ENPEP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glomerular epithelial cell development (GO:0072310)9.10765243
2glomerular basement membrane development (GO:0032836)8.02233100
3regulation of guanylate cyclase activity (GO:0031282)7.32967701
4lipoprotein transport (GO:0042953)7.10504442
5NADH metabolic process (GO:0006734)6.97540346
6fat-soluble vitamin biosynthetic process (GO:0042362)6.45464134
7intestinal cholesterol absorption (GO:0030299)6.18914545
8positive regulation of guanylate cyclase activity (GO:0031284)5.83629561
9intestinal absorption (GO:0050892)5.78335013
10fructose metabolic process (GO:0006000)5.65049317
11triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.41215372
12glucuronate metabolic process (GO:0019585)5.24194861
13uronic acid metabolic process (GO:0006063)5.24194861
14adhesion of symbiont to host cell (GO:0044650)5.00809612
15virion attachment to host cell (GO:0019062)5.00809612
16regulation of cellular extravasation (GO:0002691)4.96554494
17drug catabolic process (GO:0042737)4.72836575
18* angiotensin maturation (GO:0002003)4.68410155
19regulation of cGMP biosynthetic process (GO:0030826)4.64216518
20regulation of triglyceride catabolic process (GO:0010896)4.42509547
21receptor guanylyl cyclase signaling pathway (GO:0007168)4.40539440
22regulation of bile acid biosynthetic process (GO:0070857)4.39299090
23erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.38769353
24L-phenylalanine catabolic process (GO:0006559)4.38769353
25regulation of cholesterol esterification (GO:0010872)4.31608209
26adhesion of symbiont to host (GO:0044406)4.29764309
27L-phenylalanine metabolic process (GO:0006558)4.24371821
28erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.24371821
29peptide catabolic process (GO:0043171)4.23649539
30phospholipid efflux (GO:0033700)4.22321467
31negative regulation of cholesterol transport (GO:0032375)4.18326003
32negative regulation of sterol transport (GO:0032372)4.18326003
33urea cycle (GO:0000050)4.10040255
34urea metabolic process (GO:0019627)4.10040255
35high-density lipoprotein particle remodeling (GO:0034375)4.07175677
36digestion (GO:0007586)4.04740938
37cysteine metabolic process (GO:0006534)4.04268790
38renal system process involved in regulation of blood volume (GO:0001977)4.03603899
39* regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.03475061
40* endocrine process (GO:0050886)4.03475061
41* regulation of systemic arterial blood pressure by hormone (GO:0001990)4.03475061
42glycolipid catabolic process (GO:0019377)4.03459095
43glycosphingolipid catabolic process (GO:0046479)4.01198726
44alpha-linolenic acid metabolic process (GO:0036109)4.00304804
45positive regulation of p38MAPK cascade (GO:1900745)4.00105384
46regulation of cholesterol homeostasis (GO:2000188)3.92458838
47aromatic amino acid family catabolic process (GO:0009074)3.92457849
48bile acid and bile salt transport (GO:0015721)3.92102627
49plasma lipoprotein particle assembly (GO:0034377)3.91738199
50vitamin A metabolic process (GO:0006776)3.91620286
51cholesterol efflux (GO:0033344)3.91554438
52positive regulation of lipoprotein lipase activity (GO:0051006)3.90855758
53positive regulation of triglyceride lipase activity (GO:0061365)3.90855758
54alkaloid metabolic process (GO:0009820)3.90381139
55homocysteine metabolic process (GO:0050667)3.88578735
56fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.87570168
57regulation of cGMP metabolic process (GO:0030823)3.86600024
58vitamin transport (GO:0051180)3.83621974
59reverse cholesterol transport (GO:0043691)3.82640083
60flavonoid metabolic process (GO:0009812)3.82470124
61vitamin transmembrane transport (GO:0035461)3.79363133
62lipoprotein metabolic process (GO:0042157)3.79279049
63drinking behavior (GO:0042756)3.78961059
64fat-soluble vitamin metabolic process (GO:0006775)3.78534974
65cholesterol homeostasis (GO:0042632)3.75286508
66cellular response to nitric oxide (GO:0071732)3.73609740
67* regulation of systemic arterial blood pressure (GO:0003073)3.72681500
68nitrogen cycle metabolic process (GO:0071941)3.71954062
69sterol homeostasis (GO:0055092)3.71367256
70protein-lipid complex assembly (GO:0065005)3.69449386
71arginine metabolic process (GO:0006525)3.69282927
72drug transmembrane transport (GO:0006855)3.68989545
73lysine catabolic process (GO:0006554)3.67341153
74lysine metabolic process (GO:0006553)3.67341153
75plasma lipoprotein particle remodeling (GO:0034369)3.65450448
76protein-lipid complex remodeling (GO:0034368)3.65450448
77macromolecular complex remodeling (GO:0034367)3.65450448
78regulation of vitamin metabolic process (GO:0030656)3.64418453
79antibacterial humoral response (GO:0019731)3.63087017
80surfactant homeostasis (GO:0043129)3.62387597
81* glomerulus development (GO:0032835)3.58273488
82positive regulation of cGMP biosynthetic process (GO:0030828)3.58023700
83sulfur amino acid catabolic process (GO:0000098)3.57592596
84maintenance of gastrointestinal epithelium (GO:0030277)3.55316427
85glyoxylate metabolic process (GO:0046487)3.54944926
86* peptide hormone processing (GO:0016486)3.54449087
