ENO4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.89315971
2axoneme assembly (GO:0035082)9.88666846
3motile cilium assembly (GO:0044458)9.74965384
4ventricular system development (GO:0021591)9.59036463
5sperm motility (GO:0030317)8.40837752
6GTP biosynthetic process (GO:0006183)8.13177302
7regulation of cilium movement (GO:0003352)7.37676351
8fusion of sperm to egg plasma membrane (GO:0007342)7.32307649
9nucleoside diphosphate phosphorylation (GO:0006165)7.26416697
10UTP biosynthetic process (GO:0006228)7.15539563
11acrosome reaction (GO:0007340)7.02869724
12UTP metabolic process (GO:0046051)6.53194681
13sperm-egg recognition (GO:0035036)6.50786207
14acrosome assembly (GO:0001675)6.46349421
15spermatid development (GO:0007286)6.43610653
16left/right axis specification (GO:0070986)6.28973662
17multicellular organism reproduction (GO:0032504)6.26282021
18retinal rod cell development (GO:0046548)6.18405255
19intraciliary transport (GO:0042073)6.15473831
20binding of sperm to zona pellucida (GO:0007339)6.14532058
21retinal cone cell development (GO:0046549)6.07805165
22piRNA metabolic process (GO:0034587)5.99573410
23cell wall macromolecule catabolic process (GO:0016998)5.94037215
24cell wall macromolecule metabolic process (GO:0044036)5.94037215
25cell-cell recognition (GO:0009988)5.76630658
26plasma membrane fusion (GO:0045026)5.59167342
27cilium organization (GO:0044782)5.44572509
28guanosine-containing compound biosynthetic process (GO:1901070)5.40081013
29CTP metabolic process (GO:0046036)5.27887347
30CTP biosynthetic process (GO:0006241)5.27887347
31male meiosis (GO:0007140)5.27573457
32single fertilization (GO:0007338)5.27145315
33microtubule severing (GO:0051013)5.26203947
34cilium morphogenesis (GO:0060271)5.19118710
35reproduction (GO:0000003)5.18554018
36pyrimidine nucleobase catabolic process (GO:0006208)5.18123756
37cilium assembly (GO:0042384)5.16607438
38negative regulation of inclusion body assembly (GO:0090084)5.03411445
39synaptonemal complex organization (GO:0070193)4.97302820
40protein localization to cilium (GO:0061512)4.95667461
41microtubule bundle formation (GO:0001578)4.93963540
42pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.75305669
43fertilization (GO:0009566)4.57017883
44regulation of microtubule-based movement (GO:0060632)4.54247328
45cellular component assembly involved in morphogenesis (GO:0010927)4.53937136
46microtubule-based movement (GO:0007018)4.53281206
47pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.43561626
48spermatogenesis (GO:0007283)4.41740581
49male gamete generation (GO:0048232)4.39650773
50male meiosis I (GO:0007141)4.27396204
51left/right pattern formation (GO:0060972)4.21385390
52regulation of inclusion body assembly (GO:0090083)4.11002886
53sperm capacitation (GO:0048240)4.08373732
54gamete generation (GO:0007276)4.07711725
55nucleotide phosphorylation (GO:0046939)4.07326589
56nonmotile primary cilium assembly (GO:0035058)4.03898879
57pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.03880770
58synaptonemal complex assembly (GO:0007130)4.03233898
59nucleobase catabolic process (GO:0046113)3.99846349
60photoreceptor cell maintenance (GO:0045494)3.94257761
61calcium ion-dependent exocytosis (GO:0017156)3.88879110
62DNA methylation involved in gamete generation (GO:0043046)3.84828776
63presynaptic membrane assembly (GO:0097105)3.74451255
64protein polyglutamylation (GO:0018095)3.71525356
65meiotic cell cycle (GO:0051321)3.63664778
66germ cell development (GO:0007281)3.63050948
67cell projection assembly (GO:0030031)3.56762112
68pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.49071188
69nucleoside diphosphate metabolic process (GO:0009132)3.39429712
70cellular process involved in reproduction in multicellular organism (GO:0022412)3.35302494
71meiosis I (GO:0007127)3.33176531
72photoreceptor cell development (GO:0042461)3.27178912
73cell recognition (GO:0008037)3.25280538
74multicellular organismal reproductive process (GO:0048609)3.20836847
75eye photoreceptor cell development (GO:0042462)3.20390698
76behavioral response to nicotine (GO:0035095)3.18202483
77presynaptic membrane organization (GO:0097090)3.14981527
78specification of symmetry (GO:0009799)3.10009378
79ubiquinone biosynthetic process (GO:0006744)3.09598209
80neural tube formation (GO:0001841)3.08574140
81spermatid nucleus differentiation (GO:0007289)3.08282808
82meiotic nuclear division (GO:0007126)3.03530123
83one-carbon compound transport (GO:0019755)3.02574124
84microtubule depolymerization (GO:0007019)2.97933645
85organic cation transport (GO:0015695)2.97714114
86ubiquinone metabolic process (GO:0006743)2.97672772
87positive regulation of action potential (GO:0045760)2.94868928
88centriole assembly (GO:0098534)2.89819811
89chaperone-mediated protein complex assembly (GO:0051131)2.87623636
90pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.85840140
91vocalization behavior (GO:0071625)2.85672257
92retinal ganglion cell axon guidance (GO:0031290)2.84042379
93chromosome organization involved in meiosis (GO:0070192)2.83856582
94resolution of meiotic recombination intermediates (GO:0000712)2.82921217
