ENHO

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)6.72713361
2cerebellar granule cell differentiation (GO:0021707)4.90383133
3central nervous system myelination (GO:0022010)4.87412041
4axon ensheathment in central nervous system (GO:0032291)4.87412041
5L-amino acid import (GO:0043092)4.83030057
6positive regulation of synapse maturation (GO:0090129)4.70475818
7positive regulation of dendritic spine development (GO:0060999)4.46197040
8amino acid import (GO:0043090)4.29804422
9regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.16659710
10positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.07909563
11presynaptic membrane organization (GO:0097090)4.07827790
12negative regulation of synaptic transmission, GABAergic (GO:0032229)3.95968032
13synaptic vesicle endocytosis (GO:0048488)3.93663185
14positive regulation of membrane potential (GO:0045838)3.84708098
15regulation of short-term neuronal synaptic plasticity (GO:0048172)3.83974435
16regulation of excitatory postsynaptic membrane potential (GO:0060079)3.79938871
17regulation of synapse maturation (GO:0090128)3.78708806
18neuromuscular process controlling balance (GO:0050885)3.71882329
19regulation of voltage-gated calcium channel activity (GO:1901385)3.69451680
20synaptic vesicle exocytosis (GO:0016079)3.69393217
21dendritic spine organization (GO:0097061)3.65314325
22locomotory exploration behavior (GO:0035641)3.64731856
23regulation of neurotransmitter secretion (GO:0046928)3.63469154
24positive regulation of dendritic spine morphogenesis (GO:0061003)3.59476200
25gamma-aminobutyric acid transport (GO:0015812)3.56482471
26neuronal action potential propagation (GO:0019227)3.56019611
27neuron-neuron synaptic transmission (GO:0007270)3.55867275
28regulation of postsynaptic membrane potential (GO:0060078)3.54465475
29mechanosensory behavior (GO:0007638)3.54138731
30synaptic vesicle maturation (GO:0016188)3.53273416
31neurotransmitter uptake (GO:0001504)3.52578204
32regulation of dendritic spine morphogenesis (GO:0061001)3.51880525
33cerebellar Purkinje cell differentiation (GO:0021702)3.51465986
34regulation of synaptic plasticity (GO:0048167)3.51439154
35acidic amino acid transport (GO:0015800)3.48646621
36regulation of dendritic spine development (GO:0060998)3.46756769
37cell migration in hindbrain (GO:0021535)3.42316915
38regulation of neurotransmitter transport (GO:0051588)3.41206938
39alanine transport (GO:0032328)3.35092660
40neuron cell-cell adhesion (GO:0007158)3.34580675
41vocalization behavior (GO:0071625)3.30072102
42endocrine pancreas development (GO:0031018)3.28949201
43neurotransmitter secretion (GO:0007269)3.26294834
44positive regulation of neurotransmitter transport (GO:0051590)3.24587215
45establishment of mitochondrion localization (GO:0051654)3.24466275
46regulation of ARF protein signal transduction (GO:0032012)3.24114360
47cell communication by electrical coupling (GO:0010644)3.21875301
48negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.19007954
49regulation of synaptic vesicle exocytosis (GO:2000300)3.17418326
50membrane depolarization (GO:0051899)3.15169144
51cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.10547424
52L-glutamate transport (GO:0015813)3.10464555
53cell differentiation in hindbrain (GO:0021533)3.09057132
54long-term memory (GO:0007616)3.08537883
55positive regulation of dendrite development (GO:1900006)3.08485411
56membrane depolarization during action potential (GO:0086010)3.05180855
57regulation of synaptic transmission (GO:0050804)3.04203416
58gamma-aminobutyric acid signaling pathway (GO:0007214)3.02869185
59glutamate secretion (GO:0014047)3.00676460
60COPI coating of Golgi vesicle (GO:0048205)3.00554914
61Golgi transport vesicle coating (GO:0048200)3.00554914
62cellular potassium ion homeostasis (GO:0030007)2.99485834
63synaptic vesicle transport (GO:0048489)2.98865811
64establishment of synaptic vesicle localization (GO:0097480)2.98865811
65positive regulation of neurotransmitter secretion (GO:0001956)2.97631541
66regulation of female receptivity (GO:0045924)2.96778230
67membrane hyperpolarization (GO:0060081)2.96133892
68cerebellar Purkinje cell layer development (GO:0021680)2.95770083
69adult walking behavior (GO:0007628)2.95307084
70synaptic transmission (GO:0007268)2.93492691
71detection of calcium ion (GO:0005513)2.89285256
72protein maturation by protein folding (GO:0022417)2.86797205
73membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.84450572
74insulin secretion (GO:0030073)2.83457011
75negative regulation of catecholamine secretion (GO:0033604)2.81507798
76proline transport (GO:0015824)2.80944285
77exploration behavior (GO:0035640)2.80763289
78layer formation in cerebral cortex (GO:0021819)2.80669424
79regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.78905299
80dendritic spine morphogenesis (GO:0060997)2.78013949
81peptide hormone processing (GO:0016486)2.77198461
82regulation of synaptic vesicle transport (GO:1902803)2.74315815
83regulation of beta-amyloid formation (GO:1902003)2.72320203
84nitric oxide mediated signal transduction (GO:0007263)2.71332050