87very-low-density lipoprotein particle assembly (GO:0034379)3.52912372
88phospholipid homeostasis (GO:0055091)3.51732015
89tryptophan catabolic process (GO:0006569)3.51059102
90indole-containing compound catabolic process (GO:0042436)3.51059102
91indolalkylamine catabolic process (GO:0046218)3.51059102
92antimicrobial humoral response (GO:0019730)3.50325961
93triglyceride homeostasis (GO:0070328)3.49932431
94acylglycerol homeostasis (GO:0055090)3.49932431
95positive regulation of glycoprotein biosynthetic process (GO:0010560)3.47702905
96epithelial cell differentiation involved in kidney development (GO:0035850)3.47289686
97glutamine family amino acid biosynthetic process (GO:0009084)3.47189752
98peptidyl-glutamic acid carboxylation (GO:0017187)3.45525180
99protein carboxylation (GO:0018214)3.45525180
100vitamin D metabolic process (GO:0042359)3.43472796
101bile acid metabolic process (GO:0008206)3.43113493
102kynurenine metabolic process (GO:0070189)3.41958466
103glycosylceramide metabolic process (GO:0006677)3.41581280
104bile acid biosynthetic process (GO:0006699)3.41060900
105midgut development (GO:0007494)3.40798663
106positive regulation of lipid catabolic process (GO:0050996)3.40037636
107exogenous drug catabolic process (GO:0042738)3.39126321
108omega-hydroxylase P450 pathway (GO:0097267)3.38955580
109cGMP biosynthetic process (GO:0006182)3.37366130
110plasma lipoprotein particle clearance (GO:0034381)3.36353313
111regulation of protein activation cascade (GO:2000257)3.35778675
112amino-acid betaine metabolic process (GO:0006577)3.32312164
113drug transport (GO:0015893)3.31917732
114tryptophan metabolic process (GO:0006568)3.30917756
115hormone catabolic process (GO:0042447)3.29129149
116response to nitric oxide (GO:0071731)3.27200207
117L-ascorbic acid metabolic process (GO:0019852)3.26812490
118vitamin biosynthetic process (GO:0009110)3.26713297
119regulation of complement activation (GO:0030449)3.22694633
120ceramide catabolic process (GO:0046514)3.22366550
121diacylglycerol metabolic process (GO:0046339)3.21103007
122cellular response to reactive nitrogen species (GO:1902170)3.20523831
123drug metabolic process (GO:0017144)3.19155132
124negative regulation of fibrinolysis (GO:0051918)3.15598582
125positive regulation of glycoprotein metabolic process (GO:1903020)3.15174410
126sphingomyelin metabolic process (GO:0006684)3.14655310
127mRNA modification (GO:0016556)3.13624841
128complement activation, alternative pathway (GO:0006957)3.13573299
129cholesterol transport (GO:0030301)3.11612871
130sterol transport (GO:0015918)3.11612871
131cytidine metabolic process (GO:0046087)3.11217480
132cytidine catabolic process (GO:0006216)3.11217480
133cytidine deamination (GO:0009972)3.11217480
134positive regulation of cGMP metabolic process (GO:0030825)3.10699315
135digestive system process (GO:0022600)3.10193001
136positive regulation of pseudopodium assembly (GO:0031274)3.08461324
137cellular glucuronidation (GO:0052695)3.07227810
138positive regulation of fatty acid biosynthetic process (GO:0045723)3.06470269
139glycerol metabolic process (GO:0006071)3.06277528
140cobalamin metabolic process (GO:0009235)3.04758363
141positive regulation of triglyceride metabolic process (GO:0090208)3.02333442
142renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.01964147
143sphingolipid catabolic process (GO:0030149)3.01658996
144urate metabolic process (GO:0046415)3.00200641
145plasma lipoprotein particle organization (GO:0071827)2.99466421
146epoxygenase P450 pathway (GO:0019373)2.98724089
147lipid homeostasis (GO:0055088)2.98560635
148serine family amino acid catabolic process (GO:0009071)2.97977365
149modified amino acid transport (GO:0072337)2.96924825
150transcytosis (GO:0045056)2.95651118
151positive regulation of fatty acid beta-oxidation (GO:0032000)2.93396905
152protein-lipid complex subunit organization (GO:0071825)2.92477547
153* regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.90217999
154fibrinolysis (GO:0042730)2.89189421
155fatty acid beta-oxidation (GO:0006635)2.88923867
156heme transport (GO:0015886)2.88082170
157regulation of fibrinolysis (GO:0051917)2.86339790
158regulation of p38MAPK cascade (GO:1900744)2.81818584
159chemical homeostasis within a tissue (GO:0048875)2.80037059
160aromatic amino acid family metabolic process (GO:0009072)2.79942197
161endothelial cell chemotaxis (GO:0035767)2.79439955
162low-density lipoprotein particle clearance (GO:0034383)2.78835987
163glomerular visceral epithelial cell development (GO:0072015)10.3186138

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse7.80819322
2RXR_22158963_ChIP-Seq_LIVER_Mouse5.54034923
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.10726072
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.64978029
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.62564773
6EGR1_23403033_ChIP-Seq_LIVER_Mouse3.77248202
7TP63_17297297_ChIP-ChIP_HaCaT_Human3.52659963
8* NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.28176819
9FOXO1_23066095_ChIP-Seq_LIVER_Mouse3.20358520
