10.43537454
129ATR0.43375135
130ZAK0.43135908
131MAPK100.42907144
132MAP3K60.42288818
133TTK0.42267714
134DYRK20.41823642
135PRKCE0.41440375
136PRKCQ0.41257103
137IRAK10.40422984
138PRKAA20.40149109
139CDK20.39127018
140AKT30.38732102
141CDK40.38692141
142EPHA30.38526553
143MAPKAPK50.38140686
144GSK3B0.37685540
145FYN0.37660084
146MAPK140.36278521
147RPS6KA40.34409499

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.83101049
2Nicotine addiction_Homo sapiens_hsa050332.61812393
3Nucleotide excision repair_Homo sapiens_hsa034201.87605356
4Glutamatergic synapse_Homo sapiens_hsa047241.86904396
5Fanconi anemia pathway_Homo sapiens_hsa034601.85987670
6Morphine addiction_Homo sapiens_hsa050321.85470056
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.74801943
8Lysine degradation_Homo sapiens_hsa003101.69348295
9RNA transport_Homo sapiens_hsa030131.60184995
10Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.58154209
11Olfactory transduction_Homo sapiens_hsa047401.56338558
12Circadian entrainment_Homo sapiens_hsa047131.50416321
13Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47732904
14p53 signaling pathway_Homo sapiens_hsa041151.44650649
15Axon guidance_Homo sapiens_hsa043601.44051868
16Serotonergic synapse_Homo sapiens_hsa047261.44040536
17Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.42935140
18Taste transduction_Homo sapiens_hsa047421.41561328
19Long-term depression_Homo sapiens_hsa047301.40690940
20Steroid biosynthesis_Homo sapiens_hsa001001.37666492
21Non-homologous end-joining_Homo sapiens_hsa034501.35358432
22GABAergic synapse_Homo sapiens_hsa047271.34552727
23Homologous recombination_Homo sapiens_hsa034401.31870220
24One carbon pool by folate_Homo sapiens_hsa006701.30563574
25Primary immunodeficiency_Homo sapiens_hsa053401.29303584
26Protein export_Homo sapiens_hsa030601.29029078
27Nitrogen metabolism_Homo sapiens_hsa009101.28799588
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26955825
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25570892
30Wnt signaling pathway_Homo sapiens_hsa043101.22790915
31Calcium signaling pathway_Homo sapiens_hsa040201.22604263
32Long-term potentiation_Homo sapiens_hsa047201.22017068
33Adherens junction_Homo sapiens_hsa045201.21658838
34Salivary secretion_Homo sapiens_hsa049701.21573667
35Amphetamine addiction_Homo sapiens_hsa050311.19831695
36Basal cell carcinoma_Homo sapiens_hsa052171.18850287
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.18247426
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.18225503
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.15586481
40Endometrial cancer_Homo sapiens_hsa052131.14512187
41Autoimmune thyroid disease_Homo sapiens_hsa053201.13412998
42Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.12021790
43Cholinergic synapse_Homo sapiens_hsa047251.11783406
44Selenocompound metabolism_Homo sapiens_hsa004501.11388667
45Dopaminergic synapse_Homo sapiens_hsa047281.10196205
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08541848
47Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07839505
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.04512606
49Regulation of autophagy_Homo sapiens_hsa041401.04466000
50Oxytocin signaling pathway_Homo sapiens_hsa049211.04430310
51Renin secretion_Homo sapiens_hsa049241.03384971
52cAMP signaling pathway_Homo sapiens_hsa040241.02700613
53Graft-versus-host disease_Homo sapiens_hsa053321.02686583
54Melanogenesis_Homo sapiens_hsa049161.00846943
55Hippo signaling pathway_Homo sapiens_hsa043901.00760050
56T cell receptor signaling pathway_Homo sapiens_hsa046600.99532162
57FoxO signaling pathway_Homo sapiens_hsa040680.97606580
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96593807
59Basal transcription factors_Homo sapiens_hsa030220.96233792
60Butanoate metabolism_Homo sapiens_hsa006500.94804243
61Cocaine addiction_Homo sapiens_hsa050300.92823929
62Allograft rejection_Homo sapiens_hsa053300.92162477
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91738276
64Hedgehog signaling pathway_Homo sapiens_hsa043400.91153861
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.90584698
66Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.89650291
67Insulin secretion_Homo sapiens_hsa049110.88583151
68Ether lipid metabolism_Homo sapiens_hsa005650.88438889
69Thyroid cancer_Homo sapiens_hsa052160.87827496
70Longevity regulating pathway - mammal_Homo sapiens_hsa042110.87288648
71Hematopoietic cell lineage_Homo sapiens_hsa046400.87076699
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86857141