85neurotransmitter transport (GO:0006836)2.70453595
86regulation of neuronal synaptic plasticity (GO:0048168)2.67566144
87regulation of calcium ion-dependent exocytosis (GO:0017158)2.66885343
88regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.66626785
89postsynaptic membrane organization (GO:0001941)2.66459014
90positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.65914234
91positive regulation of insulin secretion (GO:0032024)2.65876372
92auditory behavior (GO:0031223)2.64917887
93sodium ion export (GO:0071436)2.63951530
94neurotransmitter-gated ion channel clustering (GO:0072578)2.63187712
95activation of protein kinase A activity (GO:0034199)2.63155130
96regulation of glutamate receptor signaling pathway (GO:1900449)2.62581007
97regulation of amyloid precursor protein catabolic process (GO:1902991)2.61398335
98regulation of vesicle fusion (GO:0031338)2.59673229
99neuron recognition (GO:0008038)2.58428055
100regulation of insulin secretion (GO:0050796)2.57091663
101response to auditory stimulus (GO:0010996)2.56908961
102regulation of neurotransmitter levels (GO:0001505)2.56621639
103regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.56268715
104transmission of nerve impulse (GO:0019226)2.54342742
105cellular response to glucagon stimulus (GO:0071377)2.53959354
106neuromuscular process controlling posture (GO:0050884)2.53229773
107regulation of synapse structural plasticity (GO:0051823)2.52277664
108protein localization to synapse (GO:0035418)2.50392595
109potassium ion import (GO:0010107)2.49484540
110cochlea development (GO:0090102)2.46286878
111C4-dicarboxylate transport (GO:0015740)2.45241752
112regulation of long-term neuronal synaptic plasticity (GO:0048169)2.45177022
113presynaptic membrane assembly (GO:0097105)2.44982870
114ionotropic glutamate receptor signaling pathway (GO:0035235)2.44312323
115potassium ion homeostasis (GO:0055075)2.44272577
116dendrite morphogenesis (GO:0048813)2.43894143
117innervation (GO:0060384)2.43381066
118synaptic transmission, glutamatergic (GO:0035249)2.42899879
119cellular sodium ion homeostasis (GO:0006883)2.40946683
120response to dietary excess (GO:0002021)2.39485744
121positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.39387470
122positive regulation of synaptic transmission, GABAergic (GO:0032230)2.37828834
123regulation of peptide hormone secretion (GO:0090276)2.35798927
124regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178)2.34996915
125regulation of peptide secretion (GO:0002791)2.34317234
126glutamate receptor signaling pathway (GO:0007215)2.34128004
127positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.33225470
128regulation of respiratory system process (GO:0044065)2.33070930
129positive regulation of peptide secretion (GO:0002793)2.32777634
130signal release (GO:0023061)2.31738357
131positive regulation of peptide hormone secretion (GO:0090277)2.31565108
132L-phenylalanine catabolic process (GO:0006559)2.31481441
133erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.31481441
134positive regulation of exocytosis (GO:0045921)2.30051705
135neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.29327098
136axonal fasciculation (GO:0007413)2.29249341
137neuronal ion channel clustering (GO:0045161)2.28230525
138negative regulation of norepinephrine secretion (GO:0010700)2.27414056
139regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.25583687
140cellular response to leptin stimulus (GO:0044320)2.25305430
141calcium-mediated signaling using intracellular calcium source (GO:0035584)2.25007602
142regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.24810332
143cellular zinc ion homeostasis (GO:0006882)2.24245782
144negative regulation of astrocyte differentiation (GO:0048712)2.23871585
145pyrimidine nucleobase catabolic process (GO:0006208)2.23585502
146response to leptin (GO:0044321)2.23351544
147synapse assembly (GO:0007416)2.23153314
148retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.22497720
149cholesterol catabolic process (GO:0006707)2.21990584

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.99580105
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.99844368
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.94789674
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.78399045
5JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74634127
6SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.60708307
7* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58300571
8SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.56791374
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.54420779
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.54379137
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.54379137
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.52305113
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.51347109
14GBX2_23144817_ChIP-Seq_PC3_Human2.46406649
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.42624940
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.42185706
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.41189013