10TRIM28_21343339_ChIP-Seq_HEK293_Human3.01072403
11CDX2_20551321_ChIP-Seq_CACO-2_Human2.88699180
12* CLOCK_20551151_ChIP-Seq_293T_Human2.73215569
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.65112068
14* CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.52641667
15HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.31452184
16ESR1_21235772_ChIP-Seq_MCF-7_Human2.29573353
17SOX2_27498859_Chip-Seq_STOMACH_Mouse2.09756953
18ESR2_21235772_ChIP-Seq_MCF-7_Human2.09092831
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.89970244
20* GATA4_25053715_ChIP-Seq_YYC3_Human1.89526744
21RARG_19884340_ChIP-ChIP_MEFs_Mouse1.87510539
22FOXA2_19822575_ChIP-Seq_HepG2_Human1.80323272
23TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71149089
24PPAR_26484153_Chip-Seq_NCI-H1993_Human1.69789467
25TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.68334680
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.60772352
27CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.59493243
28PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.58070740
29SOX2_20726797_ChIP-Seq_SW620_Human1.54991150
30BP1_19119308_ChIP-ChIP_Hs578T_Human1.48161116
31* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.45854620
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.45455720
33FOXO3_23340844_ChIP-Seq_DLD1_Human1.43739302
34GATA6_25053715_ChIP-Seq_YYC3_Human1.41634820
35ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.40161027
36GATA1_22025678_ChIP-Seq_K562_Human1.39670767
37CDX2_19796622_ChIP-Seq_MESCs_Mouse1.37288081
38HNF4A_19822575_ChIP-Seq_HepG2_Human1.34861390
39CDX2_22108803_ChIP-Seq_LS180_Human1.34169357
40GATA2_21666600_ChIP-Seq_HMVEC_Human1.33408042
41ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.28757055
42TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.25705602
43BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.23811083
44NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.22953055
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.19800948
46FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17919105
47TCF4_18268006_ChIP-ChIP_LS174T_Human1.16177675
48SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.14470610
49TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.12460017
50CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.12449376
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11308024
52WT1_19549856_ChIP-ChIP_CCG9911_Human1.11087965
53RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.10882710
54AR_21909140_ChIP-Seq_LNCAP_Human1.10159444
55GATA2_19941826_ChIP-Seq_K562_Human1.08771095
56ESR1_20079471_ChIP-ChIP_T-47D_Human1.07410555
57ZNF263_19887448_ChIP-Seq_K562_Human1.04551517
58KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.03385219
59BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.03143868
60PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.02021856
61SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01445813
62STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.01073249
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.00240208
64LXR_22292898_ChIP-Seq_THP-1_Human0.99167683
65* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98484335
66KLF5_25053715_ChIP-Seq_YYC3_Human0.98373831
67EP300_21415370_ChIP-Seq_HL-1_Mouse0.97958310
68CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97442526
69EGR1_19032775_ChIP-ChIP_M12_Human0.97285893
70FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.96246084
71RACK7_27058665_Chip-Seq_MCF-7_Human0.95861778
72P63_26484246_Chip-Seq_KERATINOCYTES_Human0.93815409
73ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93299389
74RUNX1_27514584_Chip-Seq_MCF-7_Human0.92953890
75GATA1_19941826_ChIP-Seq_K562_Human0.92766864
76GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.92709455
77AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.92098232
78VDR_24787735_ChIP-Seq_THP-1_Human0.90658790
79SOX9_24532713_ChIP-Seq_HFSC_Mouse0.90000018
80ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.88616431
81IRF8_21731497_ChIP-ChIP_J774_Mouse0.87212517
82JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.86363450
83SA1_27219007_Chip-Seq_Bcells_Human0.84330306
84TBX20_22328084_ChIP-Seq_HEART_Mouse0.84026024
85TBX20_22080862_ChIP-Seq_HEART_Mouse0.84026024
86TCF3_18692474_ChIP-Seq_MEFs_Mouse0.83494677
87NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.81268035
88CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.80526340
89NR3C1_21868756_ChIP-Seq_MCF10A_Human0.79524473
90SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.78512294
91NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.78189483
92CJUN_26792858_Chip-Seq_BT549_Human0.77331746
93BCAT_22108803_ChIP-Seq_LS180_Human0.77244747
94MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.76888106
95EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.76579181
96VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.76578592
97AHR_22903824_ChIP-Seq_MCF-7_Human0.76308625
98FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.75841034
99P300_27058665_Chip-Seq_ZR-75-30cells_Human0.75693376
100* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.75658969
101HIF1A_21447827_ChIP-Seq_MCF-7_Human0.75613284
102NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.74747346
103FOXA1_21572438_ChIP-Seq_LNCaP_Human0.74464670
104CEBPB_22108803_ChIP-Seq_LS180_Human0.74390944
105TP53_18474530_ChIP-ChIP_U2OS_Human0.74372821
106JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.74353571
107Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.73983769
108PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.73453408
109CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.73059291
110NANOG_20526341_ChIP-Seq_ESCs_Human0.72856468
111HNFA_21074721_ChIP-Seq_CACO-2_Human0.72808721
112GATA3_24758297_ChIP-Seq_MCF-7_Human0.72487588
113CBP_21632823_ChIP-Seq_H3396_Human0.72137525
114CTCF_27219007_Chip-Seq_Bcells_Human0.72134693
115FOXM1_26456572_ChIP-Seq_MCF-7_Human0.72110312
116BCOR_27268052_Chip-Seq_Bcells_Human0.71397752
117TET1_21451524_ChIP-Seq_MESCs_Mouse0.71060839
118* SMAD3_21741376_ChIP-Seq_HESCs_Human0.70705491
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.70537777
120PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.69468525
121ATF3_27146783_Chip-Seq_COLON_Human0.68188810
122RXR_22108803_ChIP-Seq_LS180_Human0.67883057
123CREB1_26743006_Chip-Seq_LNCaP_Human0.67759007
124FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.65769756
125KDM2B_26808549_Chip-Seq_K562_Human0.64116494
126* FOXA1_25552417_ChIP-Seq_VCAP_Human0.64004406
127RAD21_21589869_ChIP-Seq_MESCs_Mouse0.63718438
128TP63_23658742_ChIP-Seq_EP156T_Human0.63265502
129ELK3_25401928_ChIP-Seq_HUVEC_Human0.63076197
130IRF8_22096565_ChIP-ChIP_GC-B_Human0.62781918

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.44083824
2MP0002139_abnormal_hepatobiliary_system6.04159054
3MP0005085_abnormal_gallbladder_physiolo4.79058188
4MP0005365_abnormal_bile_salt4.17413589
5MP0001666_abnormal_nutrient_absorption3.80950958
6MP0008875_abnormal_xenobiotic_pharmacok3.80724952
7MP0003252_abnormal_bile_duct3.60466400
8MP0009840_abnormal_foam_cell3.58105178
9MP0010329_abnormal_lipoprotein_level3.15917052
10MP0009379_abnormal_foot_pigmentation3.08825008
11MP0005332_abnormal_amino_acid2.94868036
12MP0010155_abnormal_intestine_physiology2.31204848
13MP0010368_abnormal_lymphatic_system2.27973157
14MP0003806_abnormal_nucleotide_metabolis2.24405723
15MP0004019_abnormal_vitamin_homeostasis2.22421857
16MP0009643_abnormal_urine_homeostasis2.21645027
17MP0003191_abnormal_cellular_cholesterol2.03934764
18MP0005409_darkened_coat_color1.88776931
19MP0004272_abnormal_basement_membrane1.87642697
20MP0003705_abnormal_hypodermis_morpholog1.87328518
21MP0001664_abnormal_digestion1.80204002
22MP0002118_abnormal_lipid_homeostasis1.80182246
23MP0000609_abnormal_liver_physiology1.64816734
24MP0002136_abnormal_kidney_physiology1.60582938
25MP0002138_abnormal_hepatobiliary_system1.57639637
26MP0000537_abnormal_urethra_morphology1.55329583
27MP0001661_extended_life_span1.54952025
28MP0010234_abnormal_vibrissa_follicle1.53359115
29MP0001879_abnormal_lymphatic_vessel1.47851402
30MP0005319_abnormal_enzyme/_coenzyme1.45275484
31MP0005083_abnormal_biliary_tract1.44997472
32MP0000678_abnormal_parathyroid_gland1.43138527
33MP0001756_abnormal_urination1.39853132
34MP0004264_abnormal_extraembryonic_tissu1.38378384
35MP0000490_abnormal_crypts_of1.32672036
36MP0003879_abnormal_hair_cell1.32532757
37MP0005167_abnormal_blood-brain_barrier1.26854953
38MP0005084_abnormal_gallbladder_morpholo1.24239471
39MP0000230_abnormal_systemic_arterial1.23695018
40MP0000462_abnormal_digestive_system1.23172046
41MP0009384_cardiac_valve_regurgitation1.21763560
42MP0003195_calcinosis1.21623207
43MP0001501_abnormal_sleep_pattern1.20949439
44MP0003718_maternal_effect1.19707978
45MP0005451_abnormal_body_composition1.15829020
46MP0003183_abnormal_peptide_metabolism1.14304202
47MP0004858_abnormal_nervous_system1.14271760
48MP0005623_abnormal_meninges_morphology1.11859319
49MP0005584_abnormal_enzyme/coenzyme_acti1.11387086
50MP0002135_abnormal_kidney_morphology1.08304716
51MP0003300_gastrointestinal_ulcer1.07613922
52MP0001188_hyperpigmentation1.01620847
53MP0005535_abnormal_body_temperature1.00137501
54MP0004043_abnormal_pH_regulation0.99279789
55MP0004782_abnormal_surfactant_physiolog0.97703522
56MP0001873_stomach_inflammation0.97180583
57MP0002822_catalepsy0.90491619
58MP0005670_abnormal_white_adipose0.88641745
59MP0009697_abnormal_copulation0.86635460
60MP0000598_abnormal_liver_morphology0.86222194
61MP0005666_abnormal_adipose_tissue0.86028903
62MP0003868_abnormal_feces_composition0.85974483
63MP0004185_abnormal_adipocyte_glucose0.85654705
64MP0001764_abnormal_homeostasis0.85333883
65MP0004084_abnormal_cardiac_muscle0.85142789
66MP0001663_abnormal_digestive_system0.82600949
67MP0004270_analgesia0.81293910
68MP0009642_abnormal_blood_homeostasis0.80781693
69MP0002254_reproductive_system_inflammat0.79840677
70MP0000477_abnormal_intestine_morphology0.78942092
71MP0005636_abnormal_mineral_homeostasis0.78541754
72MP0002796_impaired_skin_barrier0.77565478
73MP0002295_abnormal_pulmonary_circulatio0.77210698