95positive regulation of meiosis (GO:0045836)2.81745903
96sensory perception of smell (GO:0007608)2.79075306
97calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.79027224
98pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.76444426
99centriole replication (GO:0007099)2.71463717
100purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.71189168
101neuron recognition (GO:0008038)2.69375284
102regulation of meiosis I (GO:0060631)2.69275934
103postsynaptic membrane organization (GO:0001941)2.68597831
104smoothened signaling pathway (GO:0007224)2.67938243
105axon ensheathment in central nervous system (GO:0032291)2.65556777
106central nervous system myelination (GO:0022010)2.65556777
107positive regulation of meiotic cell cycle (GO:0051446)2.65414237
108microtubule polymerization or depolymerization (GO:0031109)2.64257145
109DNA integration (GO:0015074)2.63935190
110response to pheromone (GO:0019236)2.63803038
111regulation of feeding behavior (GO:0060259)2.63674580
112regulation of action potential (GO:0098900)2.62261700
113neuron cell-cell adhesion (GO:0007158)2.61559064
114purine nucleoside triphosphate biosynthetic process (GO:0009145)2.60241325
115quinone biosynthetic process (GO:1901663)2.52588333
116pyrimidine ribonucleotide metabolic process (GO:0009218)2.49996940
117seminiferous tubule development (GO:0072520)2.49891523
118organelle assembly (GO:0070925)2.48088859
119microtubule-based process (GO:0007017)2.46200683
120determination of left/right symmetry (GO:0007368)2.45784977
121regulation of macrophage chemotaxis (GO:0010758)2.45331535
122microtubule-based transport (GO:0010970)2.45287368
123brain morphogenesis (GO:0048854)2.44490996
124regulation of mononuclear cell migration (GO:0071675)2.43086270
125synapse assembly (GO:0007416)2.42749897
126fucose catabolic process (GO:0019317)2.42533956
127L-fucose metabolic process (GO:0042354)2.42533956
128L-fucose catabolic process (GO:0042355)2.42533956
129protein refolding (GO:0042026)2.42104308
130determination of bilateral symmetry (GO:0009855)2.39991149
131negative regulation of axon guidance (GO:1902668)2.36792085
132lateral ventricle development (GO:0021670)2.36706412
133striatum development (GO:0021756)2.35704257
134homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.33143275
135limb bud formation (GO:0060174)2.31543751
136cytoskeleton-dependent intracellular transport (GO:0030705)2.31234141
137regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.30691270
138anterograde synaptic vesicle transport (GO:0048490)2.28244378
139appendage development (GO:0048736)2.25673014
140limb development (GO:0060173)2.25673014
141central nervous system neuron axonogenesis (GO:0021955)2.25083106
142olfactory bulb development (GO:0021772)2.24773060
143establishment of planar polarity (GO:0001736)2.21580528
144establishment of tissue polarity (GO:0007164)2.21580528
145lateral sprouting from an epithelium (GO:0060601)2.21398697
146establishment of protein localization to Golgi (GO:0072600)2.19889705
147epithelial cell differentiation involved in kidney development (GO:0035850)2.19328519
148negative regulation of transcription regulatory region DNA binding (GO:2000678)2.18978130
149kidney morphogenesis (GO:0060993)2.17311606
150cornea development in camera-type eye (GO:0061303)2.16706142
151negative regulation of appetite (GO:0032099)2.15537694
152negative regulation of response to food (GO:0032096)2.15537694
153regulation of collateral sprouting (GO:0048670)2.12881222
154anterograde axon cargo transport (GO:0008089)2.12869467
155protein localization to Golgi apparatus (GO:0034067)2.12721081
156tongue development (GO:0043586)2.10329742
157glycosphingolipid biosynthetic process (GO:0006688)2.10043913
158neurotransmitter catabolic process (GO:0042135)2.09825309
159spinal cord motor neuron differentiation (GO:0021522)2.09718533
160neuron fate determination (GO:0048664)2.08400888
161axonemal dynein complex assembly (GO:0070286)14.3844111
162cilium movement (GO:0003341)14.2486170
163cilium or flagellum-dependent cell motility (GO:0001539)13.8194379
164epithelial cilium movement (GO:0003351)12.3908389

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.71635856
2EZH2_22144423_ChIP-Seq_EOC_Human4.71183042
3IGF1R_20145208_ChIP-Seq_DFB_Human3.87809349
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.40421701
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.21554088
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.18870658
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.93735601
8CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.45517666
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.14707090
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.02220544
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.01940764
12EWS_26573619_Chip-Seq_HEK293_Human1.99879952
13GATA1_26923725_Chip-Seq_HPCs_Mouse1.95405031
14VDR_22108803_ChIP-Seq_LS180_Human1.95249496
15CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95024085
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.92340412
17GBX2_23144817_ChIP-Seq_PC3_Human1.90729615
18PCGF2_27294783_Chip-Seq_ESCs_Mouse1.88780845