18RCOR2_21632747_ChIP-Seq_MESCs_Mouse2.37223611
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.33004513
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.13637285
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.08612177
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.06912186
23DROSHA_22980978_ChIP-Seq_HELA_Human2.01956701
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.92822136
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.84715282
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83119774
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.82153938
28ERG_21242973_ChIP-ChIP_JURKAT_Human1.81544380
29RARB_27405468_Chip-Seq_BRAIN_Mouse1.80248424
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.62570679
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57833612
32ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.50709104
33NR3C1_23031785_ChIP-Seq_PC12_Mouse1.47526270
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.47095554
35ZNF274_21170338_ChIP-Seq_K562_Hela1.44489794
36PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42335278
37IKZF1_21737484_ChIP-ChIP_HCT116_Human1.40415300
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.40051380
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.37284264
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.34901972
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31450924
42RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30812848
43BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30115884
44ZFP281_27345836_Chip-Seq_ESCs_Mouse1.28386459
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28284297
46SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28020814
47AR_21572438_ChIP-Seq_LNCaP_Human1.25438990
48OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.24671140
49* FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.23231974
50PIAS1_25552417_ChIP-Seq_VCAP_Human1.22273601
51GATA1_26923725_Chip-Seq_HPCs_Mouse1.20610334
52SMAD4_21799915_ChIP-Seq_A2780_Human1.19382419
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.19001893
54CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18427224
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18312416
56DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16575503
57SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.15956050
58SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.15927600
59* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.11816699
60SOX2_21211035_ChIP-Seq_LN229_Gbm1.10220612
61ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.09682430
62RING1B_27294783_Chip-Seq_NPCs_Mouse1.08740936
63RXR_22158963_ChIP-Seq_LIVER_Mouse1.06834412
64TP53_20018659_ChIP-ChIP_R1E_Mouse1.05279072
65TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05075955
66TAF15_26573619_Chip-Seq_HEK293_Human1.03457496
67P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03420805
68WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02446901
69ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02101590
70P300_19829295_ChIP-Seq_ESCs_Human1.01474998
71BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01144142
72SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00089852
73BCAT_22108803_ChIP-Seq_LS180_Human0.99987349
74OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99721166
75TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98977830
76LXR_22158963_ChIP-Seq_LIVER_Mouse0.98436558
77SMAD3_21741376_ChIP-Seq_EPCs_Human0.98197284
78AR_19668381_ChIP-Seq_PC3_Human0.98090158
79* CTCF_27219007_Chip-Seq_Bcells_Human0.97813961
80IGF1R_20145208_ChIP-Seq_DFB_Human0.97165209
81* OCT4_19829295_ChIP-Seq_ESCs_Human0.97117368
82ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95862480
83* AR_25329375_ChIP-Seq_VCAP_Human0.93339313
84SMC4_20622854_ChIP-Seq_HELA_Human0.92367833
85LXR_22292898_ChIP-Seq_THP-1_Human0.91913385
86NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91844515
87ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.91721008
88KDM2B_26808549_Chip-Seq_K562_Human0.91621384
89SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.91482309
90ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90662315
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90544659
92EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90392245
93STAT3_23295773_ChIP-Seq_U87_Human0.90051625
94CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.88341865
95EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.87693872
96TET1_21490601_ChIP-Seq_MESCs_Mouse0.86898781
97TRIM28_21343339_ChIP-Seq_HEK293_Human0.86824656
98* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.86415381
99* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.86261032
100YAP1_20516196_ChIP-Seq_MESCs_Mouse0.85901862
101SMAD3_21741376_ChIP-Seq_ESCs_Human0.85358728
102HTT_18923047_ChIP-ChIP_STHdh_Human0.85325340
103SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.84982625
104* KLF4_19829295_ChIP-Seq_ESCs_Human0.84941691
105TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84416322
106GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84188513