74MP0005448_abnormal_energy_balance0.76572394
75MP0006138_congestive_heart_failure0.74146344
76MP0000604_amyloidosis0.73481520
77MP0004130_abnormal_muscle_cell0.73192604
78MP0002971_abnormal_brown_adipose0.73130349
79MP0001845_abnormal_inflammatory_respons0.72983697
80MP0001765_abnormal_ion_homeostasis0.70802022
81MP0006082_CNS_inflammation0.70497066
82MP0002876_abnormal_thyroid_physiology0.70195130
83MP0009053_abnormal_anal_canal0.70090811
84MP0008469_abnormal_protein_level0.70080502
85MP0009785_altered_susceptibility_to0.69058354
86MP0001485_abnormal_pinna_reflex0.68290423
87MP0002396_abnormal_hematopoietic_system0.68120952
88MP0008961_abnormal_basal_metabolism0.67900269
89MP0010352_gastrointestinal_tract_polyps0.66596146
90MP0004036_abnormal_muscle_relaxation0.66387544
91MP0005166_decreased_susceptibility_to0.65774954
92MP0000534_abnormal_ureter_morphology0.65499967
93MP0002896_abnormal_bone_mineralization0.64119447
94MP0000538_abnormal_urinary_bladder0.61717172
95MP0008872_abnormal_physiological_respon0.61328394
96MP0005375_adipose_tissue_phenotype0.60017852
97MP0003866_abnormal_defecation0.60002988
98MP0003724_increased_susceptibility_to0.59148378
99MP0005023_abnormal_wound_healing0.57915623
100MP0002078_abnormal_glucose_homeostasis0.57396043
101MP0005334_abnormal_fat_pad0.57085486
102MP0004147_increased_porphyrin_level0.55236445
103MP0003566_abnormal_cell_adhesion0.54289731
104MP0002128_abnormal_blood_circulation0.53358364
105MP0005377_hearing/vestibular/ear_phenot0.53164832
106MP0003878_abnormal_ear_physiology0.53164832
107MP0003115_abnormal_respiratory_system0.52223144
108MP0005381_digestive/alimentary_phenotyp0.52033589
109MP0001881_abnormal_mammary_gland0.51492653
110MP0009764_decreased_sensitivity_to0.51013921
111MP0009115_abnormal_fat_cell0.50592024
112MP0008775_abnormal_heart_ventricle0.49835163
113MP0002098_abnormal_vibrissa_morphology0.48998439
114MP0009763_increased_sensitivity_to0.47972348
115MP0005187_abnormal_penis_morphology0.47691621
116MP0004484_altered_response_of0.47449994
117MP0000579_abnormal_nail_morphology0.47151276
118MP0003953_abnormal_hormone_level0.47090450
119MP0000249_abnormal_blood_vessel0.46985627
120MP0003638_abnormal_response/metabolism_0.46982739
121MP0000465_gastrointestinal_hemorrhage0.46754172
122MP0005501_abnormal_skin_physiology0.46458063
123MP0005376_homeostasis/metabolism_phenot0.46028706
124MP0000013_abnormal_adipose_tissue0.45763345
125MP0005503_abnormal_tendon_morphology0.45490567
126MP0010678_abnormal_skin_adnexa0.45314652
127MP0003656_abnormal_erythrocyte_physiolo0.45156613
128MP0000003_abnormal_adipose_tissue0.44283381
129MP0000516_abnormal_urinary_system0.43936200
130MP0005367_renal/urinary_system_phenotyp0.43421479
131MP0005395_other_phenotype0.42583634
132MP0002166_altered_tumor_susceptibility0.42237923
133MP0003329_amyloid_beta_deposits0.42105765
134MP0002998_abnormal_bone_remodeling0.41654721
135MP0005165_increased_susceptibility_to0.41186191

Predicted human phenotypes

RankGene SetZ-score
1Mesangial abnormality (HP:0001966)6.90678948
2Focal segmental glomerulosclerosis (HP:0000097)6.52343768
3Abnormality of glutamine family amino acid metabolism (HP:0010902)5.61199649
4Deep venous thrombosis (HP:0002625)5.42900967
5Glomerulosclerosis (HP:0000096)5.35289751
6Hypobetalipoproteinemia (HP:0003563)5.32599484
7Chronic diarrhea (HP:0002028)5.11343678
8Abnormality of the vitamin B12 metabolism (HP:0004341)5.05268366
9Xanthomatosis (HP:0000991)4.83543431
10Hypoalbuminemia (HP:0003073)4.76811833
11Abnormal albumin level (HP:0012116)4.76811833
12Intrahepatic cholestasis (HP:0001406)4.72179445
13Abnormality of vitamin B metabolism (HP:0004340)4.70876375
14Abnormality of monocarboxylic acid metabolism (HP:0010996)4.62405951
15Nephritis (HP:0000123)4.47921404
16Glomerulonephritis (HP:0000099)4.37875765
17Confusion (HP:0001289)4.35018879
18Systemic lupus erythematosus (HP:0002725)4.21142733
19Hydroxyprolinuria (HP:0003080)4.06956450
20Abnormality of proline metabolism (HP:0010907)4.06956450
21Hyperglycinuria (HP:0003108)4.00629104
22Hypolipoproteinemia (HP:0010981)3.77115726
23Abnormality of aromatic amino acid family metabolism (HP:0004338)3.72905081
24Conjugated hyperbilirubinemia (HP:0002908)3.71063161
25Nausea (HP:0002018)3.64248380
26Fat malabsorption (HP:0002630)3.62812121
27Wide cranial sutures (HP:0010537)3.55288466
28Hyperlipoproteinemia (HP:0010980)3.44551720
29Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.43945547
30Ileus (HP:0002595)3.43885665
31Abnormality of serine family amino acid metabolism (HP:0010894)3.42612531
32Abnormality of glycine metabolism (HP:0010895)3.42612531
33Autoimmune thrombocytopenia (HP:0001973)3.30732645
34Acanthocytosis (HP:0001927)3.30207297
35Thin bony cortex (HP:0002753)3.29336414
36Epidermoid cyst (HP:0200040)3.25647073
37Hyperammonemia (HP:0001987)3.21581331
38Malnutrition (HP:0004395)3.19479391
39Prolonged partial thromboplastin time (HP:0003645)3.14768485
40Abnormality of sulfur amino acid metabolism (HP:0004339)3.14404921
41Polycythemia (HP:0001901)3.09636418
42Abnormality of aspartate family amino acid metabolism (HP:0010899)3.08216883