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.78279172
20PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.74482134
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74121825
22TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.72382554
23POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.72382554
24TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.68012645
25SUZ12_27294783_Chip-Seq_NPCs_Mouse1.65046971
26AR_21572438_ChIP-Seq_LNCaP_Human1.64460325
27PCGF2_27294783_Chip-Seq_NPCs_Mouse1.63385455
28REST_21632747_ChIP-Seq_MESCs_Mouse1.63120061
29SMAD4_21799915_ChIP-Seq_A2780_Human1.63027183
30* RNF2_27304074_Chip-Seq_NSC_Mouse1.60320986
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.59811803
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.59626020
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.58565301
34EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.56785454
35TAF15_26573619_Chip-Seq_HEK293_Human1.56602306
36TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56391924
37NFE2_27457419_Chip-Seq_LIVER_Mouse1.52654374
38AR_25329375_ChIP-Seq_VCAP_Human1.51551742
39UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.51329583
40MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.49071743
41ER_23166858_ChIP-Seq_MCF-7_Human1.47027359
42KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.46706868
43RUNX2_22187159_ChIP-Seq_PCA_Human1.46345413
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.46106837
45NANOG_18555785_Chip-Seq_ESCs_Mouse1.46011956
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45691510
47P300_19829295_ChIP-Seq_ESCs_Human1.45160315
48TAL1_26923725_Chip-Seq_HPCs_Mouse1.42355999
49* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38873675
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38404056
51KLF5_20875108_ChIP-Seq_MESCs_Mouse1.36610516
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36539653
53TCF4_22108803_ChIP-Seq_LS180_Human1.33732247
54P53_22387025_ChIP-Seq_ESCs_Mouse1.33566935
55E2F1_18555785_Chip-Seq_ESCs_Mouse1.32843700
56CMYC_18555785_Chip-Seq_ESCs_Mouse1.32031085
57* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.31933446
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.30317739
59CBP_20019798_ChIP-Seq_JUKART_Human1.30056416
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30056416
61CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29822958
62FUS_26573619_Chip-Seq_HEK293_Human1.29795022
63STAT3_18555785_Chip-Seq_ESCs_Mouse1.28629415
64P300_18555785_Chip-Seq_ESCs_Mouse1.28561536
65SUZ12_18555785_Chip-Seq_ESCs_Mouse1.28435143
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27348931
67EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.27104780
68FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.26867195
69ZNF274_21170338_ChIP-Seq_K562_Hela1.26846688
70HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.26713713
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26099103
72TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25956679
73TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.24806061
74DROSHA_22980978_ChIP-Seq_HELA_Human1.23981057
75OCT4_18555785_Chip-Seq_ESCs_Mouse1.22765379
76EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21449414
77CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.21090824
78ELK4_26923725_Chip-Seq_MESODERM_Mouse1.20930623
79SOX2_18555785_Chip-Seq_ESCs_Mouse1.20265441
80SMAD4_21741376_ChIP-Seq_EPCs_Human1.20003584
81BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19590858
82EZH2_27294783_Chip-Seq_ESCs_Mouse1.18875136
83WDR5_24793694_ChIP-Seq_LNCAP_Human1.18869687
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18705052
85EED_16625203_ChIP-ChIP_MESCs_Mouse1.18615109
86RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.18469202
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17794074
88ZFX_18555785_Chip-Seq_ESCs_Mouse1.16766139
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.16717169
90STAT3_23295773_ChIP-Seq_U87_Human1.16399403
91CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.16303336
92TCF4_23295773_ChIP-Seq_U87_Human1.16235344
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.15069758
94SOX2_21211035_ChIP-Seq_LN229_Gbm1.14517505
95FOXM1_26456572_ChIP-Seq_MCF-7_Human1.13548192
96EZH2_27294783_Chip-Seq_NPCs_Mouse1.13015892
97SUZ12_27294783_Chip-Seq_ESCs_Mouse1.12923314
98SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.12562657
99SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.12547408
100PU1_27457419_Chip-Seq_LIVER_Mouse1.12069207
101TP53_22573176_ChIP-Seq_HFKS_Human1.11996671
102CRX_20693478_ChIP-Seq_RETINA_Mouse1.11670042
103KLF4_18555785_Chip-Seq_ESCs_Mouse1.11584655
104BCAT_22108803_ChIP-Seq_LS180_Human1.11448714
105NANOG_19829295_ChIP-Seq_ESCs_Human1.11091718
106SOX2_19829295_ChIP-Seq_ESCs_Human1.11091718
107ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11035586
108SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.10966652
109HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10390246
110RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08890905
111KAP1_22055183_ChIP-Seq_ESCs_Mouse1.08460789
112RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.08186929
113* KDM2B_26808549_Chip-Seq_REH_Human1.08140374
114TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08027127
115AHR_22903824_ChIP-Seq_MCF-7_Human1.07478105
116LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06028321
117STAT1_17558387_ChIP-Seq_HELA_Human1.06006578
118CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05815236
119CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04247361
120FLI1_21867929_ChIP-Seq_TH2_Mouse1.04116254
121NMYC_18555785_Chip-Seq_ESCs_Mouse1.03836216
122PIAS1_25552417_ChIP-Seq_VCAP_Human1.03679819
123SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03091949
124TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03081120
125SOX9_26525672_Chip-Seq_HEART_Mouse1.02717860
126TBL1_22424771_ChIP-Seq_293T_Human1.01834404
127PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01576688
128TP53_18474530_ChIP-ChIP_U2OS_Human1.01499318
129CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01233655
130GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00753889
131OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00109345
132PRDM14_20953172_ChIP-Seq_ESCs_Human0.99746324
133SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99254997
134SOX2_22085726_ChIP-Seq_NPCs_Mouse0.98758721
135AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98274850
136CTCF_18555785_Chip-Seq_ESCs_Mouse0.98107709
137JUN_21703547_ChIP-Seq_K562_Human0.96190106
138EZH2_27304074_Chip-Seq_ESCs_Mouse0.94840448
139P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91776687
140* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.91547859

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.83856592
2MP0002653_abnormal_ependyma_morphology4.44853161
3MP0001984_abnormal_olfaction4.29040463
4MP0003698_abnormal_male_reproductive3.94462238
5MP0003136_yellow_coat_color3.59273636
6MP0001929_abnormal_gametogenesis3.48687115
7MP0005623_abnormal_meninges_morphology3.41779524
8MP0008004_abnormal_stomach_pH3.07553886
9MP0008877_abnormal_DNA_methylation2.94729262
10MP0003122_maternal_imprinting2.81535142
11MP0005646_abnormal_pituitary_gland2.57140292
12MP0009046_muscle_twitch2.49272953
13MP0002210_abnormal_sex_determination2.45972219
14MP0002160_abnormal_reproductive_system2.42716791
15MP0003880_abnormal_central_pattern2.16978885
16MP0002161_abnormal_fertility/fecundity2.09862493
17MP0001440_abnormal_grooming_behavior2.07768150
18MP0004133_heterotaxia1.95224504
19MP0001145_abnormal_male_reproductive1.92682999
20MP0002736_abnormal_nociception_after1.83495013
21MP0004859_abnormal_synaptic_plasticity1.72393327
22MP0000653_abnormal_sex_gland1.72016219
23MP0001485_abnormal_pinna_reflex1.71707336
24MP0000516_abnormal_urinary_system1.71272386
25MP0005367_renal/urinary_system_phenotyp1.71272386
26MP0001529_abnormal_vocalization1.71120568
27MP0003121_genomic_imprinting1.64083172
28MP0001968_abnormal_touch/_nociception1.62921051
29MP0004270_analgesia1.59845794
30MP0006292_abnormal_olfactory_placode1.57314607
31MP0009745_abnormal_behavioral_response1.55615958
32MP0006072_abnormal_retinal_apoptosis1.54670292
33MP0003690_abnormal_glial_cell1.52238432
34MP0003635_abnormal_synaptic_transmissio1.50883335
35MP0000566_synostosis1.49757802
36MP0002572_abnormal_emotion/affect_behav1.47291958
37MP0002909_abnormal_adrenal_gland1.47229337
38MP0004742_abnormal_vestibular_system1.46964393
39MP0005551_abnormal_eye_electrophysiolog1.46025899
40MP0002064_seizures1.45509409
41MP0008875_abnormal_xenobiotic_pharmacok1.43521535
42MP0002282_abnormal_trachea_morphology1.42473221
43MP0005389_reproductive_system_phenotype1.41073181
44MP0002734_abnormal_mechanical_nocicepti1.40043914
45MP0000778_abnormal_nervous_system1.40028179
46MP0004043_abnormal_pH_regulation1.38353718
47MP0001501_abnormal_sleep_pattern1.32942925
48MP0002938_white_spotting1.32766364
49MP0002272_abnormal_nervous_system1.32096068
50MP0010386_abnormal_urinary_bladder1.31081710
51MP0002063_abnormal_learning/memory/cond1.30518787
52MP0005248_abnormal_Harderian_gland1.30314212
53MP0001486_abnormal_startle_reflex1.27554817
54MP0003634_abnormal_glial_cell1.26803122
55MP0005423_abnormal_somatic_nervous1.26326688
56MP0001346_abnormal_lacrimal_gland1.25342190
57MP0002751_abnormal_autonomic_nervous1.22540941
58MP0002234_abnormal_pharynx_morphology1.20153229
59MP0002557_abnormal_social/conspecific_i1.18262131
60MP0000569_abnormal_digit_pigmentation1.16586981
61MP0004858_abnormal_nervous_system1.15885728
62MP0000427_abnormal_hair_cycle1.14986002
63MP0002928_abnormal_bile_duct1.14865600
64MP0003119_abnormal_digestive_system1.13406915
65MP0003950_abnormal_plasma_membrane1.10954645
66MP0001293_anophthalmia1.10359533
67MP0005499_abnormal_olfactory_system1.09649033
68MP0005394_taste/olfaction_phenotype1.09649033
69MP0002233_abnormal_nose_morphology1.08651977
70MP0006276_abnormal_autonomic_nervous1.06802324
71MP0002067_abnormal_sensory_capabilities1.06235832
72MP0001324_abnormal_eye_pigmentation1.02402097
73MP0008995_early_reproductive_senescence0.98317455
74MP0010030_abnormal_orbit_morphology0.97924965
75MP0005253_abnormal_eye_physiology0.96687734