107ZFP281_18757296_ChIP-ChIP_E14_Mouse0.83819180
108LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82318853
109SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.81333222
110DPY_21335234_ChIP-Seq_ESCs_Mouse0.80946520
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.80683745
112RUNX2_22187159_ChIP-Seq_PCA_Human0.80194165
113SMAD4_21741376_ChIP-Seq_ESCs_Human0.79373407
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.78640311
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78346728
116RUNX1_26923725_Chip-Seq_HPCs_Mouse0.78296737
117SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.78292889
118WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.77843054
119CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.77683407
120ARNT_22903824_ChIP-Seq_MCF-7_Human0.77413487
121SMAD4_21741376_ChIP-Seq_HESCs_Human0.77310229
122ESR2_21235772_ChIP-Seq_MCF-7_Human0.77177738
123RNF2_27304074_Chip-Seq_NSC_Mouse0.77026742
124CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.74499514
125NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.73597685
126MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.73309327
127SOX9_26525672_Chip-Seq_HEART_Mouse0.73176617
128P68_20966046_ChIP-Seq_HELA_Human0.72277976
129TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.71697716

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.27642773
2MP0009780_abnormal_chondrocyte_physiolo3.21887380
3MP0004270_analgesia3.01906852
4MP0002909_abnormal_adrenal_gland2.94216176
5MP0003635_abnormal_synaptic_transmissio2.74689609
6MP0003283_abnormal_digestive_organ2.67623978
7MP0002837_dystrophic_cardiac_calcinosis2.34691685
8MP0003880_abnormal_central_pattern2.30660217
9MP0002139_abnormal_hepatobiliary_system2.19546132
10MP0003329_amyloid_beta_deposits2.19066883
11MP0005423_abnormal_somatic_nervous2.17491023
12MP0004043_abnormal_pH_regulation2.12185573
13MP0002063_abnormal_learning/memory/cond2.09886289
14MP0009745_abnormal_behavioral_response2.09089158
15MP0002064_seizures2.07765874
16MP0002734_abnormal_mechanical_nocicepti2.07056098
17MP0005646_abnormal_pituitary_gland2.02619499
18MP0001486_abnormal_startle_reflex2.00840067
19MP0002572_abnormal_emotion/affect_behav1.97885699
20MP0002733_abnormal_thermal_nociception1.93695162
21MP0004858_abnormal_nervous_system1.86537014
22MP0002272_abnormal_nervous_system1.83311843
23MP0004742_abnormal_vestibular_system1.81229996
24MP0006276_abnormal_autonomic_nervous1.80737698
25MP0000013_abnormal_adipose_tissue1.79975807
26MP0001968_abnormal_touch/_nociception1.77246861
27MP0003787_abnormal_imprinting1.77077810
28MP0010386_abnormal_urinary_bladder1.73788786
29MP0004885_abnormal_endolymph1.72391224
30MP0002693_abnormal_pancreas_physiology1.71506903
31MP0003195_calcinosis1.69877699
32MP0005645_abnormal_hypothalamus_physiol1.68550906
33MP0001944_abnormal_pancreas_morphology1.68547361
34MP0002638_abnormal_pupillary_reflex1.67753300
35MP0009046_muscle_twitch1.66786616
36MP0005379_endocrine/exocrine_gland_phen1.59231200
37MP0001970_abnormal_pain_threshold1.59212819
38MP0002557_abnormal_social/conspecific_i1.54404630
39MP0001502_abnormal_circadian_rhythm1.51975856
40MP0001501_abnormal_sleep_pattern1.50885892
41MP0001984_abnormal_olfaction1.50503041
42MP0000920_abnormal_myelination1.45105293
43MP0002735_abnormal_chemical_nociception1.44796041
44MP0001440_abnormal_grooming_behavior1.43696855
45MP0000955_abnormal_spinal_cord1.42321147
46MP0006072_abnormal_retinal_apoptosis1.40873507
47MP0002067_abnormal_sensory_capabilities1.40581847
48MP0003122_maternal_imprinting1.39819786
49MP0002822_catalepsy1.37508274
50MP0002736_abnormal_nociception_after1.37235198
51MP0005167_abnormal_blood-brain_barrier1.37112110
52MP0008569_lethality_at_weaning1.36834529
53MP0005365_abnormal_bile_salt1.35493862
54MP0002184_abnormal_innervation1.34847394
55MP0000678_abnormal_parathyroid_gland1.30709829
56MP0002078_abnormal_glucose_homeostasis1.29539223
57MP0003690_abnormal_glial_cell1.27953414
58MP0001177_atelectasis1.27912651
59MP0003136_yellow_coat_color1.26517293
60MP0000778_abnormal_nervous_system1.25319150
61MP0002877_abnormal_melanocyte_morpholog1.25122650
62MP0003634_abnormal_glial_cell1.25073053
63MP0003879_abnormal_hair_cell1.20695954
64MP0001986_abnormal_taste_sensitivity1.20534398
65MP0005535_abnormal_body_temperature1.19956689
66MP0000631_abnormal_neuroendocrine_gland1.18549926
67MP0003123_paternal_imprinting1.18052013
68MP0000462_abnormal_digestive_system1.17368757
69MP0005386_behavior/neurological_phenoty1.16230404
70MP0004924_abnormal_behavior1.16230404
71MP0000566_synostosis1.16077071
72MP0005083_abnormal_biliary_tract1.16066751
73MP0002882_abnormal_neuron_morphology1.11113772
74MP0002066_abnormal_motor_capabilities/c1.09228047
75MP0003633_abnormal_nervous_system1.09207881
76MP0005085_abnormal_gallbladder_physiolo1.06264087
77MP0000604_amyloidosis1.06147496
78MP0001905_abnormal_dopamine_level1.04019178
79MP0004142_abnormal_muscle_tone1.02685726
80MP0001188_hyperpigmentation1.01091721
81MP0004811_abnormal_neuron_physiology1.00772328
82MP0001529_abnormal_vocalization1.00344179