43Potter facies (HP:0002009)3.04601887
44Facial shape deformation (HP:0011334)3.04601887
45Abnormality of purine metabolism (HP:0004352)3.03832753
46Megaloblastic anemia (HP:0001889)3.00375501
47Hypercholesterolemia (HP:0003124)2.94279894
48Complement deficiency (HP:0004431)2.92870641
49Metabolic alkalosis (HP:0200114)2.92075875
50Congenital sensorineural hearing impairment (HP:0008527)2.85605291
51Posterior subcapsular cataract (HP:0007787)2.84688375
52Gout (HP:0001997)2.82012483
53Abnormality of the common coagulation pathway (HP:0010990)2.80721245
54Decreased circulating renin level (HP:0003351)2.79241350
55Abnormal urine phosphate concentration (HP:0012599)2.78946493
56Ketosis (HP:0001946)2.77178340
57Stage 5 chronic kidney disease (HP:0003774)2.75739672
58Hypoglycemic coma (HP:0001325)2.75593398
59Hypoalphalipoproteinemia (HP:0003233)2.73600525
60Abnormality of nucleobase metabolism (HP:0010932)2.65321204
61Hyperglycinemia (HP:0002154)2.57367520
62Right ventricular cardiomyopathy (HP:0011663)2.54517138
63Esophageal varix (HP:0002040)2.48800470
64Abnormality of renin-angiotensin system (HP:0000847)2.47966892
65Enlarged epiphyses (HP:0010580)2.47720385
66Abnormal tarsal ossification (HP:0008369)2.46756305
67Ketoacidosis (HP:0001993)2.43053418
68Abnormality of fatty-acid metabolism (HP:0004359)2.40896045
69Delayed epiphyseal ossification (HP:0002663)2.40593216
70Abdominal distention (HP:0003270)2.38842958
71Abnormality of the intrinsic pathway (HP:0010989)2.38447443
72Lymphangioma (HP:0100764)2.38370268
73Pigmentary retinal degeneration (HP:0001146)2.37967198
74Abnormal glucose tolerance (HP:0001952)2.37177961
75Vascular calcification (HP:0004934)2.35003354
76Abnormality of magnesium homeostasis (HP:0004921)2.34751249
77Proteinuria (HP:0000093)2.34227926
78Hemorrhage of the eye (HP:0011885)2.33592274
79Joint hemorrhage (HP:0005261)2.32803490
80Tubulointerstitial fibrosis (HP:0005576)2.30835222
81Hypotension (HP:0002615)2.30518761
82Hyperparathyroidism (HP:0000843)2.29375141
83Hypoproteinemia (HP:0003075)2.28550467
84Abnormality of small intestinal villus morphology (HP:0011472)2.25726336
85Villous atrophy (HP:0011473)2.25726336
86Hypophosphatemia (HP:0002148)2.24409773
87Visceral angiomatosis (HP:0100761)2.24386922
88Abnormality of the costochondral junction (HP:0000919)2.23881018
89Nephrotic syndrome (HP:0000100)2.22171791
90Renal tubular acidosis (HP:0001947)2.21749645
91Subcapsular cataract (HP:0000523)2.18407073
92Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.17860346
93Metabolic acidosis (HP:0001942)2.17774024
94Cardiovascular calcification (HP:0011915)2.16383177
95Neonatal respiratory distress (HP:0002643)2.16045566
96Hyperbilirubinemia (HP:0002904)2.15909755
97Sensorimotor neuropathy (HP:0007141)2.15875098
98Tubular atrophy (HP:0000092)2.13749382
99Nephrolithiasis (HP:0000787)2.13490513
100Skin nodule (HP:0200036)2.13417306
101Eczematoid dermatitis (HP:0000976)2.11562284
102Hyperphosphatemia (HP:0002905)2.09315660
103Interstitial pulmonary disease (HP:0006530)2.07785437
104Hematuria (HP:0000790)2.06412842
105Cerebral palsy (HP:0100021)2.06277091
106Hemangiomatosis (HP:0007461)2.05094202
107Corneal erosion (HP:0200020)2.03950088
108Protuberant abdomen (HP:0001538)2.03940360
109Myocardial infarction (HP:0001658)2.02747804
110Abnormality of complement system (HP:0005339)2.01516608
111Hyperactive renin-angiotensin system (HP:0000841)2.00936490
112Metaphyseal cupping (HP:0003021)2.00086776
113Pancreatitis (HP:0001733)1.98030397
114Glycosuria (HP:0003076)1.97355944
115Abnormality of urine glucose concentration (HP:0011016)1.97355944
116Poikilocytosis (HP:0004447)1.95822798
117Increased purine levels (HP:0004368)1.92633235
118Hyperuricemia (HP:0002149)1.92633235
119Renal tubular dysfunction (HP:0000124)1.92353431
120Alkalosis (HP:0001948)1.90759271
121Late onset (HP:0003584)1.89913499
122Abnormality of alkaline phosphatase activity (HP:0004379)1.89345863
123Proximal tubulopathy (HP:0000114)1.89263872
124Abnormal enzyme/coenzyme activity (HP:0012379)1.89123236
125Abnormality of pyrimidine metabolism (HP:0004353)1.88298106
126Chorioretinal atrophy (HP:0000533)1.88180690
127Irritability (HP:0000737)1.87882087
128Steatorrhea (HP:0002570)1.87664110
129Delayed CNS myelination (HP:0002188)1.83332915
130Widely patent fontanelles and sutures (HP:0004492)1.82849348
131Hepatocellular carcinoma (HP:0001402)1.82223918
132Osteomalacia (HP:0002749)1.81180240
133Amyloidosis (HP:0011034)1.80878705
134Rickets (HP:0002748)1.80224173
135Increased circulating renin level (HP:0000848)1.78269088
136Hypophosphatemic rickets (HP:0004912)1.75581221
137Hypokalemia (HP:0002900)1.75578539
138Chondrocalcinosis (HP:0000934)1.75345887
139Polar cataract (HP:0010696)1.74939261
140Gingivitis (HP:0000230)1.74571363
141Abnormality of methionine metabolism (HP:0010901)1.72141510
142Abnormality of vitamin metabolism (HP:0100508)1.71996802
143Hyperphosphaturia (HP:0003109)1.71956523
144Growth hormone excess (HP:0000845)1.71026707
145Generalized aminoaciduria (HP:0002909)1.70768885