76MP0000383_abnormal_hair_follicle0.94306792
77MP0002735_abnormal_chemical_nociception0.93282706
78MP0002882_abnormal_neuron_morphology0.93252553
79MP0003890_abnormal_embryonic-extraembry0.93007823
80MP0001661_extended_life_span0.92310643
81MP0005645_abnormal_hypothalamus_physiol0.91113735
82MP0002752_abnormal_somatic_nervous0.90796414
83MP0002152_abnormal_brain_morphology0.89067622
84MP0002822_catalepsy0.87660814
85MP0001177_atelectasis0.87656852
86MP0003942_abnormal_urinary_system0.87541589
87MP0003938_abnormal_ear_development0.87164619
88MP0003633_abnormal_nervous_system0.86544734
89MP0001502_abnormal_circadian_rhythm0.85343059
90MP0000049_abnormal_middle_ear0.84722598
91MP0004142_abnormal_muscle_tone0.83678984
92MP0005670_abnormal_white_adipose0.82496282
93MP0002184_abnormal_innervation0.82201949
94MP0001188_hyperpigmentation0.82130893
95MP0008789_abnormal_olfactory_epithelium0.80349223
96MP0003631_nervous_system_phenotype0.78941214
97MP0003755_abnormal_palate_morphology0.78132781
98MP0004885_abnormal_endolymph0.77648682
99MP0001970_abnormal_pain_threshold0.77588053
100MP0001286_abnormal_eye_development0.77320231
101MP0000920_abnormal_myelination0.76587846
102MP0002133_abnormal_respiratory_system0.76258937
103MP0005388_respiratory_system_phenotype0.76258937
104MP0003329_amyloid_beta_deposits0.75955002
105MP0000631_abnormal_neuroendocrine_gland0.75610523
106MP0002102_abnormal_ear_morphology0.75155386
107MP0003787_abnormal_imprinting0.74611379
108MP0002229_neurodegeneration0.74107061
109MP0001986_abnormal_taste_sensitivity0.73643225
110MP0004811_abnormal_neuron_physiology0.73218264
111MP0001963_abnormal_hearing_physiology0.72508755
112MP0005379_endocrine/exocrine_gland_phen0.71656063
113MP0003632_abnormal_nervous_system0.70925386
114MP0003861_abnormal_nervous_system0.70576738
115MP0005647_abnormal_sex_gland0.68977628
116MP0002733_abnormal_thermal_nociception0.68539767
117MP0000026_abnormal_inner_ear0.66695162
118MP0002066_abnormal_motor_capabilities/c0.66425310
119MP0000955_abnormal_spinal_cord0.65854556
120MP0003878_abnormal_ear_physiology0.65711353
121MP0005377_hearing/vestibular/ear_phenot0.65711353
122MP0003011_delayed_dark_adaptation0.62469683
123MP0005195_abnormal_posterior_eye0.61978983
124MP0002277_abnormal_respiratory_mucosa0.61866345
125MP0001905_abnormal_dopamine_level0.61365312
126MP0003937_abnormal_limbs/digits/tail_de0.61078135
127MP0004782_abnormal_surfactant_physiolog0.60490133
128MP0005391_vision/eye_phenotype0.58979738
129MP0002168_other_aberrant_phenotype0.58303315
130MP0002638_abnormal_pupillary_reflex0.57181743
131MP0001765_abnormal_ion_homeostasis0.56898520
132MP0002132_abnormal_respiratory_system0.56336791

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.66632132
2Absent/shortened dynein arms (HP:0200106)9.46624116
3Dynein arm defect of respiratory motile cilia (HP:0012255)9.46624116
4Abnormal respiratory motile cilium morphology (HP:0005938)9.00541819
5Abnormal respiratory epithelium morphology (HP:0012253)9.00541819
6Chronic bronchitis (HP:0004469)7.78007108
7Bronchiectasis (HP:0002110)5.15933134
8Nasal polyposis (HP:0100582)4.74402216
9Infertility (HP:0000789)4.00266766
10Abnormality of the nasal mucosa (HP:0000433)3.84242455
11Nephronophthisis (HP:0000090)3.83949839
12Bronchitis (HP:0012387)3.77419662
13Pancreatic fibrosis (HP:0100732)3.69336925
14True hermaphroditism (HP:0010459)3.66943325
15Tubulointerstitial nephritis (HP:0001970)3.66479932
16Absent rod-and cone-mediated responses on ERG (HP:0007688)3.57502209
17Medial flaring of the eyebrow (HP:0010747)3.48286546
18Recurrent sinusitis (HP:0011108)3.31628352
19Abnormality of midbrain morphology (HP:0002418)3.11533491
20Molar tooth sign on MRI (HP:0002419)3.11533491
21Abnormal biliary tract physiology (HP:0012439)2.99280923
22Bile duct proliferation (HP:0001408)2.99280923
23Abnormality of the renal medulla (HP:0100957)2.96288692
24Gait imbalance (HP:0002141)2.93451624
25Tubular atrophy (HP:0000092)2.90471698
26Congenital primary aphakia (HP:0007707)2.89030717
27Pancreatic cysts (HP:0001737)2.85412171
28Recurrent otitis media (HP:0000403)2.79030156
29Postaxial foot polydactyly (HP:0001830)2.77837509
30Abnormal rod and cone electroretinograms (HP:0008323)2.73486678
31Cystic liver disease (HP:0006706)2.63851190
32Abnormality of dentin (HP:0010299)2.57952366
33Occipital encephalocele (HP:0002085)2.57474168
34Nephrogenic diabetes insipidus (HP:0009806)2.57061225
35Hyperglycinemia (HP:0002154)2.51994316
36Male infertility (HP:0003251)2.48607311
37Median cleft lip (HP:0000161)2.47156930
38Supernumerary spleens (HP:0009799)2.46886028
39Chronic sinusitis (HP:0011109)2.46144719
40Chronic hepatic failure (HP:0100626)2.44444042
41Genital tract atresia (HP:0001827)2.40478933
42Bony spicule pigmentary retinopathy (HP:0007737)2.34746699
43Aplasia/Hypoplasia of the tongue (HP:0010295)2.32641352
44Congenital hepatic fibrosis (HP:0002612)2.32346595
45Tubulointerstitial abnormality (HP:0001969)2.28679760
46Stage 5 chronic kidney disease (HP:0003774)2.26121624
47Vaginal atresia (HP:0000148)2.25959619
48Poor coordination (HP:0002370)2.15292077