83MP0002653_abnormal_ependyma_morphology0.99023725
84MP0003632_abnormal_nervous_system0.98949125
85MP0003183_abnormal_peptide_metabolism0.98109079
86MP0004145_abnormal_muscle_electrophysio0.95602409
87MP0001299_abnormal_eye_distance/0.95317176
88MP0003868_abnormal_feces_composition0.94597760
89MP0001485_abnormal_pinna_reflex0.94190745
90MP0003953_abnormal_hormone_level0.92755814
91MP0003121_genomic_imprinting0.92709084
92MP0005360_urolithiasis0.91538955
93MP0002069_abnormal_eating/drinking_beha0.91308161
94MP0002752_abnormal_somatic_nervous0.87289243
95MP0003631_nervous_system_phenotype0.86958186
96MP0002229_neurodegeneration0.86087688
97MP0008961_abnormal_basal_metabolism0.86052136
98MP0005551_abnormal_eye_electrophysiolog0.85385627
99MP0003075_altered_response_to0.83707631
100MP0002234_abnormal_pharynx_morphology0.83119179
101MP0004085_abnormal_heartbeat0.81996402
102MP0002152_abnormal_brain_morphology0.80900575
103MP0000751_myopathy0.80466277
104MP0005253_abnormal_eye_physiology0.80262970
105MP0005220_abnormal_exocrine_pancreas0.80181865
106MP0001346_abnormal_lacrimal_gland0.79617617
107MP0001963_abnormal_hearing_physiology0.79299728
108MP0002876_abnormal_thyroid_physiology0.78150339
109MP0008877_abnormal_DNA_methylation0.77643352
110MP0003137_abnormal_impulse_conducting0.77477374
111MP0010329_abnormal_lipoprotein_level0.77020161
112MP0009840_abnormal_foam_cell0.76886016
113MP0002249_abnormal_larynx_morphology0.74471036
114MP0005332_abnormal_amino_acid0.74137723
115MP0008875_abnormal_xenobiotic_pharmacok0.74135308
116MP0008872_abnormal_physiological_respon0.73856460
117MP0002118_abnormal_lipid_homeostasis0.72641267
118MP0000026_abnormal_inner_ear0.72247926
119MP0003861_abnormal_nervous_system0.72216180
120MP0006292_abnormal_olfactory_placode0.70245904
121MP0000579_abnormal_nail_morphology0.69966383
122MP0003938_abnormal_ear_development0.69154322
123MP0005623_abnormal_meninges_morphology0.66189896
124MP0005499_abnormal_olfactory_system0.64833915
125MP0005394_taste/olfaction_phenotype0.64833915
126MP0008874_decreased_physiological_sensi0.62091804
127MP0004133_heterotaxia0.61141248
128MP0009379_abnormal_foot_pigmentation0.59838858
129MP0005377_hearing/vestibular/ear_phenot0.55830761
130MP0003878_abnormal_ear_physiology0.55830761
131MP0010769_abnormal_survival0.55482521
132MP0004130_abnormal_muscle_cell0.54450730
133MP0005409_darkened_coat_color0.53644289
134MP0010770_preweaning_lethality0.52753840
135MP0002082_postnatal_lethality0.52753840

Predicted human phenotypes

RankGene SetZ-score
1Hyperinsulinemic hypoglycemia (HP:0000825)4.89305330
2Febrile seizures (HP:0002373)4.68156817
3Hypoglycemic seizures (HP:0002173)4.63435169
4Symptomatic seizures (HP:0011145)3.96403593
5Myokymia (HP:0002411)3.93770061
6Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.81794931
7Hypoglycemic coma (HP:0001325)3.81723402
8Focal motor seizures (HP:0011153)3.79325750
9Visual hallucinations (HP:0002367)3.75477409
10Megalencephaly (HP:0001355)3.56227425
11Ketoacidosis (HP:0001993)3.53978969
12Annular pancreas (HP:0001734)3.49393419
13Spastic gait (HP:0002064)3.48688093
14Neurofibrillary tangles (HP:0002185)3.32506328
15Urinary bladder sphincter dysfunction (HP:0002839)3.29181036
16Pheochromocytoma (HP:0002666)3.23865843
17Abnormality of calcium-phosphate metabolism (HP:0100530)3.15935135
18Agitation (HP:0000713)3.10798600
19Late onset (HP:0003584)3.03945429
20Mutism (HP:0002300)3.02557976
21Intention tremor (HP:0002080)2.99322765
22Delusions (HP:0000746)2.90729940
23Abnormality of aromatic amino acid family metabolism (HP:0004338)2.90320265
24Supranuclear gaze palsy (HP:0000605)2.89079419
25Cerebral inclusion bodies (HP:0100314)2.86392938
26Dysmetria (HP:0001310)2.85774785
27Cerebral hypomyelination (HP:0006808)2.83477936
28Large for gestational age (HP:0001520)2.83346799
29Impaired vibration sensation in the lower limbs (HP:0002166)2.81722975
30Postural instability (HP:0002172)2.81519612
31Focal seizures (HP:0007359)2.81016121
32EEG with generalized epileptiform discharges (HP:0011198)2.78860727
33Hypsarrhythmia (HP:0002521)2.77536386
34Sleep apnea (HP:0010535)2.75666725
35Poor eye contact (HP:0000817)2.75421677
36Urinary urgency (HP:0000012)2.70927092
37Epileptiform EEG discharges (HP:0011182)2.70585104
38Neuroendocrine neoplasm (HP:0100634)2.69854311
39Anxiety (HP:0000739)2.68927260
40Peripheral hypomyelination (HP:0007182)2.68336868
41Focal dystonia (HP:0004373)2.66816362
42Obstructive sleep apnea (HP:0002870)2.64125805
43Hemiparesis (HP:0001269)2.63857301
44Akinesia (HP:0002304)2.63717980
45Atonic seizures (HP:0010819)2.60460781
46Generalized tonic-clonic seizures (HP:0002069)2.60006576
47Ketosis (HP:0001946)2.58415111
48Abnormality of the corticospinal tract (HP:0002492)2.54391601
49Epileptic encephalopathy (HP:0200134)2.53871925
50Hyperglycemia (HP:0003074)2.53797007
51Action tremor (HP:0002345)2.50563353
52Tetraplegia (HP:0002445)2.49621500
53Aplasia involving bones of the upper limbs (HP:0009823)2.48093441
54Aplasia of the phalanges of the hand (HP:0009802)2.48093441