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85313657
74Non-small cell lung cancer_Homo sapiens_hsa052230.83971458
75Oocyte meiosis_Homo sapiens_hsa041140.83675423
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83520660
77Gastric acid secretion_Homo sapiens_hsa049710.83150406
78GnRH signaling pathway_Homo sapiens_hsa049120.81331704
79Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81294814
80MAPK signaling pathway_Homo sapiens_hsa040100.80636111
81Ovarian steroidogenesis_Homo sapiens_hsa049130.80477034
82Propanoate metabolism_Homo sapiens_hsa006400.78097860
83Ras signaling pathway_Homo sapiens_hsa040140.77206144
84Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.75988298
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.75279440
86Choline metabolism in cancer_Homo sapiens_hsa052310.75085918
87TGF-beta signaling pathway_Homo sapiens_hsa043500.74996600
88Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.74946757
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74753161
90ABC transporters_Homo sapiens_hsa020100.74465841
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.73787093
92Mismatch repair_Homo sapiens_hsa034300.73021934
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72166287
94Alcoholism_Homo sapiens_hsa050340.71798536
95Dilated cardiomyopathy_Homo sapiens_hsa054140.71442496
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71088275
97Notch signaling pathway_Homo sapiens_hsa043300.71054104
98mTOR signaling pathway_Homo sapiens_hsa041500.70972311
99Spliceosome_Homo sapiens_hsa030400.70255294
100ErbB signaling pathway_Homo sapiens_hsa040120.69998801
101Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69418814
102Circadian rhythm_Homo sapiens_hsa047100.68586690
103Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68296858
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68208017
105DNA replication_Homo sapiens_hsa030300.67932661
106MicroRNAs in cancer_Homo sapiens_hsa052060.67635004
107Asthma_Homo sapiens_hsa053100.66631129
108Dorso-ventral axis formation_Homo sapiens_hsa043200.66280788
109Rap1 signaling pathway_Homo sapiens_hsa040150.64774577
110Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.64650304
111Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64344770
112Linoleic acid metabolism_Homo sapiens_hsa005910.64169348
113Fatty acid biosynthesis_Homo sapiens_hsa000610.63580369
114Intestinal immune network for IgA production_Homo sapiens_hsa046720.62671833
115Gap junction_Homo sapiens_hsa045400.62353285
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.61915742
117mRNA surveillance pathway_Homo sapiens_hsa030150.61688137
118B cell receptor signaling pathway_Homo sapiens_hsa046620.61228047
119Prostate cancer_Homo sapiens_hsa052150.59581961
120RNA polymerase_Homo sapiens_hsa030200.58471837
121Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.58386950
122Chemokine signaling pathway_Homo sapiens_hsa040620.58164685
123Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57851704
124Pathways in cancer_Homo sapiens_hsa052000.57604703
125RNA degradation_Homo sapiens_hsa030180.56548037
126Cell cycle_Homo sapiens_hsa041100.56049780
127Small cell lung cancer_Homo sapiens_hsa052220.56008954
128Melanoma_Homo sapiens_hsa052180.55839424
129Sphingolipid metabolism_Homo sapiens_hsa006000.55493193
130Prolactin signaling pathway_Homo sapiens_hsa049170.54275880
131Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.52349236
132Type I diabetes mellitus_Homo sapiens_hsa049400.51487739
133Pancreatic secretion_Homo sapiens_hsa049720.51268505
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.51047006
135Hepatitis B_Homo sapiens_hsa051610.49218257
136Inositol phosphate metabolism_Homo sapiens_hsa005620.49164012
137Base excision repair_Homo sapiens_hsa034100.48881119
138Colorectal cancer_Homo sapiens_hsa052100.48830447
139Measles_Homo sapiens_hsa051620.48281821
140Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48261956
141Chronic myeloid leukemia_Homo sapiens_hsa052200.48109177
142Systemic lupus erythematosus_Homo sapiens_hsa053220.46882695
143HTLV-I infection_Homo sapiens_hsa051660.46811834
144Purine metabolism_Homo sapiens_hsa002300.44577198
145NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43605328
146alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.41163448
147Glioma_Homo sapiens_hsa052140.40490687
148Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40470371
149Viral carcinogenesis_Homo sapiens_hsa052030.39459416

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