49Abnormality of the dental root (HP:0006486)2.08274032
50Taurodontia (HP:0000679)2.08274032
51Abnormality of permanent molar morphology (HP:0011071)2.08274032
52Postaxial hand polydactyly (HP:0001162)2.08199765
53Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.7648832
54Abnormal respiratory motile cilium physiology (HP:0012261)11.3904376
55Abnormal ciliary motility (HP:0012262)10.0135638
56Polydipsia (HP:0001959)1.96619606
57Abnormal drinking behavior (HP:0030082)1.96619606
58Abnormality of molar morphology (HP:0011070)1.96384487
59Abnormality of molar (HP:0011077)1.96384487
60Broad distal phalanx of finger (HP:0009836)1.96243325
61Polyphagia (HP:0002591)1.93657067
62Male pseudohermaphroditism (HP:0000037)1.93193024
63Oculomotor apraxia (HP:0000657)1.92887481
64Anencephaly (HP:0002323)1.92587106
65Abnormality of the dental pulp (HP:0006479)1.91474484
66Fibular hypoplasia (HP:0003038)1.90666866
67Narrow forehead (HP:0000341)1.88268914
68Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.88141070
69Degeneration of the lateral corticospinal tracts (HP:0002314)1.88141070
70Gonadotropin excess (HP:0000837)1.84354344
71Aplasia/Hypoplasia of the lens (HP:0008063)1.82264727
72Sclerocornea (HP:0000647)1.81001181
73Abnormality of the renal cortex (HP:0011035)1.80192554
74Facial cleft (HP:0002006)1.78136756
75Preaxial hand polydactyly (HP:0001177)1.77071168
76Abnormality of the labia minora (HP:0012880)1.76247906
77Abdominal situs inversus (HP:0003363)1.74338036
78Abnormality of abdominal situs (HP:0011620)1.74338036
79Drooling (HP:0002307)1.73504902
80Prominent nasal bridge (HP:0000426)1.68549546
81Anophthalmia (HP:0000528)1.66787030
82Abolished electroretinogram (ERG) (HP:0000550)1.66780783
83Hyperactive renin-angiotensin system (HP:0000841)1.61846998
84Decreased testicular size (HP:0008734)1.61137265
85Multicystic kidney dysplasia (HP:0000003)1.56430708
86Excessive salivation (HP:0003781)1.52840966
87Hemiparesis (HP:0001269)1.52514750
88Broad-based gait (HP:0002136)1.52412734
89Cone-rod dystrophy (HP:0000548)1.48820691
90Retinal dysplasia (HP:0007973)1.46937124
91Sex reversal (HP:0012245)1.45687578
92Abnormal sex determination (HP:0012244)1.45687578
93Poor suck (HP:0002033)1.45501310
94Scrotal hypoplasia (HP:0000046)1.45337071
95Hip dysplasia (HP:0001385)1.43913035
96Micropenis (HP:0000054)1.43815599
97Absent speech (HP:0001344)1.43374239
98Focal motor seizures (HP:0011153)1.43171928
99Short nail (HP:0001799)1.42976726
100Hyperventilation (HP:0002883)1.42829332
101Abnormal hair whorl (HP:0010721)1.42633307
102Short foot (HP:0001773)1.42084214
103Bifid tongue (HP:0010297)1.41492973
104Decreased central vision (HP:0007663)1.38981161
105Nephropathy (HP:0000112)1.38598577
106Focal seizures (HP:0007359)1.38478800
107Lissencephaly (HP:0001339)1.37858661
108Abnormality of the corticospinal tract (HP:0002492)1.37568042
109Hyperglycinuria (HP:0003108)1.37145013
110Asthma (HP:0002099)1.35757253
111Bell-shaped thorax (HP:0001591)1.35484084
112Specific learning disability (HP:0001328)1.35358834
113Tubulointerstitial fibrosis (HP:0005576)1.34628891
114Labial hypoplasia (HP:0000066)1.34190910
115Broad foot (HP:0001769)1.33839451
116Microglossia (HP:0000171)1.33680432
117Abnormal connection of the cardiac segments (HP:0011545)1.33253936
118Abnormal ventriculo-arterial connection (HP:0011563)1.33253936
119Transposition of the great arteries (HP:0001669)1.33253936
120Abnormality of renal excretion (HP:0011036)1.30430919
121Aplasia/Hypoplasia of the fibula (HP:0006492)1.28041648
122Retinitis pigmentosa (HP:0000510)1.24714639
123Hypodontia (HP:0000668)1.21658367
124Abnormal umbilical cord blood vessels (HP:0011403)1.19512481
125Single umbilical artery (HP:0001195)1.19512481
126Abnormality of the fetal cardiovascular system (HP:0010948)1.19512481
127Insidious onset (HP:0003587)1.19265382
128Termporal pattern (HP:0011008)1.19265382
129Asplenia (HP:0001746)1.17121886
130Dyschromatopsia (HP:0007641)1.16773422
131Hypotelorism (HP:0000601)1.16232916
132Furrowed tongue (HP:0000221)1.16049636
133Dental crowding (HP:0000678)1.15549770
134Polyuria (HP:0000103)1.14242829
135Aganglionic megacolon (HP:0002251)1.14203035

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK35.71176789
2PDK45.71176789
3PNCK5.27356995
4MAPK154.78365552
5PRKD34.23529100
6PDK23.60790215
7FRK3.41665972
8TESK13.31764089
9MAP4K23.26958295
10TRIM282.54513911
11WNK32.42729800
12STK392.33215721
13MST42.30463243
14ICK2.27224267
15BCKDK1.96899318
16NTRK21.93636008
17PTK2B1.86638545
18WNK41.68431873
19GRK11.63647233
20TNIK1.61145522
21CASK1.56548326
22RPS6KA41.49009816
23CSNK1G11.42969209
24CSNK1A1L1.42532875
25CSNK1G31.41835318
26DAPK21.41212602
27DYRK21.38777951
28CSNK1G21.38313358
29IRAK21.31974250
30WNK11.25348404
31TLK11.23845663
32OXSR11.20876766
33FGFR21.19770494
34FER1.07151126
35TYRO31.06305101
36MAP2K71.04515275
37UHMK11.03194812
38WEE11.01247146
39RIPK41.00749151
40MAPK131.00576881
41STK380.99858934
42AKT30.99653522
43ZAK0.98873537
44PRKCG0.98253276
45NEK60.96592456
46CDK30.93382402
47IRAK10.92829276
48EPHA30.91145696
49PLK20.87082830
50EPHA40.86458975
51TSSK60.84870625
52BMPR20.79915045
53SGK4940.77768392