55Aplasia involving bones of the extremities (HP:0009825)2.48093441
56Depression (HP:0000716)2.44933942
57Abnormality of endocrine pancreas physiology (HP:0012093)2.44650572
58Abnormality of the pancreatic islet cells (HP:0006476)2.44650572
59Abnormal social behavior (HP:0012433)2.44279100
60Impaired social interactions (HP:0000735)2.44279100
61Craniofacial dystonia (HP:0012179)2.40457768
62Limb dystonia (HP:0002451)2.39454263
63Progressive cerebellar ataxia (HP:0002073)2.39311947
64Bradykinesia (HP:0002067)2.29726793
65Clonus (HP:0002169)2.29706764
66Abnormality of binocular vision (HP:0011514)2.26074469
67Diplopia (HP:0000651)2.26074469
68Absence seizures (HP:0002121)2.25261232
69Insulin-resistant diabetes mellitus (HP:0000831)2.22804786
70Hemiplegia (HP:0002301)2.21222121
71Anomalous pulmonary venous return (HP:0010772)2.21137950
72Morphological abnormality of the pyramidal tract (HP:0002062)2.20986912
73Abnormality of the lower motor neuron (HP:0002366)2.19203216
74Postural tremor (HP:0002174)2.18847214
75Degeneration of the lateral corticospinal tracts (HP:0002314)2.17904443
76Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.17904443
77Stereotypic behavior (HP:0000733)2.17694258
78Lower limb muscle weakness (HP:0007340)2.17326205
79Abnormal pancreas size (HP:0012094)2.15382081
80Spastic tetraparesis (HP:0001285)2.14427241
81Retinal atrophy (HP:0001105)2.14213603
82Neuronal loss in central nervous system (HP:0002529)2.12520338
83Synostosis involving the elbow (HP:0003938)2.12305168
84Humeroradial synostosis (HP:0003041)2.12305168
85Apathy (HP:0000741)2.08972292
86Restlessness (HP:0000711)2.08567208
87Broad-based gait (HP:0002136)2.08246118
88Insomnia (HP:0100785)2.08021678
89Hyperparathyroidism (HP:0000843)2.07533407
90Ventricular fibrillation (HP:0001663)2.06873015
91Dialeptic seizures (HP:0011146)2.05372888
92Truncal ataxia (HP:0002078)2.04190543
93Acute necrotizing encephalopathy (HP:0006965)2.03247523
94Hyperventilation (HP:0002883)2.02236650
95Pancreatic islet-cell hyperplasia (HP:0004510)2.01359528
96Decreased circulating renin level (HP:0003351)2.01352705
97Failure to thrive in infancy (HP:0001531)2.00584653
98Gout (HP:0001997)1.99586891
99Papilledema (HP:0001085)1.97935190
100Split foot (HP:0001839)1.93735032
101Abnormal eating behavior (HP:0100738)1.93229306
102Acute encephalopathy (HP:0006846)1.92733129
103Xanthomatosis (HP:0000991)1.92135810
104Rigidity (HP:0002063)1.90946061
105Conjugated hyperbilirubinemia (HP:0002908)1.90184053
106Status epilepticus (HP:0002133)1.89968030
107Urinary glycosaminoglycan excretion (HP:0003541)1.89590301
108Mucopolysacchariduria (HP:0008155)1.89590301
109Bronchomalacia (HP:0002780)1.89126151
110Choreoathetosis (HP:0001266)1.89065302
111Hypercortisolism (HP:0001578)1.88966974
112Abnormality of the pulmonary veins (HP:0011718)1.87564525
113Diminished motivation (HP:0000745)1.87453264
114Progressive macrocephaly (HP:0004481)1.86953715
115Abnormal mitochondria in muscle tissue (HP:0008316)1.86781820
116Ankle clonus (HP:0011448)1.86394854
117Impaired smooth pursuit (HP:0007772)1.85905502
118Absent speech (HP:0001344)1.82468240
119Truncus arteriosus (HP:0001660)1.82402523
120Impaired vibratory sensation (HP:0002495)1.81664394
121Increased circulating renin level (HP:0000848)1.81537789
122Incomplete penetrance (HP:0003829)1.81291896
123Prolonged partial thromboplastin time (HP:0003645)1.79462265
124Abnormality of the labia minora (HP:0012880)1.79178879
125Lower limb asymmetry (HP:0100559)1.78367094
126Esotropia (HP:0000565)1.77773312
127Intrahepatic cholestasis (HP:0001406)1.77602520
128CNS hypomyelination (HP:0003429)1.76579098
129Hyperlipoproteinemia (HP:0010980)1.76214879
130Unilateral renal agenesis (HP:0000122)1.75042313
131Spastic tetraplegia (HP:0002510)1.73831872
132Abnormality of polysaccharide metabolism (HP:0011012)1.73625944
133Abnormality of glycosaminoglycan metabolism (HP:0004371)1.73625944
134Abnormality of mucopolysaccharide metabolism (HP:0011020)1.73625944
135Hypokalemia (HP:0002900)1.73197877
136Back pain (HP:0003418)1.71202669
137Torticollis (HP:0000473)1.70889927
138Prolonged QT interval (HP:0001657)1.70477584
139Polyphagia (HP:0002591)1.70443758
140Retinal dysplasia (HP:0007973)1.70336163
141Morphological abnormality of the inner ear (HP:0011390)1.69970734
142Double outlet right ventricle (HP:0001719)1.69910401
143Congenital malformation of the right heart (HP:0011723)1.69910401
144Abnormality of the intrinsic pathway (HP:0010989)1.69246449
145Amblyopia (HP:0000646)1.68696627
146Turricephaly (HP:0000262)1.67264891
147Excessive salivation (HP:0003781)1.67226493
148Drooling (HP:0002307)1.67226493
149Psychosis (HP:0000709)1.65662359
150Mixed hearing impairment (HP:0000410)1.65565857
151Dysdiadochokinesis (HP:0002075)1.64249658
152Facial shape deformation (HP:0011334)1.64019690
153Potter facies (HP:0002009)1.64019690
154Irritability (HP:0000737)1.63514705
155Type II lissencephaly (HP:0007260)1.61605289
156Hyperphosphaturia (HP:0003109)1.61449755

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR4.41875025
2NTRK33.22804137
3PRKD33.20608914
4MARK13.05694799