146Gastrointestinal dysmotility (HP:0002579)1.69904833
147Abnormality of dicarboxylic acid metabolism (HP:0010995)1.69647750
148Dicarboxylic aciduria (HP:0003215)1.69647750
149Dehydration (HP:0001944)1.64253173

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B7.99425964
2FRK3.77057273
3EPHB23.61219124
4ERN13.36582106
5TIE12.90573470
6MST42.83799304
7EPHA22.75810734
8FGFR42.73067075
9MST1R2.52330285
10WNK42.48399449
11SIK12.43825486
12MYLK2.37685415
13TRIB32.34492328
14KDR2.27956206
15PAK42.22065689
16BCKDK2.19320364
17RIPK12.18591968
18TGFBR22.06909446
19PTK62.01650198
20LATS12.01031455
21TNIK1.98790186
22AKT31.90044884
23OXSR11.88165832
24MAP3K101.85281166
25GRK61.82853557
26MAP3K121.76150974
27EPHB11.72504942
28LMTK21.60947023
29FGFR21.53819733
30CAMK1D1.43770549
31MAP3K71.41399545
32PRKG21.40033164
33PDGFRA1.35228119
34NME11.34183854
35STK391.25411870
36NLK1.21806140
37LRRK21.19820098
38MET1.17338842
39TAOK31.15500677
40MAP2K21.14262376
41TESK21.11416112
42PKN21.11107235
43TYK21.10681522
44STK101.07396228
45INSRR1.07193934
46FER1.06452795
47TGFBR11.01868355
48MATK0.98094186
49MAPK110.97296135
50MAP3K20.95787135
51CASK0.93801653
52EPHA40.91794781
53CAMK1G0.89972118
54PRKAA20.89411990
55GSK3A0.89164999
56PTK20.88637568
57MAP2K10.87605920
58MAP2K60.86659324
59NEK90.85705849
60MAP3K30.85692370
61STK240.84226339
62FGFR30.83373598
63PAK20.72851482
64JAK10.72056035
65EPHA30.71016801
66ABL20.70342230
67PRPF4B0.70261572
68CDC42BPA0.69507725
69PDPK10.69225221
70MAP4K10.69071563
71PDK20.67012529
72BMX0.66873223
73TESK10.65222607
74PAK30.64670063
75JAK20.63907404
76STK30.61694932
77NUAK10.61694749
78PIM10.60898416
79TBK10.60335498
80PRKCA0.59567459
81BCR0.58957126
82PRKAA10.58730054
83MAP2K30.58520338
84GRK10.58369399
85PRKCZ0.57545600
86ROCK10.55622012
87STK38L0.54380892
88ERBB20.54036373
89PIK3CG0.53287097
90PDGFRB0.52242900
91RET0.51274170
92BMPR20.50852492
93CDK60.50362400
94CAMK2B0.49904005
95ERBB40.49159998
96MAPK150.49018249
97DYRK1B0.47402137
98CSK0.46381090
99MTOR0.46318713
100SGK30.44516599
101PRKACG0.44313361
102IRAK10.41439709
103DAPK20.41078654
104NEK60.40835596
105MELK0.40508403
106MAP3K80.40308885
107PDK30.40129059
108PDK40.40129059
109MAP3K110.39798632
110ZAP700.39765974
111PRKCD0.39655566
112MAPK40.39441982
113CAMK2D0.39168910
114CAMK2G0.39081907
115TAOK10.38927781
116PIK3CA0.38646220
117DDR20.38306014
118IGF1R0.37590898
119CSF1R0.36093549
120PDK10.35915964
121FGFR10.35065702
122RIPK40.34187881
123FLT30.32908380
124NTRK10.32528983
125PRKD10.32294956
126MAP3K10.31829930
127MAPK70.30444083
128MAPK120.30434099
129KSR20.30368052
130FYN0.29969564
131SRC0.29942309
132PRKCI0.28043515
133YES10.27401442
134KIT0.25488309
135ITK0.24746028
136OBSCN0.22100599
137MAPKAPK20.21699310
138MAP3K140.20872924
139PRKACA0.20863777
140TEC0.19176551

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049753.19250855
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.12976741
3Primary bile acid biosynthesis_Homo sapiens_hsa001202.98664232
4Nitrogen metabolism_Homo sapiens_hsa009102.88097926
5Caffeine metabolism_Homo sapiens_hsa002322.56485773
6Arginine biosynthesis_Homo sapiens_hsa002202.48651300
7Tryptophan metabolism_Homo sapiens_hsa003802.43900682
8Vitamin digestion and absorption_Homo sapiens_hsa049772.38529777
9Fatty acid degradation_Homo sapiens_hsa000712.36288280
10PPAR signaling pathway_Homo sapiens_hsa033202.19679173
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.08135449
12Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.05993451
13Linoleic acid metabolism_Homo sapiens_hsa005912.04854473
14Bile secretion_Homo sapiens_hsa049762.04716282
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.04492428
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.03885560
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.02173134
18Histidine metabolism_Homo sapiens_hsa003401.97834091
19Starch and sucrose metabolism_Homo sapiens_hsa005001.96463804
20Complement and coagulation cascades_Homo sapiens_hsa046101.89249666
21* Renin-angiotensin system_Homo sapiens_hsa046141.84384061
22Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.78172042
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.75052007
24Propanoate metabolism_Homo sapiens_hsa006401.68524687
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.65381107
26Butanoate metabolism_Homo sapiens_hsa006501.64811662
27Peroxisome_Homo sapiens_hsa041461.64795911
28Protein digestion and absorption_Homo sapiens_hsa049741.63517605
29Fatty acid metabolism_Homo sapiens_hsa012121.63180561
30Folate biosynthesis_Homo sapiens_hsa007901.60843666
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.59329660
32Cyanoamino acid metabolism_Homo sapiens_hsa004601.58953157
332-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.58899259
34Mineral absorption_Homo sapiens_hsa049781.54023725
35Sulfur metabolism_Homo sapiens_hsa009201.53555543
36beta-Alanine metabolism_Homo sapiens_hsa004101.52053905
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.50354367
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.47456783
39Arachidonic acid metabolism_Homo sapiens_hsa005901.43649959