54SGK2230.77768392
55MAP3K40.77656054
56MAP2K40.76050829
57BCR0.72002282
58BLK0.69887743
59CAMK2A0.69641077
60RPS6KA50.68219226
61MKNK10.67571533
62STK38L0.66729743
63NUAK10.66728693
64NTRK30.65963599
65BRD40.65916941
66PRPF4B0.64015114
67SRPK10.63757828
68MARK10.62514668
69PLK40.62468542
70INSRR0.61702372
71CAMK10.60775427
72CSNK1A10.60566052
73PLK10.60565775
74DYRK1B0.60440782
75CAMK2B0.59803346
76CDK80.58931071
77MUSK0.58693923
78SGK20.58512746
79PHKG20.56835406
80PHKG10.56835406
81CDK190.55757587
82PDK10.53748047
83ADRBK20.50227767
84ERBB20.50195267
85GRK50.49689286
86PLK30.49238020
87EPHB20.48436844
88PRKCE0.48135845
89LMTK20.47810765
90SIK10.47687665
91MKNK20.47498948
92PBK0.46259587
93ROCK20.46226904
94GRK70.45421402
95BRAF0.43859622
96STK110.43673016
97PRKCZ0.42099403
98MINK10.41070520
99RPS6KA20.40959569
100MAP3K20.40710425
101PRKG20.40584822
102ACVR1B0.40416766
103CAMKK20.40303796
104MYLK0.39981038
105CCNB10.39916170
106NEK20.39800443
107VRK10.39799743
108BMPR1B0.39736217
109CAMKK10.39688762
110CAMK1G0.39462081
111PKN10.39155960
112STK30.35294187
113CAMK2D0.34945305
114PRKG10.34840289
115PINK10.33764163
116FES0.33657608
117FGR0.33227787
118PAK30.33164966
119MARK30.32979820
120CSNK1D0.32903554
121EGFR0.32837346
122STK160.32354216
123ATM0.32287595
124CAMK40.32164155
125CDK50.31549251
126VRK20.31024411
127TTK0.30950519
128PRKCQ0.29374521
129ADRBK10.28847479
130PDPK10.27119998
131PRKACA0.26159202
132CAMK2G0.25484581
133PRKCH0.24196060
134MAPK70.22499766
135CDK150.22287467
136ROCK10.22121800
137GSK3A0.21992672
138CDK180.21298875
139CDK140.20995174
140DYRK30.19843440
141CDC42BPA0.19743657
142ERBB30.19399133
143PRKACB0.17105627
144DYRK1A0.16831394
145PRKCA0.16532372
146PRKD20.16296698
147PAK10.16074509
148DAPK10.16021632

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.69470442
2Olfactory transduction_Homo sapiens_hsa047403.16453952
3Huntingtons disease_Homo sapiens_hsa050162.86569747
4Collecting duct acid secretion_Homo sapiens_hsa049662.62772632
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.56116142
6Fatty acid biosynthesis_Homo sapiens_hsa000612.33257746
7Nicotine addiction_Homo sapiens_hsa050332.32775056
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.27407187
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.22376994
10Amphetamine addiction_Homo sapiens_hsa050312.21190404
11Ether lipid metabolism_Homo sapiens_hsa005652.20935481
12Butanoate metabolism_Homo sapiens_hsa006502.13525608
13Phototransduction_Homo sapiens_hsa047442.13342641
14Maturity onset diabetes of the young_Homo sapiens_hsa049502.12804857
15Synaptic vesicle cycle_Homo sapiens_hsa047212.01075058
16beta-Alanine metabolism_Homo sapiens_hsa004101.93628352
17Pyruvate metabolism_Homo sapiens_hsa006201.91021271
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.77419423
19Circadian entrainment_Homo sapiens_hsa047131.73986478
20Taste transduction_Homo sapiens_hsa047421.73294051
21Glutamatergic synapse_Homo sapiens_hsa047241.69737541
22Chemical carcinogenesis_Homo sapiens_hsa052041.69466428
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.69458325
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.66203909
25Linoleic acid metabolism_Homo sapiens_hsa005911.65879262
26Morphine addiction_Homo sapiens_hsa050321.57156773
27Primary bile acid biosynthesis_Homo sapiens_hsa001201.55759298
28Gastric acid secretion_Homo sapiens_hsa049711.54538161
29Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.53621557
30Basal transcription factors_Homo sapiens_hsa030221.52580388
31Nitrogen metabolism_Homo sapiens_hsa009101.51082539
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.48637233
33Renin secretion_Homo sapiens_hsa049241.48492914
34GABAergic synapse_Homo sapiens_hsa047271.48326701
35Protein export_Homo sapiens_hsa030601.47893848
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.47181393
37Dorso-ventral axis formation_Homo sapiens_hsa043201.45443184
38Vibrio cholerae infection_Homo sapiens_hsa051101.39292190
39Peroxisome_Homo sapiens_hsa041461.38783534
40Insulin secretion_Homo sapiens_hsa049111.36021078
41Calcium signaling pathway_Homo sapiens_hsa040201.35788551
42Histidine metabolism_Homo sapiens_hsa003401.35084419
43Long-term potentiation_Homo sapiens_hsa047201.32625296
44Oxidative phosphorylation_Homo sapiens_hsa001901.32032660
45Retinol metabolism_Homo sapiens_hsa008301.31766453
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.30919882
47Glucagon signaling pathway_Homo sapiens_hsa049221.30518576
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.29083294
49Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.28070370
50Salivary secretion_Homo sapiens_hsa049701.27364178
51Sphingolipid metabolism_Homo sapiens_hsa006001.15747948
52Oocyte meiosis_Homo sapiens_hsa041141.15258609
53Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.15213499
54Hedgehog signaling pathway_Homo sapiens_hsa043401.13281370
55Arachidonic acid metabolism_Homo sapiens_hsa005901.12284900
56Dopaminergic synapse_Homo sapiens_hsa047281.10330158
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08879724
58Glycerophospholipid metabolism_Homo sapiens_hsa005641.08621304