5EPHA42.67817211
6PHKG22.31616584
7PHKG12.31616584
8NTRK12.28298126
9MAP3K92.27530632
10NTRK22.24397695
11MAP3K42.03254275
12MINK11.91248800
13UHMK11.84682471
14MAP3K21.82136817
15PASK1.77408601
16BRSK11.77027904
17CASK1.71004781
18TRIB31.69656799
19MAPK131.67061655
20MAP2K71.63145199
21LMTK21.57556875
22TNIK1.54291732
23GRK51.54101210
24MAP2K41.50794623
25MAPK151.49426553
26HIPK21.46615550
27MUSK1.45275677
28DAPK21.42752503
29PRPF4B1.40312629
30PAK61.30051581
31CDK51.27967915
32SIK11.27728404
33KSR21.26727087
34RIPK11.23945098
35CDK191.21395030
36PAK31.19192414
37WNK41.16749407
38CAMKK21.15066296
39SGK2231.13986267
40SGK4941.13986267
41CAMKK11.12538504
42PRKCG1.08612151
43DAPK11.07143802
44MAP3K11.06785668
45PRKCH1.01621869
46RET0.97950783
47CDK11A0.96286492
48CDC42BPA0.94260591
49SIK20.93325809
50ARAF0.93065375
51BCKDK0.91222779
52ADRBK10.89170068
53PRKCE0.88431595
54LATS20.84491053
55PDGFRA0.83742164
56CAMK2A0.83390286
57DYRK1A0.83287430
58NEK60.81465840
59PRKD20.80328388
60CAMK2B0.79755692
61TAOK30.77360954
62WEE10.76855776
63TNK20.76104339
64SGK20.75070542
65KSR10.72098266
66PNCK0.71209110
67PINK10.70754678
68CAMK40.68195278
69CAMK2G0.67402034
70MAPK100.65825602
71NME10.64858107
72DDR20.63216780
73MARK20.62685625
74ALK0.62252515
75MAP3K110.61852992
76IRAK20.61522346
77CAMK2D0.61218998
78MAP2K20.59397753
79PRKACA0.57777470
80MAP2K10.57506975
81CSNK1G20.56782926
82WNK30.56058193
83BRAF0.55282697
84PTK20.55112097
85PRKACG0.54591753
86PRKCZ0.54380286
87DYRK20.53669071
88MAPK120.53196023
89CDK140.53185253
90DAPK30.52700462
91ROCK20.52034873
92SGK30.51797590
93PTK60.50635026
94PKN10.50569559
95STK380.50444572
96TYRO30.49524079
97CAMK1G0.49361588
98FRK0.48081042
99LIMK10.47756957
100SCYL20.47723121
101FES0.46534355
102CDK150.46251058
103STK110.46111254
104CDK180.45862893
105FGFR20.45812784
106WNK10.45126184
107FER0.44628723
108RPS6KA30.44273314
109CAMK10.43330570
110SGK10.42899746
111DYRK1B0.42699409
112PRKAA10.42007886
113CSNK1G30.41857353
114ERN10.41820210
115PDPK10.41244527
116IRAK10.41048191
117PRKCA0.40781157
118PRKD10.40725970
119TSSK60.40586947
120MAPKAPK50.40491628
121ROCK10.39994569
122PLK20.39968725
123CAMK1D0.38983773
124PRKG10.37767538
125ERBB20.37739418
126OXSR10.37547919
127BRSK20.36091351
128CSNK1A1L0.34759272
129RIPK40.33992009
130PRKG20.33614193
131MAPK40.32776570
132CSNK1A10.32227606
133CCNB10.31422004
134CSNK1D0.31259932
135FYN0.30545502

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049504.50805576
2Nitrogen metabolism_Homo sapiens_hsa009103.06697778
3Insulin secretion_Homo sapiens_hsa049112.61465557
4Sulfur metabolism_Homo sapiens_hsa009202.14776766
5Synaptic vesicle cycle_Homo sapiens_hsa047212.10741769
6GABAergic synapse_Homo sapiens_hsa047272.05641444
7Nicotine addiction_Homo sapiens_hsa050332.00606558
8Vitamin B6 metabolism_Homo sapiens_hsa007501.89763009
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.85584218
10Cocaine addiction_Homo sapiens_hsa050301.76321106
11Protein export_Homo sapiens_hsa030601.72158378
12Glutamatergic synapse_Homo sapiens_hsa047241.64677894
13Butanoate metabolism_Homo sapiens_hsa006501.62573730
14Circadian entrainment_Homo sapiens_hsa047131.61618654
15Amphetamine addiction_Homo sapiens_hsa050311.60089925
16Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.59973332
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.58196502
18Taste transduction_Homo sapiens_hsa047421.49151914
19Long-term potentiation_Homo sapiens_hsa047201.46340356
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.46206992
21Type II diabetes mellitus_Homo sapiens_hsa049301.46164289
22Morphine addiction_Homo sapiens_hsa050321.44805293
23Dopaminergic synapse_Homo sapiens_hsa047281.40511112
24Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.35030560
25Cholinergic synapse_Homo sapiens_hsa047251.29273050
26Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.26339724
27Carbohydrate digestion and absorption_Homo sapiens_hsa049731.25089706
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.21796672
29Salivary secretion_Homo sapiens_hsa049701.19034805
30Serotonergic synapse_Homo sapiens_hsa047261.16944253
31Oxidative phosphorylation_Homo sapiens_hsa001901.15628328
32Vibrio cholerae infection_Homo sapiens_hsa051101.15591612
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.11835256
34Gastric acid secretion_Homo sapiens_hsa049711.08348259
35Olfactory transduction_Homo sapiens_hsa047401.07757512
36Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03370597
37Bile secretion_Homo sapiens_hsa049761.02375761
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.02112614
39Alzheimers disease_Homo sapiens_hsa050101.01915348
40Pancreatic secretion_Homo sapiens_hsa049721.01706849
41Fatty acid metabolism_Homo sapiens_hsa012121.00415349
42Tryptophan metabolism_Homo sapiens_hsa003801.00090325
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99956343
44Collecting duct acid secretion_Homo sapiens_hsa049660.96985385
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95992341
46Phosphatidylinositol signaling system_Homo sapiens_hsa040700.94564508