40Chemical carcinogenesis_Homo sapiens_hsa052041.39950670
41Maturity onset diabetes of the young_Homo sapiens_hsa049501.37354069
42Drug metabolism - other enzymes_Homo sapiens_hsa009831.34863896
43Pyruvate metabolism_Homo sapiens_hsa006201.31588551
44ABC transporters_Homo sapiens_hsa020101.30440806
45Galactose metabolism_Homo sapiens_hsa000521.24673826
46Retinol metabolism_Homo sapiens_hsa008301.24145574
47Glycerolipid metabolism_Homo sapiens_hsa005611.22992014
48Steroid hormone biosynthesis_Homo sapiens_hsa001401.19077728
49Selenocompound metabolism_Homo sapiens_hsa004501.14685119
50Carbon metabolism_Homo sapiens_hsa012001.07392087
51Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04859958
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.04073294
53Glutathione metabolism_Homo sapiens_hsa004801.00242641
54Phenylalanine metabolism_Homo sapiens_hsa003601.00224537
55Arginine and proline metabolism_Homo sapiens_hsa003300.98316414
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.96348771
57Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.95302934
58Lysine degradation_Homo sapiens_hsa003100.92494079
59Ether lipid metabolism_Homo sapiens_hsa005650.91847278
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88925754
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83765985
62ECM-receptor interaction_Homo sapiens_hsa045120.83413019
63Staphylococcus aureus infection_Homo sapiens_hsa051500.83392028
64Fructose and mannose metabolism_Homo sapiens_hsa000510.79824051
65Fatty acid biosynthesis_Homo sapiens_hsa000610.78900486
66Biosynthesis of amino acids_Homo sapiens_hsa012300.77328139
67Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76502316
68Asthma_Homo sapiens_hsa053100.75914881
69Fatty acid elongation_Homo sapiens_hsa000620.75532382
70Intestinal immune network for IgA production_Homo sapiens_hsa046720.73694797
71Tyrosine metabolism_Homo sapiens_hsa003500.73269491
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.63849534
73Pentose phosphate pathway_Homo sapiens_hsa000300.63235407
74Pancreatic secretion_Homo sapiens_hsa049720.54406309
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.52229728
76Steroid biosynthesis_Homo sapiens_hsa001000.51920517
77Allograft rejection_Homo sapiens_hsa053300.50506733
78Amoebiasis_Homo sapiens_hsa051460.49792872
79Insulin resistance_Homo sapiens_hsa049310.48598294
80Graft-versus-host disease_Homo sapiens_hsa053320.46961744
81Autoimmune thyroid disease_Homo sapiens_hsa053200.46570742
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45528368
83Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44795722
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43411634
85Small cell lung cancer_Homo sapiens_hsa052220.41627900
86Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39036170
87Sulfur relay system_Homo sapiens_hsa041220.38580056
88Glycerophospholipid metabolism_Homo sapiens_hsa005640.35973344
89Thyroid hormone synthesis_Homo sapiens_hsa049180.35926553
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.35513380
91Focal adhesion_Homo sapiens_hsa045100.33864012
92Renin secretion_Homo sapiens_hsa049240.33363940
93Other glycan degradation_Homo sapiens_hsa005110.32161423
94Metabolic pathways_Homo sapiens_hsa011000.31793974
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.28460141
96Sphingolipid metabolism_Homo sapiens_hsa006000.23791689
97Tight junction_Homo sapiens_hsa045300.23660840
98Type I diabetes mellitus_Homo sapiens_hsa049400.23437132
99Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21822794
100Bladder cancer_Homo sapiens_hsa052190.20008742
101AMPK signaling pathway_Homo sapiens_hsa041520.19121730
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19053558
103Adherens junction_Homo sapiens_hsa045200.18676161
104AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.17071361
105Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.16607287
106Cocaine addiction_Homo sapiens_hsa050300.15817835
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.15465729
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.14689342
109Pertussis_Homo sapiens_hsa051330.12762916
110Leukocyte transendothelial migration_Homo sapiens_hsa046700.11533267
111Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.10782395
112Antigen processing and presentation_Homo sapiens_hsa046120.10683169
113Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.10471193
114Serotonergic synapse_Homo sapiens_hsa047260.08589850
115Hepatitis C_Homo sapiens_hsa051600.08281719
116N-Glycan biosynthesis_Homo sapiens_hsa005100.06844152
117African trypanosomiasis_Homo sapiens_hsa051430.05953628
118Insulin secretion_Homo sapiens_hsa049110.05233802
119Type II diabetes mellitus_Homo sapiens_hsa049300.02651552
120Leishmaniasis_Homo sapiens_hsa051400.01832172
121Insulin signaling pathway_Homo sapiens_hsa049100.01556843
122Glucagon signaling pathway_Homo sapiens_hsa049220.01434536
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.01360482
124Ovarian steroidogenesis_Homo sapiens_hsa049130.01008679

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