59Cardiac muscle contraction_Homo sapiens_hsa042601.07997883
60Steroid hormone biosynthesis_Homo sapiens_hsa001401.06202410
61Tryptophan metabolism_Homo sapiens_hsa003801.05408717
62Mineral absorption_Homo sapiens_hsa049781.04634832
63PPAR signaling pathway_Homo sapiens_hsa033201.04297732
64Rheumatoid arthritis_Homo sapiens_hsa053231.03265102
65Estrogen signaling pathway_Homo sapiens_hsa049151.02364340
66Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01769500
67cAMP signaling pathway_Homo sapiens_hsa040241.00356422
68Purine metabolism_Homo sapiens_hsa002301.00335365
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97029301
70Phenylalanine metabolism_Homo sapiens_hsa003600.95803413
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.94789173
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.94127290
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93700919
74Phagosome_Homo sapiens_hsa041450.92624966
75Ovarian steroidogenesis_Homo sapiens_hsa049130.92467953
76Propanoate metabolism_Homo sapiens_hsa006400.90952411
77Alzheimers disease_Homo sapiens_hsa050100.90737256
78ABC transporters_Homo sapiens_hsa020100.90583755
79Folate biosynthesis_Homo sapiens_hsa007900.87137781
80Fanconi anemia pathway_Homo sapiens_hsa034600.86094951
81Cocaine addiction_Homo sapiens_hsa050300.85033922
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.84401588
83Circadian rhythm_Homo sapiens_hsa047100.83251794
84Glutathione metabolism_Homo sapiens_hsa004800.81810175
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81724751
86Tyrosine metabolism_Homo sapiens_hsa003500.81000034
87Serotonergic synapse_Homo sapiens_hsa047260.80504210
88Thyroid hormone synthesis_Homo sapiens_hsa049180.76946491
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.76897910
90Glycerolipid metabolism_Homo sapiens_hsa005610.75681168
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.75275657
92Hippo signaling pathway_Homo sapiens_hsa043900.74938952
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73743844
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73137266
95Steroid biosynthesis_Homo sapiens_hsa001000.69864273
96Regulation of autophagy_Homo sapiens_hsa041400.67018492
97Fatty acid degradation_Homo sapiens_hsa000710.66874050
98Oxytocin signaling pathway_Homo sapiens_hsa049210.66583979
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65957352
100RNA degradation_Homo sapiens_hsa030180.65139845
101Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.63417944
102Axon guidance_Homo sapiens_hsa043600.63144891
103Selenocompound metabolism_Homo sapiens_hsa004500.62656675
104Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62307360
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.60633521
106Melanogenesis_Homo sapiens_hsa049160.60340690
107Wnt signaling pathway_Homo sapiens_hsa043100.60152472
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58677310
109Homologous recombination_Homo sapiens_hsa034400.58651366
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.57312502
111Parkinsons disease_Homo sapiens_hsa050120.57055312
112Arginine and proline metabolism_Homo sapiens_hsa003300.56746457
113Cholinergic synapse_Homo sapiens_hsa047250.56514544
114N-Glycan biosynthesis_Homo sapiens_hsa005100.56304236
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55731580
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55420414
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54072423
118Vitamin digestion and absorption_Homo sapiens_hsa049770.53567681
119Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53486863
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53139305
121Fatty acid elongation_Homo sapiens_hsa000620.52822401
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51616891
123Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.51510478
124Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50034230
125Basal cell carcinoma_Homo sapiens_hsa052170.49619582
126Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.48238924
127Starch and sucrose metabolism_Homo sapiens_hsa005000.47952925
128Fructose and mannose metabolism_Homo sapiens_hsa000510.47056574
129Tight junction_Homo sapiens_hsa045300.46945323
130Caffeine metabolism_Homo sapiens_hsa002320.46350623
131Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.45942625
132Type I diabetes mellitus_Homo sapiens_hsa049400.45321879
133Pancreatic secretion_Homo sapiens_hsa049720.44349173
134Cysteine and methionine metabolism_Homo sapiens_hsa002700.44329172
135Alcoholism_Homo sapiens_hsa050340.43981724
136Prion diseases_Homo sapiens_hsa050200.43686773
137SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39253966
138Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38819894
139GnRH signaling pathway_Homo sapiens_hsa049120.37001985
140Inositol phosphate metabolism_Homo sapiens_hsa005620.35916868
141Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35495587
142Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.35470426
143Gap junction_Homo sapiens_hsa045400.31578267
144Metabolic pathways_Homo sapiens_hsa011000.30294451

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