47Cardiac muscle contraction_Homo sapiens_hsa042600.93951937
48Arginine biosynthesis_Homo sapiens_hsa002200.93664687
49Fatty acid degradation_Homo sapiens_hsa000710.92642918
50Long-term depression_Homo sapiens_hsa047300.92021634
51Type I diabetes mellitus_Homo sapiens_hsa049400.91716740
52Parkinsons disease_Homo sapiens_hsa050120.89625800
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87737053
54Glucagon signaling pathway_Homo sapiens_hsa049220.87595489
55Renin secretion_Homo sapiens_hsa049240.85465962
56Prion diseases_Homo sapiens_hsa050200.84899623
57Fatty acid biosynthesis_Homo sapiens_hsa000610.84203423
58Oocyte meiosis_Homo sapiens_hsa041140.83630202
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82513918
60Thyroid hormone synthesis_Homo sapiens_hsa049180.82364719
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.82349660
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81818166
63Gap junction_Homo sapiens_hsa045400.81236796
64Glioma_Homo sapiens_hsa052140.80835697
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.80617811
66Arginine and proline metabolism_Homo sapiens_hsa003300.80153025
67Fatty acid elongation_Homo sapiens_hsa000620.79551291
68Phototransduction_Homo sapiens_hsa047440.79139818
69Calcium signaling pathway_Homo sapiens_hsa040200.77509958
70Melanogenesis_Homo sapiens_hsa049160.77009233
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.75710952
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.75113788
73ErbB signaling pathway_Homo sapiens_hsa040120.72219697
74Phenylalanine metabolism_Homo sapiens_hsa003600.71736829
75Estrogen signaling pathway_Homo sapiens_hsa049150.70866770
76cAMP signaling pathway_Homo sapiens_hsa040240.66552982
77Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.65776911
78beta-Alanine metabolism_Homo sapiens_hsa004100.64829589
79Steroid biosynthesis_Homo sapiens_hsa001000.64609144
80Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64405831
81GnRH signaling pathway_Homo sapiens_hsa049120.63205396
82Dorso-ventral axis formation_Homo sapiens_hsa043200.60783030
83MAPK signaling pathway_Homo sapiens_hsa040100.60114171
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59242595
85Rap1 signaling pathway_Homo sapiens_hsa040150.58809252
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.58809068
87Inositol phosphate metabolism_Homo sapiens_hsa005620.58135078
88PPAR signaling pathway_Homo sapiens_hsa033200.57676556
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57210666
90Ras signaling pathway_Homo sapiens_hsa040140.57063968
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57051174
92Tyrosine metabolism_Homo sapiens_hsa003500.56186569
93Oxytocin signaling pathway_Homo sapiens_hsa049210.54682206
94Circadian rhythm_Homo sapiens_hsa047100.54106392
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52670481
96Histidine metabolism_Homo sapiens_hsa003400.52120493
97N-Glycan biosynthesis_Homo sapiens_hsa005100.52069436
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51159095
99Propanoate metabolism_Homo sapiens_hsa006400.50434958
100Starch and sucrose metabolism_Homo sapiens_hsa005000.49812538
101Wnt signaling pathway_Homo sapiens_hsa043100.49488101
102Alcoholism_Homo sapiens_hsa050340.49231134
103SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48999291
104Axon guidance_Homo sapiens_hsa043600.48746052
105Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.47206879
106Fat digestion and absorption_Homo sapiens_hsa049750.46439367
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.46379040
108Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46207921
109Galactose metabolism_Homo sapiens_hsa000520.46073258
110Choline metabolism in cancer_Homo sapiens_hsa052310.45355205
111ABC transporters_Homo sapiens_hsa020100.44952304
112Regulation of autophagy_Homo sapiens_hsa041400.44933853
113Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44886526
114Insulin resistance_Homo sapiens_hsa049310.44343869
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.43933279
116Insulin signaling pathway_Homo sapiens_hsa049100.42977058
117Endocytosis_Homo sapiens_hsa041440.40838224
118Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.39968712
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39695400
120Dilated cardiomyopathy_Homo sapiens_hsa054140.38476589
121Peroxisome_Homo sapiens_hsa041460.38251150
122Selenocompound metabolism_Homo sapiens_hsa004500.37837883
123Huntingtons disease_Homo sapiens_hsa050160.37615166
124Pyruvate metabolism_Homo sapiens_hsa006200.37435952
125Folate biosynthesis_Homo sapiens_hsa007900.35082795
126VEGF signaling pathway_Homo sapiens_hsa043700.34935918
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.34849633
128Hippo signaling pathway_Homo sapiens_hsa043900.32984649
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27346734
130Mineral absorption_Homo sapiens_hsa049780.25244622
131AMPK signaling pathway_Homo sapiens_hsa041520.23450051
132Tight junction_Homo sapiens_hsa045300.20458768
133Longevity regulating pathway - mammal_Homo sapiens_hsa042110.18353